Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3mfd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 5.A N ASP 218.A OD2 no hydrogen 2.844 N/A LYS 7.A N ASN 211.A O no hydrogen 2.949 N/A SER 8.A N ILE 210.A O no hydrogen 3.290 N/A SER 8.A OG ASP 24.A O no hydrogen 2.694 N/A ALA 9.A N LYS 23.A O no hydrogen 2.897 N/A ILE 10.A N VAL 208.A O no hydrogen 2.897 N/A ILE 11.A N TYR 21.A O no hydrogen 2.926 N/A ILE 12.A N ILE 206.A O no hydrogen 2.891 N/A ASP 13.A N ARG 18.A O no hydrogen 2.910 N/A GLY 14.A N ASP 204.A O no hydrogen 2.771 N/A ALA 15.A N ASP 13.A OD1 no hydrogen 2.997 N/A SER 16.A N ASP 13.A OD2 no hydrogen 3.273 N/A SER 16.A OG ASP 13.A OD2 no hydrogen 2.581 N/A GLY 17.A N ASP 13.A O no hydrogen 2.769 N/A ARG 18.A N SER 16.A OG no hydrogen 2.970 N/A ARG 18.A NH1 LEU 260.A O no hydrogen 2.959 N/A ARG 18.A NH1 GLU 265.A OE1 no hydrogen 2.914 N/A ARG 18.A NH2 GLU 265.A OE2 no hydrogen 2.980 N/A LEU 20.A N ILE 11.A O no hydrogen 2.890 N/A TYR 21.A N ILE 11.A O no hydrogen 3.417 N/A LYS 23.A N ALA 9.A O no hydrogen 2.896 N/A LYS 23.A NZ VAL 4.A O no hydrogen 3.120 N/A LYS 23.A NZ ALA 6.A O no hydrogen 2.856 N/A GLU 25.A N GLU 25.A OE1 no hydrogen 2.701 N/A GLN 27.A N ASP 24.A O no hydrogen 3.393 N/A GLN 27.A NE2 LYS 28.A O no hydrogen 3.022 N/A LYS 28.A NZ ASN 116.A OD1 no hydrogen 3.078 N/A ARG 29.A N SER 133.A O no hydrogen 2.896 N/A ARG 29.A NE SER 8.A OG no hydrogen 2.797 N/A ARG 29.A NH2 ASP 24.A OD2 no hydrogen 2.920 N/A ARG 30.A NH2 ASP 126.A OD1 no hydrogen 3.135 N/A SER 33.A OG SER 85.A OG no hydrogen 3.017 N/A THR 35.A N ALA 32.A O no hydrogen 3.114 N/A THR 35.A OG1 ALA 32.A O no hydrogen 2.702 N/A THR 35.A OG1 HIS 131.A NE2 no hydrogen 2.911 N/A LYS 36.A N SER 33.A O no hydrogen 2.906 N/A LYS 36.A NZ SER 33.A OG no hydrogen 2.744 N/A LYS 36.A NZ SER 85.A O no hydrogen 3.450 N/A LYS 36.A NZ SER 85.A OG no hydrogen 3.157 N/A LYS 36.A NZ ASN 87.A OD1 no hydrogen 2.576 N/A LYS 36.A NZ HIS 123.A O no hydrogen 3.066 N/A ILE 37.A N ILE 34.A O no hydrogen 3.073 N/A THR 38.A OG1 PRO 122.A O no hydrogen 2.707 N/A ALA 39.A N LYS 36.A O no hydrogen 2.887 N/A VAL 40.A N ILE 37.A O no hydrogen 2.971 N/A ALA 42.A N THR 38.A O no hydrogen 3.064 N/A ILE 43.A N ALA 39.A O no hydrogen 2.887 N/A GLU 44.A N VAL 40.A O no hydrogen 2.906 N/A SER 45.A N ALA 42.A O no hydrogen 3.257 N/A SER 45.A OG ALA 42.A O no hydrogen 2.739 N/A LYS 47.A N SER 45.A OG no hydrogen 2.975 N/A GLN 49.A N LYS 47.A O no hydrogen 2.937 N/A VAL 51.A N VAL 73.A O no hydrogen 2.740 N/A VAL 53.A N GLN 71.A O no hydrogen 