Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2y8o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NH2 PRO 89.A O no hydrogen 2.781 N/A TYR 6.A N VAL 17.A O no hydrogen 2.929 N/A TYR 6.A OH TYR 21.A O no hydrogen 2.743 N/A GLN 8.A N TRP 15.A O no hydrogen 2.922 N/A LEU 10.A N THR 13.A O no hydrogen 2.887 N/A THR 13.A N LEU 10.A O no hydrogen 3.186 N/A THR 13.A OG1 ASN 11.A O no hydrogen 3.173 N/A TRP 15.A N GLN 8.A O no hydrogen 2.804 N/A GLU 16.A N TYR 100.A OH no hydrogen 3.036 N/A VAL 17.A N TYR 6.A O no hydrogen 3.168 N/A GLU 19.A N THR 4.A O no hydrogen 2.860 N/A ARG 20.A NE ASP 40.A OD1 no hydrogen 2.981 N/A ARG 20.A NH2 ASP 40.A OD1 no hydrogen 3.433 N/A ARG 20.A NH2 ASP 40.A OD2 no hydrogen 2.862 N/A TYR 21.A N PRO 18.A O no hydrogen 3.001 N/A TYR 21.A OH ASP 85.A OD2 no hydrogen 2.750 N/A GLN 22.A N PHE 39.A O no hydrogen 2.954 N/A GLN 22.A NE2 GLU 19.A O no hydrogen 2.875 N/A SER 25.A N ALA 37.A O no hydrogen 2.838 N/A VAL 27.A N VAL 35.A O no hydrogen 2.954 N/A GLY 30.A N GLY 33.A O no hydrogen 3.132 N/A VAL 35.A N GLY 28.A O no hydrogen 2.965 N/A CYS 36.A N VAL 49.A O no hydrogen 2.950 N/A ALA 37.A N SER 25.A O no hydrogen 2.844 N/A ALA 38.A N VAL 47.A O no hydrogen 2.817 N/A PHE 39.A N GLN 22.A O no hydrogen 2.866 N/A ASP 40.A N LEU 45.A O no hydrogen 2.855 N/A THR 41.A N ARG 20.A O no hydrogen 2.947 N/A THR 41.A OG1 ARG 20.A O no hydrogen 2.993 N/A LYS 42.A N ASP 40.A OD1 no hydrogen 2.896 N/A THR 43.A N ASP 40.A OD1 no hydrogen 3.475 N/A THR 43.A OG1 ASP 40.A OD2 no hydrogen 2.835 N/A GLY 44.A N ASP 40.A O no hydrogen 2.725 N/A LEU 45.A N THR 43.A OG1 no hydrogen 3.241 N/A VAL 47.A N ALA 38.A O no hydrogen 2.801 N/A ALA 48.A N THR 103.A O no hydrogen 2.856 N/A VAL 49.A N CYS 36.A O no hydrogen 2.858 N/A LYS 50.A N LEU 101.A O no hydrogen 2.847 N/A LYS 50.A NZ GLU 68.A OE2 no hydrogen 3.006 N/A LYS 51.A N SER 34.A O no hydrogen 2.821 N/A LYS 51.A NZ ILE 14.A O no hydrogen 2.691 N/A LEU 52.A N VAL 99.A O no hydrogen 3.085 N/A SER 53.A N TYR 32.A O no hydrogen 3.330 N/A SER 53.A OG ALA 31.A O no hydrogen 2.973 N/A GLN 57.A N ARG 54.A O no hydrogen 3.283 N/A SER 58.A OG HIS 61.A ND1 no hydrogen 3.133 N/A HIS 61.A N SER 58.A OG no hydrogen 3.165 N/A ALA 62.A N SER 58.A O no hydrogen 2.890 N/A LYS 63.A N ILE 59.A O no hydrogen 2.895 N/A LYS 63.A NZ GLU 314.A O no hydrogen 2.755 N/A ARG 64.A N ILE 60.A O no hydrogen 3.081 N/A THR 65.A N HIS 61.A O no hydrogen 2.925 N/A THR 65.A OG1 PRO 55.A O no hydrogen 2.933 N/A THR 65.A OG1 HIS 61.A