Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3mkm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A NZ PRO 27.A O no hydrogen 2.754 N/A ARG 4.A N ALA 28.A O no hydrogen 2.962 N/A ARG 4.A NH2 THR 120.A OG1 no hydrogen 2.900 N/A ARG 4.A NH2 GLU 146.A OE1 no hydrogen 2.910 N/A LYS 5.A NZ ASP 118.A OD2 no hydrogen 2.823 N/A ILE 6.A N ASP 30.A O no hydrogen 2.984 N/A ILE 7.A N THR 120.A O no hydrogen 3.094 N/A LEU 8.A N GLY 33.A O no hydrogen 3.204 N/A ASP 9.A N VAL 122.A O no hydrogen 2.984 N/A CYS 10.A N THR 35.A O no hydrogen 2.996 N/A CYS 10.A SG THR 35.A O no hydrogen 3.929 N/A ASP 11.A N ASP 16.A OD1 no hydrogen 3.189 N/A GLY 13.A N GLY 86.A O no hydrogen 2.885 N/A HIS 14.A ND1 HIS 82.A ND1 no hydrogen 2.857 N/A HIS 14.A NE2 ASP 88.A O no hydrogen 2.720 N/A ALA 17.A N GLY 13.A O no hydrogen 3.073 N/A ILE 18.A N HIS 14.A O no hydrogen 3.437 N/A ALA 19.A N ASP 15.A O no hydrogen 2.817 N/A ILE 20.A N ASP 16.A O no hydrogen 2.816 N/A MET 21.A N ALA 17.A O no hydrogen 3.052 N/A MET 22.A N ILE 18.A O no hydrogen 3.078 N/A ALA 23.A N ALA 19.A O no hydrogen 2.968 N/A ALA 24.A N ILE 20.A O no hydrogen 2.917 N/A LYS 25.A N MET 22.A O no hydrogen 3.212 N/A LYS 25.A NZ GLY 308.A O no hydrogen 3.519 N/A HIS 26.A N MET 22.A O no hydrogen 3.159 N/A HIS 26.A NE2 GLU 304.A OE1 no hydrogen 3.113 N/A ALA 28.A N HIS 26.A ND1 no hydrogen 3.030 N/A ILE 29.A N HIS 26.A O no hydrogen 3.056 N/A ASP 30.A N ARG 4.A O no hydrogen 2.775 N/A LEU 32.A N ILE 6.A O no hydrogen 2.957 N/A ILE 34.A N PRO 62.A O no hydrogen 3.004 N/A THR 35.A N LEU 8.A O no hydrogen 2.900 N/A THR 35.A OG1 ASP 9.A OD1 no hydrogen 2.588 N/A ILE 36.A N TYR 64.A O no hydrogen 2.863 N/A VAL 37.A N CYS 10.A O no hydrogen 3.046 N/A ALA 38.A N MET 67.A O no hydrogen 3.012 N/A GLY 39.A N GLN 41.A O no hydrogen 2.931 N/A ASN 40.A N ASP 11.A OD2 no hydrogen 2.947 N/A ASN 40.A ND2 ASP 11.A O no hydrogen 2.827 N/A GLN 41.A NE2 GLY 83.A O no hydrogen 3.549 N/A THR 42.A N GLN 41.A OE1 no hydrogen 3.145 N/A THR 42.A OG1 ASP 44.A OD1 no hydrogen 2.391 N/A LYS 45.A N THR 42.A O no hydrogen 3.084 N/A LYS 45.A NZ ASP 84.A O no hydrogen 2.583 N/A THR 46.A N THR 42.A O no hydrogen 3.070 N/A THR 46.A OG1 VAL 37.A O no hydrogen 3.065 N/A THR 46.A OG1 LEU 43.A O no hydrogen 3.429 N/A LEU 47.A N LEU 43.A O no hydrogen 2.922 N/A ILE 48.A N ASP 44.A O no hydrogen 3.375 N/A ASN 49.A N LYS 45.A O no hydrogen 2.894 N/A ASN 49.A ND2 PRO 12.A O no hydrogen 2.853 N/A ASN 49.A ND2 THR 85.A O no hydrogen 2.838 N/A GLY 50.A N THR 46.A O no hydrogen 2.969 N/A LEU 51.A N LEU 47.A O no hydrogen 2.993 N/A ASN 52.A N ILE 48.A O no hydrogen 2.864 N/A VAL 53.A N ASN 49.A O no hydrogen 3.062 N/A CYS 54.A N GLY 50.A O no hydrogen 