Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3ea3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A N GLU 6.A OE1 no hydrogen 2.699 N/A SER 3.A OG ASN 5.A OD1 no hydrogen 2.570 N/A GLU 6.A N SER 3.A O no hydrogen 2.977 N/A LEU 7.A N VAL 4.A O no hydrogen 3.047 N/A GLU 8.A N ASN 5.A O no hydrogen 2.872 N/A ASN 9.A N GLU 6.A O no hydrogen 3.354 N/A SER 11.A N ASN 9.A OD1 no hydrogen 2.855 N/A SER 11.A OG ASP 60.A OD1 no hydrogen 2.785 N/A LYS 12.A N ASN 9.A O no hydrogen 2.998 N/A LYS 12.A NZ ASP 104.A O no hydrogen 3.158 N/A LYS 12.A NZ ASN 105.A OD1 no hydrogen 2.711 N/A TRP 13.A NE1 GLY 62.A O no hydrogen 2.937 N/A MET 14.A N GLU 108.A OE1 no hydrogen 3.053 N/A MET 14.A N GLU 108.A OE2 no hydrogen 3.221 N/A GLN 15.A N LYS 12.A O no hydrogen 3.027 N/A ILE 17.A N MET 14.A O no hydrogen 3.157 N/A ILE 21.A N PRO 18.A O no hydrogen 3.292 N/A LEU 23.A N ILE 149.A O no hydrogen 2.805 N/A ARG 25.A N PRO 22.A O no hydrogen 2.892 N/A ARG 25.A NE SER 222.A O no hydrogen 2.695 N/A ARG 25.A NH1 ARG 25.A O no hydrogen 2.711 N/A ARG 25.A NH1 THR 266.A O no hydrogen 3.285 N/A ARG 25.A NH2 THR 266.A O no hydrogen 3.054 N/A ILE 26.A N LEU 23.A O no hydrogen 3.130 N/A SER 27.A N ASN 292.A OD1 no hydrogen 3.040 N/A ILE 28.A N GLY 269.A O no hydrogen 3.067 N/A GLY 30.A N VAL 271.A O no hydrogen 2.842 N/A THR 31.A N ILE 65.A O no hydrogen 3.000 N/A THR 31.A OG1 SER 34.A OG no hydrogen 2.674 N/A THR 31.A OG1 GLN 58.A OE1 no hydrogen 2.820 N/A HIS 32.A N GLN 273.A O no hydrogen 2.944 N/A HIS 32.A ND1 ASP 274.A OD1 no hydrogen 2.866 N/A ASP 33.A N ASP 67.A OD2 no hydrogen 2.961 N/A SER 34.A N ASP 67.A O no hydrogen 3.227 N/A SER 34.A OG THR 31.A O no hydrogen 2.862 N/A SER 34.A OG THR 31.A OG1 no hydrogen 2.674 N/A THR 36.A N ASP 33.A O no hydrogen 3.355 N/A THR 36.A OG1 ASP 33.A O no hydrogen 3.148 N/A THR 36.A OG1 THR 50.A OG1 no hydrogen 2.777 N/A LYS 38.A NZ TYR 88.A O no hydrogen 3.024 N/A LYS 38.A NZ GLU 93.A OE2 no hydrogen 3.021 N/A LEU 39.A N THR 36.A O no hydrogen 3.433 N/A ILE 43.A N ASN 41.A OD1 no hydrogen 2.761 N/A LYS 44.A N ASN 41.A OD1 no hydrogen 3.317 N/A GLN 45.A N ASN 41.A O no hydrogen 2.888 N/A GLN 45.A NE2 LEU 39.A O no hydrogen 3.129 N/A VAL 46.A N PRO 42.A O no hydrogen 3.112 N/A TRP 47.A N ILE 43.A O no hydrogen 3.385 N/A GLY 48.A N LYS 44.A O no hydrogen 2.597 N/A MET 49.A N GLN 45.A O no hydrogen 3.039 N/A THR 50.A N THR 36.A OG1 no hydrogen 2.880 N/A THR 50.A OG1 HIS 32.A O no hydrogen 2.897 N/A THR 50.A OG1 