Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3l2r_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N ALA 1.A O no hydrogen 3.235 N/A LEU 6.A N LEU 3.A O no hydrogen 3.303 N/A GLY 9.A N LEU 6.A O no hydrogen 2.744 N/A TYR 15.A N ILE 12.A O no hydrogen 2.890 N/A LYS 17.A NZ GLY 9.A O no hydrogen 3.548 N/A TYR 21.A OH PRO 16.A O no hydrogen 2.335 N/A PHE 22.A N LYS 29.A O no hydrogen 2.879 N/A GLU 24.A N LYS 27.A O no hydrogen 3.103 N/A LYS 27.A N GLU 24.A O no hydrogen 2.953 N/A LYS 29.A N PHE 22.A O no hydrogen 2.677 N/A LYS 29.A NZ GLU 24.A OE1 no hydrogen 3.347 N/A LYS 29.A NZ ASP 25.A OD2 no hydrogen 3.449 N/A VAL 30.A N LYS 37.A O no hydrogen 2.895 N/A SER 31.A N THR 20.A O no hydrogen 3.480 N/A ARG 32.A N GLY 35.A O no hydrogen 2.633 N/A LYS 37.A N VAL 30.A O no hydrogen 2.888 N/A ILE 38.A N LEU 70.A O no hydrogen 2.901 N/A ILE 39.A N VAL 28.A O no hydrogen 2.929 N/A ASP 44.A N PRO 41.A O no hydrogen 3.043 N/A ARG 45.A N GLN 42.A O no hydrogen 3.344 N/A ARG 45.A NE PRO 40.A O no hydrogen 2.963 N/A ARG 45.A NH2 TYR 15.A OH no hydrogen 2.727 N/A ARG 45.A NH2 PRO 40.A O no hydrogen 2.902 N/A ILE 48.A N ASP 44.A O no hydrogen 2.999 N/A VAL 49.A N ARG 45.A O no hydrogen 2.955 N/A LEU 50.A N GLN 46.A O no hydrogen 3.041 N/A GLN 51.A N LYS 47.A O no hydrogen 2.976 N/A ALA 52.A N ILE 48.A O no hydrogen 3.032 N/A HIS 53.A N VAL 49.A O no hydrogen 2.880 N/A HIS 53.A ND1 THR 58.A O no hydrogen 2.733 N/A ASN 54.A N LEU 50.A O no hydrogen 2.834 N/A LEU 55.A N ALA 52.A O no hydrogen 3.296 N/A HIS 57.A ND1 HIS 53.A NE2 no hydrogen 3.094 N/A THR 58.A OG1 THR 63.A OG1 no hydrogen 2.863 N/A ARG 60.A NH1 GLU 61.A OE2 no hydrogen 3.038 N/A THR 63.A N GLY 59.A O no hydrogen 2.882 N/A THR 63.A OG1 THR 58.A OG1 no hydrogen 2.863 N/A THR 63.A OG1 GLY 59.A O no hydrogen 2.504 N/A LEU 64.A N ARG 60.A O no hydrogen 2.767 N/A LEU 65.A N GLU 61.A O no hydrogen 2.724 N/A LYS 66.A N THR 63.A O no hydrogen 3.218 N/A ILE 67.A N THR 63.A O no hydrogen 3.307 N/A ALA 68.A N LEU 64.A O no hydrogen 2.898 N/A ASN 69.A N LYS 66.A O no hydrogen 2.719 N/A LEU 70.A N ILE 67.A O no hydrogen 3.042 N/A TYR 71.A N ILE 67.A O no hydrogen 2.860 N/A TRP 72.A N ILE 38.A O no hydrogen 2.893 N/A TRP 73.A NE1 ASP 79.A OD2 no hydrogen 2.788 N/A ARG 77.A NE GLU 61.A OE2 no hydrogen 2.667 N/A ARG 77.A NH2 GLU 61.A OE1 no hydrogen 2.434 N/A