3.128 N/A CYS 54.A SG GLY 50.A O no hydrogen 3.496 N/A GLN 55.A N LEU 51.A O no hydrogen 2.859 N/A GLN 55.A NE2 PRO 94.A O no hydrogen 2.890 N/A LYS 56.A N ASN 52.A O no hydrogen 2.955 N/A LYS 56.A NZ VAL 91.A O no hydrogen 2.830 N/A LEU 57.A N VAL 53.A O no hydrogen 3.049 N/A GLU 58.A N GLN 55.A O no hydrogen 3.186 N/A ILE 59.A N CYS 54.A O no hydrogen 2.857 N/A TYR 64.A N ILE 34.A O no hydrogen 2.865 N/A GLY 66.A N ILE 36.A O no hydrogen 2.875 N/A MET 67.A N ASN 129.A OD1 no hydrogen 2.720 N/A GLN 69.A NE2.B GLN 75.A OE1 no hydrogen 2.821 N/A ILE 71.A N ASP 170.A OD2 no hydrogen 3.063 N/A ARG 73.A NE GLN 74.A O no hydrogen 2.855 N/A ARG 73.A NH1 PHE 168.A O no hydrogen 2.787 N/A ARG 73.A NH2 GLN 74.A O no hydrogen 3.440 N/A GLN 75.A NE2 PRO 68.A O no hydrogen 3.200 N/A ALA 78.A N ASN 40.A O no hydrogen 2.980 N/A ASN 80.A ND2 ASN 230.A OD1 no hydrogen 3.283 N/A ILE 81.A N ALA 78.A O no hydrogen 3.178 N/A HIS 82.A N ALA 78.A O no hydrogen 3.074 N/A HIS 82.A ND1 HIS 14.A ND1 no hydrogen 2.857 N/A GLY 83.A N ASP 79.A O no hydrogen 2.889 N/A THR 85.A N ASP 88.A OD1 no hydrogen 3.185 N/A THR 85.A OG1 ASP 88.A OD1 no hydrogen 2.554 N/A GLY 86.A N GLY 83.A O no hydrogen 3.160 N/A LEU 87.A N THR 85.A OG1 no hydrogen 3.021 N/A THR 96.A N GLN 55.A OE1 no hydrogen 2.761 N/A THR 96.A OG1 GLN 55.A OE1 no hydrogen 3.368 N/A ARG 97.A NH1 ILE 59.A O no hydrogen 2.806 N/A ARG 97.A NH2 ILE 59.A O no hydrogen 3.165 N/A ARG 97.A NH2 ASN 60.A OD1 no hydrogen 3.446 N/A GLU 100.A N VAL 63.A O no hydrogen 2.957 N/A ALA 104.A N ALA 65.A O no hydrogen 2.841 N/A VAL 105.A N HIS 103.A ND1 no hydrogen 3.174 N/A LYS 106.A NZ ASP 110.A OD2 no hydrogen 2.643 N/A TYR 107.A N HIS 103.A O no hydrogen 2.994 N/A ILE 108.A N ALA 104.A O no hydrogen 2.898 N/A ILE 109.A N VAL 105.A O no hydrogen 3.022 N/A ASP 110.A N LYS 106.A O no hydrogen 2.830 N/A THR 111.A N TYR 107.A O no hydrogen 3.041 N/A THR 111.A OG1 TYR 107.A O no hydrogen 2.576 N/A LEU 112.A N ILE 108.A O no hydrogen 3.099 N/A MET 113.A N ILE 109.A O no hydrogen 2.908 N/A ALA 114.A N ASP 110.A O no hydrogen 3.038 N/A SER 115.A N LEU 112.A O no hydrogen 3.015 N/A SER 115.A OG LEU 112.A O no hydrogen 2.653 N/A GLY 117.A N SER 115.A OG no hydrogen 3.154 N/A THR 120.A N LYS 5.A O no hydrogen 3.007 N/A LEU 121.A N GLU 146.A O no hydrogen 3.094 N/A VAL 122.A N ILE 7.A O no hydrogen 2.847 N/A VAL 124.A N ASP 9.A O no hydrogen 2.795 N/A SER 128.A OG ASP 170.A OD2 no hydrogen 2.647 N/A ASN 129.A ND2 ASP 9.A OD1 no hydrogen 2.797 N/A ASN 129.A ND2 ILE 36.A O no hydrogen 3.103 N/A ALA 131.A N LEU 127.A O no hydrogen 2.919 N/A VAL 132.A N SER 128.A O no hydrogen 3.130 N/A ALA 133.A N ASN 129.A O no hydrogen 3.072 N/A MET 134.A N ILE 