Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3t4n_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N SER 1.A O no hydrogen 2.930 N/A SER 6.A N GLN 2.A O no hydrogen 3.013 N/A ILE 7.A N GLU 3.A O no hydrogen 3.079 N/A GLU 8.A N LYS 4.A O no hydrogen 3.083 N/A GLN 9.A N VAL 5.A O no hydrogen 2.965 N/A GLN 10.A N SER 6.A O no hydrogen 2.936 N/A LEU 11.A N ILE 7.A O no hydrogen 2.767 N/A ALA 12.A N GLU 8.A O no hydrogen 2.911 N/A VAL 13.A N GLN 9.A O no hydrogen 2.923 N/A GLU 14.A N GLN 10.A O no hydrogen 3.067 N/A SER 15.A N LEU 11.A O no hydrogen 3.053 N/A ILE 16.A N ALA 12.A O no hydrogen 2.906 N/A ARG 17.A N VAL 13.A O no hydrogen 2.764 N/A ARG 17.A NE GLU 14.A OE1 no hydrogen 3.307 N/A ARG 17.A NH1 ILE 307.A O no hydrogen 2.599 N/A ARG 17.A NH1 LEU 308.A O no hydrogen 3.564 N/A ARG 17.A NH2 GLU 14.A OE1 no hydrogen 3.104 N/A ARG 17.A NH2 GLU 14.A OE2 no hydrogen 3.258 N/A LYS 18.A N GLU 14.A O no hydrogen 3.067 N/A PHE 19.A N SER 15.A O no hydrogen 3.030 N/A LEU 20.A N ILE 16.A O no hydrogen 2.914 N/A ASN 21.A N ARG 17.A O no hydrogen 2.845 N/A SER 22.A N PHE 19.A O no hydrogen 3.051 N/A SER 22.A OG LYS 18.A O no hydrogen 2.697 N/A LYS 23.A N PHE 19.A O no hydrogen 2.975 N/A THR 24.A N ASP 27.A OD2 no hydrogen 2.882 N/A SER 25.A N ARG 120.A O no hydrogen 3.336 N/A TYR 26.A N PRO 118.A O no hydrogen 2.941 N/A ASP 27.A N THR 24.A O no hydrogen 3.181 N/A ASP 27.A N THR 24.A OG1 no hydrogen 3.312 N/A VAL 28.A N SER 25.A O no hydrogen 3.070 N/A LEU 29.A N TYR 26.A O no hydrogen 3.126 N/A TYR 33.A OH VAL 152.A O no hydrogen 2.816 N/A LEU 38.A N PRO 60.A O no hydrogen 3.048 N/A THR 40.A N TRP 62.A O no hydrogen 2.878 N/A THR 40.A OG1 TRP 62.A O no hydrogen 3.504 N/A SER 41.A N ASP 39.A OD2 no hydrogen 2.866 N/A SER 41.A OG ASP 39.A OD2 no hydrogen 2.630 N/A LEU 42.A N ASP 39.A O no hydrogen 2.954 N/A VAL 44.A N LEU 98.A O no hydrogen 2.871 N/A SER 47.A N LEU 43.A O no hydrogen 2.873 N/A SER 47.A OG VAL 44.A O no hydrogen 2.734 N/A LEU 48.A N VAL 44.A O no hydrogen 2.884 N/A ASN 49.A N LYS 45.A O no hydrogen 3.330 N/A VAL 50.A N LYS 46.A O no hydrogen 2.970 N/A LEU 51.A N SER 47.A O no hydrogen 3.013 N/A LEU 52.A N LEU 48.A O no hydrogen 3.046 N/A GLN 53.A N ASN 49.A O no hydrogen 2.715 N/A ASN 54.A N VAL 50.A O no hydrogen 3.130 N/A ASN 54.A N LEU 51.A O no hydrogen 3.312 N/A ILE 56.A N LEU 51.A O no hydrogen 3.100 N/A SER 58.A OG LEU 73.A O no hydrogen 3.170 N/A ALA 59.A N LEU 73.A O no