Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3dhz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N ASN 1.A O no hydrogen 2.816 N/A ILE 7.A N TYR 3.A O no hydrogen 3.141 N/A ALA 8.A N ASP 4.A O no hydrogen 2.956 N/A ASN 9.A N GLU 5.A O no hydrogen 2.947 N/A ASN 9.A N TYR 6.A O no hydrogen 2.918 N/A HIS 10.A N ILE 7.A O no hydrogen 3.358 N/A HIS 10.A ND1 TYR 6.A O no hydrogen 2.934 N/A ASN 20.A N ASN 18.A OD1 no hydrogen 2.846 N/A LYS 26.A N ASP 24.A OD1 no hydrogen 2.960 N/A LYS 26.A NZ TYR 205.A OH no hydrogen 2.911 N/A ASP 27.A N ASP 24.A O no hydrogen 2.920 N/A LEU 28.A N GLU 25.A O no hydrogen 3.136 N/A GLU 29.A N GLU 25.A O no hydrogen 3.112 N/A VAL 30.A N LYS 26.A O no hydrogen 2.883 N/A TRP 31.A N ASP 27.A O no hydrogen 2.916 N/A ASP 32.A N LEU 28.A O no hydrogen 2.853 N/A ARG 33.A N GLU 29.A O no hydrogen 2.992 N/A LEU 34.A N VAL 30.A O no hydrogen 2.828 N/A THR 35.A N TRP 31.A O no hydrogen 2.926 N/A THR 35.A OG1 TRP 31.A O no hydrogen 2.756 N/A THR 35.A OG1 ASP 32.A O no hydrogen 3.518 N/A GLY 36.A N ASP 32.A O no hydrogen 2.833 N/A ASN 37.A N ARG 33.A O no hydrogen 2.968 N/A ASN 37.A N LEU 34.A O no hydrogen 3.277 N/A PHE 38.A N THR 35.A O no hydrogen 3.183 N/A TRP 39.A NE1 ASP 199.A OD2 no hydrogen 3.008 N/A LYS 43.A N LEU 40.A O no hydrogen 2.934 N/A ILE 44.A N PRO 41.A O no hydrogen 3.029 N/A VAL 46.A N ILE 44.A O no hydrogen 2.978 N/A ASN 48.A N PRO 45.A O no hydrogen 2.961 N/A ASP 49.A N VAL 46.A O no hydrogen 2.888 N/A ILE 50.A N SER 47.A O no hydrogen 3.219 N/A TRP 53.A N ASP 49.A O no hydrogen 2.760 N/A ASN 54.A N ILE 50.A O no hydrogen 2.787 N/A LYS 55.A N SER 52.A O no hydrogen 3.092 N/A LYS 55.A NZ GLN 51.A O no hydrogen 3.344 N/A MET 56.A N TRP 53.A O no hydrogen 2.822 N/A THR 57.A N GLU 60.A OE1 no hydrogen 2.671 N/A GLU 60.A N THR 57.A OG1 no hydrogen 2.873 N/A GLN 61.A N THR 57.A O no hydrogen 2.966 N/A GLN 61.A NE2 TRP 53.A O no hydrogen 2.849 N/A LEU 62.A N PRO 58.A O no hydrogen 2.908 N/A ALA 63.A N GLN 59.A O no hydrogen 3.088 N/A THR 64.A N GLU 60.A O no hydrogen 3.012 N/A THR 64.A OG1 GLU 60.A O no hydrogen 2.807 N/A MET 65.A N GLN 61.A O no hydrogen 2.911 N/A ARG 66.A N LEU 62.A O no hydrogen 2.907 N/A VAL 67.A N ALA 63.A O no hydrogen 2.815 N/A PHE 68.A N THR 64.A O no hydrogen 3.015 N/A THR 69.A N MET 65.A O no hydrogen 3.002 N/A THR 69.A OG1 MET 65.A O no hydrogen 2.740 N/A GLY 70.A N ARG 66.A O no hydrogen 2.970 N/A LEU 71.A N VAL 67.A O no