Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3ffc_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 3.A N VAL 103.A O no hydrogen 3.103 N/A HIS 3.A ND1 ASP 29.A OD2 no hydrogen 2.694 N/A HIS 3.A NE2 GLU 180.A OE1 no hydrogen 2.966 N/A SER 4.A N ASP 29.A OD1 no hydrogen 2.916 N/A MET 5.A N CYS 101.A O no hydrogen 2.951 N/A ARG 6.A N TYR 27.A O no hydrogen 2.861 N/A ARG 6.A NH1 MET 5.A O no hydrogen 3.229 N/A ARG 6.A NH1 ASP 102.A OD1 no hydrogen 3.175 N/A ARG 6.A NH2 ASP 102.A OD1 no hydrogen 3.330 N/A TYR 7.A N TYR 99.A O no hydrogen 2.626 N/A PHE 8.A N VAL 25.A O no hydrogen 2.842 N/A ASP 9.A N SER 97.A O no hydrogen 2.867 N/A THR 10.A N ILE 23.A O no hydrogen 2.905 N/A ALA 11.A N LEU 95.A O no hydrogen 2.856 N/A MET 12.A N ARG 21.A O no hydrogen 2.914 N/A SER 13.A N HIS 93.A O no hydrogen 2.878 N/A SER 13.A OG HIS 93.A O no hydrogen 3.499 N/A ARG 14.A NE GLU 19.A O no hydrogen 2.791 N/A ARG 14.A NH2 GLU 19.A O no hydrogen 2.884 N/A ARG 14.A NH2 ASP 39.A OD1 no hydrogen 3.476 N/A ARG 17.A N ARG 14.A O no hydrogen 2.878 N/A GLY 18.A N ARG 14.A O no hydrogen 3.287 N/A ARG 21.A N MET 12.A O no hydrogen 2.832 N/A ARG 21.A NE ASP 37.A OD1 no hydrogen 2.780 N/A ARG 21.A NH2 ASP 37.A OD1 no hydrogen 3.446 N/A ARG 21.A NH2 ASP 37.A OD2 no hydrogen 2.619 N/A PHE 22.A N SER 38.A OG no hydrogen 3.168 N/A ILE 23.A N THR 10.A O no hydrogen 2.959 N/A SER 24.A N PHE 36.A O no hydrogen 2.602 N/A SER 24.A OG ASP 9.A OD1 no hydrogen 2.664 N/A VAL 25.A N PHE 8.A O no hydrogen 3.094 N/A GLY 26.A N VAL 34.A O no hydrogen 2.641 N/A TYR 27.A N ARG 6.A O no hydrogen 2.806 N/A VAL 28.A N THR 31.A O no hydrogen 3.049 N/A ASP 29.A N SER 4.A O no hydrogen 2.629 N/A ASP 30.A N TYR 209.A OH no hydrogen 3.277 N/A THR 31.A N VAL 28.A O no hydrogen 2.972 N/A THR 31.A OG1 TYR 209.A OH no hydrogen 2.600 N/A PHE 33.A N GLY 26.A O no hydrogen 2.857 N/A VAL 34.A N GLY 26.A O no hydrogen 3.482 N/A ARG 35.A NH1 ASP 37.A OD2 no hydrogen 2.916 N/A PHE 36.A N SER 24.A O no hydrogen 2.758 N/A SER 38.A N PHE 22.A O no hydrogen 2.534 N/A SER 38.A OG PRO 20.A O no hydrogen 3.461 N/A ASP 39.A N ASP 37.A OD1 no hydrogen 3.095 N/A ALA 49.A N PHE 33.A O no hydrogen 2.990 N/A ILE 52.A N ALA 49.A O no hydrogen 2.988 N/A GLU 53.A N ALA 49.A O no hydrogen 3.185 N/A GLN 54.A N PRO 50.A O no hydrogen 3.220 N/A GLN 54.A NE2 ASN 174.A O no hydrogen 3.631 N/A GLU 55.A N ILE 52.A O no hydrogen 2.912 N/A GLU 58.A N GLU 58.A OE1 no hydrogen 2.907 N/A TYR 59.A OH TYR 171.A OH no hydrogen 2.420 N/A ASP 61.A N PRO 57.A O no hydrogen 2.791 N/A ARG 62.A N GLU 58.A O no hydrogen 2.948 N/A ARG 62.A NH1 GLN 65.A OE1 no hydrogen 2.685 N/A ASN 63.A N TYR 59.A O no hydrogen 2.974 N/A ASN 63.A ND2 TYR 59.A O no hydrogen 2.503 N/A THR 64.A N TRP 60.A O no hydrogen 3.077 N/A THR 64.A OG1 TRP 60.A O no hydrogen 2.719 N/A GLN 65.A N ASP 61.A O no hydrogen 2.892 N/A ILE 