Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3mpu_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A N ARG 306.A O no hydrogen 2.898 N/A ASN 2.A ND2 LEU 302.A O no hydrogen 2.911 N/A ASN 2.A ND2 ARG 306.A O no hydrogen 2.750 N/A LEU 4.A N ASN 2.A OD1 no hydrogen 2.823 N/A TYR 5.A N ASN 2.A O no hydrogen 3.111 N/A GLN 6.A N VAL 303.A O no hydrogen 2.770 N/A LYS 7.A N LEU 4.A O no hydrogen 3.185 N/A ILE 9.A N VAL 124.A O no hydrogen 2.846 N/A ILE 12.A N GLN 133.A OE1 no hydrogen 2.675 N/A ASP 14.A N SER 11.A O no hydrogen 2.741 N/A LEU 15.A N ILE 12.A O no hydrogen 2.615 N/A SER 16.A N ASP 19.A OD2 no hydrogen 3.059 N/A ARG 17.A NH1 LYS 178.A O no hydrogen 3.002 N/A ASP 19.A N SER 16.A OG no hydrogen 3.007 N/A LEU 20.A N SER 16.A O no hydrogen 3.172 N/A ASN 21.A N ARG 17.A O no hydrogen 2.939 N/A LEU 22.A N ASP 18.A O no hydrogen 3.006 N/A VAL 23.A N ASP 19.A O no hydrogen 3.048 N/A LEU 24.A N LEU 20.A O no hydrogen 3.047 N/A ALA 25.A N ASN 21.A O no hydrogen 2.866 N/A THR 26.A N LEU 22.A O no hydrogen 2.993 N/A THR 26.A OG1 LEU 22.A O no hydrogen 2.751 N/A ALA 27.A N VAL 23.A O no hydrogen 2.648 N/A ALA 28.A N LEU 24.A O no hydrogen 3.208 N/A LYS 29.A N ALA 25.A O no hydrogen 3.152 N/A LYS 29.A NZ LEU 310.A O no hydrogen 3.007 N/A LEU 30.A N THR 26.A O no hydrogen 3.303 N/A LEU 30.A N ALA 27.A O no hydrogen 2.464 N/A LYS 31.A N ALA 27.A O no hydrogen 3.295 N/A ALA 32.A N ALA 28.A O no hydrogen 2.699 N/A ASN 33.A N LYS 29.A O no hydrogen 2.840 N/A LEU 39.A N LEU 66.A O no hydrogen 2.788 N/A LYS 40.A N GLU 37.A O no hydrogen 3.243 N/A LYS 42.A N LEU 39.A O no hydrogen 3.149 N/A VAL 43.A N ASP 100.A OD2 no hydrogen 2.879 N/A ILE 44.A N SER 69.A O no hydrogen 2.862 N/A ALA 45.A N ALA 101.A O no hydrogen 3.041 N/A SER 46.A N VAL 71.A O no hydrogen 2.822 N/A SER 46.A OG GLU 60.A OE2 no hydrogen 2.727 N/A ALA 47.A N VAL 103.A O no hydrogen 2.787 N/A PHE 48.A N PHE 73.A O no hydrogen 2.986 N/A PHE 49.A N ARG 105.A O no hydrogen 2.986 N/A ARG 56.A N SER 52.A OG no hydrogen 2.719 N/A ARG 56.A NH1 GLU 60.A OE2 no hydrogen 2.834 N/A LEU 57.A N THR 53.A O no hydrogen 2.888 N/A SER 58.A N ARG 54.A O no hydrogen 2.917 N/A SER 58.A OG ARG 54.A O no hydrogen 2.816 N/A SER 58.A OG THR 55.A O no hydrogen 3.161 N/A PHE 59.A N THR 55.A O no hydrogen 3.133 N/A GLU 60.A N ARG 56.A O no hydrogen 2.981 N/A THR 