O no hydrogen 2.974 N/A TYR 66.A N ALA 62.A O no hydrogen 3.073 N/A ARG 67.A N LYS 63.A O no hydrogen 2.831 N/A ARG 67.A NE GLU 314.A OE1 no hydrogen 3.500 N/A ARG 67.A NE GLU 314.A OE2 no hydrogen 2.739 N/A ARG 67.A NH1 LEU 168.A O no hydrogen 3.089 N/A ARG 67.A NH2 GLU 314.A OE1 no hydrogen 2.965 N/A GLU 68.A N ARG 64.A O no hydrogen 2.891 N/A LEU 69.A N THR 65.A O no hydrogen 3.018 N/A ARG 70.A N TYR 66.A O no hydrogen 2.876 N/A ARG 70.A NH1 TYR 66.A OH no hydrogen 3.058 N/A ARG 70.A NH2 ASP 310.A O no hydrogen 2.890 N/A LEU 71.A N ARG 67.A O no hydrogen 3.039 N/A LEU 72.A N GLU 68.A O no hydrogen 2.886 N/A LYS 73.A N LEU 69.A O no hydrogen 2.892 N/A LYS 73.A NZ GLU 330.A O no hydrogen 2.838 N/A LYS 73.A NZ GLU 330.A OE1 no hydrogen 2.822 N/A HIS 74.A N ARG 70.A O no hydrogen 3.235 N/A HIS 74.A N LEU 71.A O no hydrogen 3.041 N/A HIS 74.A NE2 ASP 307.A O no hydrogen 2.770 N/A MET 75.A N LEU 71.A O no hydrogen 3.308 N/A LYS 76.A N TYR 137.A OH no hydrogen 2.855 N/A ASN 79.A N HIS 77.A ND1 no hydrogen 2.881 N/A ASN 79.A ND2 LEU 161.A O no hydrogen 3.014 N/A VAL 80.A N HIS 77.A O no hydrogen 3.142 N/A ILE 81.A N ILE 163.A O no hydrogen 2.951 N/A LEU 84.A N VAL 102.A O no hydrogen 2.811 N/A ASP 85.A N VAL 102.A O no hydrogen 3.293 N/A PHE 87.A N TYR 100.A O no hydrogen 3.060 N/A THR 88.A OG1 ASP 98.A O no hydrogen 2.807 N/A ALA 90.A N THR 88.A OG1 no hydrogen 3.148 N/A ARG 91.A N GLU 95.A OE2 no hydrogen 2.903 N/A GLU 95.A N SER 92.A O no hydrogen 3.076 N/A GLU 95.A N SER 92.A OG no hydrogen 3.329 N/A PHE 96.A N LEU 93.A O no hydrogen 3.040 N/A TYR 100.A N PHE 87.A O no hydrogen 2.957 N/A LEU 101.A N LYS 50.A O no hydrogen 2.870 N/A VAL 102.A N ASP 85.A O no hydrogen 2.803 N/A THR 103.A N ALA 48.A O no hydrogen 3.072 N/A HIS 104.A ND1 ARG 46.A O no hydrogen 3.280 N/A LEU 105.A N ARG 46.A O no hydrogen 2.995 N/A ALA 108.A N VAL 155.A O no hydrogen 2.901 N/A LEU 110.A N PRO 150.A O no hydrogen 3.296 N/A ASN 112.A N ASP 109.A OD1 no hydrogen 2.948 N/A ILE 113.A N ASP 109.A O no hydrogen 3.062 N/A VAL 114.A N LEU 110.A O no hydrogen 3.035 N/A LYS 115.A N ASN 111.A O no hydrogen 2.994 N/A CYS 116.A N ILE 113.A O no hydrogen 3.116 N/A CYS 116.A SG.A ASN 112.A O no hydrogen 3.525 N/A CYS 116.A SG.B ASN 112.A O no hydrogen 3.321 N/A CYS 116.A SG.B ILE 113.A O no hydrogen 3.505 N/A GLN 117.A NE2 ILE 113.A O no hydrogen 2.971 N/A THR 120.A N HIS 123.A ND1 no hydrogen 2.906 N/A THR 120.A OG1 HIS 123.A ND1 no hydrogen 3.250 N/A HIS 123.A N THR 120.A OG1 no hydrogen 