Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2wt0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 6.A NH1 THR 133.A O no hydrogen 2.645 N/A LEU 11.A N ALA 124.A O no hydrogen 2.869 N/A LEU 13.A N THR 122.A O no hydrogen 2.726 N/A GLY 16.A N LEU 13.A O no hydrogen 2.841 N/A GLY 20.A N ILE 97.A O no hydrogen 2.634 N/A ALA 21.A N PRO 18.A O no hydrogen 3.022 N/A SER 22.A N TYR 138.A O no hydrogen 2.940 N/A ILE 23.A N ILE 95.A O no hydrogen 2.841 N/A VAL 24.A N THR 136.A O no hydrogen 2.774 N/A LEU 25.A N LEU 93.A O no hydrogen 2.800 N/A GLU 26.A N ARG 134.A O no hydrogen 2.880 N/A GLY 27.A N PHE 91.A O no hydrogen 3.278 N/A THR 28.A N VAL 131.A O no hydrogen 2.935 N/A THR 30.A N ASP 129.A O no hydrogen 3.089 N/A THR 30.A OG1 ASP 129.A O no hydrogen 3.413 N/A SER 32.A OG SER 32.A O no hydrogen 2.632 N/A ALA 33.A N THR 30.A O no hydrogen 3.111 N/A VAL 34.A N ASP 129.A OD2 no hydrogen 2.800 N/A PHE 35.A N ASP 129.A OD2 no hydrogen 3.192 N/A PHE 36.A N VAL 53.A O no hydrogen 3.111 N/A THR 37.A N SER 127.A O no hydrogen 2.796 N/A LEU 38.A N PHE 51.A O no hydrogen 2.866 N/A ASP 39.A N SER 125.A O no hydrogen 2.892 N/A LEU 40.A N LEU 49.A O no hydrogen 2.823 N/A VAL 41.A N ARG 123.A O no hydrogen 2.856 N/A THR 42.A N SER 46.A O no hydrogen 2.966 N/A THR 42.A OG1 GLN 119.A O no hydrogen 2.680 N/A THR 42.A OG1 GLY 120.A O no hydrogen 2.673 N/A GLY 43.A N THR 122.A OG1 no hydrogen 3.405 N/A SER 46.A N PRO 44.A O no hydrogen 2.988 N/A LEU 47.A N ARG 68.A O no hydrogen 2.819 N/A ALA 48.A N LEU 40.A O no hydrogen 2.902 N/A LEU 49.A N LEU 40.A O no hydrogen 3.290 N/A HIS 50.A N ASN 66.A O no hydrogen 2.712 N/A HIS 50.A ND1 ASP 39.A OD1 no hydrogen 2.794 N/A PHE 51.A N LEU 38.A O no hydrogen 2.889 N/A ASN 52.A N VAL 64.A O no hydrogen 2.866 N/A ASN 52.A ND2 PHE 36.A O no hydrogen 3.551 N/A ASN 52.A ND2 THR 37.A OG1 no hydrogen 2.827 N/A VAL 53.A N PHE 36.A O no hydrogen 2.728 N/A ARG 54.A N HIS 62.A O no hydrogen 2.798 N/A ARG 54.A NE ASN 52.A OD1 no hydrogen 2.651 N/A ARG 54.A NH2 ASN 52.A OD1 no hydrogen 3.263 N/A LEU 55.A N VAL 34.A O no hydrogen 2.907 N/A HIS 62.A N ARG 54.A O no hydrogen 2.906 N/A VAL 64.A N ASN 52.A O no hydrogen 2.876 N/A CYS 65.A N VAL 78.A O no hydrogen 2.878 N/A ASN 66.A N HIS 50.A O no hydrogen 3.028 N/A ASN 66.A ND2 GLY 75.A O no hydrogen 3.072 N/A SER 67.A N ASN 66.A OD1 no hydrogen 2.819 N/A ARG 68.A N LEU 47.A O no hydrogen 2.986 N/A ARG 68.A NE GLY 70.A O no hydrogen 2.910 N/A ARG 68.A NH2 ALA 45.A O no hydrogen 2.906 N/A GLU 69.A N ASN 73.A O no hydrogen 2.935 N/A GLY 70.A N SER 46.A OG no hydrogen 2.942 N/A GLY 75.A N SER 67.A O no hydrogen 2.924 N/A VAL 78.A N CYS 65.A O no hydrogen 2.884 N/A ARG 79.A NE GLU 77.A OE2 no hydrogen 3.164 N/A