Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2wxv_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 7.A N TYR 3.A O no hydrogen 2.956 N/A HIS 8.A N HIS 4.A O no hydrogen 3.171 N/A THR 9.A N GLU 5.A O no hydrogen 2.874 N/A THR 9.A OG1 GLU 5.A O no hydrogen 3.155 N/A TYR 10.A N ASP 6.A O no hydrogen 2.979 N/A LEU 11.A N ILE 7.A O no hydrogen 2.835 N/A ARG 12.A N HIS 8.A O no hydrogen 2.976 N/A ARG 12.A NH1 THR 205.A O no hydrogen 3.000 N/A GLU 13.A N THR 9.A O no hydrogen 3.278 N/A GLU 13.A N TYR 10.A O no hydrogen 3.235 N/A MET 14.A N TYR 10.A O no hydrogen 3.034 N/A GLU 15.A N LEU 11.A O no hydrogen 2.940 N/A CYS 18.A N MET 14.A O no hydrogen 2.788 N/A LYS 19.A NZ LEU 173.A O no hydrogen 3.541 N/A LYS 21.A N SER 69.A OG no hydrogen 2.892 N/A TYR 24.A N LYS 21.A O no hydrogen 3.376 N/A TYR 24.A OH ASP 65.A OD1 no hydrogen 2.734 N/A LYS 26.A NZ GLY 23.A O no hydrogen 3.506 N/A GLN 28.A N MET 25.A O no hydrogen 3.206 N/A GLN 28.A NE2 LEU 68.A O no hydrogen 3.254 N/A GLN 28.A NE2 MET 71.A O no hydrogen 3.681 N/A ARG 36.A N THR 32.A O no hydrogen 3.098 N/A ARG 36.A NE ASP 65.A OD1 no hydrogen 2.900 N/A ARG 36.A NH1 LEU 166.A O no hydrogen 2.886 N/A ARG 36.A NH2 ASP 65.A OD1 no hydrogen 3.477 N/A ARG 36.A NH2 ASP 65.A OD2 no hydrogen 2.821 N/A ARG 36.A NH2 LEU 166.A O no hydrogen 3.306 N/A ALA 37.A N ASN 33.A O no hydrogen 2.946 N/A ILE 38.A N SER 34.A O no hydrogen 2.904 N/A LEU 39.A N MET 35.A O no hydrogen 2.942 N/A VAL 40.A N ARG 36.A O no hydrogen 2.810 N/A ASP 41.A N ALA 37.A O no hydrogen 2.991 N/A TRP 42.A N ILE 38.A O no hydrogen 3.083 N/A LEU 43.A N LEU 39.A O no hydrogen 2.914 N/A VAL 44.A N VAL 40.A O no hydrogen 2.932 N/A GLU 45.A N ASP 41.A O no hydrogen 3.279 N/A VAL 46.A N TRP 42.A O no hydrogen 3.050 N/A GLY 47.A N LEU 43.A O no hydrogen 2.872 N/A GLU 48.A N VAL 44.A O no hydrogen 3.068 N/A GLU 49.A N GLU 45.A O no hydrogen 2.929 N/A TYR 50.A N VAL 46.A O no hydrogen 3.063 N/A TYR 50.A OH GLU 102.A OE2 no hydrogen 3.050 N/A LYS 51.A NZ GLU 48.A O no hydrogen 3.507 N/A LEU 52.A N GLY 47.A O no hydrogen 2.869 N/A GLN 53.A N GLU 94.A OE2 no hydrogen 2.712 N/A THR 56.A OG1 GLU 94.A OE2 no hydrogen 2.708 N/A HIS 58.A N ASN 54.A O no hydrogen 3.089 N/A LEU 59.A N GLU 55.A O no hydrogen 2.968 N/A ALA 60.A N THR 56.A O no hydrogen 3.044 N/A VAL 61.A N LEU 57.A O no hydrogen 3.275 N/A ASN 62.A N HIS 58.A O no hydrogen 3.223 N/A ASN 62.A ND2 CYS 18.A O no hydrogen 3.626 N/A TYR 63.A N LEU 59.A O no hydrogen 2.862 N/A TYR 63.A OH LEU 131.A O no hydrogen 2.563 N/A ILE 64.A N ALA 60.A O no hydrogen 2.930 N/A ASP 65.A N VAL 61.A O no hydrogen 2.970 N/A ARG 66.A N ASN 62.A O no hydrogen 3.100 N/A ARG 66.A NH1 ASN 62.A OD1 no hydrogen 2.739 N/A ARG 66.A NH1 ASP 130.A O no hydrogen 3.262 N/A ARG 66.A NH2 ASP 130.A O no hydrogen 2.796 N/A PHE 67.A N TYR 63.A O no hydrogen 2.913 N/A LEU 68.A N ILE 64.A O no hydrogen 2.901 N/A SER 69.A N