Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3r4v_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 2.A N GLU 76.A O no hydrogen 3.195 N/A CYS 5.A N PHE 79.A O no hydrogen 2.996 N/A CYS 5.A SG.B PRO 75.A O no hydrogen 3.714 N/A LEU 6.A N ALA 26.A O no hydrogen 2.828 N/A ILE 7.A N ILE 81.A O no hydrogen 2.680 N/A PHE 8.A N HIS 28.A O no hydrogen 2.863 N/A ALA 9.A N CYS 83.A O no hydrogen 2.979 N/A GLY 10.A N PHE 30.A O no hydrogen 2.987 N/A MET 14.A N GLY 10.A O no hydrogen 2.924 N/A ASN 15.A N GLY 11.A O no hydrogen 2.837 N/A VAL 16.A N THR 12.A O no hydrogen 2.898 N/A ALA 17.A N GLY 13.A O no hydrogen 2.915 N/A THR 18.A N MET 14.A O no hydrogen 3.294 N/A THR 18.A N ASN 15.A O no hydrogen 3.326 N/A THR 18.A OG1 ASN 15.A O no hydrogen 2.740 N/A LYS 19.A N VAL 16.A O no hydrogen 3.002 N/A LYS 19.A NZ GLU 158.A OE2 no hydrogen 2.761 N/A LEU 20.A N ALA 17.A O no hydrogen 2.757 N/A LEU 23.A N LEU 20.A O no hydrogen 2.941 N/A GLY 24.A N VAL 21.A O no hydrogen 2.944 N/A ALA 26.A N LEU 23.A O no hydrogen 3.238 N/A VAL 27.A N GLY 24.A O no hydrogen 2.874 N/A HIS 28.A N LEU 6.A O no hydrogen 2.692 N/A CYS 29.A N ASN 45.A O no hydrogen 2.811 N/A PHE 30.A N PHE 8.A O no hydrogen 2.782 N/A ASP 31.A N THR 47.A O no hydrogen 3.285 N/A THR 32.A N ASP 31.A OD2 no hydrogen 2.829 N/A THR 32.A OG1 SER 90.A OG no hydrogen 2.678 N/A CYS 33.A SG.A ASP 34.A OD1 no hydrogen 3.565 N/A ASN 36.A ND2 ASN 15.A OD1 no hydrogen 2.888 N/A VAL 37.A N ASP 34.A O no hydrogen 3.188 N/A VAL 38.A N HIS 41.A ND1 no hydrogen 3.034 N/A HIS 41.A N VAL 38.A O no hydrogen 3.027 N/A HIS 41.A NE2 MET 14.A O no hydrogen 3.015 N/A ARG 42.A N.A ASP 39.A O.A no hydrogen 2.978 N/A ARG 42.A N.A ASP 39.A O.B no hydrogen 3.092 N/A ARG 42.A N.B ASP 39.A O.A no hydrogen 2.973 N/A ARG 42.A N.B ASP 39.A O.B no hydrogen 3.087 N/A SER 43.A N VAL 40.A O no hydrogen 3.184 N/A VAL 44.A N HIS 41.A O no hydrogen 2.915 N/A ASN 45.A N VAL 27.A O no hydrogen 3.082 N/A ASN 45.A ND2 VAL 27.A O no hydrogen 3.057 N/A THR 47.A N CYS 29.A O no hydrogen 2.871 N/A THR 49.A N ASP 31.A O no hydrogen 2.968 N/A THR 49.A OG1 ASP 31.A O no hydrogen 3.526 N/A THR 49.A OG1 THR 52.A OG1 no hydrogen 2.689 N/A LYS 50.A N GLN 66.A OE1 no hydrogen 2.756 N/A THR 52.A OG1 THR 32.A O no hydrogen 2.714 N/A THR 52.A OG1 THR 49.A O no hydrogen 3.251 N/A THR 52.A OG1 THR 49.A OG1 no hydrogen 2.689 N/A ARG 56.A NE SER 92.A O no hydrogen 3.395 N/A ARG 56.A NE SER 92.A OG no hydrogen 2.833 N/A ARG 56.A NH2 SER 92.A O no