ARG 77.A NH2 GLU 61.A OE2 no hydrogen 2.806 N/A VAL 80.A N MET 76.A O no hydrogen 2.851 N/A VAL 81.A N ARG 77.A O no hydrogen 2.732 N/A LYS 82.A N LYS 78.A O no hydrogen 3.190 N/A GLN 83.A N ASP 79.A O no hydrogen 3.398 N/A LEU 84.A N VAL 80.A O no hydrogen 3.224 N/A GLY 85.A N VAL 81.A O no hydrogen 3.182 N/A ARG 86.A N GLN 83.A O no hydrogen 2.616 N/A CYS 87.A N LEU 84.A O no hydrogen 3.291 N/A CYS 87.A SG HIS 53.A NE2 no hydrogen 3.472 N/A CYS 87.A SG HIS 57.A ND1 no hydrogen 3.471 N/A CYS 87.A SG GLN 89.A OE1 no hydrogen 3.864 N/A GLN 89.A N GLN 89.A OE1 no hydrogen 2.906 N/A CYS 90.A SG HIS 53.A NE2 no hydrogen 3.297 N/A CYS 90.A SG HIS 57.A ND1 no hydrogen 3.679 N/A CYS 90.A SG HIS 57.A O no hydrogen 3.577 N/A LEU 91.A N CYS 87.A O no hydrogen 2.954 N/A ILE 92.A N GLN 88.A O no hydrogen 3.125 N/A THR 93.A OG1 GLN 89.A O no hydrogen 2.562 N/A ASN 94.A N CYS 90.A O no hydrogen 3.113 N/A SER 96.A OG LYS 98.A O no hydrogen 3.281 N/A LYS 98.A N SER 96.A OG no hydrogen 3.143 N/A LYS 98.A NZ ASN 97.A OD1 no hydrogen 2.896 N/A ALA 99.A N ARG 304.A O no hydrogen 3.213 N/A SER 100.A OG ASP 358.A OD1 no hydrogen 2.631 N/A ARG 108.A NH1 MET 140.A O no hydrogen 3.016 N/A LYS 111.A N ASP 114.A OD2 no hydrogen 3.036 N/A PHE 113.A N ASP 138.A OD1 no hydrogen 2.885 N/A ASP 114.A N LYS 111.A O no hydrogen 3.192 N/A LYS 115.A NZ GLU 198.A OE1 no hydrogen 3.314 N/A LYS 115.A NZ GLU 198.A OE2 no hydrogen 2.834 N/A PHE 116.A N VAL 172.A O no hydrogen 2.689 N/A PHE 117.A N VAL 137.A O no hydrogen 2.875 N/A ILE 118.A N HIS 174.A O no hydrogen 2.983 N/A ASP 119.A N VAL 135.A O no hydrogen 3.049 N/A TYR 120.A OH THR 157.A OG1 no hydrogen 2.576 N/A ILE 121.A N VAL 133.A O no hydrogen 2.940 N/A LEU 124.A N LEU 131.A O no hydrogen 2.795 N/A SER 127.A N TYR 130.A O no hydrogen 3.024 N/A TYR 130.A N SER 127.A O no hydrogen 2.719 N/A LEU 131.A N THR 149.A O no hydrogen 2.895 N/A TYR 132.A N THR 149.A O no hydrogen 2.837 N/A VAL 133.A N ILE 121.A O no hydrogen 2.946 N/A LEU 134.A N TYR 147.A O no hydrogen 2.569 N/A VAL 135.A N ASP 119.A O no hydrogen 2.821 N/A VAL 136.A N TRP 145.A O no hydrogen 3.129 N/A VAL 137.A N PHE 117.A O no hydrogen 2.752 N/A ASP 138.A N PHE 143.A O no hydrogen 2.790 N/A GLY 139.A N LYS 115.A O no hydrogen 2.879 N/A THR 141.A N ASP 138.A OD2 no hydrogen 3.037 N/A THR 141.A OG1 ASP 138.A OD2 no hydrogen 