Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2xzg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N MET 2.A O.A no hydrogen 3.499 N/A ILE 5.A N MET 2.A O.B no hydrogen 3.027 N/A ARG 9.A N CYS 329.A O no hydrogen 2.849 N/A GLN 11.A N SER 327.A O no hydrogen 2.938 N/A HIS 13.A N VAL 325.A O no hydrogen 2.757 N/A HIS 13.A NE2 SER 327.A OG no hydrogen 2.663 N/A GLN 15.A NE2 GLU 12.A OE1 no hydrogen 3.193 N/A GLN 15.A NE2 GLU 12.A OE2 no hydrogen 3.491 N/A LEU 16.A N GLY 323.A O no hydrogen 2.838 N/A ASN 18.A N GLN 15.A O no hydrogen 3.044 N/A LEU 19.A N LEU 16.A O no hydrogen 2.973 N/A GLY 20.A N GLN 17.A O no hydrogen 3.437 N/A ILE 21.A N LEU 16.A O no hydrogen 3.336 N/A ASN 22.A N GLU 43.A OE2 no hydrogen 3.022 N/A ALA 24.A N ASN 22.A OD1 no hydrogen 2.814 N/A ASN 25.A N ASN 22.A O no hydrogen 2.872 N/A ASN 25.A ND2 GLU 43.A OE2 no hydrogen 3.011 N/A ILE 26.A N PRO 23.A O no hydrogen 3.082 N/A THR 30.A N GLY 27.A O no hydrogen 3.099 N/A THR 30.A OG1 ASN 25.A O no hydrogen 2.633 N/A THR 30.A OG1 GLY 27.A O no hydrogen 3.491 N/A LEU 31.A N GLY 27.A O no hydrogen 2.910 N/A THR 32.A N CYS 40.A O no hydrogen 2.839 N/A THR 32.A OG1 ALA 72.A O no hydrogen 2.810 N/A SER 35.A OG PRO 76.A O no hydrogen 2.691 N/A LYS 37.A N SER 35.A OG no hydrogen 3.246 N/A LYS 37.A NZ ALA 77.A O no hydrogen 2.968 N/A ILE 39.A N ILE 54.A O no hydrogen 2.968 N/A CYS 40.A N THR 32.A O no hydrogen 2.964 N/A CYS 40.A SG VAL 52.A O no hydrogen 3.984 N/A CYS 40.A SG ALA 72.A O no hydrogen 3.878 N/A ILE 41.A N VAL 52.A O no hydrogen 2.810 N/A ARG 42.A N THR 30.A O no hydrogen 2.841 N/A ARG 42.A NH1 ALA 69.A O no hydrogen 3.304 N/A ARG 42.A NH2 SER 29.A O no hydrogen 2.834 N/A GLU 43.A N GLN 50.A O no hydrogen 2.997 N/A LYS 44.A NZ GLU 43.A O no hydrogen 3.232 N/A VAL 45.A N GLN 48.A O no hydrogen 2.979 N/A GLN 48.A N VAL 45.A O no hydrogen 3.227 N/A GLN 50.A N GLU 43.A O no hydrogen 2.731 N/A GLN 50.A NE2 GLN 48.A OE1 no hydrogen 3.052 N/A VAL 51.A N ARG 65.A O no hydrogen 2.831 N/A VAL 52.A N ILE 41.A O no hydrogen 2.734 N/A ILE 53.A N ILE 63.A O no hydrogen 2.916 N/A ILE 54.A N ILE 39.A O no hydrogen 2.700 N/A MET 56.A N LYS 37.A O no hydrogen 2.986 N/A ASN 57.A N ASP 55.A OD1 no hydrogen 2.877 N/A ASP 58.A N ASP 55.A O no hydrogen 2.889 N/A SER 60.A OG ASN 61.A OD1 no hydrogen 3.306 N/A ASN 61.A ND2 ASP 58.A OD2 no hydrogen 3.400 N/A ILE 63.A N ILE 53.A O no hydrogen 3.253 N/A ARG 64.A NH1 GLU 43.A OE1 no hydrogen 2.677 N/A ARG 64.A NH1 GLN 50.A OE1 no hydrogen 2.788 N/A ARG 64.A