Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3lot_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 1.A N ASP 2.A OD1.A no hydrogen 3.548 N/A VAL 4.A N ARG 279.A O no hydrogen 2.857 N/A ILE 5.A N ASP 243.A OD1 no hydrogen 2.847 N/A THR 7.A N VAL 244.A O no hydrogen 2.928 N/A CYS 8.A SG ASN 263.A OD1 no hydrogen 3.259 N/A ALA 9.A N VAL 246.A O no hydrogen 2.793 N/A ILE 10.A N HIS 44.A O no hydrogen 3.004 N/A THR 11.A OG1 PRO 23.A O no hydrogen 2.581 N/A HIS 15.A ND1 LEU 248.A O no hydrogen 2.829 N/A THR 16.A OG1 GLU 130.A OE1 no hydrogen 2.723 N/A SER 18.A N GLU 130.A OE1 no hydrogen 2.860 N/A SER 18.A OG GLU 130.A OE1 no hydrogen 3.175 N/A SER 18.A OG GLU 130.A OE2 no hydrogen 2.535 N/A TYR 21.A N SER 19.A OG no hydrogen 3.040 N/A LEU 22.A N SER 19.A O no hydrogen 3.256 N/A VAL 24.A N GLN 28.A OE1 no hydrogen 2.778 N/A THR 25.A N GLN 28.A OE1 no hydrogen 3.101 N/A GLN 28.A N THR 25.A OG1 no hydrogen 3.018 N/A ILE 29.A N THR 25.A O no hydrogen 2.955 N/A VAL 30.A N PRO 26.A O no hydrogen 3.009 N/A GLU 31.A N ASP 27.A O no hydrogen 3.013 N/A GLU 32.A N GLN 28.A O no hydrogen 2.935 N/A ALA 33.A N ILE 29.A O no hydrogen 2.975 N/A VAL 34.A N VAL 30.A O no hydrogen 3.009 N/A LYS 35.A N GLU 31.A O no hydrogen 2.993 N/A ALA 36.A N GLU 32.A O no hydrogen 2.838 N/A ALA 37.A N ALA 33.A O no hydrogen 2.955 N/A GLU 38.A N VAL 34.A O no hydrogen 2.934 N/A ALA 39.A N LYS 35.A O no hydrogen 3.081 N/A ALA 39.A N ALA 36.A O no hydrogen 3.060 N/A GLY 40.A N ALA 37.A O no hydrogen 3.109 N/A ALA 41.A N ALA 36.A O no hydrogen 3.073 N/A HIS 44.A N CYS 8.A O no hydrogen 2.851 N/A HIS 44.A ND1 ASN 78.A OD1 no hydrogen 2.965 N/A HIS 44.A NE2 HIS 46.A NE2 no hydrogen 3.260 N/A ILE 45.A N ASN 78.A O no hydrogen 2.859 N/A ARG 48.A NE THR 11.A OG1 no hydrogen 2.853 N/A ARG 48.A NH1 HIS 15.A O no hydrogen 3.443 N/A ARG 48.A NH1 GLY 53.A O no hydrogen 2.907 N/A ARG 48.A NH2 THR 11.A O no hydrogen 3.183 N/A ARG 48.A NH2 HIS 15.A O no hydrogen 2.795 N/A ASP 49.A N ARG 54.A O no hydrogen 2.690 N/A LYS 51.A N ASP 49.A OD2 no hydrogen 2.878 N/A ASP 52.A N ASP 49.A OD2 no hydrogen 2.947 N/A GLY 53.A N ASP 49.A O no hydrogen 2.853 N/A ARG 54.A N ASP 52.A OD1 no hydrogen 3.135 N/A ARG 54.A NH2 ASP 52.A OD2 no hydrogen 2.931 N/A THR 56.A N ALA 47.A O no hydrogen 3.271 N/A ASP 58.A N THR 56.A OG1 no hydrogen 3.349 N/A GLU 60.A N ASP 58.A OD1 no hydrogen 2.912 N/A