130.A O no hydrogen 2.990 N/A ARG 135.A N ALA 131.A O no hydrogen 3.074 N/A MET 136.A N VAL 132.A O no hydrogen 2.910 N/A GLN 137.A N ALA 133.A O no hydrogen 3.021 N/A ALA 139.A N GLN 137.A OE1 no hydrogen 2.997 N/A ILE 140.A N GLN 137.A O no hydrogen 3.148 N/A LEU 141.A N PRO 138.A O no hydrogen 3.024 N/A LYS 143.A N ILE 140.A O no hydrogen 3.062 N/A LYS 143.A NZ MET 113.A O no hydrogen 3.428 N/A LYS 143.A NZ SER 115.A O no hydrogen 2.417 N/A ILE 144.A N LEU 141.A O no hydrogen 3.258 N/A ARG 145.A N ILE 119.A O no hydrogen 3.008 N/A ILE 147.A N PRO 183.A O no hydrogen 2.809 N/A VAL 148.A N LEU 121.A O no hydrogen 3.076 N/A LEU 149.A N VAL 185.A O no hydrogen 2.898 N/A MET 150.A N PRO 123.A O no hydrogen 3.013 N/A GLY 151.A N MET 187.A O no hydrogen 3.101 N/A GLY 152.A N GLU 164.A OE1 no hydrogen 2.871 N/A ALA 153.A N THR 273.A OG1 no hydrogen 3.076 N/A TYR 154.A N ASP 190.A OD2 no hydrogen 2.901 N/A GLY 155.A N ASP 190.A OD1 no hydrogen 2.824 N/A GLY 157.A N PRO 161.A O no hydrogen 3.035 N/A ASN 158.A N ALA 163.A O no hydrogen 3.095 N/A PHE 159.A N ASN 158.A OD1 no hydrogen 2.592 N/A THR 160.A N ALA 163.A O no hydrogen 3.347 N/A SER 162.A N THR 160.A OG1 no hydrogen 2.995 N/A SER 162.A OG PRO 268.A O no hydrogen 2.691 N/A ALA 163.A N THR 160.A OG1 no hydrogen 2.916 N/A PHE 165.A N ASN 158.A OD1 no hydrogen 3.031 N/A ASN 166.A N GLU 164.A OE2 no hydrogen 2.924 N/A ASN 166.A ND2 MET 150.A O no hydrogen 2.877 N/A ILE 167.A N GLU 164.A OE1 no hydrogen 3.258 N/A PHE 168.A N GLU 164.A O no hydrogen 2.882 N/A ALA 169.A N PHE 165.A O no hydrogen 2.831 N/A ASP 170.A N ILE 167.A O no hydrogen 2.987 N/A ALA 173.A N ASP 170.A OD1 no hydrogen 3.047 N/A ALA 174.A N ASP 170.A O no hydrogen 3.125 N/A ARG 175.A N PRO 171.A O no hydrogen 2.938 N/A ARG 175.A NE VAL 262.A O no hydrogen 3.155 N/A ARG 175.A NH2 VAL 262.A O no hydrogen 2.935 N/A VAL 176.A N GLU 172.A O no hydrogen 3.138 N/A VAL 177.A N ALA 173.A O no hydrogen 3.164 N/A PHE 178.A N ALA 174.A O no hydrogen 2.874 N/A THR 179.A N ARG 175.A O no hydrogen 3.079 N/A THR 179.A N VAL 176.A O no hydrogen 3.303 N/A THR 179.A OG1 ARG 175.A O no hydrogen 2.771 N/A THR 179.A OG1 VAL 176.A O no hydrogen 3.182 N/A SER 180.A N VAL 177.A O no hydrogen 3.131 N/A SER 180.A OG VAL 177.A O no hydrogen 2.734 N/A VAL 182.A N SER 180.A OG no hydrogen 3.294 N/A VAL 185.A N ILE 147.A O no hydrogen 2.742 N/A MET 186.A N LYS 288.A O no hydrogen 2.785 N/A MET 187.A N LEU 149.A O no hydrogen 2.887 N/A LEU 189.A N GLY 152.A O no hydrogen 2.864 N/A LEU 191.A N GLY 188.A O no hydrogen 3.034 N/A THR 192.A N GLY 188.A O no hydrogen 2.901 N/A THR 192.A OG1 GLY 188.A O no hydrogen 3.153 N/A THR 192.A OG1 HIS 239.A ND1 no hydrogen 2.826 N/A