Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3tbb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 7.A N ASP 149.A O no hydrogen 2.838 N/A GLY 11.A N ASP 50.A OD1 no hydrogen 3.009 N/A GLU 12.A N ASP 50.A OD1 no hydrogen 3.134 N/A LYS 14.A N THR 51.A O no hydrogen 2.739 N/A LYS 14.A NZ ASP 50.A OD2 no hydrogen 2.734 N/A ILE 16.A N HIS 53.A O no hydrogen 3.104 N/A LYS 17.A NZ TYR 19.A OH no hydrogen 3.000 N/A LEU 18.A N GLU 55.A O no hydrogen 3.004 N/A TYR 19.A N GLY 31.A O no hydrogen 2.719 N/A ALA 20.A N GLU 57.A O no hydrogen 3.036 N/A GLU 21.A N GLY 29.A O no hydrogen 2.918 N/A ARG 22.A NH2 ASP 61.A OD1 no hydrogen 3.451 N/A LEU 23.A N GLN 27.A O no hydrogen 2.756 N/A GLN 27.A N GLY 24.A O no hydrogen 3.372 N/A MET 28.A N ASN 136.A O no hydrogen 2.863 N/A GLY 29.A N GLU 21.A O no hydrogen 2.902 N/A TYR 30.A OH SER 65.A O no hydrogen 2.833 N/A GLY 31.A N TYR 19.A O no hydrogen 2.926 N/A LYS 34.A NZ GLU 57.A OE1 no hydrogen 3.328 N/A GLY 35.A N GLU 21.A OE1 no hydrogen 3.144 N/A GLY 35.A N GLU 21.A OE2 no hydrogen 2.450 N/A LYS 36.A N GLU 33.A O no hydrogen 2.854 N/A LYS 36.A NZ GLU 33.A OE2 no hydrogen 3.034 N/A ALA 37.A N GLU 21.A OE1 no hydrogen 3.345 N/A THR 38.A N TYR 30.A O no hydrogen 2.919 N/A THR 38.A OG1 PRO 40.A O no hydrogen 2.787 N/A GLY 41.A N TYR 139.A O no hydrogen 2.664 N/A ILE 44.A N PRO 141.A O no hydrogen 3.141 N/A LEU 46.A N ILE 143.A O no hydrogen 2.889 N/A ASN 47.A N ASP 50.A OD2 no hydrogen 2.892 N/A GLU 48.A N ARG 145.A O no hydrogen 2.970 N/A GLY 49.A N THR 99.A OG1 no hydrogen 2.772 N/A ASP 50.A N ASN 47.A O no hydrogen 2.838 N/A THR 51.A N GLU 12.A O no hydrogen 3.084 N/A LEU 52.A N TRP 97.A O no hydrogen 2.759 N/A HIS 53.A N LYS 14.A O no hydrogen 2.951 N/A HIS 53.A ND1 THR 96.A OG1 no hydrogen 2.895 N/A ILE 54.A N TYR 95.A O no hydrogen 2.701 N/A GLU 55.A N ILE 16.A O no hydrogen 2.987 N/A PHE 56.A N ARG 93.A O no hydrogen 2.737 N/A GLU 57.A N LEU 18.A O no hydrogen 3.053 N/A ASN 58.A N GLY 91.A O no hydrogen 3.084 N/A ASN 58.A ND2 VAL 62.A O no hydrogen 2.740 N/A ASN 58.A ND2 VAL 87.A O no hydrogen 3.007 N/A THR 59.A N ALA 20.A O no hydrogen 3.108 N/A THR 59.A OG1 ALA 20.A O no hydrogen 2.671 N/A MET 60.A N ASN 58.A OD1 no hydrogen 2.824 N/A VAL 64.A N VAL 87.A O no hydrogen 3.083 N/A SER 65.A N ASP 122.A OD1 no hydrogen 3.111 N/A SER 65.A OG GLY 79.A O no hydrogen 2.744 N/A LEU 66.A N TYR 95.A OH