Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3czb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N TYR 319.A OH no hydrogen 3.031 N/A GLY 9.A N SER 6.A O no hydrogen 3.252 N/A LEU 10.A N PHE 7.A O no hydrogen 3.206 N/A TRP 13.A N LEU 10.A O no hydrogen 3.092 N/A TRP 13.A NE1 GLU 60.A OE2 no hydrogen 2.893 N/A GLU 15.A N GLY 12.A O no hydrogen 3.192 N/A GLU 16.A N TRP 13.A O no hydrogen 3.016 N/A HIS 18.A NE2 TRP 13.A O no hydrogen 2.657 N/A ALA 20.A N ASP 17.A OD1 no hydrogen 3.380 N/A ALA 21.A N ASP 17.A O no hydrogen 3.014 N/A LEU 22.A N HIS 18.A O no hydrogen 2.938 N/A ASN 23.A N LEU 19.A O no hydrogen 2.848 N/A ALA 24.A N ALA 20.A O no hydrogen 2.852 N/A ALA 24.A N ALA 21.A O no hydrogen 3.040 N/A PHE 25.A N ALA 21.A O no hydrogen 3.094 N/A ARG 26.A N LEU 22.A O no hydrogen 3.042 N/A ARG 26.A NE ALA 44.A O no hydrogen 2.955 N/A ARG 26.A NH1 ASN 23.A OD1 no hydrogen 2.805 N/A ARG 26.A NH2 ALA 44.A O no hydrogen 3.273 N/A ALA 27.A N ASN 23.A O no hydrogen 2.795 N/A GLY 28.A N PHE 25.A O no hydrogen 3.100 N/A CYS 29.A N PHE 25.A O no hydrogen 2.816 N/A CYS 29.A SG PHE 25.A O no hydrogen 3.463 N/A CYS 29.A SG ARG 26.A O no hydrogen 3.993 N/A VAL 31.A N GLY 28.A O no hydrogen 3.245 N/A SER 32.A N CYS 29.A O no hydrogen 2.756 N/A ALA 36.A N ASP 34.A OD1 no hydrogen 2.569 N/A ALA 37.A N ASP 34.A OD1 no hydrogen 3.246 N/A ALA 38.A N PRO 35.A O no hydrogen 3.076 N/A ARG 39.A N PRO 35.A O no hydrogen 3.395 N/A CYS 41.A N ALA 37.A O no hydrogen 2.929 N/A GLY 42.A N ALA 38.A O no hydrogen 2.825 N/A LEU 43.A N ARG 39.A O no hydrogen 2.903 N/A ALA 44.A N VAL 40.A O no hydrogen 2.807 N/A LYS 45.A N CYS 41.A O no hydrogen 3.040 N/A ALA 46.A N GLY 42.A O no hydrogen 3.170 N/A THR 47.A N LEU 43.A O no hydrogen 2.896 N/A GLY 54.A N ASP 51.A OD2 no hydrogen 2.861 N/A ALA 55.A N ASP 51.A O no hydrogen 3.118 N/A LYS 56.A N VAL 52.A O no hydrogen 3.075 N/A LYS 56.A NZ GLU 60.A OE2 no hydrogen 3.447 N/A ALA 57.A N SER 53.A O no hydrogen 3.190 N/A PHE 58.A N GLY 54.A O no hydrogen 2.658 N/A ILE 59.A N ALA 55.A O no hydrogen 3.037 N/A GLU 60.A N LYS 56.A O no hydrogen 3.006 N/A ALA 61.A N ALA 57.A O no hydrogen 3.041 N/A ALA 61.A N PHE 58.A O no hydrogen 3.197 N/A ASN 62.A N ILE 59.A O no hydrogen 3.307 N/A ASN 62.A ND2 PHE 58.A O no hydrogen 2.875 N/A PHE 63.A N ILE 59.A O no hydrogen 3.073 N/A ARG 64.A N THR 322.A O no hydrogen 2.782 