Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3lxl_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N VAL 76.A O no hydrogen 2.784 N/A GLU 5.A N TYR 28.A OH no hydrogen 2.974 N/A HIS 8.A N GLU 5.A O no hydrogen 3.031 N/A LEU 9.A N GLU 6.A O no hydrogen 3.174 N/A LYS 10.A N ARG 27.A O no hydrogen 2.778 N/A ILE 12.A N LEU 25.A O no hydrogen 2.856 N/A SER 13.A N LEU 25.A O no hydrogen 3.226 N/A GLN 14.A NE2 TYR 11.A OH no hydrogen 2.869 N/A GLN 14.A NE2 GLU 24.A OE2 no hydrogen 3.005 N/A LEU 15.A N VAL 23.A O no hydrogen 2.874 N/A GLY 16.A N VAL 23.A O no hydrogen 3.145 N/A GLY 18.A N GLY 21.A O no hydrogen 2.946 N/A GLY 21.A N GLY 18.A O no hydrogen 2.965 N/A SER 22.A N GLN 43.A O no hydrogen 2.921 N/A VAL 23.A N GLY 16.A O no hydrogen 2.860 N/A GLU 24.A N VAL 41.A O no hydrogen 2.823 N/A LEU 25.A N SER 13.A O no hydrogen 2.754 N/A CYS 26.A N VAL 39.A O no hydrogen 3.011 N/A ARG 27.A N LYS 10.A O no hydrogen 2.923 N/A ARG 27.A NH1 GLY 36.A O no hydrogen 2.949 N/A TYR 28.A N ALA 37.A O no hydrogen 2.889 N/A ASP 29.A N HIS 8.A O no hydrogen 2.795 N/A GLY 32.A N ASP 29.A O no hydrogen 2.933 N/A ASN 34.A N ASP 29.A OD1 no hydrogen 2.758 N/A THR 35.A N ASP 33.A OD1 no hydrogen 3.134 N/A THR 35.A OG1 ASP 33.A OD1 no hydrogen 2.552 N/A THR 35.A OG1 ASP 33.A OD2 no hydrogen 3.316 N/A GLY 36.A N ASP 29.A OD2 no hydrogen 2.904 N/A VAL 39.A N CYS 26.A O no hydrogen 2.881 N/A ALA 40.A N MET 89.A O no hydrogen 2.968 N/A VAL 41.A N GLU 24.A O no hydrogen 2.858 N/A LYS 42.A N LEU 87.A O no hydrogen 2.813 N/A LYS 42.A NZ GLU 58.A OE1 no hydrogen 2.759 N/A GLN 43.A N SER 22.A O no hydrogen 3.089 N/A GLN 43.A NE2 SER 22.A O no hydrogen 3.094 N/A GLN 43.A NE2 SER 22.A OG no hydrogen 3.041 N/A GLN 43.A NE2 VAL 41.A O no hydrogen 3.029 N/A GLN 45.A N PHE 20.A O no hydrogen 2.933 N/A HIS 46.A ND1 SER 47.A O no hydrogen 3.348 N/A GLN 52.A N GLY 48.A O no hydrogen 2.819 N/A GLN 52.A NE2 SER 84.A O no hydrogen 3.029 N/A ARG 53.A N PRO 49.A O no hydrogen 3.093 N/A ARG 53.A NH1 ASP 50.A OD1 no hydrogen 3.283 N/A ARG 53.A NH2 ASP 50.A OD1 no hydrogen 3.020 N/A ASP 54.A N ASP 50.A O no hydrogen 3.080 N/A PHE 55.A N GLN 51.A O no hydrogen 2.815 N/A GLN 56.A N GLN 52.A O no hydrogen 2.929 N/A GLN 56.A NE2 GLN 60.A OE1 no hydrogen 2.913 N/A ARG 57.A N ARG 53.A O no hydrogen 3.094 N/A GLU 58.A N ASP 54.A O no hydrogen 2.943 N/A ILE 59.A N PHE 55.A O no hydrogen 3.011 N/A GLN 60.A N GLN 56.A O no hydrogen 3.013 N/A ILE 61.A N ARG 57.A O no hydrogen 2.876 N/A LEU 62.A N GLU 58.A O no hydrogen 