ARG 79.A NH2 GLU 77.A OE2 no hydrogen 2.833 N/A ARG 87.A NE ALA 33.A O no hydrogen 2.755 N/A ARG 87.A NH2 ALA 33.A O no hydrogen 2.894 N/A ARG 87.A NH2 PRO 56.A O no hydrogen 3.203 N/A GLU 88.A N LEU 29.A O no hydrogen 2.835 N/A LYS 89.A N GLU 86.A O no hydrogen 3.421 N/A LYS 89.A NZ GLU 86.A OE1 no hydrogen 3.219 N/A LYS 89.A NZ GLU 86.A OE2 no hydrogen 3.373 N/A PHE 91.A N GLY 27.A O no hydrogen 2.916 N/A VAL 92.A N ASN 107.A OD1 no hydrogen 3.006 N/A LEU 93.A N LEU 25.A O no hydrogen 2.760 N/A VAL 94.A N THR 105.A O no hydrogen 2.944 N/A ILE 95.A N ILE 23.A O no hydrogen 2.774 N/A VAL 96.A N GLN 103.A O no hydrogen 2.950 N/A ILE 97.A N ALA 21.A O no hydrogen 2.898 N/A GLN 98.A N THR 101.A O no hydrogen 2.947 N/A GLN 98.A NE2 GLN 103.A OE1 no hydrogen 3.100 N/A SER 99.A OG ASP 100.A OD2 no hydrogen 3.273 N/A TYR 102.A N PHE 114.A O no hydrogen 2.771 N/A GLN 103.A N VAL 96.A O no hydrogen 2.963 N/A ILE 104.A N VAL 112.A O no hydrogen 2.867 N/A THR 105.A N VAL 94.A O no hydrogen 2.967 N/A VAL 106.A N LYS 109.A O no hydrogen 2.929 N/A ASN 107.A N VAL 92.A O no hydrogen 2.881 N/A LYS 109.A N VAL 106.A O no hydrogen 2.917 N/A LYS 109.A NZ GLU 82.A OE1 no hydrogen 3.196 N/A LEU 111.A N ILE 104.A O no hydrogen 2.852 N/A VAL 112.A N ILE 104.A O no hydrogen 3.237 N/A PHE 114.A N TYR 102.A O no hydrogen 2.890 N/A GLN 116.A N ASP 100.A O no hydrogen 3.055 N/A GLN 116.A NE2 THR 101.A O no hydrogen 3.619 N/A ARG 117.A NH1 ASN 66.A OD1 no hydrogen 2.994 N/A ARG 117.A NH1 SER 67.A OG no hydrogen 3.091 N/A ARG 117.A NH1 GLU 76.A O no hydrogen 3.122 N/A ARG 117.A NH2 GLU 76.A O no hydrogen 2.749 N/A GLN 119.A NE2 GLN 116.A OE1 no hydrogen 2.880 N/A THR 122.A N VAL 41.A O no hydrogen 2.907 N/A THR 122.A OG1 VAL 41.A O no hydrogen 3.497 N/A ARG 123.A NE GLU 188.A OE2 no hydrogen 2.679 N/A ALA 124.A N LEU 11.A O no hydrogen 2.911 N/A SER 125.A N ASP 39.A O no hydrogen 2.788 N/A SER 125.A OG GLU 188.A OE1 no hydrogen 2.891 N/A LEU 126.A N PHE 9.A O no hydrogen 2.796 N/A SER 127.A N THR 37.A O no hydrogen 2.935 N/A ASP 129.A N PHE 35.A O no hydrogen 2.834 N/A LEU 130.A N GLY 128.A O no hydrogen 2.943 N/A VAL 131.A N THR 28.A O no hydrogen 2.894 N/A THR 133.A OG1 PRO 8.A O no hydrogen 2.676 N/A ARG 134.A N GLU 26.A O no hydrogen 2.941 N/A ARG 134.A NE GLU 26.A OE1 no hydrogen 3.094 N/A ARG 134.A NH2 GLU 26.A OE2 no hydrogen 3.062 N/A LEU 135.A N ILE 7.A O no hydrogen 2.911 N/A THR 136.A N VAL 24.A O no hydrogen 2.981 N/A TYR 138.A N SER 22.A O no hydrogen 2.793 N/A ASP 142.A N PRO 139.A O no hydrogen 3.224 N/A ARG 144.A NH1 THR 147.A OG1 no hydrogen 2.767 N/A THR 147.A N ARG 144.A O no hydrogen 2.873 N/A THR 147.A OG1 ARG 144.A O no hydrogen 2.498 N/A LEU 148.A N PRO 145.A O no hydrogen 