Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2z4e_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 6.A N ASP 3.A O no hydrogen 2.876 N/A ARG 7.A NE ASP 3.A O no hydrogen 3.012 N/A ARG 7.A NH2 ASP 3.A O no hydrogen 2.657 N/A LEU 9.A N SER 5.A O no hydrogen 3.272 N/A GLN 10.A N ILE 6.A O no hydrogen 3.167 N/A GLU 11.A N ARG 7.A O no hydrogen 2.825 N/A ILE 12.A N TYR 8.A O no hydrogen 3.248 N/A TYR 13.A N LEU 9.A O no hydrogen 2.565 N/A ASN 14.A N GLN 10.A O no hydrogen 2.908 N/A ASN 14.A ND2 GLN 10.A OE1 no hydrogen 3.613 N/A SER 15.A N GLU 11.A O no hydrogen 2.526 N/A ASN 16.A N ILE 12.A O no hydrogen 2.798 N/A ASN 17.A N TYR 13.A O no hydrogen 3.091 N/A ASN 17.A N ASN 14.A O no hydrogen 3.049 N/A GLN 18.A N ASN 14.A O no hydrogen 3.052 N/A GLN 18.A N SER 15.A O no hydrogen 3.012 N/A LYS 19.A N SER 15.A O no hydrogen 2.997 N/A ILE 20.A N ASN 16.A O no hydrogen 2.857 N/A VAL 21.A N ASN 17.A O no hydrogen 3.273 N/A ASN 22.A N GLN 18.A O no hydrogen 2.969 N/A LEU 23.A N LYS 19.A O no hydrogen 2.899 N/A LYS 24.A N ILE 20.A O no hydrogen 3.080 N/A GLU 25.A N ASN 22.A O no hydrogen 3.116 N/A LYS 26.A N ASN 22.A O no hydrogen 3.082 N/A VAL 27.A N LEU 23.A O no hydrogen 2.908 N/A VAL 27.A N LYS 24.A O no hydrogen 3.215 N/A ALA 28.A N LYS 24.A O no hydrogen 2.888 N/A GLN 29.A N GLU 25.A O no hydrogen 3.087 N/A LEU 30.A N LYS 26.A O no hydrogen 3.392 N/A GLU 31.A N VAL 27.A O no hydrogen 2.995 N/A ALA 32.A N GLN 29.A O no hydrogen 3.077 N/A GLN 33.A N GLN 29.A O no hydrogen 3.316 N/A GLN 33.A N LEU 30.A O no hydrogen 2.590 N/A CYS 34.A N LEU 30.A O no hydrogen 3.116 N/A CYS 34.A SG LEU 30.A O no hydrogen 3.832 N/A VAL 42.A N ASP 40.A OD2 no hydrogen 3.421 N/A HIS 45.A N LEU 65.A O no hydrogen 2.888 N/A LYS 50.A N ASP 54.A OD1 no hydrogen 2.833 N/A CYS 52.A N THR 91.A OG1 no hydrogen 3.164 N/A CYS 52.A SG TYR 80.A O no hydrogen 4.007 N/A CYS 52.A SG TRP 90.A O no hydrogen 3.184 N/A CYS 52.A SG THR 91.A OG1 no hydrogen 3.111 N/A GLN 53.A NE2 GLN 53.A O no hydrogen 2.959 N/A GLN 53.A NE2 ASN 57.A OD1 no hydrogen 2.809 N/A GLN 53.A NE2 GLY 87.A O no hydrogen 3.434 N/A ASP 54.A N ASP 51.A OD1 no hydrogen 2.570 N/A ILE 55.A N ASP 51.A O no hydrogen 3.307 N/A ALA 56.A N CYS 52.A O no hydrogen 2.816 N/A ASN 57.A N GLN 53.A O no hydrogen 2.709 N/A LYS 58.A N ILE 55.A O no hydrogen 3.053 N/A LYS 58.A NZ THR 48.A O no hydrogen 2.856 N/A GLY 59.A N ALA 56.A O no hydrogen 2.901 N/A ALA 60.A N ILE 55.A O no hydrogen 3.426 N/A GLN 62.A