Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3s19_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 5.A N THR 82.A OG1 no hydrogen 2.934 N/A TYR 5.A OH ASP 97.A OD1 no hydrogen 3.344 N/A TYR 5.A OH ASP 97.A OD2 no hydrogen 2.572 N/A ASP 6.A N SER 78.A OG no hydrogen 3.000 N/A SER 8.A N ASP 6.A OD1 no hydrogen 3.006 N/A SER 8.A OG ASP 6.A OD1 no hydrogen 2.687 N/A SER 8.A OG ASP 6.A OD2 no hydrogen 3.367 N/A LEU 9.A N ASP 6.A O no hydrogen 3.152 N/A LEU 10.A N PRO 7.A O no hydrogen 3.201 N/A GLN 11.A N.A SER 71.A OG no hydrogen 2.855 N/A GLN 11.A N.B SER 71.A OG no hydrogen 2.862 N/A VAL 13.A N LEU 66.A O no hydrogen 2.916 N/A ARG 15.A N ALA 64.A O no hydrogen 2.920 N/A ARG 15.A NE SER 63.A O no hydrogen 2.982 N/A ARG 15.A NE SER 63.A OG no hydrogen 2.926 N/A ARG 15.A NH1 ASP 34.A OD2 no hydrogen 2.907 N/A ARG 15.A NH2 ASP 34.A OD2 no hydrogen 3.001 N/A ARG 15.A NH2 SER 63.A OG no hydrogen 2.895 N/A LEU 17.A N PRO 14.A O no hydrogen 3.290 N/A ARG 19.A N ARG 15.A O no hydrogen 3.290 N/A ARG 19.A NE GLU 210.A OE1 no hydrogen 2.940 N/A ARG 19.A NE GLU 210.A OE2 no hydrogen 3.460 N/A ARG 19.A NH2 ALA 61.A O no hydrogen 2.872 N/A ARG 19.A NH2 GLU 210.A OE2 no hydrogen 2.861 N/A ASN 20.A N.A SER 16.A O no hydrogen 3.009 N/A ASN 20.A N.B SER 16.A O no hydrogen 3.019 N/A LEU 22.A N ARG 19.A O no hydrogen 3.005 N/A HIS 23.A N.A ASN 20.A O.A no hydrogen 2.925 N/A HIS 23.A N.A ASN 20.A O.B no hydrogen 3.084 N/A HIS 23.A N.B ASN 20.A O.A no hydrogen 2.900 N/A HIS 23.A N.B ASN 20.A O.B no hydrogen 3.058 N/A LEU 24.A N.B ARG 19.A O no hydrogen 3.268 N/A GLN 31.A N SER 243.A O no hydrogen 2.776 N/A CYS 33.A N PHE 241.A O no hydrogen 3.093 N/A CYS 33.A SG SER 247.A O no hydrogen 3.736 N/A ASP 34.A N ILE 59.A O no hydrogen 2.810 N/A ILE 35.A N ASN 239.A O no hydrogen 3.121 N/A TRP 36.A N VAL 57.A O no hydrogen 2.779 N/A THR 37.A N ASP 237.A O no hydrogen 3.091 N/A THR 37.A N ASP 237.A OD1 no hydrogen 3.213 N/A THR 37.A OG1 ASP 237.A OD1 no hydrogen 2.737 N/A LEU 38.A N GLY 55.A O no hydrogen 2.773 N/A TYR 39.A N GLY 235.A O no hydrogen 2.934 N/A TYR 39.A OH ASP 237.A OD2 no hydrogen 2.796 N/A SER 42.A OG GLN 51.A O no hydrogen 2.764 N/A TRP 43.A N GLN 51.A O no hydrogen 3.144 N/A LEU 44.A N THR 82.A O no hydrogen 2.965 N/A ASN 45.A N LEU 49.A O no hydrogen 2.914 N/A GLY 48.A N ASN 45.A O no hydrogen 3.115 N/A LEU 49.A N ASN 45.A OD1 no hydrogen 2.869 N/A GLN 51.A N TRP 43.A O no hydrogen 