Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3cfx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N ASP 31.A O no hydrogen 3.085 N/A THR 5.A N ASP 54.A OD2 no hydrogen 2.809 N/A VAL 6.A N GLN 33.A O no hydrogen 3.034 N/A PHE 7.A N VAL 55.A O no hydrogen 2.893 N/A HIS 8.A N GLU 35.A O no hydrogen 3.005 N/A HIS 8.A ND1 ALA 9.A O no hydrogen 2.752 N/A ALA 9.A N ALA 57.A O no hydrogen 3.036 N/A SER 11.A OG TYR 255.A OH no hydrogen 2.715 N/A LEU 12.A N ALA 9.A O no hydrogen 3.099 N/A SER 13.A N GLY 10.A O no hydrogen 3.055 N/A SER 13.A OG GLY 10.A O no hydrogen 2.854 N/A PHE 16.A N LEU 12.A O no hydrogen 2.777 N/A GLU 17.A N SER 13.A O no hydrogen 2.975 N/A GLU 17.A N VAL 14.A O no hydrogen 3.123 N/A GLU 18.A N VAL 14.A O no hydrogen 3.279 N/A LEU 19.A N PRO 15.A O no hydrogen 3.014 N/A GLU 20.A N PHE 16.A O no hydrogen 2.848 N/A ALA 21.A N GLU 17.A O no hydrogen 3.054 N/A GLU 22.A N GLU 18.A O no hydrogen 2.984 N/A PHE 23.A N LEU 19.A O no hydrogen 2.806 N/A GLU 24.A N GLU 20.A O no hydrogen 2.881 N/A ALA 25.A N ALA 21.A O no hydrogen 3.049 N/A GLN 26.A N GLU 22.A O no hydrogen 3.051 N/A GLN 26.A NE2 GLU 22.A OE1 no hydrogen 2.848 N/A HIS 27.A ND1 PHE 23.A O no hydrogen 3.008 N/A HIS 27.A NE2 GLU 271.A OE2 no hydrogen 3.172 N/A VAL 30.A N HIS 27.A O no hydrogen 3.088 N/A ASP 31.A N GLU 2.A O no hydrogen 3.131 N/A VAL 32.A N GLU 24.A OE2 no hydrogen 2.800 N/A GLN 33.A N LEU 4.A O no hydrogen 2.801 N/A GLN 33.A NE2 ASP 31.A OD2 no hydrogen 2.597 N/A ARG 34.A NE GLU 20.A OE2 no hydrogen 2.797 N/A ARG 34.A NH1 HIS 8.A NE2 no hydrogen 3.010 N/A GLU 35.A N VAL 6.A O no hydrogen 2.869 N/A ALA 37.A N HIS 8.A O no hydrogen 3.204 N/A GLN 41.A N ASP 121.A O no hydrogen 3.173 N/A GLN 41.A NE2 GLN 41.A O no hydrogen 3.082 N/A SER 42.A N GLY 38.A O no hydrogen 2.797 N/A SER 42.A OG ALA 37.A O no hydrogen 3.000 N/A SER 42.A OG GLY 38.A O no hydrogen 3.502 N/A VAL 43.A N SER 39.A O no hydrogen 2.955 N/A ARG 44.A N ALA 40.A O no hydrogen 2.955 N/A ARG 44.A NH1 ASN 120.A O no hydrogen 2.927 N/A ARG 44.A NH2 GLN 41.A OE1 no hydrogen 3.310 N/A ARG 44.A NH2 ASN 120.A O no hydrogen 2.971 N/A LYS 45.A N GLN 41.A O no hydrogen 3.015 N/A LYS 45.A NZ GLU 35.A OE1 no hydrogen 2.734 N/A ILE 46.A N VAL 43.A O no hydrogen 2.936 N/A THR 47.A N VAL 43.A O no hydrogen 2.910 N/A THR 47.A OG1 VAL 43.A O no hydrogen 3.395 N/A GLU 48.A N ARG 44.A O no hydrogen 2.782 N/A LEU 49.A N ARG 44.A O no hydrogen 2.963 N/A LYS 51.A N LYS 45.A O no hydrogen 2.909 N/A ASP 54.A N THR 5.A O no hydrogen 2.713 N/A VAL 55.A N THR 5.A O no hydrogen 3.246 N/A LEU 56.A N THR 258.A O no hydrogen 2.938 N/A ALA 57.A N PHE 7.A O no hydrogen 2.988 N/A SER 58.A N GLY 256.A O no hydrogen 2.825 N/A SER 58.A OG ASP 60.A O no hydrogen 2.796 N/A ALA 59.A N SER 39.A OG