N/A GLU 66.A N ARG 320.A O no hydrogen 2.984 N/A VAL 68.A N LEU 318.A O no hydrogen 2.902 N/A GLY 71.A N VAL 68.A O no hydrogen 2.915 N/A GLY 72.A N ASP 69.A O no hydrogen 3.234 N/A GLY 74.A N LEU 316.A O no hydrogen 2.844 N/A LEU 75.A N VAL 293.A O no hydrogen 3.128 N/A LEU 76.A N HIS 314.A O no hydrogen 2.711 N/A THR 77.A N ALA 295.A O no hydrogen 3.189 N/A THR 77.A OG1 ASP 296.A OD1 no hydrogen 2.522 N/A TYR 79.A N LEU 297.A O no hydrogen 2.920 N/A TYR 79.A OH ASP 284.A OD2 no hydrogen 2.703 N/A ALA 81.A N GLY 300.A O no hydrogen 2.625 N/A TYR 84.A N VAL 167.A O no hydrogen 2.641 N/A ALA 86.A N VAL 169.A O no hydrogen 3.033 N/A ARG 87.A N TRP 151.A O no hydrogen 2.983 N/A ASN 91.A N PHE 94.A O no hydrogen 3.352 N/A GLU 93.A N ASN 91.A OD1 no hydrogen 3.016 N/A PHE 94.A N ASN 91.A OD1 no hydrogen 2.682 N/A ALA 96.A N MET 152.A O no hydrogen 2.972 N/A LEU 98.A N ALA 150.A O no hydrogen 3.005 N/A ARG 99.A NH1 THR 143.A O no hydrogen 3.508 N/A ARG 99.A NH2 THR 143.A O no hydrogen 2.541 N/A LEU 105.A N PRO 102.A O no hydrogen 3.193 N/A VAL 106.A N GLY 124.A O no hydrogen 2.863 N/A LEU 108.A N ILE 122.A O no hydrogen 2.827 N/A LEU 110.A N LYS 120.A O no hydrogen 3.080 N/A GLY 111.A N ASP 109.A OD2 no hydrogen 3.241 N/A PHE 113.A N LEU 110.A O no hydrogen 3.162 N/A GLU 114.A N LEU 110.A O no hydrogen 3.328 N/A GLU 114.A N GLY 111.A O no hydrogen 3.251 N/A LEU 117.A N GLU 114.A O no hydrogen 2.825 N/A VAL 118.A N PRO 115.A O no hydrogen 3.053 N/A LYS 120.A N LEU 117.A O no hydrogen 2.934 N/A LYS 121.A NZ ASP 109.A OD1 no hydrogen 3.396 N/A ILE 122.A N LEU 108.A O no hydrogen 3.269 N/A GLY 124.A N VAL 106.A O no hydrogen 2.993 N/A HIS 125.A N VAL 132.A O no hydrogen 2.943 N/A GLU 127.A N THR 130.A O no hydrogen 3.038 N/A THR 130.A N GLU 127.A O no hydrogen 3.423 N/A THR 130.A OG1 PHE 131.A O no hydrogen 3.511 N/A PHE 131.A N THR 130.A OG1 no hydrogen 2.515 N/A VAL 132.A N HIS 125.A O no hydrogen 3.071 N/A TYR 134.A N THR 123.A O no hydrogen 3.287 N/A TYR 134.A OH ASP 104.A OD1 no hydrogen 2.880 N/A ARG 137.A N PRO 225.A O no hydrogen 2.961 N/A ARG 137.A NE ASN 224.A O no hydrogen 2.920 N/A ARG 137.A NH1 GLU 141.A OE2 no hydrogen 3.315 N/A ARG 137.A NH1 GLN 161.A OE1 no hydrogen 2.698 N/A ARG 137.A NH2 GLN 161.A OE1 no hydrogen 3.000 N/A GLU 139.A N ASP 136.A OD1 no hydrogen 3.177 N/A ILE 140.A N ASP 136.A O no hydrogen 2.848 N/A GLU 