Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3no3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 VAL 210.A O no hydrogen 2.589 N/A LYS 6.A N ASP 211.A O no hydrogen 2.837 N/A ILE 8.A N ILE 213.A O no hydrogen 2.911 N/A ALA 9.A N GLY 37.A O no hydrogen 2.932 N/A HIS 10.A N THR 215.A O no hydrogen 2.992 N/A HIS 10.A ND1 ASP 216.A OD1 no hydrogen 2.914 N/A ARG 11.A N GLU 39.A OE1 no hydrogen 2.975 N/A ARG 11.A NH1 GLN 21.A OE1 no hydrogen 2.823 N/A GLY 12.A N ALA 9.A O no hydrogen 2.984 N/A TYR 13.A N SER 26.A O no hydrogen 2.812 N/A TYR 13.A OH GLU 219.A OE1 no hydrogen 2.541 N/A TRP 14.A NE1 ASP 216.A OD1 no hydrogen 3.055 N/A SER 19.A N THR 16.A O no hydrogen 3.102 N/A SER 19.A OG TYR 13.A O no hydrogen 2.808 N/A ASN 22.A N ARG 11.A O no hydrogen 2.946 N/A ASN 22.A ND2 ASP 41.A OD2 no hydrogen 2.886 N/A SER 23.A N SER 26.A OG no hydrogen 3.128 N/A SER 23.A OG ALA 20.A O no hydrogen 2.689 N/A ILE 24.A N GLU 80.A OE1 no hydrogen 2.935 N/A ARG 25.A N GLU 80.A OE2 no hydrogen 3.083 N/A ARG 25.A NE.B GLU 17.A O no hydrogen 3.323 N/A ARG 25.A NH1.A GLU 28.A OE1 no hydrogen 2.847 N/A ARG 25.A NH1.B GLU 17.A O no hydrogen 2.767 N/A SER 26.A N SER 23.A OG no hydrogen 2.914 N/A SER 26.A OG ARG 11.A O no hydrogen 2.733 N/A SER 26.A OG ALA 20.A O no hydrogen 3.342 N/A SER 26.A OG SER 23.A O no hydrogen 3.186 N/A LEU 27.A N SER 23.A O no hydrogen 3.155 N/A GLU 28.A N ILE 24.A O no hydrogen 2.905 N/A ARG 29.A N ARG 25.A O no hydrogen 2.849 N/A ARG 29.A NH1 GLU 32.A OE1 no hydrogen 2.857 N/A ARG 29.A NH2 THR 16.A OG1 no hydrogen 3.022 N/A ALA 30.A N SER 26.A O no hydrogen 2.942 N/A SER 31.A N LEU 27.A O no hydrogen 3.173 N/A SER 31.A OG ASN 97.A OD1 no hydrogen 2.879 N/A GLU 32.A N GLU 28.A O no hydrogen 2.823 N/A ILE 33.A N ARG 29.A O no hydrogen 2.984 N/A GLY 34.A N SER 31.A O no hydrogen 2.980 N/A ALA 35.A N ALA 30.A O no hydrogen 3.112 N/A GLY 37.A N VAL 7.A O no hydrogen 3.161 N/A SER 38.A N ARG 99.A O no hydrogen 2.977 N/A GLU 39.A N ALA 9.A O no hydrogen 3.020 N/A PHE 40.A N ILE 101.A O no hydrogen 3.044 N/A ASP 41.A N ASN 22.A OD1 no hydrogen 3.145 N/A VAL 42.A N GLU 103.A O no hydrogen 2.786 N/A HIS 43.A N VAL 51.A O no hydrogen 2.978 N/A LEU 44.A N HIS 107.A NE2 no hydrogen 3.026 N/A THR 45.A N VAL 49.A O no hydrogen 2.841 N/A THR 45.A OG1 ASP 47.A OD1 no