Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3q4k_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A N GLU 57.A O no hydrogen 3.147 N/A PHE 3.A N VAL 83.A O no hydrogen 3.176 N/A VAL 5.A N ILE 81.A O no hydrogen 3.136 N/A ARG 7.A N ALA 79.A O no hydrogen 2.798 N/A ARG 7.A NE CYS 72.A O no hydrogen 2.865 N/A ARG 7.A NH1 GLU 8.A OE2 no hydrogen 2.883 N/A ARG 7.A NH2 ARG 73.A O no hydrogen 2.756 N/A HIS 9.A N GLU 6.A O no hydrogen 2.864 N/A LEU 10.A N ARG 7.A O no hydrogen 3.063 N/A LEU 11.A N ARG 7.A O no hydrogen 3.057 N/A LEU 14.A N LEU 10.A O no hydrogen 2.923 N/A GLN 15.A N LEU 11.A O no hydrogen 3.095 N/A GLN 16.A N LYS 12.A O no hydrogen 2.897 N/A GLN 16.A NE2 ARG 198.A O no hydrogen 2.988 N/A VAL 17.A N PRO 13.A O no hydrogen 2.999 N/A SER 18.A N LEU 14.A O no hydrogen 3.308 N/A SER 18.A N GLN 15.A O no hydrogen 3.195 N/A SER 18.A OG LEU 14.A O no hydrogen 2.776 N/A LEU 23.A N LEU 20.A O no hydrogen 3.344 N/A GLY 24.A N PRO 21.A O no hydrogen 3.232 N/A ASN 25.A N ILE 22.A O no hydrogen 2.991 N/A ASN 25.A ND2 THR 62.A OG1 no hydrogen 3.299 N/A LEU 26.A N VAL 63.A O no hydrogen 2.904 N/A LEU 27.A N THR 38.A O no hydrogen 2.888 N/A LEU 28.A N THR 61.A O no hydrogen 2.751 N/A GLN 29.A N SER 36.A O no hydrogen 3.077 N/A VAL 30.A N GLY 59.A O no hydrogen 2.740 N/A ALA 31.A N THR 34.A O no hydrogen 3.100 N/A THR 34.A N ALA 31.A O no hydrogen 2.920 N/A LEU 35.A N VAL 50.A O no hydrogen 2.841 N/A SER 36.A N GLN 29.A O no hydrogen 2.922 N/A LEU 37.A N ALA 48.A O no hydrogen 2.744 N/A THR 38.A N LEU 27.A O no hydrogen 2.999 N/A GLY 39.A N MET 46.A O no hydrogen 2.929 N/A THR 40.A OG1 MET 44.A O no hydrogen 2.785 N/A ASP 41.A N MET 44.A O no hydrogen 3.249 N/A GLU 43.A N ASP 41.A OD1 no hydrogen 2.967 N/A MET 44.A N ASP 41.A OD1 no hydrogen 2.807 N/A GLU 45.A N THR 226.A O no hydrogen 2.816 N/A MET 46.A N GLY 39.A O no hydrogen 3.016 N/A VAL 47.A N ILE 224.A O no hydrogen 2.865 N/A ALA 48.A N LEU 37.A O no hydrogen 2.824 N/A ARG 49.A N ASP 222.A O no hydrogen 3.029 N/A ARG 49.A NE SER 36.A OG no hydrogen 3.425 N/A VAL 50.A N LEU 35.A O no hydrogen 2.882 N/A LEU 52.A N GLY 33.A O no hydrogen 3.049 N/A HIS 56.A ND1 GLN 54.A O no hydrogen 2.939 N/A GLU 57.A N LYS 2.A O no hydrogen 2.890 N/A GLY 59.A N VAL 30.A O no hydrogen 3.095 N/A THR 61.A N LEU 28.A O no hydrogen 2.976 N/A THR 61.A OG1 THR 62.A O no hydrogen 3.503 N/A THR 62.A OG1 LEU 104.A O no hydrogen 2.641 N/A VAL 63.A N LEU 26.A O no hydrogen 3.121 N/A ALA 65.A N GLY 24.A O no hydrogen 2.912 N/A PHE 68.A N PRO 64.A O no hydrogen 3.049 N/A PHE 69.A N ALA 65.A O no hydrogen 3.078 N/A ASP 70.A N ARG 66.A O no hydrogen 2.898 N/A ILE 71.A N