no hydrogen 3.276 N/A HIS 67.A N HIS 121.A O no hydrogen 2.922 N/A HIS 67.A ND1 ASP 78.A O no hydrogen 2.631 N/A HIS 69.A N HIS 119.A O no hydrogen 2.852 N/A ASP 72.A N ARG 98.A O no hydrogen 2.777 N/A SER 77.A N GLU 74.A O no hydrogen 2.742 N/A ASP 78.A N ILE 75.A O no hydrogen 3.024 N/A THR 80.A N SER 85.A OG no hydrogen 2.948 N/A THR 80.A OG1 ASP 78.A OD2 no hydrogen 3.472 N/A THR 80.A OG1 SER 83.A OG no hydrogen 3.044 N/A SER 83.A N THR 80.A OG1 no hydrogen 3.135 N/A SER 83.A OG ILE 75.A O no hydrogen 3.500 N/A SER 83.A OG THR 80.A O no hydrogen 3.367 N/A SER 83.A OG THR 80.A OG1 no hydrogen 3.044 N/A SER 83.A OG SER 85.A OG no hydrogen 2.213 N/A ARG 84.A N LYS 81.A O no hydrogen 2.877 N/A SER 85.A N THR 80.A O no hydrogen 2.878 N/A SER 85.A OG THR 80.A O no hydrogen 3.156 N/A SER 85.A OG SER 83.A OG no hydrogen 2.213 N/A VAL 87.A N VAL 64.A O no hydrogen 2.752 N/A GLY 91.A N GLU 88.A O no hydrogen 2.767 N/A ARG 93.A N PHE 56.A O no hydrogen 2.865 N/A THR 94.A OG1 GLU 55.A OE1 no hydrogen 2.869 N/A TYR 95.A N ILE 54.A O no hydrogen 2.911 N/A TYR 95.A OH SER 85.A O no hydrogen 2.624 N/A THR 96.A N SER 77.A OG no hydrogen 3.009 N/A THR 96.A OG1 HIS 53.A ND1 no hydrogen 2.895 N/A TRP 97.A N LEU 52.A O no hydrogen 2.839 N/A ARG 98.A N ASP 72.A O no hydrogen 2.690 N/A THR 99.A OG1 ASN 47.A O no hydrogen 3.493 N/A THR 99.A OG1 ASP 50.A O no hydrogen 2.850 N/A HIS 100.A N SER 114.A OG no hydrogen 2.978 N/A HIS 100.A ND1 ASP 72.A OD2 no hydrogen 2.594 N/A HIS 100.A NE2 ALA 112.A O no hydrogen 2.833 N/A GLY 103.A N ARG 111.A O no hydrogen 3.245 N/A ARG 104.A NH1 GLY 108.A O no hydrogen 2.762 N/A ARG 105.A N THR 109.A O no hydrogen 2.649 N/A ARG 105.A NH1 THR 109.A OG1 no hydrogen 3.111 N/A GLY 108.A N ARG 105.A O no hydrogen 2.891 N/A THR 109.A N ASP 107.A OD1 no hydrogen 2.817 N/A THR 109.A OG1 ASP 107.A OD1 no hydrogen 2.390 N/A THR 109.A OG1 ASP 107.A OD2 no hydrogen 3.397 N/A ARG 111.A N GLY 103.A O no hydrogen 2.765 N/A SER 114.A N HIS 100.A O no hydrogen 3.015 N/A SER 114.A OG HIS 100.A ND1 no hydrogen 3.271 N/A ALA 115.A N GLU 48.A OE2 no hydrogen 2.767 N/A GLY 116.A N VAL 144.A O no hydrogen 3.018 N/A TYR 117.A OH GLU 185.A OE2 no hydrogen 2.614 N/A TRP 118.A N VAL 142.A O no hydrogen 2.755 N/A TRP 118.A NE1 SER 114.A O no hydrogen 2.907 N/A HIS 119.A NE2 ALA 231.A O no hydrogen 2.886 N/A TYR 120.A N GLY 140.A O no hydrogen 2.965 N/A TYR 