61.A N LEU 57.A O no hydrogen 2.920 N/A THR 61.A OG1 LEU 57.A O no hydrogen 2.649 N/A SER 62.A N SER 58.A O no hydrogen 2.815 N/A SER 62.A OG SER 58.A O no hydrogen 2.789 N/A SER 62.A OG ILE 293.A O no hydrogen 3.158 N/A MET 63.A N PHE 59.A O no hydrogen 2.862 N/A HIS 64.A N GLU 60.A O no hydrogen 3.056 N/A ARG 65.A N THR 61.A O no hydrogen 2.948 N/A LEU 66.A N SER 62.A O no hydrogen 3.077 N/A LEU 66.A N MET 63.A O no hydrogen 3.231 N/A GLY 67.A N HIS 64.A O no hydrogen 2.693 N/A ALA 68.A N MET 63.A O no hydrogen 2.892 N/A SER 69.A N LYS 42.A O no hydrogen 2.823 N/A VAL 71.A N ILE 44.A O no hydrogen 3.099 N/A PHE 73.A N SER 46.A O no hydrogen 3.062 N/A SER 76.A OG PHE 49.A O no hydrogen 3.275 N/A THR 79.A N SER 76.A O no hydrogen 3.287 N/A THR 79.A OG1 SER 76.A O no hydrogen 2.764 N/A GLY 82.A N THR 79.A OG1 no hydrogen 3.425 N/A LYS 83.A N THR 79.A O no hydrogen 3.455 N/A LYS 84.A N SER 80.A O no hydrogen 2.632 N/A ASP 90.A N THR 87.A OG1 no hydrogen 3.008 N/A THR 91.A N THR 87.A O no hydrogen 3.117 N/A THR 91.A OG1 GLU 86.A OE1 no hydrogen 3.381 N/A THR 91.A OG1 THR 87.A O no hydrogen 2.876 N/A ILE 92.A N LEU 88.A O no hydrogen 2.669 N/A SER 93.A N ALA 89.A O no hydrogen 2.508 N/A SER 93.A OG ALA 89.A O no hydrogen 3.143 N/A VAL 94.A N ASP 90.A O no hydrogen 3.121 N/A ILE 95.A N THR 91.A O no hydrogen 3.383 N/A SER 96.A OG ILE 92.A O no hydrogen 3.256 N/A SER 96.A OG SER 119.A O no hydrogen 3.232 N/A THR 97.A N VAL 94.A O no hydrogen 2.771 N/A THR 97.A OG1 VAL 94.A O no hydrogen 3.143 N/A TYR 98.A N ILE 95.A O no hydrogen 2.717 N/A VAL 99.A N ILE 95.A O no hydrogen 3.151 N/A ASP 100.A N VAL 43.A O no hydrogen 2.734 N/A ILE 102.A N PRO 123.A O no hydrogen 2.885 N/A VAL 103.A N ALA 45.A O no hydrogen 2.960 N/A MET 104.A N LEU 125.A O no hydrogen 3.109 N/A ARG 105.A N ALA 47.A O no hydrogen 3.306 N/A ARG 105.A NE ALA 127.A O no hydrogen 2.951 N/A ARG 105.A NH1 ALA 51.A O no hydrogen 2.873 N/A ARG 105.A NH2 ALA 127.A O no hydrogen 3.172 N/A HIS 106.A N GLY 128.A O no hydrogen 2.871 N/A GLN 108.A N HIS 106.A ND1 no hydrogen 3.063 N/A GLY 110.A N ASP 129.A OD2 no hydrogen 2.910 N/A ALA 111.A N GLN 108.A O no hydrogen 3.352 N/A ARG 113.A NH1 ASP 14.A OD2 no hydrogen 3.377 N/A LEU 114.A N GLY 110.A O no hydrogen 2.977 N/A ALA 115.A N ALA 111.A O no hydrogen 3.027 N/A THR 116.A N ALA 112.A O no hydrogen 