Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3brf_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 7.A N THR 3.A O no hydrogen 3.510 N/A ASP 9.A N ASP 5.A O no hydrogen 3.312 N/A PHE 10.A N ARG 6.A O no hydrogen 3.228 N/A LEU 11.A N MET 7.A O no hydrogen 2.780 N/A SER 12.A N ILE 8.A O no hydrogen 3.069 N/A SER 12.A OG ILE 8.A O no hydrogen 2.527 N/A ASN 13.A N ASP 9.A O no hydrogen 3.249 N/A ASN 13.A ND2 ASP 9.A O no hydrogen 2.988 N/A ASN 13.A ND2 ASP 9.A OD1 no hydrogen 3.339 N/A TYR 17.A N LYS 14.A O no hydrogen 3.150 N/A GLU 18.A N LYS 14.A O no hydrogen 3.019 N/A CYS 19.A N PHE 311.A O no hydrogen 2.836 N/A VAL 20.A N ILE 49.A O no hydrogen 3.041 N/A ILE 21.A N TYR 309.A O no hydrogen 2.832 N/A SER 22.A N TYR 47.A O no hydrogen 2.963 N/A ILE 23.A N ALA 307.A O no hydrogen 2.899 N/A PHE 24.A N CYS 45.A O no hydrogen 2.799 N/A HIS 25.A N ASP 305.A O no hydrogen 3.098 N/A LYS 27.A N SER 303.A O no hydrogen 2.957 N/A ALA 29.A N LYS 134.A O no hydrogen 2.945 N/A LYS 31.A N ILE 136.A O no hydrogen 2.761 N/A SER 32.A N ILE 102.A O no hydrogen 2.855 N/A SER 32.A OG ILE 102.A O no hydrogen 3.495 N/A TYR 33.A N GLU 36.A OE1 no hydrogen 2.749 N/A GLY 34.A N ASP 104.A OD1 no hydrogen 3.209 N/A GLU 36.A N TYR 33.A O no hydrogen 3.174 N/A ARG 38.A N SER 32.A OG no hydrogen 2.927 N/A ARG 38.A NE GLU 36.A OE1 no hydrogen 3.262 N/A ARG 38.A NH1 GLU 36.A OE2 no hydrogen 3.489 N/A PHE 40.A N LEU 100.A O no hydrogen 2.848 N/A CYS 45.A N PHE 24.A O no hydrogen 2.870 N/A CYS 45.A SG PHE 24.A O no hydrogen 4.033 N/A ILE 46.A N CYS 95.A O no hydrogen 2.942 N/A TYR 47.A N SER 22.A O no hydrogen 2.786 N/A LEU 48.A N ASP 93.A O no hydrogen 2.918 N/A ILE 49.A N VAL 20.A O no hydrogen 2.926 N/A GLY 50.A N ASN 90.A O no hydrogen 3.058 N/A TRP 53.A NE1 VAL 20.A O no hydrogen 2.969 N/A LYS 54.A N GLN 51.A O no hydrogen 2.766 N/A LEU 55.A N GLN 51.A O no hydrogen 3.406 N/A LYS 56.A N GLY 52.A O no hydrogen 2.797 N/A LYS 56.A NZ GLU 313.A OE1 no hydrogen 2.850 N/A LYS 57.A N TRP 53.A O no hydrogen 3.073 N/A LYS 57.A NZ THR 68.A O no hydrogen 3.144 N/A ASP 58.A N LYS 54.A O no hydrogen 2.961 N/A ARG 59.A N LEU 55.A O no hydrogen 2.968 N/A ARG 59.A NH1 GLU 313.A O no hydrogen 2.782 N/A ARG 59.A NH1 GLU 313.A OE2 no hydrogen 3.312 N/A ARG 59.A NH2 GLU 313.A O no hydrogen 3.119 N/A VAL 60.A N LYS 56.A O no