120.A OH PRO 42.A O no hydrogen 2.531 N/A HIS 121.A N HIS 67.A O no hydrogen 2.892 N/A HIS 121.A ND1 ASP 122.A O no hydrogen 2.864 N/A ASP 122.A N LEU 138.A O no hydrogen 3.150 N/A HIS 123.A N SER 65.A OG no hydrogen 2.757 N/A HIS 123.A ND1 HIS 123.A O no hydrogen 2.885 N/A HIS 123.A ND1 GLU 128.A O no hydrogen 2.965 N/A VAL 124.A N ASP 122.A OD1 no hydrogen 2.885 N/A VAL 125.A N ASP 122.A OD2 no hydrogen 2.717 N/A THR 127.A OG1 THR 131.A OG1 no hydrogen 3.189 N/A HIS 129.A N THR 127.A OG1 no hydrogen 3.088 N/A GLY 130.A N THR 127.A O no hydrogen 2.937 N/A THR 131.A N THR 127.A OG1 no hydrogen 3.239 N/A THR 131.A OG1 THR 127.A OG1 no hydrogen 3.189 N/A GLY 133.A N VAL 125.A O no hydrogen 2.908 N/A ILE 134.A N GLY 130.A O no hydrogen 2.808 N/A ARG 135.A N THR 131.A O no hydrogen 3.087 N/A ASN 136.A N GLY 132.A O no hydrogen 2.903 N/A GLY 137.A N ILE 134.A O no hydrogen 3.123 N/A LEU 138.A N GLY 133.A O no hydrogen 2.837 N/A TYR 139.A OH ASN 167.A OD1 no hydrogen 2.554 N/A GLY 140.A N TYR 120.A O no hydrogen 3.086 N/A VAL 142.A N TRP 118.A O no hydrogen 2.958 N/A ILE 143.A N ILE 44.A O no hydrogen 2.845 N/A VAL 144.A N GLY 116.A O no hydrogen 3.097 N/A ARG 145.A N LEU 46.A O no hydrogen 2.755 N/A ARG 145.A NE GLU 45.A OE1 no hydrogen 3.104 N/A ARG 145.A NH1 GLU 185.A OE2 no hydrogen 2.865 N/A ARG 145.A NH2 GLU 45.A OE1 no hydrogen 3.369 N/A ARG 145.A NH2 GLU 185.A OE1 no hydrogen 2.711 N/A ARG 145.A NH2 GLU 185.A OE2 no hydrogen 3.537 N/A ARG 146.A N ASP 149.A OD2 no hydrogen 2.627 N/A ARG 146.A NE GLU 48.A OE1 no hydrogen 2.817 N/A ARG 146.A NE GLU 48.A OE2 no hydrogen 3.441 N/A ARG 146.A NH2 GLU 48.A OE2 no hydrogen 2.762 N/A GLY 148.A N ALA 7.A O no hydrogen 2.864 N/A ASP 149.A N ARG 146.A O no hydrogen 2.906 N/A LEU 151.A N LYS 5.A O no hydrogen 2.922 N/A ASP 153.A N ARG 183.A O no hydrogen 2.802 N/A THR 155.A OG1 GLU 185.A OE1 no hydrogen 2.770 N/A HIS 156.A N GLU 185.A O no hydrogen 2.802 N/A ILE 158.A N VAL 187.A O no hydrogen 2.823 N/A VAL 159.A N ASN 166.A OD1 no hydrogen 2.771 N/A PHE 160.A N ILE 189.A O no hydrogen 2.855 N/A ASN 161.A N THR 164.A O no hydrogen 2.912 N/A ASN 161.A ND2 ILE 134.A O no hydrogen 3.028 N/A ASN 161.A ND2 ARG 135.A O no hydrogen 3.508 N/A ASN 161.A ND2 ASN 167.A OD1 no hydrogen 2.883 N/A ASP 162.A N HIS 191.A O no hydrogen 2.923 N/A THR 164.A N ASN 161.A O no hydrogen 2.936 N/A THR 164.A OG1 ASN 161.A O no