hydrogen 2.991 N/A ARG 56.A NH2 THR 132.A OG1 no hydrogen 3.427 N/A VAL 58.A N ASN 55.A OD1 no hydrogen 3.135 N/A ILE 59.A N ASN 55.A O no hydrogen 3.086 N/A LEU 60.A N ARG 56.A O no hydrogen 2.934 N/A LEU 62.A N ILE 59.A O no hydrogen 3.127 N/A VAL 63.A N ILE 59.A O no hydrogen 3.083 N/A VAL 63.A N LEU 60.A O no hydrogen 3.248 N/A ARG 64.A N LEU 60.A O no hydrogen 2.924 N/A ARG 64.A NH1 ARG 64.A O no hydrogen 3.069 N/A GLN 66.A N VAL 63.A O no hydrogen 2.870 N/A GLN 66.A NE2 LYS 50.A O no hydrogen 3.031 N/A GLN 66.A NE2 LEU 62.A O no hydrogen 2.891 N/A ILE 67.A N ARG 64.A O no hydrogen 3.204 N/A LEU 70.A N GLN 66.A O no hydrogen 3.040 N/A MET 71.A N ILE 67.A O no hydrogen 2.839 N/A ASP 72.A N PRO 68.A O no hydrogen 3.188 N/A THR 73.A N LEU 70.A O no hydrogen 3.115 N/A THR 73.A OG1 LEU 70.A O no hydrogen 2.778 N/A ILE 74.A N MET 71.A O no hydrogen 2.994 N/A ALA 77.A N TYR 80.A OH no hydrogen 2.948 N/A ASP 78.A N VAL 2.A O no hydrogen 2.933 N/A TYR 80.A N SER 108.A O no hydrogen 3.007 N/A ILE 81.A N CYS 5.A O no hydrogen 2.953 N/A VAL 82.A N VAL 110.A O no hydrogen 2.995 N/A CYS 83.A N ILE 7.A O no hydrogen 2.826 N/A CYS 83.A SG PHE 112.A O no hydrogen 3.726 N/A TYR 84.A N PHE 112.A O no hydrogen 3.159 N/A LEU 86.A N VAL 114.A O no hydrogen 2.902 N/A GLY 87.A N SER 85.A OG no hydrogen 3.197 N/A SER 90.A OG THR 32.A OG1 no hydrogen 2.678 N/A SER 92.A OG GLY 88.A O no hydrogen 2.666 N/A VAL 93.A N SER 90.A O no hydrogen 3.155 N/A LEU 94.A N SER 90.A O no hydrogen 2.783 N/A GLY 95.A N GLY 91.A O no hydrogen 2.806 N/A LEU 97.A N VAL 93.A O no hydrogen 3.078 N/A ILE 98.A N LEU 94.A O no hydrogen 2.929 N/A THR 99.A N GLY 95.A O no hydrogen 2.920 N/A THR 99.A OG1 GLY 95.A O no hydrogen 2.751 N/A GLY 100.A N PRO 96.A O no hydrogen 2.878 N/A GLN 101.A N LEU 97.A O no hydrogen 3.118 N/A LEU 102.A N ILE 98.A O no hydrogen 2.834 N/A ALA 103.A N THR 99.A O no hydrogen 2.910 N/A ASP 104.A N GLY 100.A O no hydrogen 3.072 N/A ARG 105.A N GLN 101.A O no hydrogen 3.072 N/A ARG 105.A NH1 ILE 74.A O no hydrogen 3.188 N/A ARG 105.A NH1 PRO 75.A O no hydrogen 3.286 N/A ARG 105.A NH1 TYR 80.A OH no hydrogen 3.106 N/A ARG 105.A NH2 ILE 74.A O no hydrogen 2.975 N/A LYS 106.A N ALA 103.A O no hydrogen 2.845 N/A ALA 107.A N LEU 102.A O no hydrogen 3.147 N/A VAL 110.A N TYR 80.A O no hydrogen 3.203 N/A SER 111.A N VAL 145.A O no hydrogen 2.935 N/A PHE 112.A N VAL 82.A O no hydrogen 2.698 N/A VAL 113.A N ASN 147.A O no hydrogen 2.995 N/A VAL 114.A N TYR 84.A O no