2.558 N/A GLY 142.A N ASP 138.A O no hydrogen 2.783 N/A PHE 143.A N THR 141.A OG1 no hydrogen 3.020 N/A THR 144.A N ASN 245.A OD1 no hydrogen 2.951 N/A THR 144.A OG1 GLY 142.A O no hydrogen 3.258 N/A TRP 145.A N VAL 136.A O no hydrogen 2.929 N/A LEU 146.A N GLN 241.A OE1 no hydrogen 2.831 N/A TYR 147.A N LEU 134.A O no hydrogen 2.911 N/A THR 149.A N TYR 132.A O no hydrogen 2.730 N/A THR 149.A OG1 ALA 151.A O no hydrogen 2.664 N/A THR 154.A OG1 ALA 180.A O no hydrogen 3.010 N/A THR 154.A OG1 SER 183.A OG no hydrogen 2.922 N/A ALA 156.A N SER 153.A OG no hydrogen 3.248 N/A THR 157.A N SER 153.A O no hydrogen 3.019 N/A THR 157.A OG1 TYR 120.A OH no hydrogen 2.576 N/A THR 157.A OG1 SER 153.A O no hydrogen 2.397 N/A VAL 158.A N THR 154.A O no hydrogen 2.807 N/A LYS 159.A N SER 155.A O no hydrogen 2.871 N/A SER 160.A N ALA 156.A O no hydrogen 2.923 N/A SER 160.A OG ALA 156.A O no hydrogen 2.960 N/A LEU 161.A N THR 157.A O no hydrogen 2.817 N/A ASN 162.A N VAL 158.A O no hydrogen 2.916 N/A VAL 163.A N SER 160.A O no hydrogen 3.146 N/A LEU 164.A N SER 160.A O no hydrogen 3.257 N/A THR 165.A N LEU 161.A O no hydrogen 2.794 N/A THR 165.A OG1 LEU 161.A O no hydrogen 2.761 N/A SER 166.A OG VAL 163.A O no hydrogen 2.828 N/A ILE 167.A N LEU 164.A O no hydrogen 2.781 N/A LYS 171.A N PHE 113.A O no hydrogen 2.874 N/A LYS 171.A NZ ASP 114.A OD1 no hydrogen 2.699 N/A VAL 172.A N ASP 114.A O no hydrogen 3.109 N/A ILE 173.A N HIS 196.A O no hydrogen 3.020 N/A HIS 174.A N PHE 116.A O no hydrogen 2.616 N/A HIS 174.A ND1 GLU 198.A OE2 no hydrogen 2.772 N/A HIS 174.A NE2 SER 200.A OG no hydrogen 3.062 N/A SER 175.A N GLU 198.A O no hydrogen 3.107 N/A SER 175.A OG ASP 176.A O no hydrogen 2.714 N/A GLN 177.A NE2 SER 200.A O no hydrogen 2.983 N/A GLY 178.A N ASP 176.A OD2 no hydrogen 2.663 N/A PHE 181.A N GLY 178.A O no hydrogen 2.875 N/A THR 182.A OG1 GLN 177.A O no hydrogen 3.378 N/A THR 182.A OG1 GLY 178.A O no hydrogen 2.823 N/A SER 183.A OG THR 154.A OG1 no hydrogen 2.922 N/A PHE 186.A N SER 183.A OG no hydrogen 3.103 N/A ALA 187.A N SER 183.A O no hydrogen 3.302 N/A GLU 188.A N SER 184.A O no hydrogen 3.022 N/A TRP 189.A N THR 185.A O no hydrogen 3.057 N/A TRP 189.A NE1 ASN 162.A OD1 no hydrogen 2.703 N/A ALA 190.A N PHE 186.A O no hydrogen 2.963 N/A LYS 191.A N ALA 187.A O no hydrogen 2.786 N/A GLU 192.A N GLU 188.A O no