Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3d2e_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 2.A N TYR 131.A OH no hydrogen 3.376 N/A ILE 4.A N ASN 135.A O no hydrogen 2.930 N/A GLY 5.A N GLY 16.A O no hydrogen 2.975 N/A ILE 6.A N VAL 137.A O no hydrogen 2.881 N/A ASP 7.A N CYS 14.A O no hydrogen 2.961 N/A GLY 9.A N SER 13.A OG no hydrogen 3.209 N/A THR 10.A OG1 ASP 66.A OD1 no hydrogen 3.083 N/A SER 13.A N THR 35.A O no hydrogen 2.631 N/A SER 13.A OG ASP 7.A O no hydrogen 3.296 N/A SER 13.A OG SER 37.A OG no hydrogen 3.095 N/A CYS 14.A N ASP 7.A O no hydrogen 3.055 N/A CYS 14.A SG ARG 33.A O no hydrogen 3.364 N/A GLY 16.A N GLY 5.A O no hydrogen 2.879 N/A VAL 17.A N GLU 24.A O no hydrogen 2.890 N/A GLN 19.A N LYS 22.A O no hydrogen 2.766 N/A GLN 19.A NE2 TYR 128.A OH no hydrogen 2.465 N/A LYS 22.A N GLN 19.A O no hydrogen 3.360 N/A GLU 24.A N VAL 17.A O no hydrogen 2.789 N/A ILE 26.A N VAL 15.A O no hydrogen 3.038 N/A ASN 28.A N ASN 32.A O no hydrogen 2.761 N/A ASN 28.A ND2 THR 35.A OG1 no hydrogen 3.138 N/A ASN 28.A ND2 ASP 50.A OD2 no hydrogen 2.860 N/A GLN 30.A N ASN 28.A OD1 no hydrogen 2.890 N/A GLN 30.A NE2 ASP 29.A OD1 no hydrogen 3.184 N/A GLY 31.A N ASN 28.A O no hydrogen 2.816 N/A ASN 32.A N ASN 28.A OD1 no hydrogen 2.942 N/A ASN 32.A ND2 ASP 50.A OD2 no hydrogen 3.031 N/A ARG 33.A NE GLU 361.A OE2 no hydrogen 2.795 N/A ARG 33.A NH2 GLU 361.A OE1 no hydrogen 2.899 N/A THR 35.A N SER 13.A O no hydrogen 2.833 N/A SER 37.A N THR 11.A O no hydrogen 2.882 N/A SER 37.A OG GLY 9.A O no hydrogen 2.826 N/A SER 37.A OG SER 13.A OG no hydrogen 3.095 N/A VAL 39.A N VAL 64.A O no hydrogen 2.859 N/A ALA 40.A N LEU 47.A O no hydrogen 2.783 N/A PHE 41.A N ASN 62.A O no hydrogen 2.866 N/A THR 42.A N GLU 45.A O no hydrogen 3.012 N/A THR 42.A OG1 GLU 45.A O no hydrogen 3.373 N/A THR 44.A N THR 42.A OG1 no hydrogen 3.294 N/A THR 44.A OG1 GLU 45.A OE2 no hydrogen 3.514 N/A GLU 45.A N THR 42.A OG1 no hydrogen 3.191 N/A LEU 47.A N ALA 40.A O no hydrogen 2.961 N/A GLY 49.A N TYR 38.A O no hydrogen 3.065 N/A LYS 53.A N GLY 49.A O no hydrogen 3.005 N/A ASN 54.A N ASP 50.A O no hydrogen 2.770 N/A GLN 55.A N ALA 52.A O no hydrogen 3.387 N/A GLN 55.A NE2 ALA 52.A O no hydrogen 2.787 N/A GLN 55.A NE2 THR 63.A OG1 no hydrogen 2.996 N/A VAL 56.A N LYS 53.A O no hydrogen 3.339 N/A LEU 58.A N GLN 55.A O no hydrogen 3.219 N/A ASN 59.A N VAL 56.A O no hydrogen 3.097 N/A ASN 59.A ND2 PHE 41.A O no hydrogen 3.020 N/A ASN 59.A ND2 GLN 55.A OE1 no hydrogen 