Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3cz7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 4.A OD2 no hydrogen 3.219 N/A LEU 2.A N ASP 304.A OD1 no hydrogen 2.893 N/A ASN 3.A ND2 GLN 351.A OE1 no hydrogen 3.638 N/A ASN 3.A ND2 SER 352.A O no hydrogen 2.986 N/A ASP 4.A N SER 1.A OG no hydrogen 3.003 N/A PHE 5.A N SER 1.A O no hydrogen 2.916 N/A LEU 6.A N LEU 2.A O no hydrogen 2.888 N/A SER 7.A N ASN 3.A O no hydrogen 2.956 N/A SER 7.A OG ASN 3.A O no hydrogen 2.819 N/A SER 7.A OG ASN 3.A OD1 no hydrogen 3.290 N/A SER 7.A OG THR 354.A O no hydrogen 3.538 N/A SER 8.A N ASP 4.A O no hydrogen 3.079 N/A SER 8.A N PHE 5.A O no hydrogen 3.216 N/A SER 8.A OG PHE 5.A O no hydrogen 2.530 N/A VAL 9.A N LEU 6.A O no hydrogen 3.092 N/A LEU 10.A N SER 7.A O no hydrogen 3.382 N/A VAL 12.A N ARG 357.A O no hydrogen 2.907 N/A SER 13.A N GLY 355.A O no hydrogen 2.982 N/A GLU 14.A N PRO 11.A O no hydrogen 3.120 N/A GLN 15.A NE2 SER 13.A O no hydrogen 3.139 N/A PHE 16.A N LEU 353.A O no hydrogen 3.033 N/A GLU 17.A N PHE 55.A O no hydrogen 3.093 N/A TYR 18.A N GLN 351.A O no hydrogen 2.929 N/A TYR 18.A OH ALA 303.A O no hydrogen 2.854 N/A LEU 19.A N SER 53.A O no hydrogen 2.842 N/A SER 20.A OG ASP 304.A O no hydrogen 2.647 N/A LEU 21.A N PHE 51.A O no hydrogen 2.760 N/A GLN 22.A N ILE 306.A O no hydrogen 2.953 N/A GLN 22.A NE2 SER 23.A O no hydrogen 3.151 N/A SER 23.A N GLN 49.A O no hydrogen 3.043 N/A LEU 26.A N LYS 47.A O no hydrogen 3.017 N/A GLU 27.A N LYS 123.A O no hydrogen 2.896 N/A THR 28.A N THR 45.A O no hydrogen 2.794 N/A HIS 29.A ND1 ALA 30.A O no hydrogen 3.125 N/A LYS 36.A NZ ASP 37.A OD2 no hydrogen 3.562 N/A ASP 37.A N ASN 35.A OD1 no hydrogen 3.028 N/A LYS 39.A NZ ASP 38.A OD1 no hydrogen 3.233 N/A ARG 40.A NE LYS 39.A O no hydrogen 3.500 N/A LYS 43.A N LEU 72.A O no hydrogen 2.715 N/A SER 44.A N LEU 72.A O no hydrogen 3.335 N/A ILE 46.A N VAL 70.A O no hydrogen 2.824 N/A LYS 47.A N LEU 26.A O no hydrogen 2.842 N/A THR 48.A N VAL 68.A O no hydrogen 2.922 N/A GLN 49.A N SER 23.A OG no hydrogen 2.870 N/A HIS 50.A N VAL 66.A O no hydrogen 2.684 N/A HIS 50.A NE2 TYR 118.A OH no hydrogen 2.721 N/A PHE 51.A N LEU 21.A O no hydrogen 2.736 N/A PHE 52.A N LEU 64.A O no hydrogen 2.883 N/A SER 53.A N LEU 19.A O no hydrogen 2.906 N/A SER 53.A OG SER 63.A OG no hydrogen 2.901 N/A LEU 54.A N PHE 62.A O no hydrogen 2.979 N/A PHE 55.A N GLU 17.A O no hydrogen 2.869 N/A HIS 56.A N LYS 59.A O no hydrogen 2.976 N/A LYS 59.A N