hydrogen 2.865 N/A ARG 193.A N ALA 190.A O no hydrogen 3.082 N/A ARG 193.A NH1 TRP 189.A O no hydrogen 2.980 N/A ARG 193.A NH1 GLU 192.A OE1 no hydrogen 3.406 N/A GLY 194.A N LYS 191.A O no hydrogen 3.351 N/A ILE 195.A N ALA 190.A O no hydrogen 3.186 N/A HIS 196.A N LYS 171.A O no hydrogen 2.705 N/A GLU 198.A N ILE 173.A O no hydrogen 3.026 N/A SER 200.A N SER 175.A O no hydrogen 2.872 N/A SER 200.A OG HIS 174.A NE2 no hydrogen 3.062 N/A SER 200.A OG SER 175.A O no hydrogen 3.235 N/A SER 200.A OG SER 208.A OG no hydrogen 3.194 N/A HIS 204.A ND1 SER 207.A OG no hydrogen 2.864 N/A HIS 204.A NE2 ASP 358.A OD2 no hydrogen 2.997 N/A GLN 206.A N GLN 206.A OE1 no hydrogen 2.828 N/A SER 207.A N HIS 204.A O no hydrogen 3.306 N/A SER 207.A OG HIS 204.A ND1 no hydrogen 2.864 N/A SER 208.A N PRO 205.A O no hydrogen 2.811 N/A SER 208.A OG SER 200.A OG no hydrogen 3.194 N/A GLY 209.A N GLN 206.A O no hydrogen 3.006 N/A VAL 211.A N SER 208.A O no hydrogen 2.808 N/A GLU 212.A N SER 208.A O no hydrogen 2.974 N/A ARG 213.A N GLY 209.A O no hydrogen 2.721 N/A ARG 213.A NH1 ARG 213.A O no hydrogen 3.269 N/A ARG 213.A NH1 ASP 217.A OD1 no hydrogen 3.156 N/A LYS 214.A N LYS 210.A O no hydrogen 3.274 N/A LYS 214.A NZ GLY 142.A O no hydrogen 3.329 N/A ASN 215.A N VAL 211.A O no hydrogen 2.768 N/A ASN 215.A N GLU 212.A O no hydrogen 2.859 N/A ASN 215.A ND2 ASP 119.A OD2 no hydrogen 3.366 N/A ASN 215.A ND2 GLU 212.A OE1 no hydrogen 3.257 N/A SER 216.A N GLU 212.A O no hydrogen 3.237 N/A ILE 218.A N LYS 214.A O no hydrogen 3.168 N/A LYS 219.A N ASN 215.A O no hydrogen 2.898 N/A ARG 220.A N SER 216.A O no hydrogen 2.838 N/A ARG 220.A NH2 ASP 217.A OD1 no hydrogen 3.051 N/A LEU 221.A N ASP 217.A O no hydrogen 2.874 N/A LEU 222.A N ILE 218.A O no hydrogen 2.840 N/A THR 223.A N LYS 219.A O no hydrogen 2.822 N/A THR 223.A OG1 LYS 219.A O no hydrogen 2.776 N/A LYS 224.A N ARG 220.A O no hydrogen 3.072 N/A LEU 225.A N LEU 221.A O no hydrogen 2.943 N/A LEU 226.A N THR 223.A O no hydrogen 2.891 N/A VAL 227.A N LYS 224.A O no hydrogen 3.301 N/A LYS 232.A N PRO 230.A O no hydrogen 2.783 N/A TRP 233.A NE1 PRO 125.A O no hydrogen 2.702 N/A TYR 234.A N SER 127.A OG no hydrogen 3.196 N/A LEU 236.A N TRP 233.A O no hydrogen 2.820 N/A LEU 237.A N TRP 233.A O no hydrogen 3.301 N/A VAL 240.A N LEU 236.A O no hydrogen 2.845 N/A GLN 241.A N LEU 