NH2 GLU 43.A OE1 no hydrogen 2.751 N/A ARG 65.A N VAL 51.A O no hydrogen 2.944 N/A ARG 65.A NH1 PRO 66.A O no hydrogen 3.152 N/A ILE 67.A N ALA 49.A O no hydrogen 3.094 N/A ASP 70.A N LYS 84.A O no hydrogen 2.717 N/A ILE 73.A N ALA 82.A O no hydrogen 2.946 N/A ASN 75.A N VAL 80.A O no hydrogen 2.912 N/A ASN 75.A ND2 LEU 117.A O no hydrogen 2.890 N/A ALA 77.A N ASN 75.A OD1 no hydrogen 2.768 N/A SER 78.A N ASN 75.A OD1 no hydrogen 2.912 N/A VAL 80.A N SER 78.A O no hydrogen 2.800 N/A ILE 81.A N PHE 92.A O no hydrogen 2.976 N/A ALA 82.A N ILE 73.A O no hydrogen 2.923 N/A LEU 83.A N GLN 90.A O no hydrogen 2.807 N/A LYS 84.A N SER 71.A O no hydrogen 3.035 N/A LYS 84.A NZ ASP 70.A OD1 no hydrogen 2.587 N/A LYS 84.A NZ VAL 109.A O no hydrogen 3.079 N/A ALA 85.A N THR 88.A O no hydrogen 2.998 N/A GLY 86.A N ASP 70.A OD2 no hydrogen 3.046 N/A LYS 87.A NZ ASP 108.A OD1 no hydrogen 2.900 N/A THR 88.A N ALA 85.A O no hydrogen 3.166 N/A LEU 89.A N HIS 103.A O no hydrogen 2.739 N/A GLN 90.A N LEU 83.A O no hydrogen 2.914 N/A ILE 91.A N LYS 101.A O no hydrogen 2.937 N/A PHE 92.A N ILE 81.A O no hydrogen 2.842 N/A ASN 93.A N SER 98.A O no hydrogen 2.800 N/A ILE 94.A N LYS 79.A O no hydrogen 2.981 N/A MET 96.A N ASN 93.A OD1 no hydrogen 3.043 N/A LYS 97.A N ILE 94.A O no hydrogen 3.165 N/A SER 98.A N ASN 93.A O no hydrogen 3.139 N/A SER 98.A OG MET 96.A O no hydrogen 2.785 N/A MET 100.A N ILE 91.A O no hydrogen 2.798 N/A LYS 101.A N ILE 91.A O no hydrogen 3.340 N/A LYS 101.A NZ SER 132.A O no hydrogen 2.688 N/A LYS 101.A NZ GLU 134.A O no hydrogen 2.911 N/A LYS 101.A NZ SER 137.A O no hydrogen 2.780 N/A HIS 103.A N LEU 89.A O no hydrogen 2.939 N/A MET 105.A N LYS 87.A O no hydrogen 2.860 N/A THR 110.A N.A VAL 123.A O no hydrogen 2.890 N/A THR 110.A N.B VAL 123.A O no hydrogen 2.822 N/A THR 110.A OG1.A VAL 123.A O no hydrogen 3.440 N/A THR 110.A OG1.B ASP 125.A OD1 no hydrogen 3.226 N/A PHE 111.A N VAL 123.A O no hydrogen 3.409 N/A TRP 112.A NE1 SER 71.A OG no hydrogen 2.804 N/A LYS 113.A N ALA 121.A O no hydrogen 3.100 N/A LYS 113.A NZ GLU 34.A OE2 no hydrogen 3.081 N/A TRP 114.A N GLU 34.A OE1 no hydrogen 2.858 N/A TRP 114.A NE1 ILE 73.A O no hydrogen 3.020 N/A ILE 115.A N THR 119.A O no hydrogen 2.904 N/A SER 116.A OG ASN 118.A OD1 no hydrogen 3.150 N/A ASN 118.A N SER 116.A OG no hydrogen 3.125 N/A THR 119.A OG1 ASN 118.A OD1 no hydrogen 2.865 N/A VAL 120.A N.A TRP 131.A O no hydrogen 2.816 N/A VAL 120.A N.B TRP 131.A O no hydrogen 2.845 N/A ALA 121.A N LYS 113.A O no