no hydrogen 2.846 N/A ASP 60.A N SER 58.A OG no hydrogen 2.937 N/A TYR 61.A N VAL 254.A O no hydrogen 2.904 N/A ALA 62.A N ASP 60.A OD1 no hydrogen 3.235 N/A LEU 63.A N ASP 60.A O no hydrogen 3.097 N/A ILE 64.A N TYR 61.A O no hydrogen 2.999 N/A SER 66.A N ALA 62.A O no hydrogen 3.103 N/A SER 66.A OG ALA 62.A O no hydrogen 3.046 N/A SER 66.A OG LEU 63.A O no hydrogen 3.422 N/A LEU 67.A N LEU 63.A O no hydrogen 2.916 N/A MET 68.A N ILE 64.A O no hydrogen 2.737 N/A VAL 69.A N ILE 64.A O no hydrogen 3.240 N/A TYR 72.A N MET 68.A O no hydrogen 2.756 N/A TYR 72.A OH GLU 71.A OE2 no hydrogen 3.236 N/A ALA 73.A N MET 68.A O no hydrogen 3.094 N/A ALA 77.A N VAL 257.A O no hydrogen 2.847 N/A PHE 79.A N TYR 255.A O no hydrogen 3.075 N/A ARG 81.A N PRO 291.A O no hydrogen 2.866 N/A ARG 81.A NE ILE 293.A OXT no hydrogen 2.919 N/A ARG 81.A NH2 ILE 293.A OXT no hydrogen 3.216 N/A ASN 82.A ND2 SER 208.A OG no hydrogen 2.789 N/A ASN 82.A ND2 TYR 255.A OH no hydrogen 3.017 N/A GLN 83.A N ASN 82.A OD1 no hydrogen 2.844 N/A MET 84.A N ASP 225.A O no hydrogen 3.101 N/A ILE 85.A N ILE 205.A O no hydrogen 2.970 N/A LEU 86.A N VAL 218.A O no hydrogen 3.289 N/A ALA 87.A N LEU 203.A O no hydrogen 2.814 N/A TYR 88.A N GLU 216.A O no hydrogen 2.956 N/A THR 89.A N SER 92.A OG no hydrogen 2.939 N/A GLU 91.A N THR 89.A OG1 no hydrogen 3.103 N/A SER 92.A N THR 89.A O no hydrogen 2.969 N/A SER 92.A OG THR 89.A O no hydrogen 3.328 N/A SER 92.A OG ASP 201.A O no hydrogen 2.695 N/A LYS 93.A N ASP 201.A OD1 no hydrogen 3.005 N/A TYR 94.A OH ASP 111.A OD2 no hydrogen 2.714 N/A GLY 95.A N SER 92.A O no hydrogen 3.170 N/A GLU 97.A N TYR 94.A O no hydrogen 2.936 N/A ILE 98.A N TYR 94.A O no hydrogen 3.051 N/A ASN 99.A N ASN 102.A OD1 no hydrogen 2.887 N/A THR 100.A OG1 ALA 219.A O no hydrogen 2.652 N/A ASP 101.A N ASN 99.A OD1 no hydrogen 2.812 N/A ASN 102.A N ASN 99.A O no hydrogen 3.184 N/A ASN 102.A N ASN 99.A OD1 no hydrogen 3.026 N/A ASN 102.A ND2 GLU 97.A O no hydrogen 3.213 N/A TRP 103.A N ASN 99.A O no hydrogen 2.996 N/A TRP 103.A NE1 TYR 139.A OH no hydrogen 2.947 N/A GLU 105.A N ASN 102.A O no hydrogen 2.833 N/A ILE 106.A N ASN 102.A O no hydrogen 3.153 N/A LEU 107.A N TRP 103.A O no hydrogen 2.990 N/A ARG 108.A N TYR 104.A O no hydrogen 3.092 N/A ARG 108.A NE ASP 147.A OD2 no hydrogen 2.869 N/A ARG 108.A NH1 GLU 105.A OE2 no hydrogen 3.108 N/A ARG 108.A NH1 ASP 141.A OD2 no hydrogen 2.929 N/A ARG 108.A NH2 ASP 141.A OD1 no hydrogen 2.944 N/A ARG 108.A NH2 ASP 141.A OD2 no hydrogen 3.416 N/A ARG 108.A NH2 ASP 147.A OD2 no hydrogen 2.962 N/A ARG 109.A N ILE 106.A O no hydrogen 3.081 N/A ARG 109.A NH1 GLU 97.A OE2 no hydrogen 2.972 N/A ARG 109.A NH2 GLU 97.A OE1 no hydrogen 2.828 N/A ARG 109.A NH2 GLU 97.A OE2 no hydrogen 3.513 N/A ASP 111.A