Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2x7x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A N ASP 59.A OD2 no hydrogen 2.666 N/A ILE 4.A N SER 33.A O no hydrogen 2.770 N/A GLY 5.A N LEU 60.A O no hydrogen 2.965 N/A VAL 6.A N GLU 35.A O no hydrogen 2.910 N/A ALA 7.A N ILE 62.A O no hydrogen 2.671 N/A GLN 8.A N ARG 37.A O no hydrogen 3.004 N/A GLN 8.A NE2 ASN 19.A OD1 no hydrogen 2.907 N/A CYS 9.A SG SER 10.A OG no hydrogen 3.720 N/A CYS 9.A SG SER 64.A OG no hydrogen 3.245 N/A SER 13.A OG ASN 224.A OD1 no hydrogen 2.987 N/A TRP 14.A NE1 TYR 240.A O no hydrogen 2.889 N/A ARG 15.A N ASP 12.A OD2 no hydrogen 2.917 N/A ARG 15.A NH1 ASP 89.A OD2 no hydrogen 2.926 N/A ARG 15.A NH2 GLN 8.A OE1 no hydrogen 3.122 N/A ARG 15.A NH2 ASP 89.A OD2 no hydrogen 2.988 N/A HIS 16.A N ASP 12.A O no hydrogen 2.757 N/A LYS 17.A N SER 13.A O no hydrogen 3.141 N/A LYS 17.A NZ GLU 21.A OE1 no hydrogen 3.516 N/A LYS 17.A NZ THR 242.A OG1 no hydrogen 3.135 N/A MET 18.A N TRP 14.A O no hydrogen 3.162 N/A ASN 19.A N ARG 15.A O no hydrogen 2.789 N/A ASP 20.A N HIS 16.A O no hydrogen 3.088 N/A GLU 21.A N LYS 17.A O no hydrogen 3.185 N/A ILE 22.A N MET 18.A O no hydrogen 3.002 N/A ILE 22.A N ASN 19.A O no hydrogen 2.744 N/A LEU 23.A N ASN 19.A O no hydrogen 2.995 N/A ARG 24.A N ASP 20.A O no hydrogen 2.996 N/A GLU 25.A N GLU 21.A O no hydrogen 3.269 N/A ALA 26.A N ILE 22.A O no hydrogen 2.892 N/A ALA 26.A N LEU 23.A O no hydrogen 3.077 N/A PHE 28.A N GLU 25.A O no hydrogen 3.192 N/A TYR 29.A N ALA 26.A O no hydrogen 2.847 N/A SER 33.A N PHE 2.A O no hydrogen 2.712 N/A GLU 35.A N ILE 4.A O no hydrogen 2.963 N/A ARG 37.A N VAL 6.A O no hydrogen 3.073 N/A ARG 37.A NE ASP 49.A OD1 no hydrogen 2.632 N/A ARG 37.A NH2 ASP 49.A OD1 no hydrogen 3.200 N/A ALA 39.A N GLN 8.A O no hydrogen 2.761 N/A GLY 40.A N SER 38.A OG no hydrogen 3.114 N/A ASP 41.A N CYS 9.A O no hydrogen 2.767 N/A ASP 42.A N ALA 39.A O no hydrogen 3.219 N/A ASN 43.A ND2 GLU 67.A OE1 no hydrogen 3.050 N/A LYS 45.A N ASP 42.A OD2 no hydrogen 3.069 N/A GLN 46.A N ASP 42.A O no hydrogen 3.105 N/A GLN 46.A NE2 SER 64.A O no hydrogen 2.751 N/A ALA 47.A N ASN 43.A O no hydrogen 3.041 N/A GLU 48.A N SER 44.A O no hydrogen 2.854 N/A ASP 49.A N LYS 45.A O no hydrogen 2.735 N/A VAL 50.A N GLN 46.A O no hydrogen 2.925 N/A HIS 51.A N ALA 47.A O no hydrogen 2.704 N/A TYR 52.A N GLU 48.A O no hydrogen 2.872 N/A TYR 52.A OH GLU 35.A OE2 no hydrogen 3.103 N/A PHE 53.A N ASP 49.A O no hydrogen 3.044 N/A MET 54.A N VAL 50.A O no hydrogen 2.934 N/A ASP 55.A N HIS 51.A O no hydrogen 2.869 N/A GLU 56.A N TYR 52.A O no hydrogen 3.036 N/A GLY 57.A N MET 54.A O no hydrogen 3.086 N/A VAL 58.A N PHE 53.A O no