hydrogen 2.838 N/A LEU 122.A N TYR 129.A O no hydrogen 2.841 N/A VAL 123.A N PHE 111.A O no hydrogen 2.845 N/A THR 124.A N ALA 127.A O no hydrogen 2.979 N/A THR 124.A OG1 ALA 127.A O no hydrogen 3.308 N/A ASN 126.A N THR 124.A OG1 no hydrogen 3.241 N/A ALA 127.A N THR 124.A OG1 no hydrogen 3.034 N/A VAL 128.A N PHE 143.A O no hydrogen 2.930 N/A TYR 129.A N LEU 122.A O no hydrogen 2.834 N/A HIS 130.A N VAL 140.A O no hydrogen 2.862 N/A HIS 130.A NE2 TYR 157.A OH no hydrogen 2.718 N/A TRP 131.A N VAL 120.A O.A no hydrogen 2.711 N/A TRP 131.A N VAL 120.A O.B no hydrogen 2.848 N/A TRP 131.A NE1 SER 137.A O no hydrogen 3.066 N/A SER 132.A OG GLU 134.A O no hydrogen 3.527 N/A MET 133.A N ASN 118.A O no hydrogen 2.859 N/A GLU 134.A N SER 132.A OG no hydrogen 2.997 N/A VAL 140.A N HIS 130.A O no hydrogen 2.785 N/A LYS 141.A NZ ASP 144.A OD1 no hydrogen 2.731 N/A MET 142.A N VAL 128.A O no hydrogen 2.805 N/A PHE 143.A N VAL 128.A O no hydrogen 3.464 N/A ARG 145.A N ASN 126.A O no hydrogen 2.839 N/A ARG 145.A NH1 THR 124.A O no hydrogen 2.951 N/A ARG 145.A NH2 LEU 149.A O no hydrogen 3.003 N/A HIS 146.A N GLN 183.A OE1 no hydrogen 2.843 N/A HIS 146.A ND1 SER 148.A OG no hydrogen 2.735 N/A SER 148.A N HIS 146.A ND1 no hydrogen 3.080 N/A SER 148.A OG HIS 146.A ND1 no hydrogen 2.735 N/A LEU 149.A N HIS 146.A O no hydrogen 3.069 N/A ALA 150.A N SER 147.A O no hydrogen 2.977 N/A CYS 152.A N LEU 149.A O no hydrogen 3.056 N/A CYS 152.A SG LEU 149.A O no hydrogen 3.454 N/A GLN 153.A N ILE 171.A O no hydrogen 2.811 N/A ILE 155.A N THR 169.A O no hydrogen 2.823 N/A ASN 156.A N THR 169.A O no hydrogen 3.287 N/A TYR 157.A OH HIS 130.A NE2 no hydrogen 2.718 N/A ARG 158.A N LEU 167.A O no hydrogen 3.062 N/A ARG 158.A NH1 ALA 200.A O no hydrogen 2.898 N/A ARG 158.A NH1 MET 265.A O no hydrogen 2.875 N/A ARG 158.A NH2 GLN 266.A OE1 no hydrogen 2.909 N/A THR 159.A OG1 ASP 160.A O no hydrogen 2.694 N/A ASP 160.A N TRP 165.A O no hydrogen 3.078 N/A GLN 163.A N ASP 160.A O no hydrogen 3.068 N/A LYS 164.A N ASP 160.A OD1 no hydrogen 2.886 N/A LYS 164.A NZ ASP 188.A OD1 no hydrogen 2.830 N/A TRP 165.A N ASP 160.A OD1 no hydrogen 2.885 N/A LEU 166.A N TYR 185.A O no hydrogen 2.955 N/A LEU 167.A N ARG 158.A O no hydrogen 2.863 N/A LEU 168.A N GLN 183.A O no hydrogen 3.045 N/A THR 169.A N ASN 156.A O no hydrogen 3.027 N/A GLY 170.A N ALA 181.A O no hydrogen 2.854 N/A ILE 171.A N GLN 153.A O no hydrogen 2.872 N/A SER 172.A N VAL 179.A O no hydrogen 3.003 N/A GLN 174.A N ARG 177.A O no hydrogen 