Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3fns_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A ND2 PHE 2.A O no hydrogen 3.003 N/A VAL 5.A N LEU 167.A O no hydrogen 2.918 N/A LEU 7.A N GLY 165.A O no hydrogen 2.618 N/A LYS 8.A N PHE 16.A O no hydrogen 2.885 N/A LEU 10.A N VAL 13.A O no hydrogen 3.177 N/A ASN 12.A N ASP 9.A OD1 no hydrogen 3.080 N/A LEU 14.A N ASP 302.A OD2 no hydrogen 2.876 N/A SER 15.A OG PHE 32.A O no hydrogen 3.285 N/A SER 15.A OG SER 214.A O no hydrogen 3.315 N/A GLY 17.A N PHE 30.A O no hydrogen 2.901 N/A ALA 19.A N PHE 28.A O no hydrogen 3.317 N/A LYS 20.A N THR 91.A O no hydrogen 2.690 N/A LEU 21.A N GLN 26.A O no hydrogen 2.815 N/A GLY 22.A N LEU 89.A O no hydrogen 2.573 N/A ASP 23.A N SER 62.A OG no hydrogen 3.115 N/A ASP 23.A N THR 64.A OG1 no hydrogen 3.157 N/A ASN 24.A N ASN 24.A OD1 no hydrogen 2.559 N/A GLY 25.A N GLY 22.A O no hydrogen 3.113 N/A GLN 26.A N LEU 21.A O no hydrogen 2.955 N/A GLN 26.A NE2 ASN 24.A OD1 no hydrogen 2.774 N/A GLN 26.A NE2 ASP 58.A O no hydrogen 3.391 N/A PHE 28.A N ALA 19.A O no hydrogen 3.133 N/A ASN 29.A N ASP 120.A OD2 no hydrogen 2.495 N/A ASN 29.A ND2 ASP 118.A O no hydrogen 2.949 N/A PHE 30.A N GLY 17.A O no hydrogen 2.754 N/A LEU 31.A N GLY 121.A O no hydrogen 2.978 N/A PHE 32.A N SER 15.A O no hydrogen 2.855 N/A HIS 33.A N PHE 123.A O no hydrogen 2.962 N/A THR 34.A N SER 214.A OG no hydrogen 3.381 N/A THR 34.A OG1 LEU 212.A O no hydrogen 3.175 N/A SER 36.A OG HIS 33.A ND1 no hydrogen 2.957 N/A SER 37.A OG TRP 127.A O no hydrogen 2.698 N/A ASN 38.A ND2 ILE 132.A O no hydrogen 3.201 N/A TRP 40.A N VAL 122.A O no hydrogen 2.848 N/A VAL 41.A N ILE 102.A O no hydrogen 3.074 N/A SER 43.A N MET 104.A O no hydrogen 2.863 N/A SER 43.A OG GLU 103.A OE2 no hydrogen 2.647 N/A ILE 44.A N TYR 57.A O no hydrogen 2.946 N/A LYS 45.A N SER 43.A OG no hydrogen 2.941 N/A CYS 46.A N SER 43.A O no hydrogen 2.981 N/A CYS 46.A SG THR 105.A O no hydrogen 3.595 N/A THR 47.A N THR 105.A O no hydrogen 3.288 N/A SER 50.A OG GLU 111B.A OE2 no hydrogen 3.524 N/A CYS 51.A N SER 48.A O no hydrogen 3.072 N/A LYS 54.A N CYS 51.A O no hydrogen 3.113 N/A LYS 54.A NZ TYR 114.A O no hydrogen 2.844 N/A LYS 54.A NZ SER 117.A O no hydrogen 2.891 N/A LYS 54.A NZ VAL 119.A O no hydrogen 2.865 N/A ASN 55.A N ASP 120.A OD1 no hydrogen 2.981 N/A ASN 55.A ND2 ASP 120.A OD1 no hydrogen 3.225 N/A ASN 55.A ND2 ASP 120.A OD2 no hydrogen 2.566 N/A TYR 57.A N PRO 42.A O no hydrogen 2.871 N/A TYR 57.A OH ASP 88.A OD2 no hydrogen 2.517 N/A ASP 58.A N GLN 26.A OE1 no hydrogen 2.780 N/A SER 60.A N