Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2wtd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 8.A N PRO 4.A O no hydrogen 3.065 N/A ASP 9.A N LYS 5.A O no hydrogen 2.863 N/A GLU 10.A N LEU 7.A O no hydrogen 2.981 N/A TYR 11.A N LEU 7.A O no hydrogen 3.023 N/A ILE 12.A N PHE 25.A O no hydrogen 2.866 N/A SER 14.A N LEU 23.A O no hydrogen 2.757 N/A THR 16.A OG1 GLU 20.A OE1 no hydrogen 2.945 N/A LEU 17.A N VAL 21.A O no hydrogen 2.763 N/A GLY 18.A N VAL 21.A O no hydrogen 3.506 N/A GLU 20.A N ILE 37.A O no hydrogen 3.393 N/A VAL 21.A N GLY 18.A O no hydrogen 3.404 N/A LYS 22.A N ILE 35.A O no hydrogen 2.954 N/A LYS 22.A NZ SER 14.A O no hydrogen 3.327 N/A LYS 22.A NZ THR 16.A OG1 no hydrogen 3.020 N/A LEU 23.A N LYS 15.A O no hydrogen 2.794 N/A ALA 24.A N VAL 33.A O no hydrogen 2.970 N/A PHE 25.A N ILE 12.A O no hydrogen 2.832 N/A GLU 26.A N LYS 31.A O no hydrogen 2.890 N/A ARG 27.A N GLU 10.A O no hydrogen 2.812 N/A ARG 27.A NE ARG 8.A O no hydrogen 2.820 N/A ARG 27.A NH2 ARG 8.A O no hydrogen 2.885 N/A THR 29.A N GLU 26.A O no hydrogen 3.272 N/A THR 29.A OG1 GLU 26.A OE1 no hydrogen 3.062 N/A CYS 30.A N GLU 26.A O no hydrogen 2.716 N/A CYS 30.A SG ARG 27.A O no hydrogen 4.016 N/A LYS 31.A N THR 29.A OG1 no hydrogen 3.145 N/A VAL 33.A N ALA 24.A O no hydrogen 2.713 N/A ALA 34.A N LEU 76.A O no hydrogen 2.894 N/A ILE 35.A N LYS 22.A O no hydrogen 2.859 N/A LYS 36.A N ILE 74.A O no hydrogen 2.860 N/A LYS 36.A NZ GLU 48.A OE1 no hydrogen 2.934 N/A ILE 37.A N GLU 20.A O no hydrogen 2.816 N/A ILE 38.A N TYR 72.A O no hydrogen 2.863 N/A LYS 40.A NZ ASP 68.A OD2 no hydrogen 2.646 N/A LYS 40.A NZ ALA 69.A O no hydrogen 2.738 N/A VAL 45.A N PRO 41.A O no hydrogen 3.462 N/A GLU 46.A N ALA 42.A O no hydrogen 3.003 N/A THR 47.A N LEU 43.A O no hydrogen 3.084 N/A THR 47.A OG1 ASN 44.A O no hydrogen 3.249 N/A GLU 48.A N ASN 44.A O no hydrogen 3.006 N/A ILE 49.A N VAL 45.A O no hydrogen 2.911 N/A GLU 50.A N GLU 46.A O no hydrogen 3.122 N/A ILE 51.A N THR 47.A O no hydrogen 2.728 N/A LEU 52.A N GLU 48.A O no hydrogen 2.902 N/A LYS 53.A N ILE 49.A O no hydrogen 2.849 N/A LYS 54.A N ILE 51.A O no hydrogen 3.011 N/A LEU 55.A N ILE 51.A O no hydrogen 3.071 N/A ASN 56.A N TYR 112.A OH no hydrogen 2.812 N/A CYS 59.A N HIS 57.A ND1 no hydrogen 2.998 N/A CYS 59.A SG GLN 105.A OE1 no hydrogen 3.864 N/A ILE 60.A N HIS 57.A O no hydrogen 3.032 N/A ILE 61.A N ILE 141.A O no hydrogen 3.123 N/A LYS 62.A N GLU 