Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3fme_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 7.A N LYS 4.A O no hydrogen 3.165 N/A GLU 9.A N ARG 26.A O no hydrogen 2.884 N/A ILE 11.A N LYS 24.A O no hydrogen 2.906 N/A MET 12.A N LYS 24.A O no hydrogen 3.353 N/A LEU 14.A N VAL 22.A O no hydrogen 2.878 N/A GLY 15.A N VAL 22.A O no hydrogen 3.235 N/A GLY 17.A N GLY 20.A O no hydrogen 2.880 N/A VAL 22.A N GLY 15.A O no hydrogen 2.808 N/A GLU 23.A N VAL 36.A O no hydrogen 2.878 N/A LYS 24.A N MET 12.A O no hydrogen 2.414 N/A MET 25.A N MET 34.A O no hydrogen 2.836 N/A ARG 26.A N GLU 9.A O no hydrogen 2.842 N/A ARG 26.A NE GLU 9.A OE2 no hydrogen 3.424 N/A ARG 26.A NH1 GLU 9.A OE2 no hydrogen 3.555 N/A HIS 27.A N GLN 32.A O no hydrogen 2.785 N/A HIS 27.A ND1 SER 30.A OG no hydrogen 2.645 N/A VAL 28.A N ASP 7.A O no hydrogen 3.334 N/A SER 30.A OG HIS 27.A ND1 no hydrogen 2.645 N/A SER 30.A OG HIS 27.A O no hydrogen 3.473 N/A GLY 31.A N HIS 27.A O no hydrogen 2.568 N/A GLN 32.A N SER 30.A OG no hydrogen 3.289 N/A MET 34.A N MET 25.A O no hydrogen 2.609 N/A ALA 35.A N MET 81.A O no hydrogen 3.123 N/A VAL 36.A N GLU 23.A O no hydrogen 2.939 N/A LYS 37.A N ILE 79.A O no hydrogen 2.842 N/A ARG 38.A N VAL 21.A O no hydrogen 2.576 N/A ILE 39.A N VAL 77.A O no hydrogen 2.968 N/A GLN 45.A N ASN 41.A O no hydrogen 2.812 N/A LYS 46.A N SER 42.A O no hydrogen 3.181 N/A ARG 47.A NE ASP 51.A OD2 no hydrogen 3.211 N/A LEU 49.A N GLN 45.A O no hydrogen 3.312 N/A MET 50.A N LYS 46.A O no hydrogen 3.040 N/A ASP 51.A N ARG 47.A O no hydrogen 2.747 N/A LEU 52.A N LEU 48.A O no hydrogen 3.064 N/A ASP 53.A N LEU 49.A O no hydrogen 3.086 N/A ILE 54.A N MET 50.A O no hydrogen 3.196 N/A SER 55.A N ASP 51.A O no hydrogen 3.070 N/A SER 55.A OG ASP 51.A O no hydrogen 3.204 N/A MET 56.A N LEU 52.A O no hydrogen 2.994 N/A ARG 57.A NE ASP 53.A O no hydrogen 3.333 N/A THR 58.A N SER 55.A O no hydrogen 3.373 N/A VAL 65.A N MET 147.A O no hydrogen 2.801 N/A THR 66.A N GLU 82.A OE2 no hydrogen 3.055 N/A THR 66.A OG1 GLU 82.A OE2 no hydrogen 3.058 N/A TYR 68.A N CYS 80.A O no hydrogen 2.841 N/A LEU 71.A N TRP 78.A O no hydrogen 2.817 N/A ARG 73.A N ASP 76.A O no hydrogen 3.186 N/A VAL 77.A N ILE 39.A O no hydrogen 2.792 N/A TRP 78.A N LEU 71.A O no hydrogen 2.718 N/A ILE 79.A N LYS 37.A O no hydrogen 2.884 N/A CYS 80.A N GLY 69.A O no hydrogen 2.760 N/A MET 81.A N ALA 35.A O no hydrogen 2.820 N/A GLU 82.A N THR 66.A O no hydrogen 2.829 N/A ASP 85.A N ILE 139.A O no hydrogen 2.960 N/A THR 86.A N ILE 139.A O no hydrogen 3.354 N/A SER 87.A OG ASP 89.A OD1 no hydrogen 2.561 