hydrogen 3.178 N/A GLY 115.A N VAL 149.A O no hydrogen 2.804 N/A ALA 116.A N ASP 126.A OD1 no hydrogen 3.221 N/A GLU 118.A N ASN 122.A OD1 no hydrogen 3.145 N/A ASN 122.A N SER 119.A OG no hydrogen 3.091 N/A ASN 122.A ND2 GLY 87.A O no hydrogen 3.096 N/A LEU 123.A N SER 119.A O no hydrogen 3.057 N/A GLY 124.A N THR 120.A O no hydrogen 2.826 N/A ASN 125.A N ASP 121.A O no hydrogen 2.906 N/A ASN 125.A ND2 GLY 54.A O no hydrogen 3.268 N/A ASN 125.A ND2 GLY 87.A O no hydrogen 3.021 N/A ASP 126.A N ASN 122.A O no hydrogen 2.804 N/A ILE 127.A N LEU 123.A O no hydrogen 3.093 N/A ASP 128.A N GLY 124.A O no hydrogen 3.015 N/A THR 129.A N ASN 125.A O no hydrogen 2.838 N/A THR 129.A OG1 LEU 86.A O no hydrogen 3.089 N/A THR 129.A OG1 ASN 125.A O no hydrogen 2.808 N/A MET 130.A N ASP 126.A O no hydrogen 2.956 N/A LYS 131.A N ILE 127.A O no hydrogen 2.936 N/A THR 132.A N ASP 128.A O no hydrogen 2.830 N/A THR 132.A OG1 ASP 128.A O no hydrogen 2.876 N/A LEU 133.A N THR 129.A O no hydrogen 2.938 N/A GLU 134.A N MET 130.A O no hydrogen 2.980 N/A ALA 135.A N LYS 131.A O no hydrogen 2.817 N/A ILE 136.A N THR 132.A O no hydrogen 2.912 N/A ALA 137.A N LEU 133.A O no hydrogen 2.867 N/A VAL 138.A N GLU 134.A O no hydrogen 2.994 N/A ASN 139.A N ALA 135.A O no hydrogen 2.791 N/A LYS 140.A N ILE 136.A O no hydrogen 2.851 N/A LYS 140.A NZ ASP 104.A OD1 no hydrogen 2.847 N/A LYS 140.A NZ ASP 104.A OD2 no hydrogen 3.362 N/A HIS 141.A N VAL 138.A O no hydrogen 3.187 N/A LEU 142.A N ALA 137.A O no hydrogen 2.967 N/A ILE 144.A N GLN 203.A O no hydrogen 3.182 N/A VAL 146.A N CYS 205.A O no hydrogen 2.827 N/A ASN 147.A N SER 111.A O no hydrogen 2.794 N/A ASN 147.A ND2 LEU 207.A O no hydrogen 2.860 N/A VAL 149.A N VAL 113.A O no hydrogen 2.943 N/A ASN 151.A N GLY 115.A O no hydrogen 2.857 N/A ARG 155.A N.A THR 152.A O no hydrogen 3.139 N/A ARG 155.A N.B THR 152.A O no hydrogen 3.187 N/A ARG 155.A NE.A SER 159.A OG no hydrogen 2.862 N/A ARG 155.A NH1.A GLU 163.A OE2 no hydrogen 2.973 N/A ARG 155.A NH2.A SER 159.A OG no hydrogen 3.375 N/A ARG 155.A NH2.A GLU 163.A OE2 no hydrogen 2.740 N/A TYR 157.A OH GLU 118.A OE2 no hydrogen 2.667 N/A SER 159.A N SER 156.A OG no hydrogen 2.875 N/A ILE 160.A N SER 156.A O no hydrogen 3.107 N/A ASN 161.A N TYR 157.A O no hydrogen 2.804 N/A ASP 162.A N GLU 158.A O no hydrogen 2.950 N/A GLU 163.A N SER 159.A O no hydrogen 3.071 N/A ILE 164.A N ILE 160.A O no hydrogen 3.005 N/A ALA 165.A N ASN 161.A O no hydrogen 2.934 N/A GLU 166.A N.A