LYS 67.A O no hydrogen 3.225 N/A CYS 72.A N PHE 68.A O no hydrogen 3.287 N/A CYS 72.A SG PHE 68.A O no hydrogen 3.299 N/A ARG 73.A N PHE 69.A O no hydrogen 2.956 N/A GLY 74.A N ASP 70.A O no hydrogen 2.775 N/A LEU 75.A N CYS 72.A O no hydrogen 3.285 N/A GLY 78.A N GLU 8.A OE1 no hydrogen 3.223 N/A GLY 78.A N GLU 8.A OE2 no hydrogen 3.056 N/A ALA 79.A N PRO 76.A O no hydrogen 3.199 N/A ILE 81.A N VAL 5.A O no hydrogen 2.844 N/A ALA 82.A N ARG 93.A O no hydrogen 2.856 N/A VAL 83.A N PHE 3.A O no hydrogen 2.816 N/A GLN 84.A N LEU 91.A O no hydrogen 3.012 N/A GLN 84.A NE2 GLU 86.A OE2 no hydrogen 2.755 N/A GLU 86.A N ARG 89.A O no hydrogen 3.089 N/A MET 90.A N LEU 101.A O no hydrogen 2.755 N/A LEU 91.A N GLN 84.A O no hydrogen 2.736 N/A VAL 92.A N PHE 99.A O no hydrogen 2.733 N/A ARG 93.A N ALA 82.A O no hydrogen 2.813 N/A SER 94.A N SER 97.A O no hydrogen 3.125 N/A SER 94.A OG GLU 80.A O no hydrogen 3.202 N/A SER 97.A N SER 94.A O no hydrogen 2.797 N/A PHE 99.A N VAL 92.A O no hydrogen 2.811 N/A LEU 101.A N MET 90.A O no hydrogen 2.895 N/A THR 103.A N GLU 88.A O no hydrogen 3.332 N/A THR 103.A OG1 GLU 88.A O no hydrogen 2.915 N/A LEU 104.A N THR 62.A O no hydrogen 3.425 N/A ASP 108.A N PRO 105.A O no hydrogen 3.027 N/A SER 117.A OG GLU 120.A OE2 no hydrogen 3.384 N/A GLU 118.A N ILE 211.A O no hydrogen 2.807 N/A VAL 119.A N ILE 211.A O no hydrogen 3.050 N/A PHE 121.A N VAL 209.A O no hydrogen 3.099 N/A THR 122.A N GLN 179.A OE1 no hydrogen 3.434 N/A LEU 123.A N LEU 207.A O no hydrogen 3.083 N/A GLN 125.A NE2 ASN 205.A O no hydrogen 2.797 N/A THR 127.A N PRO 124.A O no hydrogen 3.237 N/A LYS 129.A N GLN 125.A O no hydrogen 2.965 N/A LYS 129.A NZ GLU 133.A OE2 no hydrogen 3.332 N/A ARG 130.A N ALA 126.A O no hydrogen 3.068 N/A LEU 131.A N THR 127.A O no hydrogen 3.353 N/A ILE 132.A N MET 128.A O no hydrogen 3.207 N/A GLU 133.A N LYS 129.A O no hydrogen 3.058 N/A ALA 134.A N ARG 130.A O no hydrogen 2.919 N/A THR 135.A N ILE 132.A O no hydrogen 3.136 N/A THR 135.A OG1 LEU 131.A O no hydrogen 3.181 N/A THR 135.A OG1 THR 162.A OG1 no hydrogen 3.151 N/A GLN 136.A N ILE 132.A O no hydrogen 2.806 N/A SER 138.A N THR 135.A O no hydrogen 3.008 N/A MET 139.A N GLN 136.A O no hydrogen 3.184 N/A ALA 140.A N LEU 148.A O no hydrogen 3.013 N/A ARG 145.A N ASP 143.A OD2 no hydrogen 3.056 N/A ARG 145.A NE ASP 143.A OD2 no hydrogen 3.035 N/A ARG 145.A NH2 ASP 143.A OD1 no hydrogen 3.566 N/A TYR 146.A N VAL 144.A O no hydrogen 2.946 N/A LEU 148.A N ARG 145.A O no hydrogen 3.003 N/A ASN 149.A N TYR 146.A O no hydrogen 3.166 N/A MET 151.A N VAL 188.A O no hydrogen 2.750 N/A LEU 152.A N VAL 163.A O no hydrogen 2.942 N/A PHE 