Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2x7o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG THR 5.A OG1 no hydrogen 3.183 N/A GLU 3.A N GLU 3.A OE1 no hydrogen 2.813 N/A THR 5.A OG1 SER 2.A O no hydrogen 2.792 N/A THR 6.A OG1 ASP 9.A OD2 no hydrogen 2.664 N/A LEU 7.A N GLU 57.A OE1 no hydrogen 2.807 N/A LYS 8.A N GLU 57.A OE2 no hydrogen 3.156 N/A ASP 9.A N THR 6.A O no hydrogen 3.223 N/A LEU 10.A N THR 6.A O no hydrogen 3.172 N/A ILE 11.A N LEU 7.A O no hydrogen 3.180 N/A ASP 13.A N ASP 9.A O no hydrogen 3.204 N/A THR 15.A N ILE 11.A O no hydrogen 3.138 N/A THR 15.A OG1 ILE 11.A O no hydrogen 2.707 N/A THR 16.A N TYR 12.A O no hydrogen 3.216 N/A THR 16.A OG1 TYR 12.A O no hydrogen 2.644 N/A GLN 28.A N PRO 24.A O no hydrogen 2.840 N/A GLN 28.A NE2 LEU 23.A O no hydrogen 2.769 N/A GLN 28.A NE2 GLN 80.A OE1 no hydrogen 3.130 N/A ARG 29.A N LEU 25.A O no hydrogen 3.261 N/A THR 30.A N LEU 26.A O no hydrogen 3.258 N/A THR 30.A OG1 LEU 26.A O no hydrogen 2.694 N/A ILE 31.A N VAL 27.A O no hydrogen 3.065 N/A ALA 32.A N GLN 28.A O no hydrogen 3.442 N/A ARG 33.A NE ASP 96.A OD1 no hydrogen 2.940 N/A ARG 33.A NH2 ASP 96.A OD1 no hydrogen 3.202 N/A ARG 33.A NH2 ASP 96.A OD2 no hydrogen 3.374 N/A THR 34.A N ILE 31.A O no hydrogen 3.057 N/A THR 34.A OG1 THR 30.A O no hydrogen 2.614 N/A ILE 35.A N ILE 31.A O no hydrogen 3.188 N/A VAL 36.A N LYS 53.A O no hydrogen 3.036 N/A GLN 38.A N ARG 51.A O no hydrogen 2.801 N/A GLN 38.A NE2 VAL 36.A O no hydrogen 3.641 N/A GLU 39.A N ARG 51.A O no hydrogen 3.473 N/A ILE 41.A N VAL 49.A O no hydrogen 3.097 N/A GLY 42.A N VAL 49.A O no hydrogen 3.232 N/A LYS 43.A NZ GLU 48.A OE2 no hydrogen 3.446 N/A ARG 45.A NH2 THR 205.A OG1 no hydrogen 3.157 N/A GLY 47.A N GLU 68.A OE2 no hydrogen 2.939 N/A GLU 48.A N ILE 63.A O no hydrogen 3.024 N/A VAL 49.A N GLY 42.A O no hydrogen 2.992 N/A TRP 50.A N VAL 61.A O no hydrogen 2.663 N/A TRP 50.A NE1 GLU 48.A OE1 no hydrogen 2.801 N/A ARG 51.A N GLU 39.A O no hydrogen 2.794 N/A ARG 51.A NE GLU 58.A OE2 no hydrogen 2.810 N/A ARG 51.A NH2 GLU 58.A OE2 no hydrogen 3.493 N/A GLY 52.A N VAL 59.A O no hydrogen 2.788 N/A LYS 53.A N VAL 36.A O no hydrogen 2.822 N/A TRP 54.A N GLU 57.A O no hydrogen 3.026 N/A ARG 55.A NH1 SER 2.A O no hydrogen 3.097 N/A ARG 55.A NH1 THR 5.A O no hydrogen 2.999 N/A ARG 55.A NH2 SER 2.A O no hydrogen 3.476 N/A VAL 59.A N GLY 52.A O no hydrogen 2.776 N/A ALA 