Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3nnx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 5.A N VAL 16.A O no hydrogen 2.769 N/A TYR 5.A OH TYR 20.A O no hydrogen 2.608 N/A LEU 9.A N THR 12.A O no hydrogen 2.872 N/A LYS 11.A N LEU 9.A O no hydrogen 2.514 N/A THR 12.A N LEU 9.A O no hydrogen 2.950 N/A TRP 14.A N GLN 7.A O no hydrogen 2.659 N/A GLU 15.A N TYR 99.A OH no hydrogen 2.903 N/A VAL 16.A N TYR 5.A O no hydrogen 3.256 N/A GLU 18.A N THR 3.A O no hydrogen 2.826 N/A ARG 19.A NE ASP 39.A OD1 no hydrogen 2.537 N/A ARG 19.A NH2 ASP 39.A OD1 no hydrogen 3.195 N/A ARG 19.A NH2 ASP 39.A OD2 no hydrogen 2.786 N/A TYR 20.A N PRO 17.A O no hydrogen 3.125 N/A TYR 20.A OH ASP 84.A OD2 no hydrogen 2.624 N/A GLN 21.A N PHE 38.A O no hydrogen 2.660 N/A SER 24.A N ALA 36.A O no hydrogen 2.719 N/A VAL 26.A N VAL 34.A O no hydrogen 2.823 N/A GLY 27.A N VAL 34.A O no hydrogen 3.242 N/A GLY 29.A N GLY 32.A O no hydrogen 2.902 N/A TYR 31.A N LEU 163.A O no hydrogen 2.849 N/A GLY 32.A N GLY 29.A O no hydrogen 3.300 N/A SER 33.A N LYS 50.A O no hydrogen 2.876 N/A VAL 34.A N GLY 27.A O no hydrogen 2.787 N/A CYS 35.A N VAL 48.A O no hydrogen 3.023 N/A ALA 36.A N SER 24.A O no hydrogen 2.812 N/A ALA 37.A N VAL 46.A O no hydrogen 2.783 N/A PHE 38.A N GLN 21.A O no hydrogen 2.787 N/A ASP 39.A N LEU 44.A O no hydrogen 3.023 N/A THR 40.A N ARG 19.A O no hydrogen 2.607 N/A THR 40.A OG1 ARG 19.A O no hydrogen 3.053 N/A LYS 41.A N ASP 39.A OD1 no hydrogen 3.354 N/A THR 42.A N ASP 39.A O no hydrogen 3.423 N/A THR 42.A OG1 ASP 39.A O no hydrogen 3.512 N/A THR 42.A OG1 ASP 39.A OD2 no hydrogen 2.782 N/A GLY 43.A N ASP 39.A O no hydrogen 2.822 N/A LEU 44.A N THR 42.A OG1 no hydrogen 3.195 N/A ARG 45.A NE ALA 37.A O no hydrogen 3.334 N/A VAL 46.A N ALA 37.A O no hydrogen 2.827 N/A ALA 47.A N THR 102.A O no hydrogen 2.736 N/A VAL 48.A N CYS 35.A O no hydrogen 2.807 N/A LYS 49.A N LEU 100.A O no hydrogen 2.649 N/A LYS 49.A NZ GLU 67.A OE1 no hydrogen 3.361 N/A LYS 49.A NZ GLU 67.A OE2 no hydrogen 2.887 N/A LYS 49.A NZ PHE 161.A O no hydrogen 2.690 N/A LYS 50.A N SER 33.A O no hydrogen 2.853 N/A LYS 50.A NZ ILE 13.A O no hydrogen 2.634 N/A LEU 51.A N VAL 98.A O no hydrogen 3.022 N/A SER 52.A N TYR 31.A O no hydrogen 3.242 N/A SER 52.A OG ALA 30.A O no hydrogen 3.197 N/A GLN 56.A N ARG 53.A O no hydrogen 3.260 N/A GLN 56.A NE2 ARG 53.A O no hydrogen 3.209 N/A HIS 60.A