77.A OE2 no hydrogen 3.021 N/A LYS 62.A NZ ASN 56.A OD1 no hydrogen 2.884 N/A LYS 64.A N VAL 75.A O no hydrogen 2.708 N/A ASN 65.A ND2 GLU 10.A OE1 no hydrogen 3.376 N/A ASN 65.A ND2 TYR 11.A OH no hydrogen 3.125 N/A PHE 66.A N ASN 65.A OD1 no hydrogen 2.703 N/A PHE 67.A N TYR 73.A O no hydrogen 2.750 N/A ALA 69.A N ASP 71.A O no hydrogen 2.883 N/A TYR 72.A N ILE 38.A O no hydrogen 2.744 N/A TYR 73.A N PHE 67.A O no hydrogen 2.766 N/A ILE 74.A N LYS 36.A O no hydrogen 3.004 N/A VAL 75.A N ASN 65.A O no hydrogen 2.851 N/A LEU 76.A N ALA 34.A O no hydrogen 2.664 N/A GLU 77.A N LYS 62.A O no hydrogen 3.498 N/A GLY 82.A N MET 79.A O no hydrogen 3.144 N/A LEU 84.A N VAL 128.A O no hydrogen 2.857 N/A PHE 85.A N PRO 125.A O no hydrogen 3.124 N/A LYS 87.A N LEU 84.A O no hydrogen 2.607 N/A VAL 88.A N PHE 85.A O no hydrogen 2.888 N/A VAL 89.A N PHE 85.A O no hydrogen 3.030 N/A LYS 92.A N VAL 89.A O no hydrogen 3.397 N/A LYS 92.A NZ ASP 86.A O no hydrogen 3.427 N/A LEU 94.A N CYS 193.A O no hydrogen 3.435 N/A LYS 95.A NZ GLU 135.A OE2 no hydrogen 3.242 N/A THR 98.A N LYS 95.A O no hydrogen 2.770 N/A THR 98.A OG1 GLU 135.A OE1 no hydrogen 3.194 N/A CYS 99.A N LYS 95.A O no hydrogen 3.142 N/A CYS 99.A SG LEU 94.A O no hydrogen 3.724 N/A CYS 99.A SG LYS 95.A O no hydrogen 3.850 N/A LYS 100.A N GLU 96.A O no hydrogen 3.031 N/A LYS 100.A NZ TRP 258.A O no hydrogen 2.974 N/A LYS 100.A NZ ASP 261.A OD2 no hydrogen 2.754 N/A LEU 101.A N ALA 97.A O no hydrogen 3.198 N/A TYR 102.A N THR 98.A O no hydrogen 2.987 N/A TYR 102.A OH GLU 135.A O no hydrogen 2.723 N/A PHE 103.A N CYS 99.A O no hydrogen 2.728 N/A TYR 104.A N LYS 100.A O no hydrogen 2.821 N/A GLN 105.A N LEU 101.A O no hydrogen 3.423 N/A GLN 105.A NE2 LEU 101.A O no hydrogen 3.221 N/A GLN 105.A NE2 CYS 137.A O no hydrogen 3.173 N/A MET 106.A N TYR 102.A O no hydrogen 2.965 N/A LEU 107.A N PHE 103.A O no hydrogen 2.725 N/A LEU 108.A N TYR 104.A O no hydrogen 3.011 N/A ALA 109.A N GLN 105.A O no hydrogen 2.914 N/A VAL 110.A N MET 106.A O no hydrogen 2.890 N/A GLN 111.A N LEU 107.A O no hydrogen 2.759 N/A TYR 112.A N LEU 108.A O no hydrogen 2.827 N/A LEU 113.A N ALA 109.A O no hydrogen 2.854 N/A HIS 114.A N VAL 110.A O no hydrogen 2.952 N/A HIS 114.A NE2 ASP 182.A OD2 no hydrogen 3.082 N/A GLU 115.A N GLN 111.A O no hydrogen 2.830 N/A ASN 116.A N TYR 112.A O no hydrogen 3.129 N/A ASN 116.A N LEU 113.A O no hydrogen 3.092 N/A ASN 116.A ND2 TYR 112.A O no hydrogen 