Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2zk3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 6.A OG ASN 3.A O no hydrogen 2.877 N/A ALA 7.A N ASN 3.A O no hydrogen 3.460 N/A ALA 7.A N PRO 4.A O no hydrogen 2.833 N/A ASP 8.A N GLU 5.A O no hydrogen 3.189 N/A LEU 9.A N SER 6.A O no hydrogen 2.994 N/A ARG 10.A N ALA 7.A O no hydrogen 3.252 N/A ARG 10.A NH1 GLN 218.A OE1 no hydrogen 2.491 N/A LEU 12.A N ASP 8.A O no hydrogen 3.244 N/A ALA 13.A N LEU 9.A O no hydrogen 3.173 N/A LYS 14.A N ARG 10.A O no hydrogen 2.981 N/A HIS 15.A N ALA 11.A O no hydrogen 2.737 N/A HIS 15.A NE2 SER 100.A O no hydrogen 3.081 N/A LEU 16.A N LEU 12.A O no hydrogen 3.068 N/A TYR 17.A N ALA 13.A O no hydrogen 2.974 N/A ASP 18.A N LYS 14.A O no hydrogen 3.074 N/A SER 19.A N HIS 15.A O no hydrogen 3.230 N/A SER 19.A N LEU 16.A O no hydrogen 3.085 N/A SER 19.A OG HIS 15.A O no hydrogen 3.076 N/A SER 19.A OG SER 100.A OG no hydrogen 3.086 N/A TYR 20.A N LEU 16.A O no hydrogen 2.917 N/A TYR 20.A OH ASP 179.A OD1 no hydrogen 2.715 N/A ILE 21.A N TYR 17.A O no hydrogen 3.182 N/A LYS 22.A N ASP 18.A O no hydrogen 3.344 N/A LYS 22.A NZ ASP 18.A OD2 no hydrogen 3.103 N/A SER 23.A N TYR 20.A O no hydrogen 3.027 N/A SER 23.A OG SER 19.A O no hydrogen 2.691 N/A PHE 24.A N TYR 20.A O no hydrogen 2.903 N/A LYS 28.A N ASP 179.A OD1 no hydrogen 2.694 N/A LYS 28.A NZ LEU 177.A O no hydrogen 2.356 N/A ALA 29.A N ASP 179.A OD2 no hydrogen 2.940 N/A LYS 30.A N THR 27.A OG1 no hydrogen 3.186 N/A ALA 31.A N THR 27.A O no hydrogen 3.197 N/A ARG 32.A N LYS 28.A O no hydrogen 2.830 N/A ALA 33.A N ALA 29.A O no hydrogen 3.147 N/A ILE 34.A N LYS 30.A O no hydrogen 3.055 N/A LEU 35.A N ALA 31.A O no hydrogen 2.953 N/A THR 36.A N ARG 32.A O no hydrogen 2.668 N/A THR 36.A OG1 ARG 32.A O no hydrogen 2.635 N/A THR 36.A OG1 ALA 33.A O no hydrogen 3.485 N/A THR 39.A N GLY 37.A O no hydrogen 2.333 N/A PHE 45.A N GLN 143.A O no hydrogen 2.965 N/A ILE 47.A N PHE 145.A O no hydrogen 2.780 N/A TYR 48.A N SER 52.A OG no hydrogen 3.321 N/A ASN 51.A N ASN 51.A OD1 no hydrogen 2.521 N/A SER 52.A N ASP 49.A OD1 no hydrogen 2.747 N/A SER 52.A OG ASP 49.A O no hydrogen 3.150 N/A SER 52.A OG ASP 49.A OD1 no hydrogen 2.600 N/A LEU 53.A N ASP 49.A O no hydrogen 2.571 N/A MET 54.A N MET 50.A O no hydrogen 2.459 N/A MET 55.A N ASN 51.A O no hydrogen 3.078 N/A GLY 56.A N LEU 53.A O no hydrogen 2.925 N/A GLU 57.A N MET 54.A O no hydrogen 3.251 N/A ILE 60.A N GLY 56.A O no hydrogen 3.015 N/A LYS 63.A N SER 140.A OG no hydrogen 3.191 N/A LYS 63.A NZ GLU 89.A OE2 no hydrogen 3.491 N/A THR 66.A OG1 ARG 78.A O no hydrogen 3.453 N/A ARG 78.A N GLU 74.A O no hydrogen 2.515 N/A ILE 79.A N VAL 75.A O no hydrogen 2.584 N/A PHE 80.A N ALA 76.A O no hydrogen 2.832 N/A GLN 81.A N ILE 77.A O no hydrogen 2.831 N/A GLY 82.A N ARG 78.A O no hydrogen 3.249 N/A CYS 83.A N ILE 79.A O no hydrogen 2.932 N/A