Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3lt4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N ASN 114.A OD1 no hydrogen 3.144 N/A CYS 4.A N LYS 29.A O no hydrogen 2.785 N/A CYS 4.A SG PHE 5.A O no hydrogen 3.792 N/A PHE 5.A N MET 115.A O no hydrogen 3.101 N/A ILE 6.A N ILE 31.A O no hydrogen 2.787 N/A ALA 7.A N VAL 117.A O no hydrogen 2.908 N/A GLY 8.A N GLY 33.A O no hydrogen 2.936 N/A ILE 9.A N GLY 33.A O no hydrogen 3.353 N/A THR 12.A OG1 ASP 54.A OD2 no hydrogen 2.897 N/A ASN 13.A N ASP 11.A OD2 no hydrogen 2.625 N/A TYR 15.A OH GLY 217.A O no hydrogen 2.643 N/A TRP 17.A NE1 ASP 54.A O no hydrogen 3.112 N/A ILE 19.A N TYR 15.A O no hydrogen 2.937 N/A ALA 20.A N GLY 16.A O no hydrogen 2.838 N/A LYS 21.A N TRP 17.A O no hydrogen 2.805 N/A LYS 21.A NZ ASP 54.A O no hydrogen 3.083 N/A LYS 21.A NZ ILE 56.A O no hydrogen 3.409 N/A GLU 22.A N GLY 18.A O no hydrogen 3.153 N/A LEU 23.A N ILE 19.A O no hydrogen 2.977 N/A SER 24.A N ALA 20.A O no hydrogen 2.975 N/A LYS 25.A N LYS 21.A O no hydrogen 3.175 N/A LYS 25.A NZ GLU 22.A OE1 no hydrogen 3.227 N/A ARG 26.A N LEU 23.A O no hydrogen 2.999 N/A ARG 26.A NE.B SER 258.A OG no hydrogen 2.703 N/A ARG 26.A NH1.A GLU 22.A O no hydrogen 2.476 N/A ARG 26.A NH1.A GLU 22.A OE2 no hydrogen 2.629 N/A ARG 26.A NH2.A GLU 22.A OE2 no hydrogen 3.479 N/A ASN 27.A N SER 24.A O no hydrogen 2.919 N/A VAL 28.A N LEU 23.A O no hydrogen 3.121 N/A LYS 29.A N ASP 2.A O no hydrogen 2.850 N/A ILE 31.A N CYS 4.A O no hydrogen 2.862 N/A PHE 32.A N ASP 67.A O no hydrogen 2.952 N/A GLY 33.A N ILE 6.A O no hydrogen 2.728 N/A ILE 34.A N LEU 69.A O no hydrogen 2.803 N/A VAL 38.A N TRP 35.A O no hydrogen 2.941 N/A TYR 39.A N PRO 36.A O no hydrogen 2.895 N/A PHE 42.A N VAL 38.A O no hydrogen 2.955 N/A MET 43.A N TYR 39.A O no hydrogen 2.929 N/A LYS 44.A N ASN 40.A O no hydrogen 2.949 N/A ASN 45.A N ILE 41.A O no hydrogen 2.937 N/A TYR 46.A N PHE 42.A O no hydrogen 2.847 N/A LYS 47.A N MET 43.A O no hydrogen 2.848 N/A ASN 48.A N LYS 44.A O no hydrogen 2.849 N/A GLY 49.A N TYR 46.A O no hydrogen 3.018 N/A LYS 50.A N ASN 45.A O no hydrogen 2.935 N/A ASP 52.A N GLY 49.A O no hydrogen 3.268 N/A MET 55.A N ASP 52.A O no hydrogen 3.090 N/A ILE 56.A N ASN 53.A O no hydrogen 3.293 N/A ILE 57.A N LYS 61.A O no hydrogen 2.968 N/A ASP 58.A N LYS 61.A O no hydrogen 3.201 N/A ASP 60.A N ASP 58.A OD2 no hydrogen 3.503 N/A MET 63.A N MET 55.A O no hydrogen 2.750 N/A ASN 64.A N SER 