2.765 N/A GLN 51.A NE2 LEU 49.A O no hydrogen 3.171 N/A ALA 53.A N LEU 41.A O no hydrogen 2.998 N/A ILE 54.A N LYS 111.A O no hydrogen 2.941 N/A GLY 55.A N LEU 38.A O no hydrogen 2.947 N/A GLU 56.A N ASN 109.A O.A no hydrogen 2.889 N/A GLU 56.A N ASN 109.A O.B no hydrogen 2.951 N/A VAL 57.A N TRP 36.A O no hydrogen 2.914 N/A SER 58.A N THR 107.A O.A no hydrogen 2.976 N/A SER 58.A N THR 107.A O.B no hydrogen 2.845 N/A ILE 59.A N ASP 34.A O no hydrogen 2.882 N/A ALA 61.A N GLY 32.A O no hydrogen 2.971 N/A THR 62.A OG1 GLU 104.A OE1 no hydrogen 2.794 N/A THR 62.A OG1 GLU 104.A OE2 no hydrogen 3.389 N/A SER 63.A N PRO 60.A O no hydrogen 2.976 N/A SER 63.A OG PRO 60.A O no hydrogen 3.043 N/A SER 63.A OG ASN 65.A O no hydrogen 2.719 N/A ASN 65.A N ALA 102.A O no hydrogen 2.895 N/A LEU 66.A N VAL 13.A O no hydrogen 2.855 N/A GLU 68.A N GLN 11.A O.A no hydrogen 2.900 N/A GLU 68.A N GLN 11.A O.B no hydrogen 2.968 N/A LYS 70.A N GLU 68.A OE2 no hydrogen 2.882 N/A SER 71.A N GLU 68.A OE1 no hydrogen 2.805 N/A SER 71.A OG GLU 68.A O no hydrogen 2.726 N/A PHE 72.A N GLU 68.A O no hydrogen 3.031 N/A LYS 73.A N SER 69.A O.A no hydrogen 2.912 N/A LYS 73.A N SER 69.A O.B no hydrogen 2.901 N/A LYS 73.A NZ ASN 77.A OD1 no hydrogen 2.900 N/A LEU 74.A N LYS 70.A O no hydrogen 2.990 N/A TYR 75.A N SER 71.A O no hydrogen 2.904 N/A TYR 75.A OH ASP 97.A OD2 no hydrogen 2.581 N/A LEU 76.A N PHE 72.A O no hydrogen 2.892 N/A ASN 77.A N LYS 73.A O no hydrogen 2.842 N/A ASN 77.A ND2 ASN 80.A OD1 no hydrogen 3.283 N/A SER 78.A N LEU 74.A O no hydrogen 3.027 N/A SER 78.A N TYR 75.A O no hydrogen 3.075 N/A SER 78.A OG TYR 75.A O no hydrogen 2.613 N/A TYR 79.A N LEU 76.A O no hydrogen 2.936 N/A TYR 79.A OH TYR 75.A OH no hydrogen 2.732 N/A ASN 80.A N ASN 77.A O no hydrogen 2.919 N/A ASN 80.A ND2 SER 42.A O no hydrogen 2.985 N/A THR 82.A N TYR 79.A O no hydrogen 2.940 N/A THR 82.A OG1 GLN 4.A OE1 no hydrogen 3.545 N/A THR 82.A OG1 SER 78.A O no hydrogen 2.828 N/A ARG 83.A NH2 GLN 46.A O.A no hydrogen 3.439 N/A PHE 84.A N LEU 44.A O no hydrogen 2.860 N/A ALA 85.A N GLU 89.A OE1.A no hydrogen 3.204 N/A ALA 85.A N GLU 89.A OE1.B no hydrogen 3.384 N/A TRP 87.A NE1 GLN 51.A OE1 no hydrogen 2.934 N/A GLU 89.A N.A SER 86.A OG no hydrogen 3.076 N/A GLU 89.A N.B SER 86.A O no hydrogen 3.205 N/A GLU 89.A N.B SER 86.A OG no hydrogen 3.018 N/A VAL 90.A N SER 86.A O no hydrogen 3.406 N/A GLN 91.A N.A TRP 87.A O no hydrogen 2.959 