66.A N ARG 62.A O no hydrogen 2.997 N/A PHE 67.A N ASN 63.A O no hydrogen 2.889 N/A LYS 68.A N THR 64.A O no hydrogen 2.929 N/A THR 69.A N GLN 65.A O no hydrogen 2.940 N/A ASN 70.A N ILE 66.A O no hydrogen 2.714 N/A THR 71.A N PHE 67.A O no hydrogen 2.875 N/A THR 71.A OG1 LYS 68.A O no hydrogen 2.631 N/A GLN 72.A N LYS 68.A O no hydrogen 3.316 N/A THR 73.A N THR 69.A O no hydrogen 3.331 N/A ASP 74.A N ASN 70.A O no hydrogen 2.856 N/A ARG 75.A N THR 71.A O no hydrogen 2.829 N/A GLU 76.A N GLN 72.A O no hydrogen 3.332 N/A SER 77.A N THR 73.A O no hydrogen 2.796 N/A SER 77.A OG THR 73.A O no hydrogen 3.526 N/A LEU 78.A N ASP 74.A O no hydrogen 2.844 N/A ARG 79.A N.A ARG 75.A O no hydrogen 3.056 N/A ARG 79.A N.B ARG 75.A O no hydrogen 3.050 N/A ASN 80.A N GLU 76.A O no hydrogen 2.976 N/A LEU 81.A N SER 77.A O no hydrogen 2.807 N/A ARG 82.A N LEU 78.A O no hydrogen 3.178 N/A ARG 82.A NH1 GLN 87.A O no hydrogen 3.558 N/A GLY 83.A N ARG 79.A O.A no hydrogen 3.224 N/A GLY 83.A N ARG 79.A O.B no hydrogen 3.242 N/A TYR 84.A N ASN 80.A O no hydrogen 2.897 N/A TYR 85.A N LEU 81.A O no hydrogen 3.096 N/A TYR 85.A OH ASP 137.A OD2 no hydrogen 2.505 N/A ASN 86.A N GLY 83.A O no hydrogen 3.447 N/A GLN 87.A N ARG 82.A O no hydrogen 2.817 N/A SER 92.A OG SER 13.A O no hydrogen 2.527 N/A HIS 93.A N SER 13.A OG no hydrogen 3.057 N/A HIS 93.A ND1 ASP 119.A OD2 no hydrogen 2.860 N/A THR 94.A N ASP 119.A OD1 no hydrogen 2.940 N/A LEU 95.A N ALA 11.A O no hydrogen 2.770 N/A GLN 96.A N ALA 117.A O no hydrogen 2.841 N/A SER 97.A N ASP 9.A O no hydrogen 2.986 N/A MET 98.A N GLN 115.A O no hydrogen 2.977 N/A TYR 99.A N TYR 7.A O no hydrogen 3.008 N/A GLY 100.A N HIS 113.A O no hydrogen 3.266 N/A CYS 101.A N MET 5.A O no hydrogen 2.940 N/A ASP 102.A N ARG 111.A O no hydrogen 2.763 N/A VAL 103.A N HIS 3.A O no hydrogen 2.805 N/A GLY 104.A N ARG 108.A O no hydrogen 2.768 N/A GLY 107.A N GLY 104.A O no hydrogen 2.927 N/A LEU 110.A N ASP 102.A O no hydrogen 2.642 N/A ARG 111.A N ASP 102.A O no hydrogen 3.294 N/A HIS 113.A N GLY 100.A O no hydrogen 2.798 N/A HIS 113.A NE2 ASP 102.A OD2 no hydrogen 2.800 N/A GLN 115.A N MET 98.A O no hydrogen 2.916 N/A TYR 116.A N ILE 124.A O no hydrogen 2.592 N/A ALA 117.A N GLN 96.A O no hydrogen 2.901 N/A TYR 118.A N LYS 121.A O no hydrogen 2.868 N/A TYR 118.A OH GLN 87.A OE1 no hydrogen 2.668 N/A ASP 119.A N THR 94.A O no hydrogen 2.764 N/A LYS 121.A N TYR 118.A O no hydrogen 3.131 N/A TYR 123.A N TYR 116.A O no hydrogen 2.694 N/A TYR 123.A OH THR 143.A OG1 no hydrogen 2.631 N/A ILE 124.A N TYR 116.A O no hydrogen 3.265 N/A ALA 125.A N THR 134.A O no hydrogen 3.082 N/A LEU 126.A N ASN 114.A O no hydrogen 2.686 N/A ASN 127.A N SER 132.A O no hydrogen 2.671 N/A ASN 127.A ND2 THR 134.A OG1 no hydrogen 2.549 N/A LEU 130.A N ASN 127.A O no hydrogen 2.944 N/A ARG 131.A N ASP 129.A OD1 no hydrogen 2.983 N/A