Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3fo8_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 ASP 1.A OD1 no hydrogen 3.080 N/A LYS 4.A N LEU 258.A O no hydrogen 2.908 N/A ASN 5.A N ILE 107.A O no hydrogen 2.835 N/A ASN 5.A ND2 ALA 138.A O no hydrogen 2.811 N/A ASN 5.A ND2 LEU 139.A O no hydrogen 2.916 N/A SER 6.A OG ASP 146.A OD1 no hydrogen 2.688 N/A SER 7.A N SER 255.A O no hydrogen 2.979 N/A SER 7.A OG SER 105.A O no hydrogen 2.705 N/A ILE 9.A N SER 7.A OG no hydrogen 3.090 N/A GLY 11.A N ILE 102.A O no hydrogen 2.796 N/A ASN 12.A N ILE 9.A O no hydrogen 3.230 N/A GLU 14.A N LYS 100.A O no hydrogen 2.872 N/A TYR 15.A OH LYS 130.A O no hydrogen 2.784 N/A THR 16.A N THR 97.A O no hydrogen 2.839 N/A SER 18.A OG THR 97.A OG1 no hydrogen 2.569 N/A THR 19.A N VAL 95.A O no hydrogen 3.261 N/A SER 22.A N LEU 92.A O no hydrogen 3.188 N/A ASN 23.A N ASP 51.A O no hydrogen 2.944 N/A TYR 24.A N GLY 52.A O no hydrogen 2.920 N/A ALA 25.A N ASP 28.A OD2 no hydrogen 2.946 N/A GLY 27.A N ILE 45.A O no hydrogen 2.893 N/A ASP 28.A N ALA 25.A O no hydrogen 3.091 N/A LYS 29.A NZ GLU 42.A OE2 no hydrogen 3.020 N/A ILE 30.A N GLY 43.A O no hydrogen 2.913 N/A THR 31.A N GLU 84.A O no hydrogen 2.892 N/A VAL 32.A N GLU 40.A O no hydrogen 2.840 N/A LYS 33.A N THR 82.A O no hydrogen 2.935 N/A LYS 33.A NZ GLU 84.A OE1 no hydrogen 3.209 N/A TYR 34.A N ASP 37.A O no hydrogen 2.848 N/A TYR 34.A OH GLU 73.A OE2 no hydrogen 2.729 N/A VAL 35.A N ASN 80.A O no hydrogen 2.827 N/A ASP 37.A N TYR 34.A O no hydrogen 2.984 N/A ILE 39.A N VAL 32.A O no hydrogen 2.902 N/A GLU 40.A N VAL 32.A O no hydrogen 3.198 N/A THR 41.A OG1 GLU 42.A OE1 no hydrogen 2.852 N/A GLU 42.A N GLU 40.A OE2 no hydrogen 2.930 N/A GLY 43.A N ILE 30.A O no hydrogen 3.168 N/A LYS 44.A N ASN 58.A O no hydrogen 2.823 N/A ILE 45.A N ASP 28.A O no hydrogen 2.960 N/A THR 46.A N LYS 56.A O no hydrogen 2.848 N/A GLU 47.A N LYS 56.A O no hydrogen 3.181 N/A ASP 49.A N LYS 53.A O no hydrogen 3.039 N/A ASP 51.A N ASP 49.A OD2 no hydrogen 2.759 N/A GLY 52.A N ASP 49.A O no hydrogen 2.985 N/A LYS 53.A N ASP 49.A OD2 no hydrogen 2.981 N/A ILE 54.A N PRO 20.A O no hydrogen 3.112 N/A LYS 55.A N GLU 47.A O no hydrogen 2.822 N/A LYS 56.A N GLU 47.A O no hydrogen 3.213 N/A LYS 56.A NZ GLU 47.A OE1 no hydrogen 3.207 N/A ILE 57.A N TYR 15.A OH no hydrogen 3.374 N/A ASN 58.A N LYS 44.A O no hydrogen 2.808 N/A THR 61.A N PRO 170.A O no hydrogen 2.901 N/A THR 61.A OG1 GLY 11.A O no hydrogen 2.725 N/A THR 61.A OG1 PRO 170.A O no hydrogen 3.451 N/A ALA 62.A N GLY 171.A O no hydrogen 2.961 N/A ILE 65.A N THR 61.A O no hydrogen 2.837 N/A ALA 66.A N ALA 62.A O no hydrogen 3.056 N/A LYS 