Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3hzi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A NZ GLU 105.A OE1 no hydrogen 3.495 N/A LEU 3.A N LEU 15.A O no hydrogen 3.041 N/A VAL 4.A N ILE 103.A O no hydrogen 2.806 N/A THR 5.A N GLY 13.A O no hydrogen 3.282 N/A TRP 6.A N THR 101.A O no hydrogen 2.962 N/A MET 7.A N GLN 10.A O no hydrogen 3.272 N/A ASN 8.A ND2 ARG 234.A O no hydrogen 2.542 N/A ARG 11.A NH1 GLU 14.A OE2 no hydrogen 3.328 N/A ARG 11.A NH2 GLU 14.A OE2 no hydrogen 2.700 N/A VAL 12.A N THR 5.A O no hydrogen 2.760 N/A GLY 13.A N THR 5.A O no hydrogen 3.332 N/A GLU 14.A N LYS 26.A O no hydrogen 3.259 N/A THR 16.A N THR 24.A O no hydrogen 2.643 N/A LEU 18.A N ALA 22.A O no hydrogen 3.038 N/A THR 24.A N THR 16.A O no hydrogen 2.661 N/A THR 24.A OG1 THR 16.A O no hydrogen 3.294 N/A PHE 25.A N ILE 51.A O no hydrogen 3.410 N/A TYR 27.A OH LEU 44.A O no hydrogen 2.399 N/A ALA 28.A N VAL 12.A O no hydrogen 3.084 N/A LEU 32.A N ALA 28.A O no hydrogen 3.010 N/A ALA 33.A N GLU 30.A O no hydrogen 3.051 N/A SER 34.A N TRP 31.A O no hydrogen 3.030 N/A SER 34.A OG GLN 10.A OE1 no hydrogen 3.134 N/A TYR 36.A N SER 34.A OG no hydrogen 3.060 N/A ALA 37.A N SER 34.A O no hydrogen 3.156 N/A ARG 38.A NE TYR 36.A O no hydrogen 2.811 N/A ARG 38.A NH1 ILE 303.A O no hydrogen 3.349 N/A ARG 38.A NH2 TYR 36.A O no hydrogen 3.347 N/A LEU 40.A N TYR 27.A OH no hydrogen 3.030 N/A SER 41.A OG SER 43.A OG no hydrogen 2.485 N/A SER 41.A OG GLU 238.A OE2 no hydrogen 2.694 N/A LEU 42.A N GLU 238.A OE1 no hydrogen 3.425 N/A SER 43.A N SER 41.A OG no hydrogen 3.081 N/A SER 43.A OG SER 41.A OG no hydrogen 2.485 N/A SER 43.A OG GLN 242.A O no hydrogen 3.092 N/A LEU 44.A N SER 41.A O no hydrogen 2.546 N/A ILE 51.A N PHE 25.A O no hydrogen 2.627 N/A VAL 56.A N SER 53.A O no hydrogen 2.893 N/A ASN 58.A N ASP 54.A O no hydrogen 2.812 N/A ASN 58.A ND2 GLY 245.A O no hydrogen 3.132 N/A PHE 59.A N ALA 55.A O no hydrogen 3.177 N/A PHE 60.A N VAL 56.A O no hydrogen 3.414 N/A ASP 61.A N PHE 57.A O no hydrogen 2.749 N/A ASN 62.A N ASN 58.A O no hydrogen 3.044 N/A ASN 62.A ND2 ASN 58.A O no hydrogen 3.240 N/A ASN 62.A ND2 LEU 246.A O no hydrogen 3.070 N/A LEU 63.A N PHE 60.A O no hydrogen 3.117 N/A LEU 64.A N ASP 61.A O no hydrogen 3.030 N/A ASP 66.A N GLY 149.A O no hydrogen 2.861 N/A ILE 69.A N SER 67.A OG no hydrogen 3.176 N/A VAL 70.A N SER 67.A O no hydrogen 2.942 N/A ARG 71.A N SER 67.A O no hydrogen 3.095 N/A ARG 71.A NE ARG 83.A O no hydrogen 3.622 N/A ARG 73.A N