hydrogen 3.090 N/A LEU 61.A N GLY 71.A O no hydrogen 2.867 N/A TRP 62.A N LEU 38.A O no hydrogen 2.753 N/A ASP 63.A N ARG 68.A O no hydrogen 2.855 N/A SER 64.A OG ASP 39.A OD1 no hydrogen 3.201 N/A LYS 65.A N ASP 63.A OD1 no hydrogen 3.056 N/A ARG 68.A N ASP 63.A O no hydrogen 3.274 N/A ALA 70.A N LEU 61.A O no hydrogen 2.806 N/A LEU 73.A N ALA 59.A O no hydrogen 2.809 N/A THR 74.A N ASP 77.A OD2 no hydrogen 2.749 N/A THR 74.A OG1 ASP 77.A OD2 no hydrogen 3.489 N/A ASP 77.A N THR 74.A O no hydrogen 3.100 N/A ILE 79.A N THR 75.A O no hydrogen 2.868 N/A ASN 80.A N THR 76.A O no hydrogen 2.909 N/A ASN 80.A ND2 GLU 107.A OE2 no hydrogen 2.842 N/A VAL 81.A N ASP 77.A O no hydrogen 3.245 N/A ILE 82.A N PHE 78.A O no hydrogen 3.175 N/A GLN 83.A N ILE 79.A O no hydrogen 3.412 N/A GLN 83.A NE2 THR 206.A OG1 no hydrogen 2.985 N/A TYR 84.A N ASN 80.A O no hydrogen 3.356 N/A TYR 85.A N VAL 81.A O no hydrogen 2.896 N/A PHE 86.A N ILE 82.A O no hydrogen 2.805 N/A SER 87.A N GLN 83.A O no hydrogen 3.096 N/A ASN 88.A N TYR 85.A O no hydrogen 3.352 N/A ASN 88.A ND2 TYR 84.A O no hydrogen 2.879 N/A LYS 91.A N ASN 88.A O no hydrogen 3.020 N/A LYS 91.A NZ ASP 90.A OD2 no hydrogen 3.519 N/A PHE 92.A N PRO 89.A O no hydrogen 3.318 N/A LEU 94.A N LYS 91.A O no hydrogen 2.781 N/A VAL 95.A N PHE 92.A O no hydrogen 3.362 N/A LYS 97.A N LEU 94.A O no hydrogen 2.883 N/A LEU 98.A N VAL 95.A O no hydrogen 3.139 N/A LEU 100.A N LEU 42.A O no hydrogen 2.814 N/A ASP 101.A N THR 40.A O no hydrogen 2.872 N/A LEU 103.A N GLN 99.A O no hydrogen 2.777 N/A LYS 104.A N LEU 100.A O no hydrogen 3.007 N/A LYS 104.A NZ LEU 72.A O no hydrogen 2.973 N/A LYS 104.A NZ ASP 77.A OD1 no hydrogen 2.767 N/A LYS 104.A NZ ASP 77.A OD2 no hydrogen 3.381 N/A ASP 105.A N ASP 101.A O no hydrogen 3.068 N/A ILE 106.A N GLY 102.A O no hydrogen 2.937 N/A GLU 107.A N LEU 103.A O no hydrogen 3.077 N/A ARG 108.A N LYS 104.A O no hydrogen 2.977 N/A ALA 109.A N ASP 105.A O no hydrogen 2.804 N/A LEU 110.A N ILE 106.A O no hydrogen 2.992 N/A GLY 111.A N ARG 108.A O no hydrogen 2.995 N/A VAL 112.A N GLU 107.A O no hydrogen 2.818 N/A ILE 116.A N PRO 138.A O no hydrogen 3.040 N/A ARG 120.A N HIS 117.A O no hydrogen 2.957 N/A ARG 120.A NE GLU 124.A OE1 no hydrogen 2.784 N/A ARG 120.A NH2 GLU 124.A OE1 no hydrogen 3.168 N/A LEU 122.A N LYS 23.A O no hydrogen 2.795 N/A PHE 123.A N LEU 20.A O no hydrogen 3.032 N/A ALA 125.A N PRO 121.A O no hydrogen 3.291 N/A CYS 126.A N