Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3o0d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 2.A OH GLU 209.A OE1 no hydrogen 2.659 N/A SER 4.A N SER 269.A O no hydrogen 3.192 N/A GLU 6.A N SER 4.A OG no hydrogen 3.063 N/A SER 8.A N MET 264.A O no hydrogen 2.937 N/A GLN 12.A NE2 ASN 16.A OD1 no hydrogen 2.972 N/A SER 14.A N ASP 11.A OD1 no hydrogen 2.943 N/A SER 14.A OG ASP 11.A OD1 no hydrogen 2.812 N/A TYR 15.A N ASP 11.A O no hydrogen 2.996 N/A TYR 15.A OH PRO 257.A O no hydrogen 2.574 N/A ASN 16.A N GLN 12.A O no hydrogen 2.813 N/A PHE 17.A N GLU 13.A O no hydrogen 3.087 N/A PHE 18.A N SER 14.A O no hydrogen 3.003 N/A GLU 19.A N TYR 15.A O no hydrogen 2.948 N/A LYS 20.A N ASN 16.A O no hydrogen 2.864 N/A LYS 20.A NZ GLN 80.A OE1 no hydrogen 2.789 N/A LYS 20.A NZ TYR 82.A OH no hydrogen 3.129 N/A TYR 21.A N PHE 17.A O no hydrogen 3.318 N/A ALA 22.A N PHE 18.A O no hydrogen 2.971 N/A ARG 23.A N GLU 19.A O no hydrogen 2.930 N/A ARG 23.A NH1 GLN 46.A OE1 no hydrogen 2.844 N/A LEU 24.A N LYS 20.A O no hydrogen 3.003 N/A ALA 25.A N TYR 21.A O no hydrogen 2.827 N/A ASN 26.A N ALA 22.A O no hydrogen 3.039 N/A ASN 26.A ND2 THR 295.A O no hydrogen 2.844 N/A ASN 26.A ND2 ILE 301.A O no hydrogen 3.005 N/A ILE 27.A N ARG 23.A O no hydrogen 3.125 N/A GLY 28.A N ALA 25.A O no hydrogen 3.008 N/A TYR 29.A N ASN 26.A O no hydrogen 2.919 N/A CYS 30.A N ILE 27.A O no hydrogen 2.852 N/A VAL 31.A N GLY 28.A O no hydrogen 3.290 N/A THR 35.A N.A GLY 32.A O no hydrogen 3.313 N/A THR 35.A N.B GLY 32.A O no hydrogen 3.324 N/A THR 35.A OG1.B GLY 32.A O no hydrogen 3.486 N/A ILE 37.A N GLU 58.A OE1 no hydrogen 3.231 N/A PHE 38.A N ASN 42.A O no hydrogen 2.825 N/A ASN 42.A N PHE 38.A O no hydrogen 2.778 N/A GLN 46.A NE2 ILE 301.A O no hydrogen 3.549 N/A GLN 46.A NE2 ILE 301.A OXT no hydrogen 2.982 N/A ALA 48.A N GLY 44.A O no hydrogen 3.118 N/A HIS 49.A N GLN 46.A O no hydrogen 3.194 N/A HIS 49.A ND1 LEU 45.A O no hydrogen 3.132 N/A PHE 50.A N CYS 47.A O no hydrogen 3.000 N/A GLU 54.A N VAL 74.A O no hydrogen 2.867 N/A LEU 55.A N PRO 40.A O no hydrogen 2.806 N/A ILE 56.A N LEU 72.A O no hydrogen 2.779 N/A GLU 57.A N LEU 72.A O no hydrogen 3.295 N/A PHE 59.A N GLY 70.A O no hydrogen 2.963 N/A ASP 61.A N VAL 68.A O no hydrogen 3.076 N/A ARG 63.A N ASP 61.A OD1 no hydrogen 3.053 N/A ARG 63.A NE ASP 61.A OD1 no hydrogen 2.951 N/A ARG 63.A NE ASP 61.A OD2 no hydrogen 3.480 N/A ARG 63.A NH2 ASP 61.A OD2 no hydrogen 3.011 N/A LEU 64.A N ASP 67.A OD2 no hydrogen 3.073 N/A ASP 67.A N LEU 64.A O no hydrogen 3.076 N/A SER 69.A N ARG 86.A O.A no hydrogen 3.136 N/A SER 69.A N ARG 86.A O.B no hydrogen 2.889 N/A SER 69.A OG HIS 60.A ND1 no hydrogen 