2.889 N/A GLY 117.A N HIS 114.A O no hydrogen 2.881 N/A ILE 118.A N LEU 113.A O no hydrogen 2.920 N/A ILE 119.A N LYS 148.A O no hydrogen 3.028 N/A HIS 120.A N ASP 182.A OD2 no hydrogen 2.878 N/A HIS 120.A NE2 THR 142.A O no hydrogen 2.959 N/A ARG 121.A N ASP 182.A OD1 no hydrogen 2.899 N/A ASP 122.A N HIS 120.A ND1 no hydrogen 2.974 N/A ASN 127.A N LYS 124.A O no hydrogen 3.026 N/A ASN 127.A ND2 ASP 122.A O no hydrogen 2.703 N/A ASN 127.A ND2 ASP 122.A OD2 no hydrogen 3.459 N/A VAL 128.A N PRO 125.A O no hydrogen 3.313 N/A LEU 129.A N LYS 140.A O no hydrogen 2.980 N/A LEU 130.A N GLY 82.A O no hydrogen 2.814 N/A SER 131.A N LEU 138.A O no hydrogen 2.846 N/A SER 131.A OG LEU 138.A O no hydrogen 3.343 N/A GLU 134.A N SER 132.A OG no hydrogen 3.285 N/A CYS 137.A SG TYR 102.A OH no hydrogen 3.717 N/A CYS 137.A SG GLU 134.A O no hydrogen 3.671 N/A CYS 137.A SG LEU 138.A O no hydrogen 3.723 N/A LEU 138.A N SER 131.A OG no hydrogen 3.133 N/A ILE 139.A N GLN 105.A OE1 no hydrogen 2.761 N/A LYS 140.A N LEU 129.A O no hydrogen 2.923 N/A LYS 140.A NZ PRO 58.A O no hydrogen 2.979 N/A LYS 140.A NZ GLU 275.A OE2 no hydrogen 3.227 N/A ILE 141.A N CYS 59.A O no hydrogen 2.868 N/A THR 142.A N ASN 127.A O no hydrogen 2.835 N/A GLY 145.A N ASP 143.A OD1 no hydrogen 3.435 N/A SER 147.A N PHE 144.A O no hydrogen 3.256 N/A SER 147.A OG HIS 120.A O no hydrogen 3.526 N/A SER 147.A OG PHE 144.A O no hydrogen 3.205 N/A LYS 148.A N ILE 119.A O no hydrogen 2.930 N/A LEU 150.A N GLY 117.A O no hydrogen 2.996 N/A ARG 155.A N THR 151.A O no hydrogen 3.052 N/A THR 156.A N SER 152.A O no hydrogen 2.960 N/A THR 156.A OG1 SER 152.A O no hydrogen 3.121 N/A LEU 157.A N LEU 153.A O no hydrogen 2.724 N/A LEU 157.A N MET 154.A O no hydrogen 3.180 N/A CYS 158.A N ARG 155.A O no hydrogen 2.936 N/A CYS 158.A SG MET 154.A O no hydrogen 3.656 N/A GLY 159.A N THR 156.A O no hydrogen 3.512 N/A TYR 163.A N PRO 161.A O no hydrogen 2.341 N/A LEU 164.A N PRO 161.A O no hydrogen 3.141 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.638 N/A VAL 168.A N ALA 165.A O no hydrogen 3.224 N/A VAL 170.A N PRO 166.A O no hydrogen 3.018 N/A SER 171.A N GLU 167.A O no hydrogen 3.128 N/A SER 171.A N VAL 168.A O no hydrogen 2.908 N/A SER 171.A OG VAL 168.A O no hydrogen 2.431 N/A VAL 172.A N LEU 169.A O no hydrogen 3.389 N/A THR 174.A N SER 171.A O no hydrogen 3.329 N/A ALA 175.A N SER 171.A O no hydrogen 2.951 N/A TYR 177.A N THR 174.A O no hydrogen 