Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3hax_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N ASP 6.A OD2 no hydrogen 3.109 N/A ASP 6.A N LEU 3.A O no hydrogen 2.877 N/A ARG 9.A NH2 HIS 242.A O no hydrogen 2.823 N/A LEU 12.A N LEU 270.A O no hydrogen 2.714 N/A LYS 14.A N ALA 268.A O no hydrogen 2.937 N/A LYS 14.A NZ MET 302.A O no hydrogen 2.897 N/A LYS 14.A NZ LEU 303.A O no hydrogen 2.934 N/A LYS 14.A NZ LYS 305.A O no hydrogen 2.759 N/A ASP 15.A N ALA 268.A O no hydrogen 2.977 N/A ASN 17.A N ASP 15.A OD1 no hydrogen 3.283 N/A THR 20.A OG1 ASP 250.A OD1 no hydrogen 2.812 N/A THR 20.A OG1 ASP 250.A OD2 no hydrogen 3.254 N/A ASN 21.A N ASP 250.A OD2 no hydrogen 2.738 N/A ASP 23.A N ASN 21.A OD1 no hydrogen 2.926 N/A TRP 24.A N ASN 21.A O no hydrogen 3.128 N/A GLY 25.A N TRP 322.A O no hydrogen 2.999 N/A PHE 26.A N GLU 288.A OE1 no hydrogen 2.705 N/A LYS 30.A N PRO 27.A O no hydrogen 2.714 N/A ARG 31.A N PRO 28.A O no hydrogen 3.316 N/A ARG 31.A NE PHE 26.A O no hydrogen 2.777 N/A ARG 31.A NH1 GLU 237.A OE1 no hydrogen 3.553 N/A ARG 31.A NH1 GLU 237.A OE2 no hydrogen 2.882 N/A ARG 31.A NH2 PHE 26.A O no hydrogen 3.113 N/A ARG 31.A NH2 GLU 237.A OE1 no hydrogen 2.658 N/A ARG 31.A NH2 GLU 237.A OE2 no hydrogen 3.491 N/A HIS 36.A N PRO 32.A O no hydrogen 2.784 N/A ILE 37.A N ILE 33.A O no hydrogen 3.013 N/A GLN 38.A N GLU 34.A O no hydrogen 3.282 N/A GLN 38.A NE2 GLU 87.A OE2 no hydrogen 3.300 N/A PHE 39.A N MET 35.A O no hydrogen 3.175 N/A GLY 40.A N ILE 37.A O no hydrogen 3.156 N/A VAL 41.A N GLN 234.A O no hydrogen 2.764 N/A ILE 42.A N VAL 84.A O no hydrogen 2.773 N/A LEU 44.A N LEU 82.A O no hydrogen 3.156 N/A ASP 45.A N ILE 208.A O no hydrogen 2.804 N/A LYS 46.A N GLY 80.A O no hydrogen 2.846 N/A LYS 46.A NZ PRO 47.A O no hydrogen 2.863 N/A LYS 46.A NZ PRO 50.A O no hydrogen 2.867 N/A LYS 46.A NZ ASP 75.A O no hydrogen 3.256 N/A LYS 46.A NZ PRO 76.A O no hydrogen 3.075 N/A LYS 46.A NZ VAL 78.A O no hydrogen 2.786 N/A GLY 49.A N PRO 76.A O no hydrogen 2.697 N/A THR 51.A N GLU 54.A OE1 no hydrogen 3.238 N/A THR 51.A OG1 GLU 54.A OE1 no hydrogen 3.466 N/A SER 52.A OG LEU 74.A O no hydrogen 2.688 N/A HIS 53.A ND1 HIS 70.A NE2 no hydrogen 2.992 N/A GLU 54.A N THR 51.A OG1 no hydrogen 3.151 N/A VAL 55.A N THR 51.A O no hydrogen 3.208 N/A VAL 56.A N SER 52.A O no hydrogen 3.201 N/A ALA 57.A N HIS 53.A O no hydrogen 3.122 N/A TRP 58.A N GLU 54.A O no hydrogen 2.831 N/A ILE 59.A N VAL 55.A O no hydrogen 2.933 N/A LYS 60.A N VAL 56.A O no hydrogen 2.912 N/A LYS 61.A N ALA 57.A O no hydrogen 3.063 N/A ILE 62.A N TRP 58.A O no hydrogen 2.911 N/A LEU 63.A N ILE 59.A O no hydrogen 2.969 N/A LEU 65.A N LYS 60.A O no hydrogen 2.904 N/A LYS 67.A N GLU 87.A OE1 