Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3hrd_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A NZ ASP 3.A O no hydrogen 2.800 N/A LYS 2.A NZ PRO 47.A O no hydrogen 2.775 N/A LYS 2.A NZ ASP 48.A OD1 no hydrogen 2.568 N/A GLU 5.A N ASP 48.A O no hydrogen 2.857 N/A PHE 7.A N VAL 50.A O no hydrogen 2.885 N/A LYS 10.A N GLU 14.A OE2 no hydrogen 3.011 N/A LEU 12.A N GLU 58.A OE2 no hydrogen 3.394 N/A GLU 14.A N THR 11.A OG1 no hydrogen 3.172 N/A ALA 15.A N THR 11.A O no hydrogen 3.098 N/A LYS 16.A N LEU 12.A O no hydrogen 2.899 N/A LYS 16.A NZ GLU 138.A OE1 no hydrogen 2.814 N/A GLY 17.A N GLU 13.A O no hydrogen 2.903 N/A LEU 18.A N GLU 14.A O no hydrogen 2.913 N/A LEU 19.A N ALA 15.A O no hydrogen 2.812 N/A HIS 20.A N LYS 16.A O no hydrogen 2.927 N/A GLN 21.A N GLY 17.A O no hydrogen 2.906 N/A TYR 22.A N LEU 18.A O no hydrogen 2.996 N/A LYS 23.A N HIS 20.A O no hydrogen 3.234 N/A VAL 25.A N TYR 22.A O no hydrogen 2.984 N/A ALA 28.A N VAL 49.A O no hydrogen 2.871 N/A ILE 30.A N ILE 51.A O no hydrogen 2.881 N/A VAL 37.A N GLY 33.A O no hydrogen 3.093 N/A GLU 39.A N ASP 35.A O no hydrogen 3.021 N/A ILE 40.A N LEU 36.A O no hydrogen 2.759 N/A ASN 41.A N VAL 37.A O no hydrogen 2.815 N/A ASP 42.A N ILE 38.A O no hydrogen 2.802 N/A ARG 43.A N ILE 40.A O no hydrogen 2.911 N/A TRP 44.A N GLU 39.A O no hydrogen 2.548 N/A GLU 45.A N GLU 39.A O no hydrogen 2.953 N/A VAL 50.A N GLU 5.A O no hydrogen 2.777 N/A ILE 51.A N ALA 28.A O no hydrogen 2.842 N/A ASP 52.A N PHE 7.A O no hydrogen 2.754 N/A ILE 53.A N ILE 30.A O no hydrogen 3.011 N/A LYS 54.A N ASP 52.A OD1 no hydrogen 2.967 N/A LYS 54.A NZ LEU 108.A O no hydrogen 2.980 N/A LEU 56.A N ILE 53.A O no hydrogen 3.013 N/A LYS 57.A N LYS 55.A O no hydrogen 2.871 N/A LEU 59.A N LEU 56.A O no hydrogen 2.778 N/A GLU 60.A N LYS 57.A O no hydrogen 2.905 N/A TYR 61.A N SER 75.A OG no hydrogen 3.428 N/A TYR 61.A OH GLU 171.A OE1 no hydrogen 2.536 N/A ARG 63.A N HIS 70.A O no hydrogen 2.969 N/A GLU 65.A N THR 68.A O no hydrogen 2.875 N/A THR 68.A OG1 HIS 70.A NE2 no hydrogen 2.478 N/A ILE 69.A N ILE 174.A O no hydrogen 2.707 N/A HIS 70.A N ARG 63.A O no hydrogen 3.003 N/A HIS 70.A ND1 GLU 171.A OE2 no hydrogen 2.695 N/A HIS 70.A NE2 THR 68.A OG1 no hydrogen 2.478 N/A ILE 71.A N VAL 172.A O no hydrogen 2.688 N/A GLY 72.A N TYR 61.A O no hydrogen 2.951 N/A ALA 73.A N THR 170.A O no hydrogen 2.874 N/A LEU 74.A N LEU 59.A O no hydrogen 3.182 N/A SER 75.A N GLY 72.A O no hydrogen 3.004 N/A SER 75.A OG TYR 61.A O no hydrogen 3.168 N/A SER 75.A