Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3ffb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 7.A N ASP 4.A OD2 no hydrogen 2.989 N/A VAL 8.A N ASP 4.A O no hydrogen 3.161 N/A GLU 9.A N LYS 5.A O no hydrogen 2.803 N/A ARG 10.A N ALA 6.A O no hydrogen 2.810 N/A ARG 10.A NH1 LYS 187.A O no hydrogen 3.225 N/A ARG 10.A NH2 LYS 187.A O no hydrogen 2.412 N/A SER 11.A N ALA 7.A O no hydrogen 3.116 N/A SER 11.A N VAL 8.A O no hydrogen 3.171 N/A SER 11.A OG ALA 7.A O no hydrogen 2.613 N/A LYS 12.A N GLU 9.A O no hydrogen 3.285 N/A LYS 12.A NZ GLU 9.A OE1 no hydrogen 3.420 N/A LYS 12.A NZ GLU 9.A OE2 no hydrogen 3.156 N/A MET 13.A N ARG 10.A O no hydrogen 3.169 N/A ARG 16.A NH1 GLY 22.A O no hydrogen 2.975 N/A ARG 16.A NH1 ALA 25.A O no hydrogen 2.894 N/A ASN 17.A N ILE 14.A O no hydrogen 3.035 N/A ASN 17.A ND2 ILE 14.A O no hydrogen 3.068 N/A LEU 18.A N ASP 15.A O no hydrogen 3.138 N/A ARG 19.A N ARG 16.A O no hydrogen 3.148 N/A LYS 24.A N ASP 21.A O no hydrogen 2.960 N/A ALA 25.A N GLY 22.A O no hydrogen 3.133 N/A ALA 26.A N PHE 327.A O no hydrogen 3.409 N/A ARG 27.A NH1 ASP 15.A OD1 no hydrogen 3.568 N/A ARG 27.A NH1 ASP 15.A OD2 no hydrogen 2.915 N/A ARG 27.A NH1 CYS 324.A O no hydrogen 3.011 N/A ARG 27.A NH2 ASP 15.A OD1 no hydrogen 2.974 N/A GLU 28.A N GLY 325.A O no hydrogen 3.023 N/A VAL 29.A N HIS 190.A O no hydrogen 3.133 N/A LYS 30.A N THR 199.A OG1 no hydrogen 3.234 N/A LEU 31.A N LYS 192.A O no hydrogen 2.951 N/A LEU 32.A N ALA 200.A O no hydrogen 3.003 N/A LEU 33.A N PHE 194.A O no hydrogen 2.773 N/A LEU 34.A N ILE 202.A O no hydrogen 2.827 N/A SER 39.A N ALA 36.A O no hydrogen 3.346 N/A SER 39.A OG ALA 36.A O no hydrogen 2.824 N/A SER 39.A OG CYS 204.A O no hydrogen 3.338 N/A LYS 41.A NZ GLY 35.A O no hydrogen 2.694 N/A ILE 44.A N GLY 40.A O no hydrogen 2.990 N/A VAL 45.A N LYS 41.A O no hydrogen 3.114 N/A LYS 46.A N SER 42.A O no hydrogen 3.038 N/A LYS 46.A NZ VAL 169.A O no hydrogen 3.567 N/A LYS 46.A NZ LEU 170.A O no hydrogen 2.820 N/A GLN 47.A N THR 43.A O no hydrogen 2.828 N/A GLN 47.A NE2 ALA 299.A O no hydrogen 2.804 N/A MET 48.A N ILE 44.A O no hydrogen 3.052 N/A LYS 49.A N VAL 45.A O no hydrogen 3.317 N/A ILE 50.A N LYS 46.A O no hydrogen 2.991 N/A ILE 51.A N GLN 47.A O no hydrogen 2.744 N/A HIS 52.A N MET 48.A O no hydrogen 3.066 N/A GLU 53.A N LYS 49.A O no hydrogen 3.094 N/A GLY 55.A N LYS 49.A O no hydrogen 3.018 N/A SER 57.A N GLU 60.A OE2 no hydrogen 2.526 N/A SER 57.A OG