Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3anz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N ASP 4.A OD2 no hydrogen 3.063 N/A ASP 4.A N ALA 1.A O no hydrogen 2.908 N/A ILE 5.A N ASP 2.A O no hydrogen 3.026 N/A ASN 6.A N SER 3.A O no hydrogen 3.258 N/A ILE 7.A N ASP 2.A O no hydrogen 2.940 N/A THR 11.A N LYS 8.A O no hydrogen 3.168 N/A THR 11.A OG1 LYS 8.A O no hydrogen 2.696 N/A THR 12.A N ASP 2.A OD2 no hydrogen 3.432 N/A THR 12.A OG1 ASP 2.A OD2 no hydrogen 3.218 N/A ASP 13.A N GLY 10.A O no hydrogen 3.210 N/A GLY 15.A N ASP 45.A OD1 no hydrogen 3.082 N/A THR 18.A OG1 SER 16.A O no hydrogen 3.181 N/A LYS 21.A N PHE 42.A O no hydrogen 3.394 N/A GLY 23.A N TYR 40.A O no hydrogen 3.027 N/A LEU 25.A N VAL 38.A O no hydrogen 2.907 N/A THR 27.A N LYS 36.A O no hydrogen 2.924 N/A ASP 29.A N MET 34.A O no hydrogen 2.930 N/A ASN 32.A N ASP 29.A OD2 no hydrogen 3.066 N/A ASN 32.A ND2 ASP 29.A OD1 no hydrogen 2.892 N/A GLY 33.A N LYS 30.A O no hydrogen 3.286 N/A MET 34.A N ASP 29.A O no hydrogen 3.119 N/A HIS 35.A N THR 60.A O no hydrogen 2.891 N/A LYS 36.A N THR 27.A O no hydrogen 2.860 N/A LYS 36.A NZ SER 278.A OG no hydrogen 2.820 N/A LYS 36.A NZ GLU 280.A OE1 no hydrogen 2.971 N/A LYS 37.A NZ ASP 24.A OD1 no hydrogen 3.011 N/A VAL 38.A N LEU 25.A O no hydrogen 2.878 N/A PHE 39.A N ARG 56.A O no hydrogen 2.902 N/A TYR 40.A N GLY 23.A O no hydrogen 2.937 N/A SER 41.A N VAL 54.A O no hydrogen 2.889 N/A PHE 42.A N LYS 21.A O no hydrogen 2.783 N/A ILE 43.A N LEU 52.A O no hydrogen 2.856 N/A LYS 46.A NZ ASP 44.A OD1 no hydrogen 3.281 N/A ASN 47.A N ASP 45.A OD2 no hydrogen 2.923 N/A HIS 48.A N ASP 45.A O no hydrogen 2.832 N/A LYS 51.A N MET 234.A O no hydrogen 2.992 N/A LYS 51.A NZ GLN 241.A OE1 no hydrogen 3.384 N/A LYS 51.A NZ TRP 286.A O no hydrogen 3.272 N/A LEU 52.A N ILE 43.A O no hydrogen 2.996 N/A LEU 53.A N ILE 232.A O no hydrogen 2.825 N/A VAL 54.A N SER 41.A O no hydrogen 2.847 N/A ILE 55.A N THR 230.A O no hydrogen 2.812 N/A ARG 56.A N PHE 39.A O no hydrogen 2.777 N/A THR 57.A N PHE 228.A O no hydrogen 2.919 N/A THR 57.A OG1 PHE 228.A O no hydrogen 3.500 N/A LYS 58.A N LYS 37.A O no hydrogen 2.830 N/A THR 60.A N HIS 35.A O no hydrogen 2.800 N/A THR 60.A OG1 SER 225.A OG no hydrogen 2.780 N/A ILE 61.A N PHE 224.A O no hydrogen 2.829 N/A ALA 62.A N GLY 33.A O no hydrogen 3.075 N/A GLY 63.A N SER 221.A O no hydrogen 2.959 N/A GLN 64.A N SER 221.A O no hydrogen 3.163 N/A TYR 