OG GLY 72.A O no hydrogen 2.706 N/A THR 76.A N GLN 79.A OE1 no hydrogen 3.078 N/A PHE 77.A N GLY 109.A O no hydrogen 3.014 N/A THR 78.A N ARG 106.A O no hydrogen 3.141 N/A THR 78.A OG1 ASN 107.A OD1 no hydrogen 2.699 N/A GLN 79.A N THR 76.A OG1 no hydrogen 3.087 N/A GLN 79.A NE2 GLU 60.A OE1 no hydrogen 3.025 N/A ILE 80.A N THR 76.A O no hydrogen 3.002 N/A GLU 81.A N PHE 77.A O no hydrogen 2.848 N/A ASN 82.A N THR 78.A O no hydrogen 3.082 N/A HIS 83.A N ILE 80.A O no hydrogen 3.363 N/A PHE 85.A N HIS 83.A ND1 no hydrogen 3.146 N/A ARG 87.A N HIS 83.A O no hydrogen 2.773 N/A SER 88.A N PRO 84.A O no hydrogen 2.859 N/A SER 88.A OG PRO 84.A O no hydrogen 2.856 N/A HIS 89.A N PHE 85.A O no hydrogen 2.701 N/A VAL 90.A N ILE 86.A O no hydrogen 3.043 N/A ARG 91.A NE ARG 87.A O no hydrogen 3.267 N/A ARG 91.A NH2 ARG 87.A O no hydrogen 3.466 N/A ALA 92.A N SER 183.A OG no hydrogen 3.075 N/A LEU 93.A N VAL 90.A O no hydrogen 2.993 N/A TYR 94.A N VAL 90.A O no hydrogen 3.026 N/A LYS 95.A N ARG 91.A O no hydrogen 2.965 N/A ALA 96.A N ALA 92.A O no hydrogen 3.247 N/A ALA 97.A N LEU 93.A O no hydrogen 2.829 N/A SER 98.A N TYR 94.A O no hydrogen 2.948 N/A SER 98.A OG TYR 94.A O no hydrogen 2.998 N/A SER 98.A OG LYS 95.A O no hydrogen 3.057 N/A GLN 99.A N ALA 96.A O no hydrogen 3.122 N/A VAL 100.A N ALA 97.A O no hydrogen 3.407 N/A SER 102.A OG GLN 104.A OE1 no hydrogen 3.455 N/A GLN 104.A N GLN 104.A OE1 no hydrogen 2.839 N/A ARG 106.A N SER 102.A O no hydrogen 2.814 N/A ARG 106.A NE GLU 81.A OE1 no hydrogen 3.380 N/A ARG 106.A NH1 VAL 100.A O no hydrogen 2.902 N/A ASN 107.A N PRO 103.A O no hydrogen 2.764 N/A LEU 108.A N GLN 104.A O no hydrogen 3.309 N/A LEU 108.A N ILE 105.A O no hydrogen 3.300 N/A GLY 109.A N ILE 105.A O no hydrogen 2.624 N/A THR 110.A OG1 ALA 73.A O no hydrogen 3.495 N/A ILE 111.A N SER 75.A O no hydrogen 3.025 N/A GLY 112.A N ALA 73.A O no hydrogen 2.875 N/A GLY 113.A N THR 110.A OG1 no hydrogen 3.020 N/A ASN 114.A N THR 110.A O no hydrogen 3.032 N/A LEU 115.A N ILE 111.A O no hydrogen 3.003 N/A SER 116.A N GLY 112.A O no hydrogen 2.861 N/A SER 116.A OG GLY 112.A O no hydrogen 2.627 N/A THR 117.A N GLY 113.A O no hydrogen 2.797 N/A THR 117.A OG1 ASP 35.A OD2 no hydrogen 2.622 N/A THR 117.A OG1 GLY 113.A O no hydrogen 3.092 N/A SER 118.A N ASN 114.A O no hydrogen 3.018 N/A SER 118.A OG LEU 115.A O no hydrogen 2.645 N/A ALA 121.A N SER 119.A OG no hydrogen 3.062 N/A GLY 122.A N SER 119.A O no hydrogen 3.021 N/A VAL 125.A N ASN 114.A OD1 no hydrogen 2.956 N/A SER 126.A