hydrogen 2.869 N/A THR 72.A N PHE 68.A O no hydrogen 2.889 N/A THR 72.A OG1 PHE 68.A O no hydrogen 2.809 N/A LEU 73.A N THR 69.A O no hydrogen 2.935 N/A LEU 74.A N GLY 70.A O no hydrogen 3.168 N/A ASP 75.A N LEU 71.A O no hydrogen 2.941 N/A THR 76.A N THR 72.A O no hydrogen 2.835 N/A THR 76.A OG1 THR 72.A O no hydrogen 2.758 N/A ILE 77.A N LEU 73.A O no hydrogen 2.966 N/A GLN 78.A N LEU 74.A O no hydrogen 2.874 N/A GLN 78.A NE2 SER 162.A OG no hydrogen 2.614 N/A GLN 78.A NE2 GLU 166.A OE2 no hydrogen 2.950 N/A GLY 79.A N ASP 75.A O no hydrogen 2.899 N/A THR 80.A N THR 76.A O no hydrogen 3.062 N/A THR 80.A OG1 THR 76.A O no hydrogen 2.655 N/A VAL 81.A N ILE 77.A O no hydrogen 2.909 N/A GLY 82.A N ILE 77.A O no hydrogen 2.830 N/A ALA 83.A N GLN 78.A O no hydrogen 2.816 N/A SER 85.A N VAL 81.A O no hydrogen 2.964 N/A SER 85.A OG GLY 82.A O no hydrogen 2.809 N/A LEU 86.A N ALA 83.A O no hydrogen 3.060 N/A LEU 87.A N ILE 84.A O no hydrogen 3.221 N/A ASP 89.A N LEU 86.A O no hydrogen 3.178 N/A ALA 90.A N LEU 87.A O no hydrogen 3.143 N/A GLU 91.A N GLU 95.A OE1 no hydrogen 2.808 N/A THR 92.A OG1 ASP 27.A OD2 no hydrogen 2.610 N/A HIS 94.A NE2 ASN 18.A O no hydrogen 2.868 N/A GLU 95.A N THR 92.A OG1 no hydrogen 3.022 N/A GLU 96.A N THR 92.A O no hydrogen 3.253 N/A ALA 97.A N MET 93.A O no hydrogen 3.066 N/A VAL 98.A N HIS 94.A O no hydrogen 2.927 N/A TYR 99.A N GLU 95.A O no hydrogen 2.955 N/A TYR 99.A OH GLU 95.A OE2 no hydrogen 2.625 N/A THR 100.A N GLU 96.A O no hydrogen 3.161 N/A THR 100.A OG1 ALA 97.A O no hydrogen 2.678 N/A ASN 101.A N ALA 97.A O no hydrogen 3.152 N/A ILE 102.A N VAL 98.A O no hydrogen 2.891 N/A ALA 103.A N TYR 99.A O no hydrogen 2.839 N/A PHE 104.A N THR 100.A O no hydrogen 3.101 N/A MET 105.A N ASN 101.A O no hydrogen 2.811 N/A GLU 106.A N ILE 102.A O no hydrogen 2.884 N/A SER 107.A N ALA 103.A O no hydrogen 3.252 N/A SER 107.A OG ALA 103.A O no hydrogen 3.503 N/A VAL 108.A N PHE 104.A O no hydrogen 2.946 N/A HIS 109.A N MET 105.A O no hydrogen 2.767 N/A HIS 109.A NE2 ASP 199.A OD2 no hydrogen 2.718 N/A ALA 110.A N GLU 106.A O no hydrogen 2.895 N/A LYS 111.A N SER 107.A O no hydrogen 2.997 N/A LYS 111.A NZ ASN 115.A OD1 no hydrogen 3.163 N/A SER 112.A N VAL 108.A O no hydrogen 2.951 N/A SER 112.A OG VAL 108.A O no hydrogen 2.953 N/A ASN 115.A N LYS 111.A O no hydrogen 2.923 N/A ASN 115.A ND2 GLU 42.A OE2 no hydrogen 2.834 N/A ILE 116.A N SER 112.A O no hydrogen 2.922 N/A PHE 117.A