Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3sx0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N TYR 17.A O no hydrogen 2.896 N/A LEU 6.A N ALA 15.A O no hydrogen 2.856 N/A LYS 7.A N ASN 71.A OD1 no hydrogen 2.921 N/A LYS 7.A NZ ASP 75.A OD1 no hydrogen 2.825 N/A SER 8.A OG TRP 200.A O no hydrogen 2.685 N/A VAL 10.A N SER 8.A OG no hydrogen 3.013 N/A GLY 11.A N SER 8.A O no hydrogen 3.302 N/A ALA 12.A N SER 8.A OG no hydrogen 3.265 N/A ALA 15.A N LEU 6.A O no hydrogen 2.871 N/A TYR 17.A N LEU 4.A O no hydrogen 2.796 N/A TYR 17.A OH GLU 33.A OE2 no hydrogen 2.687 N/A TRP 19.A N LEU 2.A O no hydrogen 3.371 N/A TYR 24.A N HIS 28.A O no hydrogen 2.822 N/A TYR 24.A OH GLU 33.A OE1 no hydrogen 2.860 N/A ASP 25.A N HIS 28.A O no hydrogen 3.149 N/A HIS 27.A N ASP 25.A OD1 no hydrogen 2.710 N/A HIS 28.A N ASP 25.A OD1 no hydrogen 2.610 N/A ALA 30.A N PRO 22.A O no hydrogen 2.839 N/A HIS 32.A N ASP 29.A OD2 no hydrogen 2.931 N/A HIS 32.A ND1.A ASP 29.A OD2 no hydrogen 2.765 N/A GLU 33.A N ASP 29.A O no hydrogen 3.089 N/A ILE 34.A N ALA 30.A O no hydrogen 2.872 N/A ILE 35.A N ALA 31.A O no hydrogen 3.242 N/A GLU 36.A N HIS 32.A O no hydrogen 2.920 N/A THR 37.A N GLU 33.A O no hydrogen 2.812 N/A THR 37.A OG1 GLU 33.A O no hydrogen 2.698 N/A THR 37.A OG1 HIS 101.A NE2 no hydrogen 3.027 N/A THR 37.A OG1 TYR 201.A OH no hydrogen 3.330 N/A ILE 38.A N ILE 34.A O no hydrogen 3.025 N/A ARG 39.A N ILE 35.A O no hydrogen 3.071 N/A TRP 40.A N GLU 36.A O no hydrogen 2.843 N/A VAL 41.A N THR 37.A O no hydrogen 2.955 N/A CYS 42.A N ILE 38.A O no hydrogen 2.942 N/A CYS 42.A SG ILE 38.A O no hydrogen 3.374 N/A GLU 43.A N ARG 39.A O no hydrogen 3.148 N/A GLU 44.A N TRP 40.A O no hydrogen 3.011 N/A ILE 45.A N VAL 41.A O no hydrogen 2.984 N/A LYS 49.A N ILE 45.A O no hydrogen 3.001 N/A LYS 49.A NZ GLU 43.A OE2 no hydrogen 2.844 N/A LEU 50.A N PRO 46.A O no hydrogen 2.753 N/A ALA 51.A N ASP 47.A O no hydrogen 2.905 N/A MET 52.A N LEU 48.A O no hydrogen 2.877 N/A GLU 53.A N LYS 49.A O no hydrogen 2.837 N/A GLU 53.A N LEU 50.A O no hydrogen 3.168 N/A ASP 56.A N SER 62.A OG no hydrogen 3.281 N/A LYS 58.A N ASP 56.A OD1 no hydrogen 2.927 N/A SER 59.A N ASP 56.A O no hydrogen 3.242 N/A SER 62.A N SER 59.A OG no hydrogen 3.238 N/A SER 62.A OG ASP 54.A O no hydrogen 2.926 N/A MET 63.A N SER 59.A O no hydrogen 3.138 N/A GLN 64.A N PHE 