N SER 57.A OG no hydrogen 3.182 N/A ALA 61.A N SER 57.A O no hydrogen 3.181 N/A LYS 62.A N ILE 58.A O no hydrogen 2.942 N/A LYS 62.A NZ GLU 312.A O no hydrogen 2.940 N/A LYS 62.A NZ ARG 314.A O no hydrogen 3.331 N/A ARG 63.A N ILE 59.A O no hydrogen 3.086 N/A ARG 63.A NH1 GLY 162.A O no hydrogen 2.788 N/A ARG 63.A NH2 GLY 162.A O no hydrogen 3.318 N/A THR 64.A N HIS 60.A O no hydrogen 3.015 N/A THR 64.A OG1 PRO 54.A O no hydrogen 3.002 N/A THR 64.A OG1 HIS 60.A O no hydrogen 2.481 N/A TYR 65.A N ALA 61.A O no hydrogen 3.081 N/A ARG 66.A N LYS 62.A O no hydrogen 2.734 N/A ARG 66.A NE GLU 312.A OE2 no hydrogen 2.723 N/A ARG 66.A NH2 GLU 312.A OE1 no hydrogen 2.968 N/A GLU 67.A N ARG 63.A O no hydrogen 2.996 N/A LEU 68.A N THR 64.A O no hydrogen 3.044 N/A ARG 69.A N TYR 65.A O no hydrogen 2.916 N/A ARG 69.A NH1 TYR 65.A OH no hydrogen 2.851 N/A ARG 69.A NH2 ASP 308.A O no hydrogen 2.899 N/A LEU 70.A N ARG 66.A O no hydrogen 2.858 N/A LEU 71.A N GLU 67.A O no hydrogen 2.936 N/A LYS 72.A N LEU 68.A O no hydrogen 3.117 N/A LYS 72.A NZ GLU 328.A O no hydrogen 2.728 N/A LYS 72.A NZ GLU 328.A OE1 no hydrogen 2.754 N/A HIS 73.A N ARG 69.A O no hydrogen 3.009 N/A HIS 73.A NE2 ASP 305.A O no hydrogen 2.812 N/A MET 74.A N LEU 70.A O no hydrogen 3.066 N/A LYS 75.A N TYR 132.A OH no hydrogen 2.806 N/A ASN 78.A ND2 GLN 125.A OE1 no hydrogen 3.623 N/A ASN 78.A ND2 LEU 156.A O no hydrogen 3.050 N/A VAL 79.A N HIS 76.A O no hydrogen 3.299 N/A ILE 80.A N ILE 158.A O no hydrogen 2.818 N/A LEU 83.A N VAL 101.A O no hydrogen 3.016 N/A ASP 84.A N VAL 101.A O no hydrogen 3.348 N/A VAL 85.A N ASP 84.A OD1 no hydrogen 2.757 N/A PHE 86.A N TYR 99.A O no hydrogen 2.973 N/A THR 87.A OG1 ASP 97.A O no hydrogen 3.140 N/A ARG 90.A N GLU 94.A OE2 no hydrogen 2.475 N/A SER 91.A OG GLU 94.A OE2 no hydrogen 3.306 N/A GLU 94.A N SER 91.A O no hydrogen 2.990 N/A PHE 95.A N SER 91.A O no hydrogen 2.877 N/A TYR 99.A N PHE 86.A O no hydrogen 3.112 N/A LEU 100.A N LYS 49.A O no hydrogen 2.670 N/A VAL 101.A N ASP 84.A O no hydrogen 2.858 N/A THR 102.A N ALA 47.A O no hydrogen 2.898 N/A THR 102.A OG1 GLY 81.A O no hydrogen 2.881 N/A HIS 103.A ND1 ARG 45.A O no hydrogen 3.326 N/A LEU 104.A N THR 102.A O no hydrogen 2.970 N/A LEU 109.A N PRO 145.A O no hydrogen 2.993 N/A ASN 110.A N ASP 108.A OD1 no hydrogen 2.861 N/A ASN 111.A N ASP 108.A OD1 no hydrogen 3.217 N/A ILE 112.A N ASP 108.A O no hydrogen 