ASP 65.A O no hydrogen 3.104 N/A SER 69.A N ARG 66.A O no hydrogen 3.075 N/A SER 69.A OG ASP 65.A O no hydrogen 2.731 N/A SER 70.A N PHE 67.A O no hydrogen 3.303 N/A MET 71.A N PHE 67.A O no hydrogen 2.974 N/A VAL 73.A N GLN 28.A OE1 no hydrogen 2.608 N/A ARG 75.A N ASP 30.A OD2 no hydrogen 2.913 N/A LYS 77.A N LEU 74.A O no hydrogen 2.728 N/A LEU 78.A N LEU 74.A O no hydrogen 3.164 N/A LEU 78.A N ARG 75.A O no hydrogen 3.239 N/A LEU 80.A N TYR 111.A OH no hydrogen 3.256 N/A VAL 81.A N LYS 77.A O no hydrogen 3.086 N/A GLY 82.A N LEU 78.A O no hydrogen 3.038 N/A THR 83.A N GLN 79.A O no hydrogen 2.727 N/A THR 83.A OG1 GLN 79.A O no hydrogen 2.927 N/A ALA 84.A N LEU 80.A O no hydrogen 2.973 N/A ALA 85.A N VAL 81.A O no hydrogen 2.977 N/A MET 86.A N GLY 82.A O no hydrogen 3.072 N/A LEU 87.A N THR 83.A O no hydrogen 3.030 N/A LEU 88.A N ALA 84.A O no hydrogen 3.014 N/A ALA 89.A N ALA 85.A O no hydrogen 3.052 N/A SER 90.A N MET 86.A O no hydrogen 2.780 N/A SER 90.A OG MET 86.A O no hydrogen 2.856 N/A LYS 91.A N LEU 87.A O no hydrogen 3.063 N/A LYS 91.A NZ GLU 120.A OE1 no hydrogen 3.548 N/A LYS 91.A NZ GLU 120.A OE2 no hydrogen 2.823 N/A PHE 92.A N LEU 88.A O no hydrogen 2.906 N/A GLU 93.A N ALA 89.A O no hydrogen 3.014 N/A GLU 94.A N SER 90.A O no hydrogen 2.765 N/A GLU 102.A N GLU 99.A O no hydrogen 2.939 N/A VAL 104.A N VAL 100.A O no hydrogen 2.867 N/A TYR 105.A N ALA 101.A O no hydrogen 2.973 N/A ILE 106.A N GLU 102.A O no hydrogen 2.986 N/A THR 107.A N VAL 104.A O no hydrogen 3.327 N/A THR 107.A OG1 VAL 104.A O no hydrogen 2.598 N/A ASP 108.A N TYR 105.A O no hydrogen 2.933 N/A THR 110.A N THR 107.A O no hydrogen 3.349 N/A THR 110.A OG1 THR 107.A O no hydrogen 2.697 N/A TYR 111.A OH GLY 76.A O no hydrogen 2.683 N/A THR 112.A N GLN 115.A OE1 no hydrogen 2.909 N/A GLN 115.A N THR 112.A OG1 no hydrogen 3.056 N/A VAL 116.A N THR 112.A O no hydrogen 3.007 N/A LEU 117.A N LYS 113.A O no hydrogen 2.972 N/A ARG 118.A N LYS 114.A O no hydrogen 2.957 N/A MET 119.A N GLN 115.A O no hydrogen 2.938 N/A GLU 120.A N VAL 116.A O no hydrogen 2.966 N/A HIS 121.A N LEU 117.A O no hydrogen 3.138 N/A LEU 122.A N ARG 118.A O no hydrogen 3.096 N/A VAL 123.A N MET 119.A O no hydrogen 2.831 N/A LEU 124.A N GLU 120.A O no hydrogen 3.003 N/A LYS 125.A N HIS 121.A O no hydrogen 2.947 N/A VAL 126.A N LEU 122.A O no hydrogen 2.888 N/A LEU 127.A N VAL 123.A O no hydrogen 2.758 N/A THR 128.A N LYS 125.A O no hydrogen 3.013 N/A THR 128.A OG1 LEU 127.A O no hydrogen 2.490 N/A THR 128.A OG1 ASP 130.A OD2 no hydrogen 2.581 N/A PHE 129.A N LEU 124.A O no hydrogen 2.968 N/A ASP 130.A N LEU 127.A O no hydrogen 3.018 N/A ALA 133.A N LEU 131.A O no hydrogen 3.028 N/A THR 135.A OG1 GLU 55.A OE1 no hydrogen 2.899 N/A THR 135.A OG1 GLU 55.A OE2 no hydrogen 3.138 N/A ASN 137.A ND2 GLU 55.A OE1 no hydrogen 3.519 N/A GLN 138.A N THR 135.A O no hydrogen 2.891 N/A GLN 138.A N THR 135.A OG1 