Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3co8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N ARG 347.A O no hydrogen 2.904 N/A ILE 4.A N GLU 2.A O no hydrogen 3.001 N/A ARG 6.A N ALA 3.A O no hydrogen 3.257 N/A ARG 6.A NH1 ASP 273.A OD1 no hydrogen 3.200 N/A ARG 6.A NH1 ASP 273.A OD2 no hydrogen 3.023 N/A ARG 6.A NH2 ASP 273.A OD1 no hydrogen 2.723 N/A THR 8.A OG1 SER 236.A OG no hydrogen 2.861 N/A THR 8.A OG1 PRO 268.A O no hydrogen 2.705 N/A ARG 9.A N LYS 235.A O no hydrogen 2.857 N/A ARG 9.A NE GLU 11.A OE2 no hydrogen 2.776 N/A ARG 9.A NH1 SER 7.A O no hydrogen 2.860 N/A ILE 10.A N LYS 349.A O no hydrogen 2.848 N/A GLU 11.A N GLU 233.A O no hydrogen 2.861 N/A SER 13.A N VAL 231.A O no hydrogen 2.687 N/A SER 13.A OG SER 16.A OG no hydrogen 3.082 N/A LYS 14.A N VAL 352.A O no hydrogen 3.234 N/A LYS 14.A NZ GLU 55.A OE1 no hydrogen 2.917 N/A LYS 14.A NZ GLU 55.A OE2 no hydrogen 2.923 N/A SER 15.A OG SER 13.A OG no hydrogen 3.164 N/A SER 16.A N SER 13.A OG no hydrogen 3.214 N/A SER 16.A OG SER 13.A OG no hydrogen 3.082 N/A SER 16.A OG PRO 230.A O no hydrogen 3.182 N/A LEU 17.A N SER 13.A O no hydrogen 3.256 N/A ALA 18.A N LYS 14.A O no hydrogen 3.033 N/A TYR 19.A N SER 15.A O no hydrogen 3.027 N/A ASN 20.A N SER 16.A O no hydrogen 3.021 N/A ASN 20.A ND2 VAL 212.A O no hydrogen 3.152 N/A ASN 20.A ND2 LYS 229.A O no hydrogen 2.885 N/A VAL 21.A N LEU 17.A O no hydrogen 3.021 N/A GLN 22.A N ALA 18.A O no hydrogen 3.112 N/A TYR 23.A N TYR 19.A O no hydrogen 2.910 N/A THR 24.A N ASN 20.A O no hydrogen 2.877 N/A THR 24.A OG1 ASN 20.A O no hydrogen 2.747 N/A LYS 25.A N VAL 21.A O no hydrogen 3.004 N/A LYS 25.A NZ LYS 31.A O no hydrogen 2.966 N/A LYS 25.A NZ ASP 59.A OD2 no hydrogen 2.893 N/A GLN 26.A N GLN 22.A O no hydrogen 2.999 N/A VAL 27.A N TYR 23.A O no hydrogen 2.995 N/A SER 28.A N THR 24.A O no hydrogen 3.044 N/A SER 28.A OG THR 24.A O no hydrogen 2.677 N/A GLY 29.A N LYS 25.A O no hydrogen 2.807 N/A ALA 30.A N SER 28.A OG no hydrogen 3.160 N/A LYS 31.A N SER 204.A O no hydrogen 3.121 N/A THR 32.A N SER 204.A O no hydrogen 3.156 N/A LEU 33.A N ASP 59.A OD2 no hydrogen 2.916 N/A TRP 34.A N ALA 206.A O no hydrogen 2.755 N/A LEU 35.A N GLY 60.A O no hydrogen 2.913 N/A ALA 36.A N VAL 208.A O no hydrogen 2.816 N/A VAL 37.A N ALA 62.A O no hydrogen 2.760 N/A SER 39.A N GLU 68.A OE2 no hydrogen 3.159 N/A ALA 41.A N VAL 37.A O no hydrogen 2.994 N/A TYR 42.A N LYS 38.A O no hydrogen 2.990 N/A GLY 43.A N SER 39.A O no hydrogen 3.102 N/A HIS 44.A N ALA 41.A O no hydrogen 2.991 N/A HIS 