3.095 N/A THR 115.A N HIS 118.A ND1 no hydrogen 2.939 N/A HIS 118.A N THR 115.A OG1 no hydrogen 3.141 N/A VAL 119.A N THR 115.A O no hydrogen 3.152 N/A GLN 120.A N ASP 116.A O no hydrogen 3.040 N/A PHE 121.A N ASP 117.A O no hydrogen 3.255 N/A LEU 122.A N HIS 118.A O no hydrogen 2.987 N/A ILE 123.A N VAL 119.A O no hydrogen 2.873 N/A TYR 124.A N GLN 120.A O no hydrogen 2.715 N/A TYR 124.A OH GLU 301.A OE2 no hydrogen 2.564 N/A GLN 125.A N PHE 121.A O no hydrogen 3.041 N/A GLN 125.A NE2 PHE 121.A O no hydrogen 3.039 N/A GLN 125.A NE2 CYS 154.A O no hydrogen 2.997 N/A ILE 126.A N LEU 122.A O no hydrogen 2.938 N/A LEU 127.A N ILE 123.A O no hydrogen 3.125 N/A ARG 128.A N TYR 124.A O no hydrogen 2.935 N/A ARG 128.A NE ASP 300.A O no hydrogen 2.921 N/A ARG 128.A NH1 GLU 77.A OE1 no hydrogen 3.126 N/A ARG 128.A NH1 ASN 78.A OD1 no hydrogen 2.932 N/A ARG 128.A NH2 ASP 300.A O no hydrogen 2.778 N/A GLY 129.A N GLN 125.A O no hydrogen 3.094 N/A LEU 130.A N ILE 126.A O no hydrogen 2.866 N/A LYS 131.A N LEU 127.A O no hydrogen 2.636 N/A LYS 131.A NZ GLU 301.A O no hydrogen 2.293 N/A TYR 132.A N ARG 128.A O no hydrogen 3.378 N/A ILE 133.A N GLY 129.A O no hydrogen 3.044 N/A HIS 134.A N LEU 130.A O no hydrogen 2.814 N/A HIS 134.A NE2 ASP 189.A OD2 no hydrogen 2.726 N/A SER 135.A N LYS 131.A O no hydrogen 2.916 N/A SER 135.A OG TYR 132.A O no hydrogen 2.416 N/A ALA 136.A N ILE 133.A O no hydrogen 2.930 N/A ASP 137.A N HIS 134.A O no hydrogen 3.014 N/A ILE 138.A N ILE 133.A O no hydrogen 3.388 N/A HIS 140.A N ASP 189.A OD2 no hydrogen 2.901 N/A HIS 140.A NE2 LEU 159.A O no hydrogen 2.598 N/A ARG 141.A N ASP 189.A OD1 no hydrogen 2.948 N/A ARG 141.A NH2 TYR 184.A OH no hydrogen 3.092 N/A ASP 142.A N HIS 140.A ND1 no hydrogen 3.121 N/A LYS 144.A NZ VAL 167.A O no hydrogen 3.009 N/A ASN 147.A N LYS 144.A O no hydrogen 3.014 N/A LEU 148.A N PRO 145.A O no hydrogen 3.373 N/A ALA 149.A N LYS 157.A O no hydrogen 2.947 N/A VAL 150.A N ALA 107.A O no hydrogen 2.862 N/A ASN 151.A N GLU 155.A O no hydrogen 3.022 N/A ASN 151.A ND2 GLU 155.A OE1 no hydrogen 2.640 N/A ASP 153.A N ASN 151.A OD1 no hydrogen 2.975 N/A CYS 154.A N ASN 151.A O no hydrogen 2.991 N/A GLU 155.A N ASN 151.A OD1 no hydrogen 2.962 N/A LEU 156.A N GLN 125.A OE1 no hydrogen 2.865 N/A LYS 157.A N ALA 149.A O no hydrogen 2.763 N/A LYS 157.A NZ VAL 79.A O no hydrogen 3.132 N/A ILE 158.A N ASN 78.A O no hydrogen 