GLU 60.A OE2 no hydrogen 3.204 N/A GLU 60.A N SER 57.A OG no hydrogen 3.333 N/A CYS 61.A N SER 57.A O no hydrogen 2.935 N/A CYS 61.A SG TYR 56.A O no hydrogen 4.026 N/A CYS 61.A SG SER 57.A O no hydrogen 3.433 N/A LYS 62.A N GLU 58.A O no hydrogen 2.815 N/A GLN 63.A N GLU 59.A O no hydrogen 3.387 N/A TYR 64.A N CYS 61.A O no hydrogen 2.903 N/A LYS 65.A N LYS 62.A O no hydrogen 3.331 N/A LYS 65.A NZ TYR 162.A O no hydrogen 3.472 N/A VAL 68.A N TYR 64.A O no hydrogen 2.952 N/A TYR 69.A N LYS 65.A O no hydrogen 3.112 N/A TYR 69.A OH ILE 157.A O no hydrogen 3.328 N/A SER 70.A N ALA 66.A O no hydrogen 2.804 N/A ASN 71.A N VAL 67.A O no hydrogen 2.868 N/A ASN 71.A ND2 ARG 173.A O no hydrogen 3.475 N/A THR 72.A N VAL 68.A O no hydrogen 3.017 N/A THR 72.A OG1 VAL 68.A O no hydrogen 2.779 N/A ILE 73.A N TYR 69.A O no hydrogen 2.825 N/A GLN 74.A N SER 70.A O no hydrogen 2.885 N/A SER 75.A N ASN 71.A O no hydrogen 2.990 N/A SER 75.A OG ASN 71.A O no hydrogen 2.706 N/A ILE 76.A N THR 72.A O no hydrogen 3.126 N/A ILE 77.A N ILE 73.A O no hydrogen 3.138 N/A ALA 78.A N GLN 74.A O no hydrogen 2.908 N/A ILE 79.A N SER 75.A O no hydrogen 3.104 N/A ILE 80.A N ILE 76.A O no hydrogen 2.804 N/A ARG 81.A N ILE 77.A O no hydrogen 2.823 N/A ALA 82.A N ALA 78.A O no hydrogen 3.108 N/A MET 83.A N ILE 79.A O no hydrogen 3.133 N/A GLY 84.A N ARG 81.A O no hydrogen 3.086 N/A ARG 85.A N ARG 81.A O no hydrogen 3.485 N/A LEU 86.A N ALA 82.A O no hydrogen 2.771 N/A ILE 88.A N MET 83.A O no hydrogen 2.910 N/A GLY 91.A N ASP 128.A OD2 no hydrogen 2.711 N/A ASP 92.A N ASP 128.A OD1 no hydrogen 2.981 N/A ALA 94.A N ASP 92.A OD1 no hydrogen 3.359 N/A ARG 95.A N ASP 92.A O no hydrogen 2.913 N/A ARG 95.A NE ASP 98.A OD2 no hydrogen 2.812 N/A ARG 95.A NH1 ASP 92.A OD2 no hydrogen 3.361 N/A ARG 95.A NH2 ASP 98.A OD2 no hydrogen 2.984 N/A ASP 97.A N ALA 94.A O no hydrogen 3.263 N/A ALA 99.A N ARG 95.A O no hydrogen 2.716 N/A ARG 100.A N ALA 96.A O no hydrogen 3.001 N/A GLN 101.A N ASP 97.A O no hydrogen 2.902 N/A GLN 101.A NE2 GLU 117.A OE2 no hydrogen 2.934 N/A LEU 102.A N ASP 98.A O no hydrogen 2.844 N/A PHE 103.A N ALA 99.A O no hydrogen 3.311 N/A VAL 104.A N ARG 100.A O no hydrogen 3.111 N/A LEU 105.A N GLN 101.A O no hydrogen 2.832 N/A ALA 106.A N LEU 102.A O no hydrogen 2.904 N/A GLY 107.A N PHE 103.A O no hydrogen 2.829 N/A ALA 108.A N LEU 105.A O no hydrogen 3.468 N/A LEU 118.A N THR 115.A OG1 no hydrogen 3.020 N/A ALA 119.A N THR 115.A O no