N TYR 113.A O no hydrogen 2.875 N/A MET 118.A N SER 114.A O no hydrogen 2.723 N/A THR 119.A N ASN 115.A O no hydrogen 3.180 N/A THR 119.A N ILE 116.A O no hydrogen 3.213 N/A THR 119.A OG1 ASN 115.A O no hydrogen 2.704 N/A LEU 120.A N ILE 116.A O no hydrogen 2.986 N/A ALA 121.A N PHE 117.A O no hydrogen 2.899 N/A SER 122.A N GLN 125.A OE1 no hydrogen 2.871 N/A SER 122.A OG GLN 125.A OE1 no hydrogen 3.345 N/A GLN 125.A N SER 122.A OG no hydrogen 3.294 N/A GLN 125.A NE2 GLN 61.A OE1 no hydrogen 2.801 N/A ILE 126.A N SER 122.A O no hydrogen 3.013 N/A ASN 127.A N THR 123.A O no hydrogen 2.800 N/A GLU 128.A N PRO 124.A O no hydrogen 2.857 N/A ALA 129.A N GLN 125.A O no hydrogen 2.946 N/A PHE 130.A N ILE 126.A O no hydrogen 3.025 N/A ARG 131.A N ASN 127.A O no hydrogen 3.059 N/A TRP 132.A N GLU 128.A O no hydrogen 2.923 N/A SER 133.A N ALA 129.A O no hydrogen 2.948 N/A SER 133.A OG PHE 130.A O no hydrogen 2.660 N/A GLU 134.A N PHE 130.A O no hydrogen 3.164 N/A GLU 134.A N ARG 131.A O no hydrogen 3.005 N/A GLU 135.A N ARG 131.A O no hydrogen 3.007 N/A GLU 135.A N TRP 132.A O no hydrogen 3.129 N/A ASN 136.A N TRP 132.A O no hydrogen 2.890 N/A ASN 138.A ND2 ASN 240.A OD1 no hydrogen 3.044 N/A ASN 138.A ND2 GLU 243.A OE1 no hydrogen 2.928 N/A LEU 139.A N ASN 136.A OD1 no hydrogen 2.804 N/A GLN 140.A N ASN 136.A O no hydrogen 3.035 N/A GLN 140.A NE2 SER 133.A O no hydrogen 2.940 N/A ARG 141.A N GLU 137.A O no hydrogen 2.946 N/A ARG 141.A NH1 ASN 240.A OD1 no hydrogen 3.133 N/A LYS 142.A N ASN 138.A O no hydrogen 3.055 N/A LYS 142.A NZ GLU 241.A OE1 no hydrogen 2.834 N/A LYS 142.A NZ GLU 241.A OE2 no hydrogen 2.499 N/A ALA 143.A N LEU 139.A O no hydrogen 3.045 N/A LYS 144.A N GLN 140.A O no hydrogen 2.841 N/A ILE 145.A N ARG 141.A O no hydrogen 2.860 N/A ILE 146.A N LYS 142.A O no hydrogen 3.132 N/A MET 147.A N ALA 143.A O no hydrogen 2.971 N/A SER 148.A N LYS 144.A O no hydrogen 2.954 N/A SER 148.A N ILE 145.A O no hydrogen 3.185 N/A SER 148.A OG ILE 145.A O no hydrogen 2.757 N/A TYR 149.A N ILE 146.A O no hydrogen 3.052 N/A TYR 150.A N ILE 146.A O no hydrogen 3.296 N/A TYR 150.A OH GLN 78.A OE1 no hydrogen 2.593 N/A ASN 151.A N MET 147.A O no hydrogen 2.951 N/A ASN 151.A ND2 MET 147.A O no hydrogen 2.899 N/A GLY 152.A N TYR 149.A O no hydrogen 3.052 N/A LYS 157.A N ASP 154.A OD1 no hydrogen 3.089 N/A LYS 158.A N ASP 154.A O no hydrogen 3.302 N/A LYS 159.A N PRO 155.A O no hydrogen 3.332 N/A VAL 160.A N