3.175 N/A VAL 124.A N THR 120.A O no hydrogen 3.077 N/A GLN 125.A N ASP 121.A O no hydrogen 2.949 N/A GLN 125.A NE2 ASP 121.A OD2 no hydrogen 2.777 N/A PHE 126.A N ASP 122.A O no hydrogen 3.044 N/A LEU 127.A N HIS 123.A O no hydrogen 2.857 N/A ILE 128.A N VAL 124.A O no hydrogen 2.902 N/A TYR 129.A N GLN 125.A O no hydrogen 2.898 N/A TYR 129.A OH GLU 303.A OE2 no hydrogen 2.712 N/A GLN 130.A N PHE 126.A O no hydrogen 3.067 N/A GLN 130.A NE2 PHE 126.A O no hydrogen 3.234 N/A GLN 130.A NE2 SER 159.A O no hydrogen 2.763 N/A ILE 131.A N LEU 127.A O no hydrogen 3.075 N/A LEU 132.A N ILE 128.A O no hydrogen 2.957 N/A ARG 133.A N TYR 129.A O no hydrogen 2.832 N/A ARG 133.A NE ASP 302.A O no hydrogen 2.828 N/A ARG 133.A NH1 GLU 78.A OE1 no hydrogen 3.002 N/A ARG 133.A NH1 ASN 79.A OD1 no hydrogen 2.880 N/A ARG 133.A NH2 GLU 78.A OE1 no hydrogen 3.315 N/A ARG 133.A NH2 ASP 302.A O no hydrogen 2.934 N/A ARG 133.A NH2 ASP 302.A OD1 no hydrogen 3.130 N/A GLY 134.A N GLN 130.A O no hydrogen 2.938 N/A LEU 135.A N ILE 131.A O no hydrogen 2.873 N/A LYS 136.A N LEU 132.A O no hydrogen 2.816 N/A LYS 136.A NZ GLU 303.A O no hydrogen 2.770 N/A TYR 137.A N ARG 133.A O no hydrogen 3.330 N/A TYR 137.A OH HIS 74.A O no hydrogen 3.267 N/A ILE 138.A N GLY 134.A O no hydrogen 2.942 N/A HIS 139.A N LEU 135.A O no hydrogen 2.755 N/A HIS 139.A NE2 ASP 191.A OD2 no hydrogen 2.794 N/A SER 140.A N LYS 136.A O no hydrogen 3.048 N/A SER 140.A N TYR 137.A O no hydrogen 3.237 N/A SER 140.A OG LYS 136.A O no hydrogen 3.442 N/A SER 140.A OG TYR 137.A O no hydrogen 2.635 N/A ALA 141.A N ILE 138.A O no hydrogen 3.009 N/A ASP 142.A N HIS 139.A O no hydrogen 2.876 N/A ILE 143.A N ILE 138.A O no hydrogen 3.159 N/A HIS 145.A N ASP 191.A OD2 no hydrogen 2.845 N/A HIS 145.A NE2 LEU 164.A O no hydrogen 2.844 N/A ARG 146.A N ASP 191.A OD1 no hydrogen 2.887 N/A ARG 146.A NE ILE 144.A O no hydrogen 3.422 N/A ASP 147.A N HIS 145.A ND1 no hydrogen 3.023 N/A ASN 152.A N LYS 149.A O no hydrogen 2.852 N/A ASN 152.A ND2 ASP 147.A O no hydrogen 2.864 N/A ASN 152.A ND2 ASP 147.A OD2 no hydrogen 3.483 N/A LEU 153.A N PRO 150.A O no hydrogen 3.186 N/A ALA 154.A N LYS 162.A O no hydrogen 2.938 N/A VAL 155.A N ALA 108.A O no hydrogen 2.730 N/A ASN 156.A N GLU 160.A O no hydrogen 3.095 N/A ASN 156.A ND2 GLU 160.A OE1 no hydrogen 3.005 N/A ASP 158.A N ASN 156.A OD1 no hydrogen 2.870 N/A SER 159.A N ASN 156.A O no hydrogen 2.882 N/A GLU 160.A N ASN 156.A OD1 no hydrogen 3.044 N/A LEU 161.A N GLN 130.A OE1 no hydrogen 