44.A ND1 ALA 41.A O no hydrogen 2.779 N/A GLY 45.A N ASN 40.A O no hydrogen 2.791 N/A LEU 46.A N ASN 40.A OD1 no hydrogen 2.840 N/A GLN 48.A NE2 HIS 44.A O no hydrogen 2.972 N/A VAL 49.A N GLY 45.A O no hydrogen 2.936 N/A SER 50.A N LEU 46.A O no hydrogen 3.023 N/A SER 50.A OG LEU 46.A O no hydrogen 2.770 N/A LYS 51.A N LEU 47.A O no hydrogen 3.049 N/A CYS 56.A N ILE 52.A O no hydrogen 3.149 N/A CYS 56.A N ALA 53.A O no hydrogen 3.038 N/A CYS 56.A SG LYS 14.A O no hydrogen 3.436 N/A CYS 56.A SG ILE 52.A O no hydrogen 3.318 N/A GLY 57.A N ARG 54.A O no hydrogen 3.016 N/A VAL 58.A N ALA 53.A O no hydrogen 3.039 N/A ASP 59.A N LEU 33.A O no hydrogen 2.845 N/A LEU 61.A N PHE 80.A O no hydrogen 2.769 N/A ALA 62.A N LEU 35.A O no hydrogen 2.785 N/A VAL 63.A N LEU 82.A O no hydrogen 2.865 N/A SER 64.A N GLU 68.A OE1 no hydrogen 2.869 N/A VAL 65.A N GLU 68.A OE1 no hydrogen 3.203 N/A GLU 68.A N VAL 65.A O no hydrogen 3.315 N/A ILE 70.A N LEU 66.A O no hydrogen 2.950 N/A ALA 71.A N ASP 67.A O no hydrogen 2.929 N/A ILE 72.A N GLU 68.A O no hydrogen 3.210 N/A ARG 73.A N GLY 69.A O no hydrogen 3.137 N/A ARG 73.A NE TYR 98.A O no hydrogen 2.930 N/A ARG 73.A NH1 ILE 77.A O no hydrogen 2.990 N/A ARG 73.A NH1 ASP 79.A O no hydrogen 2.782 N/A ARG 73.A NH2 ASP 79.A O no hydrogen 3.112 N/A ARG 73.A NH2 TYR 98.A O no hydrogen 3.097 N/A GLN 74.A N ILE 70.A O no hydrogen 2.899 N/A ALA 75.A N ILE 72.A O no hydrogen 3.213 N/A GLY 76.A N ARG 73.A O no hydrogen 2.963 N/A ILE 77.A N ILE 72.A O no hydrogen 3.267 N/A LEU 82.A N LEU 61.A O no hydrogen 2.929 N/A ILE 83.A N LEU 101.A O no hydrogen 2.904 N/A LEU 84.A N VAL 63.A O no hydrogen 2.786 N/A GLY 85.A N SER 64.A O no hydrogen 3.105 N/A LYS 90.A N ASP 88.A OD1 no hydrogen 3.449 N/A TYR 91.A N ASP 88.A O no hydrogen 2.965 N/A ALA 92.A N VAL 89.A O no hydrogen 3.100 N/A ALA 95.A N TYR 91.A O no hydrogen 3.123 N/A SER 96.A N ALA 92.A O no hydrogen 3.094 N/A SER 96.A OG GLU 120.A OE1 no hydrogen 3.272 N/A LYS 97.A N PRO 93.A O no hydrogen 2.980 N/A LYS 97.A NZ GLU 120.A OE2 no hydrogen 3.238 N/A TYR 98.A N ILE 94.A O no hydrogen 3.204 N/A HIS 99.A N SER 96.A O no hydrogen 3.143 N/A PHE 100.A N ALA 95.A O no hydrogen 3.011 N/A LEU 101.A N ILE 81.A O no hydrogen 2.900 N/A THR 102.A N SER 123.A O no hydrogen 2.763 N/A THR 102.A OG1 PHE 100.A O no hydrogen 3.051 N/A THR 103.A OG1 ILE 83.A O no hydrogen 2.600 N/A VAL 104.A N ASN 125.A O no hydrogen 2.867 N/A TRP 109.A N SER 106.A OG no hydrogen 3.144 N/A TRP 109.A NE1 ILE 87.A O no hydrogen 2.994 N/A LEU 110.A N SER 106.A O no