hydrogen 2.648 N/A THR 45.A OG1 VAL 49.A O no hydrogen 3.288 N/A ALA 46.A N CYS 66.A O no hydrogen 2.964 N/A ASN 48.A N THR 45.A O no hydrogen 2.928 N/A VAL 49.A N THR 45.A OG1 no hydrogen 2.996 N/A VAL 51.A N HIS 43.A O no hydrogen 2.900 N/A VAL 52.A N PRO 83.A O no hydrogen 3.030 N/A TYR 53.A N ASP 41.A O no hydrogen 2.919 N/A ILE 58.A N LYS 61.A O no hydrogen 2.844 N/A GLN 59.A NE2 GLN 75.A O no hydrogen 2.960 N/A LYS 61.A N ILE 58.A O no hydrogen 2.905 N/A LYS 61.A NZ GLU 70.A O no hydrogen 2.762 N/A HIS 62.A ND1 SER 65.A OG no hydrogen 2.703 N/A ILE 63.A N ASN 56.A O no hydrogen 3.024 N/A GLN 64.A NE2 HIS 43.A ND1 no hydrogen 3.091 N/A GLN 64.A NE2 SER 106.A O no hydrogen 3.029 N/A SER 65.A N HIS 62.A O no hydrogen 3.214 N/A SER 65.A OG HIS 62.A ND1 no hydrogen 2.703 N/A SER 65.A OG HIS 62.A O no hydrogen 3.415 N/A CYS 66.A N ILE 63.A O no hydrogen 3.177 N/A CYS 66.A SG HIS 62.A O no hydrogen 3.235 N/A CYS 66.A SG GLU 70.A OE1 no hydrogen 3.638 N/A THR 67.A N GLU 70.A OE2 no hydrogen 2.974 N/A THR 67.A OG1 GLU 70.A OE2 no hydrogen 3.478 N/A TYR 68.A N ASP 47.A OD1 no hydrogen 2.841 N/A GLU 70.A N THR 67.A OG1 no hydrogen 3.359 N/A LEU 71.A N TYR 68.A O no hydrogen 2.927 N/A LYS 72.A NZ ASP 69.A OD1.A no hydrogen 3.478 N/A LYS 72.A NZ ASP 73.A OD2 no hydrogen 3.254 N/A LEU 74.A N LEU 71.A O no hydrogen 3.116 N/A LEU 76.A N GLU 80.A O no hydrogen 2.702 N/A ASN 78.A ND2 GLY 18.A O no hydrogen 2.941 N/A ASN 78.A ND2 GLU 80.A OE2 no hydrogen 3.065 N/A GLY 79.A N LEU 76.A O no hydrogen 2.920 N/A GLU 80.A N ASN 78.A OD1 no hydrogen 3.229 N/A LEU 82.A N LEU 74.A O no hydrogen 2.967 N/A THR 84.A N GLN 87.A OE1 no hydrogen 3.131 N/A LEU 85.A N LEU 50.A O no hydrogen 2.900 N/A GLN 87.A N THR 84.A OG1 no hydrogen 2.973 N/A TYR 88.A N THR 84.A O no hydrogen 3.045 N/A TYR 88.A OH SER 23.A O no hydrogen 2.743 N/A LEU 89.A N LEU 85.A O no hydrogen 2.804 N/A LYS 90.A N GLU 86.A O no hydrogen 2.854 N/A ARG 91.A N GLN 87.A O no hydrogen 3.098 N/A ARG 91.A NE GLU 28.A OE2 no hydrogen 2.719 N/A ARG 91.A NH1 ARG 91.A O no hydrogen 3.344 N/A ARG 91.A NH2 GLU 28.A OE2 no hydrogen 3.393 N/A ALA 92.A N TYR 88.A O no hydrogen 2.968 N/A LYS 93.A N LEU 89.A O no hydrogen 2.897 N/A LYS 93.A NZ LYS 126.A O no hydrogen 2.637 N/A LYS 94.A N ARG 91.A O no hydrogen 3.153 N/A LEU 95.A N ALA 92.A O no