LEU 156.A O no hydrogen 2.996 N/A ALA 161.A N LYS 157.A O no hydrogen 2.850 N/A SER 162.A N LYS 158.A O no hydrogen 2.851 N/A THR 163.A N LYS 159.A O no hydrogen 2.964 N/A THR 163.A OG1 LYS 159.A O no hydrogen 2.841 N/A LEU 164.A N VAL 160.A O no hydrogen 2.891 N/A LEU 165.A N ALA 161.A O no hydrogen 2.857 N/A GLU 166.A N SER 162.A O no hydrogen 2.897 N/A SER 167.A N THR 163.A O no hydrogen 2.708 N/A PHE 168.A N LEU 164.A O no hydrogen 2.922 N/A LEU 169.A N LEU 164.A O no hydrogen 2.897 N/A TYR 171.A N PHE 168.A O no hydrogen 3.019 N/A SER 172.A OG GLU 241.A OE2 no hydrogen 2.422 N/A GLY 173.A N PHE 170.A O no hydrogen 3.026 N/A PHE 174.A N PHE 170.A O no hydrogen 3.023 N/A TYR 175.A N TYR 171.A O no hydrogen 3.130 N/A MET 178.A N PHE 174.A O no hydrogen 3.400 N/A TYR 179.A N TYR 175.A O no hydrogen 2.742 N/A LEU 180.A N LEU 176.A O no hydrogen 2.897 N/A SER 181.A N PRO 177.A O no hydrogen 2.912 N/A SER 182.A N MET 178.A O no hydrogen 3.084 N/A SER 182.A OG TYR 179.A O no hydrogen 2.887 N/A ARG 183.A N LEU 180.A O no hydrogen 2.983 N/A ALA 184.A N SER 181.A O no hydrogen 2.901 N/A LYS 185.A N LEU 180.A O no hydrogen 2.757 N/A LEU 186.A N SER 52.A OG no hydrogen 3.040 N/A ASN 188.A N ASP 49.A OD1 no hydrogen 2.965 N/A THR 189.A N ASP 49.A OD2 no hydrogen 2.605 N/A THR 189.A OG1 ASP 49.A OD2 no hydrogen 2.799 N/A ALA 190.A N LEU 186.A O no hydrogen 2.982 N/A ASP 191.A N THR 187.A O no hydrogen 3.320 N/A ASP 191.A N ASN 188.A O no hydrogen 3.008 N/A ILE 192.A N ASN 188.A O no hydrogen 3.313 N/A ILE 193.A N THR 189.A O no hydrogen 3.019 N/A ARG 194.A N ALA 190.A O no hydrogen 2.759 N/A ARG 194.A NE ASP 191.A OD1 no hydrogen 3.348 N/A ARG 194.A NH1 ASP 191.A OD1 no hydrogen 2.752 N/A ARG 194.A NH2 SER 293.A O no hydrogen 2.764 N/A LEU 195.A N ASP 191.A O no hydrogen 3.015 N/A ILE 196.A N ILE 192.A O no hydrogen 2.916 N/A ILE 197.A N ILE 193.A O no hydrogen 2.841 N/A ARG 198.A N ARG 194.A O no hydrogen 2.970 N/A ASP 199.A N LEU 195.A O no hydrogen 3.266 N/A GLU 200.A N ILE 196.A O no hydrogen 2.814 N/A SER 201.A N ILE 197.A O no hydrogen 2.832 N/A HIS 203.A N ASP 199.A O no hydrogen 2.918 N/A HIS 203.A ND1 GLU 166.A OE1 no hydrogen 3.111 N/A GLY 204.A N GLU 200.A O no hydrogen 2.803 N/A TYR 205.A N SER 201.A O no hydrogen 3.128 N/A TYR 206.A N VAL 202.A O no hydrogen 2.825 N/A TYR 206.A OH ASP 27.A OD1 no hydrogen 2.569 N/A ILE 207.A N HIS 203.A O no hydrogen 2.957 N/A GLY 208.A N GLY 204.A O no