hydrogen 3.169 N/A ASP 59.A N ARG 3.A O no hydrogen 2.830 N/A LEU 61.A N PRO 84.A O no hydrogen 2.943 N/A ILE 62.A N GLY 5.A O no hydrogen 2.723 N/A ILE 63.A N ILE 86.A O no hydrogen 2.866 N/A SER 64.A N ALA 7.A O no hydrogen 3.016 N/A SER 64.A OG ASP 89.A OD2 no hydrogen 3.231 N/A ASN 66.A N GLN 46.A OE1 no hydrogen 2.866 N/A ASN 66.A ND2 ASP 41.A O no hydrogen 3.585 N/A ASN 66.A ND2 ASN 43.A OD1 no hydrogen 2.828 N/A ALA 68.A N GLY 134.A O no hydrogen 2.863 N/A THR 72.A N ALA 69.A O no hydrogen 3.195 N/A THR 72.A OG1 ALA 68.A O no hydrogen 2.710 N/A VAL 75.A N MET 71.A O no hydrogen 2.968 N/A GLU 76.A N THR 72.A O no hydrogen 2.998 N/A GLU 77.A N PRO 73.A O no hydrogen 3.031 N/A TYR 79.A N VAL 75.A O no hydrogen 2.980 N/A GLN 80.A N GLU 76.A O no hydrogen 2.764 N/A LYS 81.A N GLU 77.A O no hydrogen 2.846 N/A GLY 82.A N TYR 79.A O no hydrogen 3.021 N/A VAL 85.A N THR 98.A OG1 no hydrogen 2.794 N/A ILE 86.A N LEU 61.A O no hydrogen 2.670 N/A LEU 87.A N ALA 99.A O no hydrogen 2.896 N/A VAL 88.A N ILE 63.A O no hydrogen 2.981 N/A ASP 89.A N ILE 101.A O no hydrogen 3.035 N/A ARG 90.A N VAL 88.A O no hydrogen 2.567 N/A ARG 90.A NH1 ASN 66.A O no hydrogen 3.111 N/A LYS 91.A N THR 136.A OG1 no hydrogen 2.921 N/A LYS 91.A NZ GLU 140.A OE1 no hydrogen 3.527 N/A LYS 91.A NZ GLU 140.A OE2 no hydrogen 3.005 N/A LEU 93.A N THR 72.A OG1 no hydrogen 3.043 N/A SER 94.A OG GLU 76.A OE1 no hydrogen 2.916 N/A THR 98.A N VAL 85.A O no hydrogen 2.856 N/A THR 98.A OG1 VAL 85.A O no hydrogen 3.444 N/A ALA 99.A N VAL 85.A O no hydrogen 3.247 N/A TYR 100.A N LYS 262.A O no hydrogen 2.785 N/A ILE 101.A N LEU 87.A O no hydrogen 2.881 N/A GLY 102.A N THR 264.A O no hydrogen 3.072 N/A ASN 105.A ND2 TYR 240.A OH no hydrogen 3.129 N/A TYR 106.A N ASP 104.A OD2 no hydrogen 2.951 N/A GLU 107.A N ASP 104.A OD2 no hydrogen 3.488 N/A ILE 108.A N ASP 104.A O no hydrogen 3.152 N/A GLY 109.A N ASN 105.A O no hydrogen 3.073 N/A ARG 110.A N TYR 106.A O no hydrogen 2.912 N/A SER 111.A N GLU 107.A O no hydrogen 2.828 N/A SER 111.A OG GLU 107.A O no hydrogen 3.053 N/A VAL 112.A N ILE 108.A O no hydrogen 2.817 N/A GLY 113.A N GLY 109.A O no hydrogen 2.829 N/A ASN 114.A N ARG 110.A O no hydrogen 2.903 N/A TYR 115.A N SER 111.A O no hydrogen 2.927 N/A ILE 116.A N VAL 112.A O no hydrogen 3.060 N/A ALA 117.A N GLY 113.A O no hydrogen 2.987 N/A SER 118.A N ASN 114.A O no hydrogen 3.017 N/A SER 119.A N TYR 115.A O no hydrogen 3.023 N/A LEU 120.A N ILE 116.A O no hydrogen 2.843 N/A LYS 121.A N SER 118.A O no hydrogen 3.170 N/A GLY 122.A N ALA 117.A O no hydrogen 2.865 N/A LYS 123.A N LEU 120.A O no hydrogen 3.195 N/A GLY 124.A N ASP 154.A O no hydrogen 2.825 N/A ASN 125.A N ASP 