hydrogen 2.984 N/A LYS 96.A NZ LYS 93.A O no hydrogen 2.994 N/A ASN 97.A ND2 SER 31.A O no hydrogen 2.925 N/A ARG 99.A N TYR 36.A O no hydrogen 2.934 N/A ARG 99.A NE ASP 132.A OD1 no hydrogen 2.985 N/A ARG 99.A NE ASP 132.A OD2 no hydrogen 3.333 N/A ARG 99.A NH2 ASP 132.A OD1 no hydrogen 2.627 N/A LEU 100.A N ARG 130.A O no hydrogen 2.823 N/A ILE 101.A N SER 38.A O no hydrogen 2.978 N/A PHE 102.A N ASP 132.A O no hydrogen 2.874 N/A GLU 103.A N PHE 40.A O no hydrogen 2.816 N/A LEU 104.A N ILE 134.A O no hydrogen 3.095 N/A LYS 105.A N VAL 42.A O no hydrogen 2.904 N/A LYS 105.A NZ HIS 54.A O no hydrogen 2.859 N/A HIS 107.A N ASN 113.A OD1 no hydrogen 2.828 N/A HIS 107.A ND1 LYS 105.A O no hydrogen 2.779 N/A ARG 112.A N THR 109.A OG1 no hydrogen 2.818 N/A ARG 112.A NH1 ASN 48.A OD1 no hydrogen 2.903 N/A ARG 112.A NH2 ASN 48.A OD1 no hydrogen 2.890 N/A ASN 113.A N THR 109.A O no hydrogen 3.006 N/A ASN 113.A ND2 HIS 107.A O no hydrogen 3.018 N/A ASN 113.A ND2 THR 109.A O no hydrogen 2.844 N/A ARG 114.A N PRO 110.A O no hydrogen 2.965 N/A ASP 115.A N GLU 111.A O no hydrogen 2.957 N/A ALA 116.A N ARG 112.A O no hydrogen 2.874 N/A ALA 117.A N ASN 113.A O no hydrogen 2.961 N/A ARG 118.A N ARG 114.A O no hydrogen 2.855 N/A ARG 118.A NH1 ASP 115.A OD1 no hydrogen 2.783 N/A ARG 118.A NH2 ASP 115.A OD1 no hydrogen 3.339 N/A LEU 119.A N ASP 115.A O no hydrogen 2.978 N/A SER 120.A N ALA 116.A O no hydrogen 2.918 N/A SER 120.A OG ALA 116.A O no hydrogen 2.823 N/A VAL 121.A N ALA 117.A O no hydrogen 2.976 N/A GLN 122.A N ARG 118.A O no hydrogen 3.003 N/A LYS 124.A N VAL 121.A O no hydrogen 2.889 N/A ARG 125.A N GLN 122.A O no hydrogen 2.941 N/A ARG 125.A NH2 GLU 86.A OE2 no hydrogen 2.866 N/A LEU 127.A N VAL 123.A O no hydrogen 3.103 N/A ARG 130.A N LEU 127.A O no hydrogen 3.082 N/A ARG 130.A NE ILE 98.A O no hydrogen 3.285 N/A ARG 130.A NH1 ALA 92.A O no hydrogen 3.206 N/A ARG 130.A NH1 LYS 93.A O no hydrogen 3.556 N/A ARG 130.A NH2 ALA 92.A O no hydrogen 3.118 N/A ARG 130.A NH2 ILE 98.A O no hydrogen 2.854 N/A THR 131.A OG1 LEU 127.A O no hydrogen 2.725 N/A ASP 132.A N LEU 100.A O no hydrogen 2.902 N/A TYR 133.A N GLU 151.A O no hydrogen 2.917 N/A ILE 134.A N PHE 102.A O no hydrogen 2.946 N/A SER 135.A N SER 153.A O no hydrogen 3.408 N/A SER 135.A OG LEU 104.A O no hydrogen 2.835 N/A