2.954 N/A TYR 163.A OH LEU 130.A O no hydrogen 2.578 N/A LEU 165.A N VAL 284.A O no hydrogen 2.928 N/A ASN 166.A ND2 LYS 282.A O no hydrogen 2.906 N/A LEU 167.A N LYS 282.A O no hydrogen 2.673 N/A GLY 170.A N LEU 167.A O no hydrogen 2.920 N/A LEU 171.A N LEU 278.A O no hydrogen 2.895 N/A THR 172.A OG1 THR 175.A OG1 no hydrogen 3.170 N/A ARG 174.A N THR 254.A O no hydrogen 2.764 N/A THR 175.A N THR 254.A OG1 no hydrogen 2.819 N/A THR 175.A OG1 THR 172.A O no hydrogen 2.733 N/A LEU 176.A N GLN 298.A O no hydrogen 2.901 N/A LEU 177.A N ILE 252.A O no hydrogen 2.854 N/A THR 178.A N GLU 296.A O no hydrogen 2.986 N/A VAL 179.A N LEU 250.A O no hydrogen 2.829 N/A THR 180.A N HIS 294.A O no hydrogen 2.868 N/A THR 180.A OG1 HIS 294.A O no hydrogen 3.384 N/A GLY 181.A N PHE 248.A O no hydrogen 3.383 N/A THR 182.A N VAL 291.A O no hydrogen 2.882 N/A THR 184.A N HIS 289.A O no hydrogen 3.058 N/A THR 184.A OG1 HIS 289.A O no hydrogen 3.483 N/A ALA 187.A N THR 184.A O no hydrogen 3.111 N/A GLU 188.A N HIS 289.A ND1 no hydrogen 3.049 N/A PHE 190.A N VAL 211.A O no hydrogen 2.967 N/A ILE 191.A N PHE 287.A O no hydrogen 2.849 N/A VAL 192.A N PHE 209.A O no hydrogen 3.058 N/A ASN 193.A N HIS 285.A O no hydrogen 2.835 N/A LEU 194.A N LEU 207.A O no hydrogen 2.920 N/A VAL 195.A N TYR 283.A O no hydrogen 2.949 N/A TYR 196.A N ASN 204.A O no hydrogen 2.986 N/A SER 202.A OG ASP 197.A O no hydrogen 2.589 N/A SER 202.A OG ASP 197.A OD2 no hydrogen 3.371 N/A LYS 203.A NZ ASP 201.A O no hydrogen 2.514 N/A VAL 205.A N ARG 226.A O no hydrogen 2.929 N/A ALA 206.A N LEU 194.A O no hydrogen 2.822 N/A LEU 207.A N LEU 194.A O no hydrogen 3.479 N/A HIS 208.A N ASN 224.A O no hydrogen 2.826 N/A HIS 208.A ND1 ASN 193.A OD1 no hydrogen 2.850 N/A PHE 209.A N VAL 192.A O no hydrogen 2.910 N/A ASN 210.A N ALA 222.A O no hydrogen 2.817 N/A ASN 210.A ND2 HIS 208.A NE2 no hydrogen 3.190 N/A VAL 211.A N PHE 190.A O no hydrogen 2.916 N/A GLY 212.A N HIS 220.A O no hydrogen 2.792 N/A PHE 213.A N GLU 188.A O no hydrogen 2.949 N/A THR 214.A N LYS 218.A O no hydrogen 2.983 N/A SER 215.A N LYS 218.A O no hydrogen 3.382 N/A HIS 220.A N GLY 212.A O no hydrogen 2.887 N/A ALA 222.A N ASN 210.A O no hydrogen 2.942 N/A CYS 223.A N ILE 235.A O no hydrogen 2.979 N/A ASN 224.A N HIS 208.A O no hydrogen 3.077 N/A ASN 224.A ND2 GLY 232.A O no hydrogen 2.987 N/A ALA 225.A N ASN 224.A OD1 no hydrogen 2.763 N/A ARG 226.A N VAL 205.A O no hydrogen 2.834 N/A ARG 226.A NH1 ASP 201.A O no hydrogen 3.511 N/A ARG 226.A NH1 SER 202.A O no hydrogen 2.863 N/A MET 227.A N THR 230.A O no hydrogen 2.827 N/A ASN 228.A N ASN 204.A OD1 no hydrogen 2.842 N/A GLY 229.A N LYS 203.A O no hydrogen 2.783 N/A THR 230.A N MET 227.A O no hydrogen 3.053 N/A