hydrogen 3.098 N/A ALA 61.A N LYS 57.A O no hydrogen 2.913 N/A GLN 62.A N ASP 58.A O no hydrogen 3.077 N/A LEU 63.A N ARG 59.A O no hydrogen 2.876 N/A TYR 64.A N VAL 60.A O no hydrogen 2.937 N/A LYS 65.A N GLN 62.A O no hydrogen 3.255 N/A THR 66.A OG1 GLN 62.A O no hydrogen 3.226 N/A THR 68.A OG1 GLU 69.A OE1 no hydrogen 2.962 N/A THR 68.A OG1 GLU 69.A OE2 no hydrogen 3.059 N/A VAL 71.A N PHE 118.A O no hydrogen 2.765 N/A TYR 73.A N GLN 116.A O no hydrogen 2.991 N/A ILE 74.A N GLN 84.A O no hydrogen 2.783 N/A GLY 75.A N ASN 114.A O no hydrogen 3.097 N/A SER 81.A N SER 78.A O no hydrogen 3.347 N/A GLN 84.A N ILE 74.A O no hydrogen 2.859 N/A GLN 84.A NE2 THR 99.A O no hydrogen 3.037 N/A GLN 85.A N GLN 85.A OE1 no hydrogen 2.599 N/A LEU 86.A N ALA 72.A O no hydrogen 2.738 N/A TYR 92.A N LEU 48.A O no hydrogen 2.590 N/A ASP 93.A N LEU 48.A O no hydrogen 3.322 N/A TYR 94.A N ASP 93.A OD1 no hydrogen 2.870 N/A TYR 94.A OH THR 186.A O no hydrogen 2.640 N/A CYS 95.A N ILE 46.A O no hydrogen 3.273 N/A ALA 97.A N PRO 44.A O no hydrogen 2.882 N/A THR 99.A OG1 GLN 84.A OE1 no hydrogen 2.620 N/A SER 103.A OG SER 105.A OG no hydrogen 2.737 N/A SER 105.A N SER 103.A OG no hydrogen 3.018 N/A SER 105.A OG SER 103.A OG no hydrogen 2.737 N/A ASP 106.A N SER 103.A O no hydrogen 3.162 N/A LYS 107.A NZ ASP 104.A O no hydrogen 2.942 N/A ARG 108.A N ASP 106.A OD1 no hydrogen 3.161 N/A ARG 108.A NE ASP 106.A OD1 no hydrogen 2.908 N/A ARG 108.A NH1 ILE 76.A O no hydrogen 2.926 N/A ARG 108.A NH2 ILE 76.A O no hydrogen 2.938 N/A ARG 108.A NH2 ASP 106.A OD2 no hydrogen 2.814 N/A PHE 111.A N ILE 133.A O no hydrogen 3.066 N/A LEU 113.A N SER 130.A OG no hydrogen 2.791 N/A ASN 114.A N GLY 75.A O no hydrogen 3.101 N/A ASN 114.A ND2 PHE 128.A O no hydrogen 3.412 N/A ALA 115.A N PHE 128.A O no hydrogen 2.793 N/A GLN 116.A N TYR 73.A O no hydrogen 2.875 N/A PHE 117.A N GLY 126.A O no hydrogen 2.908 N/A PHE 118.A N VAL 71.A O no hydrogen 2.866 N/A TYR 119.A N MET 123.A O no hydrogen 3.180 N/A GLY 122.A N TYR 119.A O no hydrogen 2.783 N/A ILE 125.A N PHE 117.A O no hydrogen 2.929 N/A GLY 126.A N PHE 117.A O no hydrogen 3.345 N/A GLY 127.A N SER 323.A OG no hydrogen 2.958 N/A PHE 128.A N ALA 115.A O no hydrogen 2.750 N/A SER 130.A N LEU 113.A O no hydrogen 2.876 N/A SER 130.A OG LEU 113.A O no hydrogen 3.545 N/A SER 130.A OG GLN 