Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3r5x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A NE ASP 52.A OD2 no hydrogen 3.532 N/A ARG 4.A NH2 ASP 52.A OD1 no hydrogen 2.857 N/A ILE 5.A N GLU 33.A O no hydrogen 2.830 N/A GLY 6.A N PHE 53.A O no hydrogen 2.823 N/A VAL 7.A N VAL 35.A O no hydrogen 2.942 N/A ILE 8.A N LEU 55.A O no hydrogen 2.896 N/A SER 12.A OG VAL 11.A O no hydrogen 2.773 N/A LYS 15.A N VAL 11.A O no hydrogen 3.453 N/A GLN 16.A N SER 12.A O no hydrogen 3.267 N/A VAL 17.A N SER 13.A O no hydrogen 2.979 N/A SER 18.A N GLU 14.A O no hydrogen 2.832 N/A SER 18.A OG ALA 57.A O no hydrogen 2.829 N/A ILE 19.A N LYS 15.A O no hydrogen 2.813 N/A THR 20.A OG1 VAL 17.A O no hydrogen 2.918 N/A GLY 21.A N SER 18.A O no hydrogen 2.871 N/A ASN 22.A N ILE 19.A O no hydrogen 2.929 N/A ALA 25.A N ASN 22.A O no hydrogen 2.934 N/A ASN 26.A N GLU 23.A O no hydrogen 2.927 N/A ASN 26.A ND2 GLU 23.A O no hydrogen 2.773 N/A ASN 30.A N ASP 28.A OD1 no hydrogen 2.804 N/A LYS 31.A N ASP 28.A OD1 no hydrogen 3.143 N/A LYS 31.A NZ ASP 275.A OD2 no hydrogen 2.884 N/A TYR 32.A N ASP 28.A O no hydrogen 3.079 N/A TYR 32.A OH ASP 275.A OD1 no hydrogen 2.685 N/A VAL 35.A N ILE 5.A O no hydrogen 2.871 N/A ILE 37.A N VAL 7.A O no hydrogen 2.960 N/A GLU 41.A N ASP 43.A OD2 no hydrogen 2.795 N/A LEU 44.A N LYS 42.A O no hydrogen 3.211 N/A LYS 47.A N ASP 43.A O no hydrogen 3.115 N/A LYS 47.A NZ THR 38.A O no hydrogen 2.823 N/A ALA 48.A N LEU 44.A O no hydrogen 2.984 N/A LYS 49.A N GLU 46.A O no hydrogen 3.389 N/A ILE 51.A N ALA 48.A O no hydrogen 3.416 N/A ASP 52.A N ARG 4.A O no hydrogen 2.902 N/A PHE 53.A N ARG 4.A O no hydrogen 3.246 N/A ALA 54.A N PRO 78.A O no hydrogen 2.882 N/A LEU 55.A N GLY 6.A O no hydrogen 2.809 N/A LEU 56.A N SER 80.A OG no hydrogen 2.983 N/A ALA 57.A N ILE 8.A O no hydrogen 2.787 N/A LYS 61.A NZ ASP 65.A OD2 no hydrogen 3.052 N/A GLY 63.A N GLY 60.A O no hydrogen 2.949 N/A GLU 64.A N GLY 60.A O no hydrogen 3.078 N/A ASP 65.A N LYS 61.A O no hydrogen 2.956 N/A THR 67.A N ASP 65.A OD1 no hydrogen 3.036 N/A THR 67.A OG1 ASP 65.A OD1 no hydrogen 3.437 N/A GLN 69.A N GLN 69.A OE1 no hydrogen 2.769 N/A GLN 69.A NE2 GLY 63.A O no hydrogen 2.783 N/A GLY 70.A N GLY 66.A O no hydrogen 2.959 N/A THR 71.A N THR 67.A O no hydrogen 2.893 N/A THR 71.A OG1 THR 67.A O no hydrogen 2.913 N/A LEU 72.A N VAL 68.A O no hydrogen 2.950 