2.939 N/A GLN 174.A NE2 SER 172.A OG no hydrogen 2.818 N/A ARG 177.A N GLN 174.A O no hydrogen 2.958 N/A VAL 179.A N SER 172.A O no hydrogen 2.928 N/A ALA 181.A N GLY 170.A O no hydrogen 2.819 N/A MET 182.A N ILE 195.A O no hydrogen 2.794 N/A GLN 183.A N LEU 168.A O no hydrogen 2.837 N/A GLN 183.A NE2 ASP 144.A O no hydrogen 2.930 N/A GLN 183.A NE2 SER 192.A OG no hydrogen 2.889 N/A LEU 184.A N GLN 193.A O no hydrogen 2.966 N/A TYR 185.A N LEU 166.A O no hydrogen 2.768 N/A SER 186.A N VAL 191.A O no hydrogen 2.923 N/A VAL 187.A N LYS 164.A O no hydrogen 2.954 N/A ARG 189.A N SER 186.A OG no hydrogen 3.158 N/A LYS 190.A N SER 186.A O no hydrogen 2.802 N/A GLN 193.A N LEU 184.A O no hydrogen 2.761 N/A ILE 195.A N MET 182.A O no hydrogen 2.901 N/A HIS 198.A N ALA 220.A O no hydrogen 2.838 N/A HIS 198.A NE2 VAL 178.A O no hydrogen 2.864 N/A ALA 199.A N ALA 220.A O no hydrogen 3.255 N/A SER 201.A N CYS 218.A O no hydrogen 2.982 N/A SER 201.A OG PHE 202.A O no hydrogen 3.273 N/A ALA 203.A N LEU 216.A O no hydrogen 2.879 N/A GLN 204.A N GLU 269.A OE2 no hydrogen 2.854 N/A GLN 204.A NE2 THR 215.A OG1 no hydrogen 2.914 N/A PHE 205.A N SER 214.A O no hydrogen 2.939 N/A ASN 210.A N MET 207.A O no hydrogen 3.011 N/A ASN 210.A ND2 GLN 242.A O no hydrogen 3.009 N/A GLU 212.A N ASN 241.A OD1 no hydrogen 3.349 N/A SER 214.A N PHE 205.A O no hydrogen 2.730 N/A LEU 216.A N ALA 203.A O no hydrogen 2.786 N/A PHE 217.A N ILE 232.A O no hydrogen 2.824 N/A CYS 218.A N SER 201.A O no hydrogen 2.975 N/A CYS 218.A SG HIS 230.A O no hydrogen 3.531 N/A PHE 219.A N HIS 230.A O no hydrogen 3.011 N/A ALA 220.A N ALA 199.A O no hydrogen 2.805 N/A VAL 221.A N LYS 228.A O no hydrogen 2.922 N/A ARG 222.A N HIS 198.A ND1 no hydrogen 3.119 N/A ARG 222.A NH1 ALA 257.A O no hydrogen 2.803 N/A ARG 222.A NH1 ASP 260.A O no hydrogen 2.901 N/A GLY 223.A N GLY 226.A O no hydrogen 3.293 N/A GLY 226.A N GLY 223.A O no hydrogen 3.015 N/A LYS 228.A N VAL 221.A O no hydrogen 2.864 N/A LYS 228.A NZ ASP 250.A OD1 no hydrogen 2.789 N/A LEU 229.A N VAL 249.A O no hydrogen 2.818 N/A HIS 230.A N PHE 219.A O no hydrogen 2.862 N/A ILE 231.A N LYS 247.A O no hydrogen 2.907 N/A ILE 232.A N PHE 217.A O no hydrogen 2.871 N/A VAL 234.A N THR 215.A O no hydrogen 2.931 N/A ASN 241.A N PRO 238.A O no hydrogen 2.955 N/A ASN 241.A ND2 GLU 212.A O no hydrogen 2.955 N/A GLN 242.A N ASN 210.A OD1 no hydrogen 2.905 N/A PHE 244.A N GLU 233.A OE1 no hydrogen 2.841 N/A LYS 247.A N ILE 231.A O no hydrogen 2.880 N/A LYS 247.A NZ PRO 