60.A O no hydrogen 2.733 N/A ARG 65.A N GLU 61.A O no hydrogen 2.879 N/A LEU 66.A N SER 62.A O no hydrogen 3.235 N/A CYS 67.A N MET 63.A O no hydrogen 2.916 N/A CYS 67.A SG MET 63.A O no hydrogen 3.444 N/A ASP 68.A N GLN 64.A O no hydrogen 2.850 N/A LYS 69.A N ARG 65.A O no hydrogen 3.037 N/A TYR 70.A N LEU 66.A O no hydrogen 3.060 N/A TYR 70.A OH LYS 7.A O no hydrogen 2.763 N/A ASN 71.A N CYS 67.A O no hydrogen 2.781 N/A ASN 71.A ND2 ARG 5.A O no hydrogen 2.885 N/A ARG 72.A N ASP 68.A O no hydrogen 2.788 N/A ARG 72.A NH2 ASP 68.A OD2.B no hydrogen 2.617 N/A ALA 73.A N LYS 69.A O no hydrogen 3.153 N/A ILE 74.A N TYR 70.A O no hydrogen 2.887 N/A ASP 75.A N ASN 71.A O no hydrogen 3.055 N/A SER 76.A N ARG 72.A O no hydrogen 3.134 N/A SER 76.A OG ALA 73.A O no hydrogen 2.722 N/A ILE 77.A N ALA 73.A O no hydrogen 3.010 N/A HIS 78.A N ILE 74.A O no hydrogen 2.965 N/A HIS 78.A NE2 PRO 9.A O no hydrogen 2.864 N/A GLN 79.A N ASP 75.A O no hydrogen 3.129 N/A LEU 80.A N SER 76.A O no hydrogen 2.940 N/A TRP 81.A N ILE 77.A O no hydrogen 2.989 N/A LYS 82.A N GLN 79.A O no hydrogen 3.065 N/A GLY 83.A N GLN 79.A O no hydrogen 3.232 N/A GLY 83.A N LEU 80.A O no hydrogen 3.068 N/A THR 92.A OG1 ARG 93.A O no hydrogen 3.499 N/A ARG 93.A NH1 ALA 167.A O no hydrogen 3.255 N/A ARG 93.A NH1 THR 169.A O no hydrogen 2.637 N/A ARG 93.A NH2 THR 169.A O no hydrogen 3.211 N/A LEU 98.A N SER 95.A OG no hydrogen 3.174 N/A LEU 99.A N SER 95.A O no hydrogen 2.860 N/A ARG 100.A N THR 96.A O no hydrogen 3.011 N/A ARG 100.A NH2.A ASP 134.A OD1 no hydrogen 2.314 N/A ARG 100.A NH2.B ASP 134.A OD1 no hydrogen 3.358 N/A HIS 101.A N GLY 97.A O no hydrogen 3.341 N/A HIS 101.A NE2 THR 37.A OG1 no hydrogen 3.027 N/A ILE 102.A N LEU 98.A O no hydrogen 2.826 N/A LEU 103.A N LEU 99.A O no hydrogen 2.911 N/A GLN 104.A N ARG 100.A O no hydrogen 2.992 N/A GLN 105.A N HIS 101.A O no hydrogen 2.901 N/A GLN 105.A NE2 TYR 17.A OH no hydrogen 3.510 N/A GLN 105.A NE2 GLU 33.A OE2 no hydrogen 3.069 N/A GLN 105.A NE2 THR 37.A OG1 no hydrogen 2.950 N/A VAL 106.A N ILE 102.A O no hydrogen 2.792 N/A TYR 107.A N LEU 103.A O no hydrogen 2.853 N/A TYR 107.A OH GLU 130.A OE2 no hydrogen 2.695 N/A ASN 108.A N GLN 104.A O no hydrogen 2.953 N/A ASN 108.A ND2 GLN 104.A OE1 no hydrogen 2.967 N/A HIS 109.A N GLN 105.A O no hydrogen 3.010 N/A HIS 109.A NE2 GLU 33.A OE2 no hydrogen 