N GLY 122.A O no hydrogen 2.879 N/A SER 126.A OG GLY 200.A O no hydrogen 2.785 N/A ALA 127.A N ASP 123.A O no hydrogen 3.016 N/A MET 128.A N GLY 124.A O no hydrogen 2.842 N/A THR 129.A N VAL 125.A O no hydrogen 3.003 N/A THR 129.A OG1 VAL 125.A O no hydrogen 2.535 N/A THR 130.A N SER 126.A O no hydrogen 2.959 N/A THR 130.A OG1 SER 126.A O no hydrogen 2.839 N/A LEU 131.A N ALA 127.A O no hydrogen 2.893 N/A ASP 132.A N THR 129.A O no hydrogen 3.059 N/A ALA 133.A N MET 128.A O no hydrogen 2.855 N/A THR 134.A N ILE 173.A O no hydrogen 2.866 N/A VAL 135.A N MET 146.A O no hydrogen 2.934 N/A VAL 136.A N GLU 171.A O no hydrogen 2.935 N/A LEU 137.A N ARG 144.A O no hydrogen 2.865 N/A GLU 138.A N ILE 168.A O no hydrogen 3.039 N/A SER 139.A N GLY 142.A O no hydrogen 3.089 N/A ARG 141.A N SER 139.A OG no hydrogen 3.170 N/A ARG 141.A NE ASP 166.A OD2 no hydrogen 2.806 N/A ARG 141.A NH2 ASP 166.A OD1 no hydrogen 3.059 N/A ARG 141.A NH2 ASP 166.A OD2 no hydrogen 3.550 N/A GLY 142.A N SER 139.A O no hydrogen 3.104 N/A THR 143.A OG1 LEU 137.A O no hydrogen 3.379 N/A ARG 144.A N LEU 137.A O no hydrogen 2.905 N/A ARG 144.A NE GLU 167.A OE2 no hydrogen 2.880 N/A ARG 144.A NH2 ALA 162.A O no hydrogen 2.975 N/A ARG 144.A NH2 GLU 167.A OE1 no hydrogen 2.777 N/A ARG 144.A NH2 GLU 167.A OE2 no hydrogen 3.268 N/A MET 146.A N VAL 135.A O no hydrogen 3.041 N/A LYS 147.A NZ ASP 132.A O no hydrogen 2.830 N/A LYS 147.A NZ ASP 132.A OD1 no hydrogen 3.440 N/A LYS 147.A NZ ASP 132.A OD2 no hydrogen 3.452 N/A LEU 148.A N ALA 133.A O no hydrogen 2.811 N/A ASP 150.A N LYS 147.A O no hydrogen 2.779 N/A PHE 151.A N LYS 147.A O no hydrogen 2.850 N/A PHE 152.A N LEU 148.A O no hydrogen 2.894 N/A ASP 153.A N THR 149.A O no hydrogen 3.066 N/A GLY 154.A N ASP 150.A O no hydrogen 2.859 N/A GLY 156.A N ASN 161.A O no hydrogen 2.964 N/A PHE 157.A N LEU 163.A O no hydrogen 3.069 N/A ASN 161.A ND2 LEU 115.A O no hydrogen 3.668 N/A ASN 161.A ND2 SER 116.A O no hydrogen 2.964 N/A ASN 161.A ND2 SER 118.A OG no hydrogen 2.761 N/A ALA 162.A N PHE 151.A O no hydrogen 2.831 N/A LEU 163.A N ASN 161.A OD1 no hydrogen 3.066 N/A GLU 164.A N GLU 167.A OE1 no hydrogen 2.953 N/A GLU 167.A N GLU 164.A O no hydrogen 3.100 N/A ILE 168.A N GLU 138.A O no hydrogen 2.858 N/A THR 170.A N VAL 136.A O no hydrogen 2.960 N/A THR 170.A OG1 VAL 136.A O no hydrogen 3.470 N/A THR 170.A OG1 GLU 138.A OE2 no hydrogen 2.701 N/A VAL 172.A N ILE 71.A O no hydrogen 2.735 N/A ILE 173.A N THR 134.A O no hydrogen 2.758 N/A ILE 174.A N ILE 69.A O no hydrogen 2.973 