Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3h78_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 1.A N GLY 171.A O no hydrogen 3.072 N/A ASN 2.A N SER 173.A O no hydrogen 2.879 N/A ASN 2.A ND2 LEU 174.A O no hydrogen 3.113 N/A ASN 2.A ND2 ASP 176.A O no hydrogen 2.789 N/A ILE 4.A N SER 169.A O no hydrogen 2.832 N/A LEU 5.A N TYR 326.A OH no hydrogen 2.785 N/A ALA 6.A N VAL 167.A O no hydrogen 2.751 N/A GLY 9.A N ALA 165.A O no hydrogen 2.942 N/A PHE 10.A N GLN 61.A OE1 no hydrogen 2.905 N/A SER 11.A N ALA 163.A O no hydrogen 2.883 N/A ARG 15.A NE GLU 46.A OE2 no hydrogen 2.870 N/A ARG 15.A NH2 VAL 45.A O no hydrogen 2.909 N/A GLN 16.A NE2 THR 41.A OG1 no hydrogen 3.239 N/A VAL 17.A N ARG 42.A O no hydrogen 2.691 N/A SER 18.A N ASP 21.A OD2 no hydrogen 2.853 N/A ASN 19.A ND2 ASP 30.A OD1 no hydrogen 2.839 N/A ASN 19.A ND2 VAL 39.A O no hydrogen 2.948 N/A ASP 21.A N SER 18.A O no hydrogen 3.168 N/A ASP 21.A N SER 18.A OG no hydrogen 3.152 N/A LEU 22.A N ASN 19.A O no hydrogen 2.992 N/A VAL 23.A N ASN 19.A O no hydrogen 3.229 N/A ARG 25.A N LEU 22.A O no hydrogen 3.066 N/A ILE 26.A N LEU 22.A O no hydrogen 2.998 N/A GLU 31.A N GLU 31.A OE1 no hydrogen 2.744 N/A PHE 32.A N SER 29.A OG no hydrogen 3.138 N/A ILE 33.A N SER 29.A O no hydrogen 3.048 N/A VAL 34.A N ASP 30.A O no hydrogen 3.001 N/A GLU 35.A N GLU 31.A O no hydrogen 2.968 N/A ARG 36.A N PHE 32.A O no hydrogen 2.883 N/A ARG 36.A NE GLU 35.A OE1 no hydrogen 3.227 N/A ARG 36.A NE GLU 35.A OE2 no hydrogen 3.146 N/A THR 37.A N ILE 33.A O no hydrogen 2.873 N/A THR 37.A OG1 ILE 33.A O no hydrogen 2.714 N/A GLY 38.A N VAL 34.A O no hydrogen 2.917 N/A VAL 39.A N THR 37.A OG1 no hydrogen 3.043 N/A ARG 40.A N ASP 283.A O no hydrogen 2.874 N/A THR 41.A N ASP 283.A O no hydrogen 3.004 N/A THR 41.A OG1 ARG 284.A O no hydrogen 2.706 N/A ARG 42.A N VAL 17.A O no hydrogen 3.020 N/A ARG 42.A NH1 ASN 19.A OD1 no hydrogen 2.611 N/A ARG 42.A NH1 ILE 157.A O no hydrogen 2.825 N/A ARG 42.A NH2 VAL 17.A O no hydrogen 3.177 N/A ARG 42.A NH2 ASN 19.A OD1 no hydrogen 2.767 N/A HIS 44.A N ARG 15.A O no hydrogen 3.033 N/A HIS 44.A NE2 LEU 159.A O no hydrogen 2.872 N/A VAL 45.A N ASP 161.A OD2 no hydrogen 2.904 N/A GLU 46.A N GLN 49.A OE1 no hydrogen 2.976 N/A GLN 49.A N GLU 46.A O no hydrogen 2.966 N/A SER 52.A N ASP 84.A OD1 no hydrogen 2.991 N/A SER 52.A OG ASP 84.A OD1 no hydrogen 3.424 N/A SER 52.A OG ASP 84.A OD2 no