Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3lt0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N ASN 115.A OD1 no hydrogen 3.122 N/A CYS 5.A N LYS 30.A O no hydrogen 2.922 N/A CYS 5.A SG PHE 6.A O no hydrogen 3.792 N/A PHE 6.A N MET 116.A O no hydrogen 3.133 N/A ILE 7.A N ILE 32.A O no hydrogen 2.806 N/A ALA 8.A N VAL 118.A O no hydrogen 2.852 N/A GLY 9.A N GLY 34.A O no hydrogen 2.980 N/A ILE 10.A N GLY 34.A O no hydrogen 3.444 N/A THR 13.A OG1 ASP 55.A OD2 no hydrogen 3.048 N/A ASN 14.A N ASP 12.A OD2 no hydrogen 2.885 N/A TYR 16.A OH GLY 218.A O no hydrogen 2.643 N/A TRP 18.A NE1 ASP 55.A O no hydrogen 3.204 N/A ILE 20.A N TYR 16.A O no hydrogen 2.976 N/A ALA 21.A N GLY 17.A O no hydrogen 2.974 N/A LYS 22.A N TRP 18.A O no hydrogen 2.912 N/A LYS 22.A NZ ASP 55.A O no hydrogen 3.193 N/A GLU 23.A N GLY 19.A O no hydrogen 3.148 N/A LEU 24.A N ILE 20.A O no hydrogen 2.974 N/A SER 25.A N ALA 21.A O no hydrogen 2.937 N/A LYS 26.A N LYS 22.A O no hydrogen 3.252 N/A LYS 26.A NZ GLU 23.A OE1 no hydrogen 3.070 N/A ARG 27.A N LEU 24.A O no hydrogen 2.906 N/A ARG 27.A NH1 GLU 23.A O no hydrogen 2.524 N/A ARG 27.A NH1 GLU 23.A OE2 no hydrogen 2.727 N/A ASN 28.A N SER 25.A O no hydrogen 2.918 N/A VAL 29.A N LEU 24.A O no hydrogen 3.165 N/A LYS 30.A N ASP 3.A O no hydrogen 3.019 N/A ILE 32.A N CYS 5.A O no hydrogen 2.922 N/A PHE 33.A N ASP 68.A O no hydrogen 2.985 N/A GLY 34.A N ILE 7.A O no hydrogen 2.756 N/A ILE 35.A N LEU 70.A O no hydrogen 2.759 N/A VAL 39.A N TRP 36.A O no hydrogen 2.928 N/A TYR 40.A N PRO 37.A O no hydrogen 2.950 N/A PHE 43.A N VAL 39.A O no hydrogen 2.985 N/A MET 44.A N TYR 40.A O no hydrogen 2.927 N/A LYS 45.A N ASN 41.A O no hydrogen 2.978 N/A ASN 46.A N ILE 42.A O no hydrogen 2.863 N/A TYR 47.A N PHE 43.A O no hydrogen 2.837 N/A LYS 48.A N MET 44.A O no hydrogen 2.830 N/A ASN 49.A N LYS 45.A O no hydrogen 2.899 N/A GLY 50.A N TYR 47.A O no hydrogen 3.007 N/A LYS 51.A N ASN 46.A O no hydrogen 2.931 N/A ASP 53.A N GLY 50.A O no hydrogen 3.270 N/A MET 56.A N ASP 53.A O no hydrogen 3.189 N/A ILE 57.A N ASN 54.A O no hydrogen 3.447 N/A ILE 58.A N LYS 62.A O no hydrogen 2.845 N/A ASP 59.A N LYS 62.A O no hydrogen 3.277 N/A ASP 61.A N ASP 59.A OD2 no hydrogen 3.295 N/A MET 64.A N MET 56.A O no hydrogen 2.787 N/A ASN 65.A N SER 25.A OG no hydrogen 3.236 N/A LEU 67.A N ILE 31.A O no hydrogen 2.750 N/A MET 69.A N ASP 68.A OD1 no hydrogen 2.830 N/A