Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3hd8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N PHE 167.A O no hydrogen 3.134 N/A LEU 6.A N ASN 94.A O no hydrogen 2.860 N/A ALA 7.A N ALA 165.A O no hydrogen 2.869 N/A VAL 9.A N GLY 163.A O no hydrogen 3.151 N/A THR 10.A N THR 19.A O no hydrogen 2.841 N/A LYS 11.A NZ GLU 340.A OE2 no hydrogen 2.456 N/A ASP 12.A N LEU 17.A O no hydrogen 2.917 N/A THR 15.A N ASP 12.A OD1 no hydrogen 3.220 N/A THR 15.A OG1 ASP 12.A OD1 no hydrogen 2.779 N/A SER 16.A N ASP 12.A O no hydrogen 2.710 N/A LEU 17.A N THR 15.A OG1 no hydrogen 3.265 N/A TYR 18.A OH GLU 340.A OE2 no hydrogen 2.793 N/A THR 19.A N THR 10.A O no hydrogen 2.811 N/A ILE 20.A N LEU 28.A O no hydrogen 2.996 N/A PHE 22.A N ALA 26.A O no hydrogen 2.871 N/A HIS 23.A ND1 ARG 90.A O no hydrogen 2.836 N/A ALA 26.A N HIS 23.A O no hydrogen 2.925 N/A SER 27.A N GLY 125.A O no hydrogen 3.150 N/A SER 27.A OG SER 126.A OG no hydrogen 3.303 N/A LEU 28.A N ILE 20.A O no hydrogen 2.978 N/A VAL 29.A N GLY 128.A O no hydrogen 2.910 N/A LEU 30.A N TYR 18.A O no hydrogen 2.804 N/A ASP 31.A N ALA 130.A O no hydrogen 3.002 N/A VAL 32.A N THR 225.A OG1 no hydrogen 3.048 N/A GLY 34.A N ASP 31.A O no hydrogen 2.862 N/A TRP 38.A N VAL 129.A O no hydrogen 2.879 N/A TRP 38.A NE1 SER 74.A O no hydrogen 2.837 N/A SER 39.A N ALA 112.A O no hydrogen 3.079 N/A SER 39.A OG THR 40.A O no hydrogen 2.827 N/A THR 40.A N THR 127.A O no hydrogen 2.988 N/A CYS 41.A SG SER 39.A O no hydrogen 3.748 N/A CYS 48.A N LYS 67.A O no hydrogen 3.122 N/A CYS 48.A SG LYS 67.A O no hydrogen 3.959 N/A SER 50.A N ALA 47.A O no hydrogen 2.844 N/A SER 50.A OG ALA 47.A O no hydrogen 2.692 N/A CYS 53.A N SER 50.A OG no hydrogen 3.062 N/A LEU 54.A N SER 50.A O no hydrogen 2.943 N/A LEU 55.A N PRO 51.A O no hydrogen 2.818 N/A ALA 56.A N THR 52.A O no hydrogen 3.017 N/A ASN 57.A N CYS 53.A O no hydrogen 3.178 N/A ASN 57.A N LEU 54.A O no hydrogen 3.168 N/A ALA 58.A N LEU 55.A O no hydrogen 3.307 N/A CYS 64.A N ALA 61.A O no hydrogen 2.926 N/A CYS 69.A N ILE 46.A O no hydrogen 3.022 N/A ALA 71.A N GLY 84.A O no hydrogen 2.757 N/A ASN 75.A N ALA 80.A O no hydrogen 2.935 N/A ASN 75.A ND2 LEU 118.A O no hydrogen 2.656 N/A ASN 75.A ND2 ALA 120.A O no hydrogen 2.788 N/A THR 78.A N ASN 75.A OD1 no hydrogen 2.973 N/A GLY 79.A N ASN 75.A O no hydrogen 2.935 N/A ALA 80.A N THR 78.A OG1 no hydrogen 3.140 N/A ALA 82.A N PRO 73.A O no hydrogen 3.125 N/A GLY 84.A N