Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3dm6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 5.A N PHE 2P.A O no hydrogen 2.847 N/A VAL 6.A N PHE 2P.A O no hydrogen 2.905 N/A VAL 6.A N VAL 3P.A O no hydrogen 3.248 N/A ASP 7.A N SER 164.A OG no hydrogen 3.007 N/A ASN 8.A N MET 5.A O no hydrogen 3.125 N/A ASN 8.A ND2 HIS 92.A O no hydrogen 3.139 N/A ASN 8.A ND2 MET 165.A O no hydrogen 3.106 N/A LEU 9.A N GLY 163.A O no hydrogen 2.970 N/A ARG 10.A N TYR 18.A O no hydrogen 3.144 N/A GLY 11.A N VAL 161.A O no hydrogen 2.901 N/A LYS 12.A NZ GLY 115.A O no hydrogen 3.439 N/A SER 13.A OG PRO 299.A O no hydrogen 3.551 N/A GLN 15.A N LYS 12.A O no hydrogen 2.828 N/A TYR 17.A OH CYS 158.A O no hydrogen 2.446 N/A TYR 17.A OH GLU 326.A OE1 no hydrogen 2.518 N/A TYR 18.A N ARG 10.A O no hydrogen 2.912 N/A VAL 19.A N ILE 32.A O no hydrogen 2.921 N/A MET 21.A N LEU 30.A O no hydrogen 2.834 N/A THR 22.A N SER 89.A O no hydrogen 2.987 N/A THR 22.A OG1 SER 89.A OG no hydrogen 3.279 N/A VAL 23.A N GLN 28.A O no hydrogen 3.089 N/A GLY 24.A N LEU 87.A O no hydrogen 2.984 N/A SER 25.A OG THR 62.A OG1 no hydrogen 2.613 N/A GLN 28.A N VAL 23.A O no hydrogen 2.926 N/A GLN 28.A NE2 GLN 56.A O no hydrogen 2.887 N/A LEU 30.A N MET 21.A O no hydrogen 2.816 N/A ASN 31.A N GLU 119.A OE2 no hydrogen 2.838 N/A ILE 32.A N VAL 19.A O no hydrogen 2.799 N/A LEU 33.A N GLY 120.A O no hydrogen 2.848 N/A VAL 34.A N TYR 17.A O no hydrogen 2.924 N/A ASP 35.A N LEU 122.A O no hydrogen 2.730 N/A THR 36.A N SER 220.A OG no hydrogen 3.383 N/A THR 36.A OG1 VAL 218.A O no hydrogen 2.775 N/A GLY 37.A N ASP 35.A OD1 no hydrogen 2.736 N/A SER 38.A OG ASP 35.A OD2 no hydrogen 2.523 N/A SER 39.A OG TYR 126.A O no hydrogen 2.494 N/A ASN 40.A ND2 ARG 131.A O no hydrogen 2.860 N/A ALA 42.A N ILE 121.A O no hydrogen 2.986 N/A VAL 43.A N ALA 103.A O no hydrogen 3.062 N/A GLY 44.A N GLU 119.A O no hydrogen 2.943 N/A ALA 45.A N ILE 105.A O no hydrogen 2.809 N/A PHE 50.A N HIS 48.A ND1 no hydrogen 3.158 N/A LEU 51.A N HIS 48.A O no hydrogen 3.094 N/A ARG 53.A NE GLU 119.A OE1 no hydrogen 3.490 N/A ARG 53.A NE GLU 119.A OE2 no hydrogen 3.385 N/A TYR 55.A N GLY 44.A O no hydrogen 2.994 N/A TYR 55.A OH ASP 86.A OD2 no hydrogen 2.416 N/A GLN 56.A N GLN 28.A OE1 no hydrogen 3.307 N/A ARG 57.A NH1 TYR 63.A OH no hydrogen 3.305 N/A ARG 57.A NH1 GLU 82.A OE2 no hydrogen 2.498 N/A ARG 57.A NH2 GLU 82.A