hydrogen 2.618 N/A ALA 53.A N ALA 50.A O no hydrogen 3.074 N/A LEU 54.A N VAL 51.A O no hydrogen 2.949 N/A MET 55.A N VAL 51.A O no hydrogen 3.000 N/A VAL 56.A N SER 52.A O no hydrogen 2.983 N/A ALA 58.A N LEU 54.A O no hydrogen 3.259 N/A ALA 59.A N MET 55.A O no hydrogen 2.924 N/A ARG 60.A N VAL 56.A O no hydrogen 2.927 N/A ARG 60.A NH2 LEU 97.A O no hydrogen 2.813 N/A GLN 61.A N PRO 57.A O no hydrogen 2.904 N/A ALA 62.A N ALA 58.A O no hydrogen 3.108 N/A ILE 63.A N ALA 59.A O no hydrogen 2.900 N/A GLU 64.A N ARG 60.A O no hydrogen 2.956 N/A ALA 65.A N GLN 61.A O no hydrogen 2.852 N/A ALA 66.A N ALA 62.A O no hydrogen 3.066 N/A ALA 66.A N ILE 63.A O no hydrogen 3.203 N/A GLY 67.A N GLU 64.A O no hydrogen 3.008 N/A LEU 68.A N ILE 63.A O no hydrogen 3.152 N/A LEU 69.A N ASP 72.A OD2 no hydrogen 2.760 N/A GLU 71.A N GLU 71.A OE1 no hydrogen 2.761 N/A ASP 72.A N LEU 69.A O no hydrogen 2.881 N/A ILE 73.A N PRO 70.A O no hydrogen 3.153 N/A ASP 74.A N HIS 133.A O no hydrogen 2.801 N/A LEU 76.A N PRO 104.A O no hydrogen 3.218 N/A LEU 77.A N LEU 135.A O no hydrogen 2.860 N/A VAL 78.A N LEU 106.A O no hydrogen 2.973 N/A ASN 79.A N VAL 137.A O no hydrogen 2.843 N/A THR 80.A OG1 GLY 139.A O no hydrogen 2.785 N/A THR 80.A OG1 GLU 140.A OE1 no hydrogen 3.154 N/A LEU 81.A N GLU 140.A OE1 no hydrogen 2.951 N/A SER 82.A N THR 80.A OG1 no hydrogen 2.967 N/A SER 82.A OG GLU 140.A OE1 no hydrogen 2.956 N/A ASP 84.A N GLN 90.A OE1 no hydrogen 2.891 N/A HIS 86.A ND1 ASP 87.A OD2 no hydrogen 2.791 N/A GLN 90.A N ASP 107.A OD2 no hydrogen 2.813 N/A GLN 90.A NE2 ASP 84.A OD1 no hydrogen 2.961 N/A ALA 91.A N ASP 107.A OD1 no hydrogen 2.766 N/A CYS 92.A N SER 89.A OG no hydrogen 2.959 N/A CYS 92.A SG SER 89.A OG no hydrogen 3.217 N/A LEU 93.A N SER 89.A O no hydrogen 3.114 N/A ILE 94.A N GLN 90.A O no hydrogen 2.967 N/A GLN 95.A N ALA 91.A O no hydrogen 2.978 N/A GLN 95.A NE2 ARG 101.A O no hydrogen 2.899 N/A LEU 98.A N ILE 94.A O no hydrogen 2.930 N/A LEU 98.A N GLN 95.A O no hydrogen 3.196 N/A GLY 99.A N PRO 96.A O no hydrogen 3.154 N/A LEU 100.A N GLN 95.A O no hydrogen 3.274 N/A ARG 101.A NE GLU 71.A O no hydrogen 2.671 N/A ARG 101.A NH2 GLU 71.A O no hydrogen 3.181 N/A ARG 101.A NH2 ASP 74.A OD1 no hydrogen 3.118 N/A LEU 106.A N LEU 76.A O no hydrogen 2.996 N/A ILE 108.A N VAL 78.A O no hydrogen 2.798 N/A SER 113.A N ALA 110.A O no hydrogen 3.160 N/A SER 113.A OG THR 314.A OG1 no hydrogen 