131.A O no hydrogen 3.051 N/A ILE 133.A N PHE 111.A O no hydrogen 2.922 N/A LYS 134.A N LYS 27.A O no hydrogen 2.818 N/A VAL 135.A N LYS 109.A O no hydrogen 2.900 N/A ILE 136.A N ALA 29.A O no hydrogen 2.801 N/A LYS 142.A N SER 140.A OG no hydrogen 3.274 N/A LYS 142.A NZ SER 140.A OG no hydrogen 3.273 N/A LYS 142.A NZ LYS 142.A O no hydrogen 2.907 N/A LYS 143.A NZ LYS 141.A O no hydrogen 3.523 N/A LYS 143.A NZ GLU 251.A OE2 no hydrogen 3.537 N/A SER 145.A OG ASP 146.A OD2 no hydrogen 3.202 N/A TYR 149.A OH LYS 27.A O no hydrogen 3.416 N/A CYS 151.A N LYS 148.A O no hydrogen 3.001 N/A SER 154.A N GLY 210.A O no hydrogen 2.794 N/A SER 154.A OG ARG 208.A O no hydrogen 2.897 N/A GLY 155.A N ILE 193.A O no hydrogen 2.638 N/A THR 156.A N ALA 153.A O no hydrogen 3.212 N/A THR 156.A OG1 ALA 153.A O no hydrogen 2.653 N/A VAL 158.A N PHE 191.A O no hydrogen 2.710 N/A ALA 159.A N ILE 302.A O no hydrogen 2.942 N/A PHE 161.A N THR 300.A O no hydrogen 2.964 N/A ASN 162.A N ARG 172.A O no hydrogen 2.916 N/A ARG 163.A NH1 THR 171.A OG1 no hydrogen 3.188 N/A GLN 167.A N LEU 164.A O no hydrogen 2.649 N/A SER 170.A N THR 168.A OG1 no hydrogen 3.299 N/A ARG 172.A N ASN 162.A O no hydrogen 2.978 N/A ARG 172.A NH1 ALA 183.A O no hydrogen 2.773 N/A TYR 173.A N SER 184.A O no hydrogen 2.805 N/A LEU 174.A N LEU 160.A O no hydrogen 2.840 N/A HIS 175.A N HIS 182.A O no hydrogen 3.091 N/A GLU 177.A N ALA 180.A O no hydrogen 2.910 N/A HIS 182.A N HIS 175.A O no hydrogen 2.693 N/A HIS 182.A ND1 HIS 175.A O no hydrogen 2.919 N/A ALA 183.A N ASP 276.A O no hydrogen 2.716 N/A SER 184.A N TYR 173.A O no hydrogen 2.808 N/A SER 184.A OG LYS 187.A O no hydrogen 3.157 N/A THR 186.A N SER 184.A OG no hydrogen 2.873 N/A LYS 187.A N SER 184.A OG no hydrogen 2.740 N/A TRP 188.A NE1 PRO 43.A O no hydrogen 2.753 N/A GLY 189.A N LEU 174.A O no hydrogen 2.735 N/A PHE 191.A N VAL 158.A O no hydrogen 2.807 N/A THR 192.A N VAL 221.A O no hydrogen 2.734 N/A ILE 193.A N THR 156.A O no hydrogen 2.935 N/A HIS 194.A N LYS 219.A O no hydrogen 2.733 N/A LEU 195.A N SER 154.A OG no hydrogen 2.984 N/A PHE 196.A N VAL 217.A O no hydrogen 3.044 N/A ASP 197.A N ALA 206.A O no hydrogen 2.773 N/A ARG 208.A N LEU 195.A O no hydrogen 2.901 N/A ARG 208.A NH1 PHE 196.A O no hydrogen 2.921 N/A VAL 212.A N ILE 152.A O no hydrogen 2.777 N/A TYR 214.A N GLU 