hydrogen 2.911 N/A GLY 120.A N ALA 116.A O no hydrogen 2.906 N/A VAL 121.A N GLU 117.A O no hydrogen 2.991 N/A ILE 122.A N LEU 118.A O no hydrogen 2.984 N/A LYS 123.A N ALA 119.A O no hydrogen 2.793 N/A LYS 123.A NZ ASP 155.A OD1 no hydrogen 3.097 N/A ARG 124.A N GLY 120.A O no hydrogen 3.104 N/A ARG 124.A NE ASP 98.A OD1 no hydrogen 3.406 N/A ARG 124.A NE ASP 98.A OD2 no hydrogen 2.879 N/A ARG 124.A NH2 ASP 98.A OD1 no hydrogen 2.889 N/A LEU 125.A N VAL 121.A O no hydrogen 3.199 N/A TRP 126.A N ILE 122.A O no hydrogen 2.797 N/A TRP 126.A NE1 ASN 152.A OD1 no hydrogen 2.814 N/A LYS 127.A N LYS 123.A O no hydrogen 2.746 N/A ASP 128.A N LEU 125.A O no hydrogen 2.921 N/A GLY 130.A N ASP 128.A OD2 no hydrogen 2.960 N/A VAL 131.A N ASP 128.A OD2 no hydrogen 3.333 N/A GLN 132.A N ASP 128.A O no hydrogen 3.011 N/A GLN 132.A NE2 TRP 126.A O no hydrogen 2.860 N/A ALA 133.A N SER 129.A O no hydrogen 2.995 N/A CYS 134.A N GLY 130.A O no hydrogen 3.068 N/A CYS 134.A SG ILE 79.A O no hydrogen 3.514 N/A CYS 134.A SG TYR 141.A OH no hydrogen 3.774 N/A PHE 135.A N VAL 131.A O no hydrogen 2.894 N/A ASN 136.A N GLN 132.A O no hydrogen 2.900 N/A ARG 137.A N CYS 134.A O no hydrogen 2.885 N/A ARG 137.A NE GLU 140.A OE2 no hydrogen 2.776 N/A ARG 137.A NH2 GLU 140.A OE1 no hydrogen 2.792 N/A ARG 137.A NH2 GLU 140.A OE2 no hydrogen 3.146 N/A SER 138.A N PHE 135.A O no hydrogen 3.240 N/A SER 138.A OG PHE 135.A O no hydrogen 3.226 N/A ARG 139.A NE ASP 211.A O no hydrogen 2.798 N/A ARG 139.A NH2 ASP 211.A O no hydrogen 3.466 N/A GLU 140.A N ARG 137.A O no hydrogen 2.956 N/A TYR 141.A N SER 138.A O no hydrogen 2.888 N/A TYR 141.A OH CYS 134.A O no hydrogen 2.933 N/A SER 146.A OG ARG 171.A O no hydrogen 2.569 N/A TYR 149.A OH ASP 168.A OD1 no hydrogen 2.529 N/A TYR 150.A N SER 146.A O no hydrogen 3.182 N/A TYR 150.A OH ASP 168.A O no hydrogen 2.798 N/A LEU 151.A N ALA 147.A O no hydrogen 3.002 N/A ASN 152.A N ALA 148.A O no hydrogen 2.879 N/A ASP 153.A N TYR 150.A O no hydrogen 3.101 N/A ARG 156.A NE ASP 153.A OD2 no hydrogen 3.336 N/A ARG 156.A NH1 ASP 168.A OD2 no hydrogen 2.709 N/A ARG 156.A NH2 ASP 153.A OD2 no hydrogen 2.711 N/A ARG 156.A NH2 ASP 168.A OD1 no hydrogen 2.946 N/A ARG 156.A NH2 ASP 168.A OD2 no hydrogen 3.502 N/A ILE 157.A N ASP 153.A O no hydrogen 3.019 N/A ALA 158.A N LEU 154.A O no hydrogen 2.815 N/A GLN 159.A N ARG 156.A O no hydrogen 3.341 N/A GLN 159.A NE2 ASP 155.A O no hydrogen 2.752 N/A TYR 162.A N GLN 159.A O no