2.942 N/A ASN 62.A N ASN 59.A O no hydrogen 3.237 N/A ASN 62.A ND2 ASN 59.A OD1 no hydrogen 2.978 N/A THR 63.A OG1 ASN 59.A O no hydrogen 2.634 N/A VAL 64.A N VAL 39.A O no hydrogen 2.806 N/A LYS 68.A NZ LEU 8.A O no hydrogen 3.026 N/A LYS 68.A NZ GLU 169.A OE2 no hydrogen 2.669 N/A ARG 69.A N ASP 66.A O no hydrogen 2.837 N/A LEU 70.A N ALA 67.A O no hydrogen 2.868 N/A ILE 71.A N ALA 67.A O no hydrogen 2.959 N/A ARG 73.A N LEU 70.A O no hydrogen 3.302 N/A ARG 73.A NE ARG 69.A O no hydrogen 2.906 N/A ARG 73.A NH1 ASP 77.A OD2 no hydrogen 3.553 N/A PHE 75.A N ASP 95.A O no hydrogen 2.872 N/A GLY 76.A N ASP 95.A OD1 no hydrogen 3.279 N/A ASP 77.A N LYS 74.A O no hydrogen 2.986 N/A VAL 79.A N ASP 77.A OD1 no hydrogen 3.325 N/A GLN 81.A N ASP 77.A O no hydrogen 2.917 N/A SER 82.A N PRO 78.A O no hydrogen 2.928 N/A ASP 83.A N VAL 79.A O no hydrogen 2.880 N/A HIS 85.A N ASP 83.A O no hydrogen 2.948 N/A TRP 86.A NE1 ASP 66.A OD2 no hydrogen 2.793 N/A ILE 91.A N LYS 98.A O no hydrogen 2.812 N/A ASP 93.A N LYS 96.A O no hydrogen 2.985 N/A ASP 95.A N ASN 92.A OD1 no hydrogen 2.865 N/A LYS 96.A N ASP 93.A O no hydrogen 3.354 N/A LYS 98.A N ILE 91.A O no hydrogen 3.134 N/A LYS 98.A NZ ALA 109.A O no hydrogen 3.344 N/A VAL 99.A N PHE 110.A O no hydrogen 2.830 N/A GLN 100.A N GLN 89.A O no hydrogen 2.753 N/A GLN 100.A NE2 GLN 89.A OE1 no hydrogen 3.283 N/A VAL 101.A N LYS 108.A O no hydrogen 2.853 N/A SER 102.A N ASN 62.A OD1 no hydrogen 2.825 N/A TYR 103.A N GLU 106.A O no hydrogen 2.684 N/A LYS 104.A N THR 42.A O no hydrogen 2.897 N/A GLU 106.A N TYR 103.A O no hydrogen 3.075 N/A LYS 108.A N VAL 101.A O no hydrogen 2.739 N/A PHE 110.A N VAL 99.A O no hydrogen 2.801 N/A TYR 111.A N GLU 114.A OE2 no hydrogen 2.783 N/A GLU 113.A N GLU 113.A OE2 no hydrogen 2.716 N/A GLU 114.A N TYR 111.A O no hydrogen 2.925 N/A ILE 115.A N TYR 111.A O no hydrogen 3.194 N/A SER 116.A N PRO 112.A O no hydrogen 2.944 N/A SER 116.A OG PRO 112.A O no hydrogen 3.483 N/A SER 117.A N GLU 113.A O no hydrogen 2.975 N/A SER 117.A OG GLU 114.A O no hydrogen 2.759 N/A LEU 119.A N SER 116.A O no hydrogen 2.890 N/A THR 120.A N SER 117.A O no hydrogen 2.706 N/A THR 120.A OG1 SER 117.A O no hydrogen 2.847 N/A LYS 122.A NZ GLU 126.A OE2 no hydrogen 2.796 N/A LYS 122.A NZ VAL 133.A O no hydrogen 2.730 N/A GLU 123.A N THR 120.A O no hydrogen 2.888 N/A ILE 124.A N LYS 121.A O no hydrogen 2.955 N/A GLU 126.A N LYS 122.A O no hydrogen 2.866 N/A ALA 127.A N GLU 123.A O no hydrogen 2.965 N/A TYR 128.A N