Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3dg8_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 3.A N ASP 1.A OD1 no hydrogen 3.003 N/A ASP 6.A N GLU 3.A O no hydrogen 2.961 N/A PHE 8.A N GLU 4.A O no hydrogen 3.261 N/A VAL 9.A N ASP 6.A O no hydrogen 3.080 N/A PHE 11.A N ASP 7.A O no hydrogen 3.101 N/A ASN 12.A N VAL 9.A O no hydrogen 3.287 N/A ASN 12.A ND2 PHE 8.A O no hydrogen 2.874 N/A PHE 13.A N TYR 10.A O no hydrogen 3.025 N/A GLU 16.A N GLU 16.A OE1 no hydrogen 2.564 N/A LYS 20.A N LYS 17.A O no hydrogen 2.985 N/A ASN 21.A ND2 ASN 56.A OD1 no hydrogen 2.656 N/A LYS 22.A NZ GLY 57.A O no hydrogen 3.399 N/A LYS 22.A NZ ASN 58.A OD1 no hydrogen 2.629 N/A ASN 23.A N MET 55.A O no hydrogen 3.327 N/A ASN 23.A ND2 MET 54.A O no hydrogen 2.861 N/A ASN 23.A ND2 GLY 57.A O no hydrogen 3.323 N/A HIS 26.A N SER 24.A O no hydrogen 2.188 N/A TYR 33.A N ASN 283.A OD1 no hydrogen 3.305 N/A TYR 33.A OH ASN 48.A OD1 no hydrogen 2.647 N/A ASN 34.A N PHE 30.A O no hydrogen 2.966 N/A SER 35.A N GLN 31.A O no hydrogen 3.164 N/A SER 35.A N ILE 32.A O no hydrogen 2.960 N/A SER 35.A OG ILE 32.A O no hydrogen 2.642 N/A LEU 36.A N ILE 32.A O no hydrogen 3.190 N/A HIS 41.A NE2 TYR 287.A O no hydrogen 2.818 N/A GLU 43.A N HIS 41.A ND1 no hydrogen 2.895 N/A TYR 44.A N HIS 41.A O no hydrogen 2.916 N/A GLN 45.A N PRO 42.A O no hydrogen 2.951 N/A GLN 45.A NE2 LYS 77.A O no hydrogen 2.467 N/A TYR 46.A N GLU 43.A O no hydrogen 2.995 N/A TYR 46.A OH LEU 232.A O no hydrogen 2.481 N/A LEU 47.A N GLU 43.A O no hydrogen 3.060 N/A ASN 48.A N TYR 44.A O no hydrogen 2.626 N/A ILE 50.A N TYR 46.A O no hydrogen 3.107 N/A TYR 51.A N LEU 47.A O no hydrogen 3.020 N/A ASP 52.A N ASN 48.A O no hydrogen 2.889 N/A ILE 53.A N ILE 49.A O no hydrogen 2.864 N/A MET 54.A N ILE 50.A O no hydrogen 3.060 N/A MET 55.A N TYR 51.A O no hydrogen 2.916 N/A ASN 56.A N ASP 52.A O no hydrogen 2.810 N/A ASN 56.A ND2 ASP 52.A O no hydrogen 3.455 N/A ASN 56.A ND2 ASP 52.A OD1 no hydrogen 2.767 N/A GLY 57.A N ILE 53.A O no hydrogen 2.531 N/A ASN 58.A N SER 70.A O no hydrogen 2.732 N/A GLN 60.A N VAL 68.A O no hydrogen 2.982 N/A ASP 62.A N VAL 66.A O no hydrogen 2.915 N/A VAL 68.A N GLN 60.A O no hydrogen 2.727 N/A LEU 69.A N VAL 270.A O no hydrogen 2.808 N/A SER 70.A N ASN 58.A O no hydrogen 2.815 N/A SER 70.A OG GLN 60.A OE1 no hydrogen 2.672 N/A LYS 71.A N ALA 268.A O no hydrogen 2.917 N/A GLY 73.A N GLY 266.A O no hydrogen 2.905 N/A TYR 74.A N LEU 265.A O no hydrogen 3.069 N/A TYR 74.A OH ASP 52.A OD2 no hydrogen 2.306 N/A MET 76.A N HIS 263.A O no hydrogen 2.833 N/A LYS 77.A N GLN 45.A OE1 no hydrogen 3.031 N/A PHE 78.A N PHE 261.A O no hydrogen 3.028 N/A ASP 79.A N TYR 83.A OH no hydrogen 2.987 N/A LEU 80.A N ALA 259.A O no hydrogen 2.817 N/A