67.A N LYS 63.A O no hydrogen 3.031 N/A LYS 67.A NZ GLU 70.A OE2.A no hydrogen 3.091 N/A ALA 68.A N ILE 64.A O no hydrogen 2.865 N/A LYS 69.A N ILE 65.A O no hydrogen 3.007 N/A GLU 70.A N.A ALA 66.A O no hydrogen 3.275 N/A GLU 70.A N.B ALA 66.A O no hydrogen 3.278 N/A GLU 70.A N.B LYS 67.A O no hydrogen 2.965 N/A VAL 71.A N LYS 67.A O no hydrogen 3.035 N/A GLU 73.A N ALA 68.A O no hydrogen 2.847 N/A THR 76.A OG1 LEU 77.A O no hydrogen 3.102 N/A LEU 77.A N GLU 73.A O no hydrogen 2.685 N/A TRP 81.A N GLY 78.A O no hydrogen 2.981 N/A TRP 81.A NE1 GLU 73.A OE1 no hydrogen 2.919 N/A THR 82.A N LYS 33.A O no hydrogen 3.049 N/A GLU 84.A N THR 31.A O no hydrogen 2.983 N/A SER 86.A N LYS 29.A O no hydrogen 2.779 N/A SER 86.A OG SER 88.A OG no hydrogen 2.835 N/A SER 88.A N SER 86.A OG no hydrogen 3.207 N/A SER 88.A OG SER 86.A OG no hydrogen 2.835 N/A SER 89.A N SER 86.A O no hydrogen 3.131 N/A SER 89.A OG ASP 28.A OD2 no hydrogen 2.787 N/A GLY 91.A N SER 89.A OG no hydrogen 2.855 N/A LEU 92.A N SER 22.A O no hydrogen 3.065 N/A ALA 94.A N TYR 24.A OH no hydrogen 3.026 N/A VAL 95.A N THR 19.A O no hydrogen 2.832 N/A THR 97.A N THR 16.A O no hydrogen 2.931 N/A THR 97.A OG1 SER 18.A OG no hydrogen 2.569 N/A GLY 99.A N GLU 14.A O no hydrogen 2.865 N/A LYS 100.A N GLU 14.A OE1 no hydrogen 3.010 N/A ILE 101.A N PRO 75.A O no hydrogen 2.826 N/A ILE 102.A N ASN 12.A O no hydrogen 2.854 N/A SER 105.A OG ASN 5.A O no hydrogen 2.663 N/A SER 105.A OG ILE 107.A O no hydrogen 3.277 N/A GLY 106.A N ASP 104.A OD1 no hydrogen 2.800 N/A ILE 107.A N SER 105.A OG no hydrogen 3.341 N/A LEU 109.A N ASN 5.A OD1 no hydrogen 2.877 N/A ASN 114.A N GLU 111.A O no hydrogen 2.724 N/A ALA 115.A N ILE 112.A O no hydrogen 3.491 N/A ALA 118.A N ASN 114.A O no hydrogen 3.489 N/A MET 119.A N ALA 115.A O no hydrogen 2.842 N/A THR 120.A N GLU 116.A O no hydrogen 3.030 N/A THR 120.A OG1 GLU 116.A O no hydrogen 2.919 N/A ALA 121.A N ALA 118.A O no hydrogen 3.315 N/A GLN 125.A N ALA 121.A O no hydrogen 2.977 N/A GLN 125.A NE2 MET 119.A O no hydrogen 2.964 N/A GLN 125.A NE2 GLN 242.A O no hydrogen 3.442 N/A ALA 126.A N VAL 122.A O no hydrogen 2.948 N/A ASN 127.A N ASP 123.A O no hydrogen 3.212 N/A LEU 128.A N PHE 124.A O no hydrogen 3.042 N/A LYS 129.A N GLN 125.A O no hydrogen 3.082 N/A LYS 130.A N ALA 126.A O no hydrogen 2.960 N/A LYS 130.A NZ TYR 15.A O no hydrogen 2.839 N/A TYR 131.A N ASN 127.A O no hydrogen 3.023 N/A TYR 131.A OH ILE 13.A O no hydrogen 3.029 N/A GLY 132.A N LYS 129.A O no hydrogen 3.279 N/A ILE 133.A N LEU 128.A O no hydrogen 3.183 N/A VAL 136.A N PRO 134.A O no hydrogen 3.156 N/A VAL 137.A N PHE 238.A O no hydrogen 2.899 N/A ALA 138.A N SER 