LEU 70.A N PHE 33.A O no hydrogen 2.859 N/A PHE 72.A N ILE 35.A O no hydrogen 2.795 N/A ASP 73.A N TYR 98.A O no hydrogen 2.806 N/A SER 75.A N ASP 73.A OD1 no hydrogen 2.960 N/A SER 75.A OG ASP 73.A OD1 no hydrogen 2.813 N/A PHE 76.A N ASP 73.A O no hydrogen 3.333 N/A THR 78.A N ASP 81.A OD2 no hydrogen 2.886 N/A THR 78.A OG1 ASP 81.A OD2 no hydrogen 3.188 N/A ASP 81.A N THR 78.A O no hydrogen 2.839 N/A ILE 82.A N ALA 79.A O no hydrogen 3.360 N/A THR 86.A N ASP 83.A OD2 no hydrogen 3.195 N/A THR 86.A OG1 ASP 83.A OD1 no hydrogen 2.739 N/A THR 86.A OG1 ASP 83.A OD2 no hydrogen 3.257 N/A LYS 87.A N ASP 83.A O no hydrogen 3.116 N/A ASN 88.A N GLU 84.A O no hydrogen 2.911 N/A ASN 89.A N THR 86.A O no hydrogen 2.867 N/A ARG 91.A N ASN 89.A OD1 no hydrogen 2.899 N/A TYR 92.A OH ASP 73.A OD2 no hydrogen 2.545 N/A ASN 93.A N ASN 89.A O no hydrogen 2.924 N/A LEU 95.A N TYR 92.A O no hydrogen 2.923 N/A THR 99.A OG1 ASP 102.A OD2 no hydrogen 2.796 N/A ILE 100.A N PHE 76.A O no hydrogen 2.949 N/A GLU 101.A N ASP 77.A O no hydrogen 2.936 N/A VAL 103.A N THR 99.A O no hydrogen 2.884 N/A ALA 104.A N ILE 100.A O no hydrogen 3.129 N/A ASN 105.A N GLU 101.A O no hydrogen 2.967 N/A LEU 106.A N ASP 102.A O no hydrogen 2.927 N/A ILE 107.A N VAL 103.A O no hydrogen 2.942 N/A HIS 108.A N ALA 104.A O no hydrogen 3.032 N/A GLN 109.A N ASN 105.A O no hydrogen 2.905 N/A LYS 110.A N LEU 106.A O no hydrogen 3.015 N/A TYR 111.A N ILE 107.A O no hydrogen 2.791 N/A TYR 111.A OH ASP 68.A OD2 no hydrogen 2.607 N/A GLY 112.A N HIS 108.A O no hydrogen 2.810 N/A LYS 113.A NZ HIS 108.A NE2 no hydrogen 3.335 N/A ILE 114.A N ILE 160.A O no hydrogen 2.841 N/A ASN 115.A N ILE 4.A O no hydrogen 3.207 N/A ASN 115.A ND2 ASP 3.A OD1 no hydrogen 2.591 N/A MET 116.A N ILE 4.A O no hydrogen 3.172 N/A LEU 117.A N SER 166.A O no hydrogen 3.124 N/A VAL 118.A N PHE 6.A O no hydrogen 2.829 N/A HIS 119.A N ILE 168.A O no hydrogen 2.827 N/A HIS 119.A NE2 SER 149.A OG no hydrogen 2.864 N/A SER 120.A N ALA 8.A O no hydrogen 2.822 N/A ASN 123.A N SER 146.A OG no hydrogen 2.906 N/A LYS 125.A N ASP 141.A OD2 no hydrogen 2.975 N/A VAL 127.A N ALA 124.A O no hydrogen 3.317 N/A LYS 129.A N GLU 126.A O no hydrogen 2.846 N/A ASN 133.A N ASP 130.A O.A no hydrogen 2.980 N/A ASN 133.A N ASP 130.A O.B no hydrogen 2.901 N/A ASN 133.A N ASP 130.A OD1.B no hydrogen 2.914 N/A THR 134.A N LEU 131.A O no hydrogen 3.063 N/A THR 134.A OG1 ASP 