N ASP 111.A OD1 no hydrogen 2.641 N/A VAL 112.A N ARG 109.A O no hydrogen 2.992 N/A ARG 113.A N ASP 201.A OD2 no hydrogen 3.014 N/A ARG 113.A NH2 ILE 182.A O no hydrogen 3.277 N/A TYR 114.A N LYS 181.A O no hydrogen 2.936 N/A TYR 114.A OH LEU 148.A O no hydrogen 2.674 N/A GLY 115.A N TYR 202.A O no hydrogen 2.846 N/A PHE 116.A N MET 183.A O no hydrogen 3.314 N/A SER 117.A OG ASP 122.A OD2 no hydrogen 2.726 N/A ASN 118.A N ARG 185.A O no hydrogen 2.865 N/A ASN 118.A ND2 SER 172.A OG no hydrogen 2.897 N/A ASN 120.A N ASN 118.A OD1 no hydrogen 2.767 N/A ASN 120.A ND2 PRO 170.A O no hydrogen 2.935 N/A ASN 120.A ND2 SER 172.A OG no hydrogen 3.272 N/A ASP 121.A N ASN 118.A O no hydrogen 2.890 N/A ASP 122.A N ASN 118.A O no hydrogen 2.913 N/A GLY 125.A N ASP 122.A O no hydrogen 2.803 N/A TYR 126.A N ASP 122.A O no hydrogen 3.070 N/A TYR 126.A OH ASP 60.A OD2 no hydrogen 2.646 N/A ARG 127.A N PRO 123.A O no hydrogen 2.732 N/A ARG 127.A NH1 ALA 59.A O no hydrogen 2.972 N/A ARG 127.A NH1 TYR 206.A OH no hydrogen 2.742 N/A ARG 127.A NH2 ALA 59.A O no hydrogen 2.961 N/A SER 128.A N ALA 124.A O no hydrogen 3.082 N/A SER 128.A OG GLY 125.A O no hydrogen 2.764 N/A SER 128.A OG GLN 129.A OE1 no hydrogen 3.055 N/A GLN 129.A NE2 TYR 145.A OH no hydrogen 2.650 N/A MET 130.A N TYR 126.A O no hydrogen 3.050 N/A VAL 131.A N ARG 127.A O no hydrogen 2.878 N/A THR 132.A N SER 128.A O no hydrogen 3.250 N/A THR 132.A OG1 SER 128.A O no hydrogen 2.790 N/A THR 132.A OG1 TYR 204.A OH no hydrogen 2.838 N/A GLN 133.A N GLN 129.A O no hydrogen 3.006 N/A LEU 134.A N MET 130.A O no hydrogen 2.936 N/A ALA 135.A N VAL 131.A O no hydrogen 3.012 N/A GLU 136.A N GLN 133.A O no hydrogen 3.163 N/A TYR 138.A N LEU 134.A O no hydrogen 3.447 N/A TYR 139.A N ALA 135.A O no hydrogen 2.893 N/A TYR 139.A OH THR 100.A O no hydrogen 2.741 N/A ASN 140.A N SER 137.A O no hydrogen 3.296 N/A ASP 141.A N GLU 136.A O no hydrogen 2.861 N/A MET 143.A N ASP 141.A OD1 no hydrogen 3.131 N/A TYR 145.A N GLU 136.A OE2 no hydrogen 2.806 N/A ASP 147.A N MET 143.A O no hydrogen 2.750 N/A LEU 148.A N ILE 144.A O no hydrogen 3.019 N/A MET 149.A N TYR 145.A O no hydrogen 2.909 N/A LEU 150.A N TYR 145.A O no hydrogen 3.171 N/A ALA 151.A N ASP 146.A O no hydrogen 2.889 N/A ASN 152.A N MET 149.A O no hydrogen 3.085 N/A ASN 152.A ND2 LEU 148.A O no hydrogen 3.163 N/A THR 153.A OG1 MET 149.A O no hydrogen 2.872 N/A GLY 154.A N ILE 175.A O no hydrogen 2.719 N/A MET 155.A N THR 153.A OG1 no hydrogen 3.114 N/A THR 156.A N HIS 168.A O no hydrogen 3.132 N/A THR 158.A N LEU 166.A O no hydrogen 3.032 N/A THR 158.A OG1 GLU 160.A OE1 no hydrogen 3.565 N/A GLU 160.A N THR 164.A O no hydrogen 2.713 N/A GLY 163.A N GLU 160.A O no hydrogen 2.664 N/A ALA 165.A N LYS 237.A O no hydrogen 2.987 