SER 81.A N ASP 79.A OD1 no hydrogen 2.939 N/A SER 81.A OG ASP 79.A OD1 no hydrogen 2.550 N/A GLN 82.A N ASP 79.A O no hydrogen 2.936 N/A TYR 83.A N ASP 79.A O no hydrogen 3.235 N/A PHE 84.A N PRO 290.A O no hydrogen 3.048 N/A LEU 86.A N PHE 84.A O no hydrogen 2.834 N/A THR 88.A N GLU 43.A OE1 no hydrogen 2.819 N/A THR 88.A N GLU 43.A OE2 no hydrogen 3.139 N/A THR 88.A OG1 GLU 43.A OE1 no hydrogen 2.960 N/A THR 89.A N GLU 43.A OE2 no hydrogen 2.857 N/A THR 89.A OG1 GLU 43.A OE2 no hydrogen 2.541 N/A LEU 92.A N TYR 314.A OH no hydrogen 3.115 N/A ARG 95.A NH1 LYS 117.A O no hydrogen 3.073 N/A ARG 95.A NH2 LYS 117.A O no hydrogen 3.137 N/A ARG 95.A NH2 ASN 118.A O no hydrogen 3.369 N/A ILE 98.A N LEU 94.A O no hydrogen 2.947 N/A GLU 99.A N ARG 95.A O no hydrogen 3.101 N/A GLU 100.A N GLY 96.A O no hydrogen 2.957 N/A LEU 101.A N ILE 97.A O no hydrogen 3.052 N/A LEU 102.A N ILE 98.A O no hydrogen 2.910 N/A TRP 103.A N GLU 99.A O no hydrogen 2.828 N/A TRP 103.A NE1 ASN 110.A O no hydrogen 3.093 N/A PHE 104.A N GLU 100.A O no hydrogen 2.829 N/A ILE 105.A N LEU 101.A O no hydrogen 2.938 N/A ARG 106.A N LEU 102.A O no hydrogen 2.948 N/A ARG 106.A NE GLU 108.A OE2 no hydrogen 2.585 N/A ARG 106.A NH2 GLU 108.A OE2 no hydrogen 2.768 N/A GLY 107.A N PHE 104.A O no hydrogen 2.624 N/A GLU 108.A N TRP 103.A O no hydrogen 3.177 N/A THR 109.A OG1 TYR 159.A OH no hydrogen 2.826 N/A GLY 111.A N ASN 142.A O no hydrogen 2.834 N/A ASN 112.A N ASN 110.A OD1 no hydrogen 2.792 N/A THR 113.A N ASN 110.A O no hydrogen 3.153 N/A THR 113.A OG1 GLU 108.A OE1 no hydrogen 2.536 N/A THR 113.A OG1 ASN 110.A O no hydrogen 3.410 N/A LEU 115.A N GLY 111.A O no hydrogen 3.105 N/A ASN 116.A N ASN 112.A O no hydrogen 2.871 N/A LYS 117.A N LEU 114.A O no hydrogen 2.858 N/A ASN 118.A N LEU 115.A O no hydrogen 3.014 N/A VAL 119.A N LEU 114.A O no hydrogen 2.920 N/A ARG 120.A NH1 GLU 123.A OE1 no hydrogen 3.337 N/A TRP 122.A NE1 GLU 100.A OE2 no hydrogen 2.722 N/A GLU 123.A N ARG 120.A O no hydrogen 3.026 N/A ASN 125.A N TRP 122.A O no hydrogen 3.192 N/A GLY 126.A N GLU 123.A O no hydrogen 3.042 N/A THR 127.A OG1 GLU 129.A OE1 no hydrogen 3.304 N/A ARG 128.A NE ASP 132.A OD1 no hydrogen 3.131 N/A ARG 128.A NE ASP 132.A OD2 no hydrogen 3.094 N/A ARG 128.A NH1 ARG 139.A O no hydrogen 3.033 N/A ARG 128.A NH2 ASP 132.A OD1 no hydrogen 3.071 N/A ARG 128.A NH2 ARG 139.A O no hydrogen 3.004 N/A PHE 130.A N THR 127.A OG1 no hydrogen 2.925 N/A LEU 131.A N THR 127.A O no hydrogen 2.776 N/A ASP 132.A N ARG 128.A O no hydrogen 2.801 N/A ASN 133.A N GLU 129.A O no hydrogen 2.985 N/A ARG 134.A N PHE 130.A O no hydrogen 3.151 N/A ARG 134.A N LEU 131.A O no hydrogen 3.006 N/A ARG 134.A NE MET 203.A O no hydrogen 3.086 N/A ARG 134.A NH2 MET 203.A O no hydrogen 