2.974 N/A SER 54.A OG GLU 95.A OE1 no hydrogen 2.592 N/A ASN 56.A ND2 GLU 95.A OE2 no hydrogen 2.999 N/A ALA 57.A N SER 54.A OG no hydrogen 3.037 N/A VAL 58.A N SER 54.A O no hydrogen 3.162 N/A ARG 59.A N ALA 55.A O no hydrogen 3.097 N/A THR 60.A N ALA 57.A O no hydrogen 3.300 N/A THR 60.A OG1 ASN 56.A O no hydrogen 3.210 N/A THR 60.A OG1 ALA 57.A O no hydrogen 2.793 N/A ILE 65.A N ASP 88.A OD1 no hydrogen 2.956 N/A LEU 67.A N ASP 88.A OD2 no hydrogen 3.050 N/A THR 68.A N GLN 71.A OE1 no hydrogen 2.923 N/A THR 68.A OG1 GLN 71.A OE1 no hydrogen 3.364 N/A GLY 70.A N VAL 53.A O no hydrogen 2.713 N/A GLN 71.A N THR 68.A O no hydrogen 3.111 N/A LYS 72.A NZ THR 52.A OG1 no hydrogen 2.898 N/A VAL 73.A N VAL 51.A O no hydrogen 2.964 N/A LYS 74.A N THR 162.A OG1 no hydrogen 3.011 N/A LYS 74.A NZ GLU 161.A OE2.B no hydrogen 3.210 N/A LEU 75.A N GLN 49.A O no hydrogen 2.870 N/A LYS 76.A NZ GLU 161.A OE2.A no hydrogen 2.498 N/A LEU 78.A N LYS 74.A O no hydrogen 3.316 N/A VAL 79.A N LEU 75.A O no hydrogen 2.999 N/A TYR 80.A N LYS 76.A O no hydrogen 3.076 N/A GLY 81.A N ASP 77.A O no hydrogen 2.911 N/A LEU 82.A N LEU 78.A O no hydrogen 2.757 N/A ARG 84.A N GLY 81.A O no hydrogen 3.016 N/A ARG 84.A NH1 LYS 167.A O no hydrogen 2.893 N/A SER 85.A OG SER 33.A OG no hydrogen 3.017 N/A GLY 86.A N GLY 81.A O no hydrogen 3.471 N/A ASN 87.A N SER 63.A O no hydrogen 2.939 N/A ASN 87.A ND2 GLU 61.A O no hydrogen 2.977 N/A ALA 89.A N ASP 88.A OD1 no hydrogen 2.969 N/A ALA 90.A N GLY 86.A O no hydrogen 3.053 N/A VAL 91.A N ASN 87.A O no hydrogen 3.063 N/A ALA 92.A N ASP 88.A O no hydrogen 2.947 N/A ILE 93.A N ALA 89.A O no hydrogen 2.845 N/A ALA 94.A N ALA 90.A O no hydrogen 2.928 N/A GLU 95.A N VAL 91.A O no hydrogen 2.895 N/A HIS 96.A N ALA 92.A O no hydrogen 2.980 N/A HIS 96.A NE2 GLN 49.A OE1 no hydrogen 2.787 N/A VAL 97.A N ILE 93.A O no hydrogen 2.808 N/A GLY 98.A N ALA 94.A O no hydrogen 2.760 N/A GLY 103.A N SER 100.A OG no hydrogen 2.936 N/A PHE 104.A N SER 100.A O no hydrogen 2.956 N/A VAL 105.A N LEU 101.A O no hydrogen 2.851 N/A TYR 106.A N ASP 102.A O no hydrogen 3.006 N/A ASN 107.A ND2 PHE 119.A O no hydrogen 2.895 N/A GLN 108.A N.A TYR 106.A O no hydrogen 2.898 N/A GLN 108.A N.B TYR 106.A O no hydrogen 2.852 N/A LYS 109.A NZ GLU 44.A OE1 no hydrogen 2.982 N/A LYS 109.A NZ GLN 112.A OE1.B no hydrogen 3.233 N/A LYS 109.A NZ TYR 143.A OH no hydrogen 2.923 N/A GLU 111.A N ASN 107.A O no hydrogen 2.959 N/A GLN 112.A N GLN 108.A O.A no hydrogen 3.036 N/A GLN 112.A N GLN 108.A O.B no hydrogen 2.980 N/A LEU 