ALA 71.A O no hydrogen 2.886 N/A PHE 87.A N ALA 111.A O no hydrogen 2.834 N/A THR 89.A N VAL 109.A O no hydrogen 2.844 N/A ARG 90.A N THR 89.A OG1 no hydrogen 2.788 N/A PHE 91.A N VAL 107.A O no hydrogen 2.985 N/A ALA 92.A N PHE 22.A O no hydrogen 2.792 N/A ALA 93.A N VAL 105.A O no hydrogen 3.129 N/A ASN 94.A N LEU 6.A O no hydrogen 3.374 N/A THR 95.A N SER 103.A O no hydrogen 2.753 N/A THR 96.A N PRO 4.A O no hydrogen 2.967 N/A THR 96.A OG1 LYS 100.A O no hydrogen 2.701 N/A GLY 98.A N THR 96.A OG1 no hydrogen 3.340 N/A ASN 99.A N ASP 97.A OD2 no hydrogen 3.027 N/A LYS 100.A N ASP 97.A OD2 no hydrogen 3.059 N/A LYS 100.A NZ ASP 97.A OD1 no hydrogen 2.444 N/A VAL 102.A N THR 95.A O no hydrogen 2.879 N/A SER 103.A N THR 95.A OG1 no hydrogen 3.314 N/A VAL 105.A N ALA 93.A O no hydrogen 3.073 N/A VAL 107.A N PHE 91.A O no hydrogen 2.980 N/A VAL 109.A N THR 89.A O no hydrogen 2.894 N/A LEU 110.A N GLN 142.A OE1 no hydrogen 2.870 N/A ALA 111.A N PHE 87.A O no hydrogen 3.186 N/A ALA 112.A N VAL 37.A O no hydrogen 3.148 N/A CYS 113.A N SER 85.A O no hydrogen 2.960 N/A ALA 114.A N SER 39.A O no hydrogen 2.983 N/A LEU 118.A N PRO 115.A O no hydrogen 3.001 N/A LEU 119.A N SER 116.A O no hydrogen 3.206 N/A LEU 122.A N LEU 119.A O no hydrogen 3.065 N/A SER 126.A N PRO 123.A O no hydrogen 2.946 N/A SER 126.A OG SER 27.A OG no hydrogen 3.303 N/A THR 127.A N SER 27.A O no hydrogen 2.957 N/A VAL 129.A N TRP 38.A O no hydrogen 2.761 N/A ALA 130.A N VAL 29.A O no hydrogen 2.768 N/A GLY 131.A N LEU 36.A O no hydrogen 2.903 N/A LEU 132.A N ASP 31.A O no hydrogen 3.078 N/A ALA 133.A N GLY 34.A O no hydrogen 2.942 N/A SER 135.A OG LEU 35.A O no hydrogen 3.202 N/A SER 135.A OG ALA 133.A O no hydrogen 3.013 N/A ALA 138.A N SER 135.A OG no hydrogen 3.129 N/A LEU 139.A N GLY 131.A O no hydrogen 2.762 N/A SER 141.A OG GLY 136.A O no hydrogen 2.771 N/A SER 141.A OG ALA 138.A O no hydrogen 2.905 N/A GLN 142.A N ALA 138.A O no hydrogen 3.122 N/A GLN 142.A NE2 LEU 110.A O no hydrogen 2.711 N/A GLN 142.A NE2 LEU 137.A O no hydrogen 2.927 N/A VAL 143.A N LEU 139.A O no hydrogen 2.895 N/A ALA 144.A N PRO 140.A O no hydrogen 2.949 N/A SER 145.A N SER 141.A O no hydrogen 3.187 N/A ALA 146.A N GLN 142.A O no hydrogen 2.867 N/A GLN 147.A N VAL 143.A O no hydrogen 2.878 N/A VAL 149.A N ALA 144.A O no hydrogen 2.920 N/A ASN 151.A N GLU 349.A OE2 no hydrogen 3.290 N/A PHE 153.A N PHE 346.A O no hydrogen 3.027 N/A LEU 154.A N ILE 166.A O no