Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3h4x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N THR 6.A OG1 no hydrogen 2.922 N/A THR 3.A OG1 THR 6.A OG1 no hydrogen 3.366 N/A TYR 4.A N PRO 156.A O no hydrogen 3.089 N/A GLY 5.A N THR 3.A OG1 no hydrogen 2.953 N/A THR 6.A N THR 3.A O no hydrogen 3.051 N/A THR 6.A OG1 THR 3.A OG1 no hydrogen 3.366 N/A SER 7.A OG THR 3.A O no hydrogen 3.406 N/A THR 8.A N VAL 311.A O no hydrogen 2.755 N/A THR 8.A OG1 ALA 293.A O no hydrogen 2.729 N/A SER 9.A N SER 294.A O no hydrogen 2.893 N/A GLY 11.A N ALA 296.A O no hydrogen 2.865 N/A VAL 12.A N LEU 34.A O no hydrogen 2.934 N/A HIS 13.A N ALA 298.A O no hydrogen 2.886 N/A ASN 14.A N GLU 36.A OE1.B no hydrogen 2.964 N/A ASN 14.A ND2 HIS 52.A ND1 no hydrogen 2.656 N/A ALA 15.A N GLU 36.A O no hydrogen 2.948 N/A TYR 16.A OH ASP 38.A OD2 no hydrogen 2.567 N/A GLU 17.A N ASN 14.A O no hydrogen 3.264 N/A LYS 18.A NZ ASP 77.A OD1 no hydrogen 2.856 N/A LYS 18.A NZ ASP 77.A OD2 no hydrogen 3.525 N/A LYS 20.A N GLU 17.A O no hydrogen 2.949 N/A LYS 20.A NZ HIS 13.A O no hydrogen 3.257 N/A LYS 20.A NZ ASN 14.A O no hydrogen 3.101 N/A LYS 20.A NZ GLU 17.A OE1 no hydrogen 2.732 N/A TYR 21.A N GLU 17.A O no hydrogen 3.061 N/A TYR 23.A N ASP 26.A OD2 no hydrogen 3.060 N/A PHE 24.A N ASN 61.A O no hydrogen 2.888 N/A ASP 26.A N TYR 23.A O no hydrogen 2.807 N/A LEU 28.A N PHE 24.A O no hydrogen 2.961 N/A ASP 29.A N ALA 25.A O no hydrogen 2.855 N/A SER 30.A N ALA 27.A O no hydrogen 3.167 N/A SER 30.A OG ALA 27.A O no hydrogen 2.670 N/A ALA 32.A N SER 30.A OG no hydrogen 3.081 N/A ALA 33.A N VAL 10.A O no hydrogen 2.773 N/A LEU 35.A N LEU 101.A O no hydrogen 2.915 N/A GLU 36.A N VAL 12.A O no hydrogen 3.166 N/A LEU 37.A N LYS 103.A O no hydrogen 2.762 N/A LEU 39.A N GLU 105.A O no hydrogen 2.969 N/A TRP 40.A N ARG 49.A O no hydrogen 2.937 N/A TRP 40.A NE1 SER 51.A O no hydrogen 2.761 N/A SER 41.A N ASP 108.A OD1 no hydrogen 2.768 N/A SER 41.A OG GLY 109.A O no hydrogen 2.909 N/A ASN 42.A N ASP 108.A OD2 no hydrogen 2.783 N/A ASN 42.A ND2 ASP 108.A O no hydrogen 2.931 N/A ASN 42.A ND2 PHE 110.A O no hydrogen 3.026 N/A SER 47.A OG ARG 46.A O no hydrogen 2.467 N/A ARG 49.A N TRP 40.A O no hydrogen 3.062 N/A ARG 49.A NH1 GLY 57.A O no hydrogen 2.925 N/A ARG 49.A NH2 LEU 44.A O no hydrogen 2.733 N/A VAL 50.A N ASN 58.A OD1 no hydrogen 2.863 N/A SER 51.A N ASP 38.A O no hydrogen 3.315 N/A SER 51.A OG SER 53.A O no hydrogen 2.770 N/A ASN 58.A ND2 ASP 77.A O no hydrogen 3.656 N/A ASN 59.A N VAL 50.A O