3.050 N/A SER 113.A OG THR 320.A OG1 no hydrogen 3.040 N/A GLY 114.A N GLN 111.A O no hydrogen 3.086 N/A TYR 117.A N SER 113.A O no hydrogen 3.005 N/A TYR 117.A OH GLY 184.A O no hydrogen 2.706 N/A GLY 118.A N GLY 114.A O no hydrogen 2.805 N/A LEU 119.A N LEU 115.A O no hydrogen 2.841 N/A GLN 120.A N LEU 116.A O no hydrogen 2.908 N/A MET 121.A N TYR 117.A O no hydrogen 3.075 N/A ALA 122.A N GLY 118.A O no hydrogen 2.895 N/A ARG 123.A N LEU 119.A O no hydrogen 2.783 N/A ARG 123.A NH1 GLN 120.A OE1 no hydrogen 2.971 N/A GLY 124.A N GLN 120.A O no hydrogen 3.007 N/A GLN 125.A N MET 121.A O no hydrogen 3.092 N/A ILE 126.A N ALA 122.A O no hydrogen 2.935 N/A LEU 127.A N ARG 123.A O no hydrogen 2.850 N/A ALA 128.A N GLY 124.A O no hydrogen 3.000 N/A GLY 129.A N ILE 126.A O no hydrogen 3.044 N/A LEU 130.A N GLN 125.A O no hydrogen 2.805 N/A ARG 132.A N ASP 74.A OD2 no hydrogen 2.775 N/A HIS 133.A N ASP 74.A OD2 no hydrogen 3.091 N/A HIS 133.A ND1 SER 169.A OG no hydrogen 2.810 N/A VAL 134.A N VAL 168.A O no hydrogen 2.818 N/A LEU 135.A N LEU 75.A O no hydrogen 2.921 N/A VAL 136.A N VAL 166.A O no hydrogen 2.853 N/A VAL 137.A N LEU 77.A O no hydrogen 2.918 N/A CYS 138.A N GLY 164.A O no hydrogen 2.928 N/A GLY 139.A N ASN 79.A O no hydrogen 3.231 N/A GLU 140.A N GLY 162.A O no hydrogen 2.902 N/A VAL 141.A N SER 82.A OG no hydrogen 2.784 N/A SER 143.A N ASP 161.A OD1 no hydrogen 2.839 N/A SER 143.A OG ASP 161.A OD1 no hydrogen 3.383 N/A SER 143.A OG ASP 161.A OD2 no hydrogen 2.682 N/A LYS 144.A NZ PRO 47.A O no hydrogen 2.835 N/A LYS 144.A NZ GLN 49.A O no hydrogen 2.777 N/A ARG 145.A N LEU 142.A O no hydrogen 2.805 N/A ARG 145.A NH1 LEU 81.A O no hydrogen 2.951 N/A ARG 145.A NH2 THR 195.A OG1 no hydrogen 2.798 N/A SER 149.A N ASP 147.A OD1 no hydrogen 3.031 N/A SER 149.A OG ASP 147.A OD1 no hydrogen 2.634 N/A SER 149.A OG ASP 147.A OD2 no hydrogen 3.291 N/A ARG 151.A NH1 GLU 213.A O no hydrogen 2.933 N/A GLY 152.A N SER 149.A O no hydrogen 3.049 N/A ARG 153.A N SER 149.A O no hydrogen 2.993 N/A ARG 153.A NH1 ASN 27.A O no hydrogen 2.829 N/A ASN 154.A ND2 MET 220.A O no hydrogen 3.085 N/A LEU 155.A N GLY 152.A O no hydrogen 3.053 N/A SER 156.A N GLY 152.A O no hydrogen 2.992 N/A SER 156.A OG ASP 147.A O no hydrogen 2.918 N/A SER 156.A OG GLY 152.A O no hydrogen 3.385 N/A LEU 158.A N LEU 155.A O no hydrogen 2.883 N/A GLY 160.A N ASN 287.A O no hydrogen 2.956 N/A ASP 161.A N