LEU 122.A O no hydrogen 3.057 N/A CYS 126.A SG LEU 122.A O no hydrogen 3.362 N/A LEU 127.A N PHE 123.A O no hydrogen 3.033 N/A LYS 128.A N GLU 124.A O no hydrogen 3.018 N/A MET 129.A N ALA 125.A O no hydrogen 3.112 N/A LEU 130.A N CYS 126.A O no hydrogen 3.002 N/A GLU 131.A N LEU 127.A O no hydrogen 2.878 N/A SER 132.A N LYS 128.A O no hydrogen 2.916 N/A SER 132.A OG LYS 128.A O no hydrogen 3.230 N/A SER 132.A OG MET 129.A O no hydrogen 3.034 N/A SER 132.A OG SER 134.A OG no hydrogen 2.575 N/A ARG 133.A N LEU 130.A O no hydrogen 3.219 N/A SER 134.A N MET 129.A O no hydrogen 3.208 N/A SER 134.A OG SER 132.A OG no hydrogen 2.575 N/A SER 134.A OG ARG 136.A O no hydrogen 3.103 N/A ILE 137.A N LEU 155.A O no hydrogen 2.720 N/A LEU 139.A N SER 153.A O no hydrogen 2.725 N/A ILE 140.A N ILE 116.A O no hydrogen 2.818 N/A ASP 141.A N ILE 150.A O no hydrogen 3.052 N/A GLN 142.A N ASP 141.A OD1 no hydrogen 2.698 N/A ASP 143.A N ARG 148.A O no hydrogen 2.920 N/A GLU 145.A N ASP 143.A OD2 no hydrogen 3.097 N/A THR 146.A N ASP 143.A OD2 no hydrogen 3.231 N/A HIS 147.A N ASP 143.A O no hydrogen 2.789 N/A ARG 148.A N THR 146.A OG1 no hydrogen 3.279 N/A ILE 150.A N ASP 141.A O no hydrogen 2.754 N/A VAL 152.A N LEU 139.A O no hydrogen 2.797 N/A LEU 155.A N ILE 137.A O no hydrogen 2.806 N/A GLN 157.A N GLY 135.A O no hydrogen 2.762 N/A TYR 158.A OH ILE 277.A O no hydrogen 2.853 N/A TYR 158.A OH ALA 280.A O no hydrogen 2.820 N/A ARG 159.A N THR 156.A OG1 no hydrogen 3.051 N/A ILE 160.A N THR 156.A O no hydrogen 3.134 N/A LEU 161.A N GLN 157.A O no hydrogen 2.948 N/A LYS 162.A N TYR 158.A O no hydrogen 2.850 N/A PHE 163.A N ARG 159.A O no hydrogen 2.906 N/A VAL 164.A N ILE 160.A O no hydrogen 2.856 N/A ALA 165.A N LEU 161.A O no hydrogen 2.940 N/A LEU 166.A N LYS 162.A O no hydrogen 2.854 N/A ASN 167.A N PHE 163.A O no hydrogen 3.240 N/A ASN 167.A N VAL 164.A O no hydrogen 3.302 N/A CYS 168.A N VAL 164.A O no hydrogen 2.881 N/A THR 171.A N CYS 168.A O no hydrogen 3.234 N/A THR 171.A OG1 CYS 168.A O no hydrogen 3.367 N/A HIS 172.A N ARG 169.A O no hydrogen 3.014 N/A PHE 173.A N GLU 170.A O no hydrogen 2.914 N/A LEU 174.A N THR 171.A O no hydrogen 3.070 N/A ILE 178.A N ASP 268.A O no hydrogen 2.804 N/A GLY 179.A N LYS 266.A O no hydrogen 3.098 N/A ASP 180.A N PRO 177.A O no hydrogen 2.910 N/A LEU 181.A N ILE 178.A O no hydrogen 2.946 N/A THR 185.A N VAL 297.A O no hydrogen 3.130 N/A THR 185.A OG1 VAL 297.A O no hydrogen 