ASP 162.A O no hydrogen 3.040 N/A GLU 166.A N.B ASP 162.A O no hydrogen 3.062 N/A LYS 167.A N GLU 163.A O no hydrogen 3.082 N/A LYS 167.A NZ ASN 147.A OD1 no hydrogen 2.993 N/A LYS 167.A NZ GLU 163.A OE1 no hydrogen 2.850 N/A ILE 168.A N ILE 164.A O no hydrogen 2.886 N/A ARG 169.A N ALA 165.A O no hydrogen 3.012 N/A ARG 169.A NH1 ASP 22.A OD2 no hydrogen 3.065 N/A ARG 169.A NH2 ASP 22.A OD1 no hydrogen 2.701 N/A LYS 170.A N GLU 166.A O.A no hydrogen 3.207 N/A LYS 170.A N GLU 166.A O.B no hydrogen 3.317 N/A LYS 170.A NZ ASP 258.A OD1 no hydrogen 3.556 N/A VAL 171.A N LYS 167.A O no hydrogen 3.118 N/A VAL 172.A N ILE 168.A O no hydrogen 2.816 N/A LEU 173.A N ARG 169.A O no hydrogen 2.880 N/A LEU 174.A N LYS 170.A O no hydrogen 2.833 N/A VAL 175.A N VAL 171.A O no hydrogen 3.039 N/A ASN 176.A N LEU 173.A O no hydrogen 3.083 N/A ASN 176.A ND2 ASP 253.A OD2 no hydrogen 3.073 N/A GLN 177.A NE2 ASP 78.A OD2 no hydrogen 2.940 N/A ASN 178.A N ASN 176.A OD1 no hydrogen 2.873 N/A ASN 178.A ND2 ASP 253.A OD2 no hydrogen 3.297 N/A HIS 179.A NE2 LEU 173.A O no hydrogen 2.783 N/A GLY 180.A N ILE 248.A O no hydrogen 2.911 N/A ARG 181.A NH1 GLU 235.A OE1 no hydrogen 3.153 N/A ARG 181.A NH2 GLU 235.A OE1 no hydrogen 3.312 N/A ARG 181.A NH2 GLU 235.A OE2 no hydrogen 3.113 N/A LEU 182.A N HIS 179.A O no hydrogen 3.433 N/A ASP 183.A N.A ASP 186.A OD2 no hydrogen 2.771 N/A ASP 183.A N.B ASP 186.A OD2 no hydrogen 2.794 N/A HIS 185.A ND1 ASP 183.A OD2.B no hydrogen 2.777 N/A VAL 187.A N ASP 183.A O.A no hydrogen 3.269 N/A VAL 187.A N ASP 183.A O.B no hydrogen 3.157 N/A ALA 188.A N VAL 184.A O no hydrogen 3.005 N/A ASN 189.A N HIS 185.A O no hydrogen 2.945 N/A ASN 189.A ND2 HIS 185.A O no hydrogen 3.022 N/A TRP 190.A N ASP 186.A O no hydrogen 3.030 N/A TRP 190.A N VAL 187.A O no hydrogen 3.112 N/A VAL 191.A N VAL 187.A O no hydrogen 3.175 N/A ARG 192.A N ALA 188.A O no hydrogen 2.813 N/A ARG 192.A NE ASP 195.A OD2 no hydrogen 2.850 N/A ARG 192.A NH1 ALA 107.A O no hydrogen 2.930 N/A ARG 192.A NH2 ASP 195.A OD1 no hydrogen 3.407 N/A ARG 192.A NH2 ASP 195.A OD2 no hydrogen 3.391 N/A ASP 195.A N ARG 192.A O no hydrogen 3.018 N/A HIS 197.A N PHE 193.A O no hydrogen 3.128 N/A ASN 198.A ND2.A ASP 195.A O no hydrogen 3.631 N/A TYR 199.A OH HIS 197.A ND1 no hydrogen 2.987 N/A LEU 200.A N HIS 197.A O no hydrogen 3.109 N/A VAL 204.A N GLU 134.A OE1 no hydrogen 2.840 N/A CYS 205.A N ILE 144.A O no hydrogen 2.926 N/A CYS 205.A SG GLN 203.A O no hydrogen 3.537 N/A GLU 206.A