hydrogen 3.475 N/A LYS 111.A N LEU 107.A O no hydrogen 2.999 N/A LYS 111.A NZ ASP 108.A OD1 no hydrogen 2.910 N/A SER 112.A N ASP 108.A O no hydrogen 3.137 N/A SER 112.A OG ASP 108.A O no hydrogen 3.065 N/A ALA 113.A N TRP 109.A O no hydrogen 2.952 N/A ASP 114.A N LEU 110.A O no hydrogen 2.971 N/A ILE 116.A N ALA 113.A O no hydrogen 3.143 N/A LYS 121.A NZ PHE 156.A O no hydrogen 3.401 N/A LEU 122.A N HIS 155.A O no hydrogen 2.842 N/A SER 123.A OG ASP 159.A OD2 no hydrogen 2.686 N/A VAL 124.A N SER 157.A O no hydrogen 2.856 N/A ASN 125.A N THR 102.A O no hydrogen 2.777 N/A ASN 125.A ND2 THR 103.A OG1 no hydrogen 2.914 N/A LEU 126.A N GLY 160.A O no hydrogen 2.852 N/A ALA 127.A N VAL 104.A O no hydrogen 3.109 N/A VAL 128.A N PHE 162.A O no hydrogen 2.812 N/A ASP 129.A N VAL 136.A O no hydrogen 2.888 N/A THR 130.A N ASN 132.A OD1 no hydrogen 3.005 N/A THR 130.A OG1 ASN 132.A OD1 no hydrogen 3.489 N/A THR 130.A OG1 THR 163.A OG1 no hydrogen 2.712 N/A THR 130.A OG1 GLN 170.A OE1 no hydrogen 3.301 N/A GLY 131.A N ASP 129.A OD1 no hydrogen 3.169 N/A ASN 132.A ND2 HIS 164.A O no hydrogen 2.844 N/A VAL 136.A N ALA 127.A O no hydrogen 3.146 N/A LYS 139.A NZ GLU 176.A O no hydrogen 3.021 N/A LYS 139.A NZ ASP 179.A O no hydrogen 3.061 N/A LYS 140.A NZ ASP 144.A OD2 no hydrogen 3.084 N/A ASP 141.A N SER 138.A OG no hydrogen 3.245 N/A LEU 142.A N SER 138.A O no hydrogen 3.171 N/A LYS 143.A N LYS 139.A O no hydrogen 2.896 N/A LYS 143.A NZ GLU 147.A OE2 no hydrogen 2.815 N/A ASP 144.A N LYS 140.A O no hydrogen 2.846 N/A GLU 145.A N ASP 141.A O no hydrogen 3.246 N/A GLU 145.A N LEU 142.A O no hydrogen 3.130 N/A ILE 146.A N LEU 142.A O no hydrogen 2.994 N/A GLU 147.A N LYS 143.A O no hydrogen 2.935 N/A PHE 148.A N ASP 144.A O no hydrogen 3.201 N/A LEU 149.A N GLU 145.A O no hydrogen 3.050 N/A GLN 150.A N ILE 146.A O no hydrogen 3.087 N/A GLU 151.A N GLU 147.A O no hydrogen 3.326 N/A HIS 152.A N LEU 149.A O no hydrogen 3.432 N/A HIS 152.A ND1 PHE 148.A O no hydrogen 2.788 N/A SER 153.A OG GLN 150.A O no hydrogen 3.447 N/A HIS 155.A N HIS 152.A O no hydrogen 3.125 N/A HIS 155.A ND1 ASP 114.A OD1 no hydrogen 2.852 N/A PHE 156.A N HIS 152.A O no hydrogen 3.245 N/A SER 157.A N LEU 122.A O no hydrogen 2.847 N/A SER 157.A OG ASP 159.A OD1 no hydrogen 2.819 N/A SER 157.A OG ASP 159.A OD2 no hydrogen 3.318 N/A TYR 158.A OH ILE 182.A O no hydrogen 2.828 N/A ASP 159.A N VAL 124.A O no hydrogen 3.113 N/A GLY 160.A N VAL 124.A O no hydrogen 2.948 N/A ILE 161.A N TYR 185.A O no hydrogen 3.019 N/A PHE 162.A N LEU 126.A O no