ILE 69.A O no hydrogen 3.010 N/A ILE 74.A N VAL 70.A O no hydrogen 2.914 N/A ILE 74.A N ARG 71.A O no hydrogen 2.955 N/A VAL 75.A N ARG 71.A O no hydrogen 3.181 N/A LYS 76.A NZ ASP 134.A O no hydrogen 2.778 N/A ARG 77.A NH2 PRO 136.A O no hydrogen 3.239 N/A TYR 78.A OH PHE 143.A O no hydrogen 2.422 N/A GLN 84.A N SER 82.A OG no hydrogen 2.448 N/A GLN 84.A NE2 HIS 23.A NE2 no hydrogen 2.686 N/A LEU 88.A N GLN 84.A O no hydrogen 3.348 N/A LEU 89.A N PRO 85.A O no hydrogen 2.897 N/A SER 90.A N PHE 86.A O no hydrogen 2.775 N/A SER 90.A N ASP 87.A O no hydrogen 2.773 N/A SER 90.A OG PHE 86.A O no hydrogen 2.654 N/A GLU 91.A N ASP 87.A O no hydrogen 2.999 N/A GLU 91.A N LEU 88.A O no hydrogen 2.654 N/A ILE 92.A N LEU 88.A O no hydrogen 2.775 N/A ASP 95.A N ARG 144.A O no hydrogen 3.142 N/A SER 96.A OG VAL 97.A O no hydrogen 3.139 N/A GLY 98.A N ASP 222.A OD2 no hydrogen 3.259 N/A THR 101.A N TRP 6.A O no hydrogen 3.011 N/A THR 101.A OG1 ALA 99.A O no hydrogen 3.473 N/A LEU 102.A N GLY 93.A O no hydrogen 3.235 N/A ILE 103.A N VAL 4.A O no hydrogen 3.134 N/A GLU 105.A N LYS 2.A O no hydrogen 3.283 N/A HIS 111.A N VAL 109.A O no hydrogen 2.412 N/A ALA 115.A N THR 170.A OG1 no hydrogen 3.013 N/A GLU 117.A N ILE 165.A O no hydrogen 3.216 N/A ARG 123.A N THR 120.A OG1 no hydrogen 2.867 N/A LEU 124.A N THR 120.A O no hydrogen 2.850 N/A GLU 126.A N ALA 122.A O no hydrogen 2.688 N/A VAL 127.A N ARG 123.A O no hydrogen 3.117 N/A LEU 128.A N LEU 124.A O no hydrogen 3.093 N/A THR 129.A N GLU 126.A O no hydrogen 2.957 N/A THR 129.A OG1 GLU 125.A O no hydrogen 2.882 N/A THR 129.A OG1 GLU 126.A O no hydrogen 2.755 N/A ALA 130.A N VAL 127.A O no hydrogen 3.315 N/A LYS 132.A N THR 129.A O no hydrogen 2.915 N/A LYS 132.A NZ ASN 212.A OD1 no hydrogen 3.110 N/A ILE 135.A N ALA 130.A O no hydrogen 3.129 N/A GLU 141.A N ILE 139.A O no hydrogen 2.655 N/A SER 146.A N ASP 95.A O no hydrogen 3.131 N/A GLY 149.A N ASP 66.A OD2 no hydrogen 3.147 N/A LYS 153.A NZ ALA 148.A O no hydrogen 2.639 N/A THR 154.A N ILE 176.A O no hydrogen 2.700 N/A THR 154.A OG1 LEU 137.A O no hydrogen 3.028 N/A LEU 156.A N HIS 174.A O no hydrogen 2.610 N/A ILE 159.A N ASP 162.A O no hydrogen 3.331 N/A CYS 164.A SG ASP 162.A O no hydrogen 3.527 N/A ILE 165.A N GLU 117.A O no hydrogen 3.149 N/A LYS 167.A N ALA 115.A O no hydrogen 3.058 N/A THR 170.A N LYS 167.A O no hydrogen 3.424 N/A THR 170.A OG1 PRO 112.A O no hydrogen 3.313 N/A THR 170.A OG1 ILE 113.A O no hydrogen 3.361 N/A THR 170.A OG1 ALA 115.A O no