N/A LEU 166.A N THR 158.A O no hydrogen 2.811 N/A ILE 167.A N GLN 239.A O no hydrogen 2.805 N/A HIS 168.A N THR 156.A O no hydrogen 2.760 N/A VAL 169.A N GLU 241.A O no hydrogen 2.888 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.563 N/A GLU 174.A N ALA 171.A O no hydrogen 2.695 N/A ILE 175.A N SER 172.A O no hydrogen 3.209 N/A ASN 178.A N ASN 152.A O no hydrogen 2.840 N/A ASN 178.A ND2 ASN 152.A OD1 no hydrogen 3.159 N/A SER 180.A N ASN 178.A OD1 no hydrogen 2.984 N/A SER 180.A OG ASN 178.A OD1 no hydrogen 2.969 N/A LYS 181.A N ASN 178.A O no hydrogen 2.924 N/A LYS 181.A NZ LEU 107.A O no hydrogen 2.728 N/A LYS 181.A NZ ARG 109.A O no hydrogen 2.723 N/A LYS 181.A NZ VAL 112.A O no hydrogen 2.784 N/A ILE 182.A N ASN 178.A O no hydrogen 2.854 N/A MET 183.A N TYR 114.A O no hydrogen 3.052 N/A ARG 185.A NH1 LEU 184.A O no hydrogen 2.968 N/A SER 186.A OG ASP 121.A OD2 no hydrogen 2.948 N/A MET 187.A N GLU 190.A OE2 no hydrogen 3.171 N/A GLU 188.A N ASP 122.A OD2 no hydrogen 2.789 N/A VAL 189.A N GLU 188.A OE2 no hydrogen 2.865 N/A GLU 190.A N MET 187.A O no hydrogen 3.031 N/A LEU 191.A N GLU 188.A O no hydrogen 2.987 N/A SER 192.A N VAL 189.A O no hydrogen 3.347 N/A SER 192.A OG VAL 189.A O no hydrogen 3.195 N/A LEU 195.A N LEU 191.A O no hydrogen 3.079 N/A GLU 196.A N SER 192.A O no hydrogen 2.963 N/A THR 197.A N SER 193.A O no hydrogen 2.857 N/A THR 197.A OG1 SER 193.A O no hydrogen 2.957 N/A THR 197.A OG1 ALA 194.A O no hydrogen 3.527 N/A GLY 198.A N LEU 195.A O no hydrogen 3.131 N/A ILE 200.A N ALA 194.A O no hydrogen 3.238 N/A ASP 201.A N ARG 113.A O no hydrogen 2.788 N/A TYR 202.A N ARG 113.A O no hydrogen 3.248 N/A TYR 202.A OH LYS 93.A O no hydrogen 2.663 N/A LEU 203.A N ALA 87.A O no hydrogen 2.905 N/A TYR 204.A N GLY 115.A O no hydrogen 2.970 N/A TYR 204.A OH THR 132.A OG1 no hydrogen 2.838 N/A ILE 205.A N ILE 85.A O no hydrogen 3.259 N/A ARG 207.A N GLN 83.A O no hydrogen 2.815 N/A ARG 207.A NE GLU 211.A OE2 no hydrogen 3.144 N/A ARG 207.A NH1 GLN 83.A OE1 no hydrogen 2.980 N/A SER 208.A N ASN 82.A OD1 no hydrogen 3.444 N/A ALA 210.A N TYR 206.A O no hydrogen 3.117 N/A GLU 211.A N ARG 207.A O no hydrogen 2.935 N/A GLN 212.A N SER 208.A O no hydrogen 2.979 N/A GLN 212.A NE2 ASN 288.A O no hydrogen 2.884 N/A HIS 213.A N VAL 209.A O no hydrogen 3.027 N/A GLY 214.A N GLU 211.A O no hydrogen 3.276 N/A PHE 215.A N ALA 210.A O no hydrogen 2.859 N/A GLU 216.A N TYR 88.A O no hydrogen 2.847 N/A TYR 217.A OH GLU 211.A OE2 no hydrogen 3.380 N/A VAL 218.A N LEU 86.A O no hydrogen 2.827 N/A ILE 224.A N PRO 221.A O no hydrogen 2.872 N/A ASP 225.A N PRO 221.A O no hydrogen 2.988 N/A SER 227.A N ASP 225.A OD1 no hydrogen 2.963 N/A SER 227.A OG ASP 225.A OD1 no hydrogen 2.525 N/A SER 227.A OG ASP 225.A OD2 no