ASN 193.A N LEU 189.A O no hydrogen 2.892 N/A GLN 194.A N LEU 191.A O no hydrogen 2.989 N/A GLN 194.A NE2 ASP 190.A O no hydrogen 2.845 N/A GLN 194.A NE2 ILE 291.A O no hydrogen 2.894 N/A THR 195.A N THR 192.A O no hydrogen 2.950 N/A THR 195.A OG1 THR 192.A O no hydrogen 2.657 N/A CYS 197.A N GLY 236.A O no hydrogen 2.922 N/A THR 198.A OG1 ASP 200.A OD1 no hydrogen 2.558 N/A VAL 201.A N THR 198.A O no hydrogen 3.034 N/A ILE 202.A N THR 198.A O no hydrogen 3.226 N/A ALA 203.A N PRO 199.A O no hydrogen 2.913 N/A ARG 204.A N ASP 200.A O no hydrogen 3.039 N/A ARG 204.A NE GLU 303.A OE1 no hydrogen 2.969 N/A ARG 204.A NH2 GLU 303.A OE1 no hydrogen 3.067 N/A MET 205.A N VAL 201.A O no hydrogen 3.234 N/A GLU 206.A N ILE 202.A O no hydrogen 2.895 N/A ARG 207.A N ALA 203.A O no hydrogen 2.791 N/A ALA 208.A N ARG 204.A O no hydrogen 3.090 N/A GLY 209.A N MET 205.A O no hydrogen 2.952 N/A GLU 214.A N GLY 210.A O no hydrogen 3.025 N/A LEU 215.A N PRO 211.A O no hydrogen 3.145 N/A PHE 216.A N ALA 212.A O no hydrogen 2.849 N/A SER 217.A N GLY 213.A O no hydrogen 3.134 N/A SER 217.A OG GLU 206.A OE2 no hydrogen 2.499 N/A ASP 218.A N GLU 214.A O no hydrogen 2.886 N/A ILE 219.A N LEU 215.A O no hydrogen 2.876 N/A MET 220.A N PHE 216.A O no hydrogen 2.861 N/A ASN 221.A N SER 217.A O no hydrogen 3.149 N/A ASN 221.A ND2 SER 217.A O no hydrogen 3.123 N/A PHE 222.A N ILE 219.A O no hydrogen 3.253 N/A THR 223.A OG1 MET 220.A O no hydrogen 3.564 N/A THR 226.A OG1 ILE 81.A O no hydrogen 2.913 N/A THR 226.A OG1 THR 223.A O no hydrogen 3.428 N/A GLN 227.A N THR 223.A O no hydrogen 2.830 N/A PHE 228.A N LEU 224.A O no hydrogen 3.223 N/A GLU 229.A N LYS 225.A O no hydrogen 2.924 N/A ASN 230.A N THR 226.A O no hydrogen 3.036 N/A ASN 230.A ND2 ASN 80.A O no hydrogen 3.505 N/A ASN 230.A ND2 THR 226.A O no hydrogen 2.774 N/A TYR 231.A N GLN 227.A O no hydrogen 2.991 N/A GLY 232.A N PHE 228.A O no hydrogen 2.671 N/A VAL 238.A N THR 195.A O no hydrogen 3.095 N/A VAL 238.A N THR 195.A OG1 no hydrogen 2.885 N/A HIS 239.A ND1 THR 192.A OG1 no hydrogen 2.826 N/A ASP 240.A N ASP 15.A OD2 no hydrogen 2.815 N/A THR 242.A N HIS 239.A O no hydrogen 3.146 N/A THR 242.A OG1 HIS 239.A O no hydrogen 2.845 N/A CYS 243.A N ASP 240.A O no hydrogen 3.351 N/A CYS 243.A SG VAL 148.A O no hydrogen 3.813 N/A GLY 245.A N ALA 241.A O no hydrogen 3.050 N/A TYR 246.A N THR 242.A O no hydrogen 2.812 N/A LEU 247.A N CYS 243.A O no hydrogen 3.280 N/A ILE 248.A N ILE 244.A O no hydrogen 3.018 N/A ASN 249.A N GLY 245.A O no hydrogen 2.938 N/A ASP 251.A N ASN 249.A OD1 no hydrogen 3.093 N/A GLY 252.A N ASN 249.A O no hydrogen 3.181 N/A ILE 253.A N PRO 250.A O no hydrogen 3.101 N/A LYS 254.A N THR 292.A O no