60.A N SER 110.A O no hydrogen 3.002 N/A VAL 61.A N TRP 50.A O no hydrogen 2.907 N/A LYS 62.A N LEU 108.A O no hydrogen 2.764 N/A LYS 62.A NZ GLU 75.A OE1 no hydrogen 3.532 N/A ILE 63.A N GLU 48.A O no hydrogen 2.896 N/A PHE 64.A N LEU 106.A O no hydrogen 2.787 N/A SER 65.A N GLU 68.A OE2 no hydrogen 3.418 N/A SER 65.A OG GLU 68.A OE2 no hydrogen 3.213 N/A SER 66.A OG THR 102.A O no hydrogen 2.886 N/A TRP 72.A NE1 TRP 107.A O no hydrogen 2.952 N/A PHE 73.A N GLU 69.A O no hydrogen 3.129 N/A ARG 74.A N ARG 70.A O no hydrogen 3.184 N/A ARG 74.A NE ALA 185.A O no hydrogen 3.280 N/A ARG 74.A NH1 ASP 196.A OD1 no hydrogen 3.508 N/A ARG 74.A NH2 ALA 185.A O no hydrogen 2.977 N/A ARG 74.A NH2 ASP 196.A OD1 no hydrogen 2.757 N/A GLU 75.A N SER 71.A O no hydrogen 3.470 N/A ALA 76.A N TRP 72.A O no hydrogen 3.102 N/A GLU 77.A N PHE 73.A O no hydrogen 2.836 N/A ILE 78.A N ARG 74.A O no hydrogen 3.240 N/A TYR 79.A N GLU 75.A O no hydrogen 2.952 N/A GLN 80.A N ALA 76.A O no hydrogen 3.142 N/A GLN 80.A NE2 ALA 76.A O no hydrogen 3.521 N/A THR 81.A OG1 GLU 77.A O no hydrogen 3.276 N/A THR 81.A OG1 GLU 77.A OE1 no hydrogen 2.625 N/A VAL 82.A N GLN 80.A O no hydrogen 2.860 N/A ARG 85.A NH1 PHE 92.A O no hydrogen 2.836 N/A ASN 88.A N HIS 86.A ND1 no hydrogen 3.154 N/A ASN 88.A ND2 CYS 177.A O no hydrogen 3.454 N/A ILE 89.A N HIS 86.A O no hydrogen 3.251 N/A LEU 90.A N ILE 179.A O no hydrogen 3.130 N/A ILE 93.A N VAL 109.A O no hydrogen 2.906 N/A ALA 94.A N VAL 109.A O no hydrogen 3.322 N/A ALA 95.A N GLN 28.A OE1 no hydrogen 3.027 N/A ASP 96.A N TRP 107.A O no hydrogen 3.133 N/A LYS 98.A N GLN 105.A O no hydrogen 2.951 N/A THR 104.A OG1 GLY 101.A O no hydrogen 2.678 N/A TRP 107.A N ASP 96.A O no hydrogen 2.912 N/A LEU 108.A N LYS 62.A O no hydrogen 3.073 N/A VAL 109.A N ALA 94.A O no hydrogen 2.697 N/A SER 110.A N ALA 60.A O no hydrogen 2.942 N/A ASP 111.A N GLY 91.A O no hydrogen 2.990 N/A SER 117.A OG ASP 120.A OD2 no hydrogen 2.707 N/A LEU 118.A N ILE 169.A O no hydrogen 2.776 N/A PHE 119.A N SER 166.A O no hydrogen 3.295 N/A TYR 121.A N SER 117.A O no hydrogen 3.061 N/A LEU 122.A N LEU 118.A O no hydrogen 2.986 N/A ASN 123.A N PHE 119.A O no hydrogen 3.412 N/A TYR 125.A N TYR 121.A O no hydrogen 2.796 N/A MET 132.A N THR 128.A O no hydrogen 2.897 N/A LYS 134.A N GLU 130.A O no hydrogen 3.317 N/A LEU 135.A N GLY 131.A O no hydrogen 3.168 N/A ALA 136.A N MET 132.A O no