hydrogen 3.120 N/A TYR 162.A OH ASP 168.A OD2 no hydrogen 2.899 N/A THR 165.A N ASP 168.A OD2 no hydrogen 3.159 N/A GLN 167.A NE2 THR 300.A O no hydrogen 3.616 N/A ASP 168.A N THR 165.A OG1 no hydrogen 3.181 N/A VAL 169.A N THR 165.A O no hydrogen 3.151 N/A LEU 170.A N GLN 166.A O no hydrogen 2.877 N/A ARG 171.A N GLN 167.A O no hydrogen 3.099 N/A ARG 171.A N ASP 168.A O no hydrogen 3.220 N/A THR 172.A N VAL 169.A O no hydrogen 3.140 N/A THR 172.A OG1 VAL 169.A O no hydrogen 2.591 N/A ARG 173.A N ASN 71.A OD1 no hydrogen 2.967 N/A ARG 173.A NH1 GLN 74.A OE1 no hydrogen 2.742 N/A ARG 173.A NH2 GLN 74.A OE1 no hydrogen 2.652 N/A VAL 180.A N ASP 195.A O no hydrogen 3.258 N/A THR 182.A N MET 193.A O no hydrogen 2.798 N/A HIS 183.A NE2 GLU 181.A OE2 no hydrogen 2.603 N/A PHE 184.A N PHE 191.A O no hydrogen 3.098 N/A THR 185.A N GLU 53.A OE1 no hydrogen 2.983 N/A PHE 186.A N LEU 189.A O no hydrogen 3.013 N/A LYS 187.A NZ ASP 310.A O no hydrogen 3.276 N/A LYS 187.A NZ ASP 310.A OD2 no hydrogen 3.116 N/A LYS 187.A NZ ASP 314.A OD1 no hydrogen 2.600 N/A LEU 189.A N PHE 186.A O no hydrogen 2.875 N/A HIS 190.A N ARG 27.A O no hydrogen 2.806 N/A PHE 191.A N PHE 184.A O no hydrogen 2.751 N/A LYS 192.A N VAL 29.A O no hydrogen 2.915 N/A MET 193.A N THR 182.A O no hydrogen 2.697 N/A PHE 194.A N LEU 31.A O no hydrogen 2.840 N/A ASP 195.A N VAL 180.A O no hydrogen 2.644 N/A THR 199.A OG1 LYS 30.A O no hydrogen 3.454 N/A ALA 200.A N LYS 30.A O no hydrogen 3.315 N/A ILE 201.A N SER 236.A O no hydrogen 2.856 N/A ILE 202.A N LEU 32.A O no hydrogen 2.930 N/A PHE 203.A N ILE 238.A O no hydrogen 2.825 N/A CYS 204.A N LEU 34.A O no hydrogen 2.765 N/A VAL 205.A N PHE 240.A O no hydrogen 2.944 N/A LEU 207.A N ASN 242.A O no hydrogen 3.049 N/A ASP 209.A N ALA 206.A O no hydrogen 3.100 N/A TYR 210.A N LEU 207.A O no hydrogen 3.261 N/A TYR 210.A OH SER 254.A O no hydrogen 2.669 N/A LEU 212.A N ASP 209.A O no hydrogen 3.204 N/A ASN 214.A ND2 CYS 259.A O no hydrogen 3.696 N/A HIS 217.A N ASN 214.A OD1 no hydrogen 2.785 N/A HIS 217.A ND1 ASN 214.A OD1 no hydrogen 2.733 N/A GLU 218.A N ASN 214.A O no hydrogen 3.061 N/A SER 219.A N ARG 215.A O no hydrogen 2.904 N/A MET 220.A N MET 216.A O no hydrogen 2.896 N/A LYS 221.A N HIS 217.A O no hydrogen 2.991 N/A LEU 222.A N GLU 218.A O no hydrogen 3.080 N/A PHE 223.A N SER 219.A O no hydrogen 2.967 N/A ASP 224.A N MET 220.A O no hydrogen 2.902 N/A SER 225.A N LYS 221.A O no hydrogen 3.144 N/A ILE 226.A