130.A O.A no hydrogen 2.872 N/A THR 134.A OG1 ASP 130.A O.B no hydrogen 3.039 N/A SER 135.A N GLU 126.A OE1 no hydrogen 2.784 N/A SER 135.A OG GLU 126.A OE1 no hydrogen 3.502 N/A SER 135.A OG GLU 126.A OE2 no hydrogen 2.577 N/A GLY 138.A N SER 135.A OG no hydrogen 2.987 N/A TYR 139.A N SER 135.A O no hydrogen 2.852 N/A LEU 140.A N ARG 136.A O no hydrogen 2.970 N/A ASP 141.A N LYS 137.A O no hydrogen 2.965 N/A ALA 142.A N GLY 138.A O no hydrogen 3.145 N/A LEU 143.A N TYR 139.A O no hydrogen 3.078 N/A SER 144.A N LEU 140.A O no hydrogen 2.750 N/A LYS 145.A N ASP 141.A O no hydrogen 2.880 N/A LYS 145.A NZ ASP 141.A OD1 no hydrogen 2.723 N/A SER 146.A N ALA 142.A O no hydrogen 2.855 N/A SER 146.A OG ASN 123.A O no hydrogen 2.849 N/A SER 146.A OG ALA 142.A O no hydrogen 3.082 N/A SER 147.A N LEU 143.A O no hydrogen 3.061 N/A SER 147.A OG ALA 189.A O no hydrogen 2.662 N/A TYR 148.A N LEU 143.A O no hydrogen 2.837 N/A SER 149.A N SER 144.A O no hydrogen 3.254 N/A SER 149.A OG HIS 119.A NE2 no hydrogen 2.864 N/A SER 149.A OG LYS 145.A O no hydrogen 2.622 N/A LEU 150.A N SER 147.A O no hydrogen 3.026 N/A SER 152.A N TYR 148.A O no hydrogen 2.986 N/A SER 152.A OG ASP 77.A OD1 no hydrogen 2.481 N/A LEU 153.A N SER 149.A O no hydrogen 2.955 N/A CYS 154.A N LEU 150.A O no hydrogen 2.994 N/A CYS 154.A SG LEU 150.A O no hydrogen 3.310 N/A LYS 155.A N ILE 151.A O no hydrogen 2.835 N/A LYS 155.A NZ TYR 156.A OH no hydrogen 3.424 N/A TYR 156.A N SER 152.A O no hydrogen 2.926 N/A PHE 157.A N LEU 153.A O no hydrogen 2.833 N/A VAL 158.A N CYS 154.A O no hydrogen 2.962 N/A ILE 160.A N PHE 157.A O no hydrogen 2.879 N/A MET 161.A N VAL 158.A O no hydrogen 3.197 N/A LYS 162.A N ILE 114.A O no hydrogen 3.027 N/A GLN 164.A N ASN 209.A O no hydrogen 3.254 N/A SER 165.A N LYS 162.A O no hydrogen 3.191 N/A SER 165.A OG LYS 162.A O no hydrogen 2.621 N/A SER 166.A N ASN 115.A O no hydrogen 3.198 N/A SER 166.A OG LEU 261.A O no hydrogen 2.708 N/A ILE 167.A N ARG 211.A O no hydrogen 2.913 N/A ILE 168.A N LEU 117.A O no hydrogen 2.942 N/A SER 169.A N ASN 213.A O no hydrogen 3.252 N/A SER 169.A OG THR 214.A OG1 no hydrogen 2.911 N/A THR 171.A N ILE 215.A O no hydrogen 2.816 N/A THR 171.A OG1 GLU 194.A OE2 no hydrogen 2.547 N/A TYR 172.A N THR 171.A OG1 no hydrogen 2.827 N/A HIS 173.A ND1 TYR 275.A OH no hydrogen 2.682 N/A SER 175.A N TYR 172.A O no hydrogen 3.211 N/A SER 175.A OG TYR 172.A O no hydrogen 