hydrogen 2.665 N/A LEU 155.A N LEU 344.A O no hydrogen 3.022 N/A CYS 156.A N VAL 164.A O no hydrogen 2.876 N/A CYS 156.A SG PHE 342.A O no hydrogen 3.593 N/A GLY 163.A N VAL 9.A O no hydrogen 2.966 N/A VAL 164.A N CYS 156.A O no hydrogen 3.078 N/A ALA 165.A N ALA 7.A O no hydrogen 2.962 N/A ILE 166.A N LEU 154.A O no hydrogen 2.803 N/A PHE 167.A N VAL 5.A O no hydrogen 2.777 N/A GLY 168.A N LYS 152.A O no hydrogen 2.825 N/A TRP 174.A NE1 SER 366.A OG no hydrogen 2.981 N/A GLN 176.A N GLN 176.A OE1 no hydrogen 2.687 N/A PHE 177.A N TRP 174.A O no hydrogen 2.700 N/A THR 178.A N TRP 174.A O no hydrogen 2.857 N/A THR 178.A OG1 PRO 173.A O no hydrogen 2.977 N/A THR 178.A OG1 TRP 174.A O no hydrogen 3.243 N/A GLN 179.A NE2 PRO 175.A O no hydrogen 3.616 N/A SER 180.A N PHE 177.A O no hydrogen 3.355 N/A SER 180.A OG PHE 177.A O no hydrogen 2.895 N/A MET 181.A N THR 178.A O no hydrogen 3.174 N/A ASP 182.A N PHE 355.A O no hydrogen 3.314 N/A TYR 183.A OH ASP 345.A OD2 no hydrogen 3.190 N/A THR 184.A N LEU 353.A O no hydrogen 3.094 N/A THR 184.A OG1 ASP 291.A O no hydrogen 2.534 N/A LEU 186.A N LYS 351.A O no hydrogen 2.933 N/A VAL 187.A N TYR 196.A O no hydrogen 2.759 N/A LYS 189.A NZ THR 218.A O no hydrogen 3.059 N/A ALA 194.A N SER 192.A OG no hydrogen 3.405 N/A ILE 197.A N VAL 221.A O no hydrogen 2.910 N/A ARG 200.A N GLU 289.A O no hydrogen 3.068 N/A LYS 203.A N LEU 287.A O no hydrogen 2.701 N/A LYS 203.A NZ GLU 289.A OE2 no hydrogen 2.733 N/A VAL 204.A N THR 207.A O no hydrogen 2.937 N/A GLU 205.A N ASN 285.A O no hydrogen 2.853 N/A THR 207.A N VAL 204.A O no hydrogen 3.117 N/A ARG 208.A NH2 ILE 211.A O no hydrogen 3.138 N/A VAL 209.A N ILE 202.A O no hydrogen 2.928 N/A GLY 219.A N SER 198.A OG no hydrogen 3.036 N/A VAL 221.A N ILE 197.A O no hydrogen 2.942 N/A MET 222.A N VAL 332.A O no hydrogen 2.797 N/A LEU 223.A N HIS 195.A O no hydrogen 3.031 N/A SER 224.A N LEU 334.A O no hydrogen 3.003 N/A THR 225.A OG1 LEU 30.A O no hydrogen 3.057 N/A ARG 226.A N SER 224.A OG no hydrogen 2.984 N/A ARG 226.A NE ASP 31.A OD1 no hydrogen 2.907 N/A ARG 226.A NH2 ASP 31.A OD1 no hydrogen 3.345 N/A ARG 226.A NH2 ASP 31.A OD2 no hydrogen 2.839 N/A VAL 230.A N ALA 315.A O no hydrogen 2.829 N/A LEU 231.A N ILE 333.A O no hydrogen 2.848 N/A LEU 232.A N VAL 317.A O no hydrogen 2.978 N/A ARG 233.A N ALA 331.A O no hydrogen 3.316 N/A ARG 233.A NE ASP 235.A OD1 no hydrogen 2.850 N/A ARG 233.A NE ASP 235.A OD2 no hydrogen 3.292 N/A ARG 