N/A GLN 91.A N.B TRP 87.A O no hydrogen 2.958 N/A THR 92.A N.A ASP 88.A O.A no hydrogen 2.847 N/A THR 92.A N.A ASP 88.A O.B no hydrogen 2.969 N/A THR 92.A N.B ASP 88.A O.A no hydrogen 2.891 N/A THR 92.A N.B ASP 88.A O.B no hydrogen 3.010 N/A THR 92.A OG1.A ASP 88.A O.A no hydrogen 2.952 N/A THR 92.A OG1.A ASP 88.A O.B no hydrogen 2.874 N/A THR 92.A OG1.B ASP 88.A O.A no hydrogen 3.289 N/A THR 92.A OG1.B ASP 88.A O.B no hydrogen 3.231 N/A THR 92.A OG1.B GLU 89.A O.A no hydrogen 2.866 N/A THR 92.A OG1.B GLU 89.A O.B no hydrogen 2.892 N/A ARG 93.A N.A GLU 89.A O.A no hydrogen 2.873 N/A ARG 93.A N.A GLU 89.A O.B no hydrogen 2.962 N/A ARG 93.A N.B GLU 89.A O.A no hydrogen 2.920 N/A ARG 93.A N.B GLU 89.A O.B no hydrogen 3.011 N/A ARG 93.A NE.A GLU 89.A OE2.A no hydrogen 2.872 N/A ARG 93.A NH2.A GLU 89.A OE2.A no hydrogen 3.260 N/A LEU 94.A N VAL 90.A O no hydrogen 3.016 N/A VAL 95.A N GLN 91.A O.A no hydrogen 3.044 N/A VAL 95.A N GLN 91.A O.B no hydrogen 3.018 N/A HIS 96.A N THR 92.A O.A no hydrogen 2.999 N/A HIS 96.A N THR 92.A O.B no hydrogen 2.945 N/A HIS 96.A ND1 ASP 97.A OD1 no hydrogen 2.965 N/A ASP 97.A N ARG 93.A O.A no hydrogen 2.793 N/A ASP 97.A N ARG 93.A O.B no hydrogen 2.821 N/A LEU 98.A N LEU 94.A O no hydrogen 2.903 N/A SER 99.A N VAL 95.A O no hydrogen 2.957 N/A SER 99.A OG VAL 95.A O no hydrogen 2.650 N/A ALA 100.A N HIS 96.A O no hydrogen 3.022 N/A CYS 101.A N ASP 97.A O no hydrogen 3.082 N/A ALA 102.A N LEU 98.A O no hydrogen 2.908 N/A GLY 103.A N SER 99.A O no hydrogen 2.845 N/A VAL 106.A N.A SER 99.A OG no hydrogen 2.916 N/A VAL 106.A N.B SER 99.A OG no hydrogen 2.865 N/A THR 107.A N.A SER 58.A O no hydrogen 3.109 N/A THR 107.A N.B SER 58.A O no hydrogen 3.085 N/A ASN 109.A N.A GLU 56.A O no hydrogen 2.821 N/A ASN 109.A N.B GLU 56.A O no hydrogen 2.869 N/A ASN 109.A ND2.A GLU 56.A OE2 no hydrogen 3.508 N/A VAL 110.A N GLN 91.A OE1.A no hydrogen 3.046 N/A LYS 111.A N ILE 54.A O no hydrogen 2.905 N/A LYS 111.A NZ GLU 56.A OE2 no hydrogen 3.342 N/A SER 112.A OG ASN 114.A OD1.A no hydrogen 2.369 N/A GLU 115.A N SER 112.A O no hydrogen 3.081 N/A TYR 116.A N LEU 113.A O no hydrogen 2.962 N/A THR 117.A N ASN 114.A O.A no hydrogen 3.252 N/A THR 117.A N ASN 114.A O.B no hydrogen 3.241 N/A THR 117.A OG1 ASN 114.A O.A no hydrogen 3.543 N/A THR 117.A OG1 ASN 114.A O.B no hydrogen 3.531 N/A GLU 119.A N.A TYR 116.A O no hydrogen 3.012 N/A GLU 119.A N.B TYR 116.A O no hydrogen 