141.A N ARG 137.A O no hydrogen 2.748 N/A ALA 142.A N GLU 139.A O no hydrogen 3.385 N/A THR 143.A N ILE 140.A O no hydrogen 3.371 N/A THR 143.A OG1 ILE 140.A O no hydrogen 3.402 N/A LEU 149.A N LEU 98.A O no hydrogen 2.694 N/A TRP 151.A N ARG 87.A O no hydrogen 2.890 N/A MET 152.A N ALA 96.A O no hydrogen 2.820 N/A ARG 153.A NE GLU 93.A OE2 no hydrogen 2.431 N/A ARG 153.A NH1 GLU 85.A OE2 no hydrogen 3.277 N/A ARG 153.A NH1 GLU 156.A OE1 no hydrogen 3.243 N/A ARG 153.A NH2 GLU 93.A OE2 no hydrogen 2.451 N/A GLU 156.A N ARG 153.A O no hydrogen 2.817 N/A LEU 157.A N ARG 153.A O no hydrogen 2.902 N/A PHE 158.A N PRO 154.A O no hydrogen 2.905 N/A PHE 159.A N GLU 155.A O no hydrogen 3.149 N/A LEU 160.A N GLU 156.A O no hydrogen 2.836 N/A GLN 161.A N LEU 157.A O no hydrogen 2.708 N/A GLN 161.A NE2 VAL 228.A O no hydrogen 3.153 N/A ILE 162.A N PHE 158.A O no hydrogen 3.345 N/A GLN 163.A N PHE 159.A O no hydrogen 3.081 N/A GLY 164.A N LEU 160.A O no hydrogen 2.771 N/A GLY 166.A N ALA 178.A O no hydrogen 3.310 N/A VAL 167.A N PRO 82.A O no hydrogen 3.223 N/A LEU 168.A N VAL 176.A O no hydrogen 2.770 N/A VAL 169.A N TYR 84.A O no hydrogen 2.690 N/A LEU 170.A N ARG 174.A O no hydrogen 3.118 N/A GLY 173.A N LEU 170.A O no hydrogen 2.806 N/A ARG 174.A N ASP 172.A OD2 no hydrogen 2.909 N/A ARG 174.A NE ASP 172.A OD1 no hydrogen 3.125 N/A ARG 174.A NE ASP 172.A OD2 no hydrogen 3.151 N/A ARG 174.A NH2 ASP 172.A OD1 no hydrogen 3.032 N/A ARG 175.A NE ASP 235.A OD2 no hydrogen 2.727 N/A ARG 175.A NH1 ASP 235.A OD2 no hydrogen 2.747 N/A VAL 176.A N LEU 168.A O no hydrogen 2.895 N/A ARG 177.A N VAL 233.A O no hydrogen 2.781 N/A ARG 177.A NH1 LYS 238.A O no hydrogen 2.997 N/A ARG 177.A NH2 LYS 238.A O no hydrogen 2.426 N/A ALA 178.A N GLY 166.A O no hydrogen 2.956 N/A VAL 179.A N ARG 231.A O no hydrogen 2.710 N/A ALA 181.A N PHE 229.A O no hydrogen 2.763 N/A GLY 182.A N PHE 229.A O no hydrogen 3.394 N/A ASN 184.A N TYR 227.A O no hydrogen 3.056 N/A ASN 184.A ND2 PRO 135.A O no hydrogen 3.205 N/A ASN 184.A ND2 PRO 225.A O no hydrogen 2.766 N/A LYS 186.A N ASN 184.A OD1 no hydrogen 3.153 N/A LYS 186.A NZ TYR 134.A O no hydrogen 2.758 N/A VAL 189.A N ASN 224.A OD1 no hydrogen 3.029 N/A MET 195.A N ILE 191.A O no hydrogen 3.102 N/A ARG 196.A N ALA 192.A O no hydrogen 2.913 N/A ASP 197.A N ILE 193.A O no hydrogen 3.136 N/A GLY 199.A N ARG 196.A O no hydrogen 