ILE 124.A O no hydrogen 3.183 N/A LEU 129.A N ALA 125.A O no hydrogen 2.999 N/A GLY 130.A N GLU 126.A O no hydrogen 2.927 N/A VAL 133.A N GLU 126.A OE2 no hydrogen 3.007 N/A ALA 136.A N ASN 162.A O no hydrogen 3.006 N/A VAL 137.A N ILE 4.A O no hydrogen 2.819 N/A ILE 138.A N ARG 165.A O no hydrogen 3.228 N/A THR 139.A N ILE 6.A O no hydrogen 3.111 N/A THR 139.A OG1 ILE 6.A O no hydrogen 3.474 N/A VAL 140.A N ILE 167.A O no hydrogen 2.887 N/A PHE 144.A N PRO 141.A O no hydrogen 3.123 N/A SER 147.A OG GLY 72.A O no hydrogen 2.861 N/A GLN 148.A N ASN 145.A OD1 no hydrogen 2.741 N/A ARG 149.A N ASN 145.A O no hydrogen 2.862 N/A ARG 149.A NE PHE 144.A O no hydrogen 2.994 N/A ARG 149.A NH1 ASN 168.A OD1 no hydrogen 2.832 N/A ARG 149.A NH2 PHE 144.A O no hydrogen 3.358 N/A ARG 149.A NH2 ASN 168.A OD1 no hydrogen 2.761 N/A GLN 150.A N ASP 146.A O no hydrogen 2.663 N/A ALA 151.A N SER 147.A O no hydrogen 2.859 N/A THR 152.A N GLN 148.A O no hydrogen 3.187 N/A THR 152.A OG1 GLN 148.A O no hydrogen 2.967 N/A LYS 153.A N ARG 149.A O no hydrogen 3.075 N/A ASP 154.A N GLN 150.A O no hydrogen 2.865 N/A ALA 155.A N ALA 151.A O no hydrogen 3.067 N/A GLY 156.A N THR 152.A O no hydrogen 3.084 N/A VAL 157.A N LYS 153.A O no hydrogen 2.881 N/A ILE 158.A N ASP 154.A O no hydrogen 2.820 N/A ALA 159.A N ALA 155.A O no hydrogen 2.996 N/A GLY 160.A N VAL 157.A O no hydrogen 3.101 N/A LEU 161.A N GLY 156.A O no hydrogen 3.018 N/A ASN 162.A N THR 134.A O no hydrogen 2.717 N/A ASN 162.A ND2 ASN 135.A OD1 no hydrogen 2.947 N/A LEU 164.A N ALA 136.A O no hydrogen 2.719 N/A ILE 167.A N ILE 138.A O no hydrogen 3.050 N/A GLU 169.A N VAL 140.A O no hydrogen 2.706 N/A ALA 172.A N ASN 168.A O no hydrogen 2.999 N/A ALA 173.A N GLU 169.A O no hydrogen 3.013 N/A ALA 174.A N PRO 170.A O no hydrogen 3.066 N/A ILE 175.A N THR 171.A O no hydrogen 2.882 N/A ALA 176.A N ALA 172.A O no hydrogen 2.910 N/A TYR 177.A N ALA 173.A O no hydrogen 3.427 N/A GLY 178.A N ILE 175.A O no hydrogen 3.134 N/A LEU 179.A N ALA 174.A O no hydrogen 3.082 N/A ASP 180.A N ASP 180.A OD1 no hydrogen 2.656 N/A ARG 181.A N GLY 178.A O no hydrogen 3.220 N/A GLY 185.A N ASP 207.A OD1 no hydrogen 2.566 N/A ARG 187.A N ILE 206.A O no hydrogen 2.821 N/A ARG 187.A NE ASP 327.A OD1 no hydrogen 3.087 N/A ARG 187.A NH2 ASP 327.A OD1 no hydrogen 3.292 N/A ARG 187.A NH2 ASP 327.A OD2 no hydrogen 2.720 N/A ASN 188.A ND2 GLN 324.A O no hydrogen 2.890 N/A VAL 189.A N LEU 204.A O no hydrogen 2.953 N/A LEU 190.A N ASP 327.A O no hydrogen 