hydrogen 3.011 N/A THR 163.A OG1 VAL 128.A O no hydrogen 2.859 N/A THR 163.A OG1 THR 130.A OG1 no hydrogen 2.712 N/A THR 163.A OG1 ASN 132.A OD1 no hydrogen 3.237 N/A GLN 168.A NE2 GLU 198.A OE2 no hydrogen 3.559 N/A LYS 171.A N PHE 167.A O no hydrogen 2.908 N/A ASN 172.A N GLN 168.A O no hydrogen 3.118 N/A ARG 173.A N ARG 169.A O no hydrogen 3.088 N/A ARG 173.A NH2 ARG 137.A O no hydrogen 2.761 N/A TRP 174.A N GLN 170.A O no hydrogen 2.912 N/A TYR 175.A N LYS 171.A O no hydrogen 3.184 N/A TYR 175.A OH PRO 200.A O no hydrogen 2.758 N/A GLU 176.A N ASN 172.A O no hydrogen 3.092 N/A LEU 177.A N ARG 173.A O no hydrogen 2.994 N/A ILE 178.A N TRP 174.A O no hydrogen 3.149 N/A LEU 181.A N ILE 178.A O no hydrogen 3.123 N/A TYR 185.A N ASP 159.A O no hydrogen 2.981 N/A HIS 187.A N ILE 161.A O no hydrogen 3.216 N/A ASN 189.A ND2 ALA 166.A O no hydrogen 2.968 N/A ALA 192.A N ASN 189.A OD1 no hydrogen 3.341 N/A ALA 193.A N ASN 189.A O no hydrogen 2.852 N/A TYR 194.A OH GLU 216.A OE1 no hydrogen 3.040 N/A TYR 194.A OH GLU 216.A OE2 no hydrogen 2.632 N/A HIS 195.A N ALA 192.A O no hydrogen 2.927 N/A HIS 195.A ND1 GLU 198.A OE1 no hydrogen 2.722 N/A HIS 195.A ND1 GLU 198.A OE2 no hydrogen 3.226 N/A SER 196.A OG SER 28.A O no hydrogen 3.367 N/A LYS 197.A NZ SER 28.A O no hydrogen 3.406 N/A LYS 197.A NZ SER 196.A OG no hydrogen 2.765 N/A GLU 198.A N HIS 195.A O no hydrogen 3.063 N/A LEU 199.A N SER 196.A O no hydrogen 3.244 N/A CYS 202.A N LEU 199.A O no hydrogen 3.170 N/A CYS 202.A SG TYR 175.A OH no hydrogen 3.307 N/A CYS 202.A SG LEU 199.A O no hydrogen 3.512 N/A ASN 203.A ND2 SER 196.A O no hydrogen 2.896 N/A ALA 206.A N THR 32.A O no hydrogen 2.923 N/A ARG 207.A NH1 THR 163.A O no hydrogen 3.548 N/A ARG 207.A NH2 THR 163.A O no hydrogen 3.291 N/A ARG 207.A NH2 HIS 164.A ND1 no hydrogen 2.918 N/A VAL 208.A N TRP 34.A O no hydrogen 2.976 N/A VAL 211.A N SER 190.A OG no hydrogen 2.989 N/A TYR 213.A N GLY 209.A O no hydrogen 3.173 N/A TYR 213.A N THR 210.A O no hydrogen 3.224 N/A TYR 213.A OH ALA 36.A O no hydrogen 2.854 N/A GLY 214.A N VAL 211.A O no hydrogen 3.014 N/A VAL 215.A N THR 210.A O no hydrogen 3.241 N/A GLU 216.A N TYR 327.A OH no hydrogen 2.867 N/A SER 218.A N GLU 216.A OE1 no hydrogen 3.043 N/A SER 218.A OG TYR 194.A OH no hydrogen 2.852 N/A SER 218.A OG GLU 216.A OE1 no hydrogen 2.846 N/A GLU 219.A N GLU 216.A O no hydrogen 2.848 N/A GLY 220.A N GLU 216.A OE1 no hydrogen 2.937 N/A VAL 221.A N SER 218.A O no hydrogen 3.406 N/A LEU 222.A N SER 218.A OG no hydrogen 2.834 N/A LYS 227.A NZ ASP 226.A OD2 