ASN 137.A N SER 135.A OG no hydrogen 3.022 N/A ASN 137.A ND2 SER 106.A OG.A no hydrogen 3.176 N/A ALA 139.A N ASN 137.A OD1 no hydrogen 2.894 N/A CYS 140.A N ASN 137.A O no hydrogen 3.099 N/A CYS 140.A SG SER 135.A O no hydrogen 3.549 N/A CYS 140.A SG ASN 137.A O no hydrogen 3.347 N/A GLU 142.A N ASP 138.A O no hydrogen 3.173 N/A PHE 143.A N ALA 139.A O no hydrogen 2.996 N/A ILE 144.A N CYS 140.A O no hydrogen 2.959 N/A ARG 145.A N LYS 141.A O no hydrogen 2.898 N/A ARG 145.A NE GLU 142.A OE1 no hydrogen 2.925 N/A ARG 145.A NH2 GLU 142.A OE2 no hydrogen 2.649 N/A LEU 146.A N GLU 142.A O no hydrogen 2.910 N/A CYS 147.A N PHE 143.A O no hydrogen 2.787 N/A SER 150.A N CYS 147.A O no hydrogen 3.019 N/A VAL 152.A N THR 169.A OG1 no hydrogen 2.997 N/A SER 153.A N TYR 133.A O no hydrogen 2.898 N/A TYR 154.A OH GLU 158.A OE1 no hydrogen 3.355 N/A TYR 154.A OH GLU 158.A OE2 no hydrogen 2.547 N/A LEU 155.A N SER 135.A O no hydrogen 3.021 N/A ASN 156.A ND2 GLU 158.A OE1 no hydrogen 2.737 N/A GLU 158.A N GLU 158.A OE1 no hydrogen 2.846 N/A SER 160.A N GLU 162.A OE1 no hydrogen 2.858 N/A SER 160.A OG GLU 162.A OE1 no hydrogen 3.313 N/A LEU 163.A N SER 160.A O no hydrogen 2.898 N/A LYS 164.A N PRO 161.A O no hydrogen 2.756 N/A LYS 164.A NZ.A LEU 191.A O no hydrogen 2.663 N/A LEU 166.A N GLU 162.A O no hydrogen 3.393 N/A GLY 167.A N LYS 164.A O no hydrogen 3.004 N/A PHE 168.A N LEU 163.A O no hydrogen 3.111 N/A THR 169.A N VAL 152.A O no hydrogen 2.983 N/A THR 169.A OG1 GLU 151.A OE1 no hydrogen 2.861 N/A THR 169.A OG1 VAL 152.A O no hydrogen 3.386 N/A LEU 171.A N THR 193.A O no hydrogen 3.016 N/A ASP 172.A N TYR 154.A O no hydrogen 3.002 N/A TYR 173.A N ASN 195.A O no hydrogen 3.029 N/A TYR 173.A OH LEU 159.A O no hydrogen 2.584 N/A TYR 175.A N TRP 197.A O no hydrogen 3.143 N/A LYS 176.A N HIS 174.A ND1 no hydrogen 3.442 N/A VAL 177.A N HIS 174.A O no hydrogen 2.997 N/A GLN 179.A N TYR 175.A O no hydrogen 2.914 N/A GLN 179.A NE2 GLU 206.A OE2.A no hydrogen 2.833 N/A SER 180.A N LYS 176.A O no hydrogen 2.797 N/A SER 180.A OG LYS 176.A O no hydrogen 2.934 N/A HIS 181.A N VAL 177.A O no hydrogen 2.815 N/A TRP 184.A N HIS 181.A O no hydrogen 3.140 N/A ASP 187.A N ASP 183.A O no hydrogen 3.046 N/A CYS 188.A N TRP 184.A O no hydrogen 2.997 N/A CYS 188.A SG TRP 184.A O no hydrogen 3.505 N/A