VAL 61.A N ASP 58.A O no hydrogen 2.977 N/A PHE 62.A N ASP 58.A O no hydrogen 3.317 N/A ARG 63.A N VAL 59.A O no hydrogen 2.835 N/A ARG 63.A NE GLU 60.A OE1 no hydrogen 2.807 N/A ARG 63.A NE GLU 60.A OE2 no hydrogen 3.503 N/A ARG 63.A NH1 ALA 100.A O no hydrogen 3.332 N/A ARG 63.A NH2 GLU 60.A OE2 no hydrogen 3.045 N/A TYR 64.A N GLU 60.A O no hydrogen 3.270 N/A TYR 64.A OH ASP 27.A OD1 no hydrogen 2.402 N/A ILE 65.A N VAL 61.A O no hydrogen 3.087 N/A CYS 66.A N PHE 62.A O no hydrogen 3.025 N/A CYS 66.A SG PHE 62.A O no hydrogen 3.289 N/A ARG 67.A N ARG 63.A O no hydrogen 2.981 N/A ARG 67.A NE GLU 68.A OE2 no hydrogen 3.232 N/A ARG 67.A NH2 GLU 68.A OE2 no hydrogen 3.124 N/A GLU 68.A N TYR 64.A O no hydrogen 2.843 N/A ILE 69.A N ILE 65.A O no hydrogen 2.913 N/A LYS 70.A N CYS 66.A O no hydrogen 3.007 N/A LYS 70.A NZ LYS 295.A O no hydrogen 3.097 N/A LYS 70.A NZ PHE 300.A O no hydrogen 2.925 N/A LYS 71.A N ARG 67.A O no hydrogen 3.035 N/A LYS 71.A NZ GLU 68.A OE2 no hydrogen 3.067 N/A GLN 72.A N ILE 69.A O no hydrogen 2.915 N/A VAL 75.A N SER 73.A OG no hydrogen 2.995 N/A VAL 76.A N GLY 42.A O no hydrogen 3.140 N/A ASN 78.A N VAL 43.A O no hydrogen 2.791 N/A VAL 79.A N.A ILE 105.A O no hydrogen 3.253 N/A VAL 79.A N.B ILE 105.A O no hydrogen 3.261 N/A THR 80.A N ILE 45.A O no hydrogen 3.116 N/A THR 80.A OG1 THR 107.A OG1 no hydrogen 3.361 N/A THR 81.A N THR 107.A OG1 no hydrogen 2.876 N/A THR 81.A OG1 THR 107.A O no hydrogen 2.622 N/A GLY 82.A N THR 80.A OG1 no hydrogen 2.900 N/A GLY 83.A N THR 80.A OG1 no hydrogen 3.036 N/A GLY 85.A N GLY 82.A O no hydrogen 2.937 N/A THR 86.A OG1 TYR 133.A OH no hydrogen 2.736 N/A LEU 87.A N GLY 84.A O no hydrogen 2.875 N/A GLY 88.A N GLY 85.A O no hydrogen 2.944 N/A ILE 89.A N GLY 84.A O no hydrogen 3.115 N/A GLU 93.A N PRO 90.A O no hydrogen 3.033 N/A ARG 94.A N.A PRO 90.A O no hydrogen 3.035 N/A ARG 94.A N.B PRO 90.A O no hydrogen 3.036 N/A ARG 94.A NE.A ILE 89.A O no hydrogen 2.787 N/A ARG 94.A NE.B THR 81.A O no hydrogen 2.775 N/A ARG 94.A NH1.A THR 81.A O no hydrogen 2.768 N/A ARG 94.A NH1.A ASN 143.A OD1 no hydrogen 3.251 N/A ARG 94.A NH1.B ILE 89.A O no hydrogen 2.813 N/A ARG 94.A NH1.B ARG 142.A O no hydrogen 3.531 N/A ARG 94.A NH2.A ILE 89.A O no hydrogen 3.530 N/A ARG 94.A NH2.A ARG 142.A O no hydrogen 2.680 N/A ARG 94.A NH2.A ASN 143.A OD1 no hydrogen 3.365 N/A ARG 94.A NH2.B THR 81.A