2.935 N/A ILE 191.A N SER 202.A O no hydrogen 2.774 N/A PHE 192.A N VAL 329.A O no hydrogen 2.840 N/A ASP 193.A N ASP 200.A O no hydrogen 2.952 N/A LEU 194.A N VAL 331.A O no hydrogen 3.055 N/A GLY 195.A N THR 198.A O no hydrogen 3.181 N/A THR 198.A OG1 GLY 195.A O no hydrogen 3.134 N/A ASP 200.A N ASP 193.A O no hydrogen 2.882 N/A VAL 201.A N ALA 217.A O no hydrogen 2.846 N/A SER 202.A N ILE 191.A O no hydrogen 3.016 N/A ILE 203.A N ALA 215.A O no hydrogen 2.832 N/A LEU 204.A N VAL 189.A O no hydrogen 2.890 N/A THR 205.A N GLU 212.A O no hydrogen 2.815 N/A THR 205.A OG1 ASN 188.A OD1 no hydrogen 3.018 N/A ILE 206.A N ARG 187.A O no hydrogen 2.883 N/A ASP 207.A N ILE 210.A O no hydrogen 3.090 N/A ASP 208.A N GLY 183.A O no hydrogen 3.061 N/A ILE 210.A N ASP 207.A O no hydrogen 3.053 N/A GLU 212.A N THR 205.A O no hydrogen 2.791 N/A LYS 214.A N ILE 203.A O no hydrogen 2.777 N/A LYS 214.A NZ GLU 212.A OE1 no hydrogen 3.377 N/A ALA 215.A N ILE 203.A O no hydrogen 3.189 N/A ALA 217.A N VAL 201.A O no hydrogen 2.713 N/A THR 220.A OG1 GLY 218.A O no hydrogen 3.192 N/A ASN 229.A N GLU 225.A O no hydrogen 2.998 N/A ARG 230.A N ASP 226.A O no hydrogen 3.250 N/A ARG 230.A NH1 LEU 299.A O no hydrogen 2.745 N/A ARG 230.A NH1 ASP 302.A OD1 no hydrogen 2.708 N/A ARG 230.A NH2 ASP 302.A OD1 no hydrogen 3.331 N/A ARG 230.A NH2 ASP 302.A OD2 no hydrogen 2.994 N/A LEU 231.A N PHE 227.A O no hydrogen 3.221 N/A VAL 232.A N ASP 228.A O no hydrogen 2.900 N/A ASN 233.A N ASN 229.A O no hydrogen 2.830 N/A HIS 234.A N ARG 230.A O no hydrogen 2.937 N/A PHE 235.A N LEU 231.A O no hydrogen 3.090 N/A VAL 236.A N VAL 232.A O no hydrogen 2.786 N/A GLU 237.A N ASN 233.A O no hydrogen 3.098 N/A GLU 238.A N HIS 234.A O no hydrogen 3.177 N/A PHE 239.A N PHE 235.A O no hydrogen 3.118 N/A LYS 240.A N VAL 236.A O no hydrogen 3.118 N/A ARG 241.A N GLU 237.A O no hydrogen 2.734 N/A LYS 242.A N GLU 238.A O no hydrogen 2.800 N/A HIS 243.A N PHE 239.A O no hydrogen 3.095 N/A SER 248.A N ASP 246.A OD1 no hydrogen 3.189 N/A SER 248.A OG ASP 246.A OD1 no hydrogen 3.103 N/A ASN 250.A N ILE 247.A O no hydrogen 3.186 N/A VAL 254.A N ASN 250.A O no hydrogen 3.105 N/A ARG 255.A N LYS 251.A O no hydrogen 3.512 N/A ARG 255.A NH1 GLU 262.A OE1 no hydrogen 3.293 N/A ARG 256.A N ARG 252.A O no hydrogen 3.026 N/A LEU 257.A N ALA 253.A O no hydrogen 2.842 N/A ARG 258.A N VAL 254.A O no hydrogen 2.659 N/A THR 259.A N ARG 255.A O no hydrogen 2.967 N/A THR 259.A OG1 ARG 255.A O no hydrogen 3.042 N/A ALA 