NE2 GLN 62.A O no hydrogen 3.411 N/A GLN 62.A NE2 TYR 66.A OH no hydrogen 3.054 N/A SER 63.A OG ILE 83.A O no hydrogen 3.334 N/A GLY 64.A N CYS 81.A O no hydrogen 3.140 N/A TYR 66.A N VAL 79.A O no hydrogen 3.120 N/A TYR 66.A OH GLN 62.A O no hydrogen 2.560 N/A ILE 68.A N PHE 77.A O no hydrogen 2.836 N/A LYS 69.A N GLY 49.A O no hydrogen 2.966 N/A LYS 69.A NZ ALA 73.A O no hydrogen 2.565 N/A LYS 72.A NZ GLN 138.A O no hydrogen 3.455 N/A ALA 73.A N PRO 70.A O no hydrogen 2.935 N/A PHE 77.A N ILE 68.A O no hydrogen 2.997 N/A VAL 79.A N TYR 66.A O no hydrogen 2.962 N/A CYS 81.A N GLY 64.A O no hydrogen 2.865 N/A GLU 82.A N TRP 90.A O no hydrogen 2.817 N/A ILE 83.A N SER 63.A OG no hydrogen 2.929 N/A ASP 84.A N ASN 88.A O no hydrogen 3.047 N/A GLY 87.A N ASP 84.A O no hydrogen 3.463 N/A ASN 88.A N ASP 84.A OD2 no hydrogen 2.600 N/A ASN 88.A ND2 ASP 84.A OD1 no hydrogen 2.896 N/A GLY 89.A N GLN 53.A OE1 no hydrogen 3.028 N/A TRP 90.A N GLU 82.A O no hydrogen 2.581 N/A THR 91.A N ILE 285.A O no hydrogen 2.983 N/A VAL 92.A N TYR 80.A O no hydrogen 3.264 N/A PHE 93.A N MET 283.A O no hydrogen 2.802 N/A GLN 94.A NE2 ASN 244.A OD1 no hydrogen 3.048 N/A LYS 95.A N PHE 125.A O no hydrogen 3.200 N/A LYS 95.A NZ THR 282.A OG1 no hydrogen 2.644 N/A ARG 96.A N THR 281.A O no hydrogen 2.832 N/A ARG 96.A NE GLU 124.A OE2 no hydrogen 3.316 N/A ARG 96.A NH1 LEU 243.A O no hydrogen 2.975 N/A ARG 96.A NH1 GLY 245.A O no hydrogen 2.871 N/A ARG 96.A NH2 GLY 245.A O no hydrogen 2.835 N/A LEU 97.A N GLU 124.A OE2 no hydrogen 3.096 N/A SER 100.A N ASP 98.A OD1 no hydrogen 2.701 N/A SER 100.A OG ASP 98.A OD1 no hydrogen 2.619 N/A SER 100.A OG GLU 124.A OE1 no hydrogen 3.310 N/A VAL 101.A N GLU 124.A OE1 no hydrogen 2.833 N/A LYS 104.A N ASP 102.A OD2 no hydrogen 2.888 N/A LYS 105.A N PHE 103.A O no hydrogen 2.889 N/A ASN 106.A N GLN 109.A OE1 no hydrogen 3.200 N/A TRP 107.A N ASP 215.A OD1 no hydrogen 3.025 N/A TRP 107.A NE1 GLU 169.A OE2 no hydrogen 2.986 N/A GLN 109.A N ASN 106.A OD1 no hydrogen 2.862 N/A TYR 110.A N ASN 106.A O no hydrogen 2.999 N/A TYR 110.A OH PHE 103.A O no hydrogen 2.508 N/A LYS 111.A N TRP 107.A O no hydrogen 2.908 N/A LYS 111.A NZ GLU 169.A OE1 no hydrogen 2.818 N/A LYS 111.A NZ TYR 173.A OH no hydrogen 3.477 N/A GLU 112.A N ILE 108.A O no hydrogen 2.816 N/A GLY 113.A N GLN 109.A O no hydrogen 2.828 N/A PHE 114.A N TRP 126.A O no hydrogen 2.914 N/A HIS 116.A N GLU 124.A O no hydrogen 3.000 N/A THR 120.A OG1 THR 122.A OG1 no