245.A O no hydrogen 2.861 N/A LYS 247.A NZ GLU 289.A O no hydrogen 2.809 N/A VAL 249.A N LEU 229.A O no hydrogen 2.903 N/A VAL 251.A N GLY 227.A O no hydrogen 3.013 N/A GLU 256.A N GLU 256.A OE1 no hydrogen 2.691 N/A ALA 257.A N PRO 254.A O no hydrogen 2.843 N/A ASP 260.A N ALA 257.A O no hydrogen 3.081 N/A PHE 261.A N ASP 260.A OD1 no hydrogen 2.925 N/A VAL 263.A N ILE 277.A O no hydrogen 2.852 N/A ALA 264.A N ILE 277.A O no hydrogen 3.218 N/A GLN 266.A N PHE 275.A O no hydrogen 3.036 N/A GLN 266.A NE2 THR 307.A OG1 no hydrogen 3.057 N/A SER 268.A N VAL 273.A O no hydrogen 2.864 N/A SER 268.A OG HIS 271.A ND1 no hydrogen 2.918 N/A SER 268.A OG ALA 314.A O no hydrogen 3.216 N/A LYS 270.A NZ GLU 332.A OE2 no hydrogen 2.820 N/A HIS 271.A N SER 268.A OG no hydrogen 3.080 N/A HIS 271.A ND1 SER 268.A OG no hydrogen 2.918 N/A HIS 271.A NE2 GLU 332.A OE2 no hydrogen 2.655 N/A VAL 273.A N SER 268.A O no hydrogen 3.148 N/A VAL 274.A N TYR 286.A O no hydrogen 2.782 N/A PHE 275.A N GLN 266.A O no hydrogen 2.834 N/A LEU 276.A N HIS 284.A O no hydrogen 2.900 N/A ILE 277.A N ALA 264.A O no hydrogen 2.921 N/A THR 278.A N TYR 282.A O no hydrogen 2.904 N/A THR 278.A OG1 ASP 260.A OD1 no hydrogen 3.209 N/A THR 278.A OG1 ASP 260.A OD2 no hydrogen 2.658 N/A LYS 279.A N PHE 261.A O no hydrogen 2.880 N/A TYR 280.A N ASP 260.A OD1 no hydrogen 2.800 N/A GLY 281.A N THR 278.A O no hydrogen 2.961 N/A TYR 282.A N THR 278.A OG1 no hydrogen 3.113 N/A ILE 283.A N ASN 297.A O no hydrogen 2.850 N/A HIS 284.A N LEU 276.A O no hydrogen 2.851 N/A HIS 284.A ND1 TYR 286.A OH no hydrogen 2.687 N/A LEU 285.A N TYR 295.A O no hydrogen 2.842 N/A TYR 286.A N VAL 274.A O no hydrogen 2.867 N/A TYR 286.A OH HIS 284.A ND1 no hydrogen 2.687 N/A ASP 287.A N THR 292.A O no hydrogen 2.846 N/A LEU 288.A N ASP 272.A O no hydrogen 2.873 N/A GLU 289.A N ASP 287.A OD1 no hydrogen 3.335 N/A THR 290.A N ASP 287.A OD2 no hydrogen 3.103 N/A THR 290.A OG1 ASP 287.A OD2 no hydrogen 2.623 N/A THR 290.A OG1 THR 292.A OG1 no hydrogen 2.782 N/A GLY 291.A N ASP 287.A O no hydrogen 2.773 N/A THR 292.A N THR 290.A OG1 no hydrogen 3.078 N/A THR 292.A OG1 THR 290.A OG1 no hydrogen 2.782 N/A CYS 293.A SG LEU 285.A O no hydrogen 3.899 N/A ILE 294.A N LEU 285.A O no hydrogen 2.816 N/A ASN 297.A N ILE 283.A O no hydrogen 2.957 N/A ARG 298.A NE TYR 280.A O no hydrogen 2.883 N/A ARG 298.A NH2 TYR 280.A O no hydrogen 3.020 N/A ILE 299.A N GLY 281.A O no hydrogen 2.931 N/A SER 300.A OG GLU 302.A O no hydrogen 2.621 N/A GLU 302.A N SER 