65.A OH LEU 211.A O no hydrogen 2.720 N/A ARG 66.A N ALA 79.A O no hydrogen 2.967 N/A TYR 68.A N GLY 77.A O no hydrogen 3.106 N/A TYR 68.A OH ASP 255.A OD2 no hydrogen 2.553 N/A GLU 71.A N LYS 75.A O no hydrogen 3.098 N/A LYS 75.A NZ GLN 257.A OE1 no hydrogen 2.873 N/A SER 76.A N LEU 258.A O no hydrogen 3.215 N/A SER 76.A OG SER 69.A O no hydrogen 2.824 N/A GLY 77.A N SER 69.A O no hydrogen 2.909 N/A LEU 78.A N TYR 256.A O no hydrogen 2.694 N/A ALA 79.A N ARG 66.A O no hydrogen 2.794 N/A TRP 80.A N ASP 254.A O no hydrogen 3.164 N/A TRP 80.A NE1 ASN 269.A OD1 no hydrogen 2.974 N/A SER 82.A N VAL 252.A O no hydrogen 2.825 N/A SER 82.A OG VAL 252.A O no hydrogen 3.341 N/A SER 82.A OG ASP 254.A OD2 no hydrogen 2.768 N/A ALA 83.A N VAL 252.A O no hydrogen 3.310 N/A PHE 84.A N VAL 169.A O no hydrogen 2.940 N/A LYS 85.A N GLU 250.A O no hydrogen 2.875 N/A VAL 86.A N TRP 167.A O no hydrogen 3.118 N/A GLN 87.A N ILE 248.A O no hydrogen 2.920 N/A LEU 88.A N VAL 165.A O no hydrogen 2.854 N/A GLN 89.A N ASP 246.A O no hydrogen 2.846 N/A LEU 90.A N LYS 163.A O no hydrogen 2.763 N/A GLU 94.A N PRO 91.A O no hydrogen 3.496 N/A GLN 97.A N THR 233.A O no hydrogen 3.030 N/A GLN 97.A NE2 ASP 162.A OD2 no hydrogen 3.251 N/A ILE 98.A N ASP 162.A O no hydrogen 2.857 N/A SER 99.A N VAL 231.A O no hydrogen 2.795 N/A ASP 100.A N VAL 231.A O no hydrogen 3.421 N/A TYR 101.A N ASP 100.A OD2 no hydrogen 2.870 N/A TYR 102.A N ALA 229.A O no hydrogen 2.950 N/A ARG 104.A NH1 ASP 100.A OD1 no hydrogen 3.416 N/A ARG 104.A NH1 ASP 100.A OD2 no hydrogen 3.100 N/A ASN 105.A ND2 LEU 157.A O no hydrogen 3.059 N/A THR 109.A N ASP 108.A OD1 no hydrogen 2.981 N/A GLU 111.A N LYS 147.A O no hydrogen 2.809 N/A TYR 112.A OH HIS 144.A ND1 no hydrogen 3.307 N/A MET 113.A N THR 145.A O no hydrogen 2.975 N/A THR 115.A N GLY 143.A O no hydrogen 2.925 N/A THR 117.A N SER 141.A O no hydrogen 2.891 N/A GLY 119.A N ASN 139.A O no hydrogen 2.954 N/A ASN 121.A N GLY 137.A O no hydrogen 2.923 N/A ASN 123.A N LEU 135.A O no hydrogen 2.922 N/A THR 125.A N GLY 133.A O no hydrogen 2.931 N/A ASP 127.A N LYS 131.A O no hydrogen 3.290 N/A THR 129.A OG1 ASP 127.A OD1 no hydrogen 3.028 N/A THR 129.A OG1 ASP 127.A OD2 no hydrogen 3.304 N/A LYS 131.A N ASP 127.A OD1 no hydrogen 3.238 N/A GLY 133.A N THR 125.A O no hydrogen 2.979 N/A LEU 135.A N ASN 123.A O no hydrogen 3.176 N/A GLY 137.A N ASN 121.A O no hydrogen 2.814 N/A ASN 139.A N GLY 119.A O no hydrogen 