2.842 N/A LYS 162.A N ALA 154.A O no hydrogen 2.944 N/A LYS 162.A NZ GLU 78.A O no hydrogen 3.012 N/A ILE 163.A N ASN 79.A O no hydrogen 2.841 N/A LEU 164.A N ASN 152.A O no hydrogen 2.988 N/A GLY 167.A N HIS 145.A O no hydrogen 2.927 N/A ARG 170.A NH1 GLY 167.A O no hydrogen 3.279 N/A ARG 170.A NH1 ALA 169.A O no hydrogen 2.985 N/A ARG 172.A NE GLN 217.A OE1 no hydrogen 2.933 N/A ARG 172.A NH2 GLN 217.A OE1 no hydrogen 3.220 N/A TRP 173.A NE1 GLY 211.A O no hydrogen 3.108 N/A TYR 174.A OH GLU 201.A OE1 no hydrogen 2.519 N/A TYR 174.A OH GLU 201.A OE2 no hydrogen 3.360 N/A ARG 175.A N ARG 172.A O no hydrogen 3.232 N/A ARG 175.A NH2 ARG 146.A O no hydrogen 2.994 N/A GLU 178.A N GLU 178.A OE1 no hydrogen 2.938 N/A ILE 179.A N ALA 176.A O no hydrogen 3.200 N/A MET 180.A N ALA 176.A O no hydrogen 3.089 N/A LEU 181.A N PRO 177.A O no hydrogen 3.281 N/A ASN 182.A N ILE 179.A O no hydrogen 3.208 N/A TRP 183.A N GLU 178.A O no hydrogen 2.763 N/A ASN 187.A ND2.A SER 279.A OG no hydrogen 2.899 N/A ASN 187.A ND2.B THR 189.A OG1 no hydrogen 2.638 N/A THR 189.A N ASN 187.A OD1.B no hydrogen 2.999 N/A THR 189.A OG1 ASN 187.A OD1.A no hydrogen 2.796 N/A THR 189.A OG1 SER 279.A O no hydrogen 2.958 N/A VAL 190.A N ASN 187.A O no hydrogen 3.168 N/A ASP 191.A N GLN 188.A O no hydrogen 3.057 N/A TRP 193.A N THR 189.A O no hydrogen 3.123 N/A SER 194.A N VAL 190.A O no hydrogen 3.246 N/A SER 194.A OG TYR 174.A O no hydrogen 2.631 N/A SER 194.A OG VAL 190.A O no hydrogen 3.283 N/A VAL 195.A N ASP 191.A O no hydrogen 3.011 N/A GLY 196.A N ILE 192.A O no hydrogen 2.987 N/A CYS 197.A N TRP 193.A O no hydrogen 3.001 N/A CYS 197.A SG TRP 173.A O no hydrogen 3.946 N/A CYS 197.A SG TRP 193.A O no hydrogen 3.519 N/A ILE 198.A N SER 194.A O no hydrogen 2.897 N/A MET 199.A N VAL 195.A O no hydrogen 2.809 N/A ALA 200.A N GLY 196.A O no hydrogen 2.959 N/A GLU 201.A N CYS 197.A O no hydrogen 3.259 N/A LEU 202.A N ILE 198.A O no hydrogen 2.968 N/A LEU 203.A N MET 199.A O no hydrogen 2.959 N/A THR 204.A N ALA 200.A O no hydrogen 2.945 N/A THR 204.A OG1 ALA 200.A O no hydrogen 3.064 N/A GLY 205.A N GLU 201.A O no hydrogen 2.903 N/A ARG 206.A N THR 204.A OG1 no hydrogen 3.159 N/A GLY 211.A N PHE 209.A O no hydrogen 2.880 N/A THR 212.A N ASP 216.A OD2 no hydrogen 2.889 N/A THR 212.A OG1 ASP 216.A OD2 no hydrogen 3.214 N/A ASP 216.A N ASP 213.A OD1 no hydrogen 2.982 N/A GLN 217.A N ASP 213.A O no hydrogen 2.933 N/A GLN 217.A NE2 ARG 172.A O no hydrogen 2.971 N/A LEU 218.A N HIS 214.A O no hydrogen 