3.296 N/A CYS 192.A N PRO 214.A O no hydrogen 3.013 N/A CYS 192.A SG GLN 193.A O no hydrogen 3.846 N/A GLN 193.A N THR 196.A OG1 no hydrogen 3.129 N/A THR 196.A N GLN 193.A O no hydrogen 3.072 N/A THR 196.A OG1 GLN 193.A O no hydrogen 3.152 N/A VAL 198.A N LEU 245.A O no hydrogen 2.966 N/A ASP 200.A N PRO 197.A O no hydrogen 3.070 N/A VAL 201.A N PRO 197.A O no hydrogen 3.304 N/A ILE 202.A N VAL 198.A O no hydrogen 2.814 N/A GLN 203.A N ILE 199.A O no hydrogen 2.925 N/A MET 204.A N ASP 200.A O no hydrogen 3.049 N/A LEU 205.A N VAL 201.A O no hydrogen 3.111 N/A THR 206.A N ILE 202.A O no hydrogen 3.338 N/A THR 206.A OG1 GLN 203.A O no hydrogen 2.778 N/A GLN 207.A N GLN 203.A O no hydrogen 2.738 N/A GLY 208.A N MET 204.A O no hydrogen 2.808 N/A ARG 209.A N THR 206.A O no hydrogen 3.200 N/A VAL 210.A N LEU 205.A O no hydrogen 3.117 N/A VAL 213.A N TYR 226.A O no hydrogen 2.779 N/A ILE 215.A N ASN 224.A O no hydrogen 2.734 N/A ILE 216.A N CYS 192.A O no hydrogen 2.875 N/A ASP 217.A N TYR 221.A O no hydrogen 3.019 N/A ASN 219.A N ASP 217.A OD1 no hydrogen 2.854 N/A GLY 220.A N ASP 217.A O no hydrogen 2.941 N/A TYR 221.A N ASP 217.A OD1 no hydrogen 3.044 N/A LEU 222.A N GLY 292.A O no hydrogen 2.983 N/A ILE 223.A N ILE 215.A O no hydrogen 2.921 N/A ASN 224.A N ILE 215.A O no hydrogen 3.300 N/A VAL 225.A N ASN 224.A OD1 no hydrogen 2.671 N/A TYR 226.A N VAL 213.A O no hydrogen 2.834 N/A GLU 227.A N ASP 230.A OD2 no hydrogen 2.810 N/A ALA 228.A N SER 211.A O no hydrogen 2.790 N/A ASP 230.A N GLU 227.A O no hydrogen 2.831 N/A VAL 231.A N ALA 228.A O no hydrogen 3.015 N/A LEU 232.A N TYR 229.A O no hydrogen 3.057 N/A LEU 234.A N ASP 230.A O no hydrogen 3.240 N/A ILE 235.A N VAL 231.A O no hydrogen 3.094 N/A LYS 236.A N LEU 232.A O no hydrogen 3.073 N/A SER 244.A N ASN 241.A O no hydrogen 2.951 N/A SER 244.A OG ASN 241.A O no hydrogen 2.616 N/A LEU 245.A N ASP 242.A O no hydrogen 3.170 N/A SER 246.A N GLU 249.A OE1 no hydrogen 3.310 N/A SER 246.A OG GLU 249.A OE1 no hydrogen 3.428 N/A VAL 247.A N THR 196.A O no hydrogen 2.784 N/A GLY 248.A N MET 194.A O no hydrogen 3.035 N/A ALA 250.A N SER 246.A O no hydrogen 2.926 N/A LEU 251.A N VAL 247.A O no hydrogen 2.949 N/A MET 252.A N GLU 249.A O no hydrogen 3.026 N/A ARG 253.A N ALA 250.A O no hydrogen 3.133 N/A ARG 253.A NE ASP 242.A OD2 no hydrogen 2.782 N/A ARG 253.A NH2 ASP 242.A OD1 no hydrogen 3.108 N/A ARG 253.A NH2 ASP 242.A OD2 no hydrogen 3.369 N/A