Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3d5h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 6.A N ILE 250.A O no hydrogen 2.885 N/A VAL 7.A N TYR 29.A O no hydrogen 3.056 N/A TYR 8.A N LEU 252.A O no hydrogen 3.422 N/A TYR 8.A OH ASP 121.A OD2 no hydrogen 2.547 N/A TRP 9.A N ILE 31.A O no hydrogen 3.030 N/A TRP 9.A NE1 ARG 16.A O no hydrogen 2.907 N/A GLY 10.A N GLU 15.A OE2 no hydrogen 3.311 N/A GLN 11.A NE2 TRP 9.A O no hydrogen 3.073 N/A ASN 12.A N GLU 15.A OE1 no hydrogen 3.200 N/A ASP 14.A N ASN 12.A OD1 no hydrogen 3.094 N/A GLU 15.A N ASN 12.A O no hydrogen 3.012 N/A ARG 16.A NE THR 21.A OG1 no hydrogen 3.142 N/A ARG 16.A NH2 TYR 27.A OH no hydrogen 2.892 N/A ARG 16.A NH2 SER 255.A OG no hydrogen 2.836 N/A GLU 19.A N GLN 59.A OE1 no hydrogen 2.775 N/A ALA 20.A N SER 17.A OG no hydrogen 3.189 N/A THR 21.A N SER 17.A O no hydrogen 2.882 N/A THR 21.A OG1 SER 17.A O no hydrogen 2.775 N/A THR 21.A OG1 SER 255.A OG no hydrogen 3.366 N/A CYS 22.A N LEU 18.A O no hydrogen 2.998 N/A CYS 22.A SG LEU 18.A O no hydrogen 3.480 N/A ASP 23.A N GLU 19.A O no hydrogen 2.960 N/A THR 24.A N THR 21.A O no hydrogen 3.265 N/A THR 24.A OG1 THR 21.A O no hydrogen 2.817 N/A GLY 25.A N CYS 22.A O no hydrogen 3.306 N/A ASN 26.A N THR 24.A OG1 no hydrogen 3.150 N/A TYR 27.A OH ASP 258.A OD2 no hydrogen 2.511 N/A ALA 28.A N ILE 5.A O no hydrogen 2.907 N/A TYR 29.A N ILE 5.A O no hydrogen 3.474 N/A VAL 30.A N LYS 69.A O no hydrogen 2.838 N/A ILE 31.A N VAL 7.A O no hydrogen 2.746 N/A ILE 32.A N LEU 71.A O no hydrogen 2.563 N/A GLY 33.A N TRP 9.A O no hydrogen 2.953 N/A PHE 34.A N ASP 47.A O no hydrogen 3.071 N/A LEU 35.A N SER 73.A O no hydrogen 3.017 N/A ASN 36.A ND2 LYS 78.A O no hydrogen 3.558 N/A THR 37.A N ALA 45.A O no hydrogen 3.404 N/A THR 37.A OG1 ASN 36.A OD1 no hydrogen 3.347 N/A GLY 40.A N ASP 88.A OD2 no hydrogen 3.103 N/A GLN 42.A N GLY 39.A O no hydrogen 3.121 N/A GLN 42.A NE2 GLY 39.A O no hydrogen 3.352 N/A GLN 42.A NE2 PRO 80.A O no hydrogen 2.820 N/A ALA 45.A N THR 37.A O no hydrogen 3.078 N/A ASP 47.A N PHE 34.A O no hydrogen 2.800 N/A SER 49.A N ASP 47.A OD1 no hydrogen 2.934 N/A SER 49.A OG GLY 10.A O no hydrogen 2.816 N/A HIS 51.A N ILE 48.A O no hydrogen 3.108 N/A HIS 51.A NE2 GLU 15.A OE1 no hydrogen 2.780 N/A GLY 55.A N SER 52.A OG no hydrogen 3.214 N/A LEU 56.A N PRO 53.A O no hydrogen 3.063 N/A GLU 57.A N SER 54.A O no hydrogen 3.213 N/A ILE 60.A N LEU 56.A O no hydrogen 2.884 N/A LYS 61.A N GLU 57.A O no hydrogen 3.176 N/A LYS 61.A NZ GLU 57.A OE2 no hydrogen 2.951 N/A HIS 62.A N PRO 58.A O no hydrogen 2.927 N/A HIS 62.A NE2 ASP 23.A OD1 no hydrogen 2.537 N/A CYS 63.A N GLN 59.A O no hydrogen 2.902 N/A CYS 63.A SG LEU 18.A O no hydrogen 3.678 N/A CYS 63.A SG GLN 