ASP 58.A OD2 no hydrogen 3.362 N/A SER 60.A OG ASP 58.A OD2 no hydrogen 2.390 N/A LYS 61.A N ASP 58.A O no hydrogen 3.354 N/A SER 62.A N SER 59.A O no hydrogen 3.354 N/A SER 62.A OG ASP 88.A OD1 no hydrogen 3.335 N/A SER 62.A OG ASP 88.A OD2 no hydrogen 2.980 N/A THR 64.A OG1 SER 62.A OG no hydrogen 3.189 N/A THR 64.A OG1 ASP 88.A OD1 no hydrogen 2.733 N/A GLU 66.A N LYS 87.A O no hydrogen 3.008 N/A ASP 69.A N PHE 85.A O no hydrogen 2.768 N/A THR 70.A N ASP 68.A OD2 no hydrogen 2.734 N/A THR 70.A OG1 ASP 68.A OD2 no hydrogen 2.776 N/A VAL 72.A N GLY 83.A O no hydrogen 2.989 N/A LEU 74.A N ILE 81.A O no hydrogen 3.002 N/A SER 76.A N GLY 79.A O no hydrogen 2.946 N/A SER 76.A OG GLY 79.A O no hydrogen 3.516 N/A ALA 78.A N SER 76.A OG no hydrogen 3.083 N/A GLY 79.A N SER 76.A O no hydrogen 3.373 N/A THR 80.A N VAL 108.A O no hydrogen 2.832 N/A THR 80.A OG1 LEU 74.A O no hydrogen 3.158 N/A ILE 81.A N LEU 74.A O no hydrogen 2.965 N/A SER 82.A N GLU 106.A O no hydrogen 3.184 N/A GLY 83.A N VAL 72.A O no hydrogen 3.208 N/A ILE 84.A N GLU 103.A O no hydrogen 2.948 N/A PHE 85.A N THR 70.A O no hydrogen 2.936 N/A SER 86.A N PHE 101.A O no hydrogen 3.011 N/A SER 86.A OG GLU 103.A OE1 no hydrogen 2.549 N/A LYS 87.A N GLU 66.A O no hydrogen 3.244 N/A ASP 88.A N TYR 99.A O no hydrogen 3.074 N/A LEU 89.A N ASP 88.A OD1 no hydrogen 2.780 N/A VAL 90.A N VAL 97.A O no hydrogen 2.694 N/A THR 91.A N LYS 20.A O no hydrogen 2.765 N/A THR 91.A OG1 SER 96.A OG no hydrogen 2.772 N/A LYS 94.A N ASP 3.A OD2 no hydrogen 3.103 N/A LEU 95.A N ILE 92.A O no hydrogen 3.206 N/A SER 96.A OG THR 91.A OG1 no hydrogen 2.772 N/A VAL 97.A N VAL 90.A O no hydrogen 3.146 N/A TYR 99.A N ASP 88.A O no hydrogen 2.673 N/A TYR 99.A OH ASP 136.A O no hydrogen 3.045 N/A LYS 100.A NZ ASP 68.A OD1 no hydrogen 2.538 N/A PHE 101.A N SER 86.A O no hydrogen 2.916 N/A ILE 102.A N VAL 39.A O no hydrogen 2.948 N/A GLU 103.A N ILE 84.A O no hydrogen 2.781 N/A MET 104.A N VAL 41.A O no hydrogen 2.614 N/A THR 105.A N SER 82.A O no hydrogen 2.838 N/A GLU 106.A N SER 82.A O no hydrogen 3.121 N/A ILE 107.A N SER 48.A OG no hydrogen 3.007 N/A VAL 108.A N THR 80.A O no hydrogen 3.055 N/A TYR 114.A N PHE 110A.A O no hydrogen 3.409 N/A TYR 114.A OH ASP 120.A O no hydrogen 2.457 N/A SER 115.A OG PRO 112.A O no hydrogen 3.327 N/A SER 115.A OG GLU 111B.A OE1 no hydrogen 2.528 N/A GLU 116.A N PRO 112.A O no hydrogen 2.890 N/A SER 117.A N TYR 114.A O no hydrogen 3.091 N/A ASP 120.A N ASN 29.A O no hydrogen 2.735 N/A GLY 121.A N ASN 29.A O no hydrogen 3.432 N/A PHE 123.A N LEU 31.A O no hydrogen 