3.248 N/A ALA 180.A N TYR 177.A O no hydrogen 2.978 N/A VAL 181.A N ASN 178.A O no hydrogen 3.034 N/A ASP 182.A N ARG 179.A O no hydrogen 3.149 N/A CYS 183.A SG PHE 248.A O no hydrogen 3.490 N/A TRP 184.A N ALA 180.A O no hydrogen 2.950 N/A SER 185.A N VAL 181.A O no hydrogen 3.052 N/A SER 185.A OG VAL 181.A O no hydrogen 3.039 N/A LEU 186.A N ASP 182.A O no hydrogen 2.875 N/A GLY 187.A N CYS 183.A O no hydrogen 3.000 N/A VAL 188.A N TRP 184.A O no hydrogen 2.988 N/A ILE 189.A N SER 185.A O no hydrogen 2.890 N/A LEU 190.A N LEU 186.A O no hydrogen 2.894 N/A PHE 191.A N GLY 187.A O no hydrogen 3.078 N/A ILE 192.A N VAL 188.A O no hydrogen 3.099 N/A CYS 193.A N ILE 189.A O no hydrogen 2.926 N/A CYS 193.A SG ILE 189.A O no hydrogen 3.324 N/A LEU 194.A N LEU 190.A O no hydrogen 2.989 N/A SER 195.A N PHE 191.A O no hydrogen 2.905 N/A SER 195.A OG PHE 191.A O no hydrogen 3.076 N/A GLY 196.A N ILE 192.A O no hydrogen 2.724 N/A TYR 197.A N SER 195.A OG no hydrogen 2.851 N/A TYR 197.A OH ASN 219.A O no hydrogen 2.857 N/A ASP 211.A N SER 208.A OG no hydrogen 2.957 N/A GLN 212.A N SER 208.A O no hydrogen 2.924 N/A GLN 212.A NE2 SER 201.A O no hydrogen 3.045 N/A GLN 212.A NE2 VAL 207.A O no hydrogen 3.037 N/A GLN 212.A NE2 SER 208.A O no hydrogen 3.265 N/A ILE 213.A N LEU 209.A O no hydrogen 3.070 N/A THR 214.A N LYS 210.A O no hydrogen 2.969 N/A THR 214.A OG1 LYS 210.A O no hydrogen 2.808 N/A THR 214.A OG1 ASP 211.A O no hydrogen 3.334 N/A SER 215.A N ASP 211.A O no hydrogen 2.996 N/A SER 215.A OG ASP 211.A O no hydrogen 3.199 N/A SER 215.A OG GLN 212.A O no hydrogen 2.862 N/A GLY 216.A N ILE 213.A O no hydrogen 3.221 N/A LYS 217.A N SER 215.A OG no hydrogen 2.933 N/A ASN 219.A N PRO 199.A O no hydrogen 2.882 N/A ILE 221.A N TYR 197.A OH no hydrogen 2.834 N/A VAL 224.A N ILE 221.A O no hydrogen 2.989 N/A TRP 225.A N ILE 221.A O no hydrogen 3.259 N/A TRP 225.A NE1 TYR 197.A OH no hydrogen 2.822 N/A ALA 226.A N PRO 222.A O no hydrogen 2.931 N/A VAL 228.A N TRP 225.A O no hydrogen 2.825 N/A SER 229.A N GLU 96.A OE1 no hydrogen 3.019 N/A ALA 232.A N SER 229.A OG no hydrogen 3.018 N/A LEU 233.A N SER 229.A O no hydrogen 3.507 N/A ASP 234.A N GLU 230.A O no hydrogen 2.853 N/A LEU 235.A N LYS 231.A O no hydrogen 3.011 N/A VAL 236.A N ALA 232.A O no hydrogen 3.073 N/A LYS 237.A N LEU 233.A O no hydrogen 3.018 N/A LYS 238.A N ASP 234.A O no hydrogen 3.158 N/A LYS 238.A N LEU 235.A O no hydrogen 3.162 N/A LYS 238.A