2.555 N/A SER 110.A N VAL 106.A O no hydrogen 2.959 N/A SER 110.A N TYR 107.A O no hydrogen 3.037 N/A SER 110.A OG VAL 106.A O no hydrogen 2.755 N/A VAL 111.A N TYR 107.A O no hydrogen 2.705 N/A ASP 113.A N TYR 186.A OH no hydrogen 3.284 N/A LYS 116.A N ASP 113.A O no hydrogen 3.005 N/A LEU 117.A N PRO 114.A O no hydrogen 3.025 N/A ASN 118.A N GLU 115.A O no hydrogen 2.914 N/A ASN 118.A ND2 GLU 115.A OE2 no hydrogen 3.332 N/A ASN 119.A N LYS 116.A O no hydrogen 3.219 N/A SER 124.A OG GLU 121.A O no hydrogen 2.667 N/A SER 124.A OG GLU 126.A OE1 no hydrogen 3.323 N/A GLU 126.A N SER 124.A OG no hydrogen 2.972 N/A VAL 127.A N SER 124.A O no hydrogen 3.214 N/A TYR 128.A OH GLU 130.A OE2 no hydrogen 2.652 N/A LEU 135.A N SER 132.A OG no hydrogen 3.102 N/A VAL 136.A N SER 132.A O no hydrogen 3.220 N/A ALA 137.A N PHE 133.A O no hydrogen 2.871 N/A GLN 138.A N ASP 134.A O no hydrogen 2.951 N/A GLN 138.A NE2 GLU 142.A OE2 no hydrogen 3.010 N/A GLN 138.A NE2 SER 289.A O no hydrogen 2.767 N/A MET 139.A N LEU 135.A O no hydrogen 2.906 N/A ILE 140.A N VAL 136.A O no hydrogen 2.934 N/A ASP 141.A N ALA 137.A O no hydrogen 2.999 N/A GLU 142.A N GLN 138.A O no hydrogen 2.903 N/A GLU 142.A N MET 139.A O no hydrogen 3.218 N/A ILE 143.A N MET 139.A O no hydrogen 2.930 N/A LYS 144.A N ILE 140.A O no hydrogen 3.480 N/A THR 146.A N ASP 149.A OD2 no hydrogen 2.963 N/A ASP 148.A N THR 146.A OG1 no hydrogen 3.162 N/A ASP 149.A N THR 146.A O no hydrogen 3.036 N/A LEU 150.A N SER 228.A OG no hydrogen 3.089 N/A PHE 151.A N HIS 173.A O no hydrogen 3.129 N/A VAL 152.A N VAL 229.A O no hydrogen 3.018 N/A ASP 153.A N TYR 175.A O no hydrogen 2.903 N/A LEU 154.A N PHE 231.A O no hydrogen 2.891 N/A GLY 155.A N VAL 177.A O no hydrogen 2.783 N/A SER 156.A N VAL 177.A O no hydrogen 2.844 N/A GLY 157.A N GLU 178.A OE1 no hydrogen 2.897 N/A GLY 159.A N SER 156.A O no hydrogen 2.997 N/A GLN 160.A N GLN 160.A OE1 no hydrogen 2.782 N/A LEU 163.A N GLY 159.A O no hydrogen 3.179 N/A GLN 164.A N GLN 160.A O no hydrogen 3.146 N/A GLN 164.A NE2 PHE 133.A O no hydrogen 3.188 N/A VAL 165.A N VAL 161.A O no hydrogen 3.032 N/A ALA 166.A N VAL 162.A O no hydrogen 2.813 N/A ALA 167.A N LEU 163.A O no hydrogen 2.958 N/A ALA 168.A N GLN 164.A O no hydrogen 3.024 N/A ALA 168.A N VAL 165.A O no hydrogen 3.155 N/A THR 169.A N VAL 165.A O no hydrogen 2.907 N/A THR 