THR 36.A OG1 no hydrogen 2.777 N/A GLN 51.A NE2 HIS 32.A O no hydrogen 3.196 N/A GLN 51.A NE2 GLN 273.A O no hydrogen 3.082 N/A ARG 56.A NE ASP 60.A OD2 no hydrogen 2.797 N/A ARG 56.A NH2 ASP 104.A OD2 no hydrogen 2.991 N/A TYR 57.A N ASP 54.A OD1 no hydrogen 3.113 N/A GLN 58.A N ASP 54.A O no hydrogen 3.082 N/A GLN 58.A NE2 SER 34.A O no hydrogen 3.265 N/A GLN 58.A NE2 TYR 53.A O no hydrogen 2.834 N/A MET 59.A N PHE 55.A O no hydrogen 2.867 N/A ASP 60.A N ARG 56.A O no hydrogen 2.820 N/A HIS 61.A N GLN 58.A O no hydrogen 3.152 N/A HIS 61.A ND1 TYR 57.A O no hydrogen 2.787 N/A HIS 61.A NE2 GLU 278.A OE2 no hydrogen 2.815 N/A GLY 62.A N MET 59.A O no hydrogen 3.023 N/A ALA 63.A N GLN 58.A O no hydrogen 3.060 N/A ARG 64.A N PRO 29.A O no hydrogen 2.974 N/A ARG 64.A NE GLU 108.A OE1 no hydrogen 2.918 N/A ARG 64.A NH1 MET 59.A O no hydrogen 2.867 N/A ARG 64.A NH1 ALA 63.A O no hydrogen 3.052 N/A ARG 64.A NH2 TRP 10.A O no hydrogen 2.882 N/A ARG 64.A NH2 GLU 108.A OE1 no hydrogen 2.938 N/A ILE 65.A N PRO 29.A O no hydrogen 3.379 N/A PHE 66.A N ILE 111.A O no hydrogen 2.888 N/A ASP 67.A N THR 31.A O no hydrogen 3.328 N/A ASP 67.A N SER 34.A OG no hydrogen 2.931 N/A ILE 68.A N SER 113.A O no hydrogen 2.953 N/A ARG 69.A NE ASP 67.A OD1 no hydrogen 2.736 N/A ARG 69.A NH1 GLU 117.A OE1 no hydrogen 3.056 N/A ARG 69.A NH2 ASP 67.A OD2 no hydrogen 3.240 N/A GLY 70.A N LYS 115.A O no hydrogen 2.960 N/A ARG 71.A N VAL 79.A O no hydrogen 2.715 N/A ARG 71.A NE GLU 119.A O no hydrogen 2.816 N/A ARG 71.A NH2 GLU 119.A O no hydrogen 3.455 N/A THR 73.A N THR 77.A O no hydrogen 2.882 N/A THR 73.A OG1 THR 77.A O no hydrogen 3.221 N/A THR 73.A OG1 THR 77.A OG1 no hydrogen 2.647 N/A ASP 75.A N THR 73.A OG1 no hydrogen 3.168 N/A THR 77.A N THR 73.A OG1 no hydrogen 3.343 N/A THR 77.A OG1 THR 73.A OG1 no hydrogen 2.647 N/A ILE 78.A N TYR 136.A OH no hydrogen 3.040 N/A VAL 79.A N ARG 71.A O no hydrogen 2.977 N/A LEU 80.A N VAL 89.A O no hydrogen 2.865 N/A HIS 81.A N ARG 69.A O no hydrogen 2.892 N/A HIS 81.A ND1 LEU 80.A O no hydrogen 3.104 N/A HIS 82.A N LEU 85.A O no hydrogen 3.060 N/A HIS 82.A ND1 GLY 48.A O no hydrogen 2.686 N/A GLY 83.A N GLU 117.A OE2 no hydrogen 2.792 N/A LEU 85.A N HIS 82.A O no hydrogen 3.172 N/A LEU 87.A N LEU 80.A O no hydrogen 3.128 N/A THR 90.A N GLU 93.A OE1 no hydrogen 3.365 N/A LEU 91.A N ILE 78.A O no hydrogen 3.048 N/A GLU 93.A N THR 90.A OG1 no hydrogen 3.066 N/A PHE 94.A N THR 90.A O no hydrogen 3.229 N/A ILE 95.A N