hydrogen 2.878 N/A GLY 121.A N SER 118.A O no hydrogen 3.228 N/A THR 122.A N SER 118.A OG no hydrogen 3.099 N/A THR 122.A OG1 THR 120.A OG1 no hydrogen 2.878 N/A PHE 125.A N LYS 95.A O no hydrogen 3.448 N/A TRP 126.A N PHE 114.A O no hydrogen 2.761 N/A TRP 126.A NE1 TYR 110.A O no hydrogen 2.820 N/A LEU 127.A N PHE 93.A O no hydrogen 3.032 N/A ASN 129.A N TYR 110.A O no hydrogen 2.764 N/A GLU 130.A N LYS 111.A O no hydrogen 3.079 N/A LYS 131.A NZ GLU 112.A O no hydrogen 3.224 N/A ILE 132.A N GLY 128.A O no hydrogen 3.099 N/A HIS 133.A N ASN 129.A O no hydrogen 2.813 N/A HIS 133.A ND1 VAL 166.A O no hydrogen 2.772 N/A LEU 134.A N GLU 130.A O no hydrogen 2.912 N/A ILE 135.A N LYS 131.A O no hydrogen 2.931 N/A SER 136.A N ILE 132.A O no hydrogen 3.152 N/A SER 136.A OG ILE 132.A O no hydrogen 2.797 N/A SER 136.A OG HIS 133.A O no hydrogen 3.377 N/A THR 137.A N HIS 133.A O no hydrogen 3.205 N/A THR 137.A OG1 HIS 133.A O no hydrogen 3.035 N/A GLN 138.A N ILE 135.A O no hydrogen 3.238 N/A TYR 143.A OH ASP 51.A OD2 no hydrogen 2.664 N/A TYR 143.A OH GLN 138.A OE1 no hydrogen 2.777 N/A ALA 144.A N ILE 286.A O no hydrogen 2.959 N/A LEU 145.A N TYR 161.A O no hydrogen 2.792 N/A ARG 146.A N LYS 284.A O no hydrogen 2.822 N/A ARG 146.A NE ASP 160.A OD1 no hydrogen 2.614 N/A ARG 146.A NH2 ASP 160.A OD1 no hydrogen 3.295 N/A ARG 146.A NH2 ASP 160.A OD2 no hydrogen 3.127 N/A VAL 147.A N ALA 159.A O no hydrogen 2.982 N/A GLU 148.A N THR 282.A O no hydrogen 2.813 N/A LEU 149.A N SER 157.A O no hydrogen 2.914 N/A GLU 150.A N LYS 280.A O no hydrogen 3.164 N/A ASP 151.A N ARG 155.A O no hydrogen 3.128 N/A TRP 152.A N TYR 276.A OH no hydrogen 2.942 N/A TRP 152.A NE1 SER 277.A O no hydrogen 2.962 N/A ASN 153.A N ASP 151.A OD1 no hydrogen 2.807 N/A ARG 155.A N ASP 151.A OD1 no hydrogen 3.000 N/A SER 157.A N LEU 149.A O no hydrogen 3.074 N/A THR 158.A N ASP 184.A OD1 no hydrogen 3.496 N/A ALA 159.A N VAL 147.A O no hydrogen 2.939 N/A ASP 160.A N GLY 182.A O no hydrogen 3.024 N/A TYR 161.A N LEU 145.A O no hydrogen 2.900 N/A TYR 161.A OH ASP 187.A OD1 no hydrogen 2.927 N/A ALA 162.A N TYR 179.A O no hydrogen 3.047 N/A PHE 164.A N TYR 143.A O no hydrogen 3.028 N/A LYS 165.A N THR 176.A O no hydrogen 2.967 N/A VAL 166.A N SER 136.A OG no hydrogen 3.067 N/A GLY 167.A N ARG 174.A O no hydrogen 2.883 N/A ASP 171.A N PRO 168.A O no hydrogen 2.871 N/A LYS 172.A N GLU 169.A O no hydrogen 2.954 N/A LYS 172.A NZ ASN 218.A OD1 no hydrogen 3.497 N/A TYR 173.A N PRO 