3.006 N/A VAL 122.A N ARG 254.A O no hydrogen 2.878 N/A GLN 124.A N GLU 179.A OE1 no hydrogen 2.820 N/A GLU 126.A N.A VAL 157.A O no hydrogen 3.006 N/A GLU 126.A N.B VAL 157.A O no hydrogen 2.993 N/A CYS 127.A SG HIS 159.A O no hydrogen 3.965 N/A ILE 128.A N HIS 159.A O no hydrogen 2.868 N/A GLN 131.A NE2 ILE 128.A O no hydrogen 2.865 N/A GLN 131.A NE2 ARG 188.A O no hydrogen 3.036 N/A GLU 139.A N ASN 137.A OD1 no hydrogen 3.180 N/A ASP 141.A N SER 197.A OG no hydrogen 3.185 N/A ALA 143.A N ASP 141.A OD1 no hydrogen 3.075 N/A LEU 144.A N ASP 141.A O no hydrogen 3.158 N/A LEU 145.A N ASP 142.A O no hydrogen 3.056 N/A GLN 146.A N ALA 143.A O no hydrogen 2.934 N/A ALA 148.A N LEU 145.A O no hydrogen 2.936 N/A GLN 150.A NE2 GLY 147.A O no hydrogen 3.009 N/A GLY 151.A N LYS 186.A O no hydrogen 3.259 N/A VAL 154.A N GLY 184.A O no hydrogen 2.890 N/A SER 155.A OG HIS 183.A ND1 no hydrogen 2.730 N/A GLU 156.A N TYR 182.A O no hydrogen 3.036 N/A LEU 158.A N ILE 180.A O no hydrogen 2.826 N/A HIS 159.A N GLU 126.A O.A no hydrogen 2.839 N/A HIS 159.A N GLU 126.A O.B no hydrogen 2.933 N/A SER 160.A N VAL 178.A O no hydrogen 2.915 N/A SER 160.A OG ASP 129.A OD1 no hydrogen 2.613 N/A HIS 161.A N ASP 129.A OD2 no hydrogen 2.771 N/A HIS 161.A ND1 SER 177.A OG no hydrogen 2.838 N/A LEU 162.A N SER 160.A OG no hydrogen 3.004 N/A LYS 164.A NZ ASN 166.A OD1 no hydrogen 3.185 N/A LYS 164.A NZ ARG 199.A O no hydrogen 2.994 N/A SER 165.A N ASP 174.A O no hydrogen 3.116 N/A ASN 166.A N HIS 201.A O no hydrogen 2.768 N/A CYS 167.A N GLN 172.A O no hydrogen 2.774 N/A CYS 167.A SG THR 170.A OG1 no hydrogen 3.545 N/A THR 170.A OG1 CYS 167.A O no hydrogen 3.324 N/A ASP 174.A N SER 165.A O no hydrogen 2.757 N/A GLY 176.A N LEU 163.A O no hydrogen 2.857 N/A SER 177.A N ARG 229.A O no hydrogen 2.993 N/A SER 177.A OG HIS 161.A ND1 no hydrogen 2.838 N/A VAL 178.A N SER 160.A O no hydrogen 2.825 N/A GLU 179.A N TYR 227.A O no hydrogen 2.767 N/A ILE 180.A N LEU 158.A O no hydrogen 2.756 N/A ALA 181.A N THR 225.A O no hydrogen 2.933 N/A TYR 182.A N GLU 156.A O no hydrogen 2.990 N/A TYR 182.A OH GLU 156.A OE2 no hydrogen 2.545 N/A HIS 183.A N SER 223.A O no hydrogen 3.062 N/A HIS 183.A ND1 SER 155.A OG no hydrogen 2.730 N/A GLY 184.A N VAL 154.A O no hydrogen 2.964 N/A LYS 186.A N GLU 152.A O no hydrogen 3.037 N/A ARG 188.A NH1 GLU 126.A OE1.A no hydrogen 2.923 N/A ARG 188.A NH2 GLU 126.A OE1.A no hydrogen 3.241 N/A ARG 