2.845 N/A LEU 159.A N ASN 147.A O no hydrogen 3.107 N/A ARG 170.A NE GLY 209.A O no hydrogen 3.033 N/A ARG 170.A NH2 GLY 209.A O no hydrogen 3.124 N/A TRP 171.A N ALA 168.A O no hydrogen 3.027 N/A TRP 171.A NE1 GLY 209.A O no hydrogen 2.812 N/A TYR 172.A N THR 169.A O no hydrogen 3.038 N/A TYR 172.A OH GLU 199.A OE1 no hydrogen 2.168 N/A ARG 173.A N ARG 170.A O no hydrogen 3.176 N/A ARG 173.A NE ARG 141.A O no hydrogen 3.187 N/A ARG 173.A NH2 ARG 141.A O no hydrogen 2.801 N/A GLU 176.A N GLU 176.A OE1 no hydrogen 2.916 N/A ILE 177.A N ALA 174.A O no hydrogen 3.268 N/A MET 178.A N ALA 174.A O no hydrogen 3.062 N/A LEU 179.A N PRO 175.A O no hydrogen 3.033 N/A TRP 181.A N GLU 176.A O no hydrogen 2.971 N/A GLN 186.A NE2 HIS 134.A O no hydrogen 3.033 N/A THR 187.A N ASN 185.A OD1 no hydrogen 2.996 N/A THR 187.A OG1 ASN 185.A OD1 no hydrogen 2.149 N/A THR 187.A OG1 SER 277.A O no hydrogen 3.467 N/A VAL 188.A N ASN 185.A O no hydrogen 3.420 N/A ASP 189.A N GLN 186.A O no hydrogen 3.222 N/A ILE 190.A N THR 187.A O no hydrogen 2.877 N/A TRP 191.A N THR 187.A O no hydrogen 3.136 N/A SER 192.A N VAL 188.A O no hydrogen 3.427 N/A SER 192.A OG TYR 172.A O no hydrogen 2.558 N/A SER 192.A OG VAL 188.A O no hydrogen 3.258 N/A VAL 193.A N ASP 189.A O no hydrogen 3.048 N/A GLY 194.A N ILE 190.A O no hydrogen 2.890 N/A CYS 195.A N TRP 191.A O no hydrogen 3.071 N/A CYS 195.A SG TRP 171.A O no hydrogen 3.852 N/A CYS 195.A SG TRP 191.A O no hydrogen 3.498 N/A ILE 196.A N SER 192.A O no hydrogen 3.020 N/A MET 197.A N VAL 193.A O no hydrogen 2.734 N/A ALA 198.A N GLY 194.A O no hydrogen 2.991 N/A GLU 199.A N CYS 195.A O no hydrogen 3.173 N/A LEU 200.A N ILE 196.A O no hydrogen 2.914 N/A LEU 201.A N MET 197.A O no hydrogen 3.230 N/A LEU 201.A N ALA 198.A O no hydrogen 3.237 N/A THR 202.A N ALA 198.A O no hydrogen 2.943 N/A THR 202.A OG1 ALA 198.A O no hydrogen 3.195 N/A GLY 203.A N GLU 199.A O no hydrogen 2.633 N/A ARG 204.A N THR 202.A OG1 no hydrogen 3.044 N/A GLY 209.A N PHE 207.A O no hydrogen 2.860 N/A THR 210.A N ASP 214.A OD2 no hydrogen 2.810 N/A THR 210.A OG1 ASP 211.A OD2 no hydrogen 3.515 N/A THR 210.A OG1 ASP 214.A OD2 no hydrogen 2.983 N/A ASP 214.A N ASP 211.A OD1 no hydrogen 2.902 N/A GLN 215.A N ASP 211.A O no hydrogen 2.720 N/A GLN 215.A NE2 TRP 171.A O no hydrogen 3.596 N/A GLN 215.A NE2 PHE 207.A O no hydrogen 3.214 N/A LEU 216.A N HIS 212.A O no hydrogen 