hydrogen 3.045 N/A ASN 166.A N VAL 159.A O no hydrogen 2.844 N/A ASN 166.A ND2 THR 157.A O no hydrogen 3.239 N/A ASN 167.A N THR 164.A OG1 no hydrogen 3.003 N/A ASN 167.A ND2 GLN 27.A OE1 no hydrogen 3.037 N/A ASN 167.A ND2 ARG 135.A O no hydrogen 2.884 N/A ARG 168.A N ILE 165.A O no hydrogen 2.998 N/A ARG 168.A NE THR 172.A O no hydrogen 3.260 N/A ARG 168.A NH2 THR 172.A O no hydrogen 2.833 N/A HIS 171.A N GLY 262.A O no hydrogen 3.109 N/A THR 172.A N PRO 169.A O no hydrogen 3.272 N/A THR 172.A OG1 PRO 169.A O no hydrogen 2.629 N/A PHE 176.A N LEU 266.A O no hydrogen 2.843 N/A ALA 178.A N LEU 268.A O no hydrogen 2.797 N/A THR 179.A N ASP 182.A OD2 no hydrogen 2.973 N/A VAL 180.A N LYS 270.A O no hydrogen 2.905 N/A GLY 181.A N ALA 240.A O no hydrogen 2.808 N/A ASP 182.A N THR 179.A O no hydrogen 2.949 N/A ARG 183.A N ASP 153.A OD2 no hydrogen 2.823 N/A ARG 183.A NH1 GLN 237.A OE1 no hydrogen 2.835 N/A VAL 184.A N VAL 238.A O no hydrogen 2.884 N/A GLU 185.A N ARG 154.A O no hydrogen 2.916 N/A PHE 186.A N PHE 236.A O no hydrogen 2.956 N/A VAL 187.A N HIS 156.A O no hydrogen 2.909 N/A MET 188.A N PHE 234.A O no hydrogen 2.933 N/A ILE 189.A N ILE 158.A O no hydrogen 3.046 N/A THR 190.A N ASP 232.A O no hydrogen 3.016 N/A HIS 191.A N PHE 160.A O no hydrogen 2.805 N/A GLU 193.A N ASP 162.A OD1 no hydrogen 2.768 N/A HIS 196.A N CYS 228.A O no hydrogen 2.701 N/A PHE 198.A N LYS 226.A O no hydrogen 2.984 N/A HIS 199.A N HIS 252.A O no hydrogen 2.989 N/A HIS 199.A ND1 ASP 224.A O no hydrogen 2.771 N/A LEU 200.A N ASP 224.A O no hydrogen 3.276 N/A HIS 201.A N MET 250.A O no hydrogen 2.758 N/A HIS 203.A ND1 HIS 201.A O no hydrogen 2.858 N/A TRP 205.A N ILE 223.A O no hydrogen 2.987 N/A ALA 206.A N GLY 211.A O no hydrogen 2.959 N/A ASP 207.A N GLN 221.A O no hydrogen 2.980 N/A ASN 208.A ND2 MET 212.A O no hydrogen 2.808 N/A ASN 208.A ND2 ASP 218.A OD2 no hydrogen 2.985 N/A ARG 209.A NH1 ASP 149.A OD2 no hydrogen 3.026 N/A ARG 209.A NH2 ASP 149.A OD1 no hydrogen 2.948 N/A GLY 211.A N ASN 208.A OD1 no hydrogen 2.681 N/A MET 212.A N THR 210.A OG1 no hydrogen 3.033 N/A THR 214.A N ASP 218.A OD2 no hydrogen 3.397 N/A ASP 218.A N GLY 215.A O no hydrogen 3.351 N/A SER 220.A N ASP 218.A OD1 no hydrogen 2.900 N/A SER 220.A OG ASP 218.A OD1 no hydrogen 2.603 N/A ILE 223.A N TRP 205.A O no hydrogen 2.899 N/A LYS 226.A N PHE 198.A O no hydrogen 2.996 N/A LYS 226.A NZ.A