hydrogen 3.169 N/A SER 227.A OG SER 228.A OG no hydrogen 3.049 N/A SER 228.A N TYR 235.A OH no hydrogen 2.973 N/A SER 228.A OG SER 227.A OG no hydrogen 3.049 N/A TYR 231.A N SER 228.A O no hydrogen 3.083 N/A ALA 232.A N LEU 229.A O no hydrogen 3.149 N/A ASN 234.A ND2 ALA 223.A O no hydrogen 2.767 N/A TYR 235.A N TYR 231.A O no hydrogen 3.072 N/A TYR 235.A OH PRO 222.A O no hydrogen 2.528 N/A SER 236.A N ALA 232.A O no hydrogen 3.211 N/A SER 236.A OG ASP 233.A O no hydrogen 2.831 N/A LYS 237.A N ASN 234.A O no hydrogen 3.048 N/A VAL 238.A N TYR 235.A O no hydrogen 3.368 N/A GLN 239.A N ALA 165.A O no hydrogen 2.868 N/A GLN 239.A NE2 THR 249.A OG1 no hydrogen 2.957 N/A VAL 240.A N VAL 248.A O no hydrogen 2.890 N/A GLU 241.A N ILE 167.A O no hydrogen 2.729 N/A MET 242.A N GLU 246.A O no hydrogen 2.845 N/A VAL 243.A N ASN 120.A OD1 no hydrogen 2.879 N/A GLY 245.A N MET 242.A O no hydrogen 2.946 N/A GLU 246.A N ASN 244.A OD1 no hydrogen 2.998 N/A VAL 248.A N VAL 240.A O no hydrogen 2.888 N/A GLY 250.A N VAL 238.A O no hydrogen 2.899 N/A SER 251.A OG THR 249.A O no hydrogen 3.473 N/A ILE 253.A N LEU 226.A O no hydrogen 2.730 N/A TYR 255.A N ALA 80.A O no hydrogen 2.770 N/A TYR 255.A OH SER 11.A OG no hydrogen 2.715 N/A GLY 256.A N SER 58.A O no hydrogen 2.980 N/A VAL 257.A N ALA 77.A O no hydrogen 2.880 N/A THR 258.A N LEU 56.A O no hydrogen 2.930 N/A THR 258.A OG1 TRP 75.A O no hydrogen 2.746 N/A ASN 261.A N TYR 72.A O no hydrogen 2.889 N/A ASN 261.A ND2 GLU 71.A O no hydrogen 3.103 N/A ALA 263.A N PRO 260.A O no hydrogen 3.140 N/A GLU 264.A N ASP 54.A OD1 no hydrogen 3.064 N/A ASN 265.A N ASP 54.A OD1 no hydrogen 2.835 N/A LEU 268.A N ASN 265.A OD1 no hydrogen 3.144 N/A ALA 269.A N ASN 265.A O no hydrogen 2.969 N/A THR 270.A N SER 266.A O no hydrogen 2.892 N/A THR 270.A OG1 SER 266.A O no hydrogen 3.189 N/A GLU 271.A N GLU 267.A O no hydrogen 3.380 N/A PHE 272.A N LEU 268.A O no hydrogen 3.048 N/A VAL 273.A N ALA 269.A O no hydrogen 2.859 N/A ALA 274.A N THR 270.A O no hydrogen 2.926 N/A LEU 275.A N GLU 271.A O no hydrogen 3.037 N/A LEU 276.A N PHE 272.A O no hydrogen 2.933 N/A LEU 277.A N VAL 273.A O no hydrogen 2.927 N/A GLY 278.A N ALA 274.A O no hydrogen 2.902 N/A GLN 282.A N GLY 278.A O no hydrogen 2.915 N/A GLN 282.A NE2 LEU 277.A O no hydrogen 2.862 N/A GLN 283.A N GLU 279.A O no hydrogen 3.050 N/A ILE 284.A N THR 280.A O no hydrogen 3.170 N/A PHE 285.A N GLY 281.A O no hydrogen 3.000 N/A ILE 286.A N GLN 282.A O no hydrogen 3.064 N/A GLU 287.A N GLN 283.A O no hydrogen 2.949 N/A ASN 288.A N PHE 285.A O no hydrogen 2.997 N/A ASN 288.A ND2 GLU 18.A OE2 no hydrogen 2.846 N/A ASN 288.A ND2 ILE 284.A O no hydrogen 2.910 N/A GLY 289.A N ILE 286.A O no hydrogen 3.227 N/A GLN 290.A N PHE 285.A O no hydrogen 2.935 N/A