N LEU 222.A O no hydrogen 3.011 N/A CYS 227.A N PHE 223.A O no hydrogen 2.705 N/A ASN 228.A N ASP 224.A O no hydrogen 3.135 N/A ASN 228.A ND2 ASP 224.A O no hydrogen 2.890 N/A ASN 228.A ND2 LEU 283.A O no hydrogen 2.592 N/A ASN 229.A N ILE 226.A O no hydrogen 3.251 N/A TRP 231.A N ASN 229.A OD1 no hydrogen 2.656 N/A PHE 232.A N ASN 229.A O no hydrogen 3.190 N/A THR 233.A N LYS 230.A O no hydrogen 3.194 N/A THR 233.A OG1 LYS 230.A O no hydrogen 2.628 N/A THR 235.A N PHE 232.A O no hydrogen 2.847 N/A THR 235.A OG1 VAL 198.A O no hydrogen 2.779 N/A SER 236.A N THR 199.A O no hydrogen 3.156 N/A SER 236.A OG ASN 320.A OD1 no hydrogen 2.680 N/A ILE 238.A N ILE 201.A O no hydrogen 2.813 N/A LEU 239.A N TYR 293.A O no hydrogen 2.821 N/A PHE 240.A N PHE 203.A O no hydrogen 2.884 N/A LEU 241.A N HIS 295.A O no hydrogen 2.803 N/A ASN 242.A N VAL 205.A O no hydrogen 2.769 N/A ASN 242.A ND2 SER 39.A O no hydrogen 2.802 N/A LYS 243.A NZ GLU 38.A O no hydrogen 2.798 N/A LYS 243.A NZ ASP 145.A OD2 no hydrogen 2.664 N/A LYS 244.A N THR 297.A O no hydrogen 3.135 N/A PHE 247.A N LYS 243.A O no hydrogen 2.959 N/A GLU 248.A N LYS 244.A O no hydrogen 2.777 N/A GLU 249.A N ASP 245.A O no hydrogen 3.330 N/A LYS 250.A N LEU 246.A O no hydrogen 2.976 N/A LYS 250.A NZ SER 208.A O no hydrogen 2.702 N/A LYS 250.A NZ ASP 211.A OD1 no hydrogen 2.354 N/A ILE 251.A N PHE 247.A O no hydrogen 3.052 N/A LYS 252.A NZ GLU 249.A OE2 no hydrogen 3.376 N/A LYS 253.A N LYS 250.A O no hydrogen 3.088 N/A SER 254.A OG ASP 211.A OD2 no hydrogen 3.020 N/A LEU 256.A N ASN 267.A OD1 no hydrogen 3.115 N/A ILE 258.A N PRO 255.A O no hydrogen 3.160 N/A CYS 259.A N LEU 256.A O no hydrogen 2.864 N/A CYS 259.A SG ASN 214.A OD1 no hydrogen 3.646 N/A TYR 260.A N LEU 256.A O no hydrogen 2.819 N/A GLU 262.A N GLU 262.A OE1 no hydrogen 2.704 N/A TYR 263.A N TYR 260.A O no hydrogen 2.900 N/A TYR 263.A OH SER 266.A O no hydrogen 2.607 N/A SER 266.A N GLU 271.A OE1 no hydrogen 2.844 N/A SER 266.A OG GLU 271.A OE2 no hydrogen 3.169 N/A GLU 270.A N GLU 270.A OE1 no hydrogen 2.660 N/A GLU 271.A N THR 268.A OG1 no hydrogen 3.407 N/A ALA 272.A N THR 268.A O no hydrogen 2.911 N/A ALA 273.A N TYR 269.A O no hydrogen 2.975 N/A ALA 274.A N GLU 270.A O no hydrogen 3.261 N/A TYR 275.A N GLU 271.A O no hydrogen 3.031 N/A TYR 275.A OH GLU 262.A OE2 no hydrogen 2.428 N/A ILE 276.A N ALA 272.A O no hydrogen 3.072 N/A GLN 277.A N ALA 273.A O no hydrogen 3.000 N/A GLN 277.A NE2 GLU 281.A