185.A OD2 no hydrogen 2.744 N/A ASN 125.A ND2 LYS 183.A O no hydrogen 3.069 N/A ILE 126.A N LYS 156.A O no hydrogen 2.855 N/A VAL 127.A N ALA 186.A O no hydrogen 2.937 N/A GLU 128.A N ASP 159.A O no hydrogen 2.882 N/A LEU 129.A N TYR 188.A O no hydrogen 2.915 N/A THR 130.A N ALA 161.A O no hydrogen 2.799 N/A THR 130.A OG1 GLY 131.A O no hydrogen 2.753 N/A GLY 131.A N HIS 190.A ND1 no hydrogen 3.148 N/A SER 133.A N ASP 162.A OD2 no hydrogen 2.877 N/A SER 133.A OG ASP 162.A OD2 no hydrogen 2.804 N/A SER 135.A N LEU 132.A O no hydrogen 2.972 N/A SER 135.A OG LEU 132.A O no hydrogen 2.625 N/A MET 139.A N SER 135.A O no hydrogen 3.248 N/A GLU 140.A N THR 136.A O no hydrogen 3.059 N/A ARG 141.A N PRO 137.A O no hydrogen 2.730 N/A ARG 141.A NE ASN 105.A OD1 no hydrogen 2.801 N/A ARG 141.A NH2 ASN 105.A OD1 no hydrogen 2.861 N/A HIS 142.A N ALA 138.A O no hydrogen 3.150 N/A HIS 142.A N MET 139.A O no hydrogen 3.143 N/A HIS 142.A ND1 GLU 128.A OE1 no hydrogen 2.495 N/A HIS 142.A ND1 GLU 128.A OE2 no hydrogen 3.276 N/A GLN 143.A N MET 139.A O no hydrogen 2.966 N/A GLY 144.A N GLU 140.A O no hydrogen 2.925 N/A MET 146.A N HIS 142.A O no hydrogen 2.919 N/A ALA 147.A N GLN 143.A O no hydrogen 2.866 N/A ALA 148.A N GLY 144.A O no hydrogen 3.127 N/A ILE 149.A N PHE 145.A O no hydrogen 3.160 N/A SER 150.A N MET 146.A O no hydrogen 3.152 N/A SER 150.A OG MET 146.A O no hydrogen 3.543 N/A SER 150.A OG ALA 147.A O no hydrogen 2.480 N/A LYS 151.A N ALA 148.A O no hydrogen 3.323 N/A PHE 152.A N ILE 149.A O no hydrogen 3.209 N/A ILE 155.A N PHE 152.A O no hydrogen 3.204 N/A LYS 156.A N GLY 124.A O no hydrogen 2.933 N/A ILE 158.A N ILE 126.A O no hydrogen 3.000 N/A LYS 160.A N ASP 159.A OD1 no hydrogen 2.747 N/A ALA 161.A N GLU 128.A O no hydrogen 3.043 N/A ALA 163.A N THR 130.A O no hydrogen 2.761 N/A ALA 164.A N ASP 162.A OD1 no hydrogen 2.909 N/A GLU 166.A N ALA 163.A O no hydrogen 2.947 N/A ARG 167.A NH1 GLU 171.A OE2 no hydrogen 3.197 N/A ARG 167.A NH1 GLN 200.A OE1 no hydrogen 3.085 N/A ALA 170.A N GLU 166.A O no hydrogen 3.437 N/A GLU 171.A N ARG 167.A O no hydrogen 3.045 N/A ILE 172.A N GLY 168.A O no hydrogen 3.504 N/A GLU 173.A N PRO 169.A O no hydrogen 2.914 N/A MET 174.A N ALA 170.A O no hydrogen 2.839 N/A ASP 175.A N GLU 171.A O no hydrogen 2.990 N/A SER 176.A N ILE 172.A O no hydrogen 3.084 N/A MET 177.A N GLU 173.A O no hydrogen 3.010 N/A LEU 178.A N MET 174.A O no hydrogen 2.894 N/A ARG 179.A N ASP 175.A O no hydrogen 3.114 N/A ARG 180.A N SER 176.A O no hydrogen 3.190 N/A ARG 180.A N MET 177.A O no hydrogen 3.212 N/A ARG 180.A NE SER 176.A OG no hydrogen 3.005 N/A ARG 180.A NH1 ASP 159.A OD2 no hydrogen 3.110 N/A ARG 180.A NH2 ASP 159.A