hydrogen 2.859 N/A LYS 254.A NZ.B THR 255.A O no hydrogen 2.602 N/A GLN 256.A N VAL 289.A O no hydrogen 2.804 N/A GLN 256.A NE2 GLU 277.A O no hydrogen 2.799 N/A MET 258.A N THR 287.A O no hydrogen 2.936 N/A TYR 259.A OH GLU 261.A OE1 no hydrogen 3.100 N/A VAL 260.A N ASN 286.A OD1 no hydrogen 2.924 N/A GLU 261.A N VAL 274.A O no hydrogen 2.953 N/A ASP 263.A N ARG 272.A O no hydrogen 2.942 N/A ASN 265.A N ASP 263.A OD1 no hydrogen 2.961 N/A ASN 265.A ND2 ASP 263.A OD1 no hydrogen 3.034 N/A CYS 269.A SG SER 162.A OG no hydrogen 3.481 N/A TYR 270.A N GLY 267.A O no hydrogen 3.266 N/A TYR 270.A OH GLU 172.A OE1 no hydrogen 3.224 N/A TYR 270.A OH GLU 172.A OE2 no hydrogen 2.692 N/A GLY 271.A N ASP 263.A O no hydrogen 2.833 N/A ARG 272.A N CYS 269.A O no hydrogen 2.976 N/A ARG 272.A NH1 GLY 155.A O no hydrogen 2.949 N/A ARG 272.A NH1 SER 162.A O no hydrogen 2.864 N/A ARG 272.A NH2 GLY 155.A O no hydrogen 3.224 N/A THR 273.A OG1 ALA 153.A O no hydrogen 2.866 N/A VAL 274.A N GLU 261.A O no hydrogen 2.770 N/A CYS 275.A SG THR 273.A O no hydrogen 3.598 N/A ASP 276.A N TYR 259.A O no hydrogen 3.019 N/A GLU 277.A N CYS 275.A O no hydrogen 2.939 N/A GLY 279.A N ASP 276.A O no hydrogen 3.192 N/A VAL 280.A N ASP 276.A OD1 no hydrogen 2.923 N/A LEU 281.A N ASP 276.A OD2 no hydrogen 2.870 N/A GLY 282.A N GLY 279.A O no hydrogen 3.436 N/A ASN 286.A N MET 258.A O no hydrogen 2.880 N/A ASN 286.A ND2 VAL 260.A O no hydrogen 3.060 N/A THR 287.A N MET 258.A O no hydrogen 3.205 N/A THR 287.A OG1 ASN 286.A OD1 no hydrogen 2.823 N/A LYS 288.A N LEU 184.A O no hydrogen 2.944 N/A VAL 289.A N GLN 256.A O no hydrogen 2.839 N/A GLY 290.A N MET 186.A O no hydrogen 2.914 N/A ILE 291.A N LYS 254.A O no hydrogen 2.802 N/A THR 292.A N LYS 254.A O no hydrogen 3.454 N/A ILE 293.A N GLN 194.A OE1 no hydrogen 3.222 N/A ASP 294.A N GLY 252.A O no hydrogen 2.969 N/A TRP 297.A N ASP 294.A OD1 no hydrogen 2.952 N/A PHE 298.A N ASP 294.A O no hydrogen 2.977 N/A TRP 299.A N THR 295.A O no hydrogen 2.974 N/A GLY 300.A N ASP 296.A O no hydrogen 3.242 N/A LEU 301.A N TRP 297.A O no hydrogen 3.094 N/A VAL 302.A N PHE 298.A O no hydrogen 3.031 N/A GLU 303.A N TRP 299.A O no hydrogen 3.044 N/A GLU 304.A N GLY 300.A O no hydrogen 2.924 N/A CYS 305.A N LEU 301.A O no hydrogen 2.993 N/A CYS 305.A SG LEU 301.A O no hydrogen 3.277 N/A VAL 306.A N VAL 302.A O no hydrogen 2.840 N/A ARG 307.A N GLU 303.A O no hydrogen 2.688 N/A ARG 307.A NE GLU 303.A OE2 no hydrogen 2.786 N/A ARG 307.A NH2 GLU 303.A OE2 no hydrogen 3.103 N/A GLY 308.A N GLU 304.A O no hydrogen 3.068 N/A TYR 309.A N VAL 306.A O no hydrogen 3.087 N/A TYR 309.A OH MET 21.A O no hydrogen 2.532 N/A ILE 310.A N ARG 307.A O no hydrogen 3.173 N/A