N/A LEU 88.A N PRO 134.A O no hydrogen 3.062 N/A LEU 88.A N VAL 137.A O no hydrogen 2.832 N/A PHE 91.A N SER 87.A O no hydrogen 3.085 N/A TYR 92.A N LEU 88.A O no hydrogen 3.064 N/A TYR 92.A OH GLU 184.A OE2 no hydrogen 2.617 N/A LYS 93.A N ASP 89.A O no hydrogen 3.222 N/A GLN 94.A N LYS 90.A O no hydrogen 3.177 N/A GLN 94.A N PHE 91.A O no hydrogen 2.997 N/A VAL 95.A N PHE 91.A O no hydrogen 3.057 N/A ILE 96.A N TYR 92.A O no hydrogen 3.114 N/A ASP 97.A N LYS 93.A O no hydrogen 3.169 N/A LYS 98.A N GLN 94.A O no hydrogen 3.010 N/A LYS 98.A NZ ILE 266.A O no hydrogen 2.997 N/A GLY 99.A N ILE 96.A O no hydrogen 2.869 N/A GLN 100.A N VAL 95.A O no hydrogen 3.002 N/A LEU 107.A N PRO 103.A O no hydrogen 3.052 N/A GLY 108.A N GLU 104.A O no hydrogen 2.657 N/A LYS 109.A N ASP 105.A O no hydrogen 3.275 N/A LYS 109.A NZ HIS 252.A O no hydrogen 2.562 N/A LYS 109.A NZ LYS 255.A O no hydrogen 2.507 N/A ILE 110.A N ILE 106.A O no hydrogen 3.056 N/A ALA 111.A N LEU 107.A O no hydrogen 2.826 N/A VAL 112.A N GLY 108.A O no hydrogen 2.912 N/A SER 113.A N LYS 109.A O no hydrogen 3.202 N/A SER 113.A OG LYS 109.A O no hydrogen 2.539 N/A ILE 114.A N ILE 110.A O no hydrogen 3.082 N/A VAL 115.A N ALA 111.A O no hydrogen 3.052 N/A LYS 116.A N VAL 112.A O no hydrogen 2.919 N/A LYS 116.A NZ GLU 253.A OE2 no hydrogen 2.624 N/A ALA 117.A N SER 113.A O no hydrogen 2.929 N/A LEU 118.A N ILE 114.A O no hydrogen 2.759 N/A GLU 119.A N VAL 115.A O no hydrogen 2.880 N/A HIS 120.A N LYS 116.A O no hydrogen 3.012 N/A LEU 121.A N ALA 117.A O no hydrogen 3.070 N/A HIS 122.A N LEU 118.A O no hydrogen 2.959 N/A SER 123.A N GLU 119.A O no hydrogen 2.767 N/A SER 123.A OG GLU 119.A O no hydrogen 2.744 N/A SER 123.A OG GLU 119.A OE2 no hydrogen 2.778 N/A LYS 124.A N HIS 120.A O no hydrogen 2.701 N/A LEU 125.A N LEU 121.A O no hydrogen 3.125 N/A VAL 127.A N LEU 121.A O no hydrogen 2.844 N/A ARG 130.A N ASP 174.A OD2 no hydrogen 3.030 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.062 N/A LYS 133.A NZ ASP 131.A OD1 no hydrogen 3.504 N/A ASN 136.A N LYS 133.A O no hydrogen 2.841 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.665 N/A VAL 137.A N PRO 134.A O no hydrogen 3.224 N/A LEU 138.A N LYS 146.A O no hydrogen 2.832 N/A ILE 139.A N THR 86.A O no hydrogen 2.916 N/A ASN 140.A N GLN 144.A O no hydrogen 3.021 N/A ASN 140.A ND2 GLN 144.A OE1 no hydrogen 3.020 N/A GLY 143.A N ASN 140.A O no hydrogen 2.789 N/A GLN 144.A N ASN 140.A OD1 no hydrogen 2.755 N/A LYS 146.A N LEU 138.A O no hydrogen 2.937 N/A LYS 146.A NZ GLU 82.A OE1 no hydrogen 2.922 N/A LYS 146.A NZ GLU 82.A OE2 no hydrogen 