3.000 N/A SER 141.A N THR 117.A O no hydrogen 2.794 N/A GLY 143.A N THR 115.A O no hydrogen 2.876 N/A THR 145.A N MET 113.A O no hydrogen 2.863 N/A LYS 147.A N GLU 111.A O no hydrogen 2.939 N/A LYS 154.A N ILE 170.A O no hydrogen 2.895 N/A ILE 156.A N LYS 168.A O no hydrogen 2.895 N/A LEU 157.A N ASN 105.A OD1 no hydrogen 2.859 N/A GLU 158.A N GLY 166.A O no hydrogen 2.898 N/A THR 161.A N LYS 164.A O no hydrogen 2.842 N/A LYS 163.A N THR 161.A OG1 no hydrogen 2.926 N/A LYS 163.A NZ ASP 92.A O no hydrogen 3.046 N/A LYS 163.A NZ GLU 94.A O no hydrogen 2.943 N/A LYS 164.A N THR 161.A OG1 no hydrogen 2.893 N/A VAL 165.A N LEU 88.A O no hydrogen 3.098 N/A TRP 167.A N VAL 86.A O no hydrogen 2.837 N/A TRP 167.A NE1 PRO 103.A O no hydrogen 2.897 N/A LYS 168.A N ILE 156.A O no hydrogen 2.876 N/A VAL 169.A N PHE 84.A O no hydrogen 2.820 N/A ILE 170.A N LYS 154.A O no hydrogen 2.929 N/A PHE 171.A N SER 82.A O no hydrogen 2.907 N/A ASN 172.A N ASP 152.A O no hydrogen 2.781 N/A ASN 172.A ND2 PRO 151.A O no hydrogen 2.973 N/A ASN 173.A ND2 GLN 150.A OE1 no hydrogen 3.097 N/A MET 174.A N TYR 182.A O no hydrogen 2.940 N/A ASN 176.A N TRP 179.A O no hydrogen 2.985 N/A ASN 176.A ND2 GLN 194.A O no hydrogen 2.900 N/A ASN 176.A ND2 LEU 195.A O no hydrogen 3.015 N/A ASN 176.A ND2 MET 197.A O no hydrogen 3.057 N/A GLN 177.A NE2 ASN 176.A OD1 no hydrogen 3.095 N/A GLN 177.A NE2 LYS 198.A O no hydrogen 2.952 N/A TRP 179.A N ASN 176.A O no hydrogen 2.940 N/A TYR 182.A N MET 174.A O no hydrogen 2.840 N/A ASP 183.A N SER 186.A OG no hydrogen 2.996 N/A ARG 184.A NE ASP 254.A OD1 no hydrogen 2.845 N/A ARG 184.A NH1 ASP 254.A OD1 no hydrogen 3.136 N/A ARG 184.A NH1 ASP 254.A OD2 no hydrogen 3.069 N/A ARG 184.A NH1 ASP 272.A OD1 no hydrogen 2.816 N/A ASP 185.A N ASP 183.A OD1 no hydrogen 2.861 N/A SER 186.A N ASP 183.A O no hydrogen 3.258 N/A SER 186.A OG ASP 183.A OD1 no hydrogen 3.292 N/A ASN 188.A N GLY 192.A O no hydrogen 3.023 N/A VAL 190.A N ASN 188.A OD1 no hydrogen 2.839 N/A TYR 191.A N ASN 188.A OD1 no hydrogen 3.065 N/A GLY 192.A N ASN 188.A O no hydrogen 2.857 N/A ASN 193.A N GLY 267.A O no hydrogen 2.701 N/A ASN 193.A ND2 ASP 183.A O no hydrogen 3.062 N/A LEU 195.A N ASN 193.A OD1 no hydrogen 2.945 N/A MET 197.A N GLN 194.A O no hydrogen 2.989 N/A LYS 198.A N ASN 209.A O no hydrogen 2.853 N/A LYS 198.A NZ GLU 208.A O no hydrogen 3.128 N/A THR 199.A N ASN 209.A OD1 no hydrogen 2.960 N/A THR 199.A OG1 ASN 209.A