2.994 N/A LYS 219.A N ILE 215.A O no hydrogen 2.977 N/A LEU 220.A N ASP 216.A O no hydrogen 3.116 N/A ILE 221.A N GLN 217.A O no hydrogen 2.962 N/A LEU 222.A N LEU 218.A O no hydrogen 2.795 N/A ARG 223.A N LYS 219.A O no hydrogen 3.027 N/A LEU 224.A N ILE 221.A O no hydrogen 3.117 N/A VAL 225.A N ILE 221.A O no hydrogen 3.040 N/A GLY 226.A N LEU 222.A O no hydrogen 2.703 N/A THR 227.A N MET 251.A O no hydrogen 3.085 N/A LEU 233.A N GLY 229.A O no hydrogen 3.096 N/A LYS 234.A N ALA 230.A O no hydrogen 3.118 N/A LYS 235.A N LEU 232.A O no hydrogen 2.933 N/A LYS 235.A NZ ASP 278.A OD1 no hydrogen 3.272 N/A LYS 235.A NZ ASP 278.A OD2 no hydrogen 2.826 N/A LYS 235.A NZ ASP 280.A OD2 no hydrogen 3.019 N/A ILE 236.A N LEU 233.A O no hydrogen 3.043 N/A SER 237.A N TRP 183.A O no hydrogen 3.302 N/A ALA 241.A N SER 238.A OG no hydrogen 2.988 N/A ARG 242.A N SER 238.A O no hydrogen 3.019 N/A ARG 242.A NE ILE 236.A O no hydrogen 2.953 N/A ARG 242.A NH2 ILE 236.A O no hydrogen 3.269 N/A ASN 243.A N GLU 239.A O no hydrogen 2.867 N/A TYR 244.A N SER 240.A O no hydrogen 2.836 N/A ILE 245.A N ALA 241.A O no hydrogen 2.950 N/A GLN 246.A N ARG 242.A O no hydrogen 3.017 N/A SER 247.A N TYR 244.A O no hydrogen 2.859 N/A SER 247.A OG TYR 244.A O no hydrogen 2.704 N/A LEU 248.A N ILE 245.A O no hydrogen 3.114 N/A MET 251.A N THR 227.A OG1 no hydrogen 3.113 N/A LYS 253.A NZ MET 254.A O no hydrogen 2.923 N/A LYS 253.A NZ GLU 272.A OE1 no hydrogen 2.885 N/A LYS 253.A NZ GLU 272.A OE2 no hydrogen 3.561 N/A MET 254.A N LEU 224.A O no hydrogen 2.926 N/A PHE 256.A N GLU 272.A OE2 no hydrogen 3.337 N/A ALA 257.A N ASN 255.A OD1 no hydrogen 2.993 N/A ASN 258.A N ASN 255.A O no hydrogen 3.078 N/A PHE 260.A N PHE 256.A O no hydrogen 2.861 N/A ALA 263.A N PHE 260.A O no hydrogen 3.241 N/A ASN 264.A ND2 ASP 121.A OD2 no hydrogen 3.070 N/A LEU 266.A N ASN 264.A OD1 no hydrogen 2.887 N/A VAL 268.A N ASN 264.A O no hydrogen 3.032 N/A ASP 269.A N PRO 265.A O no hydrogen 2.872 N/A LEU 270.A N LEU 266.A O no hydrogen 3.030 N/A LEU 271.A N ALA 267.A O no hydrogen 2.949 N/A GLU 272.A N VAL 268.A O no hydrogen 2.998 N/A LYS 273.A N ASP 269.A O no hydrogen 3.207 N/A MET 274.A N LEU 270.A O no hydrogen 2.962 N/A MET 274.A N LEU 271.A O no hydrogen 3.062 N/A LEU 275.A N LEU 271.A O no hydrogen 2.884 N/A ASP 280.A N ASP 278.A OD1 no hydrogen 3.053 N/A LYS 281.A N ASP 278.A O no hydrogen 2.976 N/A LYS 281.A NZ GLU 231.A OE1 no hydrogen 2.885 N/A ARG 282.A N SER 279.A O no hydrogen 3.261 N/A ARG 282.A