HIS 56.A O no hydrogen 3.202 N/A LYS 59.A NZ GLN 57.A O no hydrogen 3.189 N/A VAL 60.A N ALA 332.A O no hydrogen 3.145 N/A PHE 61.A N LEU 54.A O no hydrogen 2.975 N/A SER 63.A N ASP 88.A O no hydrogen 2.985 N/A SER 63.A OG PHE 52.A O no hydrogen 3.529 N/A SER 63.A OG SER 53.A OG no hydrogen 2.901 N/A SER 63.A OG PHE 62.A O no hydrogen 2.908 N/A LEU 64.A N PHE 52.A O no hydrogen 2.927 N/A GLU 65.A N LYS 86.A O no hydrogen 2.800 N/A VAL 66.A N HIS 50.A O no hydrogen 2.956 N/A TYR 67.A N PHE 83.A O no hydrogen 2.913 N/A VAL 68.A N THR 48.A O no hydrogen 2.717 N/A TYR 69.A N LEU 81.A O no hydrogen 2.862 N/A VAL 70.A N ILE 46.A O no hydrogen 2.917 N/A THR 71.A N GLU 79.A O no hydrogen 2.898 N/A LEU 72.A N SER 44.A O no hydrogen 2.793 N/A TRP 73.A N ASP 77.A O no hydrogen 2.771 N/A ASP 74.A N ASP 77.A O no hydrogen 3.295 N/A ALA 76.A N ASP 74.A OD1 no hydrogen 2.714 N/A ASP 77.A N ASP 74.A O no hydrogen 3.285 N/A GLU 79.A N THR 71.A O no hydrogen 3.054 N/A ARG 80.A N LEU 146.A O no hydrogen 2.934 N/A ARG 80.A NE THR 147.A OG1 no hydrogen 2.816 N/A ARG 80.A NH1 LEU 111.A O no hydrogen 2.950 N/A ARG 80.A NH2 LEU 111.A O no hydrogen 2.898 N/A ARG 80.A NH2 THR 147.A OG1 no hydrogen 3.316 N/A LEU 81.A N TYR 69.A O no hydrogen 2.759 N/A ILE 82.A N LYS 148.A O no hydrogen 2.733 N/A PHE 83.A N TYR 67.A O no hydrogen 2.792 N/A VAL 84.A N CYS 150.A O no hydrogen 3.064 N/A SER 85.A N GLU 65.A O no hydrogen 2.971 N/A SER 85.A OG GLU 65.A OE2 no hydrogen 2.729 N/A LYS 86.A N GLU 65.A O no hydrogen 3.328 N/A LYS 86.A NZ ASP 245.A OD2 no hydrogen 2.634 N/A ASP 88.A N SER 63.A O no hydrogen 3.014 N/A THR 89.A N ASP 88.A OD1 no hydrogen 2.939 N/A ASN 90.A N PHE 61.A O no hydrogen 3.265 N/A ASN 90.A ND2 VAL 60.A O no hydrogen 2.966 N/A TYR 92.A N ASN 90.A OD1 no hydrogen 2.959 N/A TYR 92.A OH TYR 326.A O no hydrogen 2.691 N/A CYS 93.A SG THR 95.A O no hydrogen 3.306 N/A THR 95.A OG1 GLU 14.A OE1 no hydrogen 2.531 N/A THR 95.A OG1 GLU 14.A OE2 no hydrogen 3.483 N/A ARG 100.A NE ASP 101.A OD1 no hydrogen 3.195 N/A ARG 100.A NH1 ASP 101.A OD1 no hydrogen 3.005 N/A ASP 101.A N SER 98.A OG no hydrogen 3.133 N/A ILE 102.A N SER 98.A O no hydrogen 3.020 N/A THR 103.A N VAL 99.A O no hydrogen 2.902 N/A THR 103.A OG1 VAL 99.A O no hydrogen 2.803 N/A LYS 104.A N ARG 100.A O no hydrogen 2.901 N/A LYS 104.A NZ GLU 191.A OE1 no hydrogen 3.506 N/A LYS 104.A NZ GLU 191.A OE2 no hydrogen 3.294 N/A ILE 105.A N ASP 101.A O no hydrogen 2.865 N/A ILE 106.A N ILE 