113.A N LYS 109.A O no hydrogen 2.994 N/A GLY 114.A N GLU 111.A O no hydrogen 3.113 N/A LYS 115.A N.A ASP 137.A OD2 no hydrogen 3.398 N/A LYS 115.A N.B ASP 137.A OD2 no hydrogen 3.357 N/A ASN 116.A N ASP 137.A OD2 no hydrogen 2.852 N/A THR 117.A OG1 SER 133.A OG no hydrogen 2.723 N/A THR 117.A OG1 ASP 137.A OD2 no hydrogen 2.739 N/A ARG 118.A N TYR 132.A O no hydrogen 2.951 N/A PHE 119.A N ASN 107.A OD1 no hydrogen 2.889 N/A GLN 120.A N HIS 131.A ND1 no hydrogen 2.853 N/A GLN 120.A NE2 ASN 130.A O.A no hydrogen 2.906 N/A GLN 120.A NE2 ASN 130.A O.B no hydrogen 2.976 N/A ASN 121.A ND2 LEU 125.A O no hydrogen 2.928 N/A ASN 121.A ND2 ASP 127.A OD1 no hydrogen 2.839 N/A HIS 123.A N ASN 121.A OD1 no hydrogen 2.940 N/A GLY 124.A N ASN 121.A OD1 no hydrogen 2.738 N/A LEU 125.A N HIS 123.A ND1 no hydrogen 3.176 N/A HIS 128.A ND1 ASP 127.A OD1 no hydrogen 2.663 N/A HIS 131.A NE2 THR 35.A OG1 no hydrogen 2.911 N/A TYR 132.A N ARG 118.A O no hydrogen 2.909 N/A SER 133.A N ARG 29.A O no hydrogen 3.125 N/A SER 133.A OG THR 117.A OG1 no hydrogen 2.723 N/A THR 134.A N SER 133.A OG no hydrogen 2.739 N/A THR 134.A OG1 GLU 25.A O no hydrogen 3.414 N/A TYR 136.A N GLU 25.A O no hydrogen 2.958 N/A ASP 137.A N THR 134.A OG1 no hydrogen 2.944 N/A ILE 139.A N TYR 136.A O no hydrogen 3.119 N/A LEU 140.A N ASP 137.A O no hydrogen 2.976 N/A LYS 142.A N ALA 138.A O no hydrogen 2.918 N/A TYR 143.A N ILE 139.A O no hydrogen 3.085 N/A TYR 143.A OH GLU 44.A OE2 no hydrogen 2.524 N/A ALA 144.A N LEU 140.A O no hydrogen 2.815 N/A LEU 146.A N ALA 144.A O no hydrogen 2.951 N/A GLN 150.A N.A LEU 146.A O no hydrogen 2.966 N/A GLN 150.A N.B LEU 146.A O no hydrogen 2.996 N/A LYS 151.A N LYS 147.A O no hydrogen 2.984 N/A ILE 152.A N ASP 148.A O no hydrogen 2.937 N/A SER 153.A N TYR 149.A O no hydrogen 2.802 N/A GLY 154.A N GLN 150.A O.A no hydrogen 3.124 N/A GLY 154.A N GLN 150.A O.B no hydrogen 3.107 N/A THR 155.A N ILE 152.A O no hydrogen 3.057 N/A THR 155.A OG1 LYS 151.A O no hydrogen 2.663 N/A THR 155.A OG1 ILE 152.A O no hydrogen 3.557 N/A TYR 158.A N TRP 166.A O no hydrogen 2.913 N/A TYR 158.A OH ASP 77.A OD1 no hydrogen 2.681 N/A LYS 159.A NZ ALA 160.A O no hydrogen 2.716 N/A ALA 160.A N SER 164.A O no hydrogen 3.026 N/A GLU 161.A N ASP 77.A OD1 no hydrogen 2.883 N/A THR 162.A N ASP 77.A OD2 no hydrogen 2.685 N/A THR 162.A OG1 ASP 77.A OD2 no hydrogen 2.574 N/A TRP 166.A N TYR 158.A O no hydrogen 2.770 N/A ASN 168.A N LYS 156.A O no hydrogen 2.900 N/A ASN 168.A ND2 THR 155.A O no hydrogen 2.911 N/A LYS 169.A N LEU 83.A O no