188.A NH2 GLU 126.A OE1.B no hydrogen 3.243 N/A ARG 188.A NH2 GLU 126.A OE2.A no hydrogen 2.928 N/A ARG 188.A NH2 GLU 156.A OE1 no hydrogen 2.633 N/A ALA 190.A N ASN 187.A OD1 no hydrogen 2.878 N/A LEU 191.A N ASN 187.A O no hydrogen 3.042 N/A LEU 192.A N ARG 188.A O no hydrogen 2.959 N/A ARG 193.A N GLU 189.A O no hydrogen 2.899 N/A ARG 193.A NE GLU 189.A OE2 no hydrogen 2.922 N/A ARG 193.A NH1 GLU 134.A O no hydrogen 2.851 N/A ARG 193.A NH2 GLU 134.A O no hydrogen 2.974 N/A ARG 193.A NH2 GLU 189.A OE2 no hydrogen 3.058 N/A TYR 194.A N ALA 190.A O no hydrogen 2.908 N/A TYR 194.A OH ASP 215.A OD2 no hydrogen 2.647 N/A LEU 195.A N LEU 191.A O no hydrogen 2.915 N/A VAL 196.A N LEU 192.A O no hydrogen 2.875 N/A SER 197.A N ARG 193.A O no hydrogen 2.998 N/A SER 197.A N TYR 194.A O no hydrogen 3.060 N/A SER 197.A OG TYR 194.A O no hydrogen 2.727 N/A PHE 198.A N LEU 195.A O no hydrogen 3.167 N/A ARG 199.A N VAL 196.A O no hydrogen 3.009 N/A HIS 201.A N PHE 198.A O no hydrogen 2.765 N/A HIS 201.A NE2 GLU 203.A OE1.A no hydrogen 2.932 N/A ASN 202.A ND2 ASN 171.A OD1 no hydrogen 3.591 N/A GLU 203.A N.B ASN 166.A O no hydrogen 3.335 N/A GLU 206.A N GLU 206.A OE1 no hydrogen 2.626 N/A CYS 208.A N.A PHE 204.A O no hydrogen 2.855 N/A CYS 208.A N.B PHE 204.A O no hydrogen 2.854 N/A CYS 208.A SG.A TYR 230.A OH no hydrogen 3.430 N/A CYS 208.A SG.B GLU 203.A O.A no hydrogen 3.722 N/A CYS 208.A SG.B PHE 204.A O no hydrogen 3.476 N/A VAL 209.A N HIS 205.A O no hydrogen 3.094 N/A GLU 210.A N GLU 206.A O no hydrogen 3.088 N/A ARG 211.A N GLN 207.A O no hydrogen 2.903 N/A ARG 211.A NE GLU 203.A OE1.A no hydrogen 2.841 N/A ARG 211.A NH2 GLU 203.A OE1.A no hydrogen 3.550 N/A ARG 211.A NH2 GLU 203.A OE1.B no hydrogen 3.254 N/A ARG 211.A NH2 GLU 203.A OE2.A no hydrogen 3.073 N/A ILE 212.A N CYS 208.A O.A no hydrogen 2.871 N/A ILE 212.A N CYS 208.A O.B no hydrogen 2.861 N/A PHE 213.A N VAL 209.A O no hydrogen 2.939 N/A THR 214.A N GLU 210.A O no hydrogen 2.945 N/A THR 214.A OG1 GLU 210.A O no hydrogen 2.902 N/A THR 214.A OG1 ARG 211.A O no hydrogen 3.194 N/A ASP 215.A N ARG 211.A O no hydrogen 2.833 N/A ILE 216.A N ILE 212.A O no hydrogen 2.910 N/A ARG 217.A NE ASP 215.A OD1 no hydrogen 2.892 N/A ARG 217.A NH2 ASP 215.A OD1 no hydrogen 2.895 N/A TYR 218.A N ASP 215.A O no hydrogen 2.914 N/A TYR 218.A OH ASP 142.A OD2 no hydrogen 2.514 N/A CYS 219.A N ILE 216.A O no hydrogen 2.760 N/A GLN 222.A N HIS 183.A O no