237.A O no hydrogen 2.721 N/A LEU 242.A N PRO 238.A O no hydrogen 2.882 N/A ALA 243.A N VAL 239.A O no hydrogen 2.823 N/A LEU 244.A N VAL 240.A O no hydrogen 2.774 N/A ASN 245.A N GLN 241.A O no hydrogen 3.045 N/A ASN 245.A ND2 THR 144.A O no hydrogen 2.945 N/A ASN 246.A N LEU 242.A O no hydrogen 3.078 N/A ASN 246.A ND2 LEU 242.A O no hydrogen 2.919 N/A THR 247.A N LEU 244.A O no hydrogen 3.153 N/A THR 247.A OG1 ALA 243.A O no hydrogen 2.877 N/A SER 249.A N TYR 254.A O no hydrogen 2.932 N/A LEU 252.A N SER 249.A O no hydrogen 2.878 N/A LYS 253.A N SER 249.A O no hydrogen 2.784 N/A THR 255.A N GLN 258.A OE1 no hydrogen 3.080 N/A HIS 257.A N ASN 245.A O no hydrogen 2.827 N/A HIS 257.A NE2 ILE 263.A O no hydrogen 2.729 N/A GLN 258.A N THR 255.A OG1 no hydrogen 3.017 N/A GLN 258.A NE2 TYR 248.A OH no hydrogen 3.381 N/A GLN 258.A NE2 ASP 264.A OD1 no hydrogen 2.770 N/A GLN 258.A NE2 ASP 264.A OD2 no hydrogen 3.084 N/A LEU 259.A N THR 255.A O no hydrogen 2.984 N/A LEU 260.A N PRO 256.A O no hydrogen 2.810 N/A PHE 261.A N HIS 257.A O no hydrogen 2.845 N/A GLY 262.A N GLN 258.A O no hydrogen 2.687 N/A ASN 271.A N ASP 264.A OD2 no hydrogen 2.780 N/A ASN 271.A ND2 ASP 273.A OD2 no hydrogen 3.029 N/A ASP 273.A N ASN 271.A OD1 no hydrogen 2.956 N/A THR 274.A OG1 GLU 282.A OE2 no hydrogen 2.517 N/A LEU 275.A N GLN 272.A O no hydrogen 3.010 N/A LEU 277.A N THR 274.A O no hydrogen 3.203 N/A THR 278.A N GLU 281.A OE1 no hydrogen 2.994 N/A ARG 279.A NH1 PHE 261.A O no hydrogen 3.187 N/A ARG 279.A NH1 GLU 282.A OE1 no hydrogen 2.955 N/A ARG 279.A NH2 PHE 261.A O no hydrogen 2.892 N/A GLU 281.A N THR 278.A OG1 no hydrogen 3.118 N/A GLU 282.A N THR 278.A O no hydrogen 2.944 N/A LEU 283.A N ARG 279.A O no hydrogen 2.758 N/A SER 284.A N GLU 280.A O no hydrogen 3.175 N/A SER 284.A N GLU 281.A O no hydrogen 3.163 N/A SER 284.A OG GLU 281.A O no hydrogen 3.225 N/A LEU 285.A N GLU 281.A O no hydrogen 2.992 N/A LEU 286.A N GLU 282.A O no hydrogen 2.910 N/A GLN 287.A N LEU 283.A O no hydrogen 3.225 N/A GLU 288.A N SER 284.A O no hydrogen 3.157 N/A ILE 289.A N LEU 285.A O no hydrogen 2.873 N/A ARG 290.A N LEU 286.A O no hydrogen 2.939 N/A ARG 290.A NE LEU 259.A O no hydrogen 3.019 N/A ARG 290.A NH2 LEU 259.A O no hydrogen 2.713 N/A THR 291.A OG1 GLU 288.A O no hydrogen 3.377 N/A SER 292.A OG GLU 288.A O no hydrogen 3.258 N/A SER 