no hydrogen 2.944 N/A SER 60.A N ASP 77.A OD1 no hydrogen 2.982 N/A SER 60.A OG GLN 78.A O no hydrogen 2.852 N/A ASN 61.A N TYR 16.A O no hydrogen 2.811 N/A ASN 61.A ND2 ALA 15.A O no hydrogen 2.988 N/A ASN 61.A ND2 TYR 21.A O no hydrogen 2.924 N/A CYS 62.A N SER 60.A OG no hydrogen 3.298 N/A CYS 62.A SG ASN 61.A OD1 no hydrogen 3.835 N/A GLU 63.A N ASP 86.A OD2 no hydrogen 2.814 N/A ALA 65.A N ASP 86.A OD1 no hydrogen 2.807 N/A ALA 66.A N GLU 70.A OE1 no hydrogen 2.909 N/A SER 69.A OG ASN 67.A OD1 no hydrogen 2.549 N/A GLU 70.A N ASN 67.A O no hydrogen 2.978 N/A LEU 71.A N ALA 68.A O no hydrogen 3.125 N/A ARG 72.A N GLU 63.A OE1 no hydrogen 2.744 N/A ARG 72.A NE ASP 26.A OD1 no hydrogen 2.776 N/A ARG 72.A NH2 ASP 26.A OD1 no hydrogen 2.943 N/A ARG 72.A NH2 ASP 29.A OD2 no hydrogen 2.792 N/A THR 73.A N GLU 63.A OE2 no hydrogen 2.876 N/A THR 73.A OG1 GLU 70.A O no hydrogen 2.550 N/A LYS 74.A N GLU 63.A OE2 no hydrogen 2.820 N/A LYS 74.A NZ GLU 63.A O no hydrogen 3.450 N/A LYS 74.A NZ GLY 64.A O no hydrogen 2.941 N/A ARG 76.A NH1 ARG 22.A O no hydrogen 2.842 N/A ASP 77.A N SER 60.A O no hydrogen 2.910 N/A GLN 78.A N CYS 62.A O no hydrogen 3.208 N/A GLN 78.A NE2 ARG 76.A O no hydrogen 2.921 N/A PHE 80.A N TRP 48.A O no hydrogen 3.044 N/A GLY 82.A N ASP 79.A OD1 no hydrogen 2.968 N/A CYS 83.A N ASP 79.A O no hydrogen 2.953 N/A LEU 84.A N PHE 80.A O no hydrogen 2.896 N/A SER 85.A N ALA 81.A O no hydrogen 2.955 N/A SER 85.A OG ALA 81.A O no hydrogen 3.085 N/A ASP 86.A N GLY 82.A O no hydrogen 2.999 N/A MET 87.A N CYS 83.A O no hydrogen 2.926 N/A ARG 88.A N LEU 84.A O no hydrogen 2.902 N/A ARG 88.A NE ASP 92.A OD1 no hydrogen 3.407 N/A ARG 88.A NE ASP 92.A OD2 no hydrogen 3.166 N/A ARG 88.A NH1 LYS 128.A O no hydrogen 2.921 N/A ALA 89.A N SER 85.A O no hydrogen 2.922 N/A TRP 90.A N ASP 86.A O no hydrogen 2.894 N/A TRP 90.A NE1 ASP 29.A OD1 no hydrogen 2.813 N/A HIS 91.A N MET 87.A O no hydrogen 2.802 N/A HIS 91.A ND1 HIS 97.A NE2 no hydrogen 2.819 N/A ASP 92.A N ARG 88.A O no hydrogen 2.937 N/A ALA 93.A N ALA 89.A O no hydrogen 3.250 N/A ALA 93.A N TRP 90.A O no hydrogen 3.068 N/A HIS 94.A N HIS 91.A O no hydrogen 3.062 N/A HIS 97.A N HIS 94.A O no hydrogen 3.097 N/A HIS 97.A ND1 ARG 98.A O no hydrogen 2.752 N/A HIS 97.A NE2 HIS 91.A ND1 no hydrogen 2.819 N/A ARG 98.A NE ALA 32.A O no hydrogen 2.869 N/A ARG 98.A NH1 LEU 28.A O no hydrogen 3.015 N/A ARG 98.A NH2 LEU 28.A O no hydrogen 2.738 N/A ARG 98.A NH2 ALA 32.A O no hydrogen 2.869 N/A ILE 100.A N LYS 164.A O no hydrogen 3.144 