TYR 43.A O no hydrogen 3.049 N/A GLY 162.A N GLU 140.A O no hydrogen 3.069 N/A ALA 163.A N SER 11.A O no hydrogen 2.983 N/A GLY 164.A N CYS 138.A O no hydrogen 2.868 N/A ALA 165.A N GLY 9.A O no hydrogen 2.849 N/A VAL 166.A N VAL 136.A O no hydrogen 2.870 N/A VAL 167.A N GLY 7.A O no hydrogen 2.839 N/A VAL 168.A N VAL 134.A O no hydrogen 2.819 N/A SER 169.A N ILE 4.A O no hydrogen 2.914 N/A SER 169.A OG HIS 133.A ND1 no hydrogen 2.810 N/A ALA 170.A N ARG 132.A O no hydrogen 3.156 N/A SER 173.A OG ASP 176.A OD1 no hydrogen 3.291 N/A GLU 175.A N SER 173.A OG no hydrogen 2.824 N/A ASP 176.A N SER 173.A OG no hydrogen 3.318 N/A GLY 177.A N ARG 327.A O no hydrogen 2.725 N/A LEU 178.A N PRO 3.A O no hydrogen 2.852 N/A LEU 179.A N LEU 325.A O no hydrogen 2.925 N/A ASP 180.A N LEU 325.A O no hydrogen 3.417 N/A LEU 181.A N ASP 180.A OD1 no hydrogen 2.800 N/A ARG 182.A N ALA 323.A O no hydrogen 2.854 N/A ARG 182.A NE ASP 180.A OD2 no hydrogen 2.771 N/A ARG 182.A NH2 ASP 180.A OD2 no hydrogen 3.034 N/A GLY 184.A N TRP 321.A O no hydrogen 3.054 N/A ASP 186.A N ALA 319.A O no hydrogen 2.843 N/A ASN 188.A N ASP 186.A OD1 no hydrogen 3.025 N/A ASN 188.A ND2 ASP 186.A OD1 no hydrogen 2.902 N/A TYR 189.A N ASP 186.A O no hydrogen 3.030 N/A PHE 190.A N GLY 187.A O no hydrogen 3.071 N/A LEU 192.A N TYR 189.A O no hydrogen 2.998 N/A MET 194.A N LEU 219.A O no hydrogen 3.145 N/A ALA 197.A N GLY 215.A O no hydrogen 2.912 N/A GLY 199.A N PHE 205.A O no hydrogen 3.179 N/A VAL 210.A N ASP 207.A OD1 no hydrogen 2.912 N/A LEU 211.A N ASP 207.A O no hydrogen 3.081 N/A ARG 212.A N GLU 208.A O no hydrogen 2.878 N/A ARG 212.A NH1 ASN 209.A OD1 no hydrogen 2.784 N/A ARG 212.A NH2 ASN 209.A OD1 no hydrogen 3.492 N/A GLU 213.A N ASN 209.A O no hydrogen 3.086 N/A GLY 214.A N LEU 211.A O no hydrogen 2.941 N/A GLY 215.A N VAL 210.A O no hydrogen 2.930 N/A GLU 217.A N GLY 214.A O no hydrogen 3.163 N/A LEU 219.A N MET 194.A O no hydrogen 2.816 N/A ARG 221.A N LEU 192.A O no hydrogen 2.791 N/A ARG 221.A NH1 ASP 191.A OD1 no hydrogen 2.651 N/A ARG 223.A NE GLU 227.A OE2 no hydrogen 2.787 N/A MET 225.A N ARG 221.A O no hydrogen 3.028 N/A PHE 226.A N GLY 222.A O no hydrogen 2.916 N/A GLU 227.A N ARG 223.A O no hydrogen 2.999 N/A HIS 228.A N PRO 224.A O no hydrogen 2.959 N/A HIS 228.A ND1 TYR 315.A OH no hydrogen 2.584 N/A ALA 229.A N MET 225.A O no hydrogen 2.801 N/A SER 230.A N PHE 226.A O no hydrogen 3.032 