3.109 N/A SER 69.A OG THR 88.A OG1 no hydrogen 2.847 N/A GLY 70.A N PHE 59.A O no hydrogen 2.897 N/A TYR 71.A N VAL 84.A O no hydrogen 2.916 N/A TYR 71.A OH LEU 24.A O no hydrogen 2.774 N/A LEU 72.A N GLU 57.A O no hydrogen 2.883 N/A ALA 73.A N TYR 82.A O no hydrogen 2.899 N/A VAL 74.A N GLU 54.A O no hydrogen 2.901 N/A ASP 75.A N GLN 80.A O no hydrogen 2.774 N/A HIS 76.A N ASN 52.A O no hydrogen 2.917 N/A HIS 76.A ND1 TYR 154.A OH no hydrogen 2.858 N/A HIS 76.A NE2 GLU 54.A OE2 no hydrogen 2.751 N/A ALA 77.A N ASP 75.A OD1 no hydrogen 2.787 N/A SER 78.A N ASP 75.A OD1 no hydrogen 2.868 N/A SER 78.A OG GLN 80.A OE1 no hydrogen 2.756 N/A SER 78.A OG TYR 82.A OH no hydrogen 3.305 N/A LYS 79.A NZ HIS 76.A O no hydrogen 3.422 N/A LYS 79.A NZ ALA 77.A O no hydrogen 3.001 N/A GLN 80.A N ASP 75.A O no hydrogen 2.963 N/A GLN 80.A NE2 TYR 21.A OH no hydrogen 2.959 N/A GLN 80.A NE2 GLN 155.A OE1 no hydrogen 2.784 N/A ILE 81.A N GLN 155.A O no hydrogen 2.843 N/A TYR 82.A N ALA 73.A O no hydrogen 2.741 N/A TYR 82.A OH ASP 75.A OD2 no hydrogen 2.722 N/A TYR 82.A OH GLN 80.A OE1 no hydrogen 3.213 N/A LEU 83.A N ALA 157.A O no hydrogen 2.924 N/A VAL 84.A N TYR 71.A O no hydrogen 2.952 N/A ILE 85.A N THR 159.A O no hydrogen 3.044 N/A ARG 86.A N.A SER 69.A O no hydrogen 2.885 N/A ARG 86.A N.B SER 69.A O no hydrogen 2.905 N/A ARG 86.A NE.A GLY 87.A O no hydrogen 2.865 N/A ARG 86.A NE.B GLY 28.A O no hydrogen 3.123 N/A ARG 86.A NE.B VAL 31.A O no hydrogen 3.347 N/A ARG 86.A NH1.A VAL 31.A O no hydrogen 2.864 N/A ARG 86.A NH1.B THR 88.A O no hydrogen 3.221 N/A ARG 86.A NH2.A GLY 87.A O no hydrogen 3.283 N/A ARG 86.A NH2.B VAL 31.A O no hydrogen 2.679 N/A THR 88.A N ASP 67.A O no hydrogen 2.910 N/A THR 88.A OG1 ASP 61.A O no hydrogen 2.695 N/A THR 88.A OG1 SER 69.A OG no hydrogen 2.847 N/A HIS 89.A NE2 PRO 62.A O no hydrogen 2.659 N/A ASP 93.A N SER 90.A OG no hydrogen 3.072 N/A VAL 94.A N SER 90.A O no hydrogen 2.918 N/A ILE 95.A N LEU 91.A O no hydrogen 2.851 N/A THR 96.A N GLU 92.A O no hydrogen 3.017 N/A THR 96.A OG1 GLU 92.A O no hydrogen 2.808 N/A ASP 97.A N ASP 93.A O no hydrogen 3.127 N/A ILE 98.A N VAL 94.A O no hydrogen 3.012 N/A ARG 99.A N.A ILE 95.A O no hydrogen 2.937 N/A ARG 99.A N.B ILE 95.A O no hydrogen 2.941 N/A ARG 99.A NH1.B ARG 99.A O.B no hydrogen 3.007 N/A ILE 100.A N THR 96.A O no hydrogen 3.129 N/A MET 101.A N ASP 97.A O no hydrogen 3.008 N/A THR 106.A N VAL 125.A O.A no hydrogen 2.965 N/A THR 106.A N VAL 125.A O.B no hydrogen 2.722 N/A THR 106.A OG1 PRO 104.A O no hydrogen 3.484 N/A ASN 107.A ND2 ASP 121.A O no hydrogen 2.963 N/A PHE 108.A N CYS 123.A O no hydrogen 2.943 N/A ASP 109.A N ASN 107.A OD1 no hydrogen 3.021 N/A