292.A OG ILE 289.A O no hydrogen 3.179 N/A HIS 295.A NE2 ARG 105.A O no hydrogen 2.830 N/A SER 305.A OG SER 302.A O no hydrogen 3.524 N/A TRP 306.A N ALA 99.A O no hydrogen 2.981 N/A VAL 309.A N GLN 312.A OE1 no hydrogen 3.031 N/A GLY 311.A N VAL 334.A O no hydrogen 3.006 N/A GLN 312.A N VAL 309.A O no hydrogen 3.102 N/A VAL 314.A N SER 332.A O no hydrogen 2.769 N/A GLN 315.A N LYS 361.A O no hydrogen 2.768 N/A GLN 315.A NE2 LEU 91.A O no hydrogen 2.966 N/A GLN 315.A NE2 HIS 329.A O no hydrogen 2.977 N/A ARG 317.A N ASN 359.A O no hydrogen 2.844 N/A VAL 318.A N ARG 327.A O no hydrogen 2.735 N/A ARG 327.A NH1 ALA 322.A O no hydrogen 3.202 N/A ARG 327.A NH1 ARG 325.A O no hydrogen 2.961 N/A TRP 328.A N ILE 92.A O no hydrogen 3.030 N/A HIS 329.A N GLU 316.A O no hydrogen 2.839 N/A SER 332.A N VAL 314.A O no hydrogen 2.791 N/A SER 332.A OG VAL 314.A O no hydrogen 3.322 N/A VAL 334.A N GLN 312.A O no hydrogen 3.000 N/A LEU 335.A N VAL 344.A O no hydrogen 2.711 N/A LYS 336.A N VAL 344.A O no hydrogen 3.453 N/A ASN 339.A N THR 342.A O no hydrogen 3.355 N/A ARG 341.A N ASN 339.A OD1 no hydrogen 2.804 N/A ARG 341.A NH1 ASP 358.A OD1 no hydrogen 3.399 N/A ARG 341.A NH2 ASP 358.A OD1 no hydrogen 2.789 N/A THR 342.A N ASN 339.A O no hydrogen 3.248 N/A THR 342.A OG1 ASN 339.A OD1 no hydrogen 2.594 N/A VAL 343.A N VAL 355.A O no hydrogen 2.887 N/A VAL 344.A N LYS 336.A O no hydrogen 2.862 N/A ILE 345.A N ARG 353.A O no hydrogen 2.857 N/A LEU 346.A N THR 333.A O no hydrogen 3.105 N/A ASP 347.A N ASN 351.A O no hydrogen 3.117 N/A ASN 351.A N ASP 347.A OD2 no hydrogen 2.680 N/A ARG 353.A N ILE 345.A O no hydrogen 2.996 N/A ARG 353.A NE GLU 316.A OE1 no hydrogen 3.325 N/A ARG 353.A NH2 GLU 316.A OE1 no hydrogen 3.504 N/A ARG 353.A NH2 GLU 316.A OE2 no hydrogen 2.429 N/A VAL 355.A N VAL 343.A O no hydrogen 2.819 N/A ILE 357.A N ARG 341.A O no hydrogen 3.054 N/A ASN 359.A N SER 356.A O no hydrogen 2.997 N/A ASN 359.A ND2 PRO 202.A O no hydrogen 3.124 N/A ASN 359.A ND2 TYR 203.A O no hydrogen 2.843 N/A LEU 360.A N ILE 357.A O no hydrogen 2.876 N/A LYS 361.A N GLN 315.A O no hydrogen 3.054 N/A LYS 361.A NZ LEU 91.A O no hydrogen 3.114 N/A LYS 361.A NZ ASN 94.A O no hydrogen 2.836 N/A THR 363.A N LEU 313.A O no hydrogen 3.074 N/A THR 363.A OG1 LEU 313.A O no hydrogen 3.490 N/A THR 363.A OG1 GLN 315.A OE1 no hydrogen 3.058 N/A