OD2 no hydrogen 3.176 N/A ARG 180.A NH2 SER 176.A OG no hydrogen 2.914 N/A HIS 181.A N LEU 178.A O no hydrogen 3.370 N/A HIS 181.A NE2 ASP 159.A OD2 no hydrogen 2.888 N/A LYS 183.A NZ ASP 185.A OD2 no hydrogen 3.123 N/A ASP 185.A N ASN 125.A O no hydrogen 2.840 N/A ALA 186.A N ASN 125.A O no hydrogen 3.185 N/A VAL 187.A N ILE 212.A O no hydrogen 2.889 N/A TYR 188.A N VAL 127.A O no hydrogen 2.900 N/A TYR 188.A OH ARG 141.A O no hydrogen 2.824 N/A ALA 189.A N VAL 214.A O no hydrogen 2.786 N/A HIS 190.A N LEU 129.A O no hydrogen 3.034 N/A HIS 190.A NE2 GLU 128.A OE2 no hydrogen 2.806 N/A ASN 191.A ND2 TRP 165.A O no hydrogen 3.002 N/A ARG 193.A N ASN 191.A OD1 no hydrogen 3.064 N/A ARG 193.A NE GLU 166.A OE2 no hydrogen 2.980 N/A ARG 193.A NH2 GLU 166.A OE1 no hydrogen 3.037 N/A ILE 194.A N ASN 191.A OD1 no hydrogen 2.705 N/A ALA 195.A N ASN 191.A O no hydrogen 3.094 N/A GLY 197.A N ILE 194.A O no hydrogen 3.037 N/A ALA 198.A N ILE 194.A O no hydrogen 3.188 N/A TYR 199.A N ALA 195.A O no hydrogen 3.052 N/A GLN 200.A N PRO 196.A O no hydrogen 2.920 N/A ALA 201.A N GLY 197.A O no hydrogen 3.069 N/A ALA 202.A N ALA 198.A O no hydrogen 3.039 N/A LYS 203.A N TYR 199.A O no hydrogen 2.730 N/A MET 204.A N GLN 200.A O no hydrogen 3.082 N/A ALA 205.A N ALA 201.A O no hydrogen 3.250 N/A ALA 205.A N ALA 202.A O no hydrogen 3.001 N/A GLY 206.A N LYS 203.A O no hydrogen 2.942 N/A ARG 207.A N ALA 202.A O no hydrogen 2.790 N/A ARG 207.A NE GLU 210.A OE1 no hydrogen 2.938 N/A ARG 207.A NH1 LEU 178.A O no hydrogen 2.908 N/A ARG 207.A NH1 HIS 181.A O no hydrogen 3.420 N/A ARG 207.A NH2 HIS 181.A O no hydrogen 2.792 N/A GLU 208.A N GLU 208.A OE1 no hydrogen 2.733 N/A GLU 210.A N ARG 207.A O no hydrogen 3.128 N/A ILE 212.A N ASP 185.A O no hydrogen 3.091 N/A PHE 213.A N ASP 235.A OD2 no hydrogen 2.786 N/A VAL 214.A N VAL 187.A O no hydrogen 2.957 N/A GLY 215.A N ALA 236.A O no hydrogen 3.034 N/A ASP 217.A N PHE 238.A O no hydrogen 2.625 N/A ALA 218.A N ASP 192.A OD2 no hydrogen 2.664 N/A GLY 223.A N GLU 227.A OE1 no hydrogen 3.040 N/A ASN 224.A ND2 PRO 220.A O no hydrogen 2.842 N/A LEU 226.A N LEU 219.A O no hydrogen 3.129 N/A LEU 228.A N ASN 224.A O no hydrogen 3.089 N/A VAL 229.A N GLY 225.A O no hydrogen 3.006 N/A VAL 229.A N LEU 226.A O no hydrogen 3.049 N/A LEU 230.A N LEU 226.A O no hydrogen 2.965 N/A ASP 231.A N GLU 227.A O no hydrogen 2.824 N/A SER 232.A N VAL 229.A O no hydrogen 2.966 N/A VAL 233.A N LEU 228.A O no hydrogen 2.826 N/A LEU 234.A N LEU 228.A O no hydrogen 2.898 N/A ASP 235.A N PHE 213.A O no hydrogen 2.825 N/A ALA 236.A N PHE 213.A O no hydrogen 3.337 N/A THR 237.A N VAL 271.A O no hydrogen 2.923 N/A THR 237.A OG1 ASP 192.A OD1 