ASP 207.A OD1 no hydrogen 2.904 N/A LYS 226.A NZ.A ASP 207.A OD2 no hydrogen 3.463 N/A LYS 226.A NZ.B ILE 227.A O no hydrogen 2.904 N/A CYS 228.A N HIS 196.A O no hydrogen 2.748 N/A CYS 228.A SG THR 190.A OG1 no hydrogen 3.224 N/A CYS 228.A SG HIS 196.A O no hydrogen 3.761 N/A CYS 228.A SG LYS 226.A O no hydrogen 3.825 N/A GLY 229.A N ASP 232.A OD2 no hydrogen 2.955 N/A ALA 231.A N THR 190.A O no hydrogen 2.616 N/A ASP 232.A N GLY 229.A O no hydrogen 2.923 N/A SER 233.A OG TYR 117.A O no hydrogen 2.765 N/A PHE 234.A N MET 188.A O no hydrogen 2.973 N/A PHE 236.A N PHE 186.A O no hydrogen 3.106 N/A GLN 237.A NE2 VAL 150.A O no hydrogen 2.882 N/A GLN 237.A NE2 GLU 185.A OE2 no hydrogen 3.311 N/A VAL 238.A N VAL 184.A O no hydrogen 2.919 N/A ALA 240.A N ASP 182.A O no hydrogen 2.785 N/A GLY 241.A N HIS 203.A NE2 no hydrogen 3.030 N/A GLU 242.A N ILE 239.A O no hydrogen 3.013 N/A VAL 244.A N GLY 241.A O no hydrogen 2.926 N/A GLY 245.A N GLY 241.A O no hydrogen 2.675 N/A GLY 247.A N VAL 269.A O no hydrogen 2.886 N/A TRP 249.A N PHE 267.A O no hydrogen 2.927 N/A TRP 249.A NE1 GLY 245.A O no hydrogen 3.138 N/A TYR 251.A N GLY 265.A O no hydrogen 3.099 N/A TYR 251.A OH PRO 174.A O no hydrogen 2.674 N/A HIS 252.A N HIS 199.A O no hydrogen 2.930 N/A HIS 252.A ND1 CYS 253.A O no hydrogen 2.722 N/A CYS 253.A N MET 263.A O no hydrogen 3.292 N/A CYS 253.A SG HIS 196.A ND1 no hydrogen 3.937 N/A CYS 253.A SG THR 197.A O no hydrogen 3.664 N/A CYS 253.A SG HIS 258.A ND1 no hydrogen 3.672 N/A HIS 254.A N THR 197.A O no hydrogen 2.636 N/A HIS 254.A ND1 HIS 254.A O no hydrogen 2.715 N/A SER 259.A N VAL 255.A O no hydrogen 3.025 N/A SER 259.A OG GLN 256.A O no hydrogen 3.238 N/A ASP 260.A N GLN 256.A O no hydrogen 3.065 N/A MET 261.A N SER 257.A O no hydrogen 2.862 N/A GLY 262.A N SER 259.A O no hydrogen 3.037 N/A MET 263.A N HIS 258.A O no hydrogen 2.864 N/A GLY 265.A N TYR 251.A O no hydrogen 2.911 N/A LEU 266.A N ASP 175.A OD1 no hydrogen 2.854 N/A PHE 267.A N TRP 249.A O no hydrogen 2.678 N/A LEU 268.A N PHE 176.A O no hydrogen 2.609 N/A VAL 269.A N GLY 247.A O no hydrogen 2.881 N/A LYS 270.A N ALA 178.A O no hydrogen 2.834 N/A LYS 270.A NZ GLU 177.A OE2 no hydrogen 2.914 N/A LYS 271.A N THR 275.A O no hydrogen 2.938 N/A GLY 274.A N LYS 271.A O no hydrogen 2.695 N/A THR 275.A N ASP 273.A OD1 no hydrogen 2.934 N/A THR 275.A OG1 ASP 273.A OD1 no hydrogen 2.723 N/A