N/A LEU 101.A N ALA 33.A O no hydrogen 2.901 N/A LEU 102.A N LEU 166.A O no hydrogen 2.782 N/A LYS 103.A N LEU 35.A O no hydrogen 2.916 N/A LYS 103.A NZ ASP 236.A OD1 no hydrogen 3.181 N/A LYS 103.A NZ ASP 236.A OD2 no hydrogen 2.800 N/A ILE 104.A N GLU 168.A O no hydrogen 2.720 N/A GLU 105.A N LEU 37.A O no hydrogen 2.894 N/A MET 106.A N ILE 170.A O no hydrogen 3.072 N/A LYS 107.A N LEU 39.A O no hydrogen 2.831 N/A LYS 107.A NZ GLU 105.A OE2 no hydrogen 2.820 N/A LYS 107.A NZ THR 173.A OG1 no hydrogen 2.858 N/A GLY 109.A N MET 106.A O no hydrogen 2.979 N/A ASN 111.A N ARG 116.A O no hydrogen 2.844 N/A ASN 111.A ND2 SER 41.A O no hydrogen 3.010 N/A GLY 114.A N ASN 111.A O no hydrogen 3.011 N/A GLY 114.A N ASN 111.A OD1 no hydrogen 3.029 N/A GLY 115.A N ALA 112.A O no hydrogen 3.031 N/A ARG 116.A N ASN 111.A O no hydrogen 2.831 N/A ARG 116.A NE SER 41.A O no hydrogen 2.826 N/A ARG 116.A NH1 SER 41.A O no hydrogen 3.014 N/A ARG 116.A NH1 GLY 45.A O no hydrogen 3.015 N/A ARG 116.A NH2 GLY 45.A O no hydrogen 2.895 N/A GLY 117.A N GLU 120.A OE1 no hydrogen 2.822 N/A PHE 121.A N GLY 117.A O no hydrogen 2.946 N/A ASP 122.A N PRO 118.A O no hydrogen 2.955 N/A ALA 123.A N ALA 119.A O no hydrogen 2.995 N/A LEU 124.A N GLU 120.A O no hydrogen 3.030 N/A ILE 125.A N PHE 121.A O no hydrogen 3.156 N/A ARG 126.A N ASP 122.A O no hydrogen 2.862 N/A ARG 126.A NH1 GLN 204.A O no hydrogen 2.959 N/A GLN 127.A N ALA 123.A O no hydrogen 2.971 N/A LYS 128.A N LEU 124.A O no hydrogen 2.977 N/A LYS 128.A NZ SER 85.A OG no hydrogen 2.739 N/A LEU 129.A N ILE 125.A O no hydrogen 2.848 N/A GLY 130.A N ARG 126.A O no hydrogen 2.919 N/A ALA 132.A N LEU 129.A O no hydrogen 2.999 N/A VAL 133.A N GLY 130.A O no hydrogen 3.304 N/A TYR 134.A N PHE 165.A O no hydrogen 2.916 N/A GLY 135.A N ASP 138.A OD2 no hydrogen 2.858 N/A LEU 139.A N GLY 135.A O no hydrogen 3.114 N/A THR 140.A N PRO 136.A O no hydrogen 2.873 N/A THR 140.A OG1 PRO 136.A O no hydrogen 2.763 N/A GLY 141.A N GLY 137.A O no hydrogen 3.134 N/A HIS 143.A N THR 140.A O no hydrogen 2.978 N/A HIS 143.A ND1 GLU 148.A OE2 no hydrogen 2.827 N/A ALA 144.A N GLU 148.A OE2 no hydrogen 3.247 N/A ASP 147.A N PRO 230.A O no hydrogen 2.933 N/A GLU 148.A N THR 145.A OG1 no hydrogen 3.058 N/A ALA 149.A N THR 145.A O no hydrogen 3.080 N/A VAL 150.A N ALA 146.A O no hydrogen 2.869 N/A ARG 151.A N ASP 147.A O no hydrogen 3.038 N/A ALA 152.A N GLU 148.A O no hydrogen 3.186 N/A GLY 153.A N ALA 149.A O no hydrogen 2.970 N/A GLY 154.A N VAL 150.A O no hydrogen 2.846 