GLN 84.A N PHE 80.A O no hydrogen 2.866 N/A GLN 84.A NE2 SER 262.A O no hydrogen 2.959 N/A PHE 85.A N GLN 81.A O no hydrogen 2.862 N/A ARG 86.A N GLY 82.A O no hydrogen 2.908 N/A ARG 86.A NE LYS 63.A O no hydrogen 2.780 N/A ARG 86.A NH1 ARG 86.A O no hydrogen 3.468 N/A ARG 86.A NH2 LYS 63.A O no hydrogen 2.687 N/A SER 87.A N CYS 83.A O no hydrogen 3.188 N/A SER 87.A OG CYS 83.A O no hydrogen 2.714 N/A VAL 88.A N GLN 84.A O no hydrogen 3.234 N/A GLU 89.A N PHE 85.A O no hydrogen 3.248 N/A ALA 90.A N ARG 86.A O no hydrogen 3.192 N/A VAL 91.A N SER 87.A O no hydrogen 3.064 N/A GLN 92.A N VAL 88.A O no hydrogen 2.997 N/A GLU 93.A N GLU 89.A O no hydrogen 2.838 N/A ILE 94.A N ALA 90.A O no hydrogen 2.672 N/A THR 95.A N VAL 91.A O no hydrogen 2.919 N/A THR 95.A OG1 VAL 91.A O no hydrogen 2.548 N/A GLU 96.A N GLN 92.A O no hydrogen 3.120 N/A TYR 97.A N GLU 93.A O no hydrogen 2.796 N/A TYR 97.A OH ALA 183.A O no hydrogen 2.444 N/A ALA 98.A N ILE 94.A O no hydrogen 2.826 N/A LYS 99.A N THR 95.A O no hydrogen 3.332 N/A SER 100.A N TYR 97.A O no hydrogen 2.869 N/A SER 100.A OG TYR 97.A O no hydrogen 2.628 N/A ILE 101.A N ALA 98.A O no hydrogen 2.586 N/A PHE 104.A N ILE 101.A O no hydrogen 2.831 N/A ASN 106.A N GLY 103.A O no hydrogen 2.799 N/A ASN 110.A N ASP 108.A OD1 no hydrogen 2.686 N/A GLN 112.A N ASP 108.A O no hydrogen 3.227 N/A GLN 112.A NE2 LEU 107.A O no hydrogen 2.964 N/A VAL 113.A N LEU 109.A O no hydrogen 3.343 N/A THR 114.A N ASN 110.A O no hydrogen 3.219 N/A LEU 115.A N ASP 111.A O no hydrogen 2.867 N/A LEU 116.A N GLN 112.A O no hydrogen 3.173 N/A LYS 117.A N VAL 113.A O no hydrogen 2.633 N/A LYS 117.A NZ GLU 269.A O no hydrogen 2.927 N/A LYS 117.A NZ ILE 270.A O no hydrogen 2.574 N/A LYS 117.A NZ LYS 272.A O no hydrogen 3.094 N/A TYR 118.A N THR 114.A O no hydrogen 3.213 N/A GLY 119.A N LEU 115.A O no hydrogen 2.754 N/A VAL 120.A N LEU 116.A O no hydrogen 2.898 N/A ILE 123.A N GLY 119.A O no hydrogen 2.950 N/A ILE 124.A N VAL 120.A O no hydrogen 2.857 N/A TYR 125.A N HIS 121.A O no hydrogen 3.067 N/A THR 126.A N ILE 123.A O no hydrogen 3.126 N/A THR 126.A OG1 GLU 122.A O no hydrogen 2.931 N/A MET 127.A N ILE 123.A O no hydrogen 3.032 N/A LEU 128.A N ILE 124.A O no hydrogen 2.974 N/A ALA 129.A N THR 126.A O no hydrogen 2.986 N/A SER 130.A N MET 127.A O no hydrogen 2.692 N/A SER 130.A OG MET 127.A O no hydrogen 3.135 N/A LEU 131.A N LEU 128.A O no hydrogen 3.120 N/A MET 132.A N ALA 129.A O no hydrogen 3.072 N/A ASN 133.A N GLY 136.A O no hydrogen 3.078 N/A ASP 135.A N ASN 133.A OD1 no hydrogen 2.789 N/A GLY 136.A N ASN 133.A O no hydrogen 2.954 N/A VAL 137.A N MET 146.A O no hydrogen 2.894 N/A LEU 138.A N LEU 131.A O no hydrogen 3.034 N/A ILE 139.A N GLY 144.A O no hydrogen 3.198 N/A SER 140.A OG LYS 61.A O no hydrogen 2.460 N/A SER 140.A OG GLN 143.A OE1 no hydrogen 3.234 N/A GLN 143.A N SER 140.A O no hydrogen 2.815 N/A