GLY 232.A N ASN 224.A OD1 no hydrogen 3.140 N/A GLY 232.A N ALA 225.A O no hydrogen 3.209 N/A ILE 235.A N CYS 223.A O no hydrogen 2.868 N/A VAL 237.A N ILE 221.A O no hydrogen 2.974 N/A ARG 244.A N ASP 216.A O no hydrogen 2.936 N/A ARG 244.A NE ALA 187.A O no hydrogen 2.932 N/A ARG 244.A NH1 ASP 216.A OD1 no hydrogen 3.220 N/A ARG 244.A NH2 ALA 187.A O no hydrogen 2.902 N/A GLY 245.A N PRO 183.A O no hydrogen 2.806 N/A LYS 246.A N GLN 243.A O no hydrogen 2.969 N/A PHE 248.A N GLY 181.A O no hydrogen 2.842 N/A THR 249.A N ASP 264.A OD1 no hydrogen 2.918 N/A LEU 250.A N VAL 179.A O no hydrogen 2.834 N/A GLN 251.A N LEU 262.A O no hydrogen 2.936 N/A ILE 252.A N LEU 177.A O no hydrogen 2.894 N/A LEU 253.A N GLN 260.A O no hydrogen 2.924 N/A THR 254.A N THR 175.A O no hydrogen 3.114 N/A THR 254.A OG1 THR 172.A O no hydrogen 2.707 N/A THR 254.A OG1 THR 175.A O no hydrogen 3.260 N/A ARG 255.A N ASP 258.A O no hydrogen 2.951 N/A ARG 255.A NH1 ASP 258.A OD1 no hydrogen 3.568 N/A ARG 255.A NH1 ASP 258.A OD2 no hydrogen 3.140 N/A PHE 259.A N PHE 271.A O no hydrogen 2.867 N/A GLN 260.A N LEU 253.A O no hydrogen 2.889 N/A GLN 260.A NE2 VAL 261.A O no hydrogen 3.265 N/A GLN 260.A NE2 THR 269.A O no hydrogen 3.191 N/A VAL 261.A N THR 269.A O no hydrogen 2.738 N/A LEU 262.A N GLN 251.A O no hydrogen 2.980 N/A VAL 263.A N GLN 266.A O no hydrogen 3.048 N/A ASP 264.A N THR 249.A O no hydrogen 2.829 N/A GLN 266.A N VAL 263.A O no hydrogen 3.032 N/A LEU 268.A N VAL 261.A O no hydrogen 2.749 N/A THR 269.A N VAL 261.A O no hydrogen 3.180 N/A GLN 270.A NE2 GLN 260.A OE1 no hydrogen 3.524 N/A PHE 271.A N PHE 259.A O no hydrogen 2.834 N/A TYR 273.A N ALA 257.A O no hydrogen 2.984 N/A TYR 273.A OH ARG 255.A O no hydrogen 3.045 N/A ARG 274.A NH1 ASN 224.A OD1 no hydrogen 3.043 N/A ARG 274.A NH1 SER 233.A O no hydrogen 3.045 N/A ARG 274.A NH2 SER 233.A O no hydrogen 2.859 N/A LEU 278.A N LYS 276.A O no hydrogen 3.267 N/A GLN 280.A N GLU 277.A O no hydrogen 2.930 N/A ILE 281.A N LEU 278.A O no hydrogen 3.160 N/A LYS 282.A N VAL 195.A O no hydrogen 2.981 N/A TYR 283.A N VAL 195.A O no hydrogen 3.189 N/A VAL 284.A N LEU 165.A O no hydrogen 2.937 N/A HIS 285.A N ASN 193.A O no hydrogen 2.856 N/A HIS 285.A NE2 ASP 129.A OD1 no hydrogen 2.579 N/A MET 286.A N TYR 163.A O no hydrogen 2.939 N/A PHE 287.A N ILE 191.A O no hydrogen 2.954 N/A HIS 289.A N PHE 189.A O no hydrogen 2.929 N/A HIS 289.A NE2 LEU 126.A O no hydrogen 2.769 N/A VAL 291.A N THR 182.A O no hydrogen 2.909 N/A GLN 292.A NE2 GLY 1.A O no hydrogen 3.348 N/A THR 293.A OG1 ALA 162.A O no hydrogen 2.554 N/A HIS 294.A N THR 180.A O no hydrogen 3.071 N/A GLU 296.A N THR 178.A O no hydrogen 2.904 N/A GLN 298.A N LEU 176.A O no hydrogen 2.911 N/A