24.A OG no hydrogen 3.300 N/A LEU 66.A N ILE 30.A O no hydrogen 2.823 N/A MET 68.A N ASP 67.A OD1 no hydrogen 2.836 N/A LEU 69.A N PHE 32.A O no hydrogen 2.913 N/A PHE 71.A N ILE 34.A O no hydrogen 2.767 N/A ASP 72.A N TYR 97.A O no hydrogen 2.810 N/A SER 74.A N ASP 72.A OD1 no hydrogen 2.904 N/A SER 74.A OG ASP 72.A OD1 no hydrogen 2.886 N/A PHE 75.A N ASP 72.A O no hydrogen 3.409 N/A THR 77.A N ASP 80.A OD2 no hydrogen 2.967 N/A THR 77.A OG1 ASP 80.A OD2 no hydrogen 3.049 N/A ASP 80.A N THR 77.A O no hydrogen 2.918 N/A ILE 81.A N ALA 78.A O no hydrogen 3.325 N/A THR 85.A N ASP 82.A OD2 no hydrogen 2.982 N/A THR 85.A OG1 ASP 82.A OD1 no hydrogen 2.591 N/A THR 85.A OG1 ASP 82.A OD2 no hydrogen 3.141 N/A LYS 86.A N ASP 82.A O no hydrogen 3.052 N/A LYS 86.A NZ GLU 83.A OE2 no hydrogen 3.253 N/A ASN 87.A N GLU 83.A O no hydrogen 2.642 N/A ASN 88.A N THR 85.A O no hydrogen 2.951 N/A ARG 90.A N ASN 88.A OD1 no hydrogen 2.810 N/A TYR 91.A OH ASP 72.A OD2 no hydrogen 2.611 N/A ASN 92.A N ASN 88.A O no hydrogen 2.908 N/A LEU 94.A N TYR 91.A O no hydrogen 2.840 N/A THR 98.A OG1 ASP 101.A OD2 no hydrogen 2.738 N/A ILE 99.A N PHE 75.A O no hydrogen 2.964 N/A GLU 100.A N ASP 76.A O no hydrogen 2.896 N/A VAL 102.A N THR 98.A O no hydrogen 2.927 N/A ALA 103.A N ILE 99.A O no hydrogen 3.162 N/A ASN 104.A N GLU 100.A O no hydrogen 2.971 N/A LEU 105.A N ASP 101.A O no hydrogen 2.924 N/A ILE 106.A N VAL 102.A O no hydrogen 2.880 N/A HIS 107.A N ALA 103.A O no hydrogen 2.975 N/A GLN 108.A N ASN 104.A O no hydrogen 2.864 N/A LYS 109.A N LEU 105.A O no hydrogen 2.953 N/A TYR 110.A N ILE 106.A O no hydrogen 2.867 N/A TYR 110.A OH ASP 67.A OD2 no hydrogen 2.588 N/A GLY 111.A N HIS 107.A O no hydrogen 2.828 N/A LYS 112.A NZ HIS 107.A NE2 no hydrogen 3.250 N/A ILE 113.A N ILE 159.A O no hydrogen 2.839 N/A ASN 114.A N ILE 3.A O no hydrogen 3.210 N/A ASN 114.A ND2 ASP 2.A OD1 no hydrogen 2.582 N/A MET 115.A N ILE 3.A O no hydrogen 3.098 N/A LEU 116.A N SER 165.A O no hydrogen 3.079 N/A VAL 117.A N PHE 5.A O no hydrogen 2.921 N/A HIS 118.A N ILE 167.A O no hydrogen 2.831 N/A HIS 118.A NE2 SER 148.A OG no hydrogen 2.839 N/A SER 119.A N ALA 7.A O no hydrogen 2.862 N/A ASN 122.A N SER 145.A OG no hydrogen 2.990 N/A LYS 124.A N ASP 140.A OD2 no hydrogen 2.851 N/A LYS 124.A NZ GLU 125.A OE2 no hydrogen 3.060 N/A VAL 126.A N ALA 123.A O no hydrogen 3.280 N/A LYS 128.A N GLU 125.A O no hydrogen 2.891 N/A ASN 132.A N ASP 129.A O