NZ ASP 234.A OD2 no hydrogen 2.696 N/A LEU 239.A N LEU 235.A O no hydrogen 3.169 N/A LEU 239.A N VAL 236.A O no hydrogen 2.938 N/A LEU 240.A N VAL 236.A O no hydrogen 2.912 N/A LYS 245.A N ASP 243.A OD1 no hydrogen 3.045 N/A LYS 245.A NZ GLY 173.A O no hydrogen 3.078 N/A ALA 246.A N ASP 243.A O no hydrogen 3.088 N/A ARG 247.A N PRO 244.A O no hydrogen 3.345 N/A ARG 247.A NE VAL 241.A O no hydrogen 2.726 N/A ARG 247.A NH1 VAL 241.A O no hydrogen 3.030 N/A ARG 247.A NH1 VAL 242.A O no hydrogen 3.296 N/A ARG 247.A NH2 ALA 180.A O no hydrogen 2.805 N/A PHE 248.A N LYS 238.A O no hydrogen 3.120 N/A THR 249.A N GLU 252.A OE1 no hydrogen 3.122 N/A THR 249.A OG1 GLU 251.A OE1 no hydrogen 3.022 N/A THR 249.A OG1 GLU 252.A OE1 no hydrogen 3.523 N/A THR 250.A OG1 GLU 251.A OE2 no hydrogen 3.276 N/A GLU 252.A N THR 249.A OG1 no hydrogen 3.189 N/A ALA 253.A N THR 249.A O no hydrogen 2.965 N/A LEU 254.A N THR 250.A O no hydrogen 2.782 N/A ARG 255.A N GLU 251.A O no hydrogen 2.952 N/A HIS 256.A N ALA 253.A O no hydrogen 2.995 N/A HIS 256.A NE2 ASP 234.A OD2 no hydrogen 2.849 N/A TRP 258.A N HIS 256.A ND1 no hydrogen 2.834 N/A TRP 258.A NE1 GLU 96.A OE2 no hydrogen 2.798 N/A LEU 259.A N HIS 256.A O no hydrogen 2.795 N/A GLN 260.A N PRO 257.A O no hydrogen 3.098 N/A GLN 260.A NE2 LEU 254.A O no hydrogen 2.758 N/A GLN 260.A NE2 HIS 256.A O no hydrogen 2.983 N/A MET 264.A N ASP 261.A OD1 no hydrogen 3.095 N/A LYS 265.A N ASP 261.A O no hydrogen 3.152 N/A ARG 266.A N GLU 262.A O no hydrogen 3.078 N/A ARG 266.A NH2 ASP 263.A OD1 no hydrogen 2.846 N/A LYS 267.A N ASP 263.A O no hydrogen 3.017 N/A PHE 268.A N MET 264.A O no hydrogen 3.082 N/A GLN 269.A N LYS 265.A O no hydrogen 2.886 N/A ASP 270.A N ARG 266.A O no hydrogen 2.710 N/A LEU 271.A N LYS 267.A O no hydrogen 2.895 N/A LEU 272.A N PHE 268.A O no hydrogen 2.819 N/A SER 273.A N GLN 269.A O no hydrogen 3.282 N/A SER 273.A OG GLN 269.A O no hydrogen 3.462 N/A SER 273.A OG ASP 270.A O no hydrogen 3.287 N/A GLU 274.A N ASP 270.A O no hydrogen 3.185 N/A GLU 275.A N LEU 271.A O no hydrogen 3.276 N/A GLU 275.A N LEU 272.A O no hydrogen 2.865 N/A ASN 276.A N LEU 272.A O no hydrogen 3.111 N/A GLU 277.A N SER 273.A O no hydrogen 3.021 N/A SER 278.A OG GLU 275.A O no hydrogen 3.322 N/A THR 279.A N ASN 276.A O no hydrogen 2.851 N/A THR 279.A OG1 ASN 276.A O no hydrogen 3.502 N/A ALA 280.A N ASN 276.A O no hydrogen 2.952 N/A GLN 283.A NE2 LEU 281.A O no hydrogen 3.314 N/A