OE2 no hydrogen 2.826 N/A GLN 58.A N GLN 58.A OE1 no hydrogen 3.313 N/A LEU 59.A N GLN 56.A O no hydrogen 3.216 N/A SER 60.A OG THR 62.A OG1 no hydrogen 3.084 N/A SER 60.A OG ASP 86.A OD1 no hydrogen 3.528 N/A SER 60.A OG ASP 86.A OD2 no hydrogen 3.146 N/A SER 61.A N SER 25.A O no hydrogen 3.125 N/A SER 61.A OG SER 25.A O no hydrogen 3.292 N/A THR 62.A N SER 60.A OG no hydrogen 3.155 N/A THR 62.A OG1 SER 25.A OG no hydrogen 2.613 N/A THR 62.A OG1 SER 60.A OG no hydrogen 3.084 N/A THR 62.A OG1 ASP 86.A OD1 no hydrogen 3.072 N/A TYR 63.A N SER 60.A O no hydrogen 3.470 N/A ARG 64.A N THR 85.A O no hydrogen 3.362 N/A LEU 66.A N LEU 83.A O no hydrogen 3.168 N/A ARG 67.A N ASP 65.A OD1 no hydrogen 2.588 N/A VAL 70.A N GLY 81.A O no hydrogen 2.810 N/A VAL 72.A N TRP 79.A O no hydrogen 2.632 N/A TYR 74.A N GLY 77.A O no hydrogen 2.910 N/A LYS 78.A N ASP 109.A O no hydrogen 2.874 N/A LYS 78.A NZ ASP 109.A OD2 no hydrogen 2.910 N/A TRP 79.A N VAL 72.A O no hydrogen 3.100 N/A TRP 79.A NE1 TYR 74.A OH no hydrogen 2.983 N/A GLU 80.A N GLU 107.A O no hydrogen 3.128 N/A GLY 81.A N VAL 70.A O no hydrogen 2.729 N/A GLU 82.A N ALA 104.A O no hydrogen 2.868 N/A LEU 83.A N LYS 68.A O no hydrogen 2.959 N/A GLY 84.A N ILE 102.A O no hydrogen 2.919 N/A THR 85.A N ARG 64.A O no hydrogen 3.264 N/A ASP 86.A N ALA 100.A O no hydrogen 3.096 N/A LEU 87.A N ASP 86.A OD1 no hydrogen 2.678 N/A VAL 88.A N VAL 98.A O no hydrogen 2.733 N/A SER 89.A N THR 22.A O no hydrogen 3.110 N/A SER 89.A OG THR 22.A OG1 no hydrogen 3.279 N/A GLY 93.A N ILE 90.A O no hydrogen 2.707 N/A VAL 98.A N VAL 88.A O no hydrogen 2.777 N/A ARG 99.A N GLN 146.A OE1 no hydrogen 2.716 N/A ARG 99.A NH1 THR 62.A O no hydrogen 3.464 N/A ARG 99.A NH1 THR 85.A OG1 no hydrogen 2.225 N/A ARG 99.A NH2 THR 62.A O no hydrogen 2.714 N/A ALA 100.A N ASP 86.A O no hydrogen 2.914 N/A ASN 101.A ND2 GLU 137.A O no hydrogen 2.646 N/A ILE 102.A N GLY 84.A O no hydrogen 2.580 N/A ALA 103.A N PHE 41.A O no hydrogen 3.069 N/A ALA 104.A N GLU 82.A O no hydrogen 2.676 N/A ILE 105.A N VAL 43.A O no hydrogen 2.712 N/A THR 106.A N GLU 80.A O no hydrogen 3.334 N/A ASP 109.A N LYS 78.A O no hydrogen 2.727 N/A LYS 110.A NZ ASP 109.A OD1 no hydrogen 3.479 N/A SER 116.A N ILE 113.A O no hydrogen 3.080 N/A SER 116.A OG ILE 113.A O no hydrogen 3.145 N/A ASN 117.A ND2 TYR 18.A OH no hydrogen 3.034 N/A TRP 118.A N SER 116.A OG no hydrogen 3.309 