N/A TRP 155.A NE1 HIS 256.A O no hydrogen 2.779 N/A SER 157.A OG ASP 160.A OD2 no hydrogen 2.588 N/A ARG 158.A N THR 2.A O no hydrogen 2.979 N/A ASP 160.A N SER 157.A OG no hydrogen 2.990 N/A LEU 161.A N SER 157.A O no hydrogen 3.212 N/A LEU 161.A N ARG 158.A O no hydrogen 3.081 N/A ALA 162.A N ALA 159.A O no hydrogen 3.213 N/A GLY 163.A N HIS 97.A O no hydrogen 2.672 N/A LYS 164.A N LEU 161.A O no hydrogen 3.126 N/A LYS 164.A NZ ASP 131.A O no hydrogen 2.754 N/A PHE 165.A N ALA 132.A O no hydrogen 2.788 N/A LEU 166.A N ILE 100.A O no hydrogen 2.923 N/A GLU 168.A N LEU 102.A O no hydrogen 2.944 N/A LEU 169.A N PHE 208.A O no hydrogen 2.968 N/A ILE 170.A N ILE 104.A O no hydrogen 2.953 N/A GLY 172.A N GLU 175.A OE2 no hydrogen 2.906 N/A THR 173.A N GLU 105.A OE2 no hydrogen 3.091 N/A VAL 174.A N LYS 107.A O no hydrogen 3.005 N/A GLU 175.A N LYS 107.A O no hydrogen 3.235 N/A GLU 176.A N GLY 172.A O no hydrogen 3.135 N/A LYS 177.A N VAL 174.A O no hydrogen 3.029 N/A ASN 178.A N GLU 175.A O no hydrogen 3.360 N/A PHE 180.A N ASN 178.A OD1 no hydrogen 2.763 N/A LYS 182.A NZ PHE 110.A O no hydrogen 2.960 N/A THR 185.A N GLU 175.A OE1 no hydrogen 3.089 N/A THR 185.A OG1 GLU 175.A OE1 no hydrogen 3.387 N/A THR 185.A OG1 GLU 175.A OE2 no hydrogen 2.560 N/A VAL 187.A N ASP 186.A OD1 no hydrogen 2.806 N/A GLU 188.A N TRP 184.A O no hydrogen 2.931 N/A TYR 189.A N THR 185.A O no hydrogen 2.896 N/A TYR 189.A OH ASP 122.A OD1 no hydrogen 2.651 N/A ALA 190.A N ASP 186.A O no hydrogen 2.927 N/A GLY 191.A N VAL 187.A O no hydrogen 2.910 N/A HIS 192.A N GLU 188.A O no hydrogen 3.076 N/A HIS 192.A NE2 ASP 122.A OD2 no hydrogen 2.688 N/A LEU 193.A N TYR 189.A O no hydrogen 2.967 N/A LYS 194.A N ALA 190.A O no hydrogen 2.966 N/A LYS 194.A NZ ASP 195.A OD1 no hydrogen 3.317 N/A ASP 195.A N GLY 191.A O no hydrogen 2.898 N/A LEU 196.A N HIS 192.A O no hydrogen 2.861 N/A ALA 197.A N LEU 193.A O no hydrogen 2.874 N/A ALA 198.A N LYS 194.A O no hydrogen 3.053 N/A GLN 199.A N ASP 195.A O no hydrogen 3.152 N/A GLN 199.A N LEU 196.A O no hydrogen 2.992 N/A GLY 200.A N ALA 197.A O no hydrogen 3.040 N/A LYS 201.A N LEU 196.A O no hydrogen 2.751 N/A GLN 204.A N LYS 201.A O no hydrogen 3.227 N/A SER 205.A N LEU 202.A O no hydrogen 3.029 N/A SER 205.A OG LEU 202.A O no hydrogen 2.757 N/A THR 206.A N ASP 122.A OD1 no hydrogen 3.214 N/A THR 206.A N TYR 189.A OH no hydrogen 3.356 N/A THR 206.A OG1 ASP 122.A OD1 no hydrogen 2.779 N/A ALA 207.A N TYR 189.A OH no hydrogen 3.187 N/A PHE 208.A N PHE 167.A O no hydrogen 