no hydrogen 2.896 N/A ASN 132.A N ASP 129.A OD2.A no hydrogen 3.167 N/A THR 133.A N LEU 130.A O no hydrogen 3.025 N/A THR 133.A OG1 ASP 129.A O no hydrogen 3.054 N/A SER 134.A N GLU 125.A OE1 no hydrogen 2.786 N/A SER 134.A OG GLU 125.A OE1 no hydrogen 3.435 N/A SER 134.A OG GLU 125.A OE2 no hydrogen 2.552 N/A GLY 137.A N SER 134.A OG no hydrogen 3.144 N/A TYR 138.A N SER 134.A O no hydrogen 2.865 N/A LEU 139.A N ARG 135.A O no hydrogen 2.934 N/A ASP 140.A N LYS 136.A O no hydrogen 2.916 N/A ALA 141.A N GLY 137.A O no hydrogen 3.157 N/A LEU 142.A N TYR 138.A O no hydrogen 3.136 N/A SER 143.A N LEU 139.A O no hydrogen 2.755 N/A LYS 144.A N ASP 140.A O no hydrogen 2.882 N/A LYS 144.A NZ ASP 140.A OD1 no hydrogen 2.674 N/A SER 145.A N ALA 141.A O no hydrogen 2.881 N/A SER 145.A OG ASN 122.A O no hydrogen 2.760 N/A SER 145.A OG ALA 141.A O no hydrogen 3.002 N/A SER 146.A N LEU 142.A O no hydrogen 3.007 N/A SER 146.A OG ALA 188.A O no hydrogen 2.668 N/A TYR 147.A N LEU 142.A O no hydrogen 2.808 N/A SER 148.A N SER 143.A O no hydrogen 3.284 N/A SER 148.A OG HIS 118.A NE2 no hydrogen 2.839 N/A SER 148.A OG LYS 144.A O no hydrogen 2.584 N/A LEU 149.A N SER 146.A O no hydrogen 3.031 N/A SER 151.A N TYR 147.A O no hydrogen 2.924 N/A SER 151.A OG ASP 76.A OD1 no hydrogen 2.481 N/A LEU 152.A N SER 148.A O no hydrogen 2.943 N/A CYS 153.A N LEU 149.A O no hydrogen 2.876 N/A CYS 153.A SG LEU 149.A O no hydrogen 3.406 N/A LYS 154.A N ILE 150.A O no hydrogen 2.850 N/A TYR 155.A N SER 151.A O no hydrogen 2.975 N/A PHE 156.A N LEU 152.A O no hydrogen 2.922 N/A VAL 157.A N CYS 153.A O no hydrogen 3.043 N/A ILE 159.A N PHE 156.A O no hydrogen 2.860 N/A MET 160.A N VAL 157.A O no hydrogen 3.051 N/A LYS 161.A N ILE 113.A O no hydrogen 3.128 N/A GLN 163.A N ASN 208.A O no hydrogen 3.160 N/A SER 164.A N LYS 161.A O no hydrogen 3.147 N/A SER 164.A OG LYS 161.A O no hydrogen 2.669 N/A SER 165.A N ASN 114.A O no hydrogen 3.260 N/A SER 165.A OG LEU 260.A O no hydrogen 2.678 N/A ILE 166.A N ARG 210.A O no hydrogen 2.903 N/A ILE 167.A N LEU 116.A O no hydrogen 2.923 N/A SER 168.A N ASN 212.A O no hydrogen 3.220 N/A SER 168.A OG THR 213.A OG1 no hydrogen 2.820 N/A THR 170.A N ILE 214.A O no hydrogen 2.798 N/A THR 170.A OG1 GLU 193.A OE2 no hydrogen 2.577 N/A TYR 171.A N THR 170.A OG1 no hydrogen 2.706 N/A HIS 172.A ND1 TYR 274.A OH no hydrogen 2.539 N/A SER 174.A N TYR 171.A O no hydrogen 3.110 N/A SER 174.A OG TYR 171.A O no