LEU 91.A O no hydrogen 3.054 N/A ASN 96.A N HIS 92.A O no hydrogen 2.955 N/A GLU 97.A N GLU 93.A O no hydrogen 3.170 N/A ALA 98.A N PHE 94.A O no hydrogen 2.961 N/A LYS 99.A N ILE 95.A O no hydrogen 2.894 N/A LYS 99.A NZ ASP 139.A OD2 no hydrogen 2.507 N/A GLN 100.A N ASN 96.A O no hydrogen 3.077 N/A PHE 101.A N GLU 97.A O no hydrogen 3.029 N/A LEU 102.A N ALA 98.A O no hydrogen 2.829 N/A LYS 103.A N LYS 99.A O no hydrogen 2.925 N/A ASP 104.A N GLN 100.A O no hydrogen 3.034 N/A ASN 105.A N PHE 101.A O no hydrogen 2.837 N/A ASN 105.A ND2 PHE 101.A O no hydrogen 3.261 N/A SER 107.A OG GLU 108.A OE2 no hydrogen 2.564 N/A GLU 108.A N ASN 105.A O no hydrogen 3.053 N/A THR 109.A OG1 ALA 154.A O no hydrogen 2.944 N/A THR 109.A OG1 LYS 157.A O no hydrogen 2.912 N/A ILE 110.A N LYS 157.A O no hydrogen 3.198 N/A ILE 111.A N ARG 64.A O no hydrogen 2.764 N/A MET 112.A N VAL 159.A O no hydrogen 2.773 N/A SER 113.A N PHE 66.A O no hydrogen 2.810 N/A LEU 114.A N LEU 161.A O no hydrogen 3.009 N/A LYS 115.A N ILE 68.A O no hydrogen 3.124 N/A LYS 115.A NZ LYS 116.A O no hydrogen 3.507 N/A LYS 116.A NZ ASP 120.A OD2 no hydrogen 3.260 N/A GLU 117.A N GLY 70.A O no hydrogen 2.846 N/A MET 121.A N LEU 72.A O no hydrogen 2.942 N/A SER 127.A N SER 130.A OG no hydrogen 2.822 N/A SER 127.A OG SER 129.A OG no hydrogen 3.089 N/A SER 127.A OG SER 130.A OG no hydrogen 3.165 N/A SER 129.A OG SER 127.A OG no hydrogen 3.089 N/A SER 129.A OG GLY 166.A O no hydrogen 3.505 N/A SER 130.A N SER 127.A OG no hydrogen 3.153 N/A SER 130.A OG SER 127.A O no hydrogen 3.212 N/A SER 130.A OG SER 127.A OG no hydrogen 3.165 N/A THR 131.A N SER 127.A O no hydrogen 2.988 N/A THR 131.A OG1 SER 127.A O no hydrogen 2.633 N/A PHE 132.A N PHE 128.A O no hydrogen 3.131 N/A GLU 133.A N SER 129.A O no hydrogen 3.027 N/A LYS 134.A N SER 130.A O no hydrogen 2.955 N/A LYS 134.A NZ ASN 135.A OD1 no hydrogen 2.827 N/A ASN 135.A N THR 131.A O no hydrogen 2.976 N/A ASN 135.A ND2 THR 131.A O no hydrogen 3.219 N/A TYR 136.A N PHE 132.A O no hydrogen 2.896 N/A PHE 137.A N PHE 132.A O no hydrogen 2.867 N/A ASP 139.A N TYR 136.A O no hydrogen 3.029 N/A ILE 141.A N ASP 139.A OD1 no hydrogen 2.754 N/A PHE 142.A N ASP 139.A O no hydrogen 3.082 N/A LEU 143.A N ILE 158.A O no hydrogen 2.999 N/A LYS 144.A NZ PHE 137.A O no hydrogen 3.135 N/A LYS 144.A NZ ASP 139.A O no hydrogen 3.009 N/A LYS 144.A NZ PHE 142.A O no hydrogen 2.945 N/A ASN 148.A ND2 LEU 225.A O no hydrogen 2.980 N/A LEU 151.A N ILE 21.A