3.310 N/A THR 116.A N ARG 113.A O no hydrogen 3.079 N/A THR 116.A OG1 ARG 113.A O no hydrogen 2.606 N/A GLU 117.A N LEU 114.A O no hydrogen 3.064 N/A PHE 118.A N ALA 115.A O no hydrogen 3.031 N/A SER 119.A N THR 116.A O no hydrogen 3.484 N/A SER 119.A OG ALA 115.A O no hydrogen 3.097 N/A SER 119.A OG THR 116.A O no hydrogen 3.089 N/A SER 119.A OG VAL 122.A O no hydrogen 3.163 N/A VAL 122.A N SER 119.A O no hydrogen 3.227 N/A VAL 124.A N HIS 8.A ND1 no hydrogen 3.037 N/A LEU 125.A N ILE 102.A O no hydrogen 2.737 N/A ASN 126.A N ILE 9.A O no hydrogen 2.832 N/A ASN 126.A ND2 ILE 10.A O no hydrogen 2.972 N/A ASN 126.A ND2 ASP 129.A OD1 no hydrogen 3.005 N/A ALA 127.A N MET 104.A O no hydrogen 2.768 N/A GLY 128.A N ASN 126.A OD1 no hydrogen 2.609 N/A GLY 130.A N HIS 106.A O no hydrogen 2.892 N/A SER 131.A N GLU 109.A OE2 no hydrogen 2.912 N/A SER 131.A OG GLU 109.A OE2 no hydrogen 2.909 N/A ASN 132.A N ASP 129.A O no hydrogen 2.976 N/A ASN 132.A ND2 ASP 129.A OD1 no hydrogen 3.490 N/A ASN 132.A ND2 ASP 129.A OD2 no hydrogen 2.840 N/A GLN 133.A N ASP 129.A OD1 no hydrogen 2.874 N/A GLN 133.A NE2 GLN 174.A OE1 no hydrogen 2.975 N/A HIS 134.A N SER 171.A OG no hydrogen 2.770 N/A GLN 137.A NE2 ASP 141.A OD1 no hydrogen 2.895 N/A THR 138.A N HIS 134.A O no hydrogen 3.190 N/A LEU 139.A N PRO 135.A O no hydrogen 2.980 N/A LEU 140.A N THR 136.A O no hydrogen 3.151 N/A ASP 141.A N GLN 137.A O no hydrogen 2.700 N/A LEU 142.A N THR 138.A O no hydrogen 2.720 N/A PHE 143.A N LEU 139.A O no hydrogen 3.064 N/A THR 144.A N LEU 140.A O no hydrogen 2.672 N/A THR 144.A OG1 LEU 140.A O no hydrogen 3.136 N/A ILE 145.A N ASP 141.A O no hydrogen 2.840 N/A GLN 146.A N LEU 142.A O no hydrogen 2.787 N/A GLU 147.A N PHE 143.A O no hydrogen 2.809 N/A THR 148.A N THR 144.A O no hydrogen 2.983 N/A THR 148.A OG1 THR 144.A O no hydrogen 3.024 N/A THR 148.A OG1 ILE 145.A O no hydrogen 3.556 N/A GLN 149.A N ILE 145.A O no hydrogen 2.822 N/A GLN 149.A N GLN 146.A O no hydrogen 3.221 N/A GLN 149.A NE2 ASN 260.A O no hydrogen 2.912 N/A GLY 150.A N GLN 146.A O no hydrogen 2.889 N/A ARG 151.A NE ASP 153.A O no hydrogen 2.952 N/A ARG 151.A NE ASN 154.A O no hydrogen 3.230 N/A ARG 151.A NH2 ASN 154.A O no hydrogen 2.812 N/A ASN 154.A N ASP 180.A O no hydrogen 2.759 N/A ASN 154.A ND2 ASP 153.A OD1 no hydrogen 3.555 N/A LEU 155.A N ASN 182.A