N/A TRP 118.A NE1 GLN 15.A O no hydrogen 2.879 N/A GLU 119.A N ASN 31.A O no hydrogen 2.737 N/A ILE 121.A N ALA 42.A O no hydrogen 2.694 N/A LEU 122.A N LEU 33.A O no hydrogen 2.642 N/A GLY 123.A N ASN 40.A O no hydrogen 3.123 N/A LEU 124.A N ASP 35.A O no hydrogen 2.813 N/A ALA 125.A N SER 38.A O no hydrogen 2.671 N/A TYR 126.A N TRP 188.A O no hydrogen 2.980 N/A ILE 129.A N TYR 126.A O no hydrogen 3.285 N/A ALA 130.A N ALA 127.A O no hydrogen 2.882 N/A ARG 131.A N ASN 40.A OD1 no hydrogen 2.923 N/A SER 135.A N ASP 133.A OD2 no hydrogen 2.860 N/A SER 135.A OG ASP 133.A OD2 no hydrogen 2.417 N/A LEU 136.A N ASP 133.A O no hydrogen 3.264 N/A ASP 141.A N PRO 138.A O no hydrogen 2.704 N/A SER 142.A N PRO 138.A O no hydrogen 3.134 N/A SER 142.A OG GLU 137.A OE2 no hydrogen 3.128 N/A SER 142.A OG PRO 138.A O no hydrogen 3.546 N/A LEU 143.A N PHE 139.A O no hydrogen 2.935 N/A VAL 144.A N PHE 140.A O no hydrogen 3.234 N/A LYS 145.A N ASP 141.A O no hydrogen 3.044 N/A GLN 146.A N SER 142.A O no hydrogen 2.786 N/A GLN 146.A NE2 ARG 99.A O no hydrogen 2.820 N/A THR 147.A OG1 LEU 143.A O no hydrogen 2.658 N/A VAL 149.A N THR 147.A OG1 no hydrogen 3.011 N/A PHE 153.A N PHE 332.A O no hydrogen 3.329 N/A SER 154.A N ILE 166.A O no hydrogen 2.868 N/A SER 154.A OG ILE 166.A O no hydrogen 3.512 N/A SER 154.A OG TYR 329.A OH no hydrogen 2.860 N/A LEU 155.A N VAL 330.A O no hydrogen 2.685 N/A GLN 156.A N SER 164.A O no hydrogen 2.769 N/A GLN 156.A NE2 LEU 174.A O no hydrogen 3.571 N/A CYS 158.A N GLY 162.A O no hydrogen 2.819 N/A SER 164.A N GLN 156.A O no hydrogen 2.720 N/A SER 164.A OG GLN 156.A OE1 no hydrogen 2.445 N/A MET 165.A N ASN 8.A OD1 no hydrogen 2.735 N/A ILE 166.A N SER 154.A O no hydrogen 3.010 N/A GLY 168.A N LEU 152.A O no hydrogen 2.713 N/A ASP 171.A N TYR 329.A OH no hydrogen 3.275 N/A SER 173.A OG ASP 171.A OD2 no hydrogen 2.425 N/A LEU 174.A N ASP 171.A O no hydrogen 3.341 N/A TYR 175.A OH HIS 172.A ND1 no hydrogen 2.997 N/A THR 176.A N VAL 343.A O no hydrogen 3.160 N/A TRP 180.A N PHE 341.A O no hydrogen 2.915 N/A THR 182.A N ILE 339.A O no hydrogen 2.818 N/A THR 182.A OG1 MET 279.A O no hydrogen 2.583 N/A ILE 184.A N LYS 337.A O no hydrogen 2.816 N/A ARG 185.A N GLU 191.A O no hydrogen 2.846 N/A ARG 185.A NH1 GLU 191.A OE2 no hydrogen 2.995 N/A ARG 185.A NH1 TYR 368.A O no hydrogen 3.146 N/A ARG 185.A NH2 TYR 368.A O no hydrogen 3.058 N/A ARG 186.A