N/A GLU 73.A N.A GLN 69.A O no hydrogen 2.920 N/A GLU 73.A N.B GLN 69.A O no hydrogen 2.911 N/A SER 74.A N GLY 70.A O no hydrogen 2.866 N/A SER 74.A OG THR 71.A O no hydrogen 2.666 N/A LEU 75.A N THR 71.A O no hydrogen 2.943 N/A GLY 76.A N GLU 73.A O.A no hydrogen 2.963 N/A GLY 76.A N GLU 73.A O.B no hydrogen 2.912 N/A ILE 77.A N LEU 72.A O no hydrogen 2.967 N/A SER 80.A N ALA 54.A O no hydrogen 3.040 N/A SER 82.A OG SER 232.A O no hydrogen 3.342 N/A ASN 83.A ND2 GLU 287.A OE2 no hydrogen 3.333 N/A SER 85.A N ASN 83.A OD1 no hydrogen 2.884 N/A SER 85.A OG LEU 229.A O no hydrogen 2.752 N/A SER 86.A N ASN 83.A O no hydrogen 2.893 N/A SER 86.A OG ASN 83.A O no hydrogen 2.679 N/A ILE 88.A N LEU 84.A O no hydrogen 2.883 N/A CYS 89.A N SER 85.A O no hydrogen 2.966 N/A CYS 89.A SG SER 85.A O no hydrogen 3.316 N/A LYS 91.A N ASN 133.A OD1 no hydrogen 2.680 N/A ASN 92.A ND2.A GLU 110.A OE1 no hydrogen 2.635 N/A ASN 92.A ND2.B GLU 158.A OE2 no hydrogen 3.504 N/A ASN 92.A ND2.B VAL 159.A O no hydrogen 3.447 N/A ILE 93.A N ASP 90.A OD2 no hydrogen 2.832 N/A SER 94.A N ASP 90.A O no hydrogen 2.906 N/A SER 94.A OG ASP 90.A O no hydrogen 2.767 N/A SER 94.A OG LYS 91.A O no hydrogen 3.021 N/A LYS 95.A N LYS 91.A O no hydrogen 2.933 N/A LYS 95.A NZ THR 105.A OG1 no hydrogen 2.816 N/A LYS 95.A NZ PRO 106.A O no hydrogen 2.743 N/A LYS 95.A NZ GLU 162.A OE2 no hydrogen 2.753 N/A LYS 96.A N ASN 92.A O.A no hydrogen 3.051 N/A LYS 96.A N ASN 92.A O.B no hydrogen 3.104 N/A LYS 96.A NZ GLU 110.A OE2 no hydrogen 2.886 N/A ILE 97.A N ILE 93.A O no hydrogen 3.180 N/A LEU 98.A N SER 94.A O no hydrogen 2.927 N/A ARG 99.A N LYS 95.A O no hydrogen 2.794 N/A ARG 99.A NH2 THR 105.A O no hydrogen 2.919 N/A ARG 99.A NH2 ASP 107.A OD1 no hydrogen 2.862 N/A TYR 100.A N LYS 96.A O no hydrogen 2.701 N/A GLU 101.A N ILE 97.A O no hydrogen 2.955 N/A GLY 102.A N ARG 99.A O no hydrogen 2.923 N/A ILE 103.A N LEU 98.A O no hydrogen 2.915 N/A THR 105.A OG1 VAL 246.A O no hydrogen 2.746 N/A TRP 108.A NE1 ASN 92.A OD1.A no hydrogen 3.038 N/A ILE 109.A N ILE 161.A O no hydrogen 2.823 N/A LEU 111.A N VAL 159.A O no hydrogen 3.057 N/A THR 112.A N GLU 114.A OE1 no hydrogen 2.929 N/A THR 112.A OG1 GLU 114.A OE1 no hydrogen 3.148 N/A LYS 113.A NZ PHE 153.A O no hydrogen 2.570 N/A ASP 119.A N ASN 117.A OD1 no hydrogen 3.093 N/A LEU 121.A N ASN 117.A O no hydrogen 3.043 N/A ASP 122.A N PHE 