GLY 144.A N ILE 139.A O no hydrogen 3.047 N/A PHE 145.A N PHE 45.A O no hydrogen 3.156 N/A MET 146.A N VAL 137.A O no hydrogen 2.732 N/A THR 147.A N ILE 47.A O no hydrogen 2.979 N/A THR 147.A OG1 ILE 47.A O no hydrogen 3.446 N/A ARG 148.A N ASP 135.A O no hydrogen 2.644 N/A ARG 148.A NE GLU 163.A OE2 no hydrogen 2.850 N/A ARG 148.A NH1 LYS 134.A O no hydrogen 3.377 N/A ARG 148.A NH2 GLU 163.A OE1 no hydrogen 3.229 N/A ARG 148.A NH2 GLU 163.A OE2 no hydrogen 3.334 N/A LEU 151.A N THR 147.A O no hydrogen 3.393 N/A LYS 152.A N ARG 148.A O no hydrogen 2.925 N/A SER 153.A N PHE 150.A O no hydrogen 2.984 N/A SER 153.A OG GLU 149.A O no hydrogen 3.104 N/A SER 153.A OG PHE 150.A O no hydrogen 2.364 N/A LEU 154.A N PHE 150.A O no hydrogen 3.242 N/A ARG 155.A NH2 GLU 258.A OE1 no hydrogen 2.446 N/A ASP 160.A N PRO 157.A O no hydrogen 2.573 N/A LYS 165.A NZ PHE 161.A O no hydrogen 3.100 N/A LYS 165.A NZ HIS 247.A ND1 no hydrogen 2.858 N/A PHE 166.A N MET 162.A O no hydrogen 2.936 N/A GLU 167.A N GLU 163.A O no hydrogen 2.785 N/A PHE 168.A N PRO 164.A O no hydrogen 3.159 N/A ALA 169.A N LYS 165.A O no hydrogen 2.883 N/A VAL 170.A N PHE 166.A O no hydrogen 3.149 N/A LYS 171.A NZ ASP 239.A OD2 no hydrogen 3.190 N/A PHE 172.A N PHE 168.A O no hydrogen 2.608 N/A ASN 173.A N ALA 169.A O no hydrogen 2.516 N/A ASN 173.A ND2 ALA 129.A O no hydrogen 3.073 N/A ALA 174.A N LYS 171.A O no hydrogen 3.304 N/A LEU 175.A N PHE 172.A O no hydrogen 2.860 N/A GLU 176.A N ASN 173.A O no hydrogen 2.803 N/A ASP 178.A N ASP 181.A OD2 no hydrogen 2.986 N/A SER 180.A OG ASP 178.A OD1 no hydrogen 2.585 N/A ASP 181.A N ASP 178.A O no hydrogen 2.575 N/A LEU 182.A N ASP 178.A O no hydrogen 3.203 N/A ALA 183.A N ASP 179.A O no hydrogen 2.970 N/A ILE 184.A N ASP 181.A O no hydrogen 2.936 N/A PHE 185.A N ASP 181.A O no hydrogen 3.061 N/A ILE 186.A N LEU 182.A O no hydrogen 2.697 N/A ALA 187.A N ALA 183.A O no hydrogen 3.298 N/A VAL 188.A N ILE 184.A O no hydrogen 3.154 N/A ILE 189.A N PHE 185.A O no hydrogen 3.165 N/A LEU 191.A N ALA 187.A O no hydrogen 3.130 N/A SER 192.A N ILE 190.A O no hydrogen 2.718 N/A SER 192.A OG ILE 189.A O no hydrogen 2.782 N/A ARG 195.A NH1 GLU 122.A OE1 no hydrogen 3.446 N/A ARG 195.A NH1 GLU 122.A OE2 no hydrogen 3.030 N/A ARG 195.A NH2 GLU 122.A OE1 no hydrogen 3.060 N/A LEU 198.A N ARG 195.A O no hydrogen 3.217 N/A LEU 199.A N ASP 111.A OD2 no hydrogen 2.603 N/A ASN 200.A N ASP 111.A OD1 no hydrogen 2.915 N/A LYS 202.A NZ ASP 206.A OD2 no hydrogen 2.952 N/A GLU 205.A N VAL 201.A O no hydrogen 3.293 N/A GLU 205.A N LYS 202.A O no hydrogen 2.970 N/A ASP 206.A N LYS 202.A O no hydrogen 3.254 N/A ILE 207.A N PRO 203.A O no hydrogen 3.227 N/A GLN 208.A N ILE 204.A O no hydrogen 3.118 N/A ASP 209.A N GLU 205.A O no hydrogen 2.702 N/A ASN 210.A N ASP 206.A O no hydrogen 3.368 N/A ASN 210.A N ILE 207.A O no hydrogen 2.945 N/A LEU 211.A N ILE 