6.A O no hydrogen 3.093 N/A LEU 139.A N TYR 236.A O no hydrogen 2.848 N/A GLY 142.A N LYS 4.A O no hydrogen 3.056 N/A GLU 143.A N GLU 143.A OE1 no hydrogen 2.567 N/A GLY 145.A N GLY 142.A O no hydrogen 3.117 N/A ASP 146.A N GLU 143.A O no hydrogen 3.022 N/A LYS 147.A N LEU 144.A O no hydrogen 3.098 N/A ILE 148.A N GLY 145.A O no hydrogen 3.144 N/A GLU 149.A N ARG 198.A O no hydrogen 2.912 N/A ILE 150.A N LEU 252.A O no hydrogen 3.013 N/A GLU 151.A N ILE 196.A O no hydrogen 2.837 N/A ILE 152.A N GLY 250.A O no hydrogen 2.841 N/A VAL 153.A N ALA 194.A O no hydrogen 2.907 N/A SER 154.A N SER 249.A OG no hydrogen 2.954 N/A SER 154.A OG SER 249.A OG no hydrogen 3.205 N/A ASP 157.A N SER 154.A OG no hydrogen 3.164 N/A TYR 158.A N SER 154.A O no hydrogen 2.802 N/A TYR 158.A OH PHE 183.A O no hydrogen 3.349 N/A ALA 159.A N LYS 155.A O no hydrogen 3.374 N/A LYS 160.A N ASP 157.A O no hydrogen 3.094 N/A LYS 160.A NZ ASP 157.A OD1 no hydrogen 2.852 N/A GLY 161.A N TYR 158.A O no hydrogen 3.002 N/A SER 163.A N LYS 160.A O no hydrogen 3.141 N/A ALA 164.A N GLY 161.A O no hydrogen 3.135 N/A LEU 166.A N ARG 175.A O no hydrogen 2.861 N/A ILE 168.A N GLY 173.A O no hydrogen 3.004 N/A TYR 169.A N ILE 251.A O no hydrogen 2.809 N/A GLY 172.A N ILE 168.A O no hydrogen 2.880 N/A ARG 175.A N LEU 166.A O no hydrogen 2.890 N/A ARG 175.A NH1 GLU 149.A OE1 no hydrogen 3.147 N/A ARG 175.A NH1 GLU 149.A OE2 no hydrogen 3.099 N/A ARG 175.A NH2 GLU 149.A OE1 no hydrogen 2.890 N/A ARG 175.A NH2 GLU 151.A OE1 no hydrogen 3.348 N/A SER 177.A N ALA 164.A O no hydrogen 2.861 N/A THR 178.A N GLU 151.A OE2 no hydrogen 2.866 N/A THR 178.A OG1 GLU 151.A OE1 no hydrogen 3.251 N/A THR 178.A OG1 GLU 151.A OE2 no hydrogen 2.994 N/A ALA 179.A N SER 177.A OG no hydrogen 3.191 N/A VAL 182.A N THR 178.A O no hydrogen 2.916 N/A PHE 183.A N ALA 179.A O no hydrogen 2.961 N/A GLN 188.A NE2 GLY 186.A O no hydrogen 2.953 N/A SER 191.A N THR 189.A OG1 no hydrogen 3.121 N/A GLN 192.A N THR 189.A O no hydrogen 3.031 N/A TYR 193.A N LEU 209.A O no hydrogen 2.916 N/A ALA 194.A N VAL 153.A O no hydrogen 2.865 N/A ILE 195.A N VAL 207.A O no hydrogen 2.789 N/A ILE 196.A N GLU 151.A O no hydrogen 2.816 N/A VAL 197.A N GLN 205.A O no hydrogen 2.802 N/A ARG 198.A N GLU 149.A O no hydrogen 2.895 N/A ARG 198.A NH1 GLU 151.A OE1 no hydrogen 2.936 N/A ARG 198.A NH2 THR 178.A OG1 no hydrogen 2.868 N/A ARG 199.A N ALA 202.A O no hydrogen 2.894 N/A ALA 202.A N ARG 199.A O no hydrogen 3.128 N/A VAL 204.A N VAL 197.A O no hydrogen 2.831 N/A GLN 205.A N VAL 197.A O no hydrogen 3.443 N/A GLN 205.A NE2 GLY 233.A O no hydrogen 3.078 N/A VAL 207.A N ILE 195.A O no hydrogen 2.931 N/A LEU 