102.A O no hydrogen 3.018 N/A LEU 107.A N THR 103.A O no hydrogen 3.141 N/A GLU 108.A N LYS 104.A O no hydrogen 2.940 N/A PHE 109.A N ILE 105.A O no hydrogen 2.905 N/A ILE 110.A N ILE 106.A O no hydrogen 2.951 N/A LEU 111.A N LEU 107.A O no hydrogen 2.858 N/A SER 112.A N GLU 108.A O no hydrogen 3.240 N/A SER 112.A N PHE 109.A O no hydrogen 3.079 N/A SER 112.A OG PHE 109.A O no hydrogen 2.712 N/A ILE 113.A N ILE 110.A O no hydrogen 3.108 N/A ASP 114.A N LEU 298.A O no hydrogen 2.834 N/A ASN 116.A N ASP 114.A OD1 no hydrogen 2.762 N/A ASN 116.A ND2 ASP 114.A OD1 no hydrogen 2.850 N/A ASN 116.A ND2 CYS 141.A O no hydrogen 2.871 N/A TYR 117.A N ASP 114.A O no hydrogen 2.824 N/A TYR 117.A OH GLN 22.A OE1 no hydrogen 2.577 N/A TYR 118.A N PRO 115.A O no hydrogen 3.167 N/A TYR 118.A OH HIS 50.A NE2 no hydrogen 2.721 N/A LEU 119.A N ASN 116.A O no hydrogen 3.006 N/A GLN 120.A NE2 TYR 117.A O no hydrogen 3.125 N/A VAL 122.A N LEU 137.A O no hydrogen 2.778 N/A LYS 123.A N PRO 25.A O no hydrogen 2.864 N/A LYS 123.A NZ TYR 136.A OH no hydrogen 3.316 N/A ALA 125.A N GLU 27.A OE1 no hydrogen 2.952 N/A LEU 137.A N VAL 122.A O no hydrogen 2.728 N/A PHE 139.A N LEU 119.A O no hydrogen 2.913 N/A CYS 141.A N ASN 116.A OD1 no hydrogen 2.929 N/A CYS 141.A SG PRO 142.A O no hydrogen 3.362 N/A ARG 143.A NE ASP 114.A OD2 no hydrogen 2.957 N/A THR 147.A N GLY 290.A O no hydrogen 2.766 N/A THR 147.A OG1 ILE 145.A O no hydrogen 2.920 N/A LYS 148.A N ARG 80.A O no hydrogen 2.797 N/A LYS 148.A NZ GLU 79.A OE1 no hydrogen 2.910 N/A ILE 149.A N ILE 288.A O no hydrogen 2.970 N/A CYS 150.A N ILE 82.A O no hydrogen 2.955 N/A THR 153.A N SER 285.A O no hydrogen 2.746 N/A THR 153.A OG1 SER 285.A OG no hydrogen 2.772 N/A TYR 159.A N ASP 88.A OD2 no hydrogen 2.768 N/A TYR 159.A OH ARG 154.A O no hydrogen 2.623 N/A LEU 160.A N ASP 88.A OD2 no hydrogen 2.823 N/A PHE 161.A N ASP 88.A OD2 no hydrogen 3.178 N/A SER 164.A N PHE 161.A O no hydrogen 3.087 N/A SER 164.A OG PHE 161.A O no hydrogen 2.686 N/A LYS 166.A N ASP 163.A O no hydrogen 3.122 N/A ASN 167.A N SER 164.A O no hydrogen 2.992 N/A ASN 167.A ND2 ASN 90.A O no hydrogen 2.744 N/A LYS 169.A N ASN 167.A OD1 no hydrogen 2.941 N/A LYS 170.A N ASN 167.A O no hydrogen 3.019 N/A LYS 170.A NZ ASP 88.A OD1 no hydrogen 2.755 N/A LYS 170.A NZ THR 89.A O no hydrogen 2.829 N/A LYS 170.A NZ SER 157.A O no hydrogen 2.741 N/A LYS 170.A NZ SER 164.A OG no hydrogen 2.904 N/A ASN 174.A N GLU 177.A OE1 no hydrogen 2.979 N/A GLU 