hydrogen 3.230 N/A THR 170.A OG1 LYS 167.A O no hydrogen 2.526 N/A THR 172.A N ASP 95.A OD1 no hydrogen 3.260 N/A THR 172.A OG1 ASP 95.A OD1 no hydrogen 2.305 N/A THR 173.A N LEU 156.A O no hydrogen 2.636 N/A THR 173.A OG1 LEU 156.A O no hydrogen 3.498 N/A THR 173.A OG1 HIS 174.A ND1 no hydrogen 2.603 N/A HIS 174.A N LEU 156.A O no hydrogen 2.744 N/A HIS 174.A ND1 THR 173.A OG1 no hydrogen 2.603 N/A ILE 175.A N VAL 218.A O no hydrogen 2.909 N/A LYS 177.A N LEU 216.A O no hydrogen 2.573 N/A LYS 177.A NZ GLU 188.A OE1 no hydrogen 3.151 N/A LEU 178.A N GLU 152.A O no hydrogen 2.994 N/A ILE 180.A N SER 184.A OG no hydrogen 2.910 N/A GLN 183.A N GLN 183.A OE1 no hydrogen 2.525 N/A SER 184.A N SER 182.A O no hydrogen 2.706 N/A SER 184.A OG SER 182.A O no hydrogen 3.509 N/A ASN 187.A N GLN 183.A O no hydrogen 2.896 N/A ASN 187.A ND2 SER 319.A O no hydrogen 2.734 N/A GLU 188.A N SER 184.A O no hydrogen 3.233 N/A TYR 189.A N VAL 185.A O no hydrogen 3.243 N/A TYR 190.A N ASP 186.A O no hydrogen 2.998 N/A CYS 191.A N ASN 187.A O no hydrogen 3.051 N/A CYS 191.A SG ASN 187.A O no hydrogen 3.307 N/A CYS 191.A SG ASN 187.A OD1 no hydrogen 3.396 N/A LEU 192.A N GLU 188.A O no hydrogen 2.558 N/A LEU 194.A N TYR 190.A O no hydrogen 3.051 N/A ALA 195.A N CYS 191.A O no hydrogen 3.163 N/A LYS 196.A N LEU 192.A O no hydrogen 3.190 N/A GLU 197.A N LEU 193.A O no hydrogen 2.950 N/A LEU 198.A N ALA 195.A O no hydrogen 3.142 N/A GLY 199.A N LYS 196.A O no hydrogen 2.547 N/A LEU 200.A N ALA 195.A O no hydrogen 3.182 N/A GLU 206.A N ALA 217.A O no hydrogen 2.856 N/A ILE 208.A N ALA 215.A O no hydrogen 2.683 N/A ALA 210.A N VAL 213.A O no hydrogen 2.887 N/A VAL 213.A N ALA 210.A O no hydrogen 2.972 N/A ALA 215.A N ILE 208.A O no hydrogen 2.964 N/A LEU 216.A N LYS 177.A O no hydrogen 2.605 N/A ALA 217.A N GLU 206.A O no hydrogen 2.563 N/A VAL 218.A N ILE 175.A O no hydrogen 3.403 N/A GLU 219.A N ASP 204.A O no hydrogen 3.361 N/A ARG 220.A N THR 173.A O no hydrogen 2.997 N/A ARG 220.A NE ASP 222.A OD1 no hydrogen 2.997 N/A ARG 220.A NH1 THR 172.A OG1 no hydrogen 3.086 N/A ARG 223.A NE THR 172.A O no hydrogen 3.160 N/A ARG 223.A NH1 ASP 222.A O no hydrogen 2.625 N/A ARG 223.A NH2 ASP 95.A OD2 no hydrogen 2.619 N/A ARG 223.A NH2 SER 96.A O no hydrogen 3.268 N/A ARG 224.A N LEU 233.A O no hydrogen 3.138 N/A ASN 226.A N VAL 231.A O no hydrogen 2.805 N/A ASN 226.A ND2 THR 230.A OG1 no hydrogen 3.068 N/A ARG 229.A N ASN 226.A O no hydrogen 3.323 N/A THR 230.A N ASN 226.A OD1 no hydrogen 