O no hydrogen 2.899 N/A GLY 152.A N ASP 19.A O no hydrogen 2.831 N/A ASP 153.A N LYS 150.A O no hydrogen 3.180 N/A ALA 154.A N LYS 150.A O no hydrogen 3.203 N/A ALA 154.A N LEU 151.A O no hydrogen 2.781 N/A ARG 155.A N LEU 151.A O no hydrogen 2.991 N/A ARG 155.A NE ASP 19.A OD1 no hydrogen 2.900 N/A ARG 155.A NH1 MET 14.A O no hydrogen 3.013 N/A ARG 155.A NH1 SER 107.A O no hydrogen 2.764 N/A ARG 155.A NH2 ILE 17.A O no hydrogen 2.564 N/A ARG 155.A NH2 ASP 19.A OD1 no hydrogen 2.799 N/A GLY 156.A N GLU 108.A O no hydrogen 2.710 N/A LYS 157.A N ALA 154.A O no hydrogen 2.964 N/A LYS 157.A NZ ASP 153.A O no hydrogen 3.516 N/A ILE 158.A N ILE 141.A O no hydrogen 2.920 N/A VAL 159.A N ILE 110.A O no hydrogen 2.660 N/A LEU 161.A N MET 112.A O no hydrogen 2.900 N/A LYS 162.A N TYR 173.A O no hydrogen 3.154 N/A LYS 162.A NZ SER 167.A OG no hydrogen 2.767 N/A LYS 162.A NZ GLU 169.A O no hydrogen 2.891 N/A ARG 163.A N LEU 114.A O no hydrogen 2.936 N/A SER 167.A OG GLU 133.A OE2 no hydrogen 3.482 N/A SER 167.A OG GLU 169.A O no hydrogen 3.411 N/A ASN 168.A N GLU 133.A OE2 no hydrogen 2.600 N/A GLU 169.A N GLU 133.A OE2 no hydrogen 3.029 N/A SER 170.A OG LYS 144.A O no hydrogen 3.214 N/A GLY 171.A N GLU 146.A OE2 no hydrogen 3.081 N/A GLY 172.A N THR 145.A O no hydrogen 3.011 N/A TYR 173.A N LEU 160.A O no hydrogen 2.825 N/A ASN 174.A N ASN 189.A OD1 no hydrogen 2.906 N/A ASN 174.A ND2 GLU 146.A OE1 no hydrogen 3.359 N/A TRP 178.A NE1 ASP 198.A OD2 no hydrogen 3.082 N/A PHE 184.A N VAL 196.A O no hydrogen 2.899 N/A THR 185.A OG1 THR 195.A OG1 no hydrogen 2.969 N/A THR 186.A N VAL 194.A O no hydrogen 2.864 N/A THR 187.A N THR 186.A OG1 no hydrogen 2.632 N/A VAL 188.A N VAL 192.A O no hydrogen 2.679 N/A ASN 189.A ND2 GLY 147.A O no hydrogen 2.999 N/A ASN 189.A ND2 GLY 172.A O no hydrogen 3.096 N/A ASN 191.A N ASN 189.A O no hydrogen 2.604 N/A VAL 192.A N VAL 188.A O no hydrogen 3.077 N/A ASN 193.A N ASN 226.A O no hydrogen 2.933 N/A VAL 194.A N THR 186.A O no hydrogen 2.776 N/A THR 195.A N LEU 228.A O no hydrogen 2.733 N/A THR 195.A OG1 THR 185.A OG1 no hydrogen 2.969 N/A THR 195.A OG1 HIS 227.A NE2 no hydrogen 2.861 N/A VAL 196.A N PHE 184.A O no hydrogen 2.846 N/A GLN 197.A N ILE 230.A O no hydrogen 2.851 N/A GLN 197.A NE2 ASN 231.A OD1 no hydrogen 2.685 N/A GLN 197.A NE2 PHE 232.A O no hydrogen 2.787 N/A ASP 198.A N GLU 182.A O no hydrogen 3.007 N/A LYS 199.A N GLN 197.A OE1 no hydrogen 2.993 N/A LYS 199.A NZ GLU 206.A OE2 no hydrogen 