260.A N ARG 256.A O no hydrogen 3.120 N/A CYS 261.A N LEU 257.A O no hydrogen 3.009 N/A CYS 261.A SG LEU 257.A O no hydrogen 3.147 N/A GLU 262.A N ARG 258.A O no hydrogen 2.892 N/A ARG 263.A N THR 259.A O no hydrogen 3.196 N/A ALA 264.A N ALA 260.A O no hydrogen 2.977 N/A LYS 265.A N CYS 261.A O no hydrogen 2.889 N/A LYS 265.A NZ ASP 228.A OD2 no hydrogen 2.720 N/A ARG 266.A N GLU 262.A O no hydrogen 3.162 N/A THR 267.A N ARG 263.A O no hydrogen 3.065 N/A THR 267.A OG1 ARG 263.A O no hydrogen 3.168 N/A LEU 268.A N ALA 264.A O no hydrogen 3.108 N/A SER 269.A N ARG 266.A O no hydrogen 3.340 N/A SER 270.A N THR 267.A O no hydrogen 3.007 N/A SER 271.A N THR 267.A O no hydrogen 2.911 N/A GLN 273.A NE2 THR 272.A OG1 no hydrogen 2.775 N/A ALA 274.A N ILE 291.A O no hydrogen 2.838 N/A LEU 276.A N THR 289.A O no hydrogen 2.700 N/A ILE 278.A N PHE 287.A O no hydrogen 3.088 N/A SER 280.A N ASP 286.A OD1 no hydrogen 2.655 N/A ILE 285.A N PHE 282.A O no hydrogen 2.928 N/A PHE 287.A N ILE 278.A O no hydrogen 3.289 N/A TYR 288.A OH ASP 279.A OD1 no hydrogen 2.548 N/A THR 289.A N LEU 276.A O no hydrogen 2.810 N/A THR 289.A OG1 GLU 238.A OE1 no hydrogen 3.292 N/A THR 289.A OG1 GLU 238.A OE2 no hydrogen 3.277 N/A SER 290.A N THR 289.A OG1 no hydrogen 2.780 N/A ILE 291.A N ALA 274.A O no hydrogen 2.803 N/A ARG 293.A N THR 272.A O no hydrogen 2.732 N/A ARG 293.A NE LEU 268.A O no hydrogen 2.881 N/A ARG 293.A NH2 LEU 268.A O no hydrogen 3.178 N/A ARG 295.A N THR 292.A OG1 no hydrogen 3.131 N/A ARG 295.A NH1 ARG 295.A O no hydrogen 3.424 N/A PHE 296.A N THR 292.A O no hydrogen 3.048 N/A GLU 297.A N ARG 293.A O no hydrogen 2.967 N/A GLU 298.A N ALA 294.A O no hydrogen 3.036 N/A LEU 299.A N ARG 295.A O no hydrogen 2.974 N/A CYS 300.A N PHE 296.A O no hydrogen 3.285 N/A CYS 300.A N GLU 297.A O no hydrogen 3.333 N/A CYS 300.A SG PHE 296.A O no hydrogen 3.616 N/A SER 301.A N GLU 298.A O no hydrogen 3.224 N/A SER 301.A OG GLU 298.A O no hydrogen 3.366 N/A PHE 304.A N CYS 300.A O no hydrogen 2.864 N/A ARG 305.A N SER 301.A O no hydrogen 2.916 N/A SER 306.A N ASP 302.A O no hydrogen 3.186 N/A SER 306.A OG LEU 303.A O no hydrogen 3.218 N/A THR 307.A N PHE 304.A O no hydrogen 3.129 N/A THR 307.A OG1 PHE 304.A O no hydrogen 2.765 N/A LEU 308.A N ARG 305.A O no hydrogen 3.035 N/A GLU 309.A N SER 306.A O no hydrogen 3.340 N/A GLU 312.A N LEU 308.A O no hydrogen 2.934 N/A LYS 313.A N GLU 309.A O no hydrogen 2.808 N/A ALA 314.A N PRO 310.A O no hydrogen 2.884 N/A LEU 315.A N VAL 311.A