3.041 N/A LYS 146.A NZ GLN 144.A OE1 no hydrogen 3.323 N/A MET 147.A N PHE 63.A O no hydrogen 2.913 N/A PHE 150.A N CYS 148.A O no hydrogen 2.834 N/A CYS 153.A N ALA 151.A O no hydrogen 2.781 N/A CYS 153.A SG ALA 151.A O no hydrogen 4.024 N/A LYS 154.A NZ SER 194.A OG no hydrogen 3.101 N/A TYR 156.A OH GLU 184.A OE1 no hydrogen 2.392 N/A TYR 156.A OH GLU 184.A OE2 no hydrogen 3.108 N/A GLU 160.A N GLU 160.A OE1 no hydrogen 2.970 N/A ARG 161.A N ALA 158.A O no hydrogen 2.937 N/A ILE 162.A N ALA 158.A O no hydrogen 3.209 N/A ASN 163.A N PRO 159.A O no hydrogen 2.849 N/A GLU 165.A N GLN 168.A OE1 no hydrogen 3.050 N/A GLN 168.A N GLU 165.A O no hydrogen 3.213 N/A GLN 168.A NE2 GLU 160.A O no hydrogen 2.815 N/A LYS 172.A NZ SER 234.A O no hydrogen 3.193 N/A LYS 172.A NZ ARG 237.A O no hydrogen 2.746 N/A SER 173.A N SER 170.A O no hydrogen 3.130 N/A SER 173.A OG SER 170.A O no hydrogen 2.866 N/A ILE 175.A N VAL 171.A O no hydrogen 2.969 N/A TRP 176.A N LYS 172.A O no hydrogen 3.073 N/A SER 177.A N SER 173.A O no hydrogen 3.176 N/A SER 177.A OG TYR 156.A O no hydrogen 2.709 N/A SER 177.A OG SER 173.A O no hydrogen 3.161 N/A LEU 178.A N ASP 174.A O no hydrogen 2.932 N/A GLY 179.A N ILE 175.A O no hydrogen 3.069 N/A ILE 180.A N TRP 176.A O no hydrogen 3.063 N/A THR 181.A N SER 177.A O no hydrogen 2.996 N/A THR 181.A OG1 SER 177.A O no hydrogen 2.921 N/A MET 182.A N LEU 178.A O no hydrogen 3.069 N/A ILE 183.A N GLY 179.A O no hydrogen 3.253 N/A GLU 184.A N ILE 180.A O no hydrogen 2.914 N/A LEU 185.A N THR 181.A O no hydrogen 3.069 N/A ALA 186.A N MET 182.A O no hydrogen 2.956 N/A ILE 187.A N ILE 183.A O no hydrogen 2.888 N/A LEU 188.A N GLU 184.A O no hydrogen 2.721 N/A ARG 189.A N GLU 184.A O no hydrogen 3.260 N/A SER 194.A OG TYR 192.A O no hydrogen 3.133 N/A THR 197.A N GLN 200.A OE1 no hydrogen 3.033 N/A GLN 200.A N THR 197.A OG1 no hydrogen 3.357 N/A GLN 201.A N THR 197.A O no hydrogen 2.965 N/A GLN 201.A NE2 GLY 196.A O no hydrogen 3.100 N/A GLN 201.A NE2 THR 197.A O no hydrogen 3.450 N/A LEU 202.A N PRO 198.A O no hydrogen 3.058 N/A LYS 203.A N PHE 199.A O no hydrogen 2.746 N/A GLN 204.A N GLN 200.A O no hydrogen 3.064 N/A GLN 204.A NE2 GLU 208.A OE1 no hydrogen 3.081 N/A VAL 206.A N LEU 202.A O no hydrogen 3.085 N/A GLU 207.A N LYS 203.A O no hydrogen 2.717 N/A GLU 208.A N GLN 204.A O no hydrogen 2.773 N/A SER 210.A OG LEU 230.A O no hydrogen 2.608 N/A LYS 217.A N PRO 214.A O no hydrogen 3.166 N/A LYS 217.A NZ ASP 216.A OD1 no hydrogen 3.341 N/A SER 219.A N GLU 104.A OE2 no hydrogen 2.631 N/A SER 219.A OG GLU 104.A OE1 no hydrogen 2.632 N/A SER 