169.A OG1 VAL 165.A O no hydrogen 3.319 N/A THR 169.A OG1 HIS 174.A NE2 no hydrogen 2.956 N/A CYS 171.A N THR 169.A OG1 no hydrogen 3.343 N/A CYS 171.A SG THR 169.A OG1 no hydrogen 3.590 N/A LYS 172.A N ASP 149.A O no hydrogen 3.105 N/A HIS 173.A NE2 THR 209.A OG1 no hydrogen 2.845 N/A HIS 174.A N GLU 207.A O no hydrogen 2.978 N/A HIS 174.A ND1 GLU 207.A O no hydrogen 3.050 N/A HIS 174.A NE2 THR 169.A OG1 no hydrogen 2.956 N/A TYR 175.A N PHE 151.A O no hydrogen 2.764 N/A GLY 176.A N THR 209.A O no hydrogen 3.084 N/A VAL 177.A N ASP 153.A O no hydrogen 3.368 N/A GLU 178.A N GLU 211.A O no hydrogen 3.014 N/A LYS 179.A NZ GLU 126.A OE2 no hydrogen 2.642 N/A ALA 180.A N GLU 178.A OE2 no hydrogen 2.788 N/A ALA 184.A N ALA 180.A O no hydrogen 3.130 N/A LYS 185.A N ASP 181.A O no hydrogen 2.861 N/A TYR 186.A N ILE 182.A O no hydrogen 3.221 N/A TYR 186.A OH ASP 113.A O no hydrogen 3.042 N/A ALA 187.A N PRO 183.A O no hydrogen 2.831 N/A GLU 188.A N ALA 184.A O no hydrogen 3.215 N/A GLU 188.A N LYS 185.A O no hydrogen 3.228 N/A MET 190.A N TYR 186.A O no hydrogen 2.873 N/A ASP 191.A N ALA 187.A O no hydrogen 2.951 N/A ARG 192.A N GLU 188.A O no hydrogen 3.360 N/A GLU 193.A N THR 189.A O no hydrogen 2.885 N/A PHE 194.A N MET 190.A O no hydrogen 2.803 N/A ARG 195.A N ASP 191.A O no hydrogen 3.077 N/A ARG 195.A NE ASP 191.A OD1 no hydrogen 2.784 N/A ARG 195.A NH2 ASP 191.A OD1 no hydrogen 3.386 N/A ARG 195.A NH2 TYR 208.A O no hydrogen 3.129 N/A LYS 196.A N ARG 192.A O no hydrogen 3.003 N/A LYS 196.A NZ GLU 193.A OE1 no hydrogen 2.824 N/A LYS 196.A NZ GLU 193.A OE2 no hydrogen 3.448 N/A TRP 197.A N GLU 193.A O no hydrogen 2.808 N/A MET 198.A N PHE 194.A O no hydrogen 2.883 N/A LYS 199.A N ARG 195.A O no hydrogen 3.104 N/A TRP 200.A N LYS 196.A O no hydrogen 2.947 N/A TYR 201.A N TRP 197.A O no hydrogen 2.943 N/A TYR 201.A OH THR 37.A OG1 no hydrogen 3.330 N/A TYR 201.A OH GLN 105.A OE1 no hydrogen 2.668 N/A GLY 202.A N LYS 199.A O no hydrogen 2.990 N/A LYS 203.A N MET 198.A O no hydrogen 2.918 N/A LYS 203.A NZ THR 92.A OG1 no hydrogen 2.847 N/A LYS 204.A N THR 92.A O no hydrogen 3.021 N/A HIS 205.A ND1 ALA 206.A O no hydrogen 2.636 N/A ALA 206.A N ALA 166.A O no hydrogen 2.854 N/A TYR 208.A OH ASP 191.A OD1 no hydrogen 2.531 N/A THR 209.A N HIS 174.A O no hydrogen 2.927 N/A THR 209.A OG1 HIS 173.A NE2 no hydrogen 2.845 N/A