118.A O no hydrogen 2.955 N/A LYS 123.A N ASP 119.A O no hydrogen 3.352 N/A LEU 124.A N LEU 121.A O no hydrogen 2.757 N/A GLY 125.A N ASP 122.A O no hydrogen 3.176 N/A LEU 128.A N VAL 140.A O no hydrogen 2.920 N/A VAL 129.A N GLU 162.A O no hydrogen 2.790 N/A VAL 130.A N LYS 138.A O no hydrogen 2.826 N/A LYS 131.A N VAL 160.A O no hydrogen 2.777 N/A LYS 131.A NZ GLU 162.A OE1 no hydrogen 2.592 N/A ASN 133.A N GLU 158.A O no hydrogen 2.738 N/A ASN 133.A ND2 ASP 90.A OD2 no hydrogen 3.228 N/A ASN 133.A ND2 GLU 158.A OE2 no hydrogen 3.468 N/A LYS 138.A N VAL 130.A O no hydrogen 3.235 N/A VAL 140.A N LEU 128.A O no hydrogen 2.817 N/A TYR 141.A N GLU 145.A OE2 no hydrogen 2.790 N/A GLU 145.A N ASP 142.A OD1 no hydrogen 2.923 N/A LEU 146.A N ASP 142.A O no hydrogen 2.918 N/A ILE 147.A N LYS 143.A O no hydrogen 2.926 N/A SER 148.A N ASP 144.A O no hydrogen 2.974 N/A GLU 150.A N ILE 147.A O no hydrogen 3.043 N/A THR 151.A N SER 148.A O no hydrogen 3.131 N/A PHE 153.A N LEU 149.A O no hydrogen 2.857 N/A ASP 156.A N.A VAL 152.A O no hydrogen 2.929 N/A ASP 156.A N.B VAL 152.A O no hydrogen 2.942 N/A SER 157.A N ASP 156.A OD1.A no hydrogen 2.440 N/A GLU 158.A N ASP 156.A OD1.A no hydrogen 3.068 N/A VAL 159.A N LEU 111.A O no hydrogen 2.927 N/A VAL 160.A N LYS 131.A O no hydrogen 2.806 N/A ILE 161.A N ILE 109.A O no hydrogen 2.858 N/A GLU 162.A N VAL 129.A O no hydrogen 2.893 N/A LYS 163.A N ASP 107.A O no hydrogen 2.923 N/A TYR 164.A N PRO 127.A O no hydrogen 3.365 N/A GLU 168.A N VAL 239.A O no hydrogen 2.820 N/A THR 171.A N.A ILE 183.A O no hydrogen 2.901 N/A THR 171.A N.B ILE 183.A O no hydrogen 2.886 N/A THR 171.A OG1.A VAL 237.A O no hydrogen 3.401 N/A THR 171.A OG1.A ASP 238.A OD1 no hydrogen 2.851 N/A CYS 172.A N VAL 237.A O no hydrogen 2.746 N/A CYS 172.A SG VAL 237.A O no hydrogen 3.871 N/A ILE 174.A N ALA 235.A O no hydrogen 2.842 N/A PHE 175.A N LYS 178.A O no hydrogen 2.951 N/A ASP 176.A N VAL 233.A O no hydrogen 2.700 N/A LYS 178.A N PHE 175.A O no hydrogen 3.007 N/A LYS 178.A NZ ASP 176.A O no hydrogen 3.537 N/A GLN 179.A N GLN 179.A OE1 no hydrogen 2.752 N/A GLN 179.A NE2 ASN 219.A O no hydrogen 2.917 N/A LEU 180.A N SER 173.A O no hydrogen 3.009 N/A ILE 183.A N THR 171.A O.A no hydrogen 3.142 N/A ILE 183.A N THR 171.A O.B no hydrogen 3.122 N/A SER 184.A N GLU 206.A O no hydrogen 2.823 N/A ILE 185.A N GLU 169.A O no hydrogen 2.828 