NE GLU 128.A OE1 no hydrogen 3.207 N/A ARG 186.A NH2 GLU 128.A OE1 no hydrogen 3.334 N/A ARG 186.A NH2 GLU 128.A OE2 no hydrogen 2.767 N/A TRP 188.A N ARG 186.A O no hydrogen 3.016 N/A TRP 188.A N TYR 189.A O no hydrogen 3.128 N/A TRP 188.A NE1 GLU 191.A OE1 no hydrogen 2.867 N/A TYR 190.A OH LEU 124.A O no hydrogen 2.586 N/A VAL 192.A N SER 216.A O no hydrogen 3.018 N/A ILE 194.A N ASN 212.A OD1 no hydrogen 2.743 N/A VAL 195.A N TYR 277.A O no hydrogen 2.704 N/A ARG 196.A NE GLU 198.A OE2 no hydrogen 3.441 N/A GLU 198.A N SER 275.A O no hydrogen 3.018 N/A ILE 199.A N GLN 202.A O no hydrogen 2.788 N/A ASN 200.A N VAL 273.A O no hydrogen 3.017 N/A GLN 202.A N ILE 199.A O no hydrogen 2.925 N/A LEU 204.A N VAL 197.A O no hydrogen 3.182 N/A LYS 205.A N ASP 203.A OD1 no hydrogen 2.823 N/A LYS 209.A N ASP 207.A OD1 no hydrogen 3.463 N/A LYS 209.A NZ ASP 365.A O no hydrogen 2.600 N/A GLU 210.A N ASP 207.A O no hydrogen 2.682 N/A ASN 212.A N LYS 209.A O no hydrogen 3.379 N/A ASN 212.A ND2 ILE 194.A O no hydrogen 2.736 N/A ASN 212.A ND2 CYS 208.A O no hydrogen 2.950 N/A ASN 212.A ND2 CYS 366.A O no hydrogen 3.142 N/A TYR 213.A N GLU 210.A O no hydrogen 3.454 N/A ASP 214.A N ASP 214.A OD2 no hydrogen 2.578 N/A LYS 215.A NZ THR 316.A O no hydrogen 2.845 N/A SER 216.A OG TYR 211.A O no hydrogen 3.094 N/A SER 216.A OG ASN 212.A OD1 no hydrogen 2.594 N/A ILE 217.A N THR 318.A O no hydrogen 3.060 N/A VAL 218.A N TYR 190.A O no hydrogen 2.998 N/A ASP 219.A N MET 320.A O no hydrogen 3.091 N/A SER 220.A N THR 36.A OG1 no hydrogen 2.792 N/A SER 220.A OG VAL 34.A O no hydrogen 2.486 N/A GLY 221.A N ASP 219.A OD1 no hydrogen 2.750 N/A THR 222.A N ASP 219.A O no hydrogen 3.244 N/A THR 222.A OG1 ASP 219.A OD2 no hydrogen 2.650 N/A ASN 224.A ND2 SER 312.A OG no hydrogen 2.585 N/A LEU 225.A N ALA 310.A O no hydrogen 3.260 N/A ARG 226.A N VAL 319.A O no hydrogen 3.032 N/A ARG 226.A NH2 GLN 313.A O no hydrogen 3.382 N/A LEU 227.A N SER 312.A O no hydrogen 2.848 N/A LYS 229.A NZ GLU 233.A OE2 no hydrogen 2.728 N/A LYS 230.A NZ GLU 210.A OE2 no hydrogen 3.539 N/A PHE 232.A N PRO 228.A O no hydrogen 2.836 N/A GLU 233.A N LYS 229.A O no hydrogen 3.204 N/A ALA 234.A N LYS 230.A O no hydrogen 3.153 N/A ALA 235.A N VAL 231.A O no hydrogen 3.027 N/A ALA 235.A N PHE 232.A O no hydrogen 3.034 N/A VAL 236.A N PHE 232.A O no hydrogen 2.915 N/A LYS 237.A N GLU 233.A O no hydrogen 2.982 