GLU 211.A N GLY 176.A O no hydrogen 2.835 N/A ARG 212.A NH1 ASP 181.A OD1.B no hydrogen 2.643 N/A ARG 212.A NH2 ASP 181.A OD1.B no hydrogen 2.785 N/A GLY 213.A N GLU 178.A O no hydrogen 2.998 N/A LEU 216.A N ASP 214.A OD1 no hydrogen 2.841 N/A SER 217.A N ASP 214.A O no hydrogen 3.075 N/A SER 217.A OG ASP 214.A O no hydrogen 3.219 N/A TRP 220.A N SER 217.A O no hydrogen 3.028 N/A TRP 220.A N SER 217.A OG no hydrogen 3.425 N/A ARG 221.A N GLU 218.A O no hydrogen 3.169 N/A ARG 221.A NE GLU 218.A OE2 no hydrogen 3.027 N/A ARG 223.A NH1 GLU 211.A OE2 no hydrogen 3.145 N/A ARG 223.A NH2 GLU 211.A OE1 no hydrogen 3.062 N/A ARG 223.A NH2 GLU 219.A OE1 no hydrogen 3.437 N/A ILE 224.A N TRP 220.A O no hydrogen 3.021 N/A ALA 225.A N ARG 221.A O no hydrogen 3.124 N/A ASN 226.A N GLU 222.A O no hydrogen 3.007 N/A ASN 226.A N ARG 223.A O no hydrogen 3.223 N/A THR 227.A N ILE 224.A O no hydrogen 3.143 N/A THR 227.A OG1 ARG 223.A O no hydrogen 2.674 N/A SER 228.A N LEU 150.A O no hydrogen 3.269 N/A SER 228.A OG ASP 149.A OD1 no hydrogen 2.528 N/A SER 228.A OG LEU 150.A O no hydrogen 3.435 N/A VAL 229.A N LEU 150.A O no hydrogen 2.999 N/A ILE 230.A N ARG 257.A O no hydrogen 2.855 N/A PHE 231.A N VAL 152.A O no hydrogen 2.742 N/A VAL 232.A N VAL 259.A O no hydrogen 2.938 N/A ASN 234.A ND2 ASP 242.A OD1 no hydrogen 3.126 N/A ASN 234.A ND2 ASP 242.A OD2 no hydrogen 3.532 N/A ASN 234.A ND2 LYS 262.A O no hydrogen 3.009 N/A PHE 237.A N ASN 234.A O no hydrogen 3.137 N/A ASP 242.A N GLY 238.A O no hydrogen 3.081 N/A HIS 243.A N PRO 239.A O no hydrogen 3.005 N/A GLN 244.A N GLU 240.A O no hydrogen 3.097 N/A LEU 245.A N VAL 241.A O no hydrogen 2.930 N/A LYS 246.A N ASP 242.A O no hydrogen 2.774 N/A LYS 246.A NZ PHE 264.A O no hydrogen 3.387 N/A GLU 247.A N HIS 243.A O no hydrogen 3.035 N/A ARG 248.A N GLN 244.A O no hydrogen 3.163 N/A ARG 248.A NH1 GLN 244.A O no hydrogen 2.897 N/A ARG 248.A NH2 LEU 216.A O no hydrogen 2.923 N/A PHE 249.A N LEU 245.A O no hydrogen 2.842 N/A ALA 250.A N LYS 246.A O no hydrogen 3.104 N/A ASN 251.A N ARG 248.A O no hydrogen 3.292 N/A MET 252.A N PHE 249.A O no hydrogen 2.921 N/A LYS 253.A NZ ASN 226.A OD1.B no hydrogen 2.648 N/A GLY 255.A N ILE 309.A O no hydrogen 2.891 N/A GLY 256.A N LYS 253.A O no hydrogen 2.934 N/A ARG 257.A N SER 228.A O no hydrogen 2.839 N/A ARG 257.A NH2 ILE 143.A O no hydrogen 2.757 