OD1 no hydrogen 2.637 N/A HIS 156.A N ASP 223.A OD2 no hydrogen 2.903 N/A VAL 157.A N ARG 183.A O no hydrogen 2.956 N/A ALA 158.A N ILE 224.A O no hydrogen 2.950 N/A MET 159.A N TYR 185.A O no hydrogen 2.848 N/A VAL 160.A N TYR 226.A O no hydrogen 3.164 N/A GLY 161.A N ILE 187.A O no hydrogen 2.738 N/A LEU 163.A N LEU 192.A O no hydrogen 2.881 N/A LYS 164.A N LEU 192.A O no hydrogen 2.873 N/A LYS 164.A NZ TYR 165.A OH no hydrogen 3.007 N/A LYS 164.A NZ GLU 239.A OE2 no hydrogen 2.921 N/A TYR 165.A N ASP 162.A OD1 no hydrogen 2.870 N/A TYR 165.A OH GLU 239.A OE1 no hydrogen 2.937 N/A TYR 165.A OH GLU 239.A OE2 no hydrogen 3.017 N/A VAL 169.A N GLY 166.A O no hydrogen 3.267 N/A HIS 170.A N GLY 166.A O no hydrogen 3.388 N/A HIS 170.A ND1 ASN 132.A O no hydrogen 2.903 N/A HIS 170.A NE2 LEU 163.A O no hydrogen 2.957 N/A SER 171.A N ARG 167.A O no hydrogen 3.219 N/A SER 171.A OG ARG 167.A O no hydrogen 2.897 N/A LEU 172.A N THR 168.A O no hydrogen 3.122 N/A THR 173.A N VAL 169.A O no hydrogen 2.885 N/A THR 173.A OG1 VAL 169.A O no hydrogen 2.829 N/A GLN 174.A N HIS 170.A O no hydrogen 3.215 N/A ALA 175.A N SER 171.A O no hydrogen 2.978 N/A LEU 176.A N LEU 172.A O no hydrogen 2.890 N/A ALA 177.A N THR 173.A O no hydrogen 3.026 N/A LYS 178.A N ALA 175.A O no hydrogen 2.999 N/A LYS 178.A NZ LEU 15.A O no hydrogen 2.673 N/A PHE 179.A N LEU 176.A O no hydrogen 2.889 N/A ASN 182.A ND2 LEU 152.A O no hydrogen 2.872 N/A ASN 182.A ND2 LEU 176.A O no hydrogen 3.169 N/A ARG 183.A N LEU 155.A O no hydrogen 2.836 N/A PHE 184.A N ALA 208.A O no hydrogen 3.045 N/A TYR 185.A N VAL 157.A O no hydrogen 2.928 N/A PHE 186.A N SER 210.A O no hydrogen 3.106 N/A ILE 187.A N MET 159.A O no hydrogen 2.835 N/A LEU 192.A N PRO 189.A O no hydrogen 2.918 N/A TYR 197.A OH HIS 170.A ND1 no hydrogen 3.236 N/A ILE 198.A N PRO 195.A O no hydrogen 3.245 N/A LEU 199.A N PRO 195.A O no hydrogen 3.455 N/A ASP 200.A N GLN 196.A O no hydrogen 2.861 N/A LEU 202.A N ILE 198.A O no hydrogen 2.929 N/A ASP 203.A N LEU 199.A O no hydrogen 2.914 N/A GLU 204.A N ASP 200.A O no hydrogen 3.116 N/A LYS 205.A N MET 201.A O no hydrogen 3.021 N/A GLY 206.A N ASP 203.A O no hydrogen 2.857 N/A ILE 207.A N LEU 202.A O no hydrogen 2.794 N/A TRP 209.A NE1 ASP 203.A OD1 no hydrogen 3.129 N/A SER 210.A N PHE 184.A O no hydrogen 3.256 N/A SER 210.A OG HIS 212.A