2.896 N/A LYS 63.A N ILE 59.A O no hydrogen 2.924 N/A ALA 64.A N ILE 61.A O no hydrogen 3.180 N/A LEU 65.A N LEU 62.A O no hydrogen 3.051 N/A HIS 66.A N TYR 126.A OH no hydrogen 2.894 N/A PHE 69.A N SER 67.A OG no hydrogen 2.995 N/A ILE 70.A N SER 67.A O no hydrogen 3.244 N/A VAL 71.A N ILE 152.A O no hydrogen 2.916 N/A LYS 72.A N GLU 90.A OE2 no hydrogen 2.861 N/A ARG 74.A N VAL 88.A O no hydrogen 2.838 N/A GLY 75.A N VAL 88.A O no hydrogen 3.155 N/A VAL 76.A N THR 2.A O no hydrogen 2.896 N/A SER 77.A N ARG 86.A O no hydrogen 2.973 N/A SER 77.A OG GLU 6.A OE1 no hydrogen 2.724 N/A GLY 79.A N GLN 83.A O no hydrogen 2.901 N/A SER 84.A OG GLN 56.A OE1 no hydrogen 2.650 N/A LEU 85.A N SER 77.A O no hydrogen 2.860 N/A ARG 86.A N SER 77.A O no hydrogen 3.087 N/A ARG 86.A NE GLU 6.A OE1 no hydrogen 2.762 N/A ARG 86.A NE GLU 6.A OE2 no hydrogen 3.271 N/A ARG 86.A NH1 GLN 43.A OE1 no hydrogen 2.986 N/A ARG 86.A NH2 GLU 6.A OE2 no hydrogen 2.907 N/A LEU 87.A N LYS 42.A O no hydrogen 2.882 N/A VAL 88.A N GLY 75.A O no hydrogen 2.762 N/A MET 89.A N ALA 40.A O no hydrogen 2.781 N/A GLU 90.A N LYS 72.A O no hydrogen 3.021 N/A GLY 95.A N LEU 92.A O no hydrogen 2.975 N/A LEU 97.A N ILE 142.A O no hydrogen 2.713 N/A ARG 98.A N ALA 139.A O no hydrogen 3.272 N/A PHE 100.A N CYS 96.A O no hydrogen 2.992 N/A LEU 101.A N LEU 97.A O no hydrogen 2.846 N/A GLN 102.A N ARG 98.A O no hydrogen 3.235 N/A GLN 102.A NE2 CYS 211.A O no hydrogen 2.681 N/A ARG 103.A N ASP 99.A O no hydrogen 3.017 N/A HIS 104.A N PHE 100.A O no hydrogen 2.928 N/A ARG 107.A N HIS 104.A O no hydrogen 2.847 N/A LEU 108.A N HIS 104.A O no hydrogen 3.210 N/A LEU 108.A N ARG 105.A O no hydrogen 3.256 N/A ARG 112.A N ASP 109.A OD2 no hydrogen 3.071 N/A LEU 113.A N ASP 109.A O no hydrogen 3.121 N/A LEU 114.A N ALA 110.A O no hydrogen 2.947 N/A LEU 115.A N SER 111.A O no hydrogen 2.896 N/A TYR 116.A N ARG 112.A O no hydrogen 2.957 N/A TYR 116.A OH GLU 147.A O no hydrogen 2.555 N/A SER 117.A N LEU 113.A O no hydrogen 2.927 N/A SER 117.A OG LEU 113.A O no hydrogen 2.828 N/A SER 118.A N LEU 114.A O no hydrogen 2.876 N/A SER 118.A OG ASP 279.A OD1 no hydrogen 2.489 N/A GLN 119.A N LEU 115.A O no hydrogen 2.993 N/A GLN 119.A NE2 ALA 148.A O no hydrogen 2.995 N/A ILE 120.A N TYR 116.A O no hydrogen 2.901 N/A CYS 121.A N SER 117.A O no hydrogen 2.861 N/A CYS 121.A SG PHE 271.A O no hydrogen 3.224 N/A LYS 122.A N SER 118.A O no hydrogen 2.868 N/A GLY 123.A N GLN 119.A O no hydrogen 3.001 N/A MET 124.A N ILE 120.A O no hydrogen 2.928 N/A GLU 