2.824 N/A ALA 210.A N LEU 169.A O no hydrogen 2.911 N/A VAL 211.A N VAL 234.A O no hydrogen 2.941 N/A GLY 213.A N ASP 236.A O no hydrogen 2.759 N/A ARG 220.A N ASP 218.A OD1 no hydrogen 2.901 N/A ARG 220.A NE ASP 218.A OD1 no hydrogen 2.902 N/A ARG 220.A NE ASP 218.A OD2 no hydrogen 3.462 N/A ARG 220.A NH1 ASP 147.A OD1 no hydrogen 2.954 N/A ARG 220.A NH1 PHE 232.A O no hydrogen 2.937 N/A ARG 220.A NH1 TYR 257.A OH no hydrogen 3.359 N/A ARG 220.A NH2 ASP 218.A OD2 no hydrogen 2.922 N/A ARG 220.A NH2 TYR 257.A OH no hydrogen 2.935 N/A GLU 221.A N ASP 218.A O no hydrogen 3.048 N/A ARG 222.A N PRO 219.A O no hydrogen 3.170 N/A ARG 222.A NE PRO 219.A O no hydrogen 3.242 N/A ARG 222.A NH1 HIS 212.A O no hydrogen 2.855 N/A ARG 222.A NH2 GLY 213.A O no hydrogen 3.049 N/A TYR 223.A N ARG 220.A O no hydrogen 3.039 N/A TYR 223.A OH ASP 186.A OD2 no hydrogen 2.715 N/A ALA 227.A N ASP 225.A OD1 no hydrogen 2.938 N/A LEU 228.A N ASP 225.A O no hydrogen 3.082 N/A ARG 229.A N PRO 226.A O no hydrogen 3.175 N/A ARG 229.A NE TYR 223.A O no hydrogen 2.989 N/A ARG 229.A NH2 TYR 223.A O no hydrogen 2.788 N/A TRP 231.A N LEU 228.A O no hydrogen 3.112 N/A PHE 232.A N ARG 229.A O no hydrogen 3.127 N/A PHE 235.A N LEU 258.A O no hydrogen 2.899 N/A ASP 236.A N VAL 211.A O no hydrogen 2.972 N/A GLY 237.A N ILE 260.A O no hydrogen 2.949 N/A ALA 239.A N THR 262.A O no hydrogen 2.912 N/A THR 241.A N ASP 238.A OD2 no hydrogen 3.021 N/A THR 241.A OG1 ASP 238.A OD2 no hydrogen 2.843 N/A TYR 242.A N ASP 238.A O no hydrogen 3.010 N/A LEU 243.A N ALA 239.A O no hydrogen 3.063 N/A LEU 243.A N ALA 240.A O no hydrogen 3.144 N/A ASN 244.A N THR 241.A O no hydrogen 3.089 N/A SER 246.A N ASN 244.A OD1 no hydrogen 2.979 N/A SER 246.A OG ASN 244.A OD1 no hydrogen 2.634 N/A THR 249.A OG1 ALA 291.A O no hydrogen 2.662 N/A SER 250.A N ASP 248.A OD1 no hydrogen 3.088 N/A SER 250.A OG ASP 248.A OD1 no hydrogen 2.665 N/A SER 250.A OG ASP 248.A OD2 no hydrogen 3.459 N/A TRP 251.A N ASP 248.A O no hydrogen 3.349 N/A TYR 252.A N THR 249.A O no hydrogen 3.205 N/A THR 254.A N SER 250.A O no hydrogen 2.913 N/A THR 254.A OG1 SER 250.A O no hydrogen 3.116 N/A ARG 255.A N TRP 251.A O no hydrogen 3.313 N/A ARG 255.A NH1 TYR 257.A OH no hydrogen 3.081 N/A HIS 256.A N ASP 253.A O no hydrogen 3.111 N/A TYR 257.A N TYR 252.A O no hydrogen 2.930 N/A TYR 257.A OH ASP 147.A OD1 no hydrogen 2.537 N/A LEU 258.A N VAL 233.A O no hydrogen 3.042 N/A LEU 259.A N SER 294.A OG no hydrogen 3.025 N/A ILE 260.A N PHE 235.A O no hydrogen 2.785 N/A