219.A OG GLU 104.A OE2 no hydrogen 3.218 N/A SER 219.A OG GLU 221.A OE1 no hydrogen 3.252 N/A GLU 221.A N GLU 221.A OE2 no hydrogen 2.889 N/A PHE 222.A N SER 219.A OG no hydrogen 3.137 N/A VAL 223.A N SER 219.A O no hydrogen 2.939 N/A ASP 224.A N ALA 220.A O no hydrogen 2.857 N/A PHE 225.A N GLU 221.A O no hydrogen 2.844 N/A THR 226.A N PHE 222.A O no hydrogen 3.078 N/A THR 226.A OG1 PHE 222.A O no hydrogen 3.115 N/A THR 226.A OG1 VAL 223.A O no hydrogen 3.083 N/A SER 227.A N VAL 223.A O no hydrogen 3.202 N/A SER 227.A OG ASP 224.A O no hydrogen 3.058 N/A GLN 228.A N ASP 224.A O no hydrogen 3.025 N/A GLN 228.A NE2 ASP 224.A OD1 no hydrogen 3.532 N/A CYS 229.A N PHE 225.A O no hydrogen 3.252 N/A CYS 229.A SG PHE 225.A O no hydrogen 3.513 N/A LEU 230.A N THR 226.A O no hydrogen 3.084 N/A LYS 232.A NZ VAL 205.A O no hydrogen 3.373 N/A LYS 232.A NZ VAL 206.A O no hydrogen 2.896 N/A LYS 232.A NZ GLU 208.A O no hydrogen 2.680 N/A ASN 233.A ND2 GLU 236.A OE2 no hydrogen 3.274 N/A LYS 235.A N ASN 233.A OD1 no hydrogen 3.218 N/A GLU 236.A N ASN 233.A O no hydrogen 3.040 N/A ARG 237.A N SER 234.A O no hydrogen 3.292 N/A ARG 237.A NE LYS 231.A O no hydrogen 2.632 N/A ARG 237.A NH1 GLU 160.A OE1 no hydrogen 3.420 N/A ARG 237.A NH1 GLU 160.A OE2 no hydrogen 2.780 N/A ARG 237.A NH1 LYS 172.A O no hydrogen 2.959 N/A ARG 237.A NH2 GLU 160.A OE1 no hydrogen 2.778 N/A ARG 237.A NH2 LYS 231.A O no hydrogen 3.158 N/A ARG 237.A NH2 LYS 232.A O no hydrogen 3.032 N/A THR 239.A N GLU 242.A OE1 no hydrogen 3.191 N/A GLU 242.A N THR 239.A OG1 no hydrogen 3.170 N/A LEU 243.A N THR 239.A O no hydrogen 3.012 N/A MET 244.A N TYR 240.A O no hydrogen 2.822 N/A GLN 245.A N GLU 242.A O no hydrogen 3.209 N/A HIS 246.A N LEU 243.A O no hydrogen 3.120 N/A HIS 246.A NE2 ASP 224.A OD2 no hydrogen 2.734 N/A PHE 248.A N HIS 246.A ND1 no hydrogen 3.204 N/A THR 250.A N HIS 246.A O no hydrogen 2.947 N/A THR 250.A OG1 HIS 246.A O no hydrogen 3.364 N/A LEU 251.A N PRO 247.A O no hydrogen 3.042 N/A HIS 252.A N PHE 248.A O no hydrogen 3.318 N/A HIS 252.A N PHE 249.A O no hydrogen 3.232 N/A GLU 253.A N PHE 249.A O no hydrogen 2.899 N/A VAL 259.A N THR 257.A O no hydrogen 3.083 N/A SER 261.A N ASP 258.A OD1 no hydrogen 3.214 N/A SER 261.A OG ASP 258.A OD1 no hydrogen 3.251 N/A SER 261.A OG ASP 258.A OD2 no hydrogen 2.664 N/A VAL 263.A N VAL 259.A O no hydrogen 2.936 N/A LYS 264.A N ALA 260.A O no hydrogen 2.988 N/A LEU 265.A N SER 261.A O no hydrogen 2.998 N/A ILE 266.A N PHE 262.A O no hydrogen 3.019 N/A LEU 267.A N VAL 263.A O no hydrogen 2.749 N/A GLY 268.A N LYS 264.A O no hydrogen 2.632 N/A