no hydrogen 2.989 N/A GLY 69.A N ALA 85.A O no hydrogen 2.965 N/A HIS 70.A NE2 HIS 53.A ND1 no hydrogen 2.992 N/A GLY 71.A N PRO 83.A O no hydrogen 2.838 N/A GLY 72.A N HIS 70.A ND1 no hydrogen 3.264 N/A LEU 74.A N SER 52.A OG no hydrogen 2.849 N/A VAL 78.A N ASP 75.A O no hydrogen 2.913 N/A SER 79.A N LEU 193.A O no hydrogen 3.408 N/A GLY 80.A N LYS 46.A O no hydrogen 3.134 N/A VAL 81.A N ARG 195.A O no hydrogen 2.898 N/A LEU 82.A N LEU 44.A O no hydrogen 2.764 N/A VAL 84.A N ILE 42.A O no hydrogen 2.839 N/A ALA 85.A N GLY 69.A O no hydrogen 2.752 N/A LEU 86.A N GLY 40.A O no hydrogen 2.841 N/A GLU 87.A N LYS 67.A O no hydrogen 2.845 N/A LYS 88.A N GLN 38.A O no hydrogen 2.891 N/A ALA 89.A N LEU 86.A O no hydrogen 2.792 N/A THR 90.A N GLU 87.A O no hydrogen 3.209 N/A THR 90.A OG1 GLU 87.A O no hydrogen 2.703 N/A ARG 91.A NH2 VAL 316.A O no hydrogen 2.751 N/A VAL 92.A N ALA 89.A O no hydrogen 2.973 N/A VAL 93.A N THR 90.A O no hydrogen 3.386 N/A GLN 94.A N ARG 91.A O no hydrogen 3.242 N/A GLN 94.A NE2 ARG 91.A O no hydrogen 2.904 N/A ALA 95.A N VAL 92.A O no hydrogen 3.026 N/A LEU 96.A N VAL 93.A O no hydrogen 2.886 N/A LEU 97.A N VAL 93.A O no hydrogen 2.736 N/A ALA 99.A N LEU 96.A O no hydrogen 3.108 N/A LYS 101.A N VAL 167.A O no hydrogen 2.886 N/A LYS 101.A NZ LEU 96.A O no hydrogen 3.480 N/A LYS 101.A NZ LEU 97.A O no hydrogen 3.098 N/A LYS 101.A NZ ALA 99.A O no hydrogen 2.738 N/A GLU 102.A N ARG 197.A O no hydrogen 2.893 N/A TYR 103.A N VAL 165.A O no hydrogen 2.800 N/A VAL 104.A N ARG 194.A O no hydrogen 2.768 N/A ALA 105.A N PHE 163.A O no hydrogen 2.803 N/A LEU 106.A N GLU 192.A O no hydrogen 2.855 N/A MET 107.A N VAL 161.A O no hydrogen 2.834 N/A HIS 108.A N HIS 189.A O no hydrogen 2.814 N/A HIS 108.A ND1 ASP 160.A OD2 no hydrogen 3.163 N/A LEU 109.A N ARG 159.A O no hydrogen 2.837 N/A HIS 110.A N GLY 187.A O no hydrogen 2.873 N/A HIS 110.A NE2 HIS 189.A ND1 no hydrogen 2.866 N/A LYS 117.A N PRO 114.A O no hydrogen 3.142 N/A ILE 118.A N PRO 114.A O no hydrogen 3.201 N/A ILE 119.A N GLU 115.A O no hydrogen 3.178 N/A GLN 120.A N ASP 116.A O no hydrogen 3.015 N/A VAL 121.A N LYS 117.A O no hydrogen 3.016 N/A MET 122.A N ILE 118.A O no hydrogen 3.105 N/A LYS 123.A N ILE 119.A O no hydrogen 3.249 N/A GLU 124.A N VAL 121.A O no hydrogen 3.044 N/A PHE 125.A N MET 122.A O no hydrogen 3.305 N/A GLU 126.A N LYS 123.A O no hydrogen 3.500 N/A GLY 127.A N VAL 148.A O no hydrogen 2.767 N/A ILE 129.A N ARG 146.A O no hydrogen 2.752 N/A GLN 131.A N ARG 144.A O no hydrogen 2.831 N/A SER 137.A OG PRO 134.A O no hydrogen 2.862 N/A SER 137.A OG VAL 139.A O no hydrogen 3.468 N/A ARG 141.A NH1 PRO 133.A O no hydrogen 2.772 N/A ARG 142.A N LYS 140.A O no hydrogen 2.976 N/A