2.846 N/A THR 230.A OG1 ASN 226.A OD1 no hydrogen 3.009 N/A VAL 231.A N ASN 226.A OD1 no hydrogen 2.696 N/A LEU 233.A N ARG 224.A O no hydrogen 2.914 N/A ARG 234.A N ASN 8.A OD1 no hydrogen 2.653 N/A LEU 235.A N ASP 222.A O no hydrogen 3.467 N/A GLU 238.A N VAL 301.A O no hydrogen 3.201 N/A ASP 239.A N GLN 242.A OE1 no hydrogen 3.136 N/A MET 240.A N PHE 299.A O no hydrogen 2.928 N/A CYS 241.A N ASP 239.A OD2 no hydrogen 2.721 N/A GLN 242.A N ASP 239.A OD2 no hydrogen 3.136 N/A GLN 242.A NE2 PHE 59.A O no hydrogen 2.869 N/A THR 243.A N ASP 239.A O no hydrogen 3.146 N/A THR 243.A OG1 GLU 238.A OE1 no hydrogen 2.775 N/A THR 243.A OG1 ASP 239.A O no hydrogen 3.529 N/A GLY 245.A N GLN 242.A O no hydrogen 2.478 N/A LEU 246.A N CYS 241.A O no hydrogen 2.833 N/A VAL 250.A N PRO 247.A O no hydrogen 2.745 N/A LYS 251.A N SER 248.A O no hydrogen 3.003 N/A LYS 251.A NZ ASP 66.A OD1 no hydrogen 3.547 N/A LYS 251.A NZ SER 248.A O no hydrogen 2.815 N/A GLY 256.A N TYR 252.A O no hydrogen 3.443 N/A GLY 257.A N TYR 252.A O no hydrogen 3.206 N/A ILE 263.A N GLY 259.A O no hydrogen 3.145 N/A MET 264.A N ILE 260.A O no hydrogen 2.721 N/A ALA 265.A N ALA 261.A O no hydrogen 2.650 N/A PHE 266.A N ARG 262.A O no hydrogen 2.870 N/A LEU 267.A N ILE 263.A O no hydrogen 2.988 N/A LEU 267.A N MET 264.A O no hydrogen 3.222 N/A SER 269.A N LEU 267.A O no hydrogen 2.860 N/A SER 269.A OG ASP 275.A OD2 no hydrogen 2.918 N/A SER 269.A OG TYR 309.A O no hydrogen 3.188 N/A SER 270.A N TYR 309.A O no hydrogen 3.270 N/A GLU 271.A N SER 269.A OG no hydrogen 2.754 N/A ASP 275.A N GLU 271.A O no hydrogen 2.826 N/A ARG 276.A N ALA 272.A O no hydrogen 2.604 N/A ARG 276.A NH2 LEU 365.A O no hydrogen 3.040 N/A TYR 277.A N LYS 274.A O no hydrogen 2.837 N/A ASP 278.A N LYS 274.A O no hydrogen 2.955 N/A PHE 279.A N ASP 275.A O no hydrogen 2.908 N/A LYS 281.A N TYR 277.A O no hydrogen 3.188 N/A LYS 281.A NZ GLY 199.A O no hydrogen 2.618 N/A PHE 282.A N ASP 278.A O no hydrogen 3.063 N/A GLN 283.A N PHE 279.A O no hydrogen 3.138 N/A GLN 283.A NE2 PHE 279.A O no hydrogen 3.011 N/A VAL 284.A N MET 280.A O no hydrogen 3.165 N/A PHE 285.A N LYS 281.A O no hydrogen 3.113 N/A PHE 285.A N PHE 282.A O no hydrogen 2.776 N/A GLN 286.A N PHE 282.A O no hydrogen 2.794 N/A GLN 286.A NE2 GLN 283.A OE1 no hydrogen 3.650 N/A TRP 287.A N GLN 283.A O no hydrogen 3.126 N/A LEU 288.A N VAL 284.A O no hydrogen 3.215 N/A ILE 289.A N PHE 285.A O no hydrogen 2.937 N/A GLY 290.A N TRP 287.A O no hydrogen 2.609 N/A ALA 291.A N