CYS 188.A SG THR 193.A O no hydrogen 3.831 N/A LYS 189.A N VAL 185.A O no hydrogen 3.209 N/A VAL 190.A N LYS 186.A O no hydrogen 2.975 N/A LEU 191.A N ASP 187.A O no hydrogen 2.860 N/A GLY 192.A N LYS 189.A O no hydrogen 3.091 N/A THR 193.A N THR 169.A O no hydrogen 3.013 N/A SER 194.A N ASP 211.A OD2 no hydrogen 2.837 N/A SER 194.A OG ASP 211.A OD2 no hydrogen 3.296 N/A ASN 195.A N LEU 171.A O no hydrogen 2.895 N/A VAL 196.A N PHE 212.A O no hydrogen 3.261 N/A TRP 197.A N TYR 173.A O no hydrogen 3.217 N/A TRP 197.A NE1 ASP 172.A O no hydrogen 2.940 N/A VAL 199.A N THR 214.A O no hydrogen 2.899 N/A LEU 204.A N ASP 201.A OD2.B no hydrogen 3.015 N/A GLU 206.A N LYS 203.A O no hydrogen 2.929 N/A ASP 208.A N GLU 205.A O no hydrogen 2.875 N/A ASP 211.A N SER 194.A OG no hydrogen 3.175 N/A PHE 212.A N SER 194.A O no hydrogen 3.011 N/A ILE 213.A N LYS 6.A O no hydrogen 3.015 N/A THR 214.A N VAL 196.A O no hydrogen 2.820 N/A THR 214.A OG1 ASN 195.A OD1 no hydrogen 2.825 N/A THR 215.A N ILE 8.A O no hydrogen 3.001 N/A THR 215.A OG1 VAL 199.A O no hydrogen 2.761 N/A THR 215.A OG1 ASP 200.A OD1 no hydrogen 3.059 N/A ASP 216.A N ASP 200.A OD1 no hydrogen 2.830 N/A LEU 217.A N THR 215.A OG1 no hydrogen 2.888 N/A THR 221.A N LEU 217.A O no hydrogen 3.409 N/A THR 221.A OG1 LEU 217.A O no hydrogen 3.506 N/A GLN 222.A N PRO 218.A O no hydrogen 3.021 N/A GLN 222.A NE2 ILE 33.A O no hydrogen 2.884 N/A LYS 223.A N GLU 219.A O no hydrogen 2.948 N/A LYS 223.A NZ GLU 220.A OE1.A no hydrogen 2.737 N/A ILE 224.A N GLU 220.A O no hydrogen 3.031 N/A LEU 225.A N THR 221.A O no hydrogen 2.980 N/A HIS 226.A N GLN 222.A O no hydrogen 2.887 N/A SER 227.A N LYS 223.A O no hydrogen 2.914 N/A SER 227.A OG.A LYS 223.A O no hydrogen 3.011 N/A SER 227.A OG.B LYS 223.A O no hydrogen 3.507 N/A SER 227.A OG.B ILE 224.A O no hydrogen 2.960 N/A ARG 228.A N ILE 224.A O no hydrogen 3.107 N/A ARG 228.A NE ASP 3.A OD2 no hydrogen 2.926 N/A ARG 228.A NH1 GLU 205.A OE1 no hydrogen 3.120 N/A ARG 228.A NH1 ASP 208.A OD1 no hydrogen 3.037 N/A ARG 228.A NH2 ASP 3.A OD1 no hydrogen 2.953 N/A ARG 228.A NH2 ASP 208.A OD1 no hydrogen 3.010 N/A ALA 229.A N LEU 225.A O no hydrogen 3.059 N/A ALA 229.A N HIS 226.A O no hydrogen 3.134 N/A GLN 230.A N SER 227.A O no hydrogen 3.252 N/A GLN 230.A NE2 HIS 226.A O no hydrogen 2.660 N/A