NE2 no hydrogen 2.440 N/A HIS 212.A N PHE 186.A O no hydrogen 3.241 N/A HIS 212.A ND1 GLU 217.A OE2 no hydrogen 2.749 N/A HIS 212.A NE2 SER 210.A OG no hydrogen 2.440 N/A SER 213.A N GLU 217.A OE1 no hydrogen 2.886 N/A SER 213.A OG GLU 217.A OE1 no hydrogen 3.106 N/A GLU 217.A N SER 214.A OG no hydrogen 3.159 N/A VAL 218.A N ILE 215.A O no hydrogen 2.979 N/A MET 219.A N ILE 215.A O no hydrogen 2.856 N/A MET 219.A N GLU 216.A O no hydrogen 2.940 N/A GLU 221.A N VAL 218.A O no hydrogen 2.679 N/A VAL 222.A N MET 219.A O no hydrogen 3.003 N/A ASP 223.A N HIS 156.A O no hydrogen 2.813 N/A ILE 224.A N HIS 156.A O no hydrogen 3.372 N/A LEU 225.A N LYS 262.A O no hydrogen 3.004 N/A TYR 226.A N ALA 158.A O no hydrogen 2.846 N/A TYR 226.A OH ASP 141.A OD1 no hydrogen 3.279 N/A TYR 226.A OH ASP 141.A OD2 no hydrogen 2.749 N/A MET 227.A N LEU 264.A O no hydrogen 2.991 N/A THR 228.A N VAL 160.A O no hydrogen 2.966 N/A THR 228.A OG1 VAL 160.A O no hydrogen 2.873 N/A ARG 229.A NH2 GLN 231.A OE1 no hydrogen 3.396 N/A ARG 229.A NH2 GLU 233.A OE2 no hydrogen 2.899 N/A GLN 231.A N ASP 162.A OD2 no hydrogen 3.011 N/A LYS 232.A N VAL 230.A O no hydrogen 2.696 N/A GLU 233.A N GLU 233.A OE2 no hydrogen 2.738 N/A ARG 234.A N GLN 231.A O no hydrogen 2.738 N/A ARG 234.A NH1 GLU 50.A OE1 no hydrogen 2.817 N/A ARG 234.A NH1 GLU 50.A OE2 no hydrogen 3.512 N/A ARG 234.A NH2 GLU 50.A OE1 no hydrogen 2.767 N/A LEU 235.A N LYS 232.A O no hydrogen 3.251 N/A ASP 236.A N GLU 239.A OE1 no hydrogen 2.589 N/A TYR 240.A N PRO 237.A O no hydrogen 3.261 N/A ASN 242.A N GLU 239.A O no hydrogen 2.774 N/A ASN 242.A ND2 GLU 239.A O no hydrogen 2.918 N/A VAL 243.A N TYR 240.A O no hydrogen 3.485 N/A LYS 244.A NZ ALA 245.A O no hydrogen 3.202 N/A LYS 244.A NZ ASP 271.A OD2 no hydrogen 3.112 N/A LEU 249.A N GLU 272.A O no hydrogen 2.912 N/A ARG 250.A N ASP 253.A OD2 no hydrogen 2.963 N/A ALA 251.A N ASP 276.A OD1 no hydrogen 3.028 N/A SER 252.A OG ASP 253.A OD1 no hydrogen 3.385 N/A ASP 253.A N ARG 250.A O no hydrogen 3.118 N/A LEU 254.A N ALA 251.A O no hydrogen 3.094 N/A HIS 255.A ND1 ASN 256.A OD1 no hydrogen 3.211 N/A ASN 256.A ND2 GLU 216.A OE2 no hydrogen 2.966 N/A LYS 258.A NZ ASP 223.A OD1 no hydrogen 3.053 N/A ASN 260.A ND2 GLN 149.A OE1 no hydrogen 2.598 N/A ASN 260.A ND2 ASP 223.A OD1 no hydrogen 3.079 N/A MET 261.A N LYS 258.A O no