N ASN 266.A O no hydrogen 2.790 N/A LEU 207.A N VAL 146.A O no hydrogen 2.787 N/A HIS 208.A N VAL 264.A O no hydrogen 2.763 N/A HIS 208.A NE2 ASN 266.A OD1 no hydrogen 2.836 N/A GLU 210.A N HIS 262.A O no hydrogen 2.878 N/A THR 212.A OG1 ASP 215.A OD2 no hydrogen 2.632 N/A ARG 213.A NE GLU 217.A OE2 no hydrogen 2.924 N/A ARG 213.A NH2 GLU 217.A OE2 no hydrogen 3.257 N/A ASP 215.A N THR 212.A OG1 no hydrogen 3.020 N/A ALA 216.A N THR 212.A O no hydrogen 3.256 N/A GLU 217.A N ARG 213.A O no hydrogen 2.815 N/A ASN 218.A N LYS 214.A O no hydrogen 3.177 N/A ASN 218.A N ASP 215.A O no hydrogen 3.249 N/A VAL 219.A N ALA 216.A O no hydrogen 3.176 N/A ILE 223.A N ILE 265.A O no hydrogen 2.779 N/A SER 224.A N ILE 265.A O no hydrogen 3.273 N/A SER 224.A OG TRP 190.A O no hydrogen 2.743 N/A GLN 225.A N TYR 243.A O no hydrogen 2.845 N/A GLN 225.A NE2 PHE 238.A O no hydrogen 3.332 N/A LEU 226.A N PHE 263.A O no hydrogen 2.962 N/A SER 227.A N LYS 245.A O no hydrogen 2.888 N/A SER 227.A OG HIS 262.A ND1 no hydrogen 2.653 N/A LEU 228.A N ILE 261.A O no hydrogen 2.752 N/A TYR 229.A N GLY 247.A O no hydrogen 2.972 N/A LEU 230.A N ASP 259.A O no hydrogen 2.849 N/A SER 233.A N ASP 231.A OD1 no hydrogen 2.945 N/A SER 233.A OG ASP 231.A OD1 no hydrogen 2.748 N/A SER 233.A OG ASP 231.A OD2 no hydrogen 3.259 N/A LYS 234.A N ASP 231.A O no hydrogen 2.965 N/A LYS 234.A NZ ASP 259.A OD2 no hydrogen 2.849 N/A LYS 234.A NZ GLN 260.A OE1 no hydrogen 3.070 N/A GLU 235.A N PRO 232.A O no hydrogen 3.459 N/A VAL 236.A N TYR 229.A OH no hydrogen 3.485 N/A ILE 242.A N ILE 223.A O no hydrogen 2.846 N/A TYR 243.A N ILE 223.A O no hydrogen 3.150 N/A TYR 243.A OH ASP 186.A O no hydrogen 2.911 N/A ARG 244.A NH1.A PHE 238.A O no hydrogen 2.750 N/A ARG 244.A NH2.A PHE 238.A O no hydrogen 2.873 N/A ARG 244.A NH2.A GLY 239.A O no hydrogen 3.323 N/A LYS 245.A N GLN 225.A O no hydrogen 3.025 N/A LYS 245.A NZ ASP 186.A OD1 no hydrogen 3.192 N/A LYS 245.A NZ TYR 243.A OH no hydrogen 3.223 N/A GLY 247.A N SER 227.A O no hydrogen 2.812 N/A ILE 248.A N GLY 180.A O no hydrogen 2.942 N/A MET 249.A N TYR 229.A O no hydrogen 2.802 N/A LYS 250.A NZ ASN 178.A O no hydrogen 2.859 N/A ASP 253.A N LYS 250.A O no hydrogen 2.841 N/A ASP 255.A N ASP 253.A OD1 no hydrogen 3.163 N/A VAL 256.A N ASP 253.A O no hydrogen 3.012 N/A THR 257.A OG1 ASP 258.A OD1 no hydrogen 2.553 N/A GLN 260.A NE2 HIS 262.A NE2 no hydrogen 2.764 N/A ILE 261.A N LEU 228.A O no hydrogen 3.007 N/A HIS 262.A N GLU 210.A O no