OE2 no hydrogen 2.872 N/A CYS 278.A N ALA 274.A O no hydrogen 2.909 N/A CYS 278.A SG ALA 274.A O no hydrogen 3.538 N/A GLN 279.A N TYR 275.A O no hydrogen 2.840 N/A PHE 280.A N ILE 276.A O no hydrogen 3.132 N/A GLU 281.A N GLN 277.A O no hydrogen 2.988 N/A ASP 282.A N CYS 278.A O no hydrogen 3.064 N/A LEU 283.A N PHE 280.A O no hydrogen 3.030 N/A ASN 284.A N GLU 281.A O no hydrogen 3.270 N/A ASN 284.A ND2 LYS 290.A O no hydrogen 2.878 N/A LYS 285.A N ASN 228.A OD1 no hydrogen 2.817 N/A ARG 286.A N ASN 284.A OD1 no hydrogen 3.092 N/A LYS 287.A NZ ASP 282.A O no hydrogen 3.312 N/A LYS 287.A NZ ASP 282.A OD1 no hydrogen 2.962 N/A LYS 287.A NZ ASN 284.A O no hydrogen 2.816 N/A THR 289.A N ARG 286.A O no hydrogen 2.834 N/A THR 289.A OG1 ASP 288.A OD1 no hydrogen 3.067 N/A LYS 290.A N ARG 286.A O no hydrogen 2.552 N/A LYS 290.A NZ PHE 232.A O no hydrogen 2.975 N/A LYS 290.A NZ THR 233.A O no hydrogen 2.796 N/A LYS 290.A NZ THR 235.A O no hydrogen 2.572 N/A TYR 293.A N ILE 237.A O no hydrogen 2.938 N/A THR 294.A OG1 GLU 281.A OE2 no hydrogen 2.653 N/A HIS 295.A N LEU 239.A O no hydrogen 2.818 N/A THR 297.A N LEU 241.A O no hydrogen 2.840 N/A THR 297.A OG1 ASN 242.A OD1 no hydrogen 2.821 N/A CYS 298.A N ASN 304.A OD1 no hydrogen 2.741 N/A CYS 298.A SG THR 300.A OG1 no hydrogen 3.635 N/A ALA 299.A N ASN 242.A OD1 no hydrogen 2.984 N/A ASP 301.A N CYS 298.A O no hydrogen 2.883 N/A ASN 304.A N ASP 301.A OD1 no hydrogen 3.411 N/A VAL 305.A N ASP 301.A O no hydrogen 2.967 N/A GLN 306.A N ALA 302.A O no hydrogen 2.920 N/A PHE 307.A N LYS 303.A O no hydrogen 3.186 N/A VAL 308.A N ASN 304.A O no hydrogen 2.891 N/A PHE 309.A N VAL 305.A O no hydrogen 2.751 N/A ASP 310.A N GLN 306.A O no hydrogen 2.877 N/A ALA 311.A N PHE 307.A O no hydrogen 3.185 N/A VAL 312.A N VAL 308.A O no hydrogen 2.826 N/A THR 313.A N PHE 309.A O no hydrogen 2.891 N/A THR 313.A OG1 PHE 309.A O no hydrogen 3.002 N/A ASP 314.A N ASP 310.A O no hydrogen 3.199 N/A VAL 315.A N ALA 311.A O no hydrogen 3.246 N/A ILE 316.A N VAL 312.A O no hydrogen 3.189 N/A ILE 317.A N THR 313.A O no hydrogen 2.825 N/A LYS 318.A N ASP 314.A O no hydrogen 2.994 N/A ASN 319.A N VAL 315.A O no hydrogen 2.893 N/A ASN 319.A N ILE 316.A O no hydrogen 3.061 N/A ASN 320.A N ILE 316.A O no hydrogen 2.695 N/A ASP 323.A N ASN 320.A O no hydrogen 2.774 N/A CYS 324.A N LEU 321.A O no hydrogen 3.075 N/A CYS 324.A SG ASN 320.A O no hydrogen 3.558 N/A PHE 327.A N ALA 26.A O no hydrogen 3.005 N/A