3.003 N/A LYS 217.A N ILE 213.A O no hydrogen 3.129 N/A LEU 218.A N ASP 214.A O no hydrogen 2.968 N/A ILE 219.A N GLN 215.A O no hydrogen 2.950 N/A LEU 220.A N LEU 216.A O no hydrogen 2.935 N/A ARG 221.A N LYS 217.A O no hydrogen 3.002 N/A LEU 222.A N ILE 219.A O no hydrogen 2.999 N/A VAL 223.A N ILE 219.A O no hydrogen 3.144 N/A GLY 224.A N LEU 220.A O no hydrogen 2.875 N/A THR 225.A N MET 249.A O no hydrogen 2.946 N/A LEU 231.A N GLY 227.A O no hydrogen 2.815 N/A LYS 232.A N ALA 228.A O no hydrogen 3.228 N/A LYS 233.A N LEU 230.A O no hydrogen 2.711 N/A LYS 233.A NZ ASP 276.A OD1 no hydrogen 3.210 N/A LYS 233.A NZ ASP 276.A OD2 no hydrogen 2.542 N/A LYS 233.A NZ ASP 278.A OD2 no hydrogen 2.688 N/A ILE 234.A N LEU 231.A O no hydrogen 3.187 N/A SER 236.A N TRP 181.A O no hydrogen 3.147 N/A ARG 240.A N SER 236.A O no hydrogen 2.956 N/A ARG 240.A NH1 ILE 234.A O no hydrogen 2.695 N/A ASN 241.A N GLU 237.A O no hydrogen 2.813 N/A ASN 241.A ND2 GLN 244.A OE1 no hydrogen 3.552 N/A TYR 242.A N SER 238.A O no hydrogen 3.256 N/A ILE 243.A N ALA 239.A O no hydrogen 3.247 N/A GLN 244.A N ARG 240.A O no hydrogen 2.935 N/A SER 245.A N TYR 242.A O no hydrogen 3.020 N/A SER 245.A OG TYR 242.A O no hydrogen 2.294 N/A LEU 246.A N ILE 243.A O no hydrogen 2.863 N/A MET 249.A N THR 225.A OG1 no hydrogen 3.130 N/A LYS 251.A NZ MET 252.A O no hydrogen 2.745 N/A LYS 251.A NZ GLU 270.A OE1 no hydrogen 2.688 N/A LYS 251.A NZ GLU 270.A OE2 no hydrogen 3.534 N/A MET 252.A N LEU 222.A O no hydrogen 2.795 N/A PHE 254.A N GLU 270.A OE2 no hydrogen 3.235 N/A ALA 255.A N ASN 253.A OD1 no hydrogen 3.081 N/A ASN 256.A N ASN 253.A O no hydrogen 3.213 N/A VAL 257.A N PHE 254.A O no hydrogen 3.047 N/A PHE 258.A N PHE 254.A O no hydrogen 2.809 N/A ALA 261.A N PHE 258.A O no hydrogen 3.351 N/A ASN 262.A ND2 ASP 116.A OD2 no hydrogen 2.986 N/A LEU 264.A N ASN 262.A OD1 no hydrogen 3.042 N/A ALA 265.A N ASN 262.A O no hydrogen 2.917 N/A VAL 266.A N ASN 262.A O no hydrogen 3.055 N/A ASP 267.A N PRO 263.A O no hydrogen 3.042 N/A LEU 268.A N LEU 264.A O no hydrogen 3.128 N/A LEU 269.A N ALA 265.A O no hydrogen 2.980 N/A GLU 270.A N VAL 266.A O no hydrogen 2.915 N/A LYS 271.A N LEU 268.A O no hydrogen 2.845 N/A LYS 271.A NZ ASP 267.A OD1 no hydrogen 3.230 N/A LYS 271.A NZ ASP 267.A OD2 no hydrogen 2.848 N/A MET 272.A N LEU 269.A O no hydrogen 3.016 N/A LEU 273.A N LEU 269.A O no hydrogen 2.869 N/A