209.A N TYR 193.A O no hydrogen 3.060 N/A SER 210.A N ILE 223.A O no hydrogen 2.762 N/A SER 210.A OG SER 191.A O no hydrogen 3.505 N/A SER 210.A OG LYS 212.A O no hydrogen 3.548 N/A THR 211.A N SER 191.A O no hydrogen 2.861 N/A THR 211.A OG1 SER 191.A O no hydrogen 3.343 N/A LYS 212.A N SER 210.A OG no hydrogen 2.946 N/A GLY 215.A N LYS 212.A O no hydrogen 3.300 N/A LYS 216.A NZ GLY 214.A O no hydrogen 2.948 N/A ASP 217.A N SER 221.A O no hydrogen 2.928 N/A TYR 219.A N ASP 217.A OD2 no hydrogen 2.797 N/A ASP 220.A N ASP 217.A O no hydrogen 2.915 N/A SER 221.A N ASP 217.A OD2 no hydrogen 2.913 N/A ASN 222.A ND2 ASP 227.A OD1 no hydrogen 2.830 N/A ILE 223.A N GLY 215.A O no hydrogen 3.179 N/A TYR 224.A N ASN 222.A OD1 no hydrogen 2.937 N/A ILE 225.A N SER 210.A O no hydrogen 2.872 N/A PHE 228.A N TYR 224.A O no hydrogen 2.949 N/A PHE 229.A N ILE 225.A O no hydrogen 3.136 N/A ALA 230.A N ASP 226.A O no hydrogen 2.942 N/A LYS 231.A N ASP 227.A O no hydrogen 2.991 N/A GLY 232.A N PHE 229.A O no hydrogen 3.054 N/A GLY 233.A N PHE 228.A O no hydrogen 2.928 N/A SER 234.A OG GLN 205.A OE1 no hydrogen 2.768 N/A SER 234.A OG ILE 237.A O no hydrogen 3.415 N/A TYR 236.A N SER 234.A OG no hydrogen 2.930 N/A ILE 237.A N SER 234.A OG no hydrogen 3.006 N/A PHE 238.A N VAL 137.A O no hydrogen 2.819 N/A THR 240.A N GLY 135.A O no hydrogen 3.101 N/A THR 240.A OG1 ASP 226.A OD1 no hydrogen 2.797 N/A ALA 241.A N ASP 226.A OD2 no hydrogen 2.810 N/A GLN 242.A N THR 240.A OG1 no hydrogen 3.077 N/A ASN 243.A ND2 GLN 125.A OE1 no hydrogen 2.502 N/A TRP 244.A N ALA 241.A O no hydrogen 3.098 N/A GLY 247.A N TYR 193.A OH no hydrogen 2.806 N/A PHE 248.A N PRO 245.A O no hydrogen 2.988 N/A SER 249.A OG ASP 157.A OD2 no hydrogen 2.621 N/A GLY 250.A N ILE 152.A O no hydrogen 2.828 N/A ILE 251.A N PRO 167.A O no hydrogen 2.883 N/A LEU 252.A N ILE 150.A O no hydrogen 2.697 N/A THR 253.A N TYR 169.A O no hydrogen 2.871 N/A THR 253.A OG1 TYR 169.A O no hydrogen 3.324 N/A SER 255.A N SER 7.A O no hydrogen 2.945 N/A GLY 257.A N ASP 146.A OD1 no hydrogen 2.993 N/A LEU 258.A N LYS 4.A O no hydrogen 3.031 N/A SER 259.A OG GLU 143.A OE1 no hydrogen 2.711 N/A GLU 263.A N SER 260.A O no hydrogen 2.821 N/A VAL 264.A N ASN 261.A O no hydrogen 3.358 N/A THR 265.A N ASP 268.A OD2 no hydrogen 3.036 N/A ASP 268.A N THR 265.A O no hydrogen 2.976 N/A ASP 268.A N THR 265.A OG1 no hydrogen 3.036 N/A LEU 269.A N THR 265.A O no hydrogen 3.356 N/A MET 270.A N ALA 266.A O no hydrogen 2.949 N/A GLU 271.A N GLY 267.A O no hydrogen 2.963 N/A ALA 272.A N ASP 268.A O no hydrogen 3.090 N/A ALA 272.A N LEU 269.A O no hydrogen 2.986 N/A TRP 273.A N MET 270.A O no hydrogen 3.057 N/A