125.A N CYS 121.A O no hydrogen 2.812 N/A TYR 126.A N LYS 122.A O no hydrogen 3.068 N/A LEU 127.A N GLY 123.A O no hydrogen 2.890 N/A GLY 128.A N MET 124.A O no hydrogen 2.892 N/A SER 129.A N GLU 125.A O no hydrogen 3.005 N/A SER 129.A OG TYR 126.A O no hydrogen 2.605 N/A ARG 130.A N TYR 126.A O no hydrogen 3.172 N/A ARG 130.A N LEU 127.A O no hydrogen 2.970 N/A ARG 131.A N GLY 128.A O no hydrogen 3.001 N/A ARG 131.A NE LEU 161.A O no hydrogen 3.040 N/A ARG 131.A NE PRO 162.A O no hydrogen 3.317 N/A ARG 131.A NH1 PRO 162.A O no hydrogen 2.776 N/A ARG 131.A NH1 LYS 165.A O no hydrogen 3.107 N/A ARG 131.A NH1 ASP 166.A OD1 no hydrogen 2.879 N/A CYS 132.A N LEU 127.A O no hydrogen 3.069 N/A VAL 133.A N LYS 159.A O no hydrogen 2.805 N/A HIS 134.A N ASP 196.A OD1 no hydrogen 2.834 N/A HIS 134.A NE2 ALA 153.A O no hydrogen 2.860 N/A ARG 135.A N ASP 196.A OD2 no hydrogen 2.987 N/A ARG 135.A NE LEU 157.A O no hydrogen 3.088 N/A ARG 135.A NH2 LEU 157.A O no hydrogen 3.024 N/A ASP 136.A N HIS 134.A ND1 no hydrogen 3.067 N/A ALA 139.A N GLU 206.A OE2 no hydrogen 2.846 N/A ASN 141.A N ALA 138.A O no hydrogen 2.909 N/A ASN 141.A ND2 ASP 136.A O no hydrogen 2.710 N/A ILE 142.A N ALA 139.A O no hydrogen 3.315 N/A LEU 143.A N LYS 151.A O no hydrogen 2.791 N/A VAL 144.A N GLY 95.A O no hydrogen 2.837 N/A GLU 145.A N HIS 149.A O no hydrogen 2.850 N/A SER 146.A N HIS 149.A O no hydrogen 3.125 N/A ALA 148.A N SER 146.A OG no hydrogen 3.102 N/A HIS 149.A N SER 146.A O no hydrogen 3.001 N/A HIS 149.A NE2 ASP 68.A O no hydrogen 2.660 N/A VAL 150.A N GLN 119.A OE1 no hydrogen 2.936 N/A LYS 151.A N LEU 143.A O no hydrogen 2.873 N/A LYS 151.A NZ GLU 90.A OE1 no hydrogen 3.488 N/A LYS 151.A NZ GLU 90.A OE2 no hydrogen 2.765 N/A ILE 152.A N PHE 69.A O no hydrogen 2.894 N/A ALA 153.A N ASN 141.A O no hydrogen 3.033 N/A ALA 158.A N PHE 155.A O no hydrogen 3.106 N/A LYS 159.A N VAL 133.A O no hydrogen 2.910 N/A LEU 161.A N ARG 131.A O no hydrogen 2.695 N/A LYS 165.A N PRO 162.A O no hydrogen 3.269 N/A TYR 168.A N PHE 191.A O no hydrogen 2.880 N/A VAL 170.A N ASN 189.A O no hydrogen 3.058 N/A GLN 175.A NE2 GLN 175.A O no hydrogen 3.302 N/A SER 176.A N TYR 181.A OH no hydrogen 3.086 N/A SER 176.A OG ASP 136.A OD1 no hydrogen 3.053 N/A TRP 180.A NE1 GLU 206.A OE2 no hydrogen 2.917 N/A TYR 181.A N ILE 178.A O no hydrogen 3.256 N/A GLU 184.A N GLU 184.A OE2 no hydrogen 2.771 N/A SER 185.A N ALA 182.A O no hydrogen 2.976 N/A SER 185.A OG ILE 190.A O no hydrogen 2.761 N/A LEU 186.A N ALA 182.A O no hydrogen 