LEU 110.A N ASN 107.A O no hydrogen 2.960 N/A ALA 111.A N PHE 108.A O no hydrogen 2.920 N/A ALA 112.A N ASN 134.A OD1 no hydrogen 2.788 N/A ILE 114.A N ALA 111.A O no hydrogen 3.267 N/A ALA 118.A N SER 115.A O no hydrogen 3.079 N/A THR 119.A OG1 ASN 107.A OD1 no hydrogen 3.394 N/A CYS 120.A SG GLY 196.A O no hydrogen 3.812 N/A CYS 123.A N CYS 120.A O no hydrogen 3.193 N/A CYS 123.A SG.B GLY 196.A O no hydrogen 3.985 N/A LEU 124.A N ASN 194.A OD1 no hydrogen 3.324 N/A VAL 125.A N.A THR 106.A O no hydrogen 2.755 N/A VAL 125.A N.B THR 106.A O no hydrogen 2.760 N/A HIS 126.A N VAL 192.A O no hydrogen 2.965 N/A PHE 129.A N HIS 126.A ND1 no hydrogen 3.261 N/A ILE 130.A N HIS 126.A O no hydrogen 2.990 N/A GLN 131.A N ASN 127.A O no hydrogen 3.148 N/A GLN 131.A NE2 ASP 67.A OD1 no hydrogen 3.056 N/A SER 132.A N GLY 128.A O no hydrogen 3.073 N/A SER 132.A OG.A PHE 66.A O no hydrogen 2.856 N/A SER 132.A OG.A GLY 128.A O no hydrogen 3.101 N/A SER 132.A OG.B PHE 129.A O no hydrogen 2.852 N/A TYR 133.A N PHE 129.A O no hydrogen 2.951 N/A TYR 133.A OH ALA 112.A O no hydrogen 2.618 N/A ASN 134.A N ILE 130.A O no hydrogen 2.757 N/A ASN 135.A N GLN 131.A O no hydrogen 2.790 N/A THR 136.A N SER 132.A O no hydrogen 2.985 N/A THR 136.A OG1 SER 132.A O no hydrogen 2.811 N/A TYR 137.A N TYR 133.A O no hydrogen 2.999 N/A ASN 138.A N ASN 134.A O no hydrogen 2.856 N/A GLN 139.A N ASN 135.A O no hydrogen 3.337 N/A GLN 139.A N THR 136.A O no hydrogen 3.078 N/A GLN 139.A NE2 VAL 68.A O no hydrogen 3.218 N/A GLN 139.A NE2 ASN 135.A O no hydrogen 3.220 N/A ILE 140.A N THR 136.A O no hydrogen 2.975 N/A GLY 141.A N TYR 137.A O no hydrogen 2.810 N/A LEU 144.A N ILE 140.A O no hydrogen 2.810 N/A ASP 145.A N GLY 141.A O no hydrogen 2.910 N/A SER 146.A N PRO 142.A O no hydrogen 3.025 N/A SER 146.A OG LYS 143.A O no hydrogen 2.871 N/A VAL 147.A N LYS 143.A O no hydrogen 2.938 N/A ILE 148.A N LEU 144.A O no hydrogen 2.779 N/A GLU 149.A N ASP 145.A O no hydrogen 3.070 N/A GLN 150.A N SER 146.A O no hydrogen 3.050 N/A TYR 151.A N VAL 147.A O no hydrogen 2.976 N/A TYR 154.A N TYR 151.A O no hydrogen 3.106 N/A TYR 154.A OH HIS 76.A ND1 no hydrogen 2.858 N/A GLN 155.A N LYS 79.A O no hydrogen 3.010 N/A ALA 157.A N ILE 81.A O no hydrogen 2.827 N/A VAL 158.A N LEU 183.A O no hydrogen 2.784 N/A THR 159.A N LEU 83.A O no hydrogen 2.961 N/A THR 159.A OG1 VAL 185.A O no hydrogen 2.743 N/A SER 162.A N LEU 187.A O no hydrogen 2.881 N/A SER 162.A OG HIS 289.A NE2 no hydrogen 2.666 N/A GLY 165.A N SER 162.A O no hydrogen 2.851 N/A ALA 166.A N SER 162.A O no hydrogen 3.329 N/A ALA 167.A N LEU 163.A O no hydrogen 2.920 N/A ALA 168.A N GLY 164.A O no hydrogen 2.844 N/A LEU 169.A N