N/A SER 230.A OG PHE 226.A O no hydrogen 2.915 N/A SER 230.A OG GLU 227.A O no hydrogen 3.229 N/A GLN 231.A N GLU 227.A O no hydrogen 3.039 N/A THR 232.A N HIS 228.A O no hydrogen 2.865 N/A THR 232.A OG1 HIS 228.A O no hydrogen 2.764 N/A LEU 233.A N ALA 229.A O no hydrogen 2.923 N/A VAL 234.A N SER 230.A O no hydrogen 3.047 N/A ARG 235.A N GLN 231.A O no hydrogen 3.002 N/A ILE 236.A N THR 232.A O no hydrogen 2.920 N/A ALA 237.A N LEU 233.A O no hydrogen 3.113 N/A GLY 238.A N VAL 234.A O no hydrogen 3.125 N/A GLU 239.A N ARG 235.A O no hydrogen 2.951 N/A MET 240.A N ILE 236.A O no hydrogen 3.002 N/A LEU 241.A N ALA 237.A O no hydrogen 3.092 N/A ALA 242.A N GLY 238.A O no hydrogen 2.927 N/A ALA 243.A N GLU 239.A O no hydrogen 3.002 N/A HIS 244.A N LEU 241.A O no hydrogen 3.113 N/A HIS 244.A NE2 ASP 180.A OD2 no hydrogen 2.834 N/A GLU 245.A N ALA 242.A O no hydrogen 3.018 N/A LEU 246.A N LEU 241.A O no hydrogen 2.883 N/A THR 247.A N ASP 250.A OD2 no hydrogen 2.803 N/A ASP 249.A N THR 247.A OG1 no hydrogen 3.290 N/A ASP 250.A N THR 247.A O no hydrogen 2.905 N/A ILE 251.A N LEU 248.A O no hydrogen 2.968 N/A ASP 252.A N ARG 309.A O no hydrogen 2.887 N/A HIS 253.A N ARG 309.A O no hydrogen 3.348 N/A HIS 253.A NE2 GLN 308.A OE1 no hydrogen 2.851 N/A VAL 254.A N LYS 277.A O no hydrogen 2.845 N/A ILE 255.A N LEU 311.A O no hydrogen 2.893 N/A CYS 256.A SG.A HIS 257.A O no hydrogen 3.490 N/A CYS 256.A SG.A LEU 313.A O no hydrogen 3.707 N/A HIS 257.A N LEU 313.A O no hydrogen 2.919 N/A ASN 260.A ND2 ARG 36.A O no hydrogen 3.401 N/A LEU 261.A N THR 37.A O no hydrogen 2.729 N/A ARG 262.A NE GLU 35.A O no hydrogen 3.007 N/A ARG 262.A NH1 ASP 265.A OD2 no hydrogen 2.974 N/A ARG 262.A NH2 VAL 34.A O no hydrogen 2.841 N/A ASP 265.A N LEU 261.A O no hydrogen 2.726 N/A ALA 266.A N ARG 262.A O no hydrogen 3.168 N/A VAL 267.A N ILE 263.A O no hydrogen 3.029 N/A GLN 268.A N LEU 264.A O no hydrogen 2.865 N/A GLN 268.A NE2 ILE 273.A O no hydrogen 2.975 N/A GLU 269.A N ASP 265.A O no hydrogen 2.858 N/A GLN 270.A N ALA 266.A O no hydrogen 2.990 N/A LEU 271.A N VAL 267.A O no hydrogen 3.005 N/A GLY 272.A N GLN 268.A O no hydrogen 2.777 N/A ILE 273.A N GLN 268.A O no hydrogen 3.110 N/A LYS 277.A N PRO 274.A O no hydrogen 3.000 N/A LYS 277.A NZ LEU 248.A O no hydrogen 2.904 N/A LYS 277.A NZ ILE 251.A O no hydrogen 2.781 N/A PHE 278.A N GLN 275.A O no hydrogen 3.130 N/A ALA 279.A N VAL 254.A O no