ASP 278.A N ASP 276.A OD1 no hydrogen 2.971 N/A LYS 279.A N ASP 276.A O no hydrogen 2.875 N/A ARG 280.A NE VAL 274.A O no hydrogen 2.685 N/A ARG 280.A NH1 GLU 176.A OE2 no hydrogen 2.943 N/A ARG 280.A NH1 THR 187.A O no hydrogen 3.196 N/A ARG 280.A NH2 GLU 176.A OE1 no hydrogen 3.200 N/A ARG 280.A NH2 VAL 274.A O no hydrogen 2.700 N/A ILE 281.A N LYS 271.A O no hydrogen 2.835 N/A THR 282.A N GLN 285.A OE1 no hydrogen 3.112 N/A ALA 286.A N THR 282.A O no hydrogen 2.962 N/A LEU 287.A N ALA 283.A O no hydrogen 3.152 N/A ALA 288.A N GLN 285.A O no hydrogen 3.115 N/A HIS 289.A N ALA 286.A O no hydrogen 3.125 N/A HIS 289.A NE2 ASP 267.A OD2 no hydrogen 2.840 N/A TYR 291.A N HIS 289.A ND1 no hydrogen 3.285 N/A TYR 291.A OH ASP 116.A OD1 no hydrogen 2.729 N/A PHE 292.A N HIS 289.A O no hydrogen 3.162 N/A ALA 293.A N ALA 290.A O no hydrogen 3.151 N/A TYR 295.A N PHE 292.A O no hydrogen 3.009 N/A TYR 295.A OH ASP 117.A OD1 no hydrogen 3.349 N/A HIS 296.A N PHE 292.A O no hydrogen 2.657 N/A HIS 296.A ND1 GLU 301.A OE2 no hydrogen 2.709 N/A ASP 297.A N GLU 301.A OE2 no hydrogen 3.161 N/A ASP 299.A N ASP 297.A OD1 no hydrogen 3.304 N/A ASP 300.A N ASP 297.A O no hydrogen 2.886 N/A ALA 304.A N SER 135.A OG no hydrogen 2.590 N/A GLN 309.A NE2 ASP 137.A O no hydrogen 3.032 N/A SER 310.A N ASP 308.A OD1 no hydrogen 3.050 N/A SER 310.A OG ASP 308.A OD1 no hydrogen 2.274 N/A GLU 312.A N GLN 309.A O no hydrogen 2.989 N/A SER 313.A N SER 310.A O no hydrogen 2.999 N/A ARG 314.A N PHE 311.A O no hydrogen 3.106 N/A LEU 317.A N GLU 320.A OE1 no hydrogen 2.854 N/A GLU 320.A N LEU 317.A O no hydrogen 2.712 N/A TRP 321.A N LEU 317.A O no hydrogen 2.972 N/A LYS 322.A N ILE 318.A O no hydrogen 2.909 N/A LYS 322.A NZ ASN 96.A OD1 no hydrogen 3.501 N/A SER 323.A N ASP 319.A O no hydrogen 3.048 N/A LEU 324.A N GLU 320.A O no hydrogen 2.956 N/A THR 325.A N TRP 321.A O no hydrogen 2.961 N/A THR 325.A OG1 TRP 321.A O no hydrogen 2.659 N/A TYR 326.A N LYS 322.A O no hydrogen 2.974 N/A ASP 327.A N SER 323.A O no hydrogen 2.988 N/A GLU 328.A N LEU 324.A O no hydrogen 3.053 N/A VAL 329.A N THR 325.A O no hydrogen 3.072 N/A VAL 329.A N TYR 326.A O no hydrogen 3.020 N/A ILE 330.A N TYR 326.A O no hydrogen 3.060 N/A ILE 330.A N ASP 327.A O no hydrogen 3.274 N/A SER 331.A N ASP 327.A O no hydrogen 2.947 N/A SER 331.A OG ASP 327.A O no hydrogen 3.403 N/A PHE 332.A N VAL 329.A O no hydrogen 3.422 N/A