N/A SER 238.A N ALA 235.A O no hydrogen 3.081 N/A SER 238.A OG ALA 234.A O no hydrogen 3.019 N/A ILE 239.A N ALA 235.A O no hydrogen 2.935 N/A ILE 239.A N VAL 236.A O no hydrogen 2.780 N/A LYS 240.A N VAL 236.A O no hydrogen 2.714 N/A ALA 241.A N LYS 237.A O no hydrogen 3.077 N/A ALA 242.A N SER 238.A O no hydrogen 3.161 N/A SER 243.A N LYS 240.A O no hydrogen 2.873 N/A SER 243.A OG ILE 239.A O no hydrogen 2.556 N/A SER 243.A OG LYS 240.A O no hydrogen 3.291 N/A SER 244.A N ALA 241.A O no hydrogen 3.406 N/A SER 244.A OG ALA 241.A O no hydrogen 3.373 N/A LYS 247.A NZ GLU 246.A OE2 no hydrogen 2.564 N/A PHE 252.A N PRO 249.A O no hydrogen 2.732 N/A LEU 254.A N GLY 251.A O no hydrogen 2.992 N/A GLY 255.A N PHE 252.A O no hydrogen 3.041 N/A GLU 256.A N GLY 251.A O no hydrogen 3.312 N/A VAL 259.A N TYR 307.A O no hydrogen 3.262 N/A TRP 261.A N ASP 305.A O no hydrogen 2.820 N/A TRP 261.A NE1 GLU 246.A OE2 no hydrogen 2.736 N/A GLY 264.A N ASP 305.A OD2 no hydrogen 3.373 N/A THR 265.A N GLN 262.A O no hydrogen 3.025 N/A THR 265.A OG1 GLN 262.A O no hydrogen 2.715 N/A THR 266.A OG1 TYR 307.A OH no hydrogen 3.199 N/A ILE 270.A N PRO 267.A O no hydrogen 2.922 N/A PHE 271.A N TRP 268.A O no hydrogen 2.837 N/A VAL 273.A N ASN 200.A OD1 no hydrogen 3.435 N/A ILE 274.A N ILE 291.A O no hydrogen 2.891 N/A SER 275.A N GLU 198.A O no hydrogen 2.688 N/A SER 275.A OG THR 290.A OG1 no hydrogen 2.878 N/A LEU 276.A N ILE 289.A O no hydrogen 2.765 N/A TYR 277.A N ARG 196.A O no hydrogen 2.781 N/A TYR 277.A OH GLU 198.A OE1 no hydrogen 2.782 N/A LEU 278.A N PHE 287.A O no hydrogen 2.818 N/A MET 279.A N ILE 193.A O no hydrogen 2.993 N/A VAL 282.A N GLN 285.A OE1 no hydrogen 3.097 N/A GLN 285.A N VAL 282.A O no hydrogen 3.138 N/A SER 286.A N PHE 361.A O no hydrogen 3.216 N/A PHE 287.A N LEU 278.A O no hydrogen 3.028 N/A ARG 288.A N GLU 358.A O no hydrogen 2.838 N/A ARG 288.A NE GLU 358.A OE2 no hydrogen 3.180 N/A ARG 288.A NH1 TYR 277.A OH no hydrogen 3.105 N/A ARG 288.A NH2 GLU 358.A OE2 no hydrogen 2.605 N/A ILE 289.A N LEU 276.A O no hydrogen 2.955 N/A THR 290.A N ALA 356.A O no hydrogen 2.882 N/A THR 290.A OG1 SER 275.A OG no hydrogen 2.878 N/A ILE 291.A N ILE 274.A O no hydrogen 2.587 N/A GLN 294.A N GLN 294.A OE1 no hydrogen 2.581 N/A GLN 294.A NE2 ASP 350.A OD2 no hydrogen 3.163 N/A GLN 295.A N LEU 292.A O no hydrogen 2.897 N/A GLN 295.A NE2 LEU 292.A O no hydrogen 3.665 