hydrogen 2.709 N/A SER 223.A N HIS 183.A O no hydrogen 3.480 N/A LEU 224.A N SER 244.A OG no hydrogen 2.919 N/A THR 225.A N ALA 181.A O no hydrogen 2.796 N/A THR 225.A OG1 SER 243.A OG no hydrogen 2.715 N/A THR 225.A OG1 GLN 246.A OE1 no hydrogen 2.754 N/A VAL 226.A N ARG 242.A O no hydrogen 2.823 N/A TYR 227.A N GLU 179.A O no hydrogen 2.950 N/A ALA 228.A N PRO 240.A O no hydrogen 3.061 N/A ARG 229.A N SER 177.A O no hydrogen 2.866 N/A ARG 229.A NE GLN 257.A OE1 no hydrogen 2.821 N/A ARG 229.A NH1 TYR 227.A OH no hydrogen 2.785 N/A ARG 229.A NH1 ASN 252.A OD1 no hydrogen 2.887 N/A ARG 229.A NH2 ASN 252.A OD1 no hydrogen 3.013 N/A ARG 229.A NH2 GLN 257.A OE1 no hydrogen 3.081 N/A TYR 230.A N ILE 238.A O no hydrogen 3.338 N/A THR 231.A N TRP 175.A O no hydrogen 2.851 N/A ARG 232.A NH2 GLN 257.A O no hydrogen 2.842 N/A LEU 233.A N.A LEU 236.A O.A no hydrogen 2.876 N/A LEU 233.A N.A LEU 236.A O.B no hydrogen 2.916 N/A LEU 233.A N.B LEU 236.A O.A no hydrogen 2.876 N/A LEU 233.A N.B LEU 236.A O.B no hydrogen 2.916 N/A LEU 236.A N.A LEU 233.A O.A no hydrogen 3.282 N/A LEU 236.A N.A LEU 233.A O.B no hydrogen 3.348 N/A LEU 236.A N.B LEU 233.A O.A no hydrogen 3.296 N/A LEU 236.A N.B LEU 233.A O.B no hydrogen 3.362 N/A ASP 237.A N THR 37.A O no hydrogen 3.008 N/A ASN 239.A N ILE 35.A O no hydrogen 2.773 N/A ASN 239.A ND2 ILE 35.A O no hydrogen 2.961 N/A ASN 239.A ND2 ASP 237.A OD1 no hydrogen 2.957 N/A PHE 241.A N CYS 33.A O no hydrogen 2.851 N/A ARG 242.A N VAL 226.A O no hydrogen 2.884 N/A ARG 242.A NE GLU 210.A OE2 no hydrogen 2.823 N/A ARG 242.A NH1 CYS 33.A O no hydrogen 3.080 N/A ARG 242.A NH1 ASP 34.A OD1 no hydrogen 2.914 N/A ARG 242.A NH1 PHE 241.A O no hydrogen 2.961 N/A ARG 242.A NH2 ASP 34.A OD1 no hydrogen 2.848 N/A ARG 242.A NH2 GLU 210.A OE2 no hydrogen 3.081 N/A SER 243.A N GLN 31.A O no hydrogen 2.832 N/A SER 243.A OG LEU 224.A O no hydrogen 3.411 N/A SER 243.A OG THR 225.A OG1 no hydrogen 2.715 N/A SER 244.A N LEU 224.A O no hydrogen 2.839 N/A SER 244.A OG LEU 224.A O no hydrogen 3.302 N/A HIS 245.A N.B SER 243.A OG no hydrogen 3.138 N/A GLN 246.A N SER 243.A OG no hydrogen 2.811 N/A ASN 252.A ND2 THR 37.A OG1 no hydrogen 3.124 N/A ASN 252.A ND2 GLU 56.A OE1 no hydrogen 2.910 N/A GLN 253.A N HIS 251.A ND1.A no hydrogen 3.010 N/A ARG 256.A NH2 SER 177.A OG no hydrogen 2.995 N/A GLN 257.A NE2 TYR 230.A O no hydrogen 2.904 N/A GLN 257.A NE2 ASN 239.A OD1 no hydrogen 2.832 N/A