233.A NH1 ALA 329.A O no hydrogen 2.972 N/A ARG 233.A NH2 ALA 215.A O no hydrogen 3.000 N/A ARG 233.A NH2 ASP 235.A OD2 no hydrogen 2.816 N/A ARG 234.A NE VAL 322.A O no hydrogen 3.403 N/A VAL 236.A N ARG 233.A O no hydrogen 3.098 N/A TYR 237.A N ARG 233.A O no hydrogen 2.917 N/A LEU 240.A N VAL 236.A O no hydrogen 3.128 N/A VAL 241.A N TYR 237.A O no hydrogen 2.855 N/A ASP 242.A N ARG 238.A O no hydrogen 2.803 N/A ALA 243.A N PRO 239.A O no hydrogen 3.092 N/A PHE 244.A N LEU 240.A O no hydrogen 2.923 N/A THR 245.A N VAL 241.A O no hydrogen 2.827 N/A THR 245.A OG1 VAL 241.A O no hydrogen 3.146 N/A THR 245.A OG1 ASP 242.A O no hydrogen 3.000 N/A LYS 246.A N ASP 242.A O no hydrogen 3.121 N/A LYS 246.A NZ ASP 242.A O no hydrogen 3.217 N/A ALA 247.A N ALA 243.A O no hydrogen 2.989 N/A LEU 248.A N PHE 244.A O no hydrogen 2.871 N/A ALA 249.A N THR 245.A O no hydrogen 2.965 N/A ALA 250.A N LYS 246.A O no hydrogen 3.237 N/A ALA 250.A N ALA 247.A O no hydrogen 3.189 N/A GLN 251.A N LEU 248.A O no hydrogen 3.304 N/A ARG 257.A N THR 273.A OG1 no hydrogen 2.955 N/A VAL 259.A N CYS 268.A O no hydrogen 2.903 N/A PHE 265.A N VAL 262.A O no hydrogen 2.932 N/A TYR 269.A N ALA 312.A O no hydrogen 2.897 N/A ASP 270.A N ARG 257.A O no hydrogen 3.217 N/A THR 271.A N GLY 310.A O no hydrogen 2.713 N/A LYS 272.A N ASP 270.A OD1 no hydrogen 3.254 N/A THR 273.A N ASP 270.A O no hydrogen 2.797 N/A THR 273.A OG1 ASP 270.A O no hydrogen 2.609 N/A LEU 274.A N THR 271.A O no hydrogen 3.316 N/A ASN 277.A N GLY 280.A O no hydrogen 3.032 N/A GLY 280.A N ASN 277.A O no hydrogen 2.915 N/A TYR 281.A OH ASP 306.A OD1 no hydrogen 2.285 N/A TYR 281.A OH ASP 306.A OD2 no hydrogen 3.337 N/A TRP 282.A N GLY 275.A O no hydrogen 2.966 N/A VAL 283.A N TYR 281.A O no hydrogen 2.882 N/A ASN 285.A N GLU 205.A OE2 no hydrogen 2.881 N/A VAL 286.A N MET 298.A O no hydrogen 3.053 N/A LEU 287.A N LYS 203.A O no hydrogen 2.803 N/A LEU 288.A N TRP 296.A O no hydrogen 2.991 N/A GLU 289.A N SER 201.A O no hydrogen 2.924 N/A ASP 291.A N SER 198.A O no hydrogen 2.981 N/A GLY 293.A N LEU 290.A O no hydrogen 3.233 N/A TRP 296.A N LEU 288.A O no hydrogen 2.863 N/A TRP 296.A NE1 GLN 338.A O no hydrogen 2.978 N/A MET 298.A N VAL 286.A O no hydrogen 2.794 N/A THR 299.A OG1 GLY 279.A O no hydrogen 2.496 N/A LYS 301.A N GLY 279.A O no hydrogen 3.091 N/A LYS 301.A NZ ASP 341.A OD2 no hydrogen 2.822 N/A ASN 302.A N THR 299.A O no hydrogen 3.058 N/A ASN 302.A ND2 THR 299.A