ARG 131.A NH1 ASP 129.A O no hydrogen 3.313 N/A SER 132.A OG ASN 127.A OD1 no hydrogen 3.001 N/A SER 132.A OG ASP 129.A OD1 no hydrogen 2.905 N/A SER 132.A OG ASP 129.A OD2 no hydrogen 3.406 N/A THR 134.A N ALA 125.A O no hydrogen 2.994 N/A ALA 136.A N TYR 123.A O no hydrogen 2.901 N/A ALA 140.A N ASP 137.A OD1 no hydrogen 2.818 N/A GLN 141.A N ASP 137.A O no hydrogen 3.145 N/A GLN 141.A N THR 138.A O no hydrogen 3.090 N/A ILE 142.A N ALA 139.A O no hydrogen 3.021 N/A THR 143.A N ALA 139.A O no hydrogen 3.488 N/A THR 143.A OG1 TYR 123.A OH no hydrogen 2.631 N/A GLN 144.A N ALA 140.A O no hydrogen 2.776 N/A GLN 144.A NE2 GLU 148.A OE1 no hydrogen 3.530 N/A ARG 145.A N GLN 141.A O no hydrogen 2.880 N/A LYS 146.A N ILE 142.A O no hydrogen 2.968 N/A TRP 147.A N THR 143.A O no hydrogen 2.761 N/A GLU 148.A N GLN 144.A O no hydrogen 2.748 N/A ALA 149.A N ARG 145.A O no hydrogen 2.993 N/A ALA 150.A N LYS 146.A O no hydrogen 3.212 N/A ARG 151.A N GLU 148.A O no hydrogen 3.219 N/A ARG 151.A NH1 GLU 154.A OE2 no hydrogen 2.803 N/A VAL 152.A N TRP 147.A O no hydrogen 3.038 N/A ASP 156.A N VAL 152.A O no hydrogen 2.856 N/A ARG 157.A N ALA 153.A O no hydrogen 2.702 N/A ARG 157.A NE LEU 130.A O no hydrogen 3.063 N/A ALA 158.A N GLU 154.A O no hydrogen 3.051 N/A TYR 159.A N GLN 155.A O no hydrogen 3.337 N/A LEU 160.A N ASP 156.A O no hydrogen 2.917 N/A GLU 161.A N ARG 157.A O no hydrogen 2.842 N/A GLY 162.A N ALA 158.A O no hydrogen 2.995 N/A CYS 164.A N TYR 159.A O no hydrogen 2.813 N/A GLU 166.A N GLY 162.A O no hydrogen 2.989 N/A TRP 167.A N THR 163.A O no hydrogen 2.924 N/A LEU 168.A N CYS 164.A O no hydrogen 2.858 N/A ARG 169.A N VAL 165.A O no hydrogen 3.020 N/A ARG 169.A NE GLU 166.A OE1 no hydrogen 3.308 N/A ARG 169.A NH2 GLU 166.A OE1 no hydrogen 2.882 N/A ARG 170.A N GLU 166.A O no hydrogen 3.225 N/A ARG 170.A NH1 GLU 55.A OE1 no hydrogen 2.859 N/A TYR 171.A N TRP 167.A O no hydrogen 2.716 N/A TYR 171.A OH TYR 59.A OH no hydrogen 2.420 N/A LEU 172.A N LEU 168.A O no hydrogen 2.793 N/A GLU 173.A N ARG 169.A O no hydrogen 2.868 N/A ASN 174.A N ARG 170.A O no hydrogen 3.078 N/A GLY 175.A N TYR 171.A O no hydrogen 2.889 N/A LYS 176.A N GLU 173.A O no hydrogen 3.491 N/A THR 178.A N GLY 175.A O no hydrogen 2.788 N/A LEU 179.A N GLY 175.A O no hydrogen 2.739 N/A GLU 180.A N LYS 176.A O no hydrogen 3.027 N/A ARG 181.A NE ASP 183.A OD1 no hydrogen 3.193 N/A ARG 181.A NH1 THR 178.A O no hydrogen 3.016 N/A LYS 186.A N LEU 206.A O no hydrogen 2.850 N/A HIS 188.A N TRP 204.A O no hydrogen 3.308 N/A THR 190.A N ARG 202.A O no hydrogen 2.900 N/A HIS 192.A N THR 200.A O no hydrogen 2.766 N/A ILE 194.A N GLU 198.A O no hydrogen 2.969 N/A SER 195.A N GLU 198.A O no hydrogen 3.074 N/A HIS 197.A N SER 195.A OG no hydrogen 3.178 N/A GLU 198.A N SER 195.A OG no hydrogen 3.166 N/A ALA 199.A N VAL 249.A O no hydrogen 2.894 N/A THR 