177.A N ASN 174.A OD1 no hydrogen 2.957 N/A LEU 178.A N ASN 174.A O no hydrogen 2.891 N/A TRP 180.A N GLU 177.A O no hydrogen 2.909 N/A TRP 181.A N LEU 178.A O no hydrogen 3.094 N/A PHE 183.A N LYS 179.A O no hydrogen 2.971 N/A ILE 184.A N TRP 180.A O no hydrogen 3.167 N/A LEU 185.A N TRP 181.A O no hydrogen 2.895 N/A ASP 186.A N GLY 182.A O no hydrogen 2.915 N/A ARG 187.A N PHE 183.A O no hydrogen 3.016 N/A ARG 187.A NE GLU 191.A OE2 no hydrogen 2.913 N/A ARG 187.A NH2 GLU 191.A OE2 no hydrogen 2.937 N/A LEU 188.A N ILE 184.A O no hydrogen 2.984 N/A LEU 189.A N LEU 185.A O no hydrogen 2.877 N/A ILE 190.A N ASP 186.A O no hydrogen 3.092 N/A GLU 191.A N ARG 187.A O no hydrogen 2.769 N/A CYS 192.A N LEU 188.A O no hydrogen 2.786 N/A PHE 193.A N LEU 189.A O no hydrogen 3.117 N/A GLN 194.A N TYR 291.A O no hydrogen 2.912 N/A GLN 194.A NE2 SER 292.A O no hydrogen 3.480 N/A THR 197.A OG1 GLN 194.A O no hydrogen 2.651 N/A GLN 198.A N SER 289.A O no hydrogen 2.873 N/A LYS 200.A N GLY 287.A O no hydrogen 2.793 N/A LYS 200.A NZ GLN 198.A OE1 no hydrogen 2.855 N/A LYS 200.A NZ ASP 226.A O no hydrogen 3.231 N/A LEU 201.A N GLN 223.A O no hydrogen 3.111 N/A ARG 202.A N VAL 286.A O no hydrogen 2.956 N/A ARG 202.A NE ASP 226.A OD2 no hydrogen 3.004 N/A ARG 202.A NH1 ASP 226.A OD2 no hydrogen 2.837 N/A GLU 206.A N ILE 203.A O no hydrogen 2.901 N/A ALA 209.A N ASP 207.A OD1 no hydrogen 2.832 N/A ARG 210.A NE ASP 207.A O no hydrogen 3.001 N/A ARG 212.A N PRO 208.A O no hydrogen 2.835 N/A SER 213.A N ALA 209.A O no hydrogen 3.150 N/A TYR 214.A N ARG 210.A O no hydrogen 3.488 N/A LEU 215.A N VAL 211.A O no hydrogen 3.273 N/A ARG 216.A N SER 213.A O no hydrogen 3.254 N/A GLY 217.A N TYR 214.A O no hydrogen 2.987 N/A LYS 218.A N ASP 186.A OD1 no hydrogen 3.380 N/A LYS 218.A N ASP 186.A OD2 no hydrogen 2.664 N/A TYR 219.A N ASP 186.A OD1 no hydrogen 2.803 N/A TYR 219.A OH ASN 195.A O no hydrogen 3.423 N/A TYR 219.A OH THR 197.A O no hydrogen 2.550 N/A TRP 222.A NE1 ASP 186.A OD1 no hydrogen 2.990 N/A GLN 223.A N ALA 199.A O no hydrogen 2.775 N/A GLY 225.A N LEU 201.A O no hydrogen 2.765 N/A PHE 228.A N ASP 226.A OD1 no hydrogen 2.875 N/A THR 229.A OG1 ASN 239.A OD1 no hydrogen 2.597 N/A LYS 231.A N ASN 239.A OD1 no hydrogen 2.705 N/A LYS 231.A NZ THR 229.A OG1 no hydrogen 3.040 N/A LEU 235.A N GLU 232.A O no hydrogen 3.063 N/A ALA 236.A N VAL 263.A O no hydrogen 2.962 N/A TYR 238.A N LEU 235.A O no hydrogen 3.224 N/A ASN 239.A N ALA 236.A O no