O no hydrogen 3.069 N/A ARG 316.A N GLU 312.A O no hydrogen 3.282 N/A ASP 317.A N LYS 313.A O no hydrogen 3.052 N/A ALA 318.A N ALA 314.A O no hydrogen 2.940 N/A LYS 319.A N ARG 316.A O no hydrogen 2.907 N/A LEU 320.A N LEU 315.A O no hydrogen 2.822 N/A ASP 321.A N GLN 324.A OE1 no hydrogen 2.807 N/A LYS 322.A NZ PHE 347.A O no hydrogen 2.778 N/A GLN 324.A N ASP 321.A O no hydrogen 2.798 N/A ILE 325.A N LYS 322.A O no hydrogen 3.442 N/A HIS 326.A N ASN 188.A O no hydrogen 2.612 N/A ASP 327.A N ASN 188.A O no hydrogen 3.183 N/A VAL 329.A N LEU 190.A O no hydrogen 3.052 N/A LEU 330.A N ASN 354.A O no hydrogen 2.879 N/A VAL 331.A N PHE 192.A O no hydrogen 2.911 N/A GLY 332.A N PRO 359.A O no hydrogen 2.714 N/A SER 334.A N LEU 194.A O no hydrogen 2.989 N/A THR 335.A N GLY 332.A O no hydrogen 3.182 N/A THR 335.A OG1 GLY 332.A O no hydrogen 2.777 N/A ARG 336.A N GLY 333.A O no hydrogen 3.196 N/A ARG 336.A NH1 ASP 360.A OD2 no hydrogen 2.786 N/A ARG 336.A NH2 ASP 360.A OD2 no hydrogen 2.434 N/A ILE 337.A N SER 334.A O no hydrogen 3.070 N/A GLN 341.A N ILE 337.A O no hydrogen 3.335 N/A GLN 341.A NE2 THR 335.A O no hydrogen 2.732 N/A LYS 342.A N PRO 338.A O no hydrogen 2.785 N/A LYS 342.A NZ GLU 297.A OE2 no hydrogen 2.636 N/A LEU 343.A N LYS 339.A O no hydrogen 2.797 N/A LEU 344.A N VAL 340.A O no hydrogen 3.271 N/A GLN 345.A N GLN 341.A O no hydrogen 3.014 N/A GLN 345.A NE2 ARG 351.A O no hydrogen 3.008 N/A ASP 346.A N LYS 342.A O no hydrogen 2.752 N/A PHE 347.A N LEU 343.A O no hydrogen 2.810 N/A PHE 348.A N LEU 344.A O no hydrogen 2.904 N/A GLY 350.A N GLN 345.A O no hydrogen 2.809 N/A ARG 351.A N PHE 348.A O no hydrogen 3.392 N/A ARG 351.A NH1 LYS 322.A O no hydrogen 2.946 N/A ASN 354.A N LEU 328.A O no hydrogen 2.765 N/A ASN 354.A ND2 LEU 328.A O no hydrogen 2.686 N/A LYS 355.A NZ GLN 341.A OE1 no hydrogen 3.565 N/A ILE 357.A N TYR 177.A OH no hydrogen 2.891 N/A ASP 360.A N ASN 358.A OD1 no hydrogen 2.695 N/A GLU 361.A N ASN 358.A O no hydrogen 2.697 N/A ALA 362.A N ASN 358.A O no hydrogen 3.029 N/A TYR 365.A N GLU 361.A O no hydrogen 2.885 N/A GLY 366.A N ALA 362.A O no hydrogen 3.150 N/A ALA 367.A N VAL 363.A O no hydrogen 3.096 N/A ALA 368.A N ALA 364.A O no hydrogen 2.893 N/A VAL 369.A N TYR 365.A O no hydrogen 2.998 N/A GLN 370.A N GLY 366.A O no hydrogen 2.883 N/A ALA 371.A N ALA 367.A O no hydrogen 2.740 N/A ALA 372.A N ALA 368.A O no hydrogen 3.161 N/A ILE 373.A N VAL 369.A O no hydrogen 3.078 N/A LEU 374.A N GLN 370.A O no hydrogen 3.158 N/A