153.A N VAL 186.A O no hydrogen 2.740 N/A GLU 154.A N ARG 161.A O no hydrogen 2.815 N/A THR 155.A N HIS 184.A O no hydrogen 2.935 N/A THR 155.A OG1 PRO 182.A O no hydrogen 2.750 N/A THR 155.A OG1 HIS 184.A O no hydrogen 3.415 N/A GLU 156.A N GLU 159.A O no hydrogen 3.124 N/A GLU 159.A N GLU 156.A O no hydrogen 3.112 N/A LEU 160.A N MET 175.A O no hydrogen 3.007 N/A ARG 161.A N GLU 154.A O no hydrogen 2.711 N/A THR 162.A N CYS 173.A O no hydrogen 2.870 N/A THR 162.A OG1 LEU 131.A O no hydrogen 2.680 N/A THR 162.A OG1 THR 135.A OG1 no hydrogen 3.151 N/A VAL 163.A N LEU 152.A O no hydrogen 3.103 N/A ALA 164.A N ALA 171.A O no hydrogen 3.059 N/A THR 165.A OG1 ARG 169.A O no hydrogen 2.608 N/A ASP 166.A N ARG 169.A O no hydrogen 3.302 N/A GLY 167.A N THR 165.A OG1 no hydrogen 3.293 N/A ARG 169.A N ASP 166.A OD1 no hydrogen 3.187 N/A ARG 169.A NE ASP 166.A OD1 no hydrogen 3.194 N/A ARG 169.A NE ASP 166.A OD2 no hydrogen 3.419 N/A ARG 169.A NH1 ASP 317.A OD2 no hydrogen 3.322 N/A LEU 170.A N VAL 351.A O no hydrogen 2.794 N/A ALA 171.A N ALA 164.A O no hydrogen 2.853 N/A VAL 172.A N ALA 349.A O no hydrogen 2.920 N/A CYS 173.A N THR 162.A O no hydrogen 2.965 N/A CYS 173.A SG SER 347.A O no hydrogen 4.015 N/A SER 174.A N SER 347.A O no hydrogen 2.943 N/A MET 175.A N LEU 160.A O no hydrogen 2.896 N/A ILE 177.A N GLU 158.A O no hydrogen 2.815 N/A GLN 179.A NE2 THR 122.A O no hydrogen 2.866 N/A LEU 181.A N GLY 157.A O no hydrogen 2.770 N/A HIS 184.A N THR 155.A O no hydrogen 3.271 N/A VAL 186.A N PHE 153.A O no hydrogen 2.858 N/A VAL 188.A N MET 151.A O no hydrogen 2.751 N/A ARG 190.A NH1 ALA 140.A O no hydrogen 2.593 N/A ARG 190.A NH2 MET 139.A O no hydrogen 3.532 N/A GLY 192.A N PRO 189.A O no hydrogen 3.061 N/A VAL 193.A N PRO 189.A O no hydrogen 3.065 N/A ILE 194.A N ARG 190.A O no hydrogen 3.073 N/A GLU 195.A N LYS 191.A O no hydrogen 3.310 N/A LEU 196.A N GLY 192.A O no hydrogen 2.738 N/A MET 197.A N VAL 193.A O no hydrogen 3.126 N/A ARG 198.A N ILE 194.A O no hydrogen 2.958 N/A ARG 198.A NH2 GLN 15.A O no hydrogen 2.634 N/A MET 199.A N GLU 195.A O no hydrogen 3.022 N/A LEU 200.A N MET 197.A O no hydrogen 3.057 N/A ASP 201.A N GLN 125.A OE1 no hydrogen 3.209 N/A GLY 202.A N GLN 125.A OE1 no hydrogen 3.074 N/A LEU 207.A N LEU 123.A O no hydrogen 2.893 N/A ARG 208.A N HIS 219.A O no hydrogen 2.789 N/A VAL 209.A N PHE 121.A O no hydrogen 2.983 N/A GLN 210.A N ARG 217.A O no hydrogen 2.883 N/A GLN 210.A NE2 GLU 120.A OE2 no hydrogen 2.794 N/A ILE 211.A N VAL 119.A O no hydrogen 2.775 N/A GLY 212.A N ASN 215.A O no hydrogen 2.854 N/A SER 213.A OG ASN 214.A OD1 no hydrogen 3.385 N/A ILE 216.A N SER 227.A O