OD1 no hydrogen 2.872 N/A ARG 200.A NE GLN 194.A OE1 no hydrogen 2.843 N/A ARG 200.A NH1 GLN 194.A OE1 no hydrogen 2.952 N/A GLY 202.A N THR 199.A OG1 no hydrogen 2.984 N/A LYS 205.A NZ GLU 208.A OE2 no hydrogen 2.718 N/A ALA 206.A N ALA 73.A O no hydrogen 2.935 N/A GLU 208.A N LYS 205.A O no hydrogen 2.898 N/A ASN 209.A N ALA 206.A O no hydrogen 2.826 N/A ASN 209.A ND2 THR 199.A O no hydrogen 3.058 N/A LEU 211.A N PHE 196.A O no hydrogen 2.780 N/A ASN 214.A N ASP 212.A OD1 no hydrogen 3.112 N/A LYS 215.A N ASP 212.A O no hydrogen 2.813 N/A ALA 216.A N PRO 213.A O no hydrogen 2.994 N/A LEU 219.A N SER 217.A OG no hydrogen 3.314 N/A LEU 220.A N SER 217.A O no hydrogen 2.957 N/A GLY 223.A N SER 218.A O no hydrogen 3.178 N/A PHE 224.A N ILE 61.A O no hydrogen 2.967 N/A SER 225.A OG GLY 59.A O no hydrogen 3.375 N/A SER 225.A OG THR 60.A OG1 no hydrogen 2.780 N/A PHE 228.A N THR 57.A O no hydrogen 3.281 N/A ALA 229.A N TYR 102.A O no hydrogen 2.816 N/A THR 230.A N ILE 55.A O no hydrogen 2.847 N/A VAL 231.A N ASP 100.A O no hydrogen 2.842 N/A ILE 232.A N LEU 53.A O no hydrogen 2.823 N/A THR 233.A N GLN 97.A O no hydrogen 2.860 N/A MET 234.A N LYS 51.A O no hydrogen 2.978 N/A ARG 236.A NE ASP 44.A OD2 no hydrogen 3.122 N/A ARG 236.A NH1 ASP 44.A OD2 no hydrogen 2.835 N/A ARG 236.A NH1 HIS 48.A O no hydrogen 3.225 N/A ARG 236.A NH2 HIS 48.A O no hydrogen 2.933 N/A LYS 237.A N ASP 235.A OD1 no hydrogen 2.912 N/A ALA 238.A N ASP 235.A O no hydrogen 3.222 N/A LYS 240.A NZ GLN 242.A O no hydrogen 3.311 N/A GLN 241.A NE2 ASP 235.A O no hydrogen 3.149 N/A GLN 241.A NE2 ALA 238.A O no hydrogen 3.001 N/A GLN 242.A NE2 ASP 285.A OD1 no hydrogen 3.460 N/A GLN 242.A NE2 GLU 287.A OE1 no hydrogen 3.108 N/A THR 243.A N ILE 284.A O no hydrogen 2.927 N/A ILE 245.A N TYR 282.A O no hydrogen 2.936 N/A ASP 246.A N GLN 89.A O no hydrogen 2.945 N/A VAL 247.A N GLU 280.A O no hydrogen 2.972 N/A ILE 248.A N GLN 87.A O no hydrogen 2.816 N/A TYR 249.A N SER 278.A O no hydrogen 2.892 N/A TYR 249.A OH LYS 58.A O no hydrogen 2.493 N/A GLU 250.A N LYS 85.A O no hydrogen 2.890 N/A ARG 251.A N ASP 276.A O no hydrogen 2.895 N/A ARG 251.A NE ALA 62.A O no hydrogen 2.848 N/A ARG 251.A NH1 ASN 32.A O no hydrogen 2.822 N/A ARG 251.A NH1 ALA 62.A O no hydrogen 2.837 N/A ARG 251.A NH2 ASN 32.A O no hydrogen 3.040 N/A ARG 251.A NH2 ASP 276.A OD2 no hydrogen 2.853 N/A VAL 252.A N ALA 83.A O no hydrogen 2.948 N/A ARG 253.A N TRP 274.A