GLN 286.A O no hydrogen 2.880 N/A HIS 295.A N GLN 293.A O no hydrogen 2.460 N/A ALA 296.A N LYS 251.A O no hydrogen 3.023 N/A LYS 297.A NZ ASN 62.A O no hydrogen 3.185 N/A LYS 297.A NZ ASN 62.A OD1 no hydrogen 2.701 N/A LYS 297.A NZ ASP 239.A OD1 no hydrogen 2.455 N/A ASN 298.A N HIS 295.A O no hydrogen 2.661 N/A ASN 298.A ND2 ASP 316.A OD2 no hydrogen 2.499 N/A PHE 299.A N ALA 296.A O no hydrogen 3.003 N/A SER 300.A OG GLU 238.A O no hydrogen 2.880 N/A SER 300.A OG TYR 315.A OH no hydrogen 3.262 N/A VAL 301.A N GLU 238.A O no hydrogen 3.087 N/A PHE 302.A N ARG 310.A O no hydrogen 2.836 N/A ILE 303.A N PRO 236.A O no hydrogen 3.166 N/A GLN 304.A N SER 308.A O no hydrogen 3.125 N/A GLN 304.A NE2 SER 270.A OG no hydrogen 3.132 N/A GLY 306.A N ALA 37.A O no hydrogen 3.021 N/A SER 308.A N ALA 305.A O no hydrogen 3.460 N/A TYR 309.A OH PHE 266.A O no hydrogen 2.922 N/A LEU 311.A N ASP 275.A OD1 no hydrogen 3.293 N/A THR 312.A N SER 300.A O no hydrogen 2.477 N/A THR 312.A OG1 SER 300.A O no hydrogen 2.923 N/A THR 312.A OG1 PRO 313.A O no hydrogen 3.252 N/A PHE 314.A N ASN 201.A O no hydrogen 2.403 N/A TYR 315.A OH LYS 297.A O no hydrogen 3.424 N/A TYR 315.A OH SER 300.A OG no hydrogen 3.262 N/A SER 319.A N ASN 187.A OD1 no hydrogen 2.459 N/A ALA 320.A N GLY 290.A O no hydrogen 2.822 N/A PHE 321.A N SER 319.A OG no hydrogen 3.253 N/A LEU 324.A N PHE 321.A O no hydrogen 2.852 N/A HIS 330.A N ASP 333.A OD2 no hydrogen 2.825 N/A SER 332.A OG HIS 330.A O no hydrogen 3.483 N/A SER 332.A OG ASP 333.A OD2 no hydrogen 3.112 N/A ASP 333.A N HIS 330.A O no hydrogen 2.367 N/A LEU 336.A N THR 348.A O no hydrogen 3.054 N/A GLY 339.A N GLU 253.A OE1 no hydrogen 2.934 N/A ASN 341.A N THR 361.A OG1 no hydrogen 2.816 N/A LYS 346.A NZ GLU 253.A OE2 no hydrogen 2.595 N/A THR 348.A OG1 LEU 336.A O no hydrogen 3.237 N/A THR 348.A OG1 THR 348.A O no hydrogen 2.486 N/A ILE 350.A N LEU 334.A O no hydrogen 3.364 N/A ILE 353.A N ILE 350.A O no hydrogen 2.964 N/A HIS 357.A N TYR 354.A O no hydrogen 2.570 N/A PHE 358.A N PRO 355.A O no hydrogen 2.863 N/A LEU 359.A N PRO 355.A O no hydrogen 3.326 N/A ALA 360.A N HIS 357.A O no hydrogen 3.295 N/A THR 361.A N HIS 357.A O no hydrogen 3.246 N/A THR 361.A OG1 ASN 341.A O no hydrogen 3.256 N/A THR 361.A OG1 HIS 357.A O no hydrogen 2.834 N/A ALA 362.A N PHE 358.A O no hydrogen 2.664 N/A LYS 363.A N ALA 360.A O no hydrogen 2.943 N/A VAL 364.A N ALA 360.A O no hydrogen 3.091 N/A VAL 364.A N THR 361.A O no hydrogen 3.035 N/A LEU 365.A N THR 361.A