hydrogen 2.996 N/A LYS 169.A NZ ARG 84.A O no hydrogen 2.788 N/A ASN 170.A N ASN 168.A OD1 no hydrogen 2.819 N/A LEU 173.A N ASN 170.A O no hydrogen 3.110 N/A LEU 173.A N ASN 170.A OD1 no hydrogen 3.461 N/A THR 174.A N ASN 170.A O no hydrogen 3.093 N/A THR 174.A OG1 ASN 170.A O no hydrogen 3.506 N/A TYR 176.A N LEU 172.A O no hydrogen 3.014 N/A TYR 176.A OH ASN 222.A OD1 no hydrogen 2.646 N/A SER 179.A N TYR 176.A O no hydrogen 3.102 N/A THR 180.A N THR 197.A O no hydrogen 2.931 N/A THR 180.A OG1 THR 197.A OG1 no hydrogen 2.754 N/A GLY 182.A N SER 153.A OG no hydrogen 2.975 N/A LYS 183.A N VAL 195.A O no hydrogen 2.787 N/A LYS 183.A NZ SER 85.A OG no hydrogen 2.977 N/A LYS 183.A NZ THR 184.A O no hydrogen 2.767 N/A GLY 185.A N THR 193.A O no hydrogen 2.855 N/A THR 187.A OG1 ASP 126.A OD2 no hydrogen 2.590 N/A ALA 190.A N THR 187.A OG1 no hydrogen 2.855 N/A LYS 191.A N THR 187.A O no hydrogen 2.825 N/A LYS 191.A NZ LYS 188.A O no hydrogen 3.182 N/A LYS 191.A NZ LEU 189.A O no hydrogen 3.371 N/A ARG 192.A NE ASP 215.A OD1 no hydrogen 2.994 N/A ARG 192.A NE ASP 215.A OD2 no hydrogen 3.307 N/A ARG 192.A NH2 ASP 215.A OD1 no hydrogen 3.137 N/A THR 193.A N GLY 185.A O no hydrogen 2.851 N/A THR 193.A OG1 ILE 31.A O no hydrogen 2.764 N/A LEU 194.A N THR 209.A O no hydrogen 2.890 N/A VAL 195.A N LYS 183.A O no hydrogen 2.999 N/A SER 196.A N ALA 207.A O no hydrogen 2.899 N/A SER 196.A OG HIS 219.A ND1 no hydrogen 2.799 N/A THR 197.A N GLY 181.A O no hydrogen 3.086 N/A THR 197.A OG1 THR 180.A OG1 no hydrogen 2.754 N/A ALA 198.A N LEU 205.A O no hydrogen 3.084 N/A SER 199.A N TYR 178.A O no hydrogen 2.961 N/A SER 199.A OG ASP 204.A OD1 no hydrogen 2.517 N/A LYS 200.A N ILE 203.A O no hydrogen 3.011 N/A ILE 203.A N LYS 200.A O no hydrogen 2.896 N/A LEU 205.A N ALA 198.A O no hydrogen 2.784 N/A ILE 206.A N ILE 12.A O no hydrogen 3.079 N/A ALA 207.A N SER 196.A O no hydrogen 2.864 N/A VAL 208.A N ILE 10.A O no hydrogen 2.947 N/A THR 209.A N LEU 194.A O no hydrogen 2.842 N/A THR 209.A OG1 HIS 219.A NE2 no hydrogen 2.899 N/A ILE 210.A N SER 8.A O no hydrogen 2.919 N/A ASN 211.A N ARG 192.A O no hydrogen 2.790 N/A ASP 212.A N ARG 192.A O no hydrogen 3.030 N/A ASN 214.A N ASP 212.A OD1 no hydrogen 2.910 N/A ASN 214.A ND2.A SER 5.A OG no hydrogen 2.767 N/A ASN 214.A ND2.B ASP 217.A OD2 no hydrogen 3.162 N/A ASP 218.A N ASN 214.A O no hydrogen 2.969 N/A HIS 219.A N ASP 215.A O no hydrogen 2.824 N/A HIS 219.A ND1 SER 196.A OG no hydrogen 2.799 N/A HIS 219.A NE2 THR 209.A OG1 no hydrogen 2.899 N/A LYS 220.A NZ ASP 