200.A N HIS 192.A O no hydrogen 2.691 N/A LEU 201.A N VAL 247.A O no hydrogen 2.797 N/A ARG 202.A N THR 190.A O no hydrogen 2.913 N/A CYS 203.A N ALA 245.A O no hydrogen 2.738 N/A TRP 204.A N HIS 188.A O no hydrogen 2.832 N/A TRP 204.A NE1 THR 190.A OG1 no hydrogen 3.010 N/A ALA 205.A N LYS 243.A O no hydrogen 2.913 N/A LEU 206.A N LYS 186.A O no hydrogen 2.944 N/A PHE 208.A N PHE 241.A O no hydrogen 3.117 N/A TYR 209.A N ASP 183.A O no hydrogen 3.058 N/A TYR 209.A OH THR 31.A OG1 no hydrogen 2.600 N/A ALA 211.A N ASP 30.A OD2 no hydrogen 2.734 N/A THR 214.A N GLN 262.A O no hydrogen 3.056 N/A THR 216.A N HIS 260.A O no hydrogen 3.079 N/A TRP 217.A NE1 ALA 245.A O no hydrogen 2.945 N/A GLN 218.A N THR 258.A O no hydrogen 2.635 N/A ARG 219.A N GLU 222.A O no hydrogen 2.576 N/A ASP 220.A N ARG 256.A O no hydrogen 2.742 N/A GLU 222.A N ARG 219.A O no hydrogen 2.873 N/A GLN 224.A N TRP 217.A O no hydrogen 3.228 N/A GLN 224.A NE2 GLU 222.A O no hydrogen 3.455 N/A THR 225.A OG1 GLN 224.A O no hydrogen 2.711 N/A GLU 229.A N ALA 246.A O no hydrogen 2.757 N/A VAL 231.A N TRP 244.A O no hydrogen 3.187 N/A ARG 234.A N GLN 242.A O no hydrogen 2.827 N/A ARG 234.A NE GLN 242.A OE1 no hydrogen 2.916 N/A ARG 234.A NH2 GLN 242.A OE1 no hydrogen 3.112 N/A ALA 236.A N THR 240.A O no hydrogen 2.695 N/A THR 240.A OG1 PHE 208.A O no hydrogen 3.078 N/A PHE 241.A N PHE 208.A O no hydrogen 2.768 N/A GLN 242.A N ARG 234.A O no hydrogen 2.817 N/A LYS 243.A N ALA 205.A O no hydrogen 2.999 N/A LYS 243.A NZ VAL 231.A O no hydrogen 3.238 N/A LYS 243.A NZ THR 233.A OG1 no hydrogen 2.490 N/A ALA 245.A N CYS 203.A O no hydrogen 2.882 N/A ALA 246.A N GLU 229.A O no hydrogen 3.079 N/A VAL 247.A N LEU 201.A O no hydrogen 2.949 N/A VAL 249.A N ALA 199.A O no hydrogen 2.669 N/A SER 251.A N HIS 197.A O no hydrogen 2.486 N/A GLY 252.A N GLU 254.A OE1 no hydrogen 2.578 N/A GLU 253.A N PRO 250.A O no hydrogen 3.139 N/A ARG 256.A N GLU 253.A O no hydrogen 3.326 N/A ARG 256.A NE ASP 220.A OD1 no hydrogen 3.554 N/A ARG 256.A NE ASP 220.A OD2 no hydrogen 3.402 N/A ARG 256.A NH1 GLU 253.A OE1 no hydrogen 3.348 N/A ARG 256.A NH2 ASP 220.A OD2 no hydrogen 2.952 N/A TYR 257.A N GLU 254.A O no hydrogen 2.884 N/A THR 258.A N GLN 218.A O no hydrogen 2.726 N/A THR 258.A OG1 GLN 218.A O no hydrogen 3.172 N/A THR 258.A OG1 HIS 260.A NE2 no hydrogen 2.921 N/A CYS 259.A N LEU 272.A O no hydrogen 2.860 N/A CYS 259.A SG THR 216.A O no hydrogen 3.986 N/A HIS 260.A N THR 216.A O no hydrogen 2.669 N/A HIS 260.A NE2 THR 258.A OG1 no hydrogen 2.921 N/A VAL 261.A N LEU 270.A O no hydrogen 3.205 N/A GLN 262.A N THR 214.A O no hydrogen 3.002 N/A GLN 262.A NE2 HIS 263.A O no hydrogen 3.576 N/A HIS 263.A ND1 GLU 212.A O no hydrogen 3.072 N/A LEU 266.A N HIS 263.A O no hydrogen 3.128 N/A LEU 270.A N VAL 261.A O no hydrogen 3.260 N/A LEU 272.A N CYS 259.A O no hydrogen 2.953 N/A