hydrogen 3.310 N/A LYS 262.A N ASP 223.A O no hydrogen 3.143 N/A VAL 263.A N HIS 282.A O no hydrogen 2.769 N/A LEU 264.A N LEU 225.A O no hydrogen 2.886 N/A HIS 265.A N GLN 288.A OE1 no hydrogen 2.782 N/A HIS 265.A NE2 GLU 272.A OE2 no hydrogen 2.620 N/A LEU 267.A N HIS 265.A ND1 no hydrogen 2.781 N/A ARG 269.A NH1 ASP 278.A OD1 no hydrogen 2.773 N/A ARG 269.A NH2 ASP 278.A OD1 no hydrogen 3.503 N/A ARG 269.A NH2 ASP 278.A OD2 no hydrogen 3.116 N/A VAL 270.A N GLU 272.A OE1 no hydrogen 3.236 N/A VAL 270.A N GLU 272.A OE2 no hydrogen 3.207 N/A GLU 272.A N GLU 272.A OE1 no hydrogen 2.607 N/A ALA 274.A N LEU 249.A O no hydrogen 3.083 N/A VAL 277.A N ALA 274.A O no hydrogen 3.007 N/A ASP 278.A N THR 275.A O no hydrogen 3.212 N/A THR 280.A N VAL 277.A O no hydrogen 2.988 N/A THR 280.A OG1 VAL 277.A O no hydrogen 2.927 N/A HIS 282.A N THR 280.A OG1 no hydrogen 3.236 N/A HIS 282.A ND1 MET 261.A O no hydrogen 2.626 N/A ALA 283.A N THR 280.A OG1 no hydrogen 3.364 N/A TRP 284.A N VAL 263.A O no hydrogen 3.100 N/A TRP 284.A NE1 GLU 147.A OE1 no hydrogen 2.942 N/A TYR 285.A OH ASP 278.A OD1 no hydrogen 2.915 N/A GLN 287.A N GLN 287.A OE1 no hydrogen 2.616 N/A GLN 288.A N TRP 284.A O no hydrogen 2.741 N/A GLN 288.A NE2 ASP 141.A OD1 no hydrogen 2.900 N/A ALA 289.A N TYR 285.A O no hydrogen 2.681 N/A GLY 290.A N PHE 286.A O no hydrogen 2.909 N/A ASN 291.A N GLN 287.A O no hydrogen 3.179 N/A ASN 291.A N GLN 288.A O no hydrogen 2.867 N/A ASN 291.A ND2 THR 144.A OG1 no hydrogen 3.031 N/A ASN 291.A ND2 GLU 147.A OE1 no hydrogen 3.014 N/A GLY 292.A N ALA 289.A O no hydrogen 2.775 N/A ILE 293.A N GLY 290.A O no hydrogen 3.357 N/A PHE 294.A N ASN 291.A O no hydrogen 3.190 N/A ALA 295.A N ASN 291.A O no hydrogen 3.137 N/A ARG 296.A N GLY 292.A O no hydrogen 3.069 N/A ARG 296.A NE THR 136.A OG1 no hydrogen 3.362 N/A ARG 296.A NH2 THR 136.A OG1 no hydrogen 3.213 N/A GLN 297.A N ILE 293.A O no hydrogen 2.939 N/A ALA 298.A N PHE 294.A O no hydrogen 3.083 N/A LEU 299.A N ALA 295.A O no hydrogen 2.972 N/A LEU 300.A N ARG 296.A O no hydrogen 2.948 N/A ALA 301.A N GLN 297.A O no hydrogen 2.910 N/A LEU 302.A N ALA 298.A O no hydrogen 2.843 N/A VAL 303.A N LEU 299.A O no hydrogen 2.990 N/A LEU 304.A N LEU 300.A O no hydrogen 3.053 N/A ASN 305.A N ALA 301.A O no hydrogen 2.913 N/A ASN 305.A ND2 ASP 307.A O no hydrogen 3.049 N/A