hydrogen 2.980 N/A TYR 209.A N TYR 205.A O no hydrogen 2.928 N/A TYR 209.A OH ASP 24.A OD1 no hydrogen 3.262 N/A TYR 209.A OH ASP 24.A OD2 no hydrogen 2.604 N/A LYS 210.A N TYR 206.A O no hydrogen 2.966 N/A LYS 210.A NZ ASP 27.A OD1 no hydrogen 2.774 N/A LYS 210.A NZ GLU 95.A OE1 no hydrogen 2.855 N/A TYR 211.A N ILE 207.A O no hydrogen 2.919 N/A TYR 211.A OH TYR 275.A OH no hydrogen 2.654 N/A GLN 212.A N GLY 208.A O no hydrogen 2.937 N/A GLN 212.A NE2 GLY 208.A O no hydrogen 3.679 N/A GLN 212.A NE2 ASN 272.A O no hydrogen 2.953 N/A GLN 213.A N TYR 209.A O no hydrogen 2.951 N/A GLN 213.A NE2 ASP 24.A OD2 no hydrogen 3.307 N/A GLY 214.A N LYS 210.A O no hydrogen 3.060 N/A VAL 215.A N TYR 211.A O no hydrogen 2.747 N/A LYS 216.A N GLN 212.A O no hydrogen 3.006 N/A LYS 217.A N GLY 214.A O no hydrogen 3.196 N/A LEU 218.A N VAL 215.A O no hydrogen 3.039 N/A SER 219.A N GLU 222.A OE2 no hydrogen 3.038 N/A SER 219.A OG GLU 222.A OE2 no hydrogen 3.265 N/A GLU 222.A N SER 219.A OG no hydrogen 3.124 N/A GLN 223.A N SER 219.A O no hydrogen 2.859 N/A GLU 224.A N GLU 220.A O no hydrogen 3.026 N/A GLU 225.A N ALA 221.A O no hydrogen 3.157 N/A TYR 226.A N GLU 222.A O no hydrogen 2.960 N/A TYR 226.A OH ASP 154.A OD1 no hydrogen 3.087 N/A TYR 226.A OH ASP 154.A OD2 no hydrogen 2.642 N/A LYS 227.A N GLN 223.A O no hydrogen 2.999 N/A LYS 227.A NZ GLU 276.A OE1 no hydrogen 2.678 N/A LYS 227.A NZ GLU 276.A OE2 no hydrogen 2.896 N/A ALA 228.A N GLU 224.A O no hydrogen 2.960 N/A TYR 229.A N GLU 225.A O no hydrogen 2.936 N/A THR 230.A N TYR 226.A O no hydrogen 2.947 N/A THR 230.A OG1 TYR 226.A O no hydrogen 2.878 N/A PHE 231.A N LYS 227.A O no hydrogen 3.019 N/A ASP 232.A N ALA 228.A O no hydrogen 2.948 N/A LEU 233.A N TYR 229.A O no hydrogen 2.837 N/A MET 234.A N THR 230.A O no hydrogen 2.888 N/A TYR 235.A N PHE 231.A O no hydrogen 2.894 N/A ASP 236.A N ASP 232.A O no hydrogen 3.084 N/A LEU 237.A N LEU 233.A O no hydrogen 2.899 N/A TYR 238.A N MET 234.A O no hydrogen 2.800 N/A GLU 239.A N TYR 235.A O no hydrogen 2.905 N/A ASN 240.A N ASP 236.A O no hydrogen 3.102 N/A ASN 240.A ND2 ASN 138.A O no hydrogen 2.946 N/A GLU 241.A N LEU 237.A O no hydrogen 2.852 N/A ILE 242.A N TYR 238.A O no hydrogen 2.927 N/A GLU 243.A N GLU 239.A O no hydrogen 3.450 N/A TYR 244.A N ASN 240.A O no hydrogen 3.067 N/A THR 245.A N GLU 241.A O no hydrogen 2.817 N/A THR 245.A OG1 GLU 241.A O no hydrogen 2.790 N/A GLU 246.A N ILE 242.A O no hydrogen 