N/A ARG 186.A N ILE 204.A O no hydrogen 3.075 N/A ARG 186.A NH1 GLU 206.A OE2 no hydrogen 3.118 N/A HIS 187.A ND1 SER 202.A O no hydrogen 2.716 N/A ALA 188.A N SER 202.A OG no hydrogen 2.738 N/A GLU 190.A N LYS 197.A O no hydrogen 2.820 N/A PHE 192.A N ASN 195.A O no hydrogen 2.846 N/A ASN 195.A N PHE 192.A O no hydrogen 2.898 N/A LYS 197.A N GLU 190.A O no hydrogen 2.727 N/A LYS 197.A NZ GLU 190.A OE2 no hydrogen 3.154 N/A ASP 199.A N ALA 188.A O no hydrogen 2.911 N/A ALA 201.A N ASP 199.A OD2 no hydrogen 2.769 N/A SER 202.A N ASP 199.A O no hydrogen 3.116 N/A SER 202.A OG ASP 199.A O no hydrogen 3.122 N/A ILE 204.A N ARG 186.A O no hydrogen 2.675 N/A GLU 206.A N SER 184.A O no hydrogen 3.021 N/A ILE 208.A N ILE 182.A O no hydrogen 3.093 N/A LYS 215.A N PRO 211.A O no hydrogen 2.879 N/A GLU 216.A N ALA 212.A O no hydrogen 2.975 N/A ARG 217.A N.A GLU 213.A O no hydrogen 3.253 N/A ARG 217.A N.B GLU 213.A O no hydrogen 3.254 N/A VAL 218.A N LEU 214.A O no hydrogen 2.804 N/A ASN 219.A N LYS 215.A O no hydrogen 2.872 N/A LYS 220.A N GLU 216.A O no hydrogen 3.016 N/A ALA 221.A N ARG 217.A O.A no hydrogen 3.084 N/A ALA 221.A N ARG 217.A O.B no hydrogen 3.045 N/A SER 222.A N VAL 218.A O no hydrogen 2.971 N/A SER 222.A OG VAL 218.A O no hydrogen 3.552 N/A SER 222.A OG ASN 219.A O no hydrogen 3.417 N/A LEU 223.A N ASN 219.A O no hydrogen 3.345 N/A ALA 224.A N LYS 220.A O no hydrogen 3.114 N/A CYS 225.A N ALA 221.A O no hydrogen 2.897 N/A CYS 225.A SG ALA 221.A O no hydrogen 3.280 N/A TYR 226.A N SER 222.A O no hydrogen 3.053 N/A LYS 227.A N LEU 223.A O no hydrogen 2.944 N/A ALA 228.A N ALA 224.A O no hydrogen 2.861 N/A LEU 229.A N CYS 225.A O no hydrogen 2.978 N/A LYS 230.A N LYS 227.A O no hydrogen 3.237 N/A CYS 231.A N TYR 226.A O no hydrogen 3.116 N/A CYS 231.A SG SER 85.A OG no hydrogen 3.663 N/A SER 232.A N SER 82.A OG no hydrogen 2.886 N/A SER 232.A OG GLY 81.A O no hydrogen 3.111 N/A TYR 234.A N SER 232.A O no hydrogen 2.900 N/A ALA 235.A N ILE 174.A O no hydrogen 2.898 N/A ARG 236.A N ASN 249.A O no hydrogen 2.811 N/A ARG 236.A NE THR 171.A OG1.A no hydrogen 2.911 N/A ARG 236.A NE ASP 238.A OD1 no hydrogen 3.165 N/A ARG 236.A NH1 ASP 238.A OD1 no hydrogen 3.274 N/A ARG 236.A NH1 ASP 238.A OD2 no hydrogen 3.478 N/A VAL 237.A N CYS 172.A O no hydrogen 2.794 N/A ASP 238.A N GLU 247.A O no hydrogen 2.974 N/A LYS 240.A N ILE 243.A O no