3.539 N/A LYS 199.A NZ SER 210.A OG no hydrogen 3.056 N/A TYR 200.A OH ASP 180.A OD1 no hydrogen 2.495 N/A TYR 200.A OH ASP 180.A OD2 no hydrogen 2.598 N/A LYS 201.A N ASN 181.A OD1 no hydrogen 3.015 N/A TYR 204.A OH SER 251.A OG no hydrogen 2.831 N/A GLU 206.A N ASN 203.A OD1 no hydrogen 2.588 N/A LYS 207.A N ASN 203.A O no hydrogen 2.995 N/A LYS 207.A NZ GLN 197.A OE1 no hydrogen 2.919 N/A LYS 207.A NZ LYS 199.A O no hydrogen 3.141 N/A LYS 207.A NZ PHE 232.A O no hydrogen 2.746 N/A LYS 207.A NZ SER 234.A O no hydrogen 3.082 N/A VAL 208.A N TYR 204.A O no hydrogen 3.061 N/A LYS 209.A N ASP 205.A O no hydrogen 3.089 N/A LYS 209.A NZ ASP 213.A OD2 no hydrogen 3.203 N/A SER 210.A N GLU 206.A O no hydrogen 2.984 N/A SER 210.A OG GLU 206.A O no hydrogen 2.763 N/A ILE 211.A N LYS 207.A O no hydrogen 2.944 N/A LYS 212.A N VAL 208.A O no hydrogen 3.050 N/A LYS 212.A NZ GLU 255.A OE1 no hydrogen 3.091 N/A LYS 212.A NZ ASP 259.A OD2 no hydrogen 2.593 N/A ASP 213.A N LYS 209.A O no hydrogen 2.832 N/A THR 214.A N SER 210.A O no hydrogen 3.097 N/A THR 214.A OG1 SER 210.A O no hydrogen 3.399 N/A MET 215.A N ILE 211.A O no hydrogen 2.909 N/A ASP 216.A N LYS 212.A O no hydrogen 2.768 N/A GLU 217.A N ASP 213.A O no hydrogen 3.175 N/A THR 218.A N THR 214.A O no hydrogen 3.136 N/A THR 218.A OG1 THR 214.A O no hydrogen 2.945 N/A MET 219.A N MET 215.A O no hydrogen 2.919 N/A ASN 220.A N ASP 216.A O no hydrogen 3.171 N/A ASN 221.A N THR 218.A O no hydrogen 3.117 N/A ASN 221.A ND2 ASP 224.A OD2 no hydrogen 2.916 N/A ASN 221.A ND2 TYR 229.A OH no hydrogen 3.031 N/A SER 222.A OG GLU 223.A OE1 no hydrogen 2.581 N/A SER 222.A OG GLU 223.A OE2 no hydrogen 3.173 N/A ASN 226.A ND2 ASN 191.A O no hydrogen 3.414 N/A HIS 227.A NE2 THR 195.A OG1 no hydrogen 2.861 N/A LEU 228.A N ASN 193.A O no hydrogen 2.592 N/A ILE 230.A N THR 195.A O no hydrogen 2.857 N/A ASN 231.A N TRP 270.A O no hydrogen 2.857 N/A ASN 231.A ND2 ILE 211.A O no hydrogen 3.145 N/A PHE 232.A N GLN 197.A O no hydrogen 3.082 N/A THR 233.A N ILE 272.A O no hydrogen 2.941 N/A THR 233.A OG1 ILE 272.A O no hydrogen 3.399 N/A SER 236.A N TYR 200.A O no hydrogen 2.843 N/A SER 236.A OG TYR 200.A O no hydrogen 2.826 N/A SER 237.A OG VAL 46.A O no hydrogen 2.559 N/A GLY 238.A N ASN 243.A O no hydrogen 2.862 N/A GLY 239.A N SER 237.A OG no hydrogen 2.966 N/A THR 240.A N ASN 243.A OD1 no hydrogen 2.838 N/A TRP 242.A N THR 240.A OG1 no hydrogen 3.055 N/A ASN 243.A N THR 240.A O no hydrogen 3.367 N/A