N/A TYR 296.A OH PRO 272.A O no hydrogen 2.488 N/A LEU 297.A N PRO 293.A O no hydrogen 3.053 N/A ARG 298.A N LYS 308.A O no hydrogen 2.782 N/A VAL 300.A N CYS 306.A O no hydrogen 2.961 N/A ASP 305.A N TRP 261.A O no hydrogen 2.802 N/A TYR 307.A N VAL 259.A O no hydrogen 2.993 N/A TYR 307.A OH THR 266.A OG1 no hydrogen 3.199 N/A LYS 308.A N ARG 298.A O no hydrogen 2.705 N/A ALA 310.A N TYR 296.A O no hydrogen 2.783 N/A SER 312.A N LEU 225.A O no hydrogen 2.963 N/A SER 314.A N LEU 227.A O no hydrogen 2.875 N/A SER 314.A OG GLY 317.A O no hydrogen 2.780 N/A THR 316.A N SER 314.A OG no hydrogen 3.047 N/A THR 318.A N LYS 215.A O no hydrogen 2.836 N/A THR 318.A OG1 TYR 211.A O no hydrogen 2.677 N/A VAL 319.A N ARG 226.A O no hydrogen 3.001 N/A MET 320.A N ILE 217.A O no hydrogen 2.781 N/A ALA 322.A N THR 222.A O no hydrogen 2.889 N/A VAL 323.A N THR 223.A O no hydrogen 3.016 N/A ILE 324.A N GLY 321.A O no hydrogen 3.084 N/A MET 325.A N GLY 321.A O no hydrogen 2.951 N/A GLU 326.A N ALA 322.A O no hydrogen 2.796 N/A TYR 329.A N ALA 342.A O no hydrogen 2.618 N/A VAL 330.A N LEU 155.A O no hydrogen 3.061 N/A VAL 331.A N GLY 340.A O no hydrogen 2.789 N/A PHE 332.A N PHE 153.A O no hydrogen 2.811 N/A ASP 333.A N ARG 338.A O no hydrogen 2.901 N/A ARG 334.A N PHE 332.A O no hydrogen 3.124 N/A ARG 334.A NE ASN 151.A OD1 no hydrogen 2.949 N/A ARG 334.A NH1 TYR 190.A OH no hydrogen 3.099 N/A ARG 334.A NH2 ASP 141.A OD2 no hydrogen 3.111 N/A ALA 335.A N ASN 151.A O no hydrogen 3.138 N/A ARG 336.A N ASP 333.A O no hydrogen 3.145 N/A ARG 336.A N ASP 333.A OD1 no hydrogen 3.076 N/A LYS 337.A N ARG 334.A O no hydrogen 2.941 N/A ARG 338.A N ASP 333.A O no hydrogen 3.025 N/A ARG 338.A NE ASP 333.A OD2 no hydrogen 2.575 N/A ARG 338.A NH1 GLU 281.A OE2 no hydrogen 2.527 N/A ARG 338.A NH2 ASP 333.A OD2 no hydrogen 3.095 N/A ILE 339.A N THR 182.A O no hydrogen 2.583 N/A GLY 340.A N VAL 331.A O no hydrogen 2.732 N/A PHE 341.A N TRP 180.A O no hydrogen 2.711 N/A ALA 342.A N TYR 329.A O no hydrogen 2.991 N/A CYS 346.A SG SER 344.A OG no hydrogen 3.770 N/A HIS 347.A N SER 344.A O no hydrogen 3.208 N/A PHE 352.A N ASP 350.A OD1 no hydrogen 2.628 N/A ARG 353.A NH1 PHE 271.A O no hydrogen 2.435 N/A ARG 353.A NH2 TRP 268.A O no hydrogen 2.981 N/A ARG 353.A NH2 PHE 271.A O no hydrogen 3.319 N/A GLU 358.A N ARG 288.A O no hydrogen 2.810 N/A THR 363.A N ASN 284.A O no hydrogen 3.189 N/A