hydrogen 3.158 N/A SER 174.A OG GLN 175.A OE1 no hydrogen 3.317 N/A SER 174.A OG GLU 193.A OE1 no hydrogen 3.227 N/A SER 174.A OG GLU 193.A OE2 no hydrogen 2.685 N/A GLN 175.A N HIS 172.A O no hydrogen 2.831 N/A LYS 176.A N HIS 172.A O no hydrogen 2.982 N/A TYR 181.A N VAL 178.A O no hydrogen 3.057 N/A GLY 183.A N LYS 128.A O no hydrogen 2.933 N/A MET 185.A N GLY 182.A O no hydrogen 3.197 N/A SER 187.A OG GLY 184.A O no hydrogen 3.528 N/A ALA 188.A N GLY 184.A O no hydrogen 2.811 N/A LYS 189.A N MET 185.A O no hydrogen 2.992 N/A LYS 189.A NZ LEU 169.A O no hydrogen 2.806 N/A ALA 190.A N SER 186.A O no hydrogen 3.006 N/A ALA 191.A N SER 187.A O no hydrogen 2.941 N/A LEU 192.A N ALA 188.A O no hydrogen 2.837 N/A GLU 193.A N LYS 189.A O no hydrogen 3.003 N/A SER 194.A N ALA 190.A O no hydrogen 3.141 N/A ASP 195.A N ALA 191.A O no hydrogen 2.741 N/A THR 196.A N LEU 192.A O no hydrogen 2.990 N/A THR 196.A OG1 LEU 192.A O no hydrogen 2.774 N/A ARG 197.A N SER 194.A O no hydrogen 3.014 N/A VAL 198.A N SER 194.A O no hydrogen 3.259 N/A LEU 199.A N ASP 195.A O no hydrogen 2.753 N/A ALA 200.A N THR 196.A O no hydrogen 2.922 N/A TYR 201.A N ARG 197.A O no hydrogen 3.062 N/A HIS 202.A N VAL 198.A O no hydrogen 3.153 N/A LEU 203.A N LEU 199.A O no hydrogen 2.745 N/A GLY 204.A N ALA 200.A O no hydrogen 2.904 N/A ARG 205.A N TYR 201.A O no hydrogen 2.954 N/A ASN 206.A N HIS 202.A O no hydrogen 2.873 N/A TYR 207.A N LEU 203.A O no hydrogen 2.934 N/A ASN 208.A N GLY 204.A O no hydrogen 3.012 N/A ILE 209.A N LEU 203.A O no hydrogen 2.949 N/A ARG 210.A N SER 164.A O no hydrogen 3.111 N/A ARG 210.A NH1 LEU 260.A O no hydrogen 3.362 N/A ARG 210.A NH1 ILE 268.A O no hydrogen 2.973 N/A ARG 210.A NH2 LEU 260.A O no hydrogen 3.113 N/A ILE 211.A N THR 269.A OG1 no hydrogen 3.046 N/A ASN 212.A N ILE 166.A O no hydrogen 2.980 N/A ASN 212.A ND2 ILE 268.A O no hydrogen 3.037 N/A THR 213.A N GLN 271.A O no hydrogen 2.851 N/A THR 213.A OG1 SER 168.A O no hydrogen 3.099 N/A THR 213.A OG1 SER 168.A OG no hydrogen 2.820 N/A ILE 214.A N SER 168.A O no hydrogen 2.876 N/A SER 215.A N ILE 273.A O no hydrogen 2.721 N/A ALA 216.A N THR 170.A O no hydrogen 3.264 N/A GLY 217.A N VAL 275.A O no hydrogen 3.100 N/A LYS 220.A NZ ASP 232.A OD1 no hydrogen 2.847 N/A SER 221.A N LEU 219.A O no hydrogen 2.802 N/A ALA 224.A N SER 221.A OG no hydrogen 3.083 N/A THR 225.A N SER 221.A O no hydrogen 3.144 N/A THR 225.A OG1 SER 221.A O no hydrogen 