hydrogen 3.226 N/A LEU 137.A N ILE 133.A O no hydrogen 2.784 N/A SER 138.A N LYS 134.A O no hydrogen 3.387 N/A SER 138.A OG LYS 134.A O no hydrogen 2.713 N/A SER 138.A OG LEU 135.A O no hydrogen 2.800 N/A THR 139.A N LEU 135.A O no hydrogen 3.311 N/A THR 139.A OG1 LEU 135.A O no hydrogen 2.694 N/A ALA 140.A N ALA 136.A O no hydrogen 3.037 N/A SER 141.A N LEU 137.A O no hydrogen 2.808 N/A SER 141.A OG LEU 137.A O no hydrogen 2.740 N/A GLY 142.A N SER 138.A O no hydrogen 2.955 N/A LEU 143.A N THR 139.A O no hydrogen 3.406 N/A ALA 144.A N ALA 140.A O no hydrogen 3.164 N/A HIS 145.A N SER 141.A O no hydrogen 3.247 N/A LEU 146.A N GLY 142.A O no hydrogen 3.358 N/A HIS 147.A N LEU 143.A O no hydrogen 3.011 N/A MET 148.A N ALA 144.A O no hydrogen 3.199 N/A ILE 150.A N LYS 156.A O no hydrogen 3.091 N/A GLN 154.A N GLY 152.A O no hydrogen 2.733 N/A LYS 156.A NZ HIS 145.A O no hydrogen 2.775 N/A LYS 156.A NZ LEU 146.A O no hydrogen 3.180 N/A LYS 156.A NZ MET 148.A O no hydrogen 2.815 N/A LYS 156.A NZ PRO 157.A O no hydrogen 3.247 N/A ALA 158.A N HIS 188.A O no hydrogen 2.887 N/A ILE 159.A N LEU 146.A O no hydrogen 2.763 N/A ALA 160.A N VAL 186.A O no hydrogen 3.076 N/A HIS 161.A NE2 ALA 180.A O no hydrogen 3.103 N/A ARG 162.A N ASP 230.A OD1 no hydrogen 2.770 N/A ARG 162.A N ASP 230.A OD2 no hydrogen 3.518 N/A ARG 162.A NE LEU 184.A O no hydrogen 2.798 N/A ARG 162.A NH2 LEU 184.A O no hydrogen 2.952 N/A LYS 165.A NZ THR 205.A OG1 no hydrogen 3.162 N/A ASN 168.A N LYS 165.A O no hydrogen 3.238 N/A ASN 168.A ND2 ASP 163.A O no hydrogen 2.867 N/A ASN 168.A ND2 ASP 163.A OD2 no hydrogen 2.907 N/A LEU 170.A N CYS 178.A O no hydrogen 3.110 N/A VAL 171.A N GLY 116.A O no hydrogen 3.018 N/A LYS 172.A N THR 176.A O no hydrogen 2.677 N/A LYS 172.A NZ GLU 87.A O no hydrogen 3.000 N/A GLY 175.A N LYS 172.A O no hydrogen 3.306 N/A CYS 177.A N SER 138.A OG no hydrogen 3.085 N/A CYS 177.A SG LEU 135.A O no hydrogen 3.944 N/A CYS 178.A N LEU 170.A O no hydrogen 2.862 N/A CYS 178.A SG HIS 113.A NE2 no hydrogen 3.810 N/A CYS 178.A SG LEU 170.A O no hydrogen 3.384 N/A ILE 179.A N ASN 88.A O no hydrogen 3.077 N/A ALA 180.A N ASN 168.A O no hydrogen 3.230 N/A ALA 185.A N LEU 182.A O no hydrogen 3.460 N/A VAL 186.A N ALA 160.A O no hydrogen 3.057 N/A ARG 187.A N ASP 196.A OD2 no hydrogen 3.073 N/A ARG 187.A NE ASP 196.A OD1 no hydrogen 2.862 N/A SER 190.A N GLU 149.A OE1 no hydrogen 3.226 