no hydrogen 3.058 N/A GLN 138.A NE2 GLU 55.A OE2 no hydrogen 2.741 N/A GLN 138.A NE2 ALA 133.A O no hydrogen 2.920 N/A GLN 138.A NE2 THR 135.A OG1 no hydrogen 3.422 N/A PHE 139.A N THR 135.A O no hydrogen 3.251 N/A LEU 140.A N VAL 136.A O no hydrogen 2.967 N/A THR 141.A N ASN 137.A O no hydrogen 3.121 N/A THR 141.A OG1 ASN 137.A O no hydrogen 3.240 N/A GLN 142.A N GLN 138.A O no hydrogen 3.321 N/A TYR 143.A N PHE 139.A O no hydrogen 2.895 N/A TYR 143.A OH SER 178.A O no hydrogen 2.838 N/A PHE 144.A N LEU 140.A O no hydrogen 2.700 N/A HIS 146.A N TYR 143.A O no hydrogen 2.751 N/A HIS 146.A ND1 SER 200.A OG no hydrogen 3.112 N/A GLN 147.A N PHE 144.A O no hydrogen 2.912 N/A GLN 147.A NE2 PHE 144.A O no hydrogen 3.600 N/A ASN 151.A N GLN 147.A OE1 no hydrogen 3.030 N/A VAL 154.A N ASN 151.A OD1 no hydrogen 2.891 N/A GLU 155.A N ASN 151.A O no hydrogen 3.226 N/A SER 156.A N CYS 152.A O no hydrogen 3.145 N/A SER 156.A OG CYS 152.A O no hydrogen 3.223 N/A SER 156.A OG TYR 243.A O no hydrogen 3.365 N/A LEU 157.A N LYS 153.A O no hydrogen 3.055 N/A ALA 158.A N VAL 154.A O no hydrogen 2.937 N/A MET 159.A N GLU 155.A O no hydrogen 3.013 N/A PHE 160.A N SER 156.A O no hydrogen 2.976 N/A LEU 161.A N LEU 157.A O no hydrogen 2.978 N/A GLY 162.A N ALA 158.A O no hydrogen 2.882 N/A GLU 163.A N MET 159.A O no hydrogen 2.868 N/A LEU 164.A N PHE 160.A O no hydrogen 3.024 N/A SER 165.A N LEU 161.A O no hydrogen 3.331 N/A SER 165.A OG GLY 162.A O no hydrogen 2.666 N/A LEU 166.A N GLU 163.A O no hydrogen 3.262 N/A ILE 167.A N LEU 164.A O no hydrogen 3.002 N/A TYR 172.A N ASP 168.A O no hydrogen 3.400 N/A TYR 172.A OH THR 222.A OG1 no hydrogen 2.645 N/A LEU 173.A N ALA 169.A O no hydrogen 2.943 N/A TYR 175.A N TYR 172.A O no hydrogen 3.019 N/A TYR 175.A OH ASP 218.A OD2 no hydrogen 2.696 N/A SER 178.A N GLU 15.A OE1 no hydrogen 2.935 N/A SER 178.A OG GLU 15.A OE2 no hydrogen 2.984 N/A SER 178.A OG TYR 207.A OH no hydrogen 2.436 N/A VAL 179.A N LEU 176.A O no hydrogen 3.012 N/A ILE 180.A N LEU 176.A O no hydrogen 3.039 N/A ALA 181.A N PRO 177.A O no hydrogen 2.991 N/A GLY 182.A N SER 178.A O no hydrogen 3.097 N/A ALA 183.A N VAL 179.A O no hydrogen 3.004 N/A ALA 184.A N ILE 180.A O no hydrogen 2.817 N/A PHE 185.A N ALA 181.A O no hydrogen 2.795 N/A HIS 186.A N GLY 182.A O no hydrogen 3.056 N/A LEU 187.A N ALA 183.A O no hydrogen 2.872 N/A ALA 188.A N ALA 184.A O no hydrogen 3.052 N/A LEU 189.A N PHE 185.A O no hydrogen 2.899 N/A TYR 190.A N HIS 186.A O no hydrogen 2.883 N/A THR 191.A N LEU 187.A O no hydrogen 3.010 N/A THR 191.A OG1 LEU 187.A O no hydrogen 3.068 N/A VAL 192.A N ALA 188.A O no hydrogen 2.989 N/A THR 193.A N LEU 189.A O no hydrogen 3.032 N/A THR 193.A OG1 LEU 189.A O no hydrogen 2.624 N/A THR 193.A OG1 GLN 195.A OE1 no hydrogen 3.048 N/A GLY 194.A N TYR 190.A O no hydrogen 3.017 N/A GLN 195.A N THR 193.A OG1 no hydrogen 3.176 N/A SER 196.A OG HIS 