300.A OG no hydrogen 3.272 N/A THR 303.A OG1.A LYS 279.A O no hydrogen 3.371 N/A PHE 305.A N VAL 319.A O no hydrogen 3.086 N/A ALA 308.A N ILE 317.A O no hydrogen 2.888 N/A HIS 310.A N GLY 315.A O no hydrogen 2.900 N/A GLU 311.A N ASP 36.A OD2 no hydrogen 2.748 N/A ALA 314.A N GLU 311.A O no hydrogen 3.293 N/A GLY 315.A N HIS 310.A O no hydrogen 2.984 N/A ILE 316.A N VAL 328.A O no hydrogen 2.859 N/A ILE 317.A N ALA 308.A O no hydrogen 2.920 N/A GLY 318.A N LEU 326.A O no hydrogen 2.846 N/A VAL 319.A N VAL 306.A O no hydrogen 3.126 N/A ASN 320.A N GLN 324.A O no hydrogen 2.983 N/A ASN 320.A ND2 SER 300.A OG no hydrogen 2.960 N/A ARG 321.A N THR 303.A O.A no hydrogen 3.043 N/A ARG 321.A N THR 303.A O.B no hydrogen 2.997 N/A LYS 322.A N ASN 320.A OD1 no hydrogen 3.019 N/A LYS 322.A NZ GLU 302.A OE2 no hydrogen 3.099 N/A GLY 323.A N ASN 320.A O no hydrogen 2.893 N/A GLN 324.A N ASN 320.A OD1 no hydrogen 3.068 N/A GLN 324.A NE2 GLU 12.A OE1 no hydrogen 2.757 N/A VAL 325.A N LEU 14.A O no hydrogen 2.943 N/A LEU 326.A N GLY 318.A O no hydrogen 2.928 N/A SER 327.A N GLN 11.A O no hydrogen 2.798 N/A SER 327.A OG HIS 13.A NE2 no hydrogen 2.663 N/A SER 327.A OG HIS 310.A ND1 no hydrogen 3.402 N/A VAL 328.A N ILE 316.A O no hydrogen 2.908 N/A CYS 329.A N ARG 9.A O no hydrogen 3.056 N/A CYS 329.A SG VAL 330.A O no hydrogen 3.657 N/A GLU 331.A N PRO 7.A O no hydrogen 2.940 N/A ASN 334.A N GLU 331.A O no hydrogen 3.251 N/A ASN 334.A N GLU 331.A OE1 no hydrogen 2.821 N/A ILE 335.A N GLU 331.A O no hydrogen 2.996 N/A TYR 338.A N ASN 334.A O no hydrogen 3.030 N/A ILE 339.A N ILE 335.A O no hydrogen 2.894 N/A THR 340.A N ILE 336.A O no hydrogen 2.917 N/A THR 340.A OG1 ILE 336.A O no hydrogen 2.871 N/A ASN 341.A N PRO 337.A O no hydrogen 3.051 N/A ASN 341.A ND2 PRO 337.A O no hydrogen 3.082 N/A VAL 342.A N TYR 338.A O no hydrogen 2.861 N/A LEU 343.A N TYR 338.A O no hydrogen 3.147 N/A ASN 345.A N ILE 339.A O no hydrogen 3.007 N/A LEU 348.A N ASN 345.A OD1 no hydrogen 2.945 N/A ALA 349.A N ASN 345.A O no hydrogen 3.074 N/A LEU 350.A N PRO 346.A O no hydrogen 2.873 N/A ARG 351.A N ASP 347.A O no hydrogen 2.960 N/A ARG 351.A NH2 ASP 287.A OD2 no hydrogen 3.126 N/A MET 352.A N LEU 348.A O no hydrogen 2.910 N/A ALA 353.A N ALA 349.A O no hydrogen 3.058 N/A VAL 354.A N LEU 350.A O no hydrogen 2.831 N/A ARG 355.A N ARG 351.A O no hydrogen 3.125 N/A ASN 356.A N MET 352.A O no hydrogen 2.886 N/A ASN 357.A N ALA 353.A O no hydrogen 2.960 N/A LEU 358.A N VAL 354.A O no hydrogen 3.180 N/A