no hydrogen 2.993 N/A ARG 217.A N GLN 210.A O no hydrogen 2.779 N/A ARG 217.A NE THR 226.A OG1 no hydrogen 3.164 N/A ALA 218.A N PHE 225.A O no hydrogen 2.786 N/A HIS 219.A N ARG 208.A O no hydrogen 2.820 N/A HIS 219.A NE2 GLN 210.A OE1 no hydrogen 3.001 N/A VAL 220.A N PHE 223.A O no hydrogen 3.178 N/A PHE 223.A N VAL 220.A O no hydrogen 2.978 N/A ILE 224.A N VAL 47.A O no hydrogen 2.803 N/A PHE 225.A N ALA 218.A O no hydrogen 2.836 N/A THR 226.A N GLU 45.A O no hydrogen 2.791 N/A SER 227.A N ILE 216.A O no hydrogen 2.961 N/A SER 227.A OG LYS 228.A O no hydrogen 2.956 N/A LYS 228.A N GLU 43.A O no hydrogen 3.061 N/A LEU 229.A N ASN 214.A O no hydrogen 2.918 N/A VAL 230.A N ILE 187.A O no hydrogen 2.823 N/A GLY 232.A N VAL 230.A O no hydrogen 3.094 N/A TYR 237.A OH GLU 154.A OE2 no hydrogen 2.711 N/A ARG 238.A NH1 GLU 154.A OE1 no hydrogen 3.383 N/A VAL 240.A N TYR 237.A O no hydrogen 2.844 N/A LEU 241.A N ARG 238.A O no hydrogen 3.388 N/A LYS 245.A N LEU 331.A O no hydrogen 2.890 N/A LYS 245.A NZ ASP 244.A OD2 no hydrogen 2.990 N/A LYS 245.A NZ THR 332.A O no hydrogen 2.759 N/A LEU 247.A N MET 329.A O no hydrogen 2.872 N/A GLU 248.A N THR 300.A O no hydrogen 2.980 N/A ALA 249.A N VAL 327.A O no hydrogen 3.121 N/A CYS 251.A N GLU 325.A O no hydrogen 2.718 N/A CYS 251.A SG LEU 319.A O no hydrogen 3.905 N/A CYS 251.A SG LEU 322.A O no hydrogen 3.621 N/A LEU 254.A N GLY 250.A O no hydrogen 3.235 N/A LYS 255.A N CYS 251.A O no hydrogen 2.979 N/A GLN 256.A N ASP 252.A O no hydrogen 2.911 N/A GLN 256.A NE2 ASP 252.A OD2 no hydrogen 3.128 N/A ALA 257.A N LEU 253.A O no hydrogen 3.124 N/A PHE 258.A N LEU 254.A O no hydrogen 3.151 N/A ALA 259.A N LYS 255.A O no hydrogen 3.168 N/A ARG 260.A N GLN 256.A O no hydrogen 3.184 N/A ARG 260.A NE GLU 295.A OE2 no hydrogen 2.519 N/A ARG 260.A NH2 GLU 295.A OE1 no hydrogen 3.129 N/A ALA 261.A N ALA 257.A O no hydrogen 3.132 N/A ALA 262.A N PHE 258.A O no hydrogen 2.991 N/A ILE 263.A N ARG 260.A O no hydrogen 3.352 N/A LEU 264.A N ALA 261.A O no hydrogen 3.246 N/A SER 265.A N ALA 262.A O no hydrogen 3.211 N/A SER 265.A OG ALA 262.A O no hydrogen 2.631 N/A LYS 268.A N ASN 266.A OD1 no hydrogen 3.173 N/A PHE 269.A N ASN 266.A OD1 no hydrogen 3.117 N/A ARG 270.A N ASN 266.A O no hydrogen 2.817 N/A ARG 270.A NE SER 313.A OG no hydrogen 3.208 N/A VAL 272.A N PHE 310.A O no hydrogen 2.882 N/A ARG 273.A N THR 284.A O no hydrogen 2.814 N/A LEU 274.A N ILE 308.A O no hydrogen 2.922 N/A TYR 275.A N LYS 282.A O no hydrogen 2.680 N/A VAL 276.A N MET 306.A O no hydrogen 2.977 N/A SER 277.A N GLN 280.A O no hydrogen 3.072 N/A ASN 279.A N TYR 301.A O no hydrogen 2.905 N/A ASN 279.A