ARG 254.A N LEU 251.A O no hydrogen 2.944 N/A ARG 254.A NE ASP 230.A OD1 no hydrogen 2.967 N/A ARG 254.A NH1 ASN 224.A OD1 no hydrogen 2.804 N/A ARG 254.A NH2 VAL 225.A O no hydrogen 2.511 N/A ARG 254.A NH2 ASP 230.A OD2 no hydrogen 2.731 N/A PHE 258.A N SER 255.A O no hydrogen 3.059 N/A CYS 264.A N PHE 286.A O no hydrogen 2.965 N/A CYS 264.A SG THR 265.A O no hydrogen 3.703 N/A THR 265.A N ASP 268.A OD2 no hydrogen 2.999 N/A ASN 267.A N THR 265.A OG1 no hydrogen 3.258 N/A ASP 268.A N THR 265.A O no hydrogen 3.295 N/A LYS 269.A NZ ASN 267.A O no hydrogen 3.189 N/A SER 271.A N LEU 174.A O no hydrogen 3.093 N/A SER 271.A OG LEU 174.A O no hydrogen 3.270 N/A ILE 273.A N LYS 269.A O no hydrogen 3.064 N/A MET 274.A N LEU 270.A O no hydrogen 2.713 N/A ASP 275.A N SER 271.A O no hydrogen 2.965 N/A ASN 276.A N THR 272.A O no hydrogen 2.985 N/A ILE 277.A N ILE 273.A O no hydrogen 2.965 N/A ARG 278.A N MET 274.A O no hydrogen 2.956 N/A LYS 279.A N ASP 275.A O no hydrogen 3.021 N/A ALA 280.A N ASN 276.A O no hydrogen 2.891 N/A ARG 284.A NH1 GLU 227.A OE2 no hydrogen 3.137 N/A PHE 285.A N LEU 298.A O no hydrogen 2.790 N/A PHE 286.A N TYR 262.A O no hydrogen 2.898 N/A VAL 287.A N GLY 296.A O no hydrogen 2.768 N/A VAL 288.A N CYS 264.A O no hydrogen 2.913 N/A ASP 289.A N ARG 293.A O no hydrogen 2.955 N/A VAL 291.A N ASP 289.A OD1 no hydrogen 2.975 N/A GLY 292.A N ASP 289.A O no hydrogen 3.251 N/A ARG 293.A N ASP 289.A OD1 no hydrogen 2.835 N/A ARG 293.A NE ASP 289.A OD2 no hydrogen 2.828 N/A ARG 293.A NH2 ASP 289.A OD2 no hydrogen 3.052 N/A LEU 294.A N GLY 220.A O no hydrogen 3.058 N/A VAL 295.A N VAL 287.A O no hydrogen 2.884 N/A GLY 296.A N VAL 287.A O no hydrogen 3.164 N/A VAL 297.A N THR 185.A O no hydrogen 3.080 N/A LEU 298.A N PHE 285.A O no hydrogen 2.851 N/A THR 299.A N ASP 302.A OD2 no hydrogen 2.990 N/A THR 299.A OG1 SER 301.A OG no hydrogen 3.003 N/A THR 299.A OG1 ASP 302.A OD2 no hydrogen 3.063 N/A SER 301.A OG THR 299.A OG1 no hydrogen 3.003 N/A ILE 303.A N THR 299.A O no hydrogen 3.064 N/A LEU 304.A N LEU 300.A O no hydrogen 2.848 N/A LYS 305.A N SER 301.A O no hydrogen 2.948 N/A TYR 306.A N ASP 302.A O no hydrogen 3.264 N/A TYR 306.A OH GLN 9.A OE1 no hydrogen 2.780 N/A ILE 307.A N ILE 303.A O no hydrogen 3.109 N/A LEU 308.A N LEU 304.A O no hydrogen 2.890 N/A LEU 309.A N LYS 305.A O no hydrogen 2.735 N/A GLY 310.A N TYR 306.A O no hydrogen 2.801 N/A SER 311.A OG LEU 181.A O no hydrogen 2.949 N/A