no hydrogen 2.673 N/A LEU 228.A N ILE 225.A O no hydrogen 3.406 N/A LYS 229.A N ASN 20.A OD1 no hydrogen 3.045 N/A GLU 233.A N GLU 11.A O no hydrogen 3.118 N/A LEU 234.A N ILE 316.A O no hydrogen 2.819 N/A LYS 235.A N ARG 9.A O no hydrogen 2.967 N/A LYS 235.A NZ GLU 11.A OE1 no hydrogen 3.049 N/A LYS 235.A NZ GLU 233.A OE1 no hydrogen 3.457 N/A SER 236.A N VAL 313.A O no hydrogen 2.882 N/A SER 236.A OG THR 8.A OG1 no hydrogen 2.861 N/A LEU 238.A N THR 311.A O no hydrogen 3.009 N/A THR 239.A N THR 266.A O no hydrogen 2.870 N/A THR 239.A OG1 THR 266.A O no hydrogen 3.138 N/A LYS 242.A N ILE 264.A O no hydrogen 3.109 N/A LYS 243.A NZ ASP 261.A OD2 no hydrogen 3.562 N/A ILE 244.A N THR 262.A O no hydrogen 3.006 N/A GLY 247.A N THR 258.A O no hydrogen 3.019 N/A GLU 248.A N THR 258.A OG1 no hydrogen 3.066 N/A ILE 250.A N PHE 256.A O no hydrogen 2.900 N/A SER 251.A OG GLN 296.A O no hydrogen 2.720 N/A SER 254.A N SER 251.A O no hydrogen 3.151 N/A THR 258.A N GLU 248.A O no hydrogen 3.051 N/A THR 258.A OG1 PRO 245.A O no hydrogen 2.676 N/A THR 258.A OG1 GLU 248.A O no hydrogen 3.460 N/A THR 262.A N ILE 244.A O no hydrogen 2.907 N/A THR 262.A OG1 ARG 260.A O no hydrogen 2.870 N/A ILE 264.A N LYS 242.A O no hydrogen 2.842 N/A GLY 265.A N VAL 301.A O no hydrogen 2.805 N/A THR 266.A N PHE 240.A O no hydrogen 2.810 N/A ILE 269.A N LEU 267.A O no hydrogen 2.957 N/A GLY 270.A N ASP 273.A OD2 no hydrogen 3.127 N/A TYR 271.A N ALA 298.A O no hydrogen 3.121 N/A ASP 273.A N GLY 270.A O no hydrogen 3.050 N/A GLY 274.A N TYR 271.A O no hydrogen 2.994 N/A TRP 275.A N GLY 270.A O no hydrogen 3.263 N/A GLU 278.A N GLU 278.A OE2 no hydrogen 2.816 N/A TYR 279.A N LEU 276.A O no hydrogen 2.963 N/A GLN 280.A N ALA 277.A O no hydrogen 3.214 N/A PHE 282.A N TYR 279.A O no hydrogen 3.160 N/A LEU 284.A N CYS 291.A O no hydrogen 2.759 N/A LEU 285.A N THR 314.A O no hydrogen 2.851 N/A ILE 286.A N GLN 289.A O no hydrogen 2.993 N/A GLY 288.A N SER 319.A OG no hydrogen 2.960 N/A GLN 289.A N ILE 286.A O no hydrogen 2.993 N/A CYS 291.A N LEU 284.A O no hydrogen 2.719 N/A CYS 291.A SG GLN 289.A O no hydrogen 3.721 N/A ARG 292.A NE ASP 281.A OD1 no hydrogen 2.910 N/A ARG 292.A NH2 ASP 281.A OD1 no hydrogen 2.994 N/A GLN 293.A N PHE 282.A O no hydrogen 3.017 N/A GLN 293.A NE2 GLY 295.A O no hydrogen 3.023 N/A ALA 298.A N GLN 300.A O no hydrogen 2.973 N/A ALA 302.A N ARG 292.A O no hydrogen 2.897 N/A LEU 303.A N TRP 263.A O no hydrogen 2.819 N/A HIS 305.A ND1 GLU 306.A O no hydrogen 2.945 N/A TYR 307.A OH ASP 287.A OD2 no hydrogen 3.118 