168.A O no hydrogen 3.051 N/A TYR 173.A OH GLU 130.A OE1 no hydrogen 2.666 N/A ARG 174.A N ASP 171.A O no hydrogen 3.136 N/A ARG 174.A NE ASP 171.A OD2 no hydrogen 2.844 N/A ARG 174.A NH1 ASP 171.A OD1 no hydrogen 2.711 N/A ARG 174.A NH1 ASP 171.A OD2 no hydrogen 3.316 N/A ARG 174.A NH2 GLY 208.A O no hydrogen 3.076 N/A LEU 175.A N MET 209.A O no hydrogen 2.882 N/A THR 176.A N LYS 165.A O no hydrogen 3.183 N/A THR 176.A OG1 LYS 165.A O no hydrogen 3.359 N/A TYR 177.A N ASN 207.A OD1 no hydrogen 3.123 N/A TYR 177.A OH PHE 189.A O no hydrogen 3.311 N/A ALA 178.A N ALA 162.A O no hydrogen 2.753 N/A ALA 181.A N ASP 160.A O no hydrogen 2.874 N/A ALA 185.A N THR 158.A O no hydrogen 3.023 N/A GLY 186.A N GLY 183.A O no hydrogen 3.216 N/A ASP 190.A N ASP 187.A O no hydrogen 3.314 N/A GLY 191.A N ALA 188.A O no hydrogen 2.920 N/A PHE 192.A N THR 204.A OG1 no hydrogen 2.969 N/A GLY 195.A N ASP 193.A OD2 no hydrogen 3.010 N/A SER 199.A N ASP 197.A OD2 no hydrogen 2.708 N/A SER 199.A OG ASP 197.A OD1 no hydrogen 3.181 N/A SER 199.A OG ASP 197.A OD2 no hydrogen 3.129 N/A ASP 200.A N ASP 197.A O no hydrogen 3.012 N/A LYS 201.A NZ ASP 190.A OD2 no hydrogen 2.708 N/A PHE 203.A N SER 199.A O no hydrogen 2.991 N/A THR 204.A N LYS 201.A O no hydrogen 3.489 N/A THR 204.A OG1 PHE 192.A O no hydrogen 3.502 N/A THR 204.A OG1 ASP 200.A O no hydrogen 2.935 N/A THR 204.A OG1 LYS 201.A O no hydrogen 3.523 N/A SER 205.A OG PHE 202.A O no hydrogen 3.215 N/A HIS 206.A N PHE 189.A O no hydrogen 2.932 N/A ASN 207.A ND2 TYR 177.A O no hydrogen 3.354 N/A GLY 208.A N LEU 175.A O no hydrogen 2.542 N/A MET 209.A N HIS 206.A O no hydrogen 2.920 N/A GLN 210.A NE2 ASP 171.A O no hydrogen 3.467 N/A GLN 210.A NE2 ASP 171.A OD1 no hydrogen 2.984 N/A PHE 211.A N LYS 172.A O no hydrogen 2.901 N/A SER 212.A N TRP 233.A O no hydrogen 2.760 N/A THR 213.A N ASN 216.A O no hydrogen 3.168 N/A THR 213.A OG1 ASP 215.A OD1 no hydrogen 2.653 N/A ASN 216.A N THR 213.A O no hydrogen 2.815 N/A ASN 216.A ND2 ASN 218.A OD1 no hydrogen 2.760 N/A ASN 218.A N SER 212.A OG no hydrogen 2.944 N/A ASP 219.A N ASP 217.A OD1 no hydrogen 3.216 N/A PHE 221.A N ASP 219.A OD2 no hydrogen 3.180 N/A CYS 225.A N ASP 219.A OD1 no hydrogen 2.897 N/A CYS 225.A SG ASP 219.A OD1 no hydrogen 3.252 N/A GLN 228.A N ASN 224.A O no hydrogen 2.989 N/A ASP 229.A N CYS 225.A O no hydrogen 2.875 N/A SER 231.A N ALA 226.A O no hydrogen 3.014 N/A SER 231.A OG HIS 242.A NE2 no hydrogen 2.523 N/A GLY 232.A N TYR 110.A