2.813 N/A LYS 135.A N ASP 132.A O no hydrogen 2.967 N/A LEU 136.A N LEU 131.A O no hydrogen 2.838 N/A ARG 139.A N LEU 136.A O no hydrogen 3.157 N/A ARG 139.A NH1 ASP 143.A O no hydrogen 3.355 N/A ARG 139.A NH1 GLN 202.A O no hydrogen 3.048 N/A ARG 139.A NH2 GLN 202.A O no hydrogen 2.957 N/A ASN 142.A N GLY 126.A O no hydrogen 2.688 N/A ASP 143.A N GLU 140.A O no hydrogen 2.873 N/A LEU 144.A N THR 109.A O no hydrogen 3.217 N/A GLY 145.A N ASP 143.A OD1 no hydrogen 3.036 N/A ILE 147.A N GLY 145.A O no hydrogen 2.829 N/A GLN 151.A N ILE 147.A O no hydrogen 3.034 N/A GLN 151.A NE2 PRO 146.A O no hydrogen 3.042 N/A GLN 151.A NE2 ASP 199.A OD2 no hydrogen 2.822 N/A TRP 152.A N TYR 148.A O no hydrogen 2.754 N/A ARG 153.A N GLY 149.A O no hydrogen 3.241 N/A ARG 153.A NE ASP 172.A OD1 no hydrogen 2.688 N/A ARG 153.A NE ASP 172.A OD2 no hydrogen 3.276 N/A ARG 153.A NH1 ILE 105.A O no hydrogen 2.917 N/A ARG 153.A NH1 GLU 302.A OE2 no hydrogen 3.177 N/A ARG 153.A NH2 ASP 172.A OD2 no hydrogen 2.760 N/A ARG 153.A NH2 GLU 302.A OE2 no hydrogen 3.227 N/A HIS 154.A N PHE 150.A O no hydrogen 2.646 N/A HIS 154.A ND1 LYS 169.A O no hydrogen 2.961 N/A PHE 155.A N VAL 171.A O no hydrogen 3.192 N/A ALA 157.A N HIS 154.A O no hydrogen 3.084 N/A TYR 159.A OH THR 109.A OG1 no hydrogen 2.826 N/A TYR 159.A OH ASP 143.A OD1 no hydrogen 2.687 N/A THR 160.A N TYR 166.A OH no hydrogen 2.897 N/A THR 160.A OG1 ASP 164.A OD2 no hydrogen 2.647 N/A THR 160.A OG1 TYR 166.A OH no hydrogen 2.873 N/A ASN 161.A N THR 160.A OG1 no hydrogen 2.575 N/A MET 162.A N ASP 143.A OD2 no hydrogen 2.777 N/A TYR 163.A N ASN 161.A OD1 no hydrogen 2.849 N/A ASP 164.A N ASN 161.A O no hydrogen 3.163 N/A TYR 166.A OH THR 160.A OG1 no hydrogen 2.873 N/A TYR 166.A OH ASN 161.A O no hydrogen 2.784 N/A GLU 167.A N ASN 165.A OD1 no hydrogen 3.009 N/A LYS 169.A N TYR 166.A O no hydrogen 3.018 N/A VAL 171.A N PHE 155.A O no hydrogen 2.714 N/A GLN 173.A NE2 GLN 151.A O no hydrogen 2.624 N/A GLN 173.A NE2 CYS 193.A O no hydrogen 3.055 N/A LEU 174.A N TRP 152.A O no hydrogen 3.160 N/A LYS 175.A N ASP 172.A OD1 no hydrogen 3.146 N/A LYS 175.A NZ GLU 302.A OE1 no hydrogen 2.775 N/A ASN 176.A N ASP 172.A O no hydrogen 3.135 N/A ILE 177.A N GLN 173.A O no hydrogen 2.840 N/A ILE 178.A N LEU 174.A O no hydrogen 3.134 N/A ASN 179.A N LYS 175.A O no hydrogen 3.004 N/A LEU 180.A N ASN 176.A O no hydrogen 2.919 N/A ILE 181.A N ILE 177.A O no hydrogen 3.004 N/A LYS 182.A N ILE 178.A O no hydrogen 3.259 N/A ASN 183.A N ASN 179.A O no hydrogen 2.971 N/A ASP 184.A N LEU 180.A O no hydrogen 2.704 N/A SER 187.A N ASP 184.A O no hydrogen 2.946 N/A ARG 189.A N SER 187.A OG no hydrogen 3.140 N/A LEU 191.A N ARG 189.A O no hydrogen 2.920 N/A LEU 192.A N CYS 212.A O no hydrogen 2.832 N/A CYS 