N/A ILE 258.A N HIS 307.A O no hydrogen 2.865 N/A VAL 259.A N ILE 230.A O no hydrogen 2.841 N/A SER 260.A N TYR 305.A O no hydrogen 2.998 N/A SER 260.A OG LYS 262.A O no hydrogen 2.647 N/A SER 261.A N ASN 234.A OD1 no hydrogen 3.232 N/A SER 261.A OG ASN 233.A OD1 no hydrogen 2.707 N/A SER 261.A OG ASN 234.A OD1 no hydrogen 3.450 N/A LYS 262.A N ASN 234.A OD1 no hydrogen 2.902 N/A PHE 264.A N HIS 307.A NE2 no hydrogen 3.005 N/A ASN 272.A N ASN 275.A OD1 no hydrogen 2.779 N/A ARG 274.A N ASN 272.A OD1 no hydrogen 2.769 N/A ASN 275.A N ASN 272.A OD1 no hydrogen 3.223 N/A ASN 275.A ND2 ARG 270.A O no hydrogen 2.968 N/A ASP 278.A N ASN 275.A O no hydrogen 2.953 N/A THR 281.A N ASP 278.A O no hydrogen 2.997 N/A THR 281.A OG1 ASP 278.A O no hydrogen 2.659 N/A ILE 282.A N ILE 279.A O no hydrogen 3.195 N/A ARG 284.A N THR 308.A O no hydrogen 2.903 N/A ARG 284.A NE ASP 310.A OD2 no hydrogen 3.267 N/A VAL 286.A N LEU 306.A O no hydrogen 2.895 N/A LEU 288.A N TYR 304.A O no hydrogen 2.854 N/A SER 296.A N LYS 300.A O no hydrogen 2.822 N/A GLY 299.A N SER 296.A O no hydrogen 3.119 N/A VAL 302.A N SER 294.A O no hydrogen 3.246 N/A TYR 305.A N SER 260.A O no hydrogen 2.816 N/A LEU 306.A N VAL 286.A O no hydrogen 2.769 N/A HIS 307.A N ILE 258.A O no hydrogen 2.728 N/A HIS 307.A ND1 ILE 258.A O no hydrogen 2.883 N/A THR 308.A N ARG 284.A O no hydrogen 2.844 N/A ILE 309.A N GLY 256.A O no hydrogen 2.795 N/A ASP 310.A N ILE 282.A O no hydrogen 2.691 N/A ARG 311.A N GLU 254.A OE1 no hydrogen 3.160 N/A ARG 311.A N GLU 254.A OE2 no hydrogen 3.338 N/A ARG 311.A NH1 MET 252.A O no hydrogen 3.020 N/A ARG 311.A NH2 ALA 250.A O no hydrogen 2.957 N/A ARG 311.A NH2 MET 252.A O no hydrogen 2.999 N/A THR 312.A N ASP 310.A OD1 no hydrogen 3.135 N/A THR 312.A OG1 ASP 310.A OD1 no hydrogen 2.391 N/A GLU 315.A N ARG 311.A O no hydrogen 3.008 N/A ASN 316.A N THR 312.A O no hydrogen 2.798 N/A TYR 317.A N ILE 313.A O no hydrogen 3.171 N/A PHE 318.A N LEU 314.A O no hydrogen 3.074 N/A SER 319.A N GLU 315.A O no hydrogen 2.955 N/A SER 319.A OG GLU 315.A O no hydrogen 2.998 N/A SER 320.A N ASN 316.A O no hydrogen 2.897 N/A SER 320.A OG TYR 317.A O no hydrogen 2.711 N/A LEU 321.A N TYR 317.A O no hydrogen 3.150 N/A LEU 321.A N PHE 318.A O no hydrogen 3.145 N/A LYS 322.A N SER 319.A O no hydrogen 2.914 N/A ASN 323.A N SER 320.A O no hydrogen 3.088 N/A