GLY 165.A O no hydrogen 3.059 N/A LEU 170.A N ALA 166.A O no hydrogen 3.166 N/A PHE 171.A N ALA 167.A O no hydrogen 2.736 N/A GLY 172.A N ALA 168.A O no hydrogen 2.741 N/A ILE 173.A N LEU 169.A O no hydrogen 2.939 N/A ASN 174.A N LEU 170.A O no hydrogen 2.891 N/A LEU 175.A N PHE 171.A O no hydrogen 2.934 N/A LYS 176.A N GLY 172.A O no hydrogen 2.867 N/A VAL 177.A N ILE 173.A O no hydrogen 2.877 N/A ASN 178.A N ASN 174.A O no hydrogen 3.022 N/A GLY 179.A N LYS 176.A O no hydrogen 3.324 N/A HIS 180.A N LEU 175.A O no hydrogen 2.837 N/A LEU 183.A N ILE 156.A O no hydrogen 2.825 N/A VAL 184.A N LYS 221.A O no hydrogen 2.877 N/A VAL 185.A N VAL 158.A O no hydrogen 3.004 N/A THR 186.A N TYR 223.A O no hydrogen 2.917 N/A THR 186.A OG1 GLN 189.A OE1 no hydrogen 2.721 N/A LEU 187.A N GLY 160.A O no hydrogen 2.986 N/A GLY 188.A N ILE 225.A O no hydrogen 2.954 N/A GLN 189.A NE2 PRO 190.A O no hydrogen 2.932 N/A ILE 191.A N VAL 235.A O no hydrogen 2.757 N/A ASN 194.A N LEU 124.A O no hydrogen 3.066 N/A ASN 194.A ND2 ASP 122.A O no hydrogen 3.335 N/A ASN 194.A ND2 ASP 122.A OD1 no hydrogen 3.427 N/A PHE 197.A N ASN 194.A OD1 no hydrogen 2.966 N/A ALA 198.A N ASN 194.A O no hydrogen 2.807 N/A ASN 199.A N ALA 195.A O no hydrogen 2.925 N/A TRP 200.A N GLY 196.A O no hydrogen 3.060 N/A VAL 201.A N PHE 197.A O no hydrogen 2.825 N/A ASP 202.A N ALA 198.A O no hydrogen 3.033 N/A LYS 203.A N ASN 199.A O no hydrogen 2.929 N/A LYS 203.A NZ GLU 209.A OE2 no hydrogen 3.054 N/A LEU 204.A N TRP 200.A O no hydrogen 2.827 N/A PHE 205.A N VAL 201.A O no hydrogen 2.836 N/A PHE 206.A N ASP 202.A O no hydrogen 2.757 N/A VAL 213.A N GLN 266.A OE1 no hydrogen 2.972 N/A SER 214.A N ASP 212.A OD1 no hydrogen 3.124 N/A SER 214.A OG ASP 212.A OD1 no hydrogen 2.738 N/A ARG 220.A N SER 217.A O no hydrogen 3.146 N/A ARG 220.A NE LEU 222.A O no hydrogen 2.968 N/A ARG 220.A NH1 VAL 213.A O no hydrogen 2.907 N/A ARG 220.A NH1 LYS 215.A O no hydrogen 2.980 N/A ARG 220.A NH2 LEU 222.A O no hydrogen 3.175 N/A LYS 221.A NZ ASP 181.A OD1 no hydrogen 3.539 N/A LYS 221.A NZ ASP 181.A OD2 no hydrogen 3.322 N/A TYR 223.A N VAL 184.A O no hydrogen 2.988 N/A ARG 224.A N GLY 246.A O no hydrogen 2.922 N/A ARG 224.A NE CYS 244.A O no hydrogen 3.165 N/A ARG 224.A NH2 CYS 244.A O no hydrogen 2.786 N/A ILE 225.A N THR 186.A O no hydrogen 2.792 N/A THR 226.A N VAL 248.A O no hydrogen 2.738 N/A THR 226.A OG1 GLU 247.A OE2 no hydrogen 2.678 N/A THR 226.A OG1 VAL 248.A O no hydrogen 3.464 N/A THR 226.A OG1 SER 274.A OG.A no hydrogen 3.331 N/A HIS 227.A NE2 GLN 291.A OE1 no hydrogen 3.233 N/A ARG 228.A N ILE 250.A O no hydrogen 2.958 N/A ARG 228.A NE ASP 251.A OD1 no hydrogen 2.734 N/A ARG 228.A