hydrogen 3.013 N/A ILE 243.A N LYS 240.A O no hydrogen 2.801 N/A VAL 246.A N GLU 104.A O no hydrogen 2.893 N/A ASN 249.A N ARG 236.A O no hydrogen 2.790 N/A ASN 249.A ND2 ARG 236.A O no hydrogen 3.014 N/A ASN 249.A ND2 ASP 238.A OD2 no hydrogen 3.163 N/A THR 254.A OG1 SER 257.A OG no hydrogen 2.739 N/A GLN 255.A N GLU 23.A OE1 no hydrogen 2.768 N/A GLN 255.A NE2 GLU 23.A OE1 no hydrogen 2.966 N/A SER 257.A N THR 254.A O no hydrogen 2.934 N/A SER 257.A OG THR 254.A OG1 no hydrogen 2.739 N/A LYS 261.A N SER 257.A O no hydrogen 3.148 N/A LYS 261.A NZ GLU 205.A OE1 no hydrogen 2.708 N/A SER 262.A N LEU 258.A O no hydrogen 2.949 N/A SER 262.A OG PRO 181.A O no hydrogen 2.631 N/A ALA 263.A N LEU 259.A O no hydrogen 2.866 N/A ASP 264.A N PRO 260.A O no hydrogen 2.888 N/A ALA 265.A N LYS 261.A O no hydrogen 3.075 N/A ALA 266.A N ALA 263.A O no hydrogen 2.898 N/A GLY 267.A N ASP 264.A O no hydrogen 2.776 N/A ILE 268.A N ALA 263.A O no hydrogen 2.778 N/A HIS 269.A ND1 SER 271.A OG no hydrogen 3.188 N/A SER 271.A OG HIS 269.A ND1 no hydrogen 3.188 N/A LYS 272.A N HIS 269.A O no hydrogen 3.034 N/A LEU 273.A N HIS 269.A O no hydrogen 2.956 N/A LEU 274.A N TYR 270.A O no hydrogen 3.079 N/A ASP 275.A N SER 271.A O no hydrogen 3.189 N/A ILE 277.A N LEU 274.A O no hydrogen 3.074 N/A GLU 278.A N ASP 275.A O no hydrogen 2.913 N/A SER 280.A N ILE 276.A O no hydrogen 2.924 N/A SER 280.A OG ILE 276.A O no hydrogen 2.584 N/A LEU 281.A N ILE 277.A O no hydrogen 2.957 N/A ARG 282.A N GLU 278.A O no hydrogen 3.311 N/A ARG 282.A NE GLU 286.A OE2 no hydrogen 2.855 N/A ARG 282.A NH1 ASP 176.A OD2 no hydrogen 2.926 N/A ARG 282.A NH2 ASP 176.A OD1 no hydrogen 3.009 N/A ARG 282.A NH2 ASP 176.A OD2 no hydrogen 3.470 N/A VAL 283.A N THR 279.A O no hydrogen 2.964 N/A ARG 284.A N SER 280.A O no hydrogen 2.806 N/A ARG 284.A NE GLU 287.A OE1 no hydrogen 2.719 N/A ARG 284.A NH1 TYR 79.A O no hydrogen 2.810 N/A ARG 284.A NH1 GLY 81.A O no hydrogen 2.783 N/A ARG 284.A NH2 GLY 81.A O no hydrogen 3.084 N/A ARG 284.A NH2 SER 232.A OG no hydrogen 3.158 N/A ARG 284.A NH2 GLU 287.A OE1 no hydrogen 3.524 N/A ARG 284.A NH2 GLU 287.A OE2 no hydrogen 2.768 N/A LYS 285.A N LEU 281.A O no hydrogen 3.052 N/A GLU 286.A N ARG 282.A O no hydrogen 3.030 N/A GLU 287.A N VAL 283.A O no hydrogen 3.054 N/A GLY 288.A N ARG 284.A O no hydrogen 3.171 N/A GLY 288.A N LYS 285.A O no hydrogen 3.023 N/A