2.805 N/A LEU 200.A N MET 195.A O no hydrogen 3.247 N/A THR 207.A N ASP 203.A O no hydrogen 3.190 N/A THR 207.A OG1 ASP 203.A O no hydrogen 2.445 N/A TRP 208.A N ALA 204.A O no hydrogen 2.812 N/A LEU 209.A N ILE 205.A O no hydrogen 2.875 N/A ALA 210.A N ARG 206.A O no hydrogen 2.903 N/A GLU 211.A N THR 207.A O no hydrogen 2.973 N/A HIS 212.A N LEU 209.A O no hydrogen 3.097 N/A HIS 212.A ND1 TRP 208.A O no hydrogen 2.770 N/A ARG 213.A NE GLU 155.A OE1 no hydrogen 2.547 N/A ARG 213.A NH2 GLU 155.A OE1 no hydrogen 3.309 N/A ALA 217.A N HIS 212.A O no hydrogen 3.346 N/A ASP 218.A N GLY 214.A O no hydrogen 2.532 N/A ALA 219.A N PRO 215.A O no hydrogen 3.100 N/A ILE 220.A N ALA 217.A O no hydrogen 3.032 N/A MET 221.A N ALA 217.A O no hydrogen 3.019 N/A ARG 222.A N ASP 218.A O no hydrogen 3.060 N/A LEU 223.A N ILE 220.A O no hydrogen 3.053 N/A ASN 224.A N MET 221.A O no hydrogen 2.839 N/A ARG 226.A N.A ASN 224.A OD1 no hydrogen 3.483 N/A ARG 226.A NH1.A GLN 161.A O no hydrogen 3.444 N/A ARG 226.A NH1.B LYS 186.A O no hydrogen 2.575 N/A TYR 227.A N ASN 184.A OD1 no hydrogen 3.013 N/A PHE 229.A N GLY 182.A O no hydrogen 2.854 N/A PHE 230.A N ARG 99.A O no hydrogen 2.876 N/A ARG 231.A N VAL 179.A O no hydrogen 2.780 N/A VAL 233.A N ARG 177.A O no hydrogen 3.058 N/A ASP 235.A N ARG 175.A O no hydrogen 3.117 N/A GLY 237.A N ASP 235.A OD1 no hydrogen 2.827 N/A LYS 238.A N ASP 236.A OD1 no hydrogen 3.126 N/A ALA 243.A N ASP 284.A OD1 no hydrogen 2.774 N/A ALA 244.A N LEU 283.A O no hydrogen 3.267 N/A GLY 245.A N GLY 242.A O no hydrogen 2.873 N/A LEU 248.A N PRO 240.A O no hydrogen 3.013 N/A GLY 251.A N TYR 298.A O no hydrogen 2.583 N/A ARG 252.A N PRO 249.A O no hydrogen 3.018 N/A ARG 252.A NH1 GLU 16.A OE1 no hydrogen 3.434 N/A ARG 252.A NH1 GLU 16.A OE2 no hydrogen 2.525 N/A ARG 252.A NH1 ALA 279.A O no hydrogen 2.838 N/A ARG 252.A NH2 GLU 16.A OE1 no hydrogen 2.864 N/A ILE 254.A N THR 281.A O no hydrogen 3.012 N/A ALA 255.A N ASP 296.A O no hydrogen 2.713 N/A VAL 256.A N ASP 284.A O no hydrogen 2.957 N/A GLY 259.A N ASP 257.A OD1 no hydrogen 3.193 N/A TYR 260.A N ASP 257.A O no hydrogen 2.916 N/A HIS 261.A N ASP 257.A O no hydrogen 2.886 N/A HIS 261.A ND1 TYR 267.A OH no hydrogen 2.762 N/A HIS 261.A NE2 GLU 292.A O no hydrogen 2.697 N/A GLY 264.A N ALA 282.A O no hydrogen 2.701 N/A TYR 267.A N VAL 280.A O no hydrogen 2.780 N/A TYR 267.A