hydrogen 2.948 N/A ASN 239.A ND2 LYS 231.A O no hydrogen 2.863 N/A ASN 239.A ND2 LEU 235.A O no hydrogen 2.759 N/A ILE 240.A N ALA 236.A O no hydrogen 2.888 N/A LEU 242.A N VAL 31.A O no hydrogen 2.969 N/A ASP 246.A N PHE 243.A O no hydrogen 3.278 N/A ARG 249.A N ASP 246.A O no hydrogen 2.999 N/A ARG 249.A NH2 ASP 245.A O no hydrogen 2.948 N/A PHE 250.A N PRO 247.A O no hydrogen 3.015 N/A HIS 252.A N ALA 248.A O no hydrogen 2.987 N/A GLN 253.A N ARG 249.A O no hydrogen 3.059 N/A LEU 254.A N PHE 250.A O no hydrogen 2.938 N/A ALA 255.A N ILE 251.A O no hydrogen 2.862 N/A GLU 256.A N HIS 252.A O no hydrogen 2.917 N/A GLU 257.A N GLN 253.A O no hydrogen 3.030 N/A ASP 258.A N ALA 255.A O no hydrogen 3.009 N/A ARG 259.A N LEU 254.A O no hydrogen 2.945 N/A ARG 259.A NH1 GLU 257.A OE1 no hydrogen 3.254 N/A ARG 259.A NH1 GLU 271.A OE1 no hydrogen 2.886 N/A ARG 259.A NH2 GLU 271.A OE1 no hydrogen 3.058 N/A ARG 259.A NH2 GLU 271.A OE2 no hydrogen 2.812 N/A LYS 262.A N ARG 259.A O no hydrogen 2.865 N/A SER 264.A OG SER 266.A OG no hydrogen 3.029 N/A SER 264.A OG SER 267.A OG no hydrogen 3.224 N/A LEU 265.A N SER 234.A O no hydrogen 2.692 N/A SER 266.A OG SER 264.A OG no hydrogen 3.029 N/A SER 267.A N SER 264.A OG no hydrogen 3.159 N/A SER 267.A OG SER 264.A OG no hydrogen 3.224 N/A PHE 268.A N SER 264.A O no hydrogen 2.862 N/A TRP 269.A N LEU 265.A O no hydrogen 3.195 N/A ILE 270.A N SER 266.A O no hydrogen 3.408 N/A GLU 271.A N SER 267.A O no hydrogen 2.722 N/A LEU 272.A N PHE 268.A O no hydrogen 2.724 N/A GLN 273.A N ILE 270.A O no hydrogen 3.242 N/A GLN 273.A NE2 GLU 277.A OE1 no hydrogen 3.470 N/A GLU 274.A N ILE 270.A O no hydrogen 2.767 N/A ARG 275.A N GLU 271.A O no hydrogen 3.113 N/A ARG 275.A NH1 GLU 257.A OE1 no hydrogen 3.080 N/A ARG 275.A NH2 GLU 257.A OE1 no hydrogen 2.994 N/A GLN 276.A N GLN 273.A O no hydrogen 3.228 N/A SER 281.A N PHE 278.A O no hydrogen 2.829 N/A SER 281.A OG PHE 278.A O no hydrogen 2.735 N/A THR 283.A OG1 GLU 176.A OE1 no hydrogen 3.413 N/A SER 284.A OG VAL 282.A O no hydrogen 3.486 N/A SER 285.A N THR 153.A O no hydrogen 3.097 N/A SER 285.A OG THR 153.A OG1 no hydrogen 2.772 N/A VAL 286.A N ARG 202.A O no hydrogen 2.928 N/A ILE 288.A N ILE 149.A O no hydrogen 2.880 N/A SER 289.A N GLN 198.A O no hydrogen 2.955 N/A GLY 290.A N THR 147.A O no hydrogen 2.954 N/A LEU 293.A N CYS 192.A O no hydrogen 2.828 N/A LEU 298.A N SER 112.A O no hydrogen 3.226 N/A SER 301.A N ASP 304.A OD2 no hydrogen 3.031 N/A ALA 