SER 244.A OG SER 247.A OG no hydrogen 3.243 N/A SER 247.A N SER 244.A OG no hydrogen 3.261 N/A SER 247.A OG SER 244.A O no hydrogen 2.798 N/A SER 247.A OG SER 244.A OG no hydrogen 3.243 N/A SER 248.A N SER 244.A O no hydrogen 2.886 N/A ALA 249.A N PRO 245.A O no hydrogen 2.836 N/A SER 250.A N SER 246.A O no hydrogen 3.065 N/A SER 250.A OG SER 247.A O no hydrogen 2.639 N/A SER 251.A N SER 248.A O no hydrogen 3.199 N/A SER 251.A OG TYR 204.A OH no hydrogen 2.831 N/A SER 251.A OG SER 248.A O no hydrogen 3.159 N/A ILE 252.A N SER 248.A O no hydrogen 2.954 N/A ASN 253.A N ALA 249.A O no hydrogen 3.002 N/A ASN 253.A ND2 ASP 274.A O no hydrogen 3.046 N/A GLU 255.A N SER 251.A O no hydrogen 3.440 N/A ILE 256.A N ILE 252.A O no hydrogen 3.001 N/A ALA 257.A N ASN 253.A O no hydrogen 2.919 N/A ASN 258.A N PRO 254.A O no hydrogen 2.921 N/A ASP 259.A N GLU 255.A O no hydrogen 3.221 N/A ILE 260.A N ILE 256.A O no hydrogen 3.242 N/A LYS 261.A N ALA 257.A O no hydrogen 2.951 N/A GLN 262.A N ASN 258.A O no hydrogen 2.941 N/A LYS 263.A N ASP 259.A O no hydrogen 2.993 N/A ASN 264.A N ILE 260.A O no hydrogen 2.762 N/A ARG 267.A NH1 HIS 227.A O no hydrogen 3.290 N/A ARG 267.A NH2 ASN 221.A O no hydrogen 2.822 N/A ARG 267.A NH2 ASP 224.A O no hydrogen 2.728 N/A VAL 268.A N SER 27.A OG no hydrogen 2.921 N/A TRP 270.A N TYR 229.A O no hydrogen 2.856 N/A TRP 270.A NE1 LEU 23.A O no hydrogen 3.063 N/A VAL 271.A N ILE 28.A O no hydrogen 2.961 N/A ILE 272.A N ASN 231.A O no hydrogen 2.994 N/A GLN 273.A N GLY 30.A O no hydrogen 2.831 N/A TYR 275.A N THR 50.A O no hydrogen 2.676 N/A TYR 275.A OH MET 49.A O no hydrogen 3.272 N/A ILE 276.A N GLN 51.A OE1 no hydrogen 3.177 N/A LYS 279.A N ASN 277.A OD1 no hydrogen 2.960 N/A TYR 285.A OH ASN 277.A O no hydrogen 2.764 N/A GLU 287.A N LEU 283.A O no hydrogen 3.278 N/A VAL 288.A N LEU 284.A O no hydrogen 3.000 N/A ILE 289.A N TYR 285.A O no hydrogen 3.129 N/A ARG 290.A N GLN 286.A O no hydrogen 3.004 N/A ARG 290.A NE GLU 8.A OE2 no hydrogen 2.910 N/A ARG 290.A NH1 GLU 287.A OE2 no hydrogen 2.787 N/A ARG 290.A NH2 GLU 8.A OE1 no hydrogen 2.967 N/A ALA 291.A N GLU 287.A O no hydrogen 3.125 N/A ALA 291.A N VAL 288.A O no hydrogen 3.276 N/A ASN 292.A N ILE 289.A O no hydrogen 3.213 N/A ASN 292.A ND2 SER 27.A O no hydrogen 3.047 N/A ASN 292.A ND2 ILE 289.A O no hydrogen 3.023 N/A LYS 293.A N ARG 290.A O no hydrogen 3.286 N/A LYS 293.A NZ ASN 264.A OD1 no hydrogen 2.664 N/A LEU 295.A N ASN 292.A O no hydrogen 3.048 N/A