O no hydrogen 3.329 N/A ARG 94.A NH2.B ASN 143.A OD1 no hydrogen 2.688 N/A ALA 95.A N VAL 91.A O no hydrogen 2.782 N/A LYS 96.A N GLU 93.A O no hydrogen 3.333 N/A LYS 96.A NZ GLU 93.A OE1 no hydrogen 2.944 N/A VAL 98.A N ALA 95.A O no hydrogen 2.949 N/A ALA 100.A N LYS 96.A O no hydrogen 3.233 N/A LEU 101.A N VAL 97.A O no hydrogen 2.912 N/A LYS 102.A N VAL 98.A O no hydrogen 2.771 N/A LYS 102.A NZ PRO 99.A O no hydrogen 3.015 N/A LYS 102.A NZ ASN 158.A OD1 no hydrogen 2.817 N/A ALA 106.A N LYS 161.A O no hydrogen 3.113 N/A THR 107.A N VAL 79.A O.A no hydrogen 3.106 N/A THR 107.A N VAL 79.A O.B no hydrogen 2.975 N/A THR 107.A OG1 THR 80.A OG1 no hydrogen 3.361 N/A PHE 108.A N GLU 163.A O no hydrogen 2.889 N/A ALA 114.A N LEU 196.A O no hydrogen 2.939 N/A ILE 115.A N THR 136.A OG1 no hydrogen 3.012 N/A LEU 118.A N ILE 115.A O no hydrogen 2.980 N/A LEU 119.A N HIS 116.A O no hydrogen 3.091 N/A LYS 120.A N PRO 117.A O no hydrogen 2.981 N/A LYS 121.A N LEU 118.A O no hydrogen 3.041 N/A LYS 121.A NZ TYR 122.A OH no hydrogen 3.124 N/A LYS 121.A NZ TYR 253.A OH no hydrogen 2.549 N/A TYR 122.A N LEU 118.A O no hydrogen 3.042 N/A LYS 123.A NZ LEU 119.A O no hydrogen 2.925 N/A LYS 126.A N SER 18.A OG no hydrogen 2.832 N/A LYS 126.A NZ TYR 127.A OH no hydrogen 3.248 N/A TYR 127.A N GLU 130.A OE2 no hydrogen 3.073 N/A TRP 129.A NE1 ASP 52.A O no hydrogen 2.902 N/A GLU 130.A N TYR 127.A O no hydrogen 3.267 N/A TYR 133.A N TRP 129.A O no hydrogen 2.814 N/A TYR 133.A OH ALA 13.A O no hydrogen 2.585 N/A TYR 133.A OH THR 86.A OG1 no hydrogen 2.736 N/A LEU 134.A N GLU 130.A O no hydrogen 3.077 N/A GLU 135.A N PRO 131.A O no hydrogen 3.024 N/A THR 136.A OG1 LEU 134.A O no hydrogen 2.608 N/A ARG 137.A N GLU 135.A O no hydrogen 3.045 N/A ARG 137.A NE GLU 135.A OE2 no hydrogen 2.905 N/A ARG 137.A NH2 GLU 135.A OE1 no hydrogen 2.942 N/A ARG 137.A NH2 GLU 135.A OE2 no hydrogen 3.487 N/A ASN 143.A N SER 111.A OG no hydrogen 2.870 N/A ASN 143.A ND2 GLY 110.A O no hydrogen 3.029 N/A ASN 143.A ND2 PHE 141.A O no hydrogen 3.491 N/A THR 144.A N ASP 147.A OD2 no hydrogen 3.055 N/A ASP 147.A N THR 144.A OG1 no hydrogen 3.119 N/A LEU 148.A N THR 144.A O no hydrogen 2.794 N/A GLU 149.A N PHE 145.A O no hydrogen 2.856 N/A ALA 150.A N LYS 146.A O no hydrogen 3.144 N/A LEU 151.A N ASP 147.A O no hydrogen 2.709 N/A SER 152.A N LEU 148.A O no hydrogen 2.882 N/A SER 152.A