3.224 N/A SER 175.A OG GLN 176.A OE1 no hydrogen 3.404 N/A SER 175.A OG GLU 194.A OE1 no hydrogen 3.207 N/A SER 175.A OG GLU 194.A OE2 no hydrogen 2.696 N/A GLN 176.A N HIS 173.A O no hydrogen 2.819 N/A LYS 177.A N HIS 173.A O no hydrogen 2.957 N/A TYR 182.A N VAL 179.A O no hydrogen 3.041 N/A GLY 183.A N GLY 181.A O no hydrogen 2.965 N/A GLY 184.A N LYS 129.A O no hydrogen 2.881 N/A MET 186.A N GLY 183.A O no hydrogen 3.087 N/A ALA 189.A N GLY 185.A O no hydrogen 2.794 N/A LYS 190.A N MET 186.A O no hydrogen 3.011 N/A LYS 190.A NZ LEU 170.A O no hydrogen 2.914 N/A ALA 191.A N SER 187.A O no hydrogen 3.024 N/A ALA 192.A N SER 188.A O no hydrogen 3.001 N/A LEU 193.A N ALA 189.A O no hydrogen 2.884 N/A GLU 194.A N LYS 190.A O no hydrogen 3.036 N/A SER 195.A N ALA 191.A O no hydrogen 3.110 N/A ASP 196.A N ALA 192.A O no hydrogen 2.782 N/A THR 197.A N LEU 193.A O no hydrogen 2.874 N/A THR 197.A OG1 LEU 193.A O no hydrogen 2.817 N/A VAL 199.A N SER 195.A O no hydrogen 3.139 N/A LEU 200.A N ASP 196.A O no hydrogen 2.747 N/A ALA 201.A N THR 197.A O no hydrogen 2.963 N/A TYR 202.A N ARG 198.A O no hydrogen 3.152 N/A HIS 203.A N VAL 199.A O no hydrogen 3.088 N/A LEU 204.A N LEU 200.A O no hydrogen 2.704 N/A GLY 205.A N ALA 201.A O no hydrogen 2.874 N/A ARG 206.A N TYR 202.A O no hydrogen 3.071 N/A ASN 207.A N HIS 203.A O no hydrogen 3.030 N/A TYR 208.A N LEU 204.A O no hydrogen 2.972 N/A ASN 209.A N GLY 205.A O no hydrogen 3.102 N/A ILE 210.A N LEU 204.A O no hydrogen 3.002 N/A ARG 211.A N SER 165.A O no hydrogen 3.068 N/A ARG 211.A NH1 LEU 261.A O no hydrogen 3.254 N/A ARG 211.A NH1 ILE 269.A O no hydrogen 3.075 N/A ARG 211.A NH2 LEU 261.A O no hydrogen 3.132 N/A ILE 212.A N THR 270.A OG1 no hydrogen 3.183 N/A ASN 213.A N ILE 167.A O no hydrogen 3.033 N/A ASN 213.A ND2 ILE 269.A O no hydrogen 3.116 N/A THR 214.A N GLN 272.A O no hydrogen 2.859 N/A THR 214.A OG1 SER 169.A O no hydrogen 3.216 N/A THR 214.A OG1 SER 169.A OG no hydrogen 2.911 N/A ILE 215.A N SER 169.A O no hydrogen 2.908 N/A SER 216.A N ILE 274.A O no hydrogen 2.729 N/A ALA 217.A N THR 171.A O no hydrogen 3.253 N/A GLY 218.A N VAL 276.A O no hydrogen 3.122 N/A LYS 221.A NZ ASP 233.A OD1 no hydrogen 2.718 N/A SER 222.A N LEU 220.A O no hydrogen 2.787 N/A ALA 225.A N SER 222.A OG no hydrogen 3.245 N/A THR 226.A N SER 222.A O no hydrogen 3.339 N/A THR 226.A N ARG 223.A O no hydrogen 3.064 N/A ALA 227.A N ALA 224.A