N/A GLY 310.A N LEU 238.A O no hydrogen 2.773 N/A THR 311.A N PRO 308.A O no hydrogen 3.350 N/A THR 311.A OG1 PRO 308.A O no hydrogen 2.736 N/A VAL 313.A N SER 236.A O no hydrogen 2.901 N/A THR 314.A N LEU 285.A O no hydrogen 2.749 N/A LEU 315.A N LEU 234.A O no hydrogen 2.843 N/A ILE 316.A N LEU 234.A O no hydrogen 3.255 N/A GLY 317.A N ASN 324.A O no hydrogen 2.880 N/A LYS 318.A N GLU 233.A OE2 no hydrogen 2.821 N/A LYS 318.A NZ GLU 323.A OE1 no hydrogen 3.257 N/A LYS 318.A NZ GLU 323.A OE2 no hydrogen 2.974 N/A SER 319.A N TYR 322.A O no hydrogen 2.974 N/A TYR 322.A N SER 319.A O no hydrogen 3.146 N/A ASN 324.A N GLY 317.A O no hydrogen 2.863 N/A ASN 324.A ND2 GLN 283.A O no hydrogen 2.819 N/A ASN 324.A ND2 LEU 315.A O no hydrogen 3.055 N/A THR 325.A N ASP 328.A OD2 no hydrogen 2.983 N/A ASP 328.A N THR 325.A OG1 no hydrogen 3.120 N/A LEU 329.A N THR 325.A O no hydrogen 3.118 N/A HIS 330.A N LEU 326.A O no hydrogen 2.920 N/A HIS 330.A ND1 GLU 219.A OE1 no hydrogen 2.653 N/A LYS 331.A N TYR 327.A O no hydrogen 2.951 N/A HIS 332.A N ASP 328.A O no hydrogen 3.122 N/A SER 333.A N LEU 329.A O no hydrogen 2.923 N/A SER 333.A OG LEU 329.A O no hydrogen 2.711 N/A GLY 334.A N HIS 330.A O no hydrogen 2.740 N/A VAL 335.A N SER 333.A OG no hydrogen 3.239 N/A LYS 339.A N PRO 336.A O no hydrogen 2.985 N/A ILE 340.A N PRO 336.A O no hydrogen 2.909 N/A ILE 340.A N PRO 337.A O no hydrogen 3.204 N/A THR 341.A N PRO 337.A O no hydrogen 3.127 N/A THR 341.A OG1 TYR 42.A O no hydrogen 2.805 N/A THR 341.A OG1 PRO 337.A O no hydrogen 3.446 N/A THR 341.A OG1 TRP 338.A O no hydrogen 3.379 N/A VAL 342.A N TRP 338.A O no hydrogen 3.239 N/A ALA 343.A N ILE 340.A O no hydrogen 3.308 N/A PHE 344.A N THR 341.A O no hydrogen 3.187 N/A SER 345.A N ASP 273.A O no hydrogen 3.006 N/A SER 345.A OG GLY 272.A O no hydrogen 2.872 N/A ARG 347.A N SER 345.A OG no hydrogen 3.337 N/A ARG 347.A NE ASP 273.A OD1 no hydrogen 2.896 N/A ARG 347.A NH1 ASP 299.A OD1 no hydrogen 2.727 N/A ARG 347.A NH2 ASP 273.A OD2 no hydrogen 2.944 N/A ARG 347.A NH2 ASP 299.A OD1 no hydrogen 3.000 N/A LEU 348.A N SER 345.A O no hydrogen 3.321 N/A LYS 349.A NZ ILE 4.A O no hydrogen 3.316 N/A LYS 349.A NZ ARG 6.A O no hydrogen 2.852 N/A ARG 350.A N GLU 2.A OE2 no hydrogen 3.168 N/A ARG 350.A NE GLY 43.A O no hydrogen 2.989 N/A ARG 350.A NH1 SER 345.A O no hydrogen 2.885 N/A ARG 350.A NH2 GLY 43.A O no hydrogen 2.813 N/A ARG 350.A NH2 PHE 344.A O no hydrogen 3.156 N/A ARG 350.A NH2 SER 345.A O no hydrogen 3.245 N/A VAL 352.A N PHE 12.A O no hydrogen 2.630 N/A