N/A ARG 176.A N ASN 67.A O no hydrogen 2.588 N/A ARG 176.A NH1 GLU 65.A O no hydrogen 2.992 N/A HIS 180.A ND1 HIS 180.A O no hydrogen 3.017 N/A ALA 182.A N VAL 205.A O no hydrogen 3.079 N/A ALA 184.A N MET 203.A O no hydrogen 2.601 N/A TYR 186.A N GLY 201.A O no hydrogen 2.835 N/A LYS 187.A NZ GLN 99.A O no hydrogen 2.724 N/A LYS 187.A NZ ASP 123.A OD2 no hydrogen 2.901 N/A LYS 187.A NZ ALA 195.A O no hydrogen 2.901 N/A LEU 188.A N ILE 199.A O no hydrogen 3.006 N/A ARG 191.A NE LEU 194.A O no hydrogen 2.926 N/A ARG 191.A NH2 LEU 194.A O no hydrogen 2.827 N/A LEU 194.A N GLY 101.A O no hydrogen 2.901 N/A SER 197.A OG ASP 123.A OD1 no hydrogen 2.540 N/A VAL 198.A N LEU 188.A O no hydrogen 2.803 N/A ILE 199.A N LEU 188.A O no hydrogen 3.517 N/A GLY 200.A N GLY 221.A O no hydrogen 2.737 N/A GLY 201.A N TYR 186.A O no hydrogen 2.946 N/A GLY 202.A N ARG 219.A O no hydrogen 3.066 N/A MET 203.A N ALA 184.A O no hydrogen 2.884 N/A ALA 204.A N SER 217.A O no hydrogen 2.871 N/A VAL 205.A N ALA 182.A O no hydrogen 2.806 N/A LYS 206.A N TRP 215.A O no hydrogen 3.050 N/A ASP 208.A N VAL 212.A O no hydrogen 2.789 N/A GLY 211.A N ASP 208.A O no hydrogen 2.935 N/A CYS 213.A N ALA 240.A O no hydrogen 2.841 N/A CYS 213.A SG LYS 206.A O no hydrogen 3.723 N/A CYS 213.A SG TRP 215.A O no hydrogen 3.411 N/A THR 214.A N LYS 206.A O no hydrogen 2.794 N/A THR 214.A OG1 VAL 212.A O no hydrogen 3.516 N/A TRP 215.A N LYS 206.A O no hydrogen 3.480 N/A SER 217.A N ALA 204.A O no hydrogen 2.782 N/A SER 217.A OG THR 130.A O no hydrogen 2.669 N/A MET 218.A N GLU 234.A OE2 no hydrogen 2.720 N/A ARG 219.A N GLY 202.A O no hydrogen 2.834 N/A ARG 219.A NH1 PRO 227.A O no hydrogen 2.947 N/A GLY 220.A N LEU 228.A O no hydrogen 2.797 N/A GLY 221.A N GLY 200.A O no hydrogen 2.845 N/A CYS 222.A SG SER 197.A O no hydrogen 3.275 N/A CYS 222.A SG VAL 198.A O no hydrogen 3.541 N/A ILE 223.A N GLY 220.A O no hydrogen 3.031 N/A ARG 225.A NH1 SER 118.A O no hydrogen 2.814 N/A ARG 225.A NH1 ARG 225.A O no hydrogen 2.754 N/A ARG 225.A NH2 SER 118.A O no hydrogen 3.081 N/A TYR 226.A OH ARG 160.A O no hydrogen 2.394 N/A LEU 228.A N GLY 220.A O no hydrogen 3.004 N/A HIS 229.A NE2 GLU 234.A OE1 no hydrogen 2.814 N/A PHE 230.A N MET 218.A O no hydrogen 3.042 N/A LYS 231.A NZ GLU 235.A OE2 no hydrogen 2.729 N/A GLU 234.A N PHE 230.A O no hydrogen 3.030 N/A GLU 235.A N LYS 231.A O no hydrogen 2.971 N/A MET 236.A N GLN 232.A O no hydrogen 3.108 N/A MET 236.A N ALA 233.A O no hydrogen 3.132 N/A LEU 237.A N GLU 234.A O no hydrogen 2.812 