3.A O no hydrogen 3.065 N/A TYR 223.A N LYS 220.A O no hydrogen 2.928 N/A PHE 225.A N PHE 221.A O no hydrogen 2.823 N/A GLU 226.A N ASN 222.A O no hydrogen 2.909 N/A HIS 227.A N TYR 223.A O no hydrogen 2.952 N/A HIS 227.A ND1 TYR 223.A O no hydrogen 2.913 N/A TYR 228.A N VAL 224.A O no hydrogen 2.909 N/A GLN 229.A N LEU 261.A O no hydrogen 3.045 N/A TYR 231.A N TYR 259.A O no hydrogen 2.887 N/A ILE 233.A N ILE 257.A O no hydrogen 2.763 N/A ALA 234.A N ILE 257.A O no hydrogen 3.296 N/A LYS 236.A N ASP 256.A OD1 no hydrogen 2.776 N/A GLY 237.A N ILE 253.A O no hydrogen 2.985 N/A LYS 241.A NZ THR 273.A OG1 no hydrogen 2.730 N/A LEU 242.A N ILE 239.A O no hydrogen 3.042 N/A LYS 243.A N PRO 240.A O no hydrogen 3.021 N/A GLY 244.A N GLU 248.A OE1 no hydrogen 2.732 N/A THR 245.A N LEU 242.A O no hydrogen 3.080 N/A THR 245.A OG1 LEU 242.A O no hydrogen 2.663 N/A TYR 247.A N THR 245.A OG1 no hydrogen 3.252 N/A TYR 247.A OH LEU 276.A O no hydrogen 2.669 N/A GLU 248.A N THR 245.A O no hydrogen 3.151 N/A ALA 251.A N TYR 247.A O no hydrogen 3.282 N/A PHE 252.A N TYR 309.A O no hydrogen 2.942 N/A ILE 253.A N GLY 237.A O no hydrogen 2.918 N/A ARG 255.A NH1 ASP 256.A O no hydrogen 3.124 N/A ILE 257.A N ALA 234.A O no hydrogen 2.818 N/A TYR 259.A N TYR 231.A O no hydrogen 2.967 N/A LEU 261.A N GLN 229.A O no hydrogen 3.047 N/A THR 262.A N GLU 265.A OE1 no hydrogen 3.039 N/A GLU 265.A N THR 262.A OG1 no hydrogen 3.044 N/A LYS 266.A N THR 262.A O no hydrogen 2.962 N/A ASN 268.A N GLU 265.A O no hydrogen 2.936 N/A VAL 269.A N LYS 266.A O no hydrogen 3.363 N/A ASN 272.A N GLU 296.A O no hydrogen 2.873 N/A THR 274.A N HIS 295.A O no hydrogen 2.946 N/A LEU 276.A N VAL 293.A O no hydrogen 2.813 N/A TRP 282.A N LYS 279.A O no hydrogen 2.813 N/A GLU 283.A N LYS 280.A O no hydrogen 2.941 N/A ASP 285.A N ALA 281.A O no hydrogen 3.267 N/A SER 287.A N ASP 285.A OD1 no hydrogen 3.000 N/A SER 287.A OG ASP 285.A OD1 no hydrogen 2.779 N/A SER 287.A OG ASP 285.A OD2 no hydrogen 3.456 N/A LYS 288.A N ASP 285.A O no hydrogen 3.436 N/A ILE 289.A N ALA 286.A O no hydrogen 3.032 N/A VAL 293.A N ILE 308.A O no hydrogen 2.827 N/A HIS 295.A N THR 274.A O no hydrogen 2.965 N/A ILE 297.A N ALA 304.A O no hydrogen 2.792 N/A ALA 301.A N PHE 298.A O no hydrogen 2.817 N/A ILE 303.A N ILE 297.A O no hydrogen 2.913 N/A ALA 304.A N ILE 297.A O no hydrogen 3.454 N/A ILE 308.A N GLY 294.A O no hydrogen 2.872 N/A TYR 309.A N PHE 252.A O no hydrogen 2.833 N/A TYR 310.A N ASP 291.A O no hydrogen 2.924 N/A GLU 311.A N LYS 250.A O no hydrogen 2.939 N/A