59.A O no hydrogen 3.277 N/A GLN 64.A N ILE 60.A O no hydrogen 2.948 N/A GLN 64.A NE2 VAL 116.A O no hydrogen 2.855 N/A GLN 64.A NE2 ASP 118.A OD2 no hydrogen 2.990 N/A SER 65.A N LYS 61.A O no hydrogen 2.977 N/A SER 65.A OG HIS 62.A O no hydrogen 2.876 N/A LYS 66.A N CYS 63.A O no hydrogen 2.949 N/A LYS 66.A NZ ASP 23.A OD1 no hydrogen 3.127 N/A ASN 67.A N GLN 64.A O no hydrogen 3.039 N/A VAL 68.A N CYS 63.A O no hydrogen 3.083 N/A LYS 69.A N ALA 28.A O no hydrogen 3.122 N/A VAL 70.A N ASP 118.A OD2 no hydrogen 2.842 N/A LEU 71.A N VAL 30.A O no hydrogen 2.944 N/A LEU 72.A N GLY 119.A O no hydrogen 3.098 N/A SER 73.A N ILE 32.A O no hydrogen 2.907 N/A SER 73.A OG ASP 121.A O no hydrogen 3.440 N/A SER 73.A OG ASP 121.A OD2 no hydrogen 2.805 N/A ILE 74.A N ASP 121.A O no hydrogen 2.714 N/A GLY 75.A N LEU 35.A O no hydrogen 2.924 N/A GLY 76.A N HIS 123.A O no hydrogen 2.728 N/A TYR 81.A OH GLY 76.A O no hydrogen 2.622 N/A SER 82.A N PHE 38.A O no hydrogen 3.158 N/A SER 82.A OG ASP 84.A OD2 no hydrogen 3.519 N/A ASP 88.A N SER 85.A OG no hydrogen 2.990 N/A ALA 89.A N SER 85.A O no hydrogen 3.273 N/A ASN 90.A N ARG 86.A O no hydrogen 3.119 N/A ASP 91.A N SER 87.A O no hydrogen 2.879 N/A LEU 92.A N ASP 88.A O no hydrogen 2.938 N/A ALA 93.A N ALA 89.A O no hydrogen 2.952 N/A VAL 94.A N ASN 90.A O no hydrogen 3.069 N/A TYR 95.A N ASP 91.A O no hydrogen 3.022 N/A LEU 96.A N LEU 92.A O no hydrogen 2.941 N/A PHE 97.A N ALA 93.A O no hydrogen 2.990 N/A ASN 98.A N VAL 94.A O no hydrogen 3.020 N/A ASN 98.A ND2 VAL 94.A O no hydrogen 2.360 N/A ASN 99.A N TYR 95.A O no hydrogen 3.011 N/A ASN 99.A ND2 TYR 95.A O no hydrogen 3.168 N/A PHE 100.A N LEU 96.A O no hydrogen 2.959 N/A LEU 101.A N LEU 96.A O no hydrogen 3.305 N/A LEU 101.A N PHE 97.A O no hydrogen 3.241 N/A SER 107.A OG HIS 106.A O no hydrogen 2.668 N/A ARG 110.A NE GLY 113.A O no hydrogen 2.803 N/A ARG 110.A NH1 LEU 102.A O no hydrogen 3.157 N/A ARG 110.A NH2 LEU 102.A O no hydrogen 2.999 N/A ARG 110.A NH2 ALA 115.A O no hydrogen 2.843 N/A GLY 113.A N ARG 110.A O no hydrogen 3.042 N/A ASN 114.A N GLU 57.A OE2 no hydrogen 3.191 N/A LEU 117.A N PHE 100.A O no hydrogen 2.832 N/A ASP 118.A N VAL 70.A O no hydrogen 2.828 N/A ILE 120.A N ALA 150.A O no hydrogen 3.042 N/A ASP 121.A N LEU 72.A O no hydrogen 2.770 N/A PHE 122.A N THR 152.A O no hydrogen 2.852 N/A HIS 123.A N ILE 74.A O no hydrogen 2.962 N/A HIS 123.A ND1 TYR 8.A OH no hydrogen 2.961 N/A GLU 125.A N TYR 81.A OH no hydrogen 2.831 N/A HIS 126.A NE2 TYR 81.A O no hydrogen 2.784 N/A GLY 128.A N ASN 163.A OD1 no hydrogen 2.926 N/A GLN 131.A N LEU 83.A O no hydrogen 3.286 N/A TYR 132.A N PRO 129.A O no hydrogen 2.916 N/A LEU 135.A N GLN 131.A O no hydrogen 3.129 N/A ALA 136.A N TYR 132.A O no