O no hydrogen 3.166 N/A ARG 366.A NE VAL 364.A O no hydrogen 3.521 N/A ARG 366.A NH2 VAL 364.A O no hydrogen 3.436 N/A GLN 371.A N PRO 368.A O no hydrogen 2.718 N/A MET 372.A N PRO 368.A O no hydrogen 3.196 N/A HIS 373.A N GLU 369.A O no hydrogen 2.931 N/A HIS 373.A ND1 TYR 420.A OH no hydrogen 2.917 N/A HIS 373.A NE2 GLU 369.A OE1 no hydrogen 2.704 N/A GLU 374.A N VAL 370.A O no hydrogen 3.396 N/A ILE 375.A N GLN 371.A O no hydrogen 3.160 N/A ILE 375.A N MET 372.A O no hydrogen 3.122 N/A LEU 376.A N MET 372.A O no hydrogen 3.021 N/A SER 377.A N HIS 373.A O no hydrogen 2.978 N/A SER 377.A OG ASP 378.A OD2 no hydrogen 3.522 N/A ASP 378.A N GLU 374.A O no hydrogen 2.946 N/A PHE 379.A N ILE 375.A O no hydrogen 3.369 N/A ALA 380.A N LEU 376.A O no hydrogen 2.826 N/A ARG 381.A N ASP 378.A O no hydrogen 3.452 N/A LEU 386.A N ILE 382.A O no hydrogen 2.755 N/A ASP 387.A N PRO 383.A O no hydrogen 2.965 N/A ASN 388.A N ALA 384.A O no hydrogen 2.917 N/A ASN 388.A ND2 ALA 384.A O no hydrogen 2.556 N/A VAL 389.A N LEU 386.A O no hydrogen 2.949 N/A LYS 390.A N LEU 386.A O no hydrogen 2.894 N/A THR 391.A N ASP 387.A O no hydrogen 3.039 N/A THR 391.A OG1 ASP 387.A O no hydrogen 3.005 N/A SER 392.A N VAL 389.A O no hydrogen 2.554 N/A LEU 393.A N VAL 389.A O no hydrogen 3.411 N/A PHE 397.A N PRO 394.A O no hydrogen 2.538 N/A THR 403.A N GLU 399.A O no hydrogen 3.228 N/A THR 403.A OG1 GLU 399.A O no hydrogen 2.780 N/A ALA 404.A N ASN 400.A O no hydrogen 2.265 N/A VAL 405.A N VAL 401.A O no hydrogen 2.839 N/A GLU 406.A N VAL 402.A O no hydrogen 2.522 N/A SER 407.A N THR 403.A O no hydrogen 2.739 N/A ASN 408.A ND2 ALA 404.A O no hydrogen 2.635 N/A VAL 409.A N VAL 405.A O no hydrogen 3.277 N/A LEU 410.A N GLU 406.A O no hydrogen 3.334 N/A ARG 411.A N SER 407.A O no hydrogen 3.119 N/A ARG 411.A NH1 ASP 351.A OD2 no hydrogen 3.338 N/A ARG 411.A NH2 ASP 351.A OD2 no hydrogen 3.132 N/A LEU 412.A N ASN 408.A O no hydrogen 3.027 N/A HIS 413.A N VAL 409.A O no hydrogen 2.873 N/A HIS 413.A NE2 ALA 380.A O no hydrogen 3.184 N/A GLY 414.A N LEU 410.A O no hydrogen 2.873 N/A GLY 414.A N ARG 411.A O no hydrogen 2.969 N/A ARG 415.A N LEU 412.A O no hydrogen 3.210 N/A LEU 416.A N HIS 413.A O no hydrogen 2.568 N/A SER 417.A N HIS 413.A O no hydrogen 3.353 N/A SER 417.A OG GLY 414.A O no hydrogen 3.091 N/A ARG 418.A N GLY 414.A O no hydrogen 2.970 N/A GLU 419.A N LEU 416.A O no hydrogen 2.501 N/A TYR 420.A N LEU 416.A O no hydrogen 2.727 N/A TYR 420.A OH HIS 373.A ND1 no hydrogen 2.917 N/A