207.A O no hydrogen 3.043 N/A LEU 212.A N GLN 208.A O no hydrogen 2.679 N/A GLN 213.A N ASP 209.A O no hydrogen 3.164 N/A ALA 214.A N ASN 210.A O no hydrogen 2.823 N/A LEU 215.A N LEU 211.A O no hydrogen 2.667 N/A GLU 216.A N LEU 212.A O no hydrogen 2.887 N/A LEU 217.A N GLN 213.A O no hydrogen 3.216 N/A GLN 218.A N ALA 214.A O no hydrogen 2.851 N/A GLN 218.A NE2 ASP 181.A OD1 no hydrogen 3.332 N/A LEU 219.A N LEU 215.A O no hydrogen 2.971 N/A LYS 220.A N GLU 216.A O no hydrogen 3.123 N/A LEU 221.A N LEU 217.A O no hydrogen 2.789 N/A ASN 222.A N GLN 218.A O no hydrogen 2.702 N/A ASN 222.A ND2 ASP 178.A OD2 no hydrogen 2.931 N/A ASN 222.A ND2 ASP 181.A OD1 no hydrogen 3.528 N/A ASN 222.A ND2 ASP 181.A OD2 no hydrogen 3.445 N/A HIS 223.A N LYS 220.A O no hydrogen 3.411 N/A SER 226.A N HIS 223.A O no hydrogen 2.875 N/A LYS 232.A N GLN 228.A O no hydrogen 3.000 N/A LEU 233.A N LEU 229.A O no hydrogen 2.913 N/A LEU 234.A N PHE 230.A O no hydrogen 2.975 N/A GLN 235.A N ALA 231.A O no hydrogen 2.896 N/A LYS 236.A N LYS 232.A O no hydrogen 3.200 N/A MET 237.A N LEU 234.A O no hydrogen 2.902 N/A THR 238.A N GLN 235.A O no hydrogen 3.058 N/A THR 238.A OG1 GLN 235.A O no hydrogen 3.198 N/A THR 238.A OG1 ASP 239.A OD1 no hydrogen 3.542 N/A LEU 240.A N LYS 236.A O no hydrogen 3.343 N/A ARG 241.A N MET 237.A O no hydrogen 3.354 N/A ARG 241.A NE GLU 122.A OE2 no hydrogen 2.917 N/A ARG 241.A NH2 ASP 194.A OD2 no hydrogen 3.293 N/A GLN 242.A N THR 238.A O no hydrogen 3.090 N/A ILE 243.A N ASP 239.A O no hydrogen 2.998 N/A VAL 244.A N LEU 240.A O no hydrogen 2.938 N/A THR 245.A N ARG 241.A O no hydrogen 2.872 N/A THR 245.A OG1 ARG 241.A O no hydrogen 3.487 N/A GLU 246.A N GLN 242.A O no hydrogen 2.795 N/A HIS 247.A N ILE 243.A O no hydrogen 2.973 N/A HIS 247.A N VAL 244.A O no hydrogen 3.028 N/A VAL 248.A N VAL 244.A O no hydrogen 2.931 N/A GLN 249.A N THR 245.A O no hydrogen 2.832 N/A LEU 250.A N GLU 246.A O no hydrogen 3.340 N/A LEU 251.A N HIS 247.A O no hydrogen 2.634 N/A GLN 252.A N VAL 248.A O no hydrogen 2.972 N/A VAL 253.A N GLN 249.A O no hydrogen 3.309 N/A ILE 254.A N LEU 250.A O no hydrogen 3.203 N/A LYS 255.A N LEU 251.A O no hydrogen 2.971 N/A LYS 256.A N VAL 253.A O no hydrogen 3.164 N/A LYS 256.A NZ GLN 252.A O no hydrogen 2.866 N/A THR 257.A N VAL 253.A O no hydrogen 3.294 N/A THR 257.A OG1 GLU 258.A OE1 no hydrogen 3.076 N/A GLU 258.A N ILE 254.A O no hydrogen 3.057 N/A ASP 260.A N ASP 260.A OD1 no hydrogen 2.361 N/A MET 261.A N GLU 258.A O no hydrogen 3.326 N/A GLN 268.A N HIS 264.A O no hydrogen 2.897 N/A GLN 268.A N PRO 265.A O no hydrogen 2.601 N/A GLU 269.A N PRO 265.A O no hydrogen 3.151 N/A ILE 270.A N LEU 266.A O no hydrogen 3.272 N/A TYR 271.A OH HIS 121.A NE2 no hydrogen 2.508 N/A LYS 272.A N GLN 268.A O no hydrogen 2.860 N/A LYS 272.A NZ ASP 273.A OD2 no hydrogen 3.553 N/A LEU 274.A N TYR 271.A O no hydrogen 2.539 N/A