2.974 N/A SER 187.A N PRO 183.A O no hydrogen 2.842 N/A SER 187.A OG PRO 183.A O no hydrogen 3.178 N/A SER 187.A OG ASP 188.A OD2 no hydrogen 2.713 N/A ASP 188.A N GLU 184.A O no hydrogen 2.932 N/A ASN 189.A N SER 185.A O no hydrogen 2.985 N/A ASN 189.A ND2 VAL 170.A O no hydrogen 3.497 N/A ASN 189.A ND2 ARG 171.A O no hydrogen 3.664 N/A ILE 190.A N GLU 184.A O no hydrogen 3.311 N/A PHE 191.A N TYR 168.A O no hydrogen 2.812 N/A SER 192.A N SER 195.A OG no hydrogen 2.795 N/A SER 192.A OG GLN 194.A OE1.A no hydrogen 2.904 N/A ARG 193.A NH1 GLY 128.A O no hydrogen 2.988 N/A GLN 194.A N SER 192.A OG no hydrogen 3.001 N/A SER 195.A N SER 192.A OG no hydrogen 3.191 N/A SER 195.A OG SER 192.A O no hydrogen 2.817 N/A ASP 196.A N SER 192.A O no hydrogen 3.094 N/A VAL 197.A N ARG 193.A O no hydrogen 3.085 N/A TRP 198.A N GLN 194.A O no hydrogen 3.255 N/A SER 199.A N SER 195.A O no hydrogen 3.097 N/A SER 199.A OG TRP 180.A O no hydrogen 2.759 N/A SER 199.A OG SER 195.A O no hydrogen 3.419 N/A PHE 200.A N ASP 196.A O no hydrogen 2.821 N/A GLY 201.A N VAL 197.A O no hydrogen 3.021 N/A VAL 202.A N TRP 198.A O no hydrogen 3.242 N/A VAL 203.A N SER 199.A O no hydrogen 2.833 N/A LEU 204.A N PHE 200.A O no hydrogen 2.813 N/A TYR 205.A N GLY 201.A O no hydrogen 3.013 N/A TYR 205.A OH CYS 215.A O no hydrogen 2.572 N/A GLU 206.A N VAL 202.A O no hydrogen 2.864 N/A LEU 207.A N VAL 203.A O no hydrogen 2.808 N/A PHE 208.A N LEU 204.A O no hydrogen 3.031 N/A THR 209.A N TYR 205.A O no hydrogen 3.041 N/A THR 209.A N GLU 206.A O no hydrogen 3.336 N/A THR 209.A OG1 TYR 205.A O no hydrogen 2.949 N/A THR 209.A OG1 GLU 206.A O no hydrogen 3.062 N/A TYR 210.A N LEU 207.A O no hydrogen 3.017 N/A TYR 210.A OH LEU 108.A O no hydrogen 2.604 N/A CYS 211.A N GLU 206.A O no hydrogen 2.882 N/A CYS 211.A SG GLU 206.A O no hydrogen 3.898 N/A CYS 211.A SG GLU 206.A OE1 no hydrogen 3.755 N/A ASP 212.A N THR 209.A O no hydrogen 2.937 N/A SER 214.A N ASP 212.A OD1 no hydrogen 2.830 N/A SER 214.A OG ASP 212.A OD1 no hydrogen 2.703 N/A SER 216.A N LYS 213.A O no hydrogen 3.332 N/A SER 216.A OG LYS 213.A O no hydrogen 3.064 N/A SER 216.A OG SER 218.A OG no hydrogen 3.100 N/A SER 218.A OG SER 216.A OG no hydrogen 3.100 N/A ALA 219.A N SER 216.A OG no hydrogen 3.119 N/A GLU 220.A N SER 216.A O no hydrogen 2.801 N/A PHE 221.A N PRO 217.A O no hydrogen 2.936 N/A LEU 222.A N SER 218.A O no hydrogen 2.908 N/A ARG 223.A N ALA 219.A O no hydrogen 3.027 N/A ARG 223.A NE GLU 220.A OE1 no hydrogen 2.885 N/A ARG 223.A NE GLU 220.A