ND2 TYR 301.A O no hydrogen 2.860 N/A GLN 280.A N SER 277.A O no hydrogen 2.710 N/A LEU 281.A N LEU 297.A O no hydrogen 3.004 N/A LYS 282.A N TYR 275.A O no hydrogen 2.859 N/A ILE 283.A N GLU 295.A O no hydrogen 2.833 N/A THR 284.A N ARG 273.A O no hydrogen 2.828 N/A ALA 285.A N ALA 293.A O no hydrogen 3.185 N/A ASN 286.A ND2 GLU 292.A OE2 no hydrogen 3.396 N/A ASN 287.A ND2 GLU 291.A OE1 no hydrogen 3.005 N/A GLN 290.A N ASN 287.A O no hydrogen 3.193 N/A GLU 291.A N ASN 287.A OD1 no hydrogen 3.063 N/A ALA 293.A N ALA 285.A O no hydrogen 3.051 N/A GLU 295.A N ILE 283.A O no hydrogen 2.916 N/A LEU 297.A N LEU 281.A O no hydrogen 2.824 N/A VAL 299.A N ASN 279.A O no hydrogen 3.124 N/A THR 300.A N GLU 248.A O no hydrogen 2.836 N/A TYR 301.A OH ALA 304.A O no hydrogen 2.374 N/A MET 306.A N VAL 276.A O no hydrogen 3.041 N/A ILE 308.A N LEU 274.A O no hydrogen 3.051 N/A PHE 310.A N VAL 272.A O no hydrogen 3.033 N/A VAL 312.A N ARG 270.A O no hydrogen 2.816 N/A SER 313.A N ASN 311.A OD1 no hydrogen 2.781 N/A TYR 314.A N ASN 311.A O no hydrogen 3.181 N/A TYR 314.A N ASN 311.A OD1 no hydrogen 3.376 N/A VAL 315.A N ASN 311.A O no hydrogen 3.407 N/A LEU 316.A N VAL 312.A O no hydrogen 3.099 N/A ASP 317.A N SER 313.A O no hydrogen 2.925 N/A VAL 318.A N TYR 314.A O no hydrogen 3.313 N/A LEU 319.A N VAL 315.A O no hydrogen 3.055 N/A ASN 320.A N LEU 316.A O no hydrogen 2.765 N/A ALA 321.A N ASP 317.A O no hydrogen 3.080 N/A LEU 322.A N LEU 319.A O no hydrogen 3.313 N/A CYS 324.A SG ASN 326.A O no hydrogen 3.536 N/A VAL 327.A N ALA 249.A O no hydrogen 2.793 N/A ARG 328.A N GLU 341.A O no hydrogen 2.764 N/A MET 329.A N LEU 247.A O no hydrogen 2.929 N/A MET 330.A N GLN 339.A O no hydrogen 2.694 N/A LEU 331.A N LYS 245.A O no hydrogen 2.707 N/A VAL 335.A N ASP 333.A OD1 no hydrogen 3.017 N/A SER 336.A OG ASP 333.A OD1 no hydrogen 2.602 N/A SER 336.A OG ASP 333.A OD2 no hydrogen 3.327 N/A VAL 338.A N VAL 352.A O no hydrogen 3.036 N/A GLN 339.A N MET 330.A O no hydrogen 3.001 N/A ILE 340.A N TYR 350.A O no hydrogen 2.732 N/A GLU 341.A N ARG 328.A O no hydrogen 2.948 N/A ALA 343.A N ASN 326.A O no hydrogen 3.036 N/A ALA 344.A N ASP 342.A OD1 no hydrogen 2.970 N/A SER 345.A N ASP 342.A O no hydrogen 3.510 N/A SER 345.A OG SER 347.A OG no hydrogen 2.926 N/A SER 347.A OG SER 345.A OG no hydrogen 2.926 N/A ALA 349.A N VAL 172.A O no hydrogen 2.873 N/A TYR 350.A N ILE 340.A O no hydrogen 3.024 N/A TYR 350.A OH ALA 134.A O no hydrogen 2.630 N/A VAL 351.A N LEU 170.A O no hydrogen 2.958 N/A VAL 352.A N VAL 338.A O no hydrogen 3.043 N/A MET 353.A N HIS 168.A O no hydrogen 3.023 N/A MET 355.A N GLY 309.A O no hydrogen 3.155 N/A