303.A N SER 301.A OG no hydrogen 3.061 N/A ASP 304.A N SER 301.A OG no hydrogen 3.104 N/A VAL 305.A N SER 301.A O no hydrogen 3.087 N/A ILE 306.A N SER 20.A O no hydrogen 2.764 N/A GLN 313.A N SER 310.A OG no hydrogen 3.166 N/A PHE 314.A N SER 310.A O no hydrogen 3.087 N/A ARG 315.A N ARG 311.A O no hydrogen 2.744 N/A ALA 316.A N LYS 312.A O no hydrogen 2.930 N/A ILE 317.A N GLN 313.A O no hydrogen 3.086 N/A LYS 318.A N PHE 314.A O no hydrogen 2.980 N/A LYS 318.A NZ GLN 49.A OE1 no hydrogen 2.620 N/A LYS 318.A NZ GLU 65.A OE1 no hydrogen 2.667 N/A LYS 319.A N ARG 315.A O no hydrogen 2.863 N/A TYR 320.A N ALA 316.A O no hydrogen 3.333 N/A TYR 320.A N ILE 317.A O no hydrogen 3.187 N/A ILE 321.A N LYS 318.A O no hydrogen 2.990 N/A THR 322.A N LYS 318.A O no hydrogen 3.076 N/A THR 322.A OG1 LYS 318.A O no hydrogen 3.495 N/A GLY 323.A N LYS 319.A O no hydrogen 2.750 N/A GLU 324.A N ILE 321.A O no hydrogen 3.493 N/A GLU 325.A N GLU 324.A OE2 no hydrogen 3.251 N/A TYR 326.A N PRO 162.A O no hydrogen 2.798 N/A TYR 326.A OH ILE 321.A O no hydrogen 2.595 N/A GLU 330.A N THR 328.A OG1 no hydrogen 3.269 N/A GLY 331.A N THR 328.A O no hydrogen 3.170 N/A ILE 333.A N GLU 329.A O no hydrogen 3.056 N/A GLU 334.A N GLU 330.A O no hydrogen 2.815 N/A ALA 335.A N GLY 331.A O no hydrogen 2.923 N/A PHE 336.A N ALA 332.A O no hydrogen 3.360 N/A THR 337.A N ILE 333.A O no hydrogen 2.943 N/A THR 337.A OG1 GLU 334.A O no hydrogen 3.327 N/A ASN 338.A N GLU 334.A O no hydrogen 2.877 N/A ASN 338.A ND2 GLU 334.A OE2 no hydrogen 3.056 N/A ILE 339.A N ALA 335.A O no hydrogen 3.084 N/A ARG 340.A N PHE 336.A O no hydrogen 2.909 N/A ARG 340.A NE ASP 341.A OD1 no hydrogen 3.214 N/A ARG 340.A NH2 ASP 341.A OD1 no hydrogen 2.779 N/A ASP 341.A N THR 337.A O no hydrogen 2.906 N/A PHE 342.A N ASN 338.A O no hydrogen 2.906 N/A LEU 343.A N ILE 339.A O no hydrogen 2.946 N/A LEU 344.A N ARG 340.A O no hydrogen 3.129 N/A LEU 345.A N ASP 341.A O no hydrogen 2.732 N/A ARG 346.A N PHE 342.A O no hydrogen 2.758 N/A THR 348.A N LEU 343.A O no hydrogen 2.846 N/A GLN 351.A N TYR 18.A O no hydrogen 3.200 N/A LEU 353.A N PHE 16.A O no hydrogen 2.790 N/A THR 354.A OG1 GLN 15.A OE1 no hydrogen 2.856 N/A GLY 355.A N GLU 14.A O no hydrogen 2.814 N/A LYS 356.A N SER 7.A O no hydrogen 2.789 N/A ARG 357.A N LEU 10.A O no hydrogen 2.858 N/A ARG 357.A NH1 ASP 101.A OD2 no hydrogen 2.686 N/A ARG 357.A NH2 ASP 101.A OD2 no hydrogen 2.641 N/A GLY 128B.A N ILE 126.A O no hydrogen 2.383 N/A