OG LEU 148.A O no hydrogen 3.538 N/A SER 152.A OG GLU 149.A O no hydrogen 2.628 N/A ARG 153.A N GLU 149.A O no hydrogen 3.426 N/A ILE 154.A N ALA 150.A O no hydrogen 3.201 N/A PHE 155.A N LEU 151.A O no hydrogen 2.960 N/A LYS 156.A N SER 152.A O no hydrogen 3.139 N/A LYS 156.A NZ GLY 181.A O no hydrogen 3.533 N/A LYS 156.A NZ TYR 182.A O no hydrogen 3.132 N/A GLU 157.A N ARG 153.A O no hydrogen 2.789 N/A ASN 158.A N PHE 155.A O no hydrogen 3.184 N/A ASN 158.A ND2 ILE 154.A O no hydrogen 2.739 N/A ASP 159.A N LYS 156.A O no hydrogen 3.298 N/A THR 160.A N PHE 155.A O no hydrogen 2.962 N/A THR 160.A OG1 PRO 103.A O no hydrogen 2.933 N/A THR 160.A OG1 ASN 158.A O no hydrogen 3.555 N/A LYS 161.A N GLU 104.A O no hydrogen 3.013 N/A LYS 161.A NZ PRO 186.A O no hydrogen 2.827 N/A GLU 163.A N ALA 106.A O no hydrogen 2.951 N/A LEU 164.A N ARG 188.A O no hydrogen 2.822 N/A GLU 165.A N PHE 108.A O no hydrogen 2.961 N/A CYS 166.A N GLN 190.A O no hydrogen 2.921 N/A CYS 166.A SG LEU 164.A O no hydrogen 3.756 N/A CYS 166.A SG THR 175.A OG1 no hydrogen 3.467 N/A TYR 167.A N GLN 171.A OE1 no hydrogen 2.844 N/A TYR 167.A OH ASN 109.A OD1 no hydrogen 2.839 N/A ILE 169.A N ASP 168.A OD1 no hydrogen 2.896 N/A GLN 171.A N ASP 168.A O no hydrogen 3.113 N/A ILE 172.A N ASP 168.A O no hydrogen 3.345 N/A TYR 173.A N ILE 169.A O no hydrogen 3.058 N/A ASN 174.A N GLY 170.A O no hydrogen 2.740 N/A THR 175.A N GLN 171.A O no hydrogen 2.857 N/A THR 175.A OG1 GLN 171.A O no hydrogen 2.795 N/A ALA 176.A N ILE 172.A O no hydrogen 2.849 N/A PHE 177.A N TYR 173.A O no hydrogen 2.956 N/A HIS 179.A N ALA 176.A O no hydrogen 2.940 N/A GLU 180.A N PHE 177.A O no hydrogen 2.817 N/A GLY 181.A N PHE 178.A O no hydrogen 2.979 N/A LEU 187.A N ASN 220.A O no hydrogen 2.747 N/A ARG 188.A NH1 THR 222.A OG1 no hydrogen 2.921 N/A ARG 188.A NH1 ASP 243.A OD2 no hydrogen 2.873 N/A ARG 188.A NH2 ASP 243.A OD2 no hydrogen 2.900 N/A LEU 189.A N THR 222.A O no hydrogen 2.940 N/A GLN 190.A N LEU 164.A O no hydrogen 2.993 N/A GLN 190.A NE2 GLU 165.A OE1 no hydrogen 2.910 N/A PHE 191.A N SER 224.A O no hydrogen 2.873 N/A ILE 192.A N CYS 166.A O no hydrogen 2.878 N/A HIS 193.A N VAL 226.A O no hydrogen 2.903 N/A HIS 193.A ND1 GLY 200.A O no hydrogen 2.739 N/A GLY 194.A N ILE 199.A O no hydrogen 2.921 N/A GLY 198.A N ILE 195.A O no hydrogen 2.837 N/A ILE 199.A N TYR 167.A O no hydrogen 2.785 