N/A SER 190.A N GLU 149.A OE2 no hydrogen 2.995 N/A SER 190.A OG GLU 149.A OE2 no hydrogen 2.710 N/A THR 192.A OG1 ASP 189.A OD2 no hydrogen 2.842 N/A ASP 193.A N ASP 189.A O no hydrogen 2.963 N/A HIS 201.A ND1 ASN 200.A OD1 no hydrogen 2.962 N/A ARG 202.A NH1 VAL 213.A O no hydrogen 2.758 N/A ARG 202.A NH2 LEU 214.A O no hydrogen 3.543 N/A THR 205.A N ASP 163.A OD1 no hydrogen 2.821 N/A THR 205.A OG1 ASP 163.A OD1 no hydrogen 3.071 N/A ARG 207.A NE PRO 257.A O no hydrogen 2.804 N/A ARG 207.A NH1 PRO 263.A O no hydrogen 3.314 N/A TYR 208.A N THR 205.A O no hydrogen 3.341 N/A TYR 208.A OH GLU 240.A OE2 no hydrogen 3.021 N/A MET 209.A N LYS 206.A O no hydrogen 3.446 N/A GLU 212.A N GLU 212.A OE2 no hydrogen 3.093 N/A VAL 213.A N ALA 210.A O no hydrogen 3.126 N/A LEU 214.A N ALA 210.A O no hydrogen 3.110 N/A ASP 215.A N PRO 211.A O no hydrogen 3.064 N/A SER 217.A OG GLU 212.A O no hydrogen 3.503 N/A SER 217.A OG ASP 215.A OD1 no hydrogen 3.012 N/A ILE 218.A N GLU 212.A O no hydrogen 3.071 N/A HIS 222.A N ASN 219.A OD1 no hydrogen 3.155 N/A SER 225.A OG ASN 219.A O no hydrogen 2.761 N/A SER 225.A OG HIS 222.A O no hydrogen 2.726 N/A PHE 226.A N PHE 223.A O no hydrogen 3.100 N/A LYS 227.A N PHE 223.A O no hydrogen 3.290 N/A LYS 227.A NZ HIS 147.A O no hydrogen 3.130 N/A LYS 227.A NZ GLU 224.A OE2 no hydrogen 3.472 N/A ARG 228.A N GLU 224.A O no hydrogen 2.911 N/A ALA 229.A N SER 225.A O no hydrogen 3.173 N/A TYR 232.A OH TYR 258.A OH no hydrogen 2.816 N/A ALA 233.A N ALA 229.A O no hydrogen 3.345 N/A MET 234.A N ASP 230.A O no hydrogen 2.855 N/A GLY 235.A N ILE 231.A O no hydrogen 3.032 N/A LEU 236.A N TYR 232.A O no hydrogen 3.327 N/A VAL 237.A N ALA 233.A O no hydrogen 3.401 N/A PHE 238.A N MET 234.A O no hydrogen 2.943 N/A TRP 239.A N GLY 235.A O no hydrogen 3.131 N/A TRP 239.A NE1 ASN 283.A O no hydrogen 2.895 N/A ILE 241.A N VAL 237.A O no hydrogen 3.341 N/A ALA 242.A N PHE 238.A O no hydrogen 3.507 N/A CYS 245.A N ALA 242.A O no hydrogen 3.410 N/A SER 246.A N VAL 127.A O no hydrogen 3.071 N/A SER 246.A OG HIS 251.A ND1 no hydrogen 3.229 N/A HIS 251.A ND1 SER 246.A OG no hydrogen 3.229 N/A GLU 252.A N ARG 243.A O no hydrogen 3.324 N/A TYR 254.A OH GLU 240.A OE1 no hydrogen 2.703 N/A GLN 255.A NE2 TYR 254.A O no hydrogen 3.061 N/A TYR 258.A OH TYR 232.A OH no hydrogen 2.816 N/A VAL 262.A N TYR 258.A O no hydrogen 2.774 N/A SER 267.A OG GLU 270.A OE1 no hydrogen 