hydrogen 2.927 N/A ASN 137.A N GLN 133.A O no hydrogen 2.847 N/A ILE 138.A N LEU 134.A O no hydrogen 2.996 N/A LEU 139.A N LEU 135.A O no hydrogen 3.004 N/A SER 140.A N ALA 136.A O no hydrogen 2.759 N/A SER 141.A N ASN 137.A O no hydrogen 3.093 N/A PHE 142.A N ILE 138.A O no hydrogen 3.149 N/A ARG 143.A N LEU 139.A O no hydrogen 3.130 N/A ARG 143.A NH1 THR 172.A O no hydrogen 3.416 N/A ARG 143.A NH2 SER 140.A OG no hydrogen 3.023 N/A ARG 143.A NH2 THR 172.A O no hydrogen 3.233 N/A LEU 144.A N SER 140.A O no hydrogen 3.047 N/A LEU 144.A N SER 141.A O no hydrogen 3.118 N/A ALA 145.A N PHE 142.A O no hydrogen 3.058 N/A THR 147.A OG1 PHE 142.A O no hydrogen 3.313 N/A ALA 150.A N ASP 118.A O no hydrogen 2.908 N/A LEU 151.A N ASP 174.A OD2 no hydrogen 2.836 N/A THR 152.A N ILE 120.A O no hydrogen 2.982 N/A THR 152.A OG1 ASP 121.A OD1 no hydrogen 2.833 N/A ALA 153.A N ALA 175.A O no hydrogen 3.333 N/A ALA 154.A N PHE 122.A O no hydrogen 2.992 N/A GLN 156.A N ASP 161.A OD2 no hydrogen 2.852 N/A ASN 163.A N ASP 161.A OD1 no hydrogen 2.986 N/A LEU 164.A N ASP 161.A OD1 no hydrogen 2.899 N/A GLY 165.A N ASP 161.A O no hydrogen 2.768 N/A ILE 168.A N LEU 164.A O no hydrogen 2.693 N/A ASN 169.A N GLY 165.A O no hydrogen 2.933 N/A SER 170.A N VAL 167.A O no hydrogen 3.124 N/A SER 170.A OG VAL 167.A O no hydrogen 2.832 N/A ALA 171.A N ILE 168.A O no hydrogen 3.060 N/A ASP 174.A N LEU 151.A O no hydrogen 2.843 N/A ILE 176.A N LYS 211.A O no hydrogen 3.007 N/A TRP 177.A N ALA 153.A O no hydrogen 2.947 N/A TRP 177.A NE1 ASP 121.A OD1 no hydrogen 2.950 N/A VAL 178.A N PHE 213.A O no hydrogen 3.086 N/A GLN 179.A N PRO 155.A O no hydrogen 2.975 N/A GLN 179.A NE2 GLU 125.A OE2 no hydrogen 3.316 N/A GLN 179.A NE2 ALA 154.A O no hydrogen 3.268 N/A PHE 180.A N GLY 215.A O no hydrogen 2.859 N/A TYR 181.A OH GLN 179.A OE1 no hydrogen 3.146 N/A ASN 182.A N SER 225.A O no hydrogen 3.059 N/A GLN 185.A N ASN 183.A OD1 no hydrogen 2.685 N/A CYS 186.A N ASN 183.A O no hydrogen 3.028 N/A CYS 186.A SG ASN 183.A O no hydrogen 4.028 N/A SER 187.A OG ASN 183.A O no hydrogen 2.643 N/A GLU 194.A N ASN 192.A OD1 no hydrogen 3.441 N/A MET 197.A N ALA 193.A O no hydrogen 2.757 N/A ASN 198.A N GLU 194.A O no hydrogen 2.921 N/A ALA 199.A N ALA 195.A O no hydrogen 3.211 N/A TRP 200.A N LEU 196.A O no hydrogen 2.917 N/A ARG 201.A N MET 197.A O no hydrogen 2.994 N/A ARG 201.A NH1 ASN 198.A OD1 no hydrogen 3.211 N/A GLU 202.A N ASN 198.A O no hydrogen 3.219 N/A TRP 203.A N ALA 199.A O no hydrogen 2.896 N/A TRP 203.A NE1 CYS 157.A O no hydrogen 2.892 N/A SER 204.A N TRP 200.A O no hydrogen 2.806 N/A SER 204.A OG TRP 200.A O no hydrogen 3.111 N/A SER 204.A OG ARG 201.A O no hydrogen 3.440 N/A MET 205.A N ARG 201.A O no hydrogen 3.105 N/A LYS 