N/A ALA 202.A N ASP 205.A OD2 no hydrogen 3.167 N/A GLU 204.A N GLU 204.A OE1 no hydrogen 2.612 N/A ASP 205.A N ALA 202.A O no hydrogen 2.851 N/A VAL 206.A N ALA 202.A O no hydrogen 3.149 N/A LEU 207.A N VAL 203.A O no hydrogen 3.138 N/A PHE 208.A N GLU 204.A O no hydrogen 3.075 N/A LYS 209.A NZ ASP 213.A OD2 no hydrogen 2.905 N/A GLN 210.A N LEU 207.A O no hydrogen 2.831 N/A THR 211.A N PHE 208.A O no hydrogen 3.002 N/A THR 211.A OG1 PHE 208.A O no hydrogen 2.625 N/A ASP 213.A N LYS 209.A O no hydrogen 3.052 N/A ARG 214.A N GLN 210.A O no hydrogen 2.916 N/A ARG 214.A NH1 TYR 173.A OH no hydrogen 2.810 N/A LEU 215.A N THR 211.A O no hydrogen 2.826 N/A ILE 216.A N ALA 212.A O no hydrogen 2.860 N/A GLY 217.A N ALA 212.A O no hydrogen 3.293 N/A ASN 220.A N GLY 217.A O no hydrogen 2.945 N/A TYR 221.A OH ASP 213.A OD1 no hydrogen 2.566 N/A THR 222.A N LEU 187.A O no hydrogen 2.873 N/A SER 224.A N LEU 189.A O no hydrogen 2.952 N/A SER 224.A OG GLN 190.A OE1 no hydrogen 2.936 N/A VAL 226.A N PHE 191.A O no hydrogen 2.777 N/A ALA 228.A N HIS 193.A O no hydrogen 3.020 N/A GLY 229.A N ASP 250.A O no hydrogen 2.964 N/A PHE 231.A N ALA 228.A O no hydrogen 3.036 N/A GLN 232.A N GLY 229.A O no hydrogen 3.083 N/A LEU 234.A N PHE 231.A O no hydrogen 3.087 N/A GLY 235.A N GLN 232.A O no hydrogen 3.020 N/A LEU 237.A N PRO 233.A O no hydrogen 2.873 N/A ALA 238.A N LEU 234.A O no hydrogen 2.949 N/A VAL 239.A N GLY 235.A O no hydrogen 3.095 N/A ILE 240.A N THR 236.A O no hydrogen 2.936 N/A GLY 242.A N ALA 238.A O no hydrogen 2.606 N/A ASP 243.A N TRP 223.A O no hydrogen 2.864 N/A VAL 244.A N ILE 5.A O no hydrogen 3.091 N/A ARG 245.A N LEU 225.A O no hydrogen 3.014 N/A ARG 245.A NE ASP 250.A OD2 no hydrogen 2.842 N/A ARG 245.A NH2 ASP 250.A OD1 no hydrogen 2.803 N/A ARG 245.A NH2 ASP 250.A OD2 no hydrogen 3.432 N/A VAL 246.A N THR 7.A O no hydrogen 2.846 N/A LEU 248.A N ASN 263.A OD1 no hydrogen 2.933 N/A GLU 249.A N ALA 9.A O no hydrogen 3.075 N/A ASP 250.A N GLY 247.A O no hydrogen 2.965 N/A SER 251.A N GLY 247.A O no hydrogen 3.103 N/A SER 251.A OG GLY 229.A O no hydrogen 3.513 N/A SER 251.A OG TYR 253.A O no hydrogen 3.521 N/A TYR 253.A N SER 251.A OG no hydrogen 3.176 N/A ILE 254.A N LYS 258.A O no hydrogen 2.922 N/A LYS 258.A N GLU 255.A O no hydrogen 2.814 N/A ALA 260.A N LEU 252.A O no hydrogen 2.752 N/A LYS 261.A N GLU 265.A OE1 no hydrogen 