hydrogen 3.226 N/A THR 281.A OG1 THR 296.A OG1.B no hydrogen 2.746 N/A ARG 284.A N THR 281.A O no hydrogen 2.946 N/A LEU 285.A N THR 281.A O no hydrogen 2.846 N/A GLY 286.A N VAL 282.A O no hydrogen 2.953 N/A ASN 287.A N LEU 158.A O no hydrogen 2.784 N/A ASN 287.A ND2 PRO 259.A O no hydrogen 3.177 N/A MET 288.A N SER 292.A OG no hydrogen 2.965 N/A ALA 289.A N ASN 287.A OD1 no hydrogen 2.888 N/A SER 290.A OG ASN 79.A O no hydrogen 3.484 N/A SER 290.A OG ASN 79.A OD1 no hydrogen 3.062 N/A SER 290.A OG GLU 140.A OE2 no hydrogen 2.639 N/A ALA 291.A N MET 288.A O no hydrogen 3.009 N/A SER 292.A N ALA 289.A O no hydrogen 3.007 N/A VAL 295.A N ALA 291.A O no hydrogen 2.908 N/A THR 296.A N SER 292.A O no hydrogen 3.036 N/A THR 296.A OG1.B THR 281.A OG1 no hydrogen 2.746 N/A THR 296.A OG1.B SER 292.A O no hydrogen 2.701 N/A LEU 297.A N THR 293.A O no hydrogen 2.881 N/A ALA 298.A N PRO 294.A O no hydrogen 2.848 N/A MET 299.A N VAL 295.A O no hydrogen 2.844 N/A PHE 300.A N THR 296.A O no hydrogen 2.930 N/A TRP 301.A N ALA 298.A O no hydrogen 3.333 N/A ASP 303.A N PHE 300.A O no hydrogen 2.856 N/A ILE 304.A N TRP 301.A O no hydrogen 2.902 N/A GLN 305.A N GLN 308.A OE1 no hydrogen 2.811 N/A GLY 307.A N LYS 328.A O no hydrogen 2.636 N/A GLN 308.A N GLN 305.A O no hydrogen 2.921 N/A ARG 309.A N ASP 252.A OD2 no hydrogen 2.881 N/A ARG 309.A NH1 ASP 250.A O no hydrogen 3.347 N/A VAL 310.A N TYR 326.A O no hydrogen 2.682 N/A LEU 311.A N HIS 253.A O no hydrogen 2.900 N/A VAL 312.A N ALA 324.A O no hydrogen 2.928 N/A LEU 313.A N ILE 255.A O no hydrogen 2.881 N/A THR 314.A N GLY 322.A O no hydrogen 2.871 N/A THR 314.A OG1 SER 113.A OG no hydrogen 3.050 N/A TYR 315.A OH HIS 228.A ND1 no hydrogen 2.584 N/A GLY 316.A N THR 320.A O no hydrogen 2.808 N/A ALA 319.A N ASP 186.A O no hydrogen 3.036 N/A THR 320.A N GLY 316.A O no hydrogen 3.092 N/A THR 320.A OG1 ALA 110.A O no hydrogen 2.798 N/A THR 320.A OG1 SER 113.A OG no hydrogen 3.040 N/A TRP 321.A N GLY 184.A O no hydrogen 2.930 N/A GLY 322.A N THR 314.A O no hydrogen 3.003 N/A ALA 323.A N ARG 182.A O no hydrogen 2.951 N/A ALA 324.A N VAL 312.A O no hydrogen 2.889 N/A LEU 325.A N ASP 180.A O no hydrogen 2.982 N/A TYR 326.A N VAL 310.A O no hydrogen 2.908 N/A ARG 327.A N GLY 177.A O no hydrogen 2.891 N/A ARG 327.A NE GLY 307.A O no hydrogen 2.872 N/A LYS 328.A N GLN 308.A O no hydrogen 2.975 N/A LYS 328.A NZ ILE 304.A O no hydrogen 2.741 N/A