251.A O no hydrogen 2.985 N/A TYR 214.A OH HIS 257.A ND1 no hydrogen 2.556 N/A GLY 215.A N ILE 234.A O no hydrogen 2.702 N/A SER 216.A N TYR 213.A O no hydrogen 3.155 N/A SER 216.A OG TYR 213.A O no hydrogen 2.803 N/A VAL 218.A N LEU 232.A O no hydrogen 2.624 N/A LYS 219.A N HIS 194.A O no hydrogen 2.680 N/A LYS 219.A NZ LEU 229.A O no hydrogen 3.432 N/A VAL 221.A N THR 192.A O no hydrogen 2.968 N/A ASP 222.A N ILE 227.A O no hydrogen 2.922 N/A SER 223.A N ALA 190.A O no hydrogen 3.455 N/A SER 223.A OG ALA 190.A O no hydrogen 2.516 N/A THR 225.A N ASP 222.A OD1 no hydrogen 2.818 N/A THR 225.A OG1 ASP 222.A OD1 no hydrogen 2.633 N/A GLY 226.A N ASP 222.A O no hydrogen 3.305 N/A ILE 227.A N THR 225.A OG1 no hydrogen 3.372 N/A LEU 229.A N LEU 220.A O no hydrogen 3.075 N/A LEU 232.A N VAL 218.A O no hydrogen 2.916 N/A ARG 233.A N GLN 262.A O no hydrogen 3.003 N/A ARG 233.A NH1 GLN 262.A OE1 no hydrogen 3.275 N/A ILE 234.A N SER 216.A O no hydrogen 3.186 N/A ARG 235.A N ALA 260.A O no hydrogen 2.844 N/A ARG 235.A NE GLN 262.A OE1 no hydrogen 2.840 N/A ARG 235.A NH2 GLN 262.A OE1 no hydrogen 2.592 N/A ARG 235.A NH2 GLU 267.A OE2 no hydrogen 3.494 N/A VAL 237.A N LYS 258.A O no hydrogen 3.127 N/A ASP 238.A N GLN 241.A O no hydrogen 2.942 N/A LYS 239.A NZ ASP 238.A OD1 no hydrogen 3.477 N/A VAL 242.A N HIS 291.A O no hydrogen 2.807 N/A ILE 243.A N LYS 236.A O no hydrogen 2.995 N/A CYS 248.A N ASP 245.A O no hydrogen 2.843 N/A SER 249.A N ALA 246.A O no hydrogen 3.025 N/A SER 249.A OG ALA 246.A O no hydrogen 3.150 N/A GLU 250.A N SER 247.A O no hydrogen 2.919 N/A GLU 251.A N CYS 248.A O no hydrogen 2.696 N/A VAL 253.A N VAL 212.A O no hydrogen 2.851 N/A SER 254.A N HIS 257.A ND1 no hydrogen 3.222 N/A SER 254.A OG LEU 150.A O no hydrogen 3.168 N/A GLN 255.A N LEU 150.A O no hydrogen 3.060 N/A GLN 255.A NE2 LEU 150.A O no hydrogen 3.076 N/A GLN 255.A NE2 SER 303.A OG no hydrogen 2.722 N/A LEU 256.A N ILE 301.A O no hydrogen 2.698 N/A HIS 257.A N SER 254.A O no hydrogen 3.196 N/A HIS 257.A NE2 SER 140.A O no hydrogen 2.933 N/A LYS 258.A NZ THR 300.A OG1 no hydrogen 3.020 N/A CYS 259.A N TRP 299.A O no hydrogen 2.939 N/A ALA 260.A N ARG 235.A O no hydrogen 2.750 N/A GLN 262.A N ARG 233.A O no hydrogen 2.953 N/A GLN 262.A NE2 TYR 270.A OH no hydrogen 3.052 N/A MET 263.A N VAL 269.A O no hydrogen 2.722 N/A