186.A NE2 no hydrogen 3.286 N/A TRP 197.A NE1 TYR 207.A O no hydrogen 2.932 N/A SER 200.A OG HIS 146.A ND1 no hydrogen 3.112 N/A LEU 201.A N PRO 198.A O no hydrogen 3.054 N/A ILE 202.A N PRO 198.A O no hydrogen 3.181 N/A ARG 203.A N GLU 199.A O no hydrogen 3.056 N/A LYS 204.A N SER 200.A O no hydrogen 3.141 N/A THR 205.A N LEU 201.A O no hydrogen 2.830 N/A THR 205.A OG1 LEU 201.A O no hydrogen 2.587 N/A GLY 206.A N ILE 202.A O no hydrogen 2.877 N/A TYR 207.A N THR 205.A OG1 no hydrogen 3.016 N/A TYR 207.A OH SER 178.A OG no hydrogen 2.436 N/A THR 208.A N SER 211.A OG no hydrogen 2.659 N/A THR 208.A OG1 SER 211.A OG no hydrogen 3.085 N/A SER 211.A N THR 208.A OG1 no hydrogen 2.851 N/A SER 211.A OG THR 208.A O no hydrogen 2.727 N/A SER 211.A OG THR 208.A OG1 no hydrogen 3.085 N/A LEU 212.A N THR 208.A O no hydrogen 3.056 N/A LYS 213.A N GLU 210.A O no hydrogen 2.950 N/A LEU 216.A N LEU 212.A O no hydrogen 2.835 N/A MET 217.A N LYS 213.A O no hydrogen 2.816 N/A ASP 218.A N PRO 214.A O no hydrogen 3.364 N/A LEU 219.A N CYS 215.A O no hydrogen 2.829 N/A HIS 220.A N LEU 216.A O no hydrogen 2.785 N/A HIS 220.A NE2 PRO 252.A O no hydrogen 3.104 N/A GLN 221.A N MET 217.A O no hydrogen 3.042 N/A THR 222.A N ASP 218.A O no hydrogen 2.947 N/A THR 222.A OG1 TYR 172.A OH no hydrogen 2.645 N/A THR 222.A OG1 ASP 218.A O no hydrogen 2.968 N/A TYR 223.A N LEU 219.A O no hydrogen 2.857 N/A LEU 224.A N HIS 220.A O no hydrogen 2.908 N/A LYS 225.A N GLN 221.A O no hydrogen 2.956 N/A LYS 225.A NZ GLN 221.A OE1 no hydrogen 3.100 N/A ALA 226.A N TYR 223.A O no hydrogen 3.263 N/A GLN 228.A N LYS 225.A O no hydrogen 2.927 N/A HIS 229.A N LYS 225.A O no hydrogen 3.172 N/A HIS 229.A N ALA 226.A O no hydrogen 3.104 N/A HIS 229.A NE2 ASP 168.A OD1 no hydrogen 3.019 N/A GLN 231.A N HIS 229.A ND1 no hydrogen 2.778 N/A GLN 232.A NE2 ALA 226.A O no hydrogen 2.927 N/A GLN 232.A NE2 HIS 229.A O no hydrogen 3.061 N/A SER 233.A N ASP 41.A OD1 no hydrogen 2.882 N/A SER 233.A OG ASP 41.A OD2 no hydrogen 2.962 N/A SER 233.A OG GLU 45.A OE1 no hydrogen 3.274 N/A ARG 235.A NH1 GLN 232.A OE1 no hydrogen 2.882 N/A GLU 236.A N GLN 232.A O no hydrogen 3.120 N/A LYS 237.A N SER 233.A O no hydrogen 3.134 N/A LYS 237.A NZ ASN 54.A OD1 no hydrogen 2.915 N/A LYS 237.A NZ GLU 163.A OE2 no hydrogen 2.538 N/A TYR 238.A N ILE 234.A O no hydrogen 3.026 N/A TYR 238.A N ARG 235.A O no hydrogen 3.127 N/A TYR 238.A OH GLU 163.A OE1 no hydrogen 2.885 N/A LYS 239.A N GLU 236.A O no hydrogen 3.396 N/A ASN 240.A N LYS 237.A O no hydrogen 3.458 N/A TYR 243.A N ASN 240.A O no hydrogen 3.052 N/A HIS 244.A N SER 241.A O no hydrogen 2.927 N/A GLY 245.A N ASN 240.A O no hydrogen 2.983 N/A VAL 246.A N TYR 243.A O no hydrogen 3.398 N/A SER 247.A N TYR 238.A O no hydrogen 3.190 N/A SER 247.A OG ARG 235.A O no hydrogen 2.934 N/A LEU 248.A N GLY 245.A O no hydrogen 2.914 N/A LEU 249.A N VAL 246.A O no hydrogen 3.145 N/A