N/A VAL 238.A N GLU 234.A O no hydrogen 3.093 N/A GLY 239.A N CYS 213.A O no hydrogen 2.879 N/A ALA 240.A N LEU 237.A O no hydrogen 3.306 N/A THR 246.A N THR 243.A O no hydrogen 2.870 N/A MET 247.A N THR 243.A O no hydrogen 2.864 N/A GLU 248.A N MET 244.A O no hydrogen 2.753 N/A ALA 249.A N GLU 245.A O no hydrogen 3.192 N/A THR 250.A N MET 247.A O no hydrogen 3.064 N/A THR 250.A OG1 MET 247.A O no hydrogen 2.678 N/A LEU 251.A N GLU 248.A O no hydrogen 2.759 N/A LEU 254.A N THR 250.A O no hydrogen 2.970 N/A HIS 255.A N LEU 251.A O no hydrogen 2.976 N/A HIS 255.A ND1 ASP 256.A OD1 no hydrogen 2.877 N/A ASP 256.A N PRO 252.A O no hydrogen 2.934 N/A THR 257.A N ILE 253.A O no hydrogen 2.925 N/A VAL 258.A N LEU 254.A O no hydrogen 2.978 N/A VAL 258.A N HIS 255.A O no hydrogen 3.054 N/A TYR 259.A N HIS 255.A O no hydrogen 3.122 N/A ASP 260.A N ASP 256.A O no hydrogen 2.998 N/A MET 261.A N THR 257.A O no hydrogen 2.884 N/A ALA 262.A N VAL 258.A O no hydrogen 2.698 N/A ARG 263.A NH1 ASP 260.A OD1 no hydrogen 3.162 N/A ARG 263.A NH2 ASP 260.A OD1 no hydrogen 3.205 N/A ARG 265.A N ALA 262.A O no hydrogen 2.772 N/A VAL 268.A N ARG 265.A O no hydrogen 3.462 N/A TYR 270.A N SER 267.A O no hydrogen 2.921 N/A LYS 271.A N SER 267.A O no hydrogen 2.912 N/A LYS 271.A NZ VAL 198.A O no hydrogen 2.697 N/A LYS 271.A NZ CYS 222.A O no hydrogen 3.130 N/A LYS 272.A N VAL 268.A O no hydrogen 2.934 N/A LYS 272.A NZ HIS 255.A NE2 no hydrogen 2.714 N/A LYS 272.A NZ GLU 273.A OE2 no hydrogen 2.648 N/A GLU 273.A N TYR 270.A O no hydrogen 2.982 N/A SER 274.A N TYR 270.A O no hydrogen 2.974 N/A SER 274.A OG TYR 270.A O no hydrogen 3.380 N/A VAL 275.A N LYS 271.A O no hydrogen 2.941 N/A GLN 276.A N GLU 273.A O no hydrogen 2.771 N/A VAL 278.A N SER 274.A O no hydrogen 2.854 N/A PHE 279.A N VAL 275.A O no hydrogen 3.121 N/A LYS 280.A N GLN 276.A O no hydrogen 3.234 N/A LYS 281.A N GLY 277.A O no hydrogen 3.433 N/A LEU 282.A N VAL 278.A O no hydrogen 3.118 N/A PHE 283.A N PHE 279.A O no hydrogen 2.653 N/A VAL 284.A N LYS 280.A O no hydrogen 3.032 N/A ASP 285.A N LYS 281.A O no hydrogen 3.039 N/A ILE 286.A N LEU 282.A O no hydrogen 2.894 N/A LEU 287.A N PHE 283.A O no hydrogen 2.967 N/A ASP 288.A N VAL 284.A O no hydrogen 2.952 N/A GLN 289.A N ASP 285.A O no hydrogen 3.149 N/A GLN 289.A NE2 SER 183.A O no hydrogen 2.769 N/A GLN 289.A NE2 ASP 285.A O no hydrogen 3.625 N/A GLN 289.A NE2 ASP 285.A OD2 no hydrogen 3.382 N/A LEU 290.A N ILE 286.A O no hydrogen 3.148 N/A GLU 291.A N LEU 287.A O no hydrogen 3.102 N/A