3.344 N/A ALA 226.A N ARG 222.A O no hydrogen 3.367 N/A ALA 226.A N ALA 223.A O no hydrogen 3.015 N/A ILE 227.A N ALA 224.A O no hydrogen 3.084 N/A TYR 233.A N THR 229.A O no hydrogen 2.962 N/A ALA 234.A N PHE 230.A O no hydrogen 3.047 N/A ILE 235.A N ILE 231.A O no hydrogen 2.984 N/A GLU 236.A N ASP 232.A O no hydrogen 2.963 N/A TYR 237.A N TYR 233.A O no hydrogen 2.761 N/A SER 238.A N ALA 234.A O no hydrogen 2.866 N/A GLU 239.A N ILE 235.A O no hydrogen 2.884 N/A LYS 240.A N GLU 236.A O no hydrogen 3.031 N/A LYS 240.A N TYR 237.A O no hydrogen 3.182 N/A LYS 240.A NZ TYR 241.A OH no hydrogen 3.554 N/A TYR 241.A N TYR 237.A O no hydrogen 2.816 N/A ALA 242.A N SER 238.A O no hydrogen 2.822 N/A LEU 244.A N ASN 277.A O no hydrogen 3.139 N/A ARG 245.A NH1 GLU 239.A O no hydrogen 3.053 N/A LEU 249.A N ASP 252.A OD2 no hydrogen 2.893 N/A ASP 252.A N LEU 249.A O no hydrogen 2.892 N/A GLY 254.A N SER 250.A O no hydrogen 2.892 N/A SER 255.A N THR 251.A O no hydrogen 2.920 N/A SER 255.A OG THR 251.A O no hydrogen 3.286 N/A SER 255.A OG ASP 252.A O no hydrogen 3.384 N/A ALA 257.A N ILE 253.A O no hydrogen 2.898 N/A SER 258.A N GLY 254.A O no hydrogen 2.836 N/A PHE 259.A N SER 255.A O no hydrogen 3.107 N/A LEU 260.A N VAL 256.A O no hydrogen 2.832 N/A LEU 261.A N ALA 257.A O no hydrogen 2.873 N/A SER 262.A N PHE 259.A O no hydrogen 3.068 N/A SER 262.A OG PHE 259.A O no hydrogen 2.881 N/A GLU 264.A N SER 262.A OG no hydrogen 3.163 N/A SER 265.A N SER 262.A O no hydrogen 3.499 N/A SER 265.A OG PHE 259.A O no hydrogen 3.037 N/A SER 265.A OG LEU 260.A O no hydrogen 3.086 N/A SER 265.A OG SER 262.A O no hydrogen 3.108 N/A ARG 266.A N ARG 263.A O no hydrogen 3.013 N/A ARG 266.A NE.B ARG 263.A O no hydrogen 2.700 N/A ILE 268.A N SER 265.A O no hydrogen 2.897 N/A THR 269.A OG1 ILE 211.A O no hydrogen 3.252 N/A GLY 270.A N ILE 211.A O no hydrogen 2.696 N/A GLN 271.A N ASN 212.A OD1 no hydrogen 3.019 N/A GLN 271.A NE2 THR 269.A O no hydrogen 2.988 N/A ILE 273.A N THR 213.A O no hydrogen 2.865 N/A TYR 274.A OH HIS 172.A ND1 no hydrogen 2.539 N/A VAL 275.A N SER 215.A O no hydrogen 2.868 N/A GLY 278.A N ASP 276.A OD1 no hydrogen 2.875 N/A LEU 279.A N ASP 276.A O no hydrogen 3.124 N/A ASN 280.A N ASP 276.A OD2 no hydrogen 2.931 N/A ASN 280.A ND2 ASP 276.A OD1 no hydrogen 3.136 N/A ASN 280.A ND2 ASP 276.A OD2 no hydrogen 2.762 N/A ILE 281.A N GLY 278.A O no hydrogen 3.013 N/A MET 282.A N LEU 279.A O no hydrogen 3.105 N/A