2.964 N/A MET 271.A N SER 267.A O no hydrogen 3.323 N/A ARG 272.A N VAL 268.A O no hydrogen 3.196 N/A VAL 275.A N MET 271.A O no hydrogen 3.210 N/A CYS 276.A N ARG 272.A O no hydrogen 3.046 N/A CYS 276.A SG PRO 211.A O no hydrogen 3.335 N/A CYS 276.A SG ASP 215.A OD2 no hydrogen 3.352 N/A GLU 277.A N ARG 272.A O no hydrogen 3.029 N/A GLN 278.A N LYS 273.A O no hydrogen 3.140 N/A GLN 278.A NE2 LYS 273.A O no hydrogen 3.105 N/A LEU 280.A N VAL 274.A O no hydrogen 2.846 N/A ARG 281.A NE TRP 305.A O no hydrogen 2.933 N/A ARG 287.A NE GLU 252.A OE1 no hydrogen 2.750 N/A ARG 287.A NE GLU 252.A OE2 no hydrogen 3.438 N/A ARG 287.A NH2 ALA 242.A O no hydrogen 3.485 N/A ARG 287.A NH2 GLU 252.A OE1 no hydrogen 2.884 N/A TRP 288.A N PRO 285.A O no hydrogen 3.478 N/A TRP 288.A NE1 GLU 252.A OE2 no hydrogen 3.080 N/A GLN 289.A N ASN 286.A O no hydrogen 3.419 N/A SER 290.A N ARG 287.A O no hydrogen 3.395 N/A SER 290.A OG ARG 287.A O no hydrogen 2.748 N/A ARG 295.A N CYS 291.A O no hydrogen 3.297 N/A VAL 296.A N GLU 292.A O no hydrogen 3.015 N/A MET 297.A N ALA 293.A O no hydrogen 3.368 N/A ALA 298.A N LEU 294.A O no hydrogen 3.348 N/A LYS 299.A N ARG 295.A O no hydrogen 3.224 N/A ILE 300.A N VAL 296.A O no hydrogen 3.160 N/A MET 301.A N MET 297.A O no hydrogen 3.082 N/A ARG 302.A N ALA 298.A O no hydrogen 3.340 N/A CYS 304.A N MET 301.A O no hydrogen 3.264 N/A CYS 304.A SG ILE 300.A O no hydrogen 3.214 N/A TRP 305.A N MET 301.A O no hydrogen 3.118 N/A ALA 311.A N ASN 308.A OD1 no hydrogen 3.394 N/A ARG 312.A N GLY 309.A O no hydrogen 3.267 N/A ARG 312.A NE TYR 306.A O no hydrogen 3.184 N/A ARG 312.A NH1 ARG 228.A O no hydrogen 3.028 N/A ARG 312.A NH2 TYR 306.A O no hydrogen 2.873 N/A ARG 317.A N THR 314.A O no hydrogen 3.089 N/A ILE 318.A N THR 314.A O no hydrogen 3.246 N/A LYS 319.A N ALA 315.A O no hydrogen 3.419 N/A LYS 320.A N LEU 316.A O no hydrogen 3.016 N/A THR 321.A N ARG 317.A O no hydrogen 3.128 N/A THR 321.A OG1 ARG 317.A O no hydrogen 2.947 N/A THR 321.A OG1 ILE 318.A O no hydrogen 3.062 N/A LEU 322.A N ILE 318.A O no hydrogen 3.213 N/A SER 323.A N LYS 319.A O no hydrogen 3.217 N/A GLN 324.A N LYS 320.A O no hydrogen 3.364 N/A LEU 325.A N THR 321.A O no hydrogen 3.268 N/A SER 326.A N LEU 322.A O no hydrogen 3.005 N/A SER 326.A OG LEU 322.A O no hydrogen 3.408 N/A SER 326.A OG SER 323.A O no hydrogen 2.708 N/A GLN 327.A NE2 SER 323.A O no hydrogen 2.798 N/A