2.739 N/A ASN 263.A N GLU 32.A OE1 no hydrogen 2.753 N/A ASN 263.A ND2 ILE 10.A O no hydrogen 2.999 N/A ASN 263.A ND2 GLU 32.A OE1 no hydrogen 2.917 N/A GLU 265.A N SER 262.A O no hydrogen 3.256 N/A GLU 265.A N SER 262.A OG no hydrogen 3.182 N/A GLN 266.A NE2 SER 251.A O no hydrogen 2.893 N/A GLN 266.A NE2 TYR 253.A O no hydrogen 2.913 N/A VAL 267.A N ASN 263.A O no hydrogen 3.039 N/A GLU 268.A N ALA 264.A O no hydrogen 2.771 N/A LYS 269.A N.A GLU 265.A O no hydrogen 3.170 N/A LYS 269.A N.B GLU 265.A O no hydrogen 3.156 N/A ARG 271.A N GLU 268.A O no hydrogen 2.898 N/A ILE 272.A N LYS 269.A O.A no hydrogen 3.086 N/A ILE 272.A N LYS 269.A O.B no hydrogen 3.088 N/A LYS 274.A N VAL 270.A O no hydrogen 3.007 N/A GLU 275.A N ARG 271.A O no hydrogen 3.127 N/A LEU 276.A N ILE 272.A O no hydrogen 3.035 N/A GLY 277.A N LYS 274.A O no hydrogen 3.046 N/A LYS 278.A N VAL 273.A O no hydrogen 3.018 N/A ARG 279.A N ASP 2.A O.A no hydrogen 2.824 N/A ARG 279.A N ASP 2.A O.B no hydrogen 2.802 N/A ARG 279.A NH1 PRO 280.A O no hydrogen 3.166 N/A ARG 279.A NH1 GLU 285.A OE1 no hydrogen 2.851 N/A ARG 279.A NH1 GLU 285.A OE2 no hydrogen 3.251 N/A ARG 279.A NH2 GLU 285.A OE2 no hydrogen 2.788 N/A ALA 281.A N VAL 4.A O no hydrogen 2.813 N/A THR 282.A N GLU 285.A OE1 no hydrogen 2.884 N/A GLU 285.A N THR 282.A OG1 no hydrogen 3.051 N/A VAL 286.A N THR 282.A O no hydrogen 2.902 N/A ARG 287.A N PRO 283.A O no hydrogen 3.030 N/A ARG 287.A NE GLU 104.A OE1 no hydrogen 2.786 N/A ARG 287.A NE GLU 104.A OE2 no hydrogen 3.103 N/A ARG 287.A NH1 ASP 74.A O no hydrogen 2.951 N/A ARG 287.A NH1 ASP 284.A OD1 no hydrogen 2.984 N/A ARG 287.A NH2 ASP 74.A O no hydrogen 2.914 N/A ARG 287.A NH2 GLU 104.A OE2 no hydrogen 2.866 N/A GLU 288.A N ASP 284.A O no hydrogen 3.051 N/A ILE 289.A N GLU 285.A O no hydrogen 2.733 N/A LEU 290.A N VAL 286.A O no hydrogen 2.902 N/A LEU 292.A N ARG 287.A O no hydrogen 2.897 N/A LYS 293.A NZ LYS 102.A O no hydrogen 2.881 N/A LYS 293.A NZ ASN 158.A O no hydrogen 2.925 N/A LYS 293.A NZ ASP 159.A O no hydrogen 3.361 N/A LYS 293.A NZ ARG 297.A O no hydrogen 3.475 N/A GLY 294.A N GLU 104.A OE1 no hydrogen 2.874 N/A ARG 297.A N GLY 294.A O no hydrogen 3.162 N/A ARG 297.A NH1 ASP 159.A OD2 no hydrogen 2.646 N/A ARG 297.A NH2 ASP 159.A OD2 no hydrogen 2.741 N/A ASN 299.A N LEU 101.A O no hydrogen 2.793 N/A ASN 299.A ND2 ALA 100.A O no hydrogen 2.841 N/A