no hydrogen 2.633 N/A THR 237.A OG1 ASP 192.A OD2 no hydrogen 3.248 N/A PHE 238.A N GLY 215.A O no hydrogen 3.217 N/A ILE 239.A N ALA 269.A O no hydrogen 2.866 N/A TYR 240.A N ASP 217.A O no hydrogen 2.992 N/A TYR 240.A OH ASP 89.A OD1 no hydrogen 2.410 N/A THR 242.A OG1 GLU 21.A OE1 no hydrogen 3.354 N/A THR 242.A OG1 GLU 21.A OE2 no hydrogen 2.691 N/A GLY 244.A N GLU 21.A OE2 no hydrogen 2.801 N/A LYS 246.A N ASN 243.A O no hydrogen 3.057 N/A VAL 247.A N ASN 243.A O no hydrogen 3.314 N/A VAL 247.A N GLY 244.A O no hydrogen 3.198 N/A LEU 248.A N GLY 244.A O no hydrogen 3.191 N/A GLN 249.A N ASP 245.A O no hydrogen 3.035 N/A LEU 250.A N LYS 246.A O no hydrogen 3.306 N/A ALA 251.A N VAL 247.A O no hydrogen 3.117 N/A MET 252.A N LEU 248.A O no hydrogen 2.814 N/A ASP 253.A N GLN 249.A O no hydrogen 2.970 N/A ILE 254.A N LEU 250.A O no hydrogen 3.104 N/A LEU 255.A N ALA 251.A O no hydrogen 2.936 N/A GLU 256.A N MET 252.A O no hydrogen 2.810 N/A LYS 257.A N ILE 254.A O no hydrogen 3.163 N/A LYS 258.A NZ GLU 256.A OE1 no hydrogen 3.313 N/A LYS 262.A NZ TYR 260.A O no hydrogen 3.220 N/A THR 264.A N TYR 100.A O no hydrogen 2.922 N/A MET 266.A N GLY 102.A O no hydrogen 2.733 N/A THR 268.A OG1 ILE 239.A O no hydrogen 2.730 N/A VAL 271.A N THR 237.A O no hydrogen 2.734 N/A ASP 272.A N ASN 275.A OD1 no hydrogen 2.918 N/A THR 274.A OG1 ASP 272.A OD1 no hydrogen 3.212 N/A ASN 275.A N ASP 272.A O no hydrogen 3.031 N/A ASN 275.A ND2 VAL 270.A O no hydrogen 2.992 N/A MET 279.A N ASN 275.A O no hydrogen 3.363 N/A GLN 280.A N ALA 276.A O no hydrogen 2.917 N/A LEU 281.A N HIS 277.A O no hydrogen 3.080 N/A GLN 282.A N VAL 278.A O no hydrogen 3.159 N/A THR 283.A N MET 279.A O no hydrogen 2.918 N/A THR 283.A OG1 MET 279.A O no hydrogen 3.181 N/A THR 283.A OG1 GLN 280.A O no hydrogen 3.203 N/A THR 284.A N GLN 280.A O no hydrogen 2.859 N/A THR 284.A OG1 GLN 280.A O no hydrogen 3.071 N/A HIS 285.A N LEU 281.A O no hydrogen 3.343 N/A ILE 286.A N GLN 282.A O no hydrogen 3.025 N/A SER 287.A N THR 283.A O no hydrogen 2.984 N/A SER 287.A OG THR 283.A O no hydrogen 3.524 N/A LEU 289.A N HIS 285.A O no hydrogen 2.983 N/A ASP 290.A N ILE 286.A O no hydrogen 2.910 N/A LYS 291.A N SER 287.A O no hydrogen 3.186 N/A LYS 292.A N GLU 288.A O no hydrogen 3.124 N/A ILE 293.A N LEU 289.A O no hydrogen 3.180 N/A GLU 294.A N ASP 290.A O no hydrogen 2.951 N/A THR 295.A N LYS 291.A O no hydrogen 2.966 N/A THR 295.A OG1 LYS 291.A O no hydrogen 2.731 N/A LEU 296.A N LYS 292.A O no hydrogen 2.898 N/A ASN 297.A N ILE 293.A O no hydrogen 2.986 N/A GLY 298.A N GLU 294.A O no hydrogen 3.100 N/A ARG 299.A N THR 295.A O no hydrogen 3.325 N/A ILE 300.A N ASN 297.A O no hydrogen 3.300 N/A