2.822 N/A GLY 124.A N ASN 38.A O no hydrogen 2.950 N/A LEU 125.A N HIS 33.A O no hydrogen 2.665 N/A GLY 126.A N SER 36.A O no hydrogen 2.879 N/A LEU 130.A N TRP 127.A O no hydrogen 3.321 N/A SER 131.A N LYS 128.A O no hydrogen 2.846 N/A SER 131.A OG LYS 128.A O no hydrogen 2.967 N/A SER 131.A OG ILE 135.A O no hydrogen 3.324 N/A ILE 132.A N ASN 38.A OD1 no hydrogen 2.993 N/A SER 134.A N SER 131.A O no hydrogen 3.317 N/A ILE 135.A N SER 131.A OG no hydrogen 2.909 N/A TYR 138.A OH VAL 90.A O no hydrogen 2.936 N/A GLU 141.A N PRO 137.A O no hydrogen 3.037 N/A LEU 142.A N TYR 138.A O no hydrogen 3.142 N/A LYS 143.A N ILE 139.A O no hydrogen 3.229 N/A LYS 143.A NZ ASP 315.A OD1 no hydrogen 3.164 N/A THR 144.A N VAL 140.A O no hydrogen 2.846 N/A THR 144.A OG1 VAL 140.A O no hydrogen 3.003 N/A GLN 145.A N GLU 141.A O no hydrogen 3.133 N/A ASN 146.A N LYS 143.A O no hydrogen 2.956 N/A LYS 147.A N LEU 142.A O no hydrogen 2.883 N/A GLN 150.A NE2 GLY 170.A O no hydrogen 3.110 N/A ALA 151.A N ASP 315.A OD2 no hydrogen 2.780 N/A VAL 152.A N GLN 150.A O no hydrogen 2.886 N/A TYR 153.A N TYR 312.A O no hydrogen 2.950 N/A TYR 153.A OH LEU 125.A O no hydrogen 2.901 N/A SER 154.A N THR 168.A O no hydrogen 2.932 N/A ILE 155.A N THR 310.A O no hydrogen 2.909 N/A TYR 156.A N TYR 166.A O no hydrogen 2.911 N/A TYR 156.A OH LYS 325.A O no hydrogen 2.603 N/A ASN 161.A ND2 ASN 161.A O no hydrogen 3.109 N/A LYS 164.A NZ GLU 6.A OE1 no hydrogen 3.180 N/A LYS 164.A NZ GLU 6.A OE2 no hydrogen 3.117 N/A TYR 166.A N TYR 156.A O no hydrogen 2.929 N/A LEU 167.A N VAL 5.A O no hydrogen 2.992 N/A THR 168.A N SER 154.A O no hydrogen 3.021 N/A THR 168.A OG1 ASN 4.A OD1 no hydrogen 2.775 N/A ILE 169.A N ASP 3.A O no hydrogen 2.847 N/A GLY 170.A N VAL 152.A O no hydrogen 2.905 N/A PHE 176.A N GLU 173.A O no hydrogen 3.377 N/A PHE 177.A N GLU 174.A O no hydrogen 3.494 N/A ASP 178.A N LEU 323.A O no hydrogen 3.172 N/A ASN 182.A N PHE 321.A O no hydrogen 2.824 N/A GLU 184.A N VAL 319.A O no hydrogen 2.741 N/A LEU 186.A N HIS 317.A O no hydrogen 2.967 N/A ASN 187.A N GLN 193.A O no hydrogen 3.133 N/A ASN 187.A ND2 ASP 195.A OD1 no hydrogen 3.062 N/A ASN 187.A ND2 ASN 209.A OD1 no hydrogen 2.893 N/A TRP 192.A NE1 LEU 125.A O no hydrogen 2.745 N/A VAL 194.A N VAL 210.A O no hydrogen 3.024 N/A LEU 196.A N ALA 208.A O no hydrogen 2.998 N/A ASP 197.A N ARG 259.A O no hydrogen 3.069 N/A VAL 198.A N SER 205.A O no hydrogen 3.107 N/A HIS 199.A N GLU 257.A O no hydrogen 2.877 N/A HIS 199.A NE2 ASP 197.A OD2 no hydrogen 3.033 N/A PHE 200.A N VAL 203.A O no hydrogen 2.981 N/A VAL 