VAL 269.A N ASN 266.A O no hydrogen 2.960 N/A TYR 270.A N HIS 281.A O no hydrogen 2.589 N/A LEU 271.A N PHE 261.A O no hydrogen 2.899 N/A CYS 272.A N ILE 279.A O no hydrogen 2.962 N/A CYS 272.A SG LEU 273.A O no hydrogen 3.621 N/A LEU 273.A N GLY 296.A O no hydrogen 3.022 N/A SER 274.A N LYS 277.A O no hydrogen 2.849 N/A LYS 277.A N SER 274.A O no hydrogen 2.828 N/A ILE 279.A N CYS 272.A O no hydrogen 2.842 N/A HIS 281.A N TYR 270.A O no hydrogen 2.790 N/A ALA 283.A N LEU 268.A O no hydrogen 2.591 N/A THR 284.A N GLN 292.A O no hydrogen 3.258 N/A ILE 286.A N ARG 290.A O no hydrogen 3.033 N/A ASN 287.A N ARG 290.A O no hydrogen 3.229 N/A ARG 290.A N ASN 287.A O no hydrogen 3.362 N/A ARG 290.A NE HIS 289.A O no hydrogen 3.148 N/A HIS 291.A N VAL 242.A O no hydrogen 3.082 N/A GLN 292.A N THR 284.A O no hydrogen 2.820 N/A ILE 293.A N GLN 240.A O no hydrogen 2.940 N/A ASN 294.A N HIS 281.A NE2 no hydrogen 3.211 N/A ALA 297.A N ASN 294.A O no hydrogen 3.052 N/A ALA 298.A N ASP 295.A O no hydrogen 3.270 N/A TRP 299.A N CYS 259.A O no hydrogen 2.851 N/A TRP 299.A NE1 LEU 271.A O no hydrogen 3.294 N/A THR 300.A N PHE 161.A O no hydrogen 2.733 N/A ILE 301.A N HIS 257.A O no hydrogen 3.226 N/A ILE 302.A N ALA 159.A O no hydrogen 3.326 N/A SER 303.A N GLN 255.A OE1 no hydrogen 2.678 N/A THR 304.A N LYS 157.A O no hydrogen 3.163 N/A ASP 305.A N HIS 25.A O no hydrogen 2.728 N/A LYS 306.A N ASP 305.A OD1 no hydrogen 2.662 N/A LYS 306.A NZ GLU 308.A OE1 no hydrogen 2.538 N/A ALA 307.A N ILE 23.A O no hydrogen 2.802 N/A TYR 309.A N ILE 21.A O no hydrogen 2.787 N/A TYR 309.A OH VAL 129.A O no hydrogen 2.470 N/A PHE 311.A N CYS 19.A O no hydrogen 3.036 N/A PHE 312.A N VAL 412.A O no hydrogen 2.884 N/A ALA 314.A N GLY 410.A O no hydrogen 2.750 N/A ILE 322.A N ILE 125.A O no hydrogen 2.984 N/A VAL 327.A N ARG 347.A O no hydrogen 3.040 N/A GLY 329.A N HIS 345.A O no hydrogen 2.426 N/A GLU 332.A N GLU 343.A O no hydrogen 3.212 N/A ASP 334.A N ARG 341.A O no hydrogen 3.367 N/A GLU 338.A N GLU 338.A OE1 no hydrogen 2.776 N/A SER 340.A OG GLY 337.A O no hydrogen 3.103 N/A VAL 342.A N CYS 374.A O no hydrogen 2.786 N/A GLU 343.A N GLU 332.A O no hydrogen 2.984 N/A LEU 344.A N LEU 372.A O no hydrogen 2.937 N/A GLY 346.A N GLU 370.A O no hydrogen 3.344 N/A ARG 347.A N VAL 327.A O no hydrogen 2.948 N/A ARG 347.A NH2 TYR 