2.826 N/A ASP 247.A N GLU 243.A O no hydrogen 3.107 N/A ILE 248.A N TYR 244.A O no hydrogen 3.097 N/A TYR 249.A N THR 245.A O no hydrogen 2.862 N/A TYR 249.A OH SER 172.A O no hydrogen 2.649 N/A ASP 250.A N GLU 246.A O no hydrogen 2.910 N/A GLY 253.A N TYR 249.A O no hydrogen 2.704 N/A TRP 254.A N TYR 249.A O no hydrogen 3.320 N/A THR 255.A OG1 ASP 250.A OD1 no hydrogen 2.730 N/A VAL 258.A N TRP 254.A O no hydrogen 3.198 N/A LYS 259.A N THR 255.A O no hydrogen 2.965 N/A LYS 259.A NZ GLU 246.A OE2 no hydrogen 2.849 N/A ARG 260.A N GLU 256.A O no hydrogen 3.212 N/A PHE 261.A N ASP 257.A O no hydrogen 2.989 N/A LEU 262.A N VAL 258.A O no hydrogen 2.819 N/A ARG 263.A N LYS 259.A O no hydrogen 3.111 N/A ARG 263.A NE GLU 283.A O no hydrogen 2.836 N/A ARG 263.A NH1 TYR 238.A OH no hydrogen 2.919 N/A TYR 264.A N ARG 260.A O no hydrogen 2.922 N/A ASN 265.A N PHE 261.A O no hydrogen 2.940 N/A ASN 265.A ND2 PHE 261.A O no hydrogen 3.039 N/A ALA 266.A N LEU 262.A O no hydrogen 2.856 N/A ASN 267.A N ARG 263.A O no hydrogen 3.119 N/A ASN 267.A ND2 PHE 279.A O no hydrogen 2.904 N/A LYS 268.A N TYR 264.A O no hydrogen 3.214 N/A ALA 269.A N ASN 265.A O no hydrogen 2.785 N/A LEU 270.A N ALA 266.A O no hydrogen 2.999 N/A ASN 271.A N ASN 267.A O no hydrogen 2.852 N/A ASN 272.A N LYS 268.A O no hydrogen 2.947 N/A ASN 272.A ND2 SER 167.A OG no hydrogen 2.925 N/A LEU 273.A N ALA 269.A O no hydrogen 3.308 N/A LEU 273.A N LEU 270.A O no hydrogen 3.010 N/A GLY 274.A N ASN 271.A O no hydrogen 2.968 N/A TYR 275.A N LEU 270.A O no hydrogen 2.882 N/A TYR 275.A OH TYR 211.A OH no hydrogen 2.654 N/A GLU 276.A N GLU 276.A OE1 no hydrogen 2.558 N/A PHE 279.A N ASN 267.A OD1 no hydrogen 3.030 N/A GLU 283.A N PRO 280.A O no hydrogen 2.848 N/A THR 284.A N THR 281.A O no hydrogen 2.999 N/A THR 284.A OG1 THR 281.A O no hydrogen 2.796 N/A VAL 286.A N THR 284.A O no hydrogen 2.830 N/A SER 287.A N ASP 257.A OD1 no hydrogen 3.107 N/A ALA 289.A N SER 287.A OG no hydrogen 3.096 N/A ILE 290.A N SER 287.A O no hydrogen 2.923 N/A LEU 291.A N SER 287.A O no hydrogen 3.230 N/A SER 292.A N PRO 288.A O no hydrogen 2.961 N/A SER 292.A OG PRO 288.A O no hydrogen 3.149 N/A SER 292.A OG ALA 289.A O no hydrogen 3.273 N/A SER 293.A N ALA 289.A O no hydrogen 3.283 N/A SER 293.A N ILE 290.A O no hydrogen 3.029 N/A SER 293.A OG ALA 289.A O no hydrogen 3.074 N/A LEU 294.A N LEU 291.A O no hydrogen 3.257 N/A SER 295.A OG SER 292.A O no hydrogen 3.295 N/A