203.A N PHE 200.A O no hydrogen 3.415 N/A SER 205.A N VAL 198.A O no hydrogen 2.715 N/A ALA 208.A N LEU 196.A O no hydrogen 2.832 N/A ASN 209.A N ASN 296.A O no hydrogen 2.798 N/A ASN 209.A ND2 GLN 193.A OE1 no hydrogen 2.782 N/A ASN 209.A ND2 THR 297.A OG1 no hydrogen 3.308 N/A VAL 210.A N VAL 194.A O no hydrogen 2.995 N/A ILE 211.A N PHE 298.A O no hydrogen 2.826 N/A LEU 212.A N TRP 192.A O no hydrogen 3.018 N/A ASP 213.A N LEU 300.A O no hydrogen 2.722 N/A SER 214.A N THR 34.A OG1 no hydrogen 3.172 N/A SER 214.A OG PHE 32.A O no hydrogen 2.890 N/A ALA 215.A N ASP 213.A OD1 no hydrogen 3.036 N/A ILE 219.A N ASN 287.A O no hydrogen 3.282 N/A THR 220.A N VAL 299.A O no hydrogen 3.129 N/A VAL 221.A N VAL 289.A O no hydrogen 3.326 N/A THR 223.A N ASP 292.A OD1 no hydrogen 3.347 N/A THR 223.A OG1 ASP 292.A OD2 no hydrogen 2.950 N/A PHE 226.A N PRO 222.A O no hydrogen 3.012 N/A ASN 227.A N THR 223.A O no hydrogen 2.764 N/A GLN 228.A N GLU 224.A O no hydrogen 2.914 N/A PHE 229.A N PHE 225.A O no hydrogen 3.089 N/A VAL 230.A N PHE 226.A O no hydrogen 2.870 N/A GLU 231.A N ASN 227.A O no hydrogen 3.060 N/A SER 232.A N GLN 228.A O no hydrogen 3.017 N/A SER 232.A OG GLN 228.A O no hydrogen 3.562 N/A ALA 233.A N PHE 229.A O no hydrogen 2.660 N/A SER 234.A N VAL 230.A O no hydrogen 2.897 N/A SER 234.A OG VAL 230.A O no hydrogen 2.550 N/A VAL 235.A N GLU 231.A O no hydrogen 3.283 N/A PHE 236.A N SER 232.A O no hydrogen 3.472 N/A VAL 238.A N ALA 233.A O no hydrogen 3.186 N/A LEU 241.A N VAL 245.A O no hydrogen 2.896 N/A THR 246.A N CYS 284.A O no hydrogen 2.961 N/A THR 246.A OG1 PRO 239.A O no hydrogen 3.423 N/A CYS 248.A N ALA 282.A O no hydrogen 3.232 N/A CYS 248.A SG SER 281C.A O no hydrogen 3.729 N/A ASN 250.A N THR 247.A O no hydrogen 3.261 N/A ASN 250.A ND2 PRO 239.A O no hydrogen 3.492 N/A ASN 250.A ND2 THR 246.A OG1 no hydrogen 2.615 N/A LYS 252.A N ASN 250.A OD1 no hydrogen 3.268 N/A LYS 252.A NZ PHE 236.A O no hydrogen 3.186 N/A LEU 256.A N LEU 267.A O no hydrogen 2.916 N/A GLU 257.A N HIS 199.A O no hydrogen 2.793 N/A TYR 258.A N TYR 265.A O no hydrogen 2.677 N/A ARG 259.A N ASP 197.A O no hydrogen 2.862 N/A ARG 259.A NH1 GLU 257.A OE2 no hydrogen 2.702 N/A SER 260.A N LYS 263.A O no hydrogen 2.802 N/A SER 260.A OG GLU 184.A OE1 no hydrogen 3.563 N/A SER 260.A OG GLU 184.A OE2 no hydrogen 2.924 N/A SER 260.A OG LYS 263.A O no hydrogen 3.025 N/A ASN 262.A N SER 260.A OG no hydrogen 3.079 N/A ASN 262.A ND2 PRO 261.A O no hydrogen 2.993 N/A LYS 263.A N SER 260.A OG no hydrogen 2.813 N/A TYR 265.A N TYR 258.A O no hydrogen 2.790 N/A