193.A N GLN 173.A OE1 no hydrogen 2.756 N/A CYS 193.A SG TRP 195.A O no hydrogen 3.884 N/A CYS 193.A SG ILE 210.A O no hydrogen 3.965 N/A ALA 194.A N ILE 210.A O no hydrogen 2.920 N/A ASN 196.A N ALA 194.A O no hydrogen 2.934 N/A ASN 196.A ND2 GLN 151.A OE1 no hydrogen 2.953 N/A LYS 198.A N ASN 196.A OD1 no hydrogen 3.008 N/A ASP 199.A N ASN 196.A O no hydrogen 2.850 N/A ASP 199.A N ASN 196.A OD1 no hydrogen 3.315 N/A GLN 202.A N ASP 199.A O no hydrogen 2.875 N/A MET 203.A N LEU 200.A O no hydrogen 3.183 N/A ALA 204.A N LEU 144.A O no hydrogen 3.027 N/A CYS 208.A N TYR 148.A OH no hydrogen 2.923 N/A HIS 209.A N TYR 148.A OH no hydrogen 3.182 N/A ILE 210.A N TYR 226.A O no hydrogen 2.940 N/A CYS 212.A N LEU 192.A O no hydrogen 2.991 N/A GLN 213.A N ILE 224.A O no hydrogen 2.840 N/A PHE 214.A N ILE 190.A O no hydrogen 2.871 N/A TYR 215.A N SER 222.A O no hydrogen 3.074 N/A PHE 217.A N LYS 220.A O no hydrogen 2.979 N/A LYS 220.A N PHE 217.A O no hydrogen 2.764 N/A LEU 221.A N GLN 257.A O no hydrogen 2.780 N/A SER 222.A N TYR 215.A O no hydrogen 2.887 N/A CYS 223.A N GLN 260.A O no hydrogen 2.803 N/A ILE 224.A N GLN 213.A O no hydrogen 2.877 N/A MET 225.A N ILE 262.A O no hydrogen 2.711 N/A TYR 226.A N LEU 211.A O no hydrogen 3.008 N/A GLN 227.A N VAL 264.A O no hydrogen 2.851 N/A GLN 227.A NE2 SER 229.A O no hydrogen 3.137 N/A GLN 227.A NE2 ASN 239.A OD1 no hydrogen 2.835 N/A ARG 228.A N CYS 208.A O no hydrogen 2.983 N/A ARG 228.A NE PRO 207.A O no hydrogen 2.753 N/A ARG 228.A NH2 PRO 206.A O no hydrogen 3.150 N/A CYS 230.A N ASN 267.A O no hydrogen 2.919 N/A CYS 230.A SG GLN 227.A O no hydrogen 3.636 N/A CYS 230.A SG ASN 267.A O no hydrogen 3.846 N/A LEU 232.A N HIS 269.A O no hydrogen 3.088 N/A GLY 235.A N ASP 231.A O no hydrogen 2.918 N/A GLY 235.A N ASP 231.A OD2 no hydrogen 3.359 N/A VAL 236.A N ASP 231.A O no hydrogen 3.119 N/A ASN 239.A N GLY 235.A O no hydrogen 2.894 N/A ILE 240.A N VAL 236.A O no hydrogen 2.859 N/A SER 242.A N PHE 238.A O no hydrogen 2.866 N/A SER 242.A OG PHE 238.A O no hydrogen 3.553 N/A TYR 243.A N ASN 239.A O no hydrogen 3.209 N/A TYR 243.A OH HIS 209.A ND1 no hydrogen 3.406 N/A SER 244.A N ILE 240.A O no hydrogen 3.169 N/A SER 244.A OG ILE 240.A O no hydrogen 2.606 N/A ILE 245.A N ALA 241.A O no hydrogen 2.876 N/A PHE 246.A N SER 242.A O no hydrogen 2.890 N/A THR 247.A N TYR 243.A O no hydrogen 2.901 N/A THR 247.A OG1 TYR 243.A O no hydrogen 3.000 N/A HIS 248.A N SER 244.A O no hydrogen 3.149 N/A MET 249.A N ILE 245.A O no hydrogen 2.994 N/A ILE 250.A N PHE 246.A O no hydrogen 2.883 N/A ALA 251.A N THR 247.A O no hydrogen 2.921 N/A GLN 252.A N HIS 248.A O no hydrogen 3.014 N/A GLN 252.A NE2 ASN 295.A O no hydrogen 2.948 N/A GLN 252.A NE2 ILE 298.A O no hydrogen 3.012 N/A