O no hydrogen 2.936 N/A ARG 253.A NH1 ASP 276.A OD1 no hydrogen 3.098 N/A ASP 254.A N TRP 80.A O no hydrogen 2.776 N/A ASP 255.A N THR 270.A O no hydrogen 3.008 N/A TYR 256.A N LEU 78.A O no hydrogen 2.805 N/A TYR 256.A OH ASN 193.A O no hydrogen 2.764 N/A GLN 257.A N THR 268.A O no hydrogen 2.852 N/A LEU 258.A N SER 76.A O no hydrogen 3.031 N/A HIS 259.A N LYS 266.A O no hydrogen 2.840 N/A TRP 260.A N ASN 74.A O no hydrogen 2.792 N/A THR 261.A N ASN 264.A O no hydrogen 2.888 N/A THR 261.A OG1 THR 263.A OG1 no hydrogen 3.316 N/A THR 261.A OG1 ASN 264.A O no hydrogen 3.129 N/A THR 263.A N THR 261.A OG1 no hydrogen 3.033 N/A THR 263.A OG1 THR 261.A OG1 no hydrogen 3.316 N/A THR 263.A OG1 ASN 264.A OD1 no hydrogen 2.924 N/A ASN 264.A N THR 261.A OG1 no hydrogen 3.121 N/A ASN 264.A ND2 VAL 190.A O no hydrogen 3.485 N/A ASN 264.A ND2 TRP 265.A O no hydrogen 3.049 N/A TRP 265.A N ARG 200.A O no hydrogen 2.955 N/A TRP 265.A NE1 GLY 202.A O no hydrogen 3.069 N/A LYS 266.A N HIS 259.A O no hydrogen 2.960 N/A GLY 267.A N TYR 191.A O no hydrogen 2.935 N/A THR 268.A N GLN 257.A O no hydrogen 2.926 N/A ASN 269.A ND2 ASP 254.A OD1 no hydrogen 3.050 N/A THR 270.A N ASP 255.A O no hydrogen 2.908 N/A LYS 271.A NZ ASP 185.A OD1 no hydrogen 2.885 N/A LYS 271.A NZ ASP 185.A OD2 no hydrogen 3.266 N/A ASP 272.A N ASP 254.A OD2 no hydrogen 2.836 N/A TRP 274.A N ARG 253.A O no hydrogen 3.209 N/A ASP 276.A N ARG 251.A O no hydrogen 2.836 N/A ARG 277.A NE GLU 250.A OE1 no hydrogen 3.109 N/A SER 278.A N TYR 249.A O no hydrogen 2.882 N/A SER 278.A OG ASP 29.A OD1 no hydrogen 2.578 N/A GLU 280.A N VAL 247.A O no hydrogen 3.000 N/A ARG 281.A N GLU 295.A OE2 no hydrogen 2.980 N/A ARG 281.A NE ASP 246.A OD1 no hydrogen 2.903 N/A ARG 281.A NH1 ASP 246.A OD2 no hydrogen 3.079 N/A TYR 282.A N ILE 245.A O no hydrogen 2.828 N/A LYS 283.A N THR 292.A O no hydrogen 2.787 N/A ILE 284.A N THR 243.A O no hydrogen 2.716 N/A ASP 285.A N GLU 290.A O no hydrogen 2.890 N/A TRP 286.A N GLN 241.A O no hydrogen 3.039 N/A TRP 286.A NE1 THR 243.A OG1 no hydrogen 3.021 N/A GLU 287.A N ASP 285.A OD1 no hydrogen 3.085 N/A LYS 288.A N ASP 285.A OD1 no hydrogen 3.218 N/A LYS 288.A NZ GLU 290.A OE2 no hydrogen 3.202 N/A GLU 290.A N ASP 285.A O no hydrogen 3.196 N/A MET 291.A N TYR 40.A OH no hydrogen 3.449 N/A THR 292.A N LYS 283.A O no hydrogen 3.039 N/A ASN 293.A ND2 GLU 280.A OE2 no hydrogen 3.167 N/A LEU 294.A N ARG 281.A O no hydrogen 3.009 N/A