TYR 265.A OH GLU 184.A OE2 no hydrogen 2.687 N/A THR 266.A N TYR 308.A OH no hydrogen 3.050 N/A LEU 267.A N LEU 256.A O no hydrogen 2.872 N/A GLU 268.A N GLN 271.A OE1 no hydrogen 2.756 N/A GLN 271.A N GLU 268.A O no hydrogen 2.587 N/A TYR 272.A N GLU 268.A O no hydrogen 3.278 N/A TYR 272.A N PRO 269.A O no hydrogen 2.935 N/A TYR 272.A OH PRO 254.A O no hydrogen 2.724 N/A GLU 274.A N MET 285.A O no hydrogen 2.892 N/A LEU 276.A N LEU 283.A O no hydrogen 3.005 N/A LEU 283.A N SER 281C.A OG no hydrogen 2.995 N/A CYS 284.A N THR 246.A O no hydrogen 2.908 N/A CYS 284.A SG LEU 283.A O no hydrogen 3.700 N/A MET 285.A N GLU 274.A O no hydrogen 2.704 N/A LEU 286.A N TYR 244.A O no hydrogen 2.929 N/A ASN 287.A N TYR 272.A O no hydrogen 2.666 N/A ASN 287.A ND2 SER 217.A O no hydrogen 2.636 N/A VAL 289.A N ILE 219.A O no hydrogen 2.844 N/A ILE 291.A N VAL 221.A O no hydrogen 2.837 N/A THR 297.A N GLU 294.A O no hydrogen 3.173 N/A THR 297.A OG1 GLU 294.A O no hydrogen 3.324 N/A THR 297.A OG1 LYS 295.A O no hydrogen 3.083 N/A PHE 298.A N ASN 209.A O no hydrogen 2.880 N/A VAL 299.A N THR 220.A O no hydrogen 3.406 N/A VAL 299.A N THR 220.A OG1 no hydrogen 3.146 N/A LEU 300.A N ILE 211.A O no hydrogen 2.739 N/A ASP 302.A N THR 216.A O no hydrogen 2.867 N/A MET 305.A N GLY 301.A O no hydrogen 3.280 N/A ARG 306.A N ASP 302.A O no hydrogen 2.558 N/A ARG 306.A NH1 ASN 12.A O no hydrogen 3.196 N/A LYS 307.A N PHE 304.A O no hydrogen 3.072 N/A LYS 307.A NZ THR 266.A O no hydrogen 2.933 N/A LYS 307.A NZ TYR 308.A OH no hydrogen 3.377 N/A TYR 308.A N PHE 304.A O no hydrogen 2.869 N/A PHE 309.A N ALA 322.A O no hydrogen 2.698 N/A THR 310.A N ILE 155.A O no hydrogen 3.263 N/A THR 310.A OG1 TYR 312.A OH no hydrogen 2.812 N/A VAL 311.A N GLY 320.A O no hydrogen 2.838 N/A TYR 312.A N TYR 153.A O no hydrogen 2.676 N/A TYR 312.A OH THR 310.A OG1 no hydrogen 2.812 N/A ASP 313.A N THR 318.A O no hydrogen 2.968 N/A TYR 314.A N ALA 151.A O no hydrogen 2.896 N/A TYR 314.A OH GLY 126.A O no hydrogen 3.151 N/A ASN 316.A N ASP 313.A OD1 no hydrogen 2.967 N/A ASN 316.A ND2 ASP 313.A OD1 no hydrogen 3.089 N/A ASN 316.A ND2 ASP 313.A OD2 no hydrogen 2.712 N/A THR 318.A N ASP 313.A O no hydrogen 3.182 N/A VAL 319.A N GLU 184.A O no hydrogen 3.009 N/A GLY 320.A N VAL 311.A O no hydrogen 2.788 N/A PHE 321.A N ASN 182.A O no hydrogen 2.779 N/A ALA 322.A N PHE 309.A O no hydrogen 3.175 N/A ALA 324.A N LYS 307.A O no hydrogen 2.924 N/A LYS 325.A N PHE 176.A O no hydrogen 2.926 N/A PHE 110A.A N ALA 78.A O no hydrogen 2.647 N/A SER 281C.A OG LEU 283.A O no hydrogen 2.471 N/A