ARG 144.A N GLN 131.A O no hydrogen 2.769 N/A ARG 144.A NH2 GLY 170.A O no hydrogen 2.743 N/A ARG 146.A N ILE 129.A O no hydrogen 2.834 N/A ARG 146.A NE ALA 169.A O no hydrogen 2.750 N/A ARG 146.A NH1 THR 145.A O no hydrogen 2.939 N/A LYS 147.A N GLU 168.A OE1 no hydrogen 3.007 N/A VAL 148.A N GLY 127.A O no hydrogen 2.796 N/A TYR 149.A N GLY 166.A O no hydrogen 2.813 N/A TYR 150.A OH GLU 102.A OE2 no hydrogen 2.442 N/A ILE 151.A N GLU 126.A OE1 no hydrogen 2.797 N/A GLU 152.A N ARG 164.A O no hydrogen 2.853 N/A LEU 154.A N LEU 162.A O no hydrogen 2.775 N/A GLU 155.A N LEU 162.A O no hydrogen 3.329 N/A GLU 157.A N ASP 160.A O no hydrogen 2.849 N/A ARG 159.A NE ASP 112.A OD1 no hydrogen 3.066 N/A ASP 160.A N GLU 157.A O no hydrogen 3.067 N/A VAL 161.A N MET 107.A O no hydrogen 2.788 N/A LEU 162.A N GLU 155.A O no hydrogen 2.895 N/A PHE 163.A N ALA 105.A O no hydrogen 2.967 N/A ARG 164.A N GLU 152.A O no hydrogen 2.758 N/A ARG 164.A NH1 GLU 102.A OE1 no hydrogen 2.714 N/A VAL 165.A N TYR 103.A O no hydrogen 2.815 N/A GLY 166.A N TYR 150.A O no hydrogen 3.005 N/A VAL 167.A N LYS 101.A O no hydrogen 2.797 N/A GLU 168.A N LYS 147.A O no hydrogen 2.900 N/A THR 171.A OG1 GLU 168.A O no hydrogen 2.652 N/A LEU 176.A N TYR 172.A O no hydrogen 2.993 N/A ILE 177.A N ILE 173.A O no hydrogen 2.824 N/A HIS 178.A N ARG 174.A O no hydrogen 3.042 N/A HIS 179.A N SER 175.A O no hydrogen 3.080 N/A HIS 179.A ND1 SER 175.A O no hydrogen 2.867 N/A ILE 180.A N LEU 176.A O no hydrogen 3.035 N/A GLY 181.A N ILE 177.A O no hydrogen 3.045 N/A LEU 182.A N HIS 178.A O no hydrogen 3.141 N/A ALA 183.A N HIS 179.A O no hydrogen 2.937 N/A LEU 184.A N ILE 180.A O no hydrogen 2.942 N/A GLY 185.A N LEU 182.A O no hydrogen 3.116 N/A GLY 187.A N GLY 181.A O no hydrogen 2.898 N/A HIS 189.A N HIS 108.A O no hydrogen 2.998 N/A HIS 189.A ND1 HIS 110.A NE2 no hydrogen 2.866 N/A SER 191.A N LEU 106.A O no hydrogen 2.920 N/A SER 191.A OG LEU 106.A O no hydrogen 3.163 N/A ARG 194.A N VAL 104.A O no hydrogen 2.946 N/A ARG 194.A NE GLU 203.A OE2 no hydrogen 3.319 N/A ARG 194.A NH1 ASP 45.A OD1 no hydrogen 2.866 N/A ARG 194.A NH1 SER 79.A OG no hydrogen 2.939 N/A ARG 194.A NH2 ASP 45.A OD1 no hydrogen 3.215 N/A ARG 194.A NH2 ASP 45.A OD2 no hydrogen 2.874 N/A ARG 194.A NH2 GLU 203.A OE2 no hydrogen 2.774 N/A ARG 195.A N SER 79.A O no hydrogen 2.938 N/A ARG 195.A NE VAL 81.A O no hydrogen 2.772 N/A ARG 195.A NH1 TYR 103.A OH no hydrogen 3.191 N/A ARG 195.A NH2 GLY 72.A O no hydrogen 2.886 N/A ARG 195.A NH2 VAL 81.A O no hydrogen 3.091 N/A THR 196.A N GLU 102.A O no hydrogen 2.876 N/A THR 196.A OG1 GLU 102.A O no hydrogen 3.359 N/A THR 196.A OG1 GLU 102.A OE1 no hydrogen 2.572 N/A ARG 197.A N GLU 102.A O no hydrogen 