309.A OH no hydrogen 3.009 N/A PHE 349.A N GLU 369.A O no hydrogen 2.877 N/A LYS 354.A N VAL 406.A O no hydrogen 3.103 N/A TRP 356.A N SER 404.A O no hydrogen 2.718 N/A THR 360.A OG1 GLN 381.A O no hydrogen 3.553 N/A THR 364.A OG1 VAL 362.A O no hydrogen 2.974 N/A THR 365.A N HIS 373.A O no hydrogen 3.387 N/A THR 365.A OG1 HIS 373.A O no hydrogen 2.627 N/A SER 368.A N SER 371.A O no hydrogen 3.322 N/A SER 368.A OG SER 371.A OG no hydrogen 3.234 N/A SER 371.A OG SER 368.A OG no hydrogen 3.234 N/A LEU 372.A N LEU 344.A O no hydrogen 3.015 N/A CYS 374.A N VAL 342.A O no hydrogen 2.977 N/A CYS 374.A SG VAL 342.A O no hydrogen 3.630 N/A CYS 374.A SG SER 375.A O no hydrogen 3.220 N/A SER 375.A N GLU 363.A O no hydrogen 3.046 N/A GLN 381.A N PRO 378.A O no hydrogen 2.859 N/A ASN 384.A N THR 387.A O no hydrogen 2.550 N/A GLU 385.A N ASN 384.A OD1 no hydrogen 2.659 N/A GLN 386.A N ASN 384.A OD1 no hydrogen 2.916 N/A THR 387.A N ASN 384.A OD1 no hydrogen 2.907 N/A THR 387.A OG1 VAL 382.A O no hydrogen 3.285 N/A THR 387.A OG1 ASN 384.A OD1 no hydrogen 3.164 N/A PHE 391.A N HIS 388.A O no hydrogen 3.195 N/A THR 392.A N HIS 388.A O no hydrogen 2.885 N/A THR 392.A OG1 HIS 388.A O no hydrogen 3.366 N/A ASN 393.A N ASP 398.A O no hydrogen 3.116 N/A ASN 393.A ND2 THR 396.A OG1 no hydrogen 2.784 N/A ASP 398.A N THR 396.A OG1 no hydrogen 3.294 N/A GLU 400.A N PHE 391.A O no hydrogen 2.989 N/A VAL 401.A N PHE 419.A O no hydrogen 2.745 N/A ILE 403.A N LEU 417.A O no hydrogen 2.918 N/A SER 404.A N TRP 356.A O no hydrogen 2.999 N/A LEU 405.A N TYR 413.A O no hydrogen 3.157 N/A VAL 406.A N LYS 354.A O no hydrogen 3.174 N/A ARG 407.A N VAL 411.A O no hydrogen 2.811 N/A ARG 407.A NH1 PRO 321.A O no hydrogen 2.911 N/A ARG 407.A NH2 PRO 321.A O no hydrogen 3.426 N/A ARG 407.A NH2 ASP 409.A OD2 no hydrogen 2.595 N/A GLY 410.A N ARG 407.A O no hydrogen 2.858 N/A VAL 412.A N PHE 312.A O no hydrogen 2.801 N/A TYR 413.A N LEU 405.A O no hydrogen 2.647 N/A TYR 413.A OH ILE 322.A O no hydrogen 2.889 N/A SER 414.A OG GLU 18.A OE2 no hydrogen 2.345 N/A SER 415.A N ILE 403.A O no hydrogen 3.477 N/A SER 415.A OG ILE 403.A O no hydrogen 2.795 N/A LEU 417.A N SER 415.A OG no hydrogen 3.095 N/A PHE 419.A N VAL 401.A O no hydrogen 2.521 N/A TYR 421.A N VAL 399.A O no hydrogen 2.854 N/A TYR 421.A OH PRO 377.A O no hydrogen 3.333 N/A