hydrogen 2.740 N/A HIS 262.A ND1 SER 227.A OG no hydrogen 2.653 N/A PHE 263.A N LEU 226.A O no hydrogen 2.745 N/A VAL 264.A N HIS 208.A O no hydrogen 2.810 N/A ILE 265.A N SER 224.A O no hydrogen 2.841 N/A ASN 266.A N GLU 206.A O no hydrogen 3.088 N/A ASN 266.A ND2 PRO 220.A O no hydrogen 2.774 N/A SER 267.A OG GLN 203.A OE1 no hydrogen 2.706 N/A VAL 270.A N SER 267.A O no hydrogen 3.198 N/A ILE 273.A N GLY 269.A O no hydrogen 3.132 N/A MET 274.A N VAL 270.A O no hydrogen 2.951 N/A LYS 275.A N VAL 271.A O no hydrogen 2.914 N/A LYS 275.A NZ ASP 279.A OD1 no hydrogen 3.010 N/A THR 276.A N GLU 272.A O no hydrogen 2.866 N/A THR 276.A OG1 GLU 272.A O no hydrogen 3.061 N/A ILE 277.A N.A ILE 273.A O no hydrogen 3.224 N/A ILE 277.A N.B ILE 273.A O no hydrogen 3.217 N/A THR 278.A N MET 274.A O no hydrogen 2.862 N/A THR 278.A OG1.A MET 274.A O no hydrogen 2.624 N/A THR 278.A OG1.B MET 274.A O no hydrogen 3.073 N/A THR 278.A OG1.B LYS 275.A O no hydrogen 3.275 N/A ASP 279.A N LYS 275.A O no hydrogen 2.845 N/A SER 280.A N THR 276.A O no hydrogen 3.024 N/A SER 280.A OG THR 276.A O no hydrogen 2.973 N/A LYS 281.A N ILE 277.A O.A no hydrogen 2.968 N/A LYS 281.A N ILE 277.A O.B no hydrogen 3.007 N/A LEU 282.A N THR 278.A O no hydrogen 2.857 N/A GLU 283.A N ASP 279.A O no hydrogen 2.970 N/A MET 284.A N SER 280.A O no hydrogen 2.991 N/A THR 285.A N LYS 281.A O no hydrogen 2.810 N/A THR 285.A OG1 LYS 281.A O no hydrogen 3.101 N/A ARG 286.A N LEU 282.A O no hydrogen 2.774 N/A ARG 286.A NE GLU 283.A OE1 no hydrogen 3.004 N/A ARG 286.A NH2 GLU 283.A OE1 no hydrogen 3.467 N/A ARG 286.A NH2 GLU 283.A OE2 no hydrogen 2.754 N/A GLN 287.A N GLU 283.A O no hydrogen 3.171 N/A GLN 287.A NE2 GLU 283.A OE2 no hydrogen 2.713 N/A GLN 288.A N MET 284.A O no hydrogen 3.009 N/A GLN 288.A NE2 THR 120.A OG1 no hydrogen 3.247 N/A SER 289.A N THR 285.A O no hydrogen 2.870 N/A SER 289.A OG THR 285.A O no hydrogen 3.449 N/A SER 289.A OG ARG 286.A O no hydrogen 3.049 N/A LYS 290.A N ARG 286.A O no hydrogen 3.002 N/A PHE 291.A N GLN 287.A O no hydrogen 3.178 N/A PHE 291.A N GLN 288.A O no hydrogen 3.308 N/A ARG 294.A NH1 ASN 295.A O no hydrogen 3.035 N/A ASP 299.A N ASP 302.A OD1 no hydrogen 2.880 N/A ASP 301.A N ASP 299.A OD2 no hydrogen 3.063 N/A ASP 302.A N ASP 299.A O no hydrogen 2.990 N/A ASP 305.A N MET 309.A O no hydrogen 3.011 N/A ASP 307.A N ASP 305.A OD1 no hydrogen 2.760 N/A GLY 308.A N ASP 305.A O no hydrogen 2.924 N/A MET 309.A N ASP 305.A OD1 no hydrogen 2.976 N/A