206.A N GLU 202.A O no hydrogen 2.869 N/A ALA 207.A N TRP 203.A O no hydrogen 3.018 N/A ARG 208.A NH1 ASN 169.A O no hydrogen 2.928 N/A THR 209.A N ALA 207.A O no hydrogen 2.991 N/A THR 209.A OG1 PHE 173.A O no hydrogen 2.789 N/A LYS 211.A NZ LYS 210.A O no hydrogen 3.274 N/A LYS 211.A NZ TYR 245.A O no hydrogen 3.430 N/A VAL 212.A N LYS 246.A O no hydrogen 2.749 N/A PHE 213.A N ILE 176.A O no hydrogen 2.796 N/A LEU 214.A N GLY 249.A O no hydrogen 3.071 N/A GLY 215.A N VAL 178.A O no hydrogen 2.836 N/A PHE 216.A N MET 251.A O no hydrogen 2.944 N/A ALA 218.A N TRP 253.A O no hydrogen 2.764 N/A ASP 221.A N HIS 219.A ND1 no hydrogen 2.825 N/A ALA 222.A N HIS 219.A O no hydrogen 2.884 N/A GLY 224.A N ASN 182.A OD1 no hydrogen 2.687 N/A LYS 232.A N PRO 229.A O no hydrogen 3.061 N/A LYS 232.A NZ TYR 188.A OH no hydrogen 2.840 N/A VAL 233.A N PRO 229.A O no hydrogen 3.092 N/A LYS 234.A N PRO 230.A O no hydrogen 2.987 N/A LYS 234.A NZ LYS 266.A O no hydrogen 3.106 N/A PHE 235.A N GLU 231.A O no hydrogen 3.066 N/A HIS 236.A N LYS 232.A O no hydrogen 2.853 N/A VAL 237.A N VAL 233.A O no hydrogen 3.117 N/A PHE 238.A N VAL 233.A O no hydrogen 3.224 N/A ALA 241.A N VAL 237.A O no hydrogen 2.851 N/A LYS 242.A N PHE 238.A O no hydrogen 2.825 N/A LYS 243.A N ALA 240.A O no hydrogen 3.107 N/A SER 244.A N ALA 241.A O no hydrogen 3.029 N/A LYS 246.A N SER 244.A OG no hydrogen 2.993 N/A LYS 246.A NZ SER 204.A O no hydrogen 3.034 N/A LYS 246.A NZ MET 205.A O no hydrogen 3.382 N/A LYS 246.A NZ ALA 207.A O no hydrogen 2.714 N/A PHE 247.A N SER 244.A O no hydrogen 3.126 N/A GLY 248.A N VAL 212.A O no hydrogen 2.852 N/A ILE 250.A N ASP 4.A O no hydrogen 3.255 N/A MET 251.A N LEU 214.A O no hydrogen 2.824 N/A LEU 252.A N ALA 6.A O no hydrogen 2.830 N/A TRP 253.A N PHE 216.A O no hydrogen 3.033 N/A SER 255.A N TYR 8.A O no hydrogen 2.824 N/A SER 255.A OG THR 21.A OG1 no hydrogen 3.366 N/A TRP 257.A N ASP 254.A OD1 no hydrogen 3.189 N/A ASP 258.A N ASP 254.A O no hydrogen 2.949 N/A THR 259.A N SER 255.A O no hydrogen 3.020 N/A THR 259.A OG1 SER 255.A O no hydrogen 2.970 N/A VAL 260.A N TRP 257.A O no hydrogen 3.181 N/A SER 261.A N TRP 257.A O no hydrogen 2.917 N/A SER 261.A OG ALA 218.A O no hydrogen 2.685 N/A SER 261.A OG TRP 257.A O no hydrogen 3.300 N/A ASN 262.A N ASP 258.A O no hydrogen 2.764 N/A PHE 263.A N SER 261.A OG no hydrogen 3.114 N/A SER 264.A N ASP 258.A OD1 no hydrogen 2.909 N/A SER 264.A OG ASN 26.A OD1 no hydrogen 2.926 N/A SER 264.A OG ASP 258.A OD1 no hydrogen 3.547 N/A SER 264.A OG ASP 258.A OD2 no hydrogen 2.681 N/A LYS 266.A N ASN 262.A O no hydrogen 3.051 N/A LYS 266.A NZ SER 261.A O no hydrogen 3.144 N/A ILE 267.A N PHE 263.A O no hydrogen 3.104 N/A TRP 272.A N GLU 270.A O no hydrogen 3.095 N/A