3.283 N/A SER 198.A N PHE 201.A O no hydrogen 2.899 N/A GLY 199.A N GLY 100.A O no hydrogen 2.969 N/A PHE 201.A N SER 198.A O no hydrogen 3.131 N/A ASP 204.A N LYS 202.A O no hydrogen 3.011 N/A THR 206.A N ASP 204.A OD1 no hydrogen 2.964 N/A THR 206.A OG1 ASN 43.A OD1 no hydrogen 3.243 N/A THR 206.A OG1 ASP 204.A OD1 no hydrogen 2.499 N/A LEU 207.A N ASP 204.A O no hydrogen 3.219 N/A ILE 208.A N ASN 43.A O no hydrogen 2.937 N/A ASP 212.A N THR 209.A OG1 no hydrogen 3.342 N/A LEU 213.A N THR 209.A O no hydrogen 2.945 N/A VAL 214.A N LEU 210.A O no hydrogen 2.924 N/A ASP 215.A N HIS 211.A O no hydrogen 3.028 N/A TYR 216.A N ASP 212.A O no hydrogen 2.824 N/A TYR 217.A N LEU 213.A O no hydrogen 3.026 N/A TYR 218.A N VAL 214.A O no hydrogen 3.040 N/A PHE 219.A N ASP 215.A O no hydrogen 2.882 N/A TRP 220.A N TYR 216.A O no hydrogen 3.095 N/A LYS 221.A N TYR 217.A O no hydrogen 2.775 N/A GLU 222.A N TYR 218.A O no hydrogen 2.793 N/A ASP 223.A N TYR 218.A O no hydrogen 3.261 N/A GLY 224.A N TRP 220.A O no hydrogen 2.977 N/A ILE 225.A N PHE 219.A O no hydrogen 2.854 N/A ARG 230.A N GLU 226.A O no hydrogen 3.008 N/A ARG 230.A NH1 ARG 31.A O no hydrogen 3.053 N/A ARG 230.A NH2 ARG 31.A O no hydrogen 2.694 N/A LYS 231.A N GLU 227.A O no hydrogen 3.302 N/A ALA 232.A N TYR 228.A O no hydrogen 3.187 N/A ALA 232.A N PHE 229.A O no hydrogen 3.183 N/A ILE 233.A N ARG 230.A O no hydrogen 3.313 N/A GLN 234.A N VAL 41.A O no hydrogen 2.758 N/A GLN 234.A NE2 LYS 231.A O no hydrogen 3.019 N/A MET 236.A N PHE 39.A O no hydrogen 2.955 N/A GLU 237.A N GLU 237.A OE2 no hydrogen 2.782 N/A LYS 238.A N PRO 235.A O no hydrogen 2.908 N/A LYS 238.A NZ PRO 200.A O no hydrogen 3.252 N/A LYS 238.A NZ GLU 241.A OE1 no hydrogen 2.800 N/A ALA 239.A N MET 236.A O no hydrogen 3.097 N/A VAL 240.A N GLU 237.A O no hydrogen 3.147 N/A GLU 241.A N LYS 238.A O no hydrogen 3.286 N/A HIS 242.A N HIS 242.A ND1 no hydrogen 2.947 N/A HIS 242.A NE2 ALA 95.A O no hydrogen 2.738 N/A LEU 243.A N VAL 240.A O no hydrogen 3.077 N/A LYS 245.A N HIS 271.A ND1 no hydrogen 3.065 N/A VAL 246.A N ALA 281.A O no hydrogen 3.017 N/A TRP 247.A N LYS 269.A O no hydrogen 2.655 N/A TRP 247.A NE1 ASP 287.A OD1 no hydrogen 2.919 N/A ILE 248.A N MET 283.A O no hydrogen 2.837 N/A LYS 249.A N GLY 266.A O no hydrogen 2.925 N/A LYS 249.A NZ ASP 15.A OD2 no hydrogen 3.510 N/A LYS 249.A NZ PRO 265.A O no hydrogen 2.846 N/A ALA 252.A N LYS 249.A O no hydrogen 3.004 N/A VAL 253.A N ASP 250.A O no hydrogen 3.236 N/A VAL 256.A N ALA 252.A O no hydrogen 3.165 N/A THR 257.A N VAL 253.A O no hydrogen 3.032 N/A THR 257.A OG1 VAL 253.A O no hydrogen 3.543 N/A THR 257.A OG1 ALA 254.A O no hydrogen 2.765 N/A HIS 258.A N ALA 254.A O no hydrogen 2.928 