OH no hydrogen 3.166 N/A TRP 233.A N SER 212.A O no hydrogen 3.073 N/A TRP 234.A NE1 TYR 173.A O no hydrogen 2.912 N/A ASN 236.A N CYS 238.A O no hydrogen 2.660 N/A ASN 236.A ND2 PHE 202.A O no hydrogen 3.019 N/A HIS 239.A NE2 ASP 229.A OD2 no hydrogen 2.656 N/A HIS 242.A N ILE 267.A O no hydrogen 2.917 N/A HIS 242.A ND1 GLY 265.A O no hydrogen 3.137 N/A HIS 242.A NE2 SER 231.A OG no hydrogen 2.523 N/A ASN 244.A ND2 GLY 232.A O no hydrogen 2.963 N/A GLY 245.A N HIS 242.A O no hydrogen 3.451 N/A VAL 246.A N ASN 264.A O no hydrogen 2.714 N/A TYR 247.A OH LYS 279.A O no hydrogen 2.613 N/A TYR 248.A OH ASN 264.A OD1 no hydrogen 2.668 N/A GLY 251.A N TYR 248.A O no hydrogen 3.176 N/A THR 252.A N GLY 250.A O no hydrogen 2.770 N/A TYR 253.A N TRP 275.A O no hydrogen 3.263 N/A TYR 253.A OH ARG 274.A O no hydrogen 2.820 N/A SER 254.A N SER 257.A OG no hydrogen 3.332 N/A ALA 256.A N SER 254.A OG no hydrogen 3.248 N/A SER 257.A N SER 254.A O no hydrogen 3.313 N/A SER 257.A OG SER 254.A O no hydrogen 2.805 N/A THR 258.A OG1 LYS 255.A O no hydrogen 2.903 N/A GLY 265.A N TYR 253.A OH no hydrogen 3.112 N/A ILE 266.A N SER 277.A OG no hydrogen 3.008 N/A TRP 268.A NE1 GLY 186.A O no hydrogen 2.945 N/A ALA 269.A N ALA 240.A O no hydrogen 2.833 N/A THR 270.A OG1 ALA 185.A O no hydrogen 2.664 N/A TRP 271.A N TRP 268.A O no hydrogen 2.903 N/A LYS 272.A N TRP 268.A O no hydrogen 3.051 N/A LYS 272.A NZ ASP 151.A OD2 no hydrogen 3.450 N/A ARG 274.A NH1 ASP 263.A OD1 no hydrogen 3.172 N/A TRP 275.A N THR 273.A OG1 no hydrogen 3.355 N/A TYR 276.A N THR 273.A O no hydrogen 2.960 N/A SER 277.A N GLY 251.A O no hydrogen 2.782 N/A SER 277.A OG VAL 246.A O no hydrogen 3.349 N/A MET 278.A N ILE 266.A O no hydrogen 3.014 N/A LYS 279.A N GLU 150.A O no hydrogen 2.817 N/A LYS 280.A N GLU 150.A O no hydrogen 3.137 N/A LYS 280.A NZ GLU 150.A OE2 no hydrogen 3.559 N/A THR 281.A N ARG 96.A O no hydrogen 2.726 N/A THR 281.A OG1 LYS 280.A O no hydrogen 3.138 N/A THR 282.A N GLU 148.A O no hydrogen 2.882 N/A MET 283.A N GLN 94.A O no hydrogen 3.101 N/A LYS 284.A N ARG 146.A O no hydrogen 3.169 N/A LYS 284.A NZ GLU 82.A OE1 no hydrogen 3.239 N/A LYS 284.A NZ GLU 148.A OE1 no hydrogen 3.421 N/A ILE 285.A N THR 91.A O no hydrogen 2.873 N/A ILE 286.A N ALA 144.A O no hydrogen 3.211 N/A PHE 288.A N PRO 142.A O no hydrogen 2.876 N/A ARG 290.A N PRO 287.A O no hydrogen 2.901 N/A ARG 290.A NE ASN 88.A OD1 no hydrogen 2.779 N/A LEU 291.A N PHE 288.A O no hydrogen 2.984 N/A