O no hydrogen 3.554 N/A SER 303.A N THR 299.A O no hydrogen 2.854 N/A SER 303.A N GLY 300.A O no hydrogen 3.101 N/A SER 303.A OG THR 299.A O no hydrogen 3.062 N/A MET 304.A N GLY 300.A O no hydrogen 3.026 N/A VAL 305.A N CYS 313.A O no hydrogen 2.979 N/A VAL 307.A N THR 311.A O no hydrogen 3.376 N/A THR 311.A N LYS 308.A O no hydrogen 2.901 N/A ALA 312.A N TYR 269.A O no hydrogen 2.983 N/A CYS 313.A N VAL 305.A O no hydrogen 2.996 N/A VAL 314.A N LEU 267.A O no hydrogen 2.875 N/A ALA 315.A N SER 303.A O no hydrogen 2.720 N/A VAL 317.A N VAL 230.A O no hydrogen 2.951 N/A MET 319.A N LEU 232.A O no hydrogen 2.648 N/A SER 328.A OG ASP 326.A OD1 no hydrogen 3.018 N/A VAL 332.A N GLY 220.A O no hydrogen 3.169 N/A ILE 333.A N LEU 231.A O no hydrogen 2.753 N/A LEU 334.A N MET 222.A O no hydrogen 2.928 N/A GLY 335.A N GLN 338.A OE1 no hydrogen 2.709 N/A GLY 336.A N LEU 227.A O no hydrogen 3.097 N/A ALA 337.A N PRO 228.A O no hydrogen 3.255 N/A GLN 338.A N GLY 335.A O no hydrogen 3.157 N/A GLN 338.A NE2 PRO 228.A O no hydrogen 3.104 N/A GLN 338.A NE2 ASN 302.A O no hydrogen 2.757 N/A MET 339.A N GLY 336.A O no hydrogen 2.930 N/A GLU 340.A N GLY 336.A O no hydrogen 3.146 N/A ASP 341.A N LEU 157.A O no hydrogen 2.897 N/A PHE 342.A N MET 339.A O no hydrogen 3.061 N/A VAL 343.A N LEU 356.A O no hydrogen 2.912 N/A LEU 344.A N LEU 155.A O no hydrogen 2.762 N/A ASP 345.A N GLY 354.A O no hydrogen 2.687 N/A PHE 346.A N PHE 153.A O no hydrogen 2.746 N/A ASP 347.A N ARG 352.A O no hydrogen 2.805 N/A LYS 350.A N ASP 347.A OD1 no hydrogen 3.025 N/A LYS 351.A N MET 348.A O no hydrogen 3.306 N/A LYS 351.A NZ MET 348.A O no hydrogen 3.242 N/A ARG 352.A N ASP 347.A O no hydrogen 3.108 N/A LEU 353.A N THR 184.A O no hydrogen 2.826 N/A GLY 354.A N ASP 345.A O no hydrogen 2.782 N/A PHE 355.A N ASP 182.A O no hydrogen 3.082 N/A LEU 356.A N VAL 343.A O no hydrogen 3.019 N/A ARG 357.A NH1 ALA 297.A O no hydrogen 3.236 N/A LEU 358.A N ASP 341.A O no hydrogen 2.870 N/A THR 362.A N PRO 359.A O no hydrogen 3.188 N/A THR 362.A OG1 SER 366.A OG no hydrogen 3.093 N/A GLY 363.A N THR 362.A OG1 no hydrogen 2.837 N/A CYS 364.A N ASP 341.A OD1 no hydrogen 2.776 N/A CYS 364.A SG LEU 157.A O no hydrogen 3.018 N/A CYS 364.A SG ASP 341.A OD1 no hydrogen 3.856 N/A SER 366.A N GLY 363.A O no hydrogen 3.317 N/A SER 366.A OG THR 362.A OG1 no hydrogen 3.093 N/A SER 366.A OG GLY 363.A O no hydrogen 2.875 N/A ALA 370.A N ASN 368.A O no hydrogen 3.128 N/A