N/A HIS 258.A N ALA 255.A O no hydrogen 3.118 N/A GLY 259.A N VAL 256.A O no hydrogen 3.158 N/A ALA 260.A N ALA 255.A O no hydrogen 2.946 N/A LEU 262.A N VAL 311.A O no hydrogen 3.018 N/A VAL 264.A N GLY 308.A O no hydrogen 2.834 N/A GLY 266.A N ALA 263.A O no hydrogen 3.100 N/A ILE 267.A N VAL 264.A O no hydrogen 3.096 N/A ALA 268.A N TRP 247.A O no hydrogen 2.791 N/A LYS 269.A N TRP 247.A O no hydrogen 3.103 N/A LEU 270.A N LEU 12.A O no hydrogen 2.971 N/A HIS 271.A N LYS 245.A O no hydrogen 2.959 N/A ALA 272.A N GLU 10.A O no hydrogen 2.810 N/A ILE 274.A N SER 299.A OG no hydrogen 2.879 N/A LYS 275.A N ASP 278.A OD2 no hydrogen 3.028 N/A LYS 275.A NZ ASP 278.A OD2 no hydrogen 3.064 N/A ARG 276.A NE GLU 301.A OE2 no hydrogen 3.286 N/A ARG 276.A NH2 GLU 301.A OE1 no hydrogen 2.976 N/A ARG 276.A NH2 GLU 301.A OE2 no hydrogen 3.315 N/A GLY 277.A N ALA 295.A O no hydrogen 2.839 N/A ASP 278.A N LYS 275.A O no hydrogen 3.207 N/A VAL 280.A N GLY 293.A O no hydrogen 2.887 N/A ALA 281.A N PRO 244.A O no hydrogen 2.988 N/A ILE 282.A N ALA 291.A O no hydrogen 2.762 N/A MET 283.A N VAL 246.A O no hydrogen 2.874 N/A THR 284.A N GLU 288.A O no hydrogen 3.024 N/A THR 284.A OG1 GLU 288.A OE2 no hydrogen 2.697 N/A LYS 286.A N THR 284.A OG1 no hydrogen 3.156 N/A LYS 286.A NZ THR 20.A OG1 no hydrogen 2.584 N/A LYS 286.A NZ ASN 21.A O no hydrogen 2.723 N/A LYS 286.A NZ TRP 24.A O no hydrogen 3.097 N/A LYS 286.A NZ TYR 323.A OH no hydrogen 2.960 N/A ASP 287.A N THR 284.A O no hydrogen 2.981 N/A GLU 288.A N THR 284.A OG1 no hydrogen 3.068 N/A LEU 289.A N GLU 237.A OE1 no hydrogen 2.882 N/A VAL 290.A N ILE 282.A O no hydrogen 2.830 N/A ALA 291.A N ILE 282.A O no hydrogen 3.345 N/A LEU 292.A N LYS 315.A O no hydrogen 2.759 N/A GLY 293.A N VAL 280.A O no hydrogen 2.992 N/A LYS 294.A N ASP 312.A O no hydrogen 2.940 N/A ALA 295.A N ASP 278.A O no hydrogen 2.992 N/A MET 296.A N ALA 310.A O no hydrogen 2.774 N/A THR 298.A N GLU 301.A OE2 no hydrogen 3.129 N/A SER 299.A N ILE 274.A O no hydrogen 2.904 N/A SER 299.A OG HIS 271.A O no hydrogen 2.636 N/A GLU 301.A N THR 298.A OG1 no hydrogen 3.315 N/A MET 302.A N THR 298.A O no hydrogen 2.972 N/A LEU 303.A N SER 299.A O no hydrogen 3.165 N/A GLU 304.A N GLN 300.A O no hydrogen 2.986 N/A LYS 305.A N GLU 301.A O no hydrogen 3.117 N/A ALA 310.A N LEU 262.A O no hydrogen 2.803 N/A VAL 311.A N LEU 262.A O no hydrogen 3.137 N/A ASP 312.A N LYS 294.A O no hydrogen 2.805 N/A VAL 313.A N ASP 261.A OD1 no hydrogen 3.171 N/A GLU 314.A N LEU 292.A O no hydrogen 2.931 N/A LYS 315.A N LEU 292.A O no hydrogen 3.071 N/A PHE 317.A N VAL 290.A O no hydrogen 2.901 N/A MET 318.A N VAL 290.A O no hydrogen 3.189 N/A TYR 323.A OH GLU 288.A OE2 no hydrogen 2.600 N/A