O no hydrogen 2.813 N/A ILE 228.A N ALA 225.A O no hydrogen 3.187 N/A TYR 234.A N THR 230.A O no hydrogen 2.866 N/A ALA 235.A N PHE 231.A O no hydrogen 3.031 N/A ILE 236.A N ILE 232.A O no hydrogen 2.984 N/A GLU 237.A N ASP 233.A O no hydrogen 3.030 N/A TYR 238.A N TYR 234.A O no hydrogen 2.885 N/A SER 239.A N ALA 235.A O no hydrogen 2.961 N/A GLU 240.A N ILE 236.A O no hydrogen 2.861 N/A LYS 241.A N GLU 237.A O no hydrogen 3.078 N/A LYS 241.A N TYR 238.A O no hydrogen 3.152 N/A LYS 241.A NZ TYR 242.A OH no hydrogen 3.449 N/A TYR 242.A N TYR 238.A O no hydrogen 2.842 N/A ALA 243.A N SER 239.A O no hydrogen 2.964 N/A LEU 245.A N ASN 278.A O no hydrogen 3.270 N/A ARG 246.A NE LYS 241.A O no hydrogen 3.251 N/A GLN 247.A NE2 ASN 278.A OD1 no hydrogen 3.351 N/A LEU 250.A N ASP 253.A OD2 no hydrogen 2.935 N/A ASP 253.A N LEU 250.A O no hydrogen 2.932 N/A GLY 255.A N SER 251.A O no hydrogen 2.902 N/A SER 256.A N THR 252.A O no hydrogen 2.884 N/A SER 256.A OG THR 252.A O no hydrogen 3.306 N/A SER 256.A OG ASP 253.A O no hydrogen 3.200 N/A ALA 258.A N ILE 254.A O no hydrogen 2.857 N/A SER 259.A N GLY 255.A O no hydrogen 2.888 N/A PHE 260.A N SER 256.A O no hydrogen 3.172 N/A LEU 261.A N VAL 257.A O no hydrogen 2.922 N/A LEU 262.A N ALA 258.A O no hydrogen 2.869 N/A SER 263.A N PHE 260.A O no hydrogen 3.029 N/A SER 263.A OG PHE 260.A O no hydrogen 2.794 N/A GLU 265.A N SER 263.A OG no hydrogen 3.180 N/A SER 266.A N SER 263.A O no hydrogen 3.412 N/A SER 266.A OG PHE 260.A O no hydrogen 2.984 N/A SER 266.A OG LEU 261.A O no hydrogen 3.084 N/A SER 266.A OG SER 263.A O no hydrogen 3.175 N/A ARG 267.A N ARG 264.A O no hydrogen 3.074 N/A ILE 269.A N SER 266.A O no hydrogen 2.943 N/A THR 270.A OG1 ILE 212.A O no hydrogen 3.450 N/A GLY 271.A N ILE 212.A O no hydrogen 2.703 N/A GLN 272.A N ASN 213.A OD1 no hydrogen 3.001 N/A GLN 272.A NE2 THR 270.A O no hydrogen 3.051 N/A ILE 274.A N THR 214.A O no hydrogen 2.850 N/A TYR 275.A OH HIS 173.A ND1 no hydrogen 2.682 N/A VAL 276.A N SER 216.A O no hydrogen 2.871 N/A GLY 279.A N ASP 277.A OD1 no hydrogen 2.892 N/A LEU 280.A N ASP 277.A O no hydrogen 3.199 N/A ASN 281.A N ASP 277.A OD2 no hydrogen 2.951 N/A ASN 281.A ND2 ASP 277.A OD1 no hydrogen 3.116 N/A ASN 281.A ND2 ASP 277.A OD2 no hydrogen 2.815 N/A ILE 282.A N GLY 279.A O no hydrogen 3.070 N/A MET 283.A N LEU 280.A O no hydrogen 3.168 N/A ASP 287.A N ASP 287.A OD1 no hydrogen 2.636 N/A