VAL 253.A N MET 249.A O no hydrogen 3.146 N/A CYS 254.A N ALA 251.A O no hydrogen 3.066 N/A CYS 254.A SG ILE 178.A O no hydrogen 3.745 N/A CYS 254.A SG ILE 250.A O no hydrogen 3.252 N/A ASN 255.A N GLN 252.A O no hydrogen 2.936 N/A LEU 256.A N ALA 251.A O no hydrogen 2.889 N/A GLN 257.A N GLY 219.A O no hydrogen 2.951 N/A ALA 259.A N LEU 221.A O no hydrogen 2.709 N/A GLN 260.A N SER 222.A OG no hydrogen 3.057 N/A PHE 261.A N PHE 78.A O no hydrogen 2.972 N/A ILE 262.A N CYS 223.A O no hydrogen 2.531 N/A HIS 263.A N MET 76.A O no hydrogen 2.819 N/A HIS 263.A NE2 GLN 227.A OE1 no hydrogen 2.570 N/A VAL 264.A N MET 225.A O no hydrogen 2.871 N/A LEU 265.A N TYR 74.A O no hydrogen 2.778 N/A GLY 266.A N GLN 227.A O no hydrogen 2.703 N/A ASN 267.A N ARG 228.A O no hydrogen 2.952 N/A ALA 268.A N LYS 71.A O no hydrogen 3.031 N/A HIS 269.A N CYS 230.A O no hydrogen 3.012 N/A HIS 269.A ND1 ASN 267.A OD1 no hydrogen 2.794 N/A VAL 270.A N LEU 69.A O no hydrogen 2.777 N/A ASN 272.A N GLY 67.A O no hydrogen 3.021 N/A HIS 274.A N TYR 271.A O no hydrogen 2.856 N/A ILE 275.A N ASN 272.A O no hydrogen 3.346 N/A SER 277.A OG SER 321.A O no hydrogen 2.794 N/A LEU 278.A N HIS 274.A O no hydrogen 2.835 N/A LYS 279.A N ILE 275.A O no hydrogen 3.031 N/A LYS 279.A NZ ILE 25.A O no hydrogen 3.316 N/A ILE 280.A N ASP 276.A O no hydrogen 3.294 N/A GLN 281.A N SER 277.A O no hydrogen 3.051 N/A GLN 281.A NE2 THR 89.A OG1 no hydrogen 2.705 N/A LEU 282.A N LEU 278.A O no hydrogen 2.921 N/A ASN 283.A N ILE 280.A O no hydrogen 3.200 N/A ASN 283.A ND2 ASP 29.A O no hydrogen 2.754 N/A ASN 283.A ND2 LYS 279.A O no hydrogen 2.961 N/A ARG 284.A N GLN 281.A O no hydrogen 2.750 N/A ARG 284.A NH1 THR 89.A O no hydrogen 3.293 N/A ARG 284.A NH1 GLU 318.A O no hydrogen 2.855 N/A TYR 287.A N THR 88.A OG1 no hydrogen 2.902 N/A THR 291.A N GLN 312.A O no hydrogen 2.957 N/A THR 291.A OG1 GLN 312.A O no hydrogen 3.548 N/A LYS 293.A N THR 310.A O no hydrogen 2.925 N/A ASN 295.A N ASP 308.A O no hydrogen 2.886 N/A ASN 295.A ND2 ASP 308.A OD1 no hydrogen 2.920 N/A ASP 297.A N ASN 295.A OD1 no hydrogen 2.867 N/A ILE 298.A N ASN 295.A O no hydrogen 3.380 N/A LYS 299.A NZ GLN 252.A O no hydrogen 3.167 N/A LYS 299.A NZ ASN 255.A OD1 no hydrogen 3.259 N/A ASP 303.A N ASN 300.A O no hydrogen 2.886 N/A THR 305.A N ASP 308.A OD2 no hydrogen 2.750 N/A THR 305.A OG1 ASP 308.A OD2 no hydrogen 3.090 N/A ASP 308.A N THR 305.A O no hydrogen 2.697 N/A PHE 309.A N ILE 306.A O no hydrogen 3.409 N/A THR 310.A N LYS 293.A O no hydrogen 2.996 N/A GLN 312.A N THR 291.A O no hydrogen 2.927 N/A TYR 314.A OH LEU 87.A O no hydrogen 2.830 N/A HIS 316.A ND1 HIS 317.A O no hydrogen 2.825 N/A HIS 317.A N THR 88.A O no hydrogen 2.767 N/A HIS 317.A NE2 ILE 285.A O no hydrogen 2.798 N/A