OH HIS 261.A ND1 no hydrogen 2.762 N/A TRP 268.A N TYR 319.A O no hydrogen 2.930 N/A LEU 269.A N ARG 278.A O no hydrogen 2.894 N/A ASP 270.A N ARG 317.A O no hydrogen 2.965 N/A ALA 271.A N TYR 276.A O no hydrogen 2.882 N/A ALA 272.A N THR 315.A O no hydrogen 3.228 N/A TYR 276.A N ALA 271.A O no hydrogen 3.251 N/A ARG 277.A NE ASP 270.A OD1 no hydrogen 2.889 N/A ARG 278.A N LEU 269.A O no hydrogen 3.337 N/A ARG 278.A NH1 GLY 251.A O no hydrogen 2.843 N/A ALA 279.A N GLU 16.A OE2 no hydrogen 2.870 N/A VAL 280.A N TYR 267.A O no hydrogen 2.787 N/A THR 281.A N ARG 252.A O no hydrogen 3.053 N/A THR 281.A OG1 GLY 265.A O no hydrogen 3.524 N/A ALA 282.A N GLY 265.A O no hydrogen 2.989 N/A LEU 283.A N ILE 254.A O no hydrogen 3.117 N/A THR 285.A OG1 VAL 256.A O no hydrogen 2.780 N/A THR 285.A OG1 GLY 286.A O no hydrogen 3.261 N/A GLY 286.A N THR 285.A OG1 no hydrogen 2.518 N/A ILE 289.A N GLY 286.A O no hydrogen 3.287 N/A GLY 291.A N ASP 257.A OD2 no hydrogen 2.927 N/A ARG 294.A NH1 LEU 75.A O no hydrogen 2.940 N/A ARG 294.A NH1 THR 77.A OG1 no hydrogen 3.230 N/A ARG 294.A NH2 THR 77.A OG1 no hydrogen 3.070 N/A ALA 295.A N LEU 75.A O no hydrogen 3.300 N/A ASP 296.A N ALA 255.A O no hydrogen 3.016 N/A LEU 297.A N THR 77.A O no hydrogen 2.807 N/A TYR 298.A N ALA 253.A O no hydrogen 2.706 N/A TYR 298.A OH GLU 239.A OE1 no hydrogen 2.596 N/A MET 299.A N TYR 79.A O no hydrogen 2.729 N/A SER 301.A OG GLU 239.A OE1 no hydrogen 3.332 N/A SER 301.A OG GLU 239.A OE2 no hydrogen 3.524 N/A GLY 306.A N GLY 302.A O no hydrogen 3.366 N/A VAL 307.A N ALA 303.A O no hydrogen 3.258 N/A GLU 308.A N VAL 304.A O no hydrogen 2.952 N/A ALA 309.A N ALA 305.A O no hydrogen 3.069 N/A ARG 311.A N GLU 308.A O no hydrogen 2.985 N/A VAL 312.A N ALA 309.A O no hydrogen 3.282 N/A ARG 313.A N HIS 314.A ND1 no hydrogen 2.979 N/A HIS 314.A N LEU 76.A O no hydrogen 2.758 N/A HIS 314.A NE2 PRO 274.A O no hydrogen 3.278 N/A LEU 316.A N GLY 74.A O no hydrogen 3.039 N/A ARG 317.A N ASP 270.A O no hydrogen 3.003 N/A ARG 317.A NH1 MET 1.A O no hydrogen 3.237 N/A ARG 317.A NH2 MET 1.A O no hydrogen 3.174 N/A TYR 319.A N TRP 268.A O no hydrogen 3.201 N/A ARG 320.A N GLU 66.A O no hydrogen 2.833 N/A LEU 321.A N PHE 266.A O no hydrogen 2.776 N/A THR 322.A N ARG 64.A O no hydrogen 2.874 N/A ASN 324.A N ASN 62.A O no hydrogen 2.796 N/A ASN 324.A ND2 ALA 61.A O no hydrogen 3.174 N/A