NE VAL 276.A O no hydrogen 2.742 N/A ARG 282.A NH1 GLU 178.A OE2 no hydrogen 2.894 N/A ARG 282.A NH1 THR 189.A O no hydrogen 3.124 N/A ARG 282.A NH2 GLU 178.A OE1 no hydrogen 2.802 N/A ARG 282.A NH2 GLU 178.A OE2 no hydrogen 3.440 N/A ARG 282.A NH2 VAL 276.A O no hydrogen 3.519 N/A ARG 282.A NH2 LEU 277.A O no hydrogen 3.112 N/A ILE 283.A N LYS 273.A O no hydrogen 3.050 N/A THR 284.A N GLN 287.A OE1 no hydrogen 3.032 N/A GLN 287.A N THR 284.A OG1 no hydrogen 3.091 N/A ALA 288.A N THR 284.A O no hydrogen 2.894 N/A LEU 289.A N ALA 285.A O no hydrogen 3.119 N/A ALA 290.A N GLN 287.A O no hydrogen 3.105 N/A HIS 291.A N ALA 288.A O no hydrogen 2.904 N/A HIS 291.A NE2 ASP 269.A OD2 no hydrogen 2.817 N/A TYR 293.A N HIS 291.A ND1 no hydrogen 2.946 N/A TYR 293.A OH ASP 121.A OD1 no hydrogen 2.816 N/A PHE 294.A N HIS 291.A O no hydrogen 3.036 N/A ALA 295.A N ALA 292.A O no hydrogen 3.064 N/A GLN 296.A NE2 ASP 122.A OD1.A no hydrogen 3.191 N/A GLN 296.A NE2 GLN 125.A OE1 no hydrogen 2.738 N/A TYR 297.A N PHE 294.A O no hydrogen 2.809 N/A TYR 297.A OH ASP 122.A OD1.B no hydrogen 2.529 N/A HIS 298.A N PHE 294.A O no hydrogen 2.914 N/A HIS 298.A ND1 GLU 303.A OE2 no hydrogen 2.572 N/A ASP 299.A N GLU 303.A OE2 no hydrogen 3.054 N/A ASP 301.A N ASP 299.A OD1 no hydrogen 3.022 N/A ASP 302.A N ASP 299.A O no hydrogen 2.828 N/A ALA 306.A N SER 140.A OG no hydrogen 2.824 N/A GLN 311.A NE2 ASP 142.A O no hydrogen 3.035 N/A SER 312.A N ASP 310.A OD1 no hydrogen 2.818 N/A SER 312.A OG ASP 310.A OD1 no hydrogen 2.657 N/A GLU 314.A N GLN 311.A O no hydrogen 2.948 N/A SER 315.A N SER 312.A O no hydrogen 3.095 N/A SER 315.A OG SER 312.A O no hydrogen 3.295 N/A ARG 316.A N PHE 313.A O no hydrogen 2.939 N/A LEU 319.A N GLU 322.A OE1 no hydrogen 2.857 N/A TRP 323.A N LEU 319.A O no hydrogen 3.026 N/A LYS 324.A N ILE 320.A O no hydrogen 2.932 N/A LYS 324.A NZ PHE 96.A O no hydrogen 2.688 N/A SER 325.A N ASP 321.A O no hydrogen 2.857 N/A LEU 326.A N GLU 322.A O no hydrogen 2.962 N/A THR 327.A N TRP 323.A O no hydrogen 2.907 N/A THR 327.A OG1 TRP 323.A O no hydrogen 2.916 N/A TYR 328.A N LYS 324.A O no hydrogen 2.907 N/A ASP 329.A N SER 325.A O no hydrogen 3.001 N/A GLU 330.A N LEU 326.A O no hydrogen 3.112 N/A VAL 331.A N THR 327.A O no hydrogen 2.944 N/A ILE 332.A N TYR 328.A O no hydrogen 2.933 N/A SER 333.A N ASP 329.A O no hydrogen 2.918 N/A SER 333.A OG ASP 329.A O no hydrogen 3.136 N/A SER 333.A OG GLU 330.A O no hydrogen 3.438 N/A PHE 334.A N VAL 331.A O no hydrogen 3.204 N/A