MET 261.A N PHE 295.A O no hydrogen 2.875 N/A THR 262.A N GLY 237.A O no hydrogen 2.872 N/A THR 262.A OG1 GLY 237.A O no hydrogen 3.224 N/A ALA 264.A N THR 297.A O no hydrogen 2.894 N/A ASN 266.A N ASP 263.A O no hydrogen 2.940 N/A VAL 267.A N ALA 264.A O no hydrogen 3.426 N/A ILE 271.A N HIS 265.A O no hydrogen 2.967 N/A THR 274.A N ASP 272.A OD2 no hydrogen 2.944 N/A HIS 275.A N ASP 272.A OD2 no hydrogen 2.626 N/A THR 277.A N GLU 280.A OE1 no hydrogen 3.041 N/A GLU 280.A N THR 277.A OG1 no hydrogen 3.032 N/A ALA 281.A N THR 277.A O no hydrogen 3.040 N/A LEU 282.A N GLU 278.A O no hydrogen 2.916 N/A ALA 283.A N ALA 279.A O no hydrogen 3.029 N/A ARG 284.A N GLU 280.A O no hydrogen 3.047 N/A ARG 284.A NE GLN 287.A OE1 no hydrogen 3.146 N/A ARG 284.A NH1 ALA 264.A O no hydrogen 2.930 N/A ARG 284.A NH1 HIS 265.A O no hydrogen 3.317 N/A ARG 284.A NH2 PRO 269.A O no hydrogen 2.884 N/A VAL 285.A N ALA 281.A O no hydrogen 2.916 N/A ARG 286.A N LEU 282.A O no hydrogen 2.979 N/A GLN 287.A N ALA 283.A O no hydrogen 2.917 N/A LEU 288.A N ARG 284.A O no hydrogen 2.988 N/A ALA 289.A N VAL 285.A O no hydrogen 2.853 N/A ALA 290.A N ARG 286.A O no hydrogen 3.022 N/A ALA 291.A N GLN 287.A O no hydrogen 3.079 N/A HIS 292.A N ALA 289.A O no hydrogen 2.915 N/A HIS 292.A ND1 ASP 253.A OD2 no hydrogen 2.750 N/A ALA 293.A N LEU 288.A O no hydrogen 2.965 N/A SER 294.A N LEU 259.A O no hydrogen 2.726 N/A PHE 295.A N LEU 259.A O no hydrogen 3.113 N/A ALA 296.A N SER 9.A O no hydrogen 2.913 N/A THR 297.A N MET 261.A O no hydrogen 2.946 N/A ALA 298.A N GLY 11.A O no hydrogen 3.319 N/A ASP 299.A N GLY 273.A O no hydrogen 2.865 N/A TRP 300.A NE1 ASP 272.A O no hydrogen 3.065 N/A TYR 301.A N ASP 299.A O no hydrogen 2.834 N/A LEU 303.A N TRP 300.A O no hydrogen 2.948 N/A SER 305.A OG GLU 278.A OE2 no hydrogen 2.810 N/A LEU 307.A N LEU 303.A O no hydrogen 2.998 N/A LYS 308.A N PRO 304.A O no hydrogen 3.065 N/A LYS 308.A NZ SER 30.A O no hydrogen 2.775 N/A LYS 308.A NZ PRO 304.A O no hydrogen 3.290 N/A THR 309.A N VAL 306.A O no hydrogen 2.962 N/A THR 309.A OG1 SER 305.A O no hydrogen 3.442 N/A THR 309.A OG1 VAL 306.A O no hydrogen 2.878 N/A VAL 311.A N THR 8.A O no hydrogen 2.937 N/A ARG 313.A N THR 6.A O no hydrogen 2.935 N/A ARG 313.A NE HIS 292.A O no hydrogen 2.793 N/A ARG 313.A NH1 GLY 5.A O no hydrogen 2.846 N/A ARG 313.A NH1 TYR 257.A O no hydrogen 2.897 N/A ARG 313.A NH2 TYR 257.A O no hydrogen 2.889 N/A ARG 313.A NH2 HIS 292.A O no hydrogen 3.024 N/A GLY 314.A N ALA 289.A O no hydrogen 2.801 N/A