OE2 no hydrogen 3.416 N/A ARG 223.A NH1 GLU 220.A OE2 no hydrogen 2.700 N/A MET 224.A N GLU 220.A O no hydrogen 2.846 N/A MET 225.A N PHE 221.A O no hydrogen 2.804 N/A ARG 232.A N PRO 228.A O no hydrogen 2.771 N/A LEU 233.A N ALA 229.A O no hydrogen 2.720 N/A LEU 234.A N LEU 230.A O no hydrogen 2.868 N/A GLU 235.A N SER 231.A O no hydrogen 2.920 N/A LEU 236.A N ARG 232.A O no hydrogen 3.041 N/A LEU 237.A N LEU 233.A O no hydrogen 2.967 N/A GLU 238.A N LEU 234.A O no hydrogen 2.871 N/A GLU 239.A N GLU 235.A O no hydrogen 2.910 N/A GLY 240.A N LEU 237.A O no hydrogen 2.927 N/A GLN 241.A N LEU 236.A O no hydrogen 3.072 N/A GLN 241.A NE2 GLU 239.A OE2 no hydrogen 3.548 N/A ARG 242.A NE TRP 261.A O no hydrogen 3.110 N/A ARG 242.A NH1 TRP 261.A O no hydrogen 2.945 N/A ARG 242.A NH2 LEU 237.A O no hydrogen 2.916 N/A ARG 242.A NH2 GLN 241.A O no hydrogen 2.903 N/A CYS 249.A N PRO 246.A O no hydrogen 2.991 N/A CYS 249.A SG PRO 250.A O no hydrogen 3.502 N/A VAL 253.A N PRO 250.A O no hydrogen 2.992 N/A HIS 254.A N PRO 250.A O no hydrogen 3.171 N/A GLU 255.A N ALA 251.A O no hydrogen 2.945 N/A LEU 256.A N GLU 252.A O no hydrogen 3.200 N/A MET 257.A N VAL 253.A O no hydrogen 3.030 N/A LYS 258.A N HIS 254.A O no hydrogen 3.081 N/A LYS 258.A NZ GLU 255.A OE1 no hydrogen 3.298 N/A LYS 258.A NZ GLU 255.A OE2 no hydrogen 2.920 N/A LEU 259.A N GLU 255.A O no hydrogen 3.101 N/A CYS 260.A N LEU 256.A O no hydrogen 3.031 N/A CYS 260.A SG LEU 256.A O no hydrogen 3.432 N/A TRP 261.A N MET 257.A O no hydrogen 3.040 N/A TRP 261.A N LYS 258.A O no hydrogen 3.197 N/A ALA 262.A N LEU 259.A O no hydrogen 3.164 N/A ASP 267.A N SER 264.A O no hydrogen 2.944 N/A ARG 268.A N PRO 265.A O no hydrogen 3.132 N/A ARG 268.A NE ALA 262.A O no hydrogen 2.850 N/A ARG 268.A NH1 GLU 184.A OE2 no hydrogen 2.934 N/A ARG 268.A NH1 ALA 262.A O no hydrogen 3.156 N/A ARG 268.A NH1 PRO 263.A O no hydrogen 3.080 N/A ARG 268.A NH2 GLU 184.A OE1 no hydrogen 2.826 N/A ARG 268.A NH2 GLU 184.A OE2 no hydrogen 3.502 N/A ARG 268.A NH2 GLN 194.A O no hydrogen 3.047 N/A SER 270.A OG SER 272.A OG no hydrogen 2.666 N/A SER 272.A OG SER 270.A OG no hydrogen 2.666 N/A ALA 273.A N SER 270.A OG no hydrogen 2.993 N/A LEU 274.A N SER 270.A O no hydrogen 2.941 N/A GLY 275.A N PHE 271.A O no hydrogen 3.053 N/A GLN 277.A NE2 ALA 273.A O no hydrogen 3.084 N/A LEU 278.A N LEU 274.A O no hydrogen 3.015 N/A ASP 279.A N GLY 275.A O no hydrogen 2.935 N/A MET 280.A N PRO 276.A O no hydrogen 2.847 N/A LEU 281.A N GLN 277.A O no hydrogen 3.190 N/A