NH1 GLN 281.A OE1 no hydrogen 2.871 N/A ARG 228.A NH2 ASP 251.A OD1 no hydrogen 3.334 N/A ARG 228.A NH2 ASP 251.A OD2 no hydrogen 3.195 N/A GLY 229.A N ASN 277.A OD1 no hydrogen 2.822 N/A ASP 230.A N HIS 227.A O no hydrogen 2.984 N/A VAL 232.A N ASP 230.A OD1 no hydrogen 2.979 N/A GLN 234.A N ILE 231.A O no hydrogen 2.805 N/A VAL 235.A N VAL 232.A O no hydrogen 3.184 N/A TYR 241.A N TRP 238.A O no hydrogen 2.872 N/A GLN 242.A N GLY 193.A O no hydrogen 3.000 N/A HIS 243.A NE2 PRO 233.A O no hydrogen 2.657 N/A CYS 244.A SG SER 245.A O no hydrogen 3.496 N/A SER 245.A N ASP 202.A OD1 no hydrogen 2.675 N/A SER 245.A N ASP 202.A OD2 no hydrogen 3.382 N/A SER 245.A OG ASP 202.A OD2 no hydrogen 2.726 N/A VAL 248.A N ARG 224.A O no hydrogen 2.780 N/A PHE 249.A N VAL 263.A O no hydrogen 2.852 N/A ILE 250.A N THR 226.A O no hydrogen 2.806 N/A ASP 251.A N ASN 261.A O no hydrogen 2.720 N/A HIS 256.A N PHE 293.A O no hydrogen 2.823 N/A ASN 261.A N PRO 258.A O no hydrogen 2.996 N/A VAL 262.A N LEU 259.A O no hydrogen 3.496 N/A VAL 263.A N PHE 249.A O no hydrogen 2.908 N/A MET 264.A N SER 8.A O no hydrogen 2.771 N/A CYS 265.A N GLU 247.A O no hydrogen 2.923 N/A CYS 265.A SG VAL 263.A O no hydrogen 3.993 N/A GLN 266.A N GLU 6.A O no hydrogen 2.971 N/A GLN 266.A NE2 ASP 212.A OD1 no hydrogen 2.998 N/A GLN 268.A N TYR 2.A O no hydrogen 2.688 N/A SER 269.A N TYR 2.A O no hydrogen 3.281 N/A ASN 270.A ND2 GLU 6.A O no hydrogen 2.941 N/A ASN 270.A ND2 GLN 266.A O no hydrogen 2.892 N/A GLN 272.A N ASN 270.A OD1 no hydrogen 2.807 N/A CYS 273.A N ASN 270.A O no hydrogen 2.835 N/A SER 274.A N GLU 247.A OE2 no hydrogen 2.944 N/A SER 274.A OG.A GLU 247.A OE2 no hydrogen 2.969 N/A SER 274.A OG.B GLU 247.A OE2 no hydrogen 2.709 N/A GLY 276.A N CYS 273.A O no hydrogen 3.010 N/A ASN 277.A N SER 274.A O no hydrogen 2.958 N/A ASN 277.A ND2 GLN 234.A OE1 no hydrogen 2.988 N/A THR 278.A N GLN 281.A OE1 no hydrogen 2.916 N/A GLN 281.A N THR 278.A OG1 no hydrogen 3.104 N/A GLN 282.A N THR 278.A O no hydrogen 3.108 N/A GLN 282.A N LEU 279.A O no hydrogen 3.195 N/A GLN 282.A NE2 GLN 234.A OE1 no hydrogen 2.940 N/A VAL 283.A N LEU 280.A O no hydrogen 3.412 N/A ASN 288.A N ASN 284.A O no hydrogen 2.929 N/A ASN 288.A ND2 GLY 229.A O no hydrogen 3.263 N/A HIS 289.A N VAL 285.A O no hydrogen 3.128 N/A HIS 289.A ND1 ASP 230.A OD2 no hydrogen 2.840 N/A HIS 